LOCUS       DAVHLA010000001       154997 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVHLA010000001 DAVHLA010000000
VERSION     DAVHLA010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 154997)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 154997)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..154997
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.001"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            574..1026
                     /locus_tag="VVO77_000001"
                     /pseudo
     CDS             574..1026
                     /locus_tag="VVO77_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
     gene            1045..2382
                     /locus_tag="VVO77_000002"
     CDS             1045..2382
                     /locus_tag="VVO77_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEU5692090.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            2461..3345
                     /locus_tag="VVO77_000003"
     CDS             2461..3345
                     /locus_tag="VVO77_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU5692091.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            3345..4178
                     /locus_tag="VVO77_000004"
     CDS             3345..4178
                     /locus_tag="VVO77_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU5692092.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLITIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            4197..6290
                     /gene="nanB"
                     /locus_tag="VVO77_000005"
     CDS             4197..6290
                     /gene="nanB"
                     /locus_tag="VVO77_000005"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HEU5692093.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISSLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLREKHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSKVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            6303..7406
                     /locus_tag="VVO77_000006"
     CDS             6303..7406
                     /locus_tag="VVO77_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEU5692094.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            7580..8278
                     /locus_tag="VVO77_000007"
     CDS             7580..8278
                     /locus_tag="VVO77_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEU5692095.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            8297..9814
                     /locus_tag="VVO77_000008"
     CDS             8297..9814
                     /locus_tag="VVO77_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU5692096.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPIGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            9939..11267
                     /locus_tag="VVO77_000009"
     CDS             9939..11267
                     /locus_tag="VVO77_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU5692097.1"
                     /translation="MKFRKLACTVLAGAVVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            11519..12385
                     /locus_tag="VVO77_000010"
     CDS             11519..12385
                     /locus_tag="VVO77_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU5692098.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            12401..13240
                     /locus_tag="VVO77_000011"
     CDS             12401..13240
                     /locus_tag="VVO77_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU5692099.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            13513..13965
                     /locus_tag="VVO77_000012"
     CDS             13513..13965
                     /locus_tag="VVO77_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEU5692100.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLIEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCYEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            14098..14406
                     /locus_tag="VVO77_000013"
     CDS             14098..14406
                     /locus_tag="VVO77_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692101.1"
                     /translation="MDGQGITVDEMAWIIRGIVNALIGRYIKLGAYAAKYGISMARSI
                     LSRAAATAAARVGLSTKISGWILRVAVNVADVYGNFAYNIAAAWDAHDKIPNNGRINF
                     "
     gene            14690..15334
                     /locus_tag="VVO77_000014"
     CDS             14690..15334
                     /locus_tag="VVO77_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEU5692102.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            15503..16420
                     /locus_tag="VVO77_000015"
     CDS             15503..16420
                     /locus_tag="VVO77_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEU5692103.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            16438..17322
                     /locus_tag="VVO77_000016"
     CDS             16438..17322
                     /locus_tag="VVO77_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU5692104.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGLVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASMTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(17338..18189)
                     /locus_tag="VVO77_000017"
     CDS             complement(17338..18189)
                     /locus_tag="VVO77_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEU5692105.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKNSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            18389..20446
                     /gene="pbp2b"
                     /locus_tag="VVO77_000018"
     CDS             18389..20446
                     /gene="pbp2b"
                     /locus_tag="VVO77_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HEU5692106.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANDGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSELTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            20457..21053
                     /gene="recR"
                     /locus_tag="VVO77_000019"
     CDS             20457..21053
                     /gene="recR"
                     /locus_tag="VVO77_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEU5692107.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            21229..22272
                     /locus_tag="VVO77_000020"
     CDS             21229..22272
                     /locus_tag="VVO77_000020"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEU5692108.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVDYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALELAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            22356..23729
                     /locus_tag="VVO77_000021"
     CDS             22356..23729
                     /locus_tag="VVO77_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEU5692109.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQGLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSIQLHNQMILSLSPDVLDTVIFYGEDIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLSANDQILLKGSNSMNLAMLVE
                     SLENETK"
     gene            23716..24327
                     /locus_tag="VVO77_000022"
     CDS             23716..24327
                     /locus_tag="VVO77_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU5692110.1"
                     /translation="MKPSDFVKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQGSDLDAEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIELLWQVYQGQREQYLD"
     gene            24418..25122
                     /locus_tag="VVO77_000023"
     CDS             24418..25122
                     /locus_tag="VVO77_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEU5692111.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            25341..26714
                     /gene="ftsA"
                     /locus_tag="VVO77_000024"
     CDS             25341..26714
                     /gene="ftsA"
                     /locus_tag="VVO77_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEU5692112.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRTGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            26731..27990
                     /gene="ftsZ"
                     /locus_tag="VVO77_000025"
     CDS             26731..27990
                     /gene="ftsZ"
                     /locus_tag="VVO77_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEU5692113.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETAELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            27995..28666
                     /locus_tag="VVO77_000026"
     CDS             27995..28666
                     /locus_tag="VVO77_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEU5692114.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            28676..29215
                     /locus_tag="VVO77_000027"
     CDS             28676..29215
                     /locus_tag="VVO77_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEU5692115.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            29215..29478
                     /locus_tag="VVO77_000028"
     CDS             29215..29478
                     /locus_tag="VVO77_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEU5692116.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            29535..30260
                     /locus_tag="VVO77_000029"
     CDS             29535..30260
                     /locus_tag="VVO77_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEU5692117.1"
                     /translation="MEWIKKVEDSYAPFLTPFINPHQEKLLKILAKTYGLACSSSGEF
                     VSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHLTHAKILGTVINQLGIERKLF
                     GDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEERPFTEKIDKLEQYRELDLSV
                     SSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDKSDYTVQVGDLISVRKFGRLR
                     LLQDKGQTKKEKKKITVQLLLSK"
     gene            30269..31057
                     /gene="divIVA"
                     /locus_tag="VVO77_000030"
     CDS             30269..31057
                     /gene="divIVA"
                     /locus_tag="VVO77_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HEU5692118.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPVPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVEAPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            31405..34197
                     /locus_tag="VVO77_000031"
     CDS             31405..34197
                     /locus_tag="VVO77_000031"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEU5692119.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKIIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEAQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SDLTIAEGPAPEAALSFEDVAFTVERAAGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFADAVAEGFEEK"
     gene            34754..35041
                     /locus_tag="VVO77_000032"
     CDS             34754..35041
                     /locus_tag="VVO77_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692120.1"
                     /translation="MKSSGIVGLVGGILLLICPFVLLGTAVNTAATTLNGGATAGAFS
                     GVALLLNTLKIANLVLGIIAIVYYKGDKHVGAAPSVLMIVSGEVSLIPFLG"
     gene            35651..36343
                     /locus_tag="VVO77_000033"
     CDS             35651..36343
                     /locus_tag="VVO77_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEU5692121.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            36396..38807
                     /locus_tag="VVO77_000034"
     CDS             36396..38807
                     /locus_tag="VVO77_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEU5692122.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGRI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALVTTSYVYKGTRFE
                     REAFASFPDDLLVQRFTKEGAETLDFTIELSLTCDLASDEKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLEAVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            39057..39758
                     /locus_tag="VVO77_000035"
     CDS             39057..39758
                     /locus_tag="VVO77_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5692123.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            39760..42468
                     /locus_tag="VVO77_000036"
     CDS             39760..42468
                     /locus_tag="VVO77_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEU5692124.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGCFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NVFSSAYEEKSKQHQEELEQILSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLAFVLSLLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKAL
                     YKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLIAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(42564..43055)
                     /gene="tpx"
                     /locus_tag="VVO77_000037"
     CDS             complement(42564..43055)
                     /gene="tpx"
                     /locus_tag="VVO77_000037"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEU5692125.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGHDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(43178..44107)
                     /gene="psaA"
                     /locus_tag="VVO77_000038"
     CDS             complement(43178..44107)
                     /gene="psaA"
                     /locus_tag="VVO77_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEU5692126.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKATTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(44139..44987)
                     /locus_tag="VVO77_000039"
     CDS             complement(44139..44987)
                     /locus_tag="VVO77_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEU5692127.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(44984..45706)
                     /locus_tag="VVO77_000040"
     CDS             complement(44984..45706)
                     /locus_tag="VVO77_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEU5692128.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            45997..47889
                     /gene="pepO"
                     /locus_tag="VVO77_000041"
     CDS             45997..47889
                     /gene="pepO"
                     /locus_tag="VVO77_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEU5692129.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVATVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(48012..48641)
                     /locus_tag="VVO77_000042"
     CDS             complement(48012..48641)
                     /locus_tag="VVO77_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEU5692130.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            49637..51859
                     /locus_tag="VVO77_000043"
     CDS             49637..51859
                     /locus_tag="VVO77_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEU5692131.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            51889..52332
                     /locus_tag="VVO77_000044"
     CDS             51889..52332
                     /locus_tag="VVO77_000044"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEU5692132.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGVAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGANMQVELVNNGPVTIILDTKKR"
     gene            complement(52371..52786)
                     /locus_tag="VVO77_000045"
                     /pseudo
     CDS             complement(52371..52786)
                     /locus_tag="VVO77_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720030.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            53145..53507
                     /locus_tag="VVO77_000046"
     CDS             53145..53507
                     /locus_tag="VVO77_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692133.1"
                     /translation="MRLASESRQILDKLKDDVYNKLGYEVSYSSIVSQAVREYVPKKE
                     RIDWIKLKETAIPFSSLKQSNNWEYQTSLMLEEDVLILLSELQNFFLDVFQAKRIHRA
                     FCVRLCLKAQFLLSNNDS"
     gene            53688..53987
                     /locus_tag="VVO77_000047"
     CDS             53688..53987
                     /locus_tag="VVO77_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692134.1"
                     /translation="MNRDVLEFLRTETAEKISLYISEANRLEGDVTLLAPSSQDLEDI
                     KNAMLSNSNLGLKVARLDVMKKIAYASTRNHYLTGATIFGDISKGTYNCDPKSYV"
     gene            complement(54082..54519)
                     /locus_tag="VVO77_000048"
     CDS             complement(54082..54519)
                     /locus_tag="VVO77_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692135.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLA
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMP
                     IITACHSTFYYMTADYLGENYPDFYDKHISNTYTILSISSFLV"
     gene            complement(54621..55286)
                     /locus_tag="VVO77_000049"
     CDS             complement(54621..55286)
                     /locus_tag="VVO77_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEU5692136.1"
                     /translation="MAIASGYLNSRLDKFVDWGPWTALVPFGLISVTNVGISMLSTRF
                     TGKLSKWGNYFGIVNTILSGAIDYILGNKAAIITYPVTFLIYTFAIKKWKASQEGRPN
                     QMSQKQVKLAAIIISIIAFLFAFVTNYIGYEGKMNLLAYVTTIAFALSLIANALNALK
                     LTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNAIGALFVWNDEEVRYIEGNSN
                     KEY"
     gene            complement(55474..56124)
                     /locus_tag="VVO77_000050"
     CDS             complement(55474..56124)
                     /locus_tag="VVO77_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEU5692137.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            56236..57078
                     /locus_tag="VVO77_000051"
     CDS             56236..57078
                     /locus_tag="VVO77_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEU5692138.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADAQQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQENFDRLVTHPPCDIAVY
                     GHIHQQLLRHGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDGKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            57154..57591
                     /locus_tag="VVO77_000052"
     CDS             57154..57591
                     /locus_tag="VVO77_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEU5692139.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            57660..57962
                     /locus_tag="VVO77_000053"
     CDS             57660..57962
                     /locus_tag="VVO77_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692140.1"
                     /translation="MYLVIEIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFTFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(58053..59126)
                     /locus_tag="VVO77_000054"
     CDS             complement(58053..59126)
                     /locus_tag="VVO77_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEU5692141.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSRQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYHAWKNR"
     gene            59282..59959
                     /locus_tag="VVO77_000055"
     CDS             59282..59959
                     /locus_tag="VVO77_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU5692142.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            59952..60926
                     /locus_tag="VVO77_000056"
     CDS             59952..60926
                     /locus_tag="VVO77_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEU5692143.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLFLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(60975..62918)
                     /gene="thrS"
                     /locus_tag="VVO77_000057"
     CDS             complement(60975..62918)
                     /gene="thrS"
                     /locus_tag="VVO77_000057"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEU5692144.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNIAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVNYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(62976..63299)
                     /locus_tag="VVO77_000058"
     CDS             complement(62976..63299)
                     /locus_tag="VVO77_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEU5692145.1"
                     /translation="MELQELVEHSWAIRQAYHELEVKHHDSKWTVEEDLLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENFLSDKEKQLN
                     VRTWK"
     gene            64164..64709
                     /locus_tag="VVO77_000059"
     CDS             64164..64709
                     /locus_tag="VVO77_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001852743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEU5692146.1"
                     /translation="MKLAVIAANGQVGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAES
                     LYIDETKTTRLLDTSDFPEEFKSLAKAQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKRNKPD"
     gene            64935..65204
                     /gene="rpsO"
                     /locus_tag="VVO77_000060"
     CDS             64935..65204
                     /gene="rpsO"
                     /locus_tag="VVO77_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEU5692147.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            66020..66634
                     /locus_tag="VVO77_000061"
     CDS             66020..66634
                     /locus_tag="VVO77_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEU5692148.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(66927..67676)
                     /locus_tag="VVO77_000062"
     CDS             complement(66927..67676)
                     /locus_tag="VVO77_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEU5692149.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMILKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            67809..70145
                     /locus_tag="VVO77_000063"
     CDS             67809..70145
                     /locus_tag="VVO77_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HEU5692150.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRKSMLRALPSALMVVFSVLFVKIF
                     GSSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTGQTLPVYGVMMLVFTVIFILTSRYQAKK"
     gene            70246..70923
                     /locus_tag="VVO77_000064"
     CDS             70246..70923
                     /locus_tag="VVO77_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEU5692151.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVPHVSK"
     gene            70910..71707
                     /locus_tag="VVO77_000065"
     CDS             70910..71707
                     /locus_tag="VVO77_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEU5692152.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            71724..72827
                     /locus_tag="VVO77_000066"
     CDS             71724..72827
                     /locus_tag="VVO77_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEU5692153.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWLSKRRNKAWYKMARLGADFYVDLLADLEKSGQEIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLSILDQAPANELFPGLQGFDNLLYASGGARVDGHLLVTRL
                     LEASQVKLVKEKVTLTLLSSGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EAALPHYPVLARVTSRAERVGIRAYTSDFSPFFGQVPELAGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPENYPIENYVKRVKSE"
     gene            72834..73025
                     /locus_tag="VVO77_000067"
     CDS             72834..73025
                     /locus_tag="VVO77_000067"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692154.1"
                     /translation="MKIKEQTRKLAADYSKHCFEVVDRTDEVSSKHCFEVVDRTDEVS
                     NHTHGKATLTWFELDFRRV"
     gene            73128..74147
                     /gene="galE"
                     /locus_tag="VVO77_000068"
     CDS             73128..74147
                     /gene="galE"
                     /locus_tag="VVO77_000068"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU5692155.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTDTLRDIFKQEEPTGIIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            74149..75114
                     /locus_tag="VVO77_000069"
     CDS             74149..75114
                     /locus_tag="VVO77_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU5692156.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIINFSDFPLIIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKNKVKRL"
     gene            complement(75165..75371)
                     /locus_tag="VVO77_000070"
     CDS             complement(75165..75371)
                     /locus_tag="VVO77_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEU5692157.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            75423..75899
                     /locus_tag="VVO77_000071"
     CDS             75423..75899
                     /locus_tag="VVO77_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEU5692158.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            75908..76579
                     /locus_tag="VVO77_000072"
     CDS             75908..76579
                     /locus_tag="VVO77_000072"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEU5692159.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            76709..77047
                     /locus_tag="VVO77_000073"
     CDS             76709..77047
                     /locus_tag="VVO77_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEU5692160.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLADGDTVTLIKDLKVKGAPKDLKQGTRVKNIHIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            77050..77679
                     /locus_tag="VVO77_000074"
     CDS             77050..77679
                     /locus_tag="VVO77_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEU5692161.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITKHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            77919..79070
                     /locus_tag="VVO77_000075"
     CDS             77919..79070
                     /locus_tag="VVO77_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU5692162.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGARLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            79388..80137
                     /gene="truA"
                     /locus_tag="VVO77_000076"
     CDS             79388..80137
                     /gene="truA"
                     /locus_tag="VVO77_000076"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEU5692163.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQAI
                     TVHGAGRTDSGVHALGQVIHFDLPYQIDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            80127..80900
                     /locus_tag="VVO77_000077"
     CDS             80127..80900
                     /locus_tag="VVO77_000077"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEU5692164.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            80878..81339
                     /locus_tag="VVO77_000078"
     CDS             80878..81339
                     /locus_tag="VVO77_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU5692165.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
     gene            complement(81598..81801)
                     /locus_tag="VVO77_000079"
     CDS             complement(81598..81801)
                     /locus_tag="VVO77_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU5692166.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(81794..82876)
                     /locus_tag="VVO77_000080"
     CDS             complement(81794..82876)
                     /locus_tag="VVO77_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEU5692167.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(83002..83784)
                     /locus_tag="VVO77_000081"
     CDS             complement(83002..83784)
                     /locus_tag="VVO77_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEU5692168.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(83784..85127)
                     /locus_tag="VVO77_000082"
     CDS             complement(83784..85127)
                     /locus_tag="VVO77_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEU5692169.1"
                     /translation="MNLKTTLGLLAGRSSHFILSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGTYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDVQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(85226..86542)
                     /locus_tag="VVO77_000083"
     CDS             complement(85226..86542)
                     /locus_tag="VVO77_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEU5692170.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQNLDKLPEKL
                     GILGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDINGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            86735..87961
                     /locus_tag="VVO77_000084"
     CDS             86735..87961
                     /locus_tag="VVO77_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEU5692171.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPRVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYILWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            88160..89734
                     /locus_tag="VVO77_000085"
     CDS             88160..89734
                     /locus_tag="VVO77_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU5692172.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQNIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            89998..90786
                     /gene="codY"
                     /locus_tag="VVO77_000086"
     CDS             89998..90786
                     /gene="codY"
                     /locus_tag="VVO77_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEU5692173.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGQLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            90786..91361
                     /locus_tag="VVO77_000087"
     CDS             90786..91361
                     /locus_tag="VVO77_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEU5692174.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDFFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            91443..91528
                     /locus_tag="VVO77_000088"
     tRNA            91443..91528
                     /locus_tag="VVO77_000088"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:91477..91479,aa:Leu,seq:aag)
     gene            91811..92941
                     /gene="ugpC"
                     /locus_tag="VVO77_000089"
     CDS             91811..92941
                     /gene="ugpC"
                     /locus_tag="VVO77_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEU5692175.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFITVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(93063..93233)
                     /locus_tag="VVO77_000090"
     CDS             complement(93063..93233)
                     /locus_tag="VVO77_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692176.1"
                     /translation="MEIKEQTRKLAVSCSKYIFEVADKTDEISNHTYGKATLTWFEEI
                     FEEYKEHHNIDA"
     gene            93440..94198
                     /locus_tag="VVO77_000091"
     CDS             93440..94198
                     /locus_tag="VVO77_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEU5692177.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            94286..94798
                     /locus_tag="VVO77_000092"
     CDS             94286..94798
                     /locus_tag="VVO77_000092"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEU5692178.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            94980..95924
                     /locus_tag="VVO77_000093"
     CDS             94980..95924
                     /locus_tag="VVO77_000093"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEU5692179.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            95933..96610
                     /locus_tag="VVO77_000094"
     CDS             95933..96610
                     /locus_tag="VVO77_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEU5692180.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            96708..97466
                     /locus_tag="VVO77_000095"
     CDS             96708..97466
                     /locus_tag="VVO77_000095"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEU5692181.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            97504..99009
                     /gene="lytC"
                     /locus_tag="VVO77_000096"
     CDS             97504..99009
                     /gene="lytC"
                     /locus_tag="VVO77_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HEU5692182.1"
                     /translation="MSVTFFIGEQRLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRNGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            99505..100023
                     /locus_tag="VVO77_000097"
     CDS             99505..100023
                     /locus_tag="VVO77_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEU5692183.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            100153..100659
                     /locus_tag="VVO77_000098"
     CDS             100153..100659
                     /locus_tag="VVO77_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEU5692184.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQDQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            100659..100829
                     /locus_tag="VVO77_000099"
     CDS             100659..100829
                     /locus_tag="VVO77_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692185.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            100861..102093
                     /gene="clpX"
                     /locus_tag="VVO77_000100"
     CDS             100861..102093
                     /gene="clpX"
                     /locus_tag="VVO77_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEU5692186.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            102102..102689
                     /locus_tag="VVO77_000101"
     CDS             102102..102689
                     /locus_tag="VVO77_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEU5692187.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            102700..103080
                     /locus_tag="VVO77_000102"
     CDS             102700..103080
                     /locus_tag="VVO77_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEU5692188.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            103132..104022
                     /gene="rapZ"
                     /locus_tag="VVO77_000103"
     CDS             103132..104022
                     /gene="rapZ"
                     /locus_tag="VVO77_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEU5692189.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLVQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            104019..104996
                     /locus_tag="VVO77_000104"
     CDS             104019..104996
                     /locus_tag="VVO77_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEU5692190.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDFRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            104993..105904
                     /gene="whiA"
                     /locus_tag="VVO77_000105"
     CDS             104993..105904
                     /gene="whiA"
                     /locus_tag="VVO77_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEU5692191.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(105938..106906)
                     /locus_tag="VVO77_000106"
     CDS             complement(105938..106906)
                     /locus_tag="VVO77_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEU5692192.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELESVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            107042..107899
                     /locus_tag="VVO77_000107"
     CDS             107042..107899
                     /locus_tag="VVO77_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEU5692193.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYMSTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            107886..108665
                     /locus_tag="VVO77_000108"
     CDS             107886..108665
                     /locus_tag="VVO77_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEU5692194.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            108689..110041
                     /locus_tag="VVO77_000109"
     CDS             108689..110041
                     /locus_tag="VVO77_000109"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEU5692195.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGNIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            110115..110489
                     /locus_tag="VVO77_000110"
     CDS             110115..110489
                     /locus_tag="VVO77_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEU5692196.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            110491..111339
                     /locus_tag="VVO77_000111"
     CDS             110491..111339
                     /locus_tag="VVO77_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU5692197.1"
                     /translation="MKLAVFTDSSAYLSEETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            111616..112383
                     /locus_tag="VVO77_000112"
     CDS             111616..112383
                     /locus_tag="VVO77_000112"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEU5692198.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMHIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            112395..113579
                     /locus_tag="VVO77_000113"
     CDS             112395..113579
                     /locus_tag="VVO77_000113"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEU5692199.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHNPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLENISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            113576..115447
                     /locus_tag="VVO77_000114"
     CDS             113576..115447
                     /locus_tag="VVO77_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU5692200.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELDRAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKVEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(115590..116774)
                     /gene="mntE"
                     /locus_tag="VVO77_000115"
     CDS             complement(115590..116774)
                     /gene="mntE"
                     /locus_tag="VVO77_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HEU5692201.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLATGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            117078..119774
                     /locus_tag="VVO77_000116"
     CDS             117078..119774
                     /locus_tag="VVO77_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEU5692202.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LLEANSLKIEEAALTGESVPVEKDLSVDLATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            119787..120578
                     /gene="yghU"
                     /locus_tag="VVO77_000117"
     CDS             119787..120578
                     /gene="yghU"
                     /locus_tag="VVO77_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HEU5692203.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRQTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTEDVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QENLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            120694..121104
                     /locus_tag="VVO77_000118"
     CDS             120694..121104
                     /locus_tag="VVO77_000118"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEU5692204.1"
                     /translation="MEKKIVKDNLFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            121116..122711
                     /locus_tag="VVO77_000119"
     CDS             121116..122711
                     /locus_tag="VVO77_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692205.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPRSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESINGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
     gene            122878..123042
                     /locus_tag="VVO77_000120"
     CDS             122878..123042
                     /locus_tag="VVO77_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HEU5692206.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            123121..123849
                     /gene="yaaA"
                     /locus_tag="VVO77_000121"
     CDS             123121..123849
                     /gene="yaaA"
                     /locus_tag="VVO77_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEU5692207.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(124127..124675)
                     /locus_tag="VVO77_000122"
     CDS             complement(124127..124675)
                     /locus_tag="VVO77_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU5692208.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALASKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIK"
     gene            124996..125505
                     /locus_tag="VVO77_000123"
     CDS             124996..125505
                     /locus_tag="VVO77_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEU5692209.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISGSFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQVDQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GLWNYPTVF"
     gene            125481..126668
                     /locus_tag="VVO77_000124"
     CDS             125481..126668
                     /locus_tag="VVO77_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU5692210.1"
                     /translation="MELSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTVILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            126661..127026
                     /locus_tag="VVO77_000125"
     CDS             126661..127026
                     /locus_tag="VVO77_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU5692211.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGAPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            127042..128388
                     /gene="asnS"
                     /locus_tag="VVO77_000126"
     CDS             127042..128388
                     /gene="asnS"
                     /locus_tag="VVO77_000126"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEU5692212.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            128541..128831
                     /locus_tag="VVO77_000127"
     CDS             128541..128831
                     /locus_tag="VVO77_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEU5692213.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            128843..129313
                     /gene="ssbA"
                     /locus_tag="VVO77_000128"
     CDS             128843..129313
                     /gene="ssbA"
                     /locus_tag="VVO77_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEU5692214.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            129345..129584
                     /locus_tag="VVO77_000129"
     CDS             129345..129584
                     /locus_tag="VVO77_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEU5692215.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            129879..131279
                     /locus_tag="VVO77_000130"
     CDS             129879..131279
                     /locus_tag="VVO77_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEU5692216.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            131281..131640
                     /locus_tag="VVO77_000131"
     CDS             131281..131640
                     /locus_tag="VVO77_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEU5692217.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            131694..132443
                     /locus_tag="VVO77_000132"
     CDS             131694..132443
                     /locus_tag="VVO77_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEU5692218.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVNPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            132433..132732
                     /locus_tag="VVO77_000133"
     CDS             132433..132732
                     /locus_tag="VVO77_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEU5692219.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            132803..133738
                     /locus_tag="VVO77_000134"
     CDS             132803..133738
                     /locus_tag="VVO77_000134"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEU5692220.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            133824..134336
                     /locus_tag="VVO77_000135"
     CDS             133824..134336
                     /locus_tag="VVO77_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEU5692221.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAPGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            134361..134969
                     /locus_tag="VVO77_000136"
     CDS             134361..134969
                     /locus_tag="VVO77_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEU5692222.1"
                     /translation="MFGELIRYLDQYEDVILREIKAQFPDVAVDKLMEEYIKAGLILR
                     ENKRYYLNFPTLESLDSLELDQEIFVREASPVYQALLEQSFETELRNQINAAILVEKT
                     DFARIKMTLSNYFYKVKQQYPLTEKQQELYDILGDVNPEYALKYMTAFLLKFLKKDQL
                     MQKCRDIFVDSLVVLGYIVQNEDGKYELAIDFDKERLTFYLA"
     gene            135070..135267
                     /locus_tag="VVO77_000137"
     CDS             135070..135267
                     /locus_tag="VVO77_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEU5692223.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTKE"
     gene            complement(135310..136755)
                     /locus_tag="VVO77_000138"
     CDS             complement(135310..136755)
                     /locus_tag="VVO77_000138"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEU5692224.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVVFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQSYLVRRVYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            136861..138483
                     /locus_tag="VVO77_000139"
     CDS             136861..138483
                     /locus_tag="VVO77_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEU5692225.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEDSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            138686..140644
                     /locus_tag="VVO77_000140"
     CDS             138686..140644
                     /locus_tag="VVO77_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU5692226.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            140816..141361
                     /locus_tag="VVO77_000141"
     CDS             140816..141361
                     /locus_tag="VVO77_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5692227.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDMSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILPLSNISEKYSRRLQEEI"
     gene            141370..141909
                     /locus_tag="VVO77_000142"
     CDS             141370..141909
                     /locus_tag="VVO77_000142"
                     /inference="COORDINATES: protein motif:HMM:NF012869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5692228.1"
                     /translation="MTEKIQEHELIKTNQAEKSVQDVLDNCIERVQNNSLKSDRVTSF
                     ETSFALLFIFATIVVMLTYGGYRVSAGYISVGTLVSFLIYLFQLLNPISNIANFVTVY
                     SRSKGSSVALDNLLAVPKEKFEGGKSVSGQGLNFNHVYFGYDENRPVLKDITCSIFKG
                     QKLLLLDHLDQENQRLCVC"
     gene            141945..142490
                     /locus_tag="VVO77_000143"
     CDS             141945..142490
                     /locus_tag="VVO77_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5692229.1"
                     /translation="MEQSSIYDFNLKEWRSKIAWVSQNNAVLSGSIRDNLCLGLNRLV
                     TDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRFLSGGQSQRLQIARTYLKDAEILI
                     FDEATANLDADSEYAIISSLYSVLKEKTVVIIAHSLSTVKDVDCIFFLEEGKITGSGT
                     HKELLENHERYARFVQEQMIE"
     gene            142647..143741
                     /locus_tag="VVO77_000144"
     CDS             142647..143741
                     /locus_tag="VVO77_000144"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEU5692230.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSGFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQAIEG"
     gene            143749..144915
                     /locus_tag="VVO77_000145"
     CDS             143749..144915
                     /locus_tag="VVO77_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU5692231.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            145008..148106
                     /locus_tag="VVO77_000146"
     CDS             145008..148106
                     /locus_tag="VVO77_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU5692232.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVSDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPRQATQVQADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGLTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            148154..148771
                     /locus_tag="VVO77_000147"
     CDS             148154..148771
                     /locus_tag="VVO77_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEU5692233.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPITEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            148782..150116
                     /locus_tag="VVO77_000148"
     CDS             148782..150116
                     /locus_tag="VVO77_000148"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEU5692234.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            150126..150590
                     /locus_tag="VVO77_000149"
     CDS             150126..150590
                     /locus_tag="VVO77_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU5692235.1"
                     /translation="MEIPIKIIQASKFDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQCLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEEILLYATSQGYSMIWFNPFYLEEQ"
     gene            150587..151081
                     /locus_tag="VVO77_000150"
     CDS             150587..151081
                     /locus_tag="VVO77_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU5692236.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            151162..152817
                     /gene="mltG"
                     /locus_tag="VVO77_000151"
     CDS             151162..152817
                     /gene="mltG"
                     /locus_tag="VVO77_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEU5692237.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     IRDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQTVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            152888..153370
                     /gene="greA"
                     /locus_tag="VVO77_000152"
     CDS             152888..153370
                     /gene="greA"
                     /locus_tag="VVO77_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEU5692238.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            153698..154096
                     /locus_tag="VVO77_000153"
     CDS             153698..154096
                     /locus_tag="VVO77_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU5692239.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
     gene            154541..154936
                     /locus_tag="VVO77_000154"
                     /pseudo
     CDS             154541..154936
                     /locus_tag="VVO77_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
BASE COUNT        46172 a        28513 c        34872 g        45440 t
ORIGIN      
        1 taattgaaaa cggtaacaaa actaatttag agaatgaaat atagagtatt tctctcttaa
       61 aagtttttgg tgaaacgaga tgtagaaagg agatttagcc aaagagtcta ttagtgctag
      121 aataatagat tagaattatt ttagaaaaac gaagtgagca gcttataaat tcaagtcccc
      181 aaatagattc atactagtat cttttgcaaa aaataaaggg cgacttcctt catgaatatc
      241 aatttcatct ataaggaagg tagctaattg aactaactta tttattctgt ttgtcgctag
      301 aaaaatcaga cctccttgtg aagattgagg agatacttaa tgaaaatcaa agaagaaact
      361 agcaagctag tagcagattg cccaaaacac cgctttgagg ttgtagataa gactgacgta
      421 tataatccaa ggtgaagcga ctgtggtttg aagagatttt caaagagtat aggctagaga
      481 gtagtgtttt tatgtccttc tagtagaaaa tgctagacag aagaatgggg aacttggata
      541 ggaaaaatag attgagaaag gaggttagaa gagatgatta ttacaaaaat tagccgttta
      601 ggaacttatg tgggagtaaa tccacatttt gcaacattaa tagattttct agaaaaaaca
      661 ggactagaaa atttaacaga aggttcgatt gttatcgatg gtaatcgatt gtttgggaat
      721 tgatttactt atctagcaga tggtcaagca ggggctttct ttgaaacaca ccaaaaatat
      781 ttggatattc atttagtttt ggaaaacgaa gaagccatgg ctgttacatc gccggaaaat
      841 gtaagcgtta cccaagaata tgatgaagag aaagatattg aattatacac agggaaagtg
      901 gaacagttgg ttcatttgag agctggcgaa tgcctcatca cttttccaga agatttacat
      961 caacccaagg ttcgtataaa tgatgaacct gtgaaaaaag ttgtctttaa agttgcgatt
     1021 tcttaatgta gaaagagaag aacgatgaaa aaaatgagaa agtttttatg tctagctgga
     1081 attgcgctag cggctgttgc cttggtagct tgttcaggaa aaaaagaagc tacaactagt
     1141 actgaaccac caacagaatt atctggtgag attacaatgt ggcactcctt tactcaagga
     1201 ccccgtttag aaagtattca aaaatcagca gatgctttca tgcaaaagca tccaaaaacg
     1261 aaaatcaaga ttgaaacatt ttcttggaat gacttctata ctaaatggac tacaggttta
     1321 gcaaatggaa atgtgccaga tatcagtaca gctcttccta accaagtaat ggaaatggtc
     1381 aactcagatg ctttggttcc gctaaatgat tctatcaagc gtattggaca agataaattt
     1441 aacgaaactg ccttaaatga agcaaaaatc ggagatgatt actactctgt tcctctttat
     1501 tcacatgcac aagtcatgtg ggttagaaca gatttgttaa aagaacataa tattgaggtt
     1561 cctaaaactt gggatcaact ctatgaagct tctaaaaaat tgaaagaagc tggagtttat
     1621 ggcttgtctg ttccgtttgg aacaaatgac ttaatggcaa cacgtttctt gaacttctac
     1681 gtacgtagtg gtggaggaag cctcttaaca aaagatctta aagcagactt gacaagccaa
     1741 cttgctcaag atggtattaa atactgggtt aaattgtata aagaaatctc acctcaagat
     1801 tctttgaact ttaatgtcct tcaacaagct accttgttct atcaaggaaa aacagcattt
     1861 gactttaact ctggcttcca tatcggagga attaatgcca acagtcctca attgattgat
     1921 tcgattgatg cttatcctat tccaaaaatc aaagagtctg ataaagacca aggaattgaa
     1981 acctcaaaca ttccaatggt tgtttggaaa aattcaaaac atccagaagt tgctaaagca
     2041 ttcttagaag cactttataa tgaagaagac tacgttaaat tccttgattc aactccagta
     2101 ggtatgttgc caactattaa ggggattagc gattctgcag cctataaaga aaatgaaact
     2161 cgtaagaagt ttaaacatgc tgaagaagta attactgaag ctgttaaaaa aggtactgct
     2221 attggttatg aaaatggacc aagtgtacaa gctggtatgt tgactaacca acacattatt
     2281 gaacaaatgt tccaagatat cattacaaat ggaacagatc ctatgaaagc agcaaaagaa
     2341 gcagaaaaac aattaaacga tttatttgag gctgttcagt agatgtaaaa gactagaaaa
     2401 taggtgggct agtgagctga aaagctctag cccaatcttg taaaagaagg gagaaggaga
     2461 atggttaaag aacgtaattt aactcgctgg atatttgttt tgccagctat gattatcgta
     2521 ggattactct ttgtttatcc gtttttctcg agtatttttt atagctttac caataagcat
     2581 ttgattatgc ctaattataa atttgttggt ttggctaact ataaagctgt gctatcagat
     2641 cccaacttct ttaatgcgtt ctttaattca attaagtgga ccgttttctc attagttggt
     2701 caagttttag tagggtttgt attggcttta gctcttcaca gagtacgcca cttcaagaaa
     2761 ttatatagga ccttattgat tgttccttgg gcatttccta ccatcgttat tgccttttct
     2821 tggcagtgga ttctaaacgg ggtttatggc tacttaccta atctaatcgt aaaattaggt
     2881 ttaatggaac atacacctgc atttttgaca gatagtacat gggcattcct atgtttggtg
     2941 tttatcaaca tttggtttgg agcaccaatg attatggtta atgtgctttc agctttgcaa
     3001 acagtaccag aagaacaatt tgaggctgct aagatagatg gtgcttcaag ttggcaggtg
     3061 ttcaagttta tcgtctttcc acatattaaa gtggttgtag gacttctagt tgttttgaga
     3121 actgtatgga tctttaataa ctttgacatt atctacctca ttactggtgg tggaccagcc
     3181 aatgctacaa cgacgcttcc aatttttgct tacaacctgg gttggggaac taaattgttg
     3241 ggtcgtgctt cagcagttac agtattgctc tttatcttct tggtggcgat ttgctttatc
     3301 tactttgcta tcatcagtaa gtgggaaaag gagggtagaa aataatgaag aagaaatcca
     3361 gtatttattt agatattctc tcacatgtac ttttagttgg tgcgaccatc gttgcaattt
     3421 tcccattggt atggattatc atatcttctg tcaaagggaa aggggaatta actcagtatc
     3481 caacacgatt ttggcctgaa cagtttacat tagattattt cactcatgtt atcaacgatt
     3541 tgcacttcat tgataacatt cgaaacagtt taatcattgc cttggctaca accctcatta
     3601 cgattattat ttctgctatg gcagcctatg gtattgttcg attctttcct aaattgggag
     3661 caatcatgtc gagactactc gtcattacct atattttccc accaattttg ttagcaattc
     3721 cctattcaat tgccattgct aaagttgggt taacaaatag tttatttggc ttgatgatgg
     3781 tttatctatc ttttagtgtt ccatatgcag tttggctctt agttggattt ttccaaacag
     3841 ttccaattgg aattgaagaa gcggctagaa ttgatggtgc aaataaattt gttacgtttt
     3901 ataaagttgt gctaccgatt gtagcaccag gtattgtagc aacagctatt tatacattta
     3961 tcaatgcttg gaatgaattc ctgtatgcct tgattttgat taacaataca ggaaagatga
     4021 cagtagcagt agcccttcgt tcacttaatg gttcagaaat actagactgg ggagatatga
     4081 tggcagcgtc tgttattgta gttcttccat caattatttt cttctctatc atccaaaata
     4141 agattgcaag tggattatca gaaggatctg tgaagtagac gaaagaagga aaaaaaatga
     4201 ataaaagagg tctttattca aaactaggaa tttctgttgt aggcattagt cttttaatgg
     4261 gagttcctac tttgattcat gcgaatgaat taaactatgg tcaactgtcc atatctccta
     4321 tttttcaagg aggttcatat caactgaaca ataagagtat agatatcagc tctttgttat
     4381 tagataaatt gtctggagag agtcagacag tagtaatgaa atttaaagca gatgaaccaa
     4441 actctcttca agctttgttt ggcctatcta atagtaaagc aggctttaaa aataattact
     4501 tttcaatttt catgagagat tctggtgaga taggtgtaga aataagagac gcccaaaagg
     4561 gaataaatta tttattttct agaccagctt cattatgggg aaagcataaa ggacaggcag
     4621 ttgaaaatac actagtattt gtatctgatt ctaaagataa aacatacaca atgtatgtta
     4681 atggaataga agtgttctct gaaacagttg atacattttt gccaatttca aatataaatg
     4741 gtatagataa ggcaacacta ggagctgtta atcgtgaagg taaggaacat tacctcgcaa
     4801 aaggaagtat tgatgaaatc agtctattta acaaagcaat tagtgatcag gaagtttcaa
     4861 atattccctt gtcaaatcca tttcagttaa ttttccaatc aggagattct actcaagcta
     4921 actattttag aataccgaca ctatatacat taagtagtgg aagagttcta tcaagtattg
     4981 atgcacgtta tggtgggact catgattcta aaagtaagat taatattgcc acttcttata
     5041 gtgatgataa tgggaaaacg tggagtgagc caatttttgc tatgaagttt aatgactatg
     5101 aggagcagtt agtttactgg ccacgagata ataaattaaa gaatagtcaa attagtggaa
     5161 gtgcttcatt catagattca tccattgttg aagataaaaa atctgggaaa acgatattac
     5221 tagctgatgt tatgcctgcg ggtattggaa ataataatgc aaataaagcc gactcaggtt
     5281 ttaaagaaat aaatggtcat tattatttaa aactaaagaa gaatggagat aacgatttcc
     5341 gttatacagt tagagaaaat ggtgtcgttt atgatgaaac aactaataaa cctacaaatt
     5401 atactataaa tgataagtat gaagttttgg agggaggaaa gtctttaaca gtcgaacaat
     5461 attcggttga ttttgatagt ggctctttaa gagaaaaaca taatggaaaa caggtcccta
     5521 tgaatgtttt ctacaaagat tcgttattta aagtgactcc tactaattat atagcaatga
     5581 caactagtca gaatagagga gagagttggg aacaatttaa gttgttgcct ccgttcttag
     5641 gagaaaaaca taatggaact tacttatgtc ccggacaagg tttagcatta aaatcaagta
     5701 acagattgat ttttgcaaca tatactagtg gagaactaac ctatctcatt tctgatgata
     5761 gtggtcaaac atggaagaaa tcctcagctt caattccgtt taaaaatgca acagcagaag
     5821 cacaaatggt tgaactgaga gatggtgtga ttagaacatt ctttagaacc actacaggta
     5881 agatagctta tatgactagt agagattctg gagaaacatg gtcgaaagtt tcgtatattg
     5941 atggaatcca acaaacttca tatggcacac aagtatctgc aattaaatac tctcaattaa
     6001 ttgatggaaa agaagcagtc attttgagta caccaaattc tagaagtggc cgtaagggag
     6061 gtcaattagt tgttggttta gtcaataaag aagatgatag tattgattgg aaataccact
     6121 atgatattga tttgccttcg tatggttatg cctattctgc gattacagaa ttgccaaatc
     6181 atcacatagg tgtgctgttt gaaaaatatg attcgtggtc gagaaatgaa ttgcatttaa
     6241 gcaatgtagt tcagtatata gatttggaaa ttaatgattt aacaaaataa aggagaaaaa
     6301 acatggttaa atacggtgtt gttggagcag ggtattttgg agctgaattg gctcgctaca
     6361 tgcaaaagaa tgatggagca gagattactc ttctctatga tccagataat gcagaggcga
     6421 ttgcagaaga attgggagca aaagtagcaa gttccttaga tgagttggtt tctagcgatg
     6481 aagtagattg tgttatcgtc gcaactccaa ataatcttca taaggaaccg gttattaagg
     6541 ctgcacagca tggtaaaaat gttttctgtg aaaaaccaat tgcgctttct tatcaagatt
     6601 gtcgcgagat ggtagatgcg tgtaaagaaa acaatgtaac ctttatggca ggacatatta
     6661 tgaatttctt taatggtgtt catcatgcaa aagaactcat taatcaagga gttatcggag
     6721 acgttctata ttgtcataca gctcgtaatg gttgggaaga acaacaaccg tcagtatcat
     6781 ggaaaaaaat tcgtgaaaaa tcaggtggtc acttgtatca ccacatccat gaattggatt
     6841 gcgttcaatt ccttatgggg ggcatgcctg aaactgtaac catgacaggt ggaaatgtgg
     6901 cccatgaagg tgaacatttc ggtgatgaag atgatatgat ttttgtcaat atggaatttt
     6961 ctaataagcg ttttgccttg ttagaatggg gttcagctta tcgttggggt gaacattatg
     7021 tcttaatcca aggaagcaaa ggtgccatcc gcttagactt attcaactgt aaaggaactc
     7081 ttaagctaga tgggcaagaa agctatttct tgattcacga atcgcaagaa gaagatgatg
     7141 atcggactcg tatctatcat agtacagaga tggatggagc aattgcttat ggtaaaccag
     7201 gtaaacgtac tccattatgg ctatcatctg tcattgataa agaaatgcgc tatctgcatg
     7261 agattatgga aggagcccca gtatcagaag aatttgcaaa acttttgaca ggtgaagctg
     7321 ccctagaagc aattgctact gcagatgctt gtacccagtc tatgtttgaa gatcgcaaag
     7381 taaaattgtc agaaattgta aaataaattt tggtattctc ctatttatag gtcgacttgc
     7441 tcctctgaaa gtacttttag aggagctgtt tgactttgct agtttttgaa actgaaatct
     7501 attatactac aaactattga aagcgtttta attttaaggt ataataatct catagaaata
     7561 aagaaaagga ggaaagagga tgccacagat tagcaaagaa gccttgattg agcaaatcaa
     7621 agatggaatc atcgtttctt gtcaggctct tcctcatgaa ccgctttata cagaagcggg
     7681 aggggtgatt cccttgctgg tcaaagcggc tgagcaaggt ggagcagtcg gtatccgagc
     7741 aaacagtgtt cgcgatatca aggaaattaa ggaagtcact aaacttccaa tcattgggat
     7801 tatcaaacgt gattatccac ctcaggaacc cttcatcacg gctactatga aagaagttga
     7861 tgaattggca gaactggaca tcgaggtgat tgctctggat tgtaccaagc gtgaacgcta
     7921 cgatggtttg gaaattcaag agttcattcg tcaggttaag gagaaatatc ctaatcagct
     7981 tttgatggct gatactagta tcttcgaaga agggctagca gctgtagaag caggaattga
     8041 ctttgtcgga acaaccttat caggctacac atcctacagt ccaaaagtag acggtccaga
     8101 ttttgaattg attaagaaac tctgtgatgc cggtgtagat gtcattgcag aaggaaaaat
     8161 tcatacacca gaacaagcca aacaaatcct tgaatatgga gtgcgaggca tcgttgttgg
     8221 tggcgccatt actagaccaa aagagattac agaacgcttc gttgctagtc ttaaataaga
     8281 tgtgagaggg agttttatgt ttaaagtttt acaaaaagtt ggaaaagctt ttatgttacc
     8341 tatagctata cttcctgcag caggtctact tttggggatt ggtggtgcac tttcaaaccc
     8401 aaccacgata gcaacttatc caatactaga caatagtatt tttcaatcaa tattccaagt
     8461 aatgagctct gcaggagagg ttgtattcag taatttgtca ctacttctct gtgtgggatt
     8521 atgtattggc ttagcgaaac gagataaagg aaccgctgcg ttagcaggag taactggtta
     8581 cttagttatg actgcaacga tcaaagcttt ggtaaaactt tttatggcag aaggatctgc
     8641 aattgatact ggagttattg gagcattagt tgtcggaata gttgccgtat atttgcacaa
     8701 ccgatataac aatattcaat taccttccgc tttaggattc tttggaggtt cacgcttcgt
     8761 tcctattgtt acatcgttct cttctatctt gattggcttt gtcttctttg ttatttggcc
     8821 acctttccaa caacttcttg tttctacagg tggatatatt tctcaggcgg gtccaattgg
     8881 aacttttcta tatggatttt taatgagact ttctggagca gtaggcttac atcatataat
     8941 ttaccctatg ttttggtata ctgaacttgg tggtgttgaa actgttgcag gacaaacagt
     9001 ggttggagct caaaaaatat tttttgctca attagccgat ccggcccatt ctggattatt
     9061 tacagaagga acaaggtttt ttgcaggtcg tttctcaaca atgatgttcg gtttaccggc
     9121 tgcctgttta gcgatgtacc atagtgttcc taaaaatcgt cgtaaaaaat acgcgggttt
     9181 gttttttgga gttgctttaa catcttttat taccggtatt acagaaccaa ttgaatttat
     9241 gtttctattc gtcagtccgg ttctatatgt tgttcacgca ttccttgatg gtgttagctt
     9301 ctttattgca gacgtcttaa atatttcaat aggaaacaca ttttcaggag gtgtaatcga
     9361 tttcacttta tttggaattt tgcaggggaa cgctaagacg aattgggttc ttcagattcc
     9421 aattggactt atttggagtg ttttgtatta tattattttt agatggttca ttactcaatt
     9481 caacgttcta acgccaggac gaggagaaga agtagattct aaagaaattt ctgaatccgc
     9541 agattcaact tcaaatactg cagattattt aaaacaggat agcctacaaa ttatcagagc
     9601 cttgggtgga tcaaataata tagaagatgt agatgcttgt gtgacacgtt tacgtgtagc
     9661 tgtaaaagaa gttaatcaag ttgataaagc acttttaaaa caaattggtg cagttgatgt
     9721 cttagaagtg aagggtggca ttcaagcaat ctatggagca aaagcaatct tatataaaaa
     9781 tagtattaat gaaattttag gtgtagatga ttaagtactt actgacttaa taaaaaacag
     9841 aggagagtga tggatgagta ggatgaaatg aaatcgtata caagaaataa agaactcatt
     9901 atccaagttg gatacgctta ttacatagga gaatacaaat gaaatttaga aaattagctt
     9961 gtacagtact tgcgggtgct gtggttcttg gtcttgctgc ttgtggcaat tctggcggaa
    10021 gtaaagatgc tgccaaatca ggtggtgacg gtgccaaaac agaaatcact tggtgggcat
    10081 tcccagtatt tacccaagaa aaaactggtg acggtgttgg aacttatgaa aaatcaatca
    10141 tcgaagcgtt tgaaaaagca aacccagata taaaagtgaa attggaaacc atcgacttca
    10201 agtcaggtcc tgaaaaaatc acaacagcca tcgaagcagg aacagctcca gacgtactct
    10261 ttgatgcacc aggacgtatc atccaatacg gtaaaaacgg taaattggct gagttgaacg
    10321 acctcttcac agatgaattt gttaaagatg tcaacaatga aaacatcgta caagcaagta
    10381 aagctggaga caaggcttat atgtatccga ttagttctgc cccattctac atggcaatga
    10441 acaagaaaat gttagaagat gctggagtag caaaccttgt aaaagaaggt tggacaactg
    10501 atgattttga aaaagtattg aaagcactta aagacaaggg ttacacacca ggttcattgt
    10561 tcagttctgg tcaaggggga gaccaaggaa cacgtgcctt tatctctaac ctttatagcg
    10621 gttctgtaac agatgaaaaa gttagcaaat atacaactga tgatcctaaa ttcgtcaaag
    10681 gtcttgaaaa agcaactagc tggattaaag acaatttgat caataatggt tcacaatttg
    10741 acggtggggc agatatccaa aactttgcca acggtcaaac atcttacaca atcctttggg
    10801 caccagctca aaatggtatc caagctaaac ttttagaagc aagtaaggta gaagtggtag
    10861 aagtaccatt cccatcagac gaaggtaagc cagctcttga ataccttgta aacgggtttg
    10921 cagtattcaa caataaagac gacaagaaag tcgctgcatc taagaaattc atccagttta
    10981 tcgcagatga caaggagtgg ggacctaaag acgtagttcg tacaggtgct ttcccagtcc
    11041 gtacttcatt tggaaaactt tatgaagaca aacgcatgga aacaatcagc ggctggactc
    11101 aatactactc accatactac aacactattg atggatttgc tgaaatgaga acactttggt
    11161 tcccaatgtt gcaatctgta tcaaatggtg acgaaaaacc agcagatgct ttgaaagcct
    11221 tcactgaaaa agcgaacgaa acaatcaaaa aagctatgaa acaatagtcc ttagttattc
    11281 tataaaaagt agttttttaa agaacctaag agtgtatacc cccttttccc tctacacaga
    11341 tagtgtaaga aaagggggct tttgtttaaa atgtaagaaa ctgtcacgaa attaaaatga
    11401 agttcttaca taagcgaatc ataaaaaatt tcattttgat tttaaaacag ttcaagaaag
    11461 tcaaaaaatt attctatttg aaagagaggt gccgactgtg aaagtcaata aaatccgtat
    11521 gcgggaaaca gtgatttcct acgctttcct agcaccagta ttattcttct ttgtcatctt
    11581 tgtgttggct ccgatggtga tgggcttcat tacaagtttc tttaactact caatgactaa
    11641 atttgagttt gtaggcttgg ataactatat ccgtatgttt aaagatcctg tctttacaaa
    11701 atctctgatt aacacagtta ttttggttat tggatctgta ccagttgttg ttctattctc
    11761 actctttgta gcatctcaga cctatcatca aaatgtcatt gccagatcct tctaccgttt
    11821 cgtcttcttc cttcctgttg taacgggtag tgttgccgtg acagttgttt ggaaatggat
    11881 ttatgaccca ctatcaggga ttctaaactt tgtccttaag tcaagccaca tcatcagcca
    11941 aaacatttct tggttgggag ataaaaactg ggcattgatg gcgattatga ttattctctt
    12001 gaccacttca gttggtcagc ccatcatcct ttatatcgct gccatgggga atattgacaa
    12061 ttcactggtt gaagcggcgc gtgttgatgg tgcaactgag tttcaagttt tttggaagat
    12121 taaatggcca agccttcttc caacaactct ttatattgca atcatcacaa caattaactc
    12181 attccagtgt ttcgccttga ttcagctttt gacatctggt ggtccaaact actcaacaag
    12241 taccttgatg tactaccttt acgaaaaagc cttccaattg acagaatacg gctatgccaa
    12301 cacaattggt gtcttcttgg cagtcatgat tgctatcgta agctttgttc aatttaaagt
    12361 acttggaaac gacgtagaat actaaagaaa ggagacagct atgcaatcta cagaaaaaaa
    12421 accattaaca gcctttactg ttatttcaac aatcattttg ctcttgttga ctgtgctgtt
    12481 catctttcca ttctactgga ttttgacagg ggcattcaaa tcacaacctg atacaattgt
    12541 tattcctcct cagtggttcc ctaaaatgcc aaccatggaa aacttccaac aactcatggt
    12601 gcagaaccct gccttgcaat ggatgtggaa ctcagtattt atctcattgg taaccatgtt
    12661 cttagtctgt gcaacctcat ctctagcagg ttatgtattg gctaaaaaac gtttctatgg
    12721 tcaacgcatt ctatttgcta tctttatcgc tgctatggca cttccaaaac aagttgtcct
    12781 tgtaccattg gtacgtatcg tcaacttcat gggaatccac gatactctct gggcagttat
    12841 cttgcctttg attggatggc cattcggtgt cttcctcatg aaacagttca gtgaaaatat
    12901 ccctacagag ttgcttgaat cagctaaaat cgacggttgt ggtgagattc gtaccttctg
    12961 gagtgtagcc ttcccgattg tgaaaccagg gtttgcagcc cttgcaatct ttaccttcat
    13021 caatacttgg aatgactact tcatgcaatt ggtaatgttg acttcacgta acaatttgac
    13081 catctcactt ggggttgcga ccatgcaggc tgaaatggca accaactatg gtttgattat
    13141 ggcaggagct gcccttgctg ctgttccaat cgtcacagtc ttcctagtct tccaaaaatc
    13201 cttcacacag ggtattacta tgggagcggt caaaggataa tactctgcga aaatcgaatg
    13261 caaactacgt cagcttcacc ttgccatact taagtattgc ctgtggttag cttcctagtt
    13321 tgttcttcaa ttttcattga gtataggaaa atcaatctat caagatacag aagtatattt
    13381 tatagattta gagaatatag aagttataag tgtctacaaa atggagggta tgcagttact
    13441 ttatgaagtt ttgtcagaca cttatcaact taagaatggt tttagttaac tatcagaaac
    13501 gaaggaaaga gtatgatttt tgacgatttg aaaaacatca ccttttacaa agggattcat
    13561 cccaatttag acaaggctat cgactacctc taccaacatc gtaaagattc attcgaatta
    13621 ggaaagtatg agattgatgg agataaagtc tttctagttg ttcaggaaaa tgtcctcaat
    13681 caagttgaga ataatcaatt tgaacaccat aagaactatg cagatttgca tttgctgata
    13741 gaagggcatg aatattcgag ctacggttca cgtatcaaag acgaggcagt agcattcgac
    13801 gaagcgagtg acattggctt tgttcattgt tatgaacact acccactctt attgggttat
    13861 cacaattttg cgattttctt cccaggtgag ccacatcagc caaatggtta tgcaggcatg
    13921 gaagaaaagg ttcgaaaata tctctttaaa atcttgattg attaaaaata ggatgaattg
    13981 tttttttgta aagctttgat aatactctac catgaaattg atctttgtga ggtagagaaa
    14041 tgagaataaa atatttaaaa attggtatct tctaagtatg ctgcaagagc tagtttcttg
    14101 gatggacagg gaattacagt tgatgagatg gcttggataa ttaggggcat tgtgaatgca
    14161 ttgattggta gatacataaa attaggtgct tatgcggcta agtatggtat tagtatggca
    14221 cgctcgatct taagtagggc agctgcaact gcagcagcaa gagtaggatt atcgaccaag
    14281 atttctggat ggattttacg agtagctgtg aatgtagctg atgtatatgg taattttgcc
    14341 tacaatattg ctgcagcttg ggatgcacat gataaaatcc ctaacaatgg tcgtataaac
    14401 ttttaaaatg cgagaatgaa agcactttgt atttttttat tgaatatgtt agcttggaca
    14461 gtgcttgcaa tgataattcg tggagggcta gatggattta atgagcatac ttggagtact
    14521 attttaattg cttcgctgtt cggggtatat gattataagc ccatagataa aaatagaaaa
    14581 aagtccaaaa gaaaaaagaa aaaatagatt tgttcatggt agggacttat gaaagcttta
    14641 ctgacaaaaa agaaaacagt ttacaaagaa aaatgatgga ggagcaaaca tggcacaaaa
    14701 aggagtaagc cttatcaagg cagcatttga tacagacaac tttctcatgc gttttagtga
    14761 gaaagtcttg gacatcgtga cagccaatct tctttttgtc gtctcttgtt tgcccatcgt
    14821 gacgattgga gtggctaaaa tcagcctcta cgagaccatg ttcgaagtta agaagagcag
    14881 acgggtgcct gtttttaaaa tctatctaag atctttcaag caaaatctga aactaggtct
    14941 tcagctgggt ttaatggagt taggaattgt gtttcttacc ctttcagatc tctatctttt
    15001 ctggggtcaa acagctctgc ccttccaatt gctgaaagcc atttgtttag gtattctgat
    15061 ttttcttact atcgtgatgc tggctagtta ccctatcgcg gcacgttatg acctatcttg
    15121 gaaagaaatt cttcaaaaag gattgatgtt ggctagtttt aactttcctt ggttcttcct
    15181 catgttagcc attcttgtcc tcattgtgat ggttctttat ctgtccgcct tcagtctact
    15241 cttaggtggc tcagtcttcc tactttttgg gtttggacta ttggtcttta tccagactgg
    15301 attgatggag aaaattttcg caaaatacca ataggagctt tatttctgaa actactttca
    15361 aaggctccaa acgctattct ataagcgaga aactaaaatc taagtgtcta taagatattg
    15421 aaagcctttt cgggaaagtg tatactaaag aagtaaagaa aaatctgctt tagcagaaaa
    15481 taaaaataat aggagaaaat ctatgtcaga tttgaaaaaa tacgaaggtg tcattccagc
    15541 cttctacgca tgttatgatg atcaaggaga agtaagccca gaacgtacgc gtgccttggt
    15601 tcaatacttc attgataaag gtgttcaagg tctttatgtc aatggttctt ctggtgaatg
    15661 tatctaccaa agcgttgaag atcgcaagtt gattttggaa gaagtcatgg cggtagccaa
    15721 aggtaaattg accatcattg ctcatgttgc ctgcaacaat actaaagaca gtatggaact
    15781 tgctcgccat gctgaaagct tgggagtaga tgctattgca acgattccac caatttactt
    15841 ccgcttgcca gaatactcag ttgccaaata ctggaacgat atcagttctg cagctccaaa
    15901 cacagactac gtgatttaca acattcctca attggcaggg gttgctttga ctccaagcct
    15961 ttacacagaa atgttgaaaa atcctcgtgt tatcggtgtt aagaactctt ctatgccagt
    16021 tcaagatatc caaacctttg tcagccttgg tggggaagac catatcgtct ttaacggtcc
    16081 agatgaacag ttcctaggtg gccgcctcat gggtgctaag gctggtatcg gtggtactta
    16141 tggtgctatg ccagaactct tcttgaaact caatcagttg attgcggata aggacctaga
    16201 aacagcgcgt gaattgcagt atgctatcaa cgcaatcatt ggtaaactca cttctgctca
    16261 tggaaatatg tacggtgtca ttaaagaagt tttgaaaatc aatgaaggct tgaatattgg
    16321 atctgttcgt tcaccattga caccagtgac tgaagaagat cgtccagttg tagaagcggc
    16381 tgctgccttg attcgtgaaa ccaaggagcg cttcctctaa tctaaaagga ggtatttatg
    16441 acatactacg ttgcaattga tatcggtgga accaacatca agtatggttt ggttgatcaa
    16501 gaggggcaac ttcttgaatc gcatgaaatg ccaactgagg cgcataaggg tggacctcat
    16561 atcttacaaa agaccaaaga tatcgtagct agttatttag aaaaaggcct agtagcaggt
    16621 gttgccatat cttctgctgg gatggtggat ccggataagg gtgagatttt ctatgctggg
    16681 ccgcaaatcc ctaactacgc aggcacccag ttcaaaaagg aaatcgaaga aagctttact
    16741 attccttgtg agattgaaaa tgatgtcaac tgtgcaggtc ttgctgaggc agtatctggt
    16801 tcaggcaagg gagcaagtat gacactttgc ttgaccattg gaacaggtat cggtggttgc
    16861 ttgattatgg ataggaaagt cttccatggt tttagcaatt cagcctgtga agtcgggtat
    16921 atgcatatgc aggatggagc ttttcaagac ttggcttcta caacagcttt agtgaaatat
    16981 gtagctgaag cccatggaga agatgttgat cagtggaatg gccgtagaat tttcaaagaa
    17041 gccactgaag gaaacaaaat ctgcatggaa ggtattgacc gtatggttga ctatctagga
    17101 aaaggtctgg caaatatttg ctacgttgcc aatccagaag tggttattct tggtggtggt
    17161 atcatggggc aagaggctat cctcaaacct aagattcgca cagccttgaa agaggctttg
    17221 gtaccaagtt tagcagaaaa aacacgatta gaatttgccc atcaccaaaa tacagcaggg
    17281 atgttgggtg catattatca ttttaagaca aaacaatcct agtttggctc agccaaacta
    17341 ggattttctt acacgttttt gtctacgata gccgttgagt tttttatttt cccagtagct
    17401 attaaagatt ttttccttgc tttcgcgatt gatttccaaa aagtaggcat aaatcaaatc
    17461 gataaagaag agcataggaa gttgagcgga tattcgttgg atataggagg gttggctgtg
    17521 ggtggctaca agaacagtct ctgtataggt ctggctattt ttattgggaa cacttgtaaa
    17581 gagtacagtc tttgccccca tctccttggc atctaataga ctatctaaaa tagaaggagt
    17641 tgagcctgaa agtgagaagc ccagtactag acaattttca tccatgatgc tggttgtcca
    17701 ggcaaagccg tcttggtctg tcaaagcttc gcagaccacg cctagtcgca taaaacgtaa
    17761 tttcatttca cgggcgacga gaccagaact ccctgttcca aagaagtaga tacgctcagc
    17821 atcttcgatt agctgggcaa ttcgttctag ttggatttcg tcaatcaagt cttgtgtttg
    17881 ttccctcata ttgctataac ttctgaggac tcgtttggtc agtggactgt gcttggagac
    17941 ttggttggct tgattttctg cctgatgttg gtattggaaa ataaattctc ggtagccagt
    18001 aaagccacac tttttagcaa agcgggtcaa agcagcttga gaaatatgta atttttgggt
    18061 gacttgttga gaagataaat catctgtaat cgtttcagct tgcaaaaaat agcgagcgat
    18121 ttcttgctct aggtctgtca tttcttcaaa atgtgaatca atgatagttg cgatatctgg
    18181 tttgtccata gggaaagctc ctttacatga gtcatactgg aagactagat cagggaatag
    18241 tcacacttca ttataacaca taatataagg atagataaat aaaaacgcat ttctgtttta
    18301 aaaacgaaaa aatcgaaaaa gcttctctct tttccataat tttctactca aattgtggta
    18361 caattaagag taagatttta agttagaaat gagactgatt tgtatgagaa aatttaacag
    18421 ccattcgatt ccgattcggc ttaatttatt gttttcaatc gtcattttac tctttatgac
    18481 cattattggt cgtttgttgt atatgcaggt tttgaacaag gatttttacg aaaaaaagct
    18541 agcctcagct agtcagacca agattacaag cagttcagcc cgtggggaaa tttatgatgc
    18601 tagtggaaaa cctttggtag aaaatacgtt aaagcaggtt gtttccttta cgcgtagcaa
    18661 taaaatgacg gctacagact taaaagaaac agctaaaaag ttactgactt atgtgagcat
    18721 cagttctcca aatttgacag aacgccagct ggcggattac tatttggctg atcctgaaat
    18781 ctataaaaaa acagtggaag ctctcccaag cgagaaacgc ttggattcag atggaaatcg
    18841 tctatccgaa tcagaactgt ataacaatgc ggtcgatagt gtccaaacaa gtcaactaaa
    18901 ctatacagag gatgaaaaga aagaaatcta tctttttagt cagttaaatg ctgttggaaa
    18961 ctttgcgaca ggaaccattg ctacagatcc tctaaatgat tctcaggtgg ctgttattgc
    19021 ctctatttca aaggagatgc ctggcattag tatttctact tcttgggata gaaaggtttt
    19081 ggaaacttcc ctttcttcta tagttgggag tgtatccagt gaaaaagctg gtctcccagc
    19141 ggaagaagca gaagcctatc ttaaaaaagg ctattctcta aatgaccgtg taggaacctc
    19201 ctatttggaa aagcaatatg aagagacctt acaaggaaaa cgatcggtaa aagaaatcca
    19261 tctggataaa tatggcaata tggaaagcgt ggatacaatt gaggaaggta gtaagggaaa
    19321 caatatcaaa ctgaccattg atttggcctt ccaagatagc gtggatgctt tgctgaaaag
    19381 ttatttcaat tctgagctag aaaatggtgg agccaagtat tctgaaggtg tctatgcagt
    19441 cgcccttaac ccaaaaacag gtgcggtttt gtctatgtca gggattaaac atgacttgaa
    19501 aacaggagag ttgacgcctg attccttggg aacggtaacc aatgtctttg ttccaggttc
    19561 ggttgtcaag gcggcgacca tcagctcagg ttgggaaaat ggagtcttgt caggaaacca
    19621 gaccttgaca gaccagtcca ttgtcttcca aggttcagct cccatcaatt cttggtatac
    19681 tcaggcttac ggttcattcc ctatcacagc ggtccaagct ctggagtatt catcaaatac
    19741 ctatatggtc caaacagcct taggtcttat ggggcaaacc tatcaaccca atatgtttgt
    19801 cggcaccagc aatctagagt ctgctatgga gaaactgcgt tcaacctttg gcgaatatgg
    19861 cttgggtact gcgacaggaa ttgacctacc agatgaatct actggatttg ttcccaaaga
    19921 gtatagcttt gctaattaca ttactaatgc ctttgggcag tttgataact atacgccgat
    19981 gcagttggct cagtatgtag caactattgc aaatgatggt gttcgtgtgg ctcctcgtat
    20041 tgttgaaggc atttatggta ataatgataa gggaggactg ggtgacttga ttcagcaact
    20101 gcaaccgaca gagatgaata aggtcaatat atccgactcc gatatgagca tcttgcacca
    20161 aggtttttat caggttgccc atggtactag tgaattgaca actggacgtg ccttttcaaa
    20221 tggtgccttg gtatccatta gcggaaaaac aggtacagcc gaaagctatg tggcagatgg
    20281 tcagcaagca accaatacca atgcggtggc ctatgcccca tctgataatc cccaaatcgc
    20341 tgtcgcagtg gtctttcctc ataataccaa tctaacaaat ggtgtaggac cttccattgc
    20401 acgtgacatt atcaatctgt atcaaaaata ccatccaatg aactagaaag gaaattatgc
    20461 tttatccaac acctattgcc aagttgattg acagttattc taagttacca ggtatcggga
    20521 ttaagacggc tacgcgtctg gccttttata cgattgggat gtctgctgat gatgtcaatg
    20581 aatttgcaaa aaatctcctt tctgctaaga gagaattgac atattgttct atttgtggac
    20641 gtttgacaga cgacgatcct tgttctatct gtactgatcc gactcgtgac cagacaacaa
    20701 ttttagttct tgaggatagt agagatgtgg cagccatgga aaatatccaa gaataccatg
    20761 gactctatca tgtccttcat ggcctcattt ctcctatgaa tggtatcagt ccggacgata
    20821 tcaatctcaa gagccttatg actcgtctta tggatagtga ggtttcagaa gtgattgtgg
    20881 cgactaatgc tacagcggat ggtgaagcga cttccatgta tctttcacgt ttgctcaagc
    20941 cggctggtat caaggttacg cgtctagcac gaggtctcgc tgtgggagcg gacattgagt
    21001 atgcggacga agtgacactc ttacgagcca ttgaaaatcg gacagagttg taagtgtagg
    21061 caaatttacg aactccattc atttataaaa aatcaaagag gctggaaatc gttcctatcg
    21121 gcctcttttt gtatagtgtg atgagtagga tcaggttcaa gttttaaaaa accaagcaaa
    21181 tatgatatac taaagagcga gtattctagt agaattagga caaataatat gaaacaaacg
    21241 attattcttt tatatggtgg acggagtgcg gaacgcgaag tctctgtcct ttcagctgag
    21301 agtgtcatgc gtgcggtcga ttacgaccgc ttcacagtca agactttctt tatcagtcag
    21361 tcaggtgact ttatcaaaac acaggaattt agtcatgctc cggggcaaga agaccgtctc
    21421 atgaccaatg aaaccattga ttgggataag aaagttgcac caagtgctat ctacgaagaa
    21481 ggtgcagtgg tctttccagt ccttcacggg ccaatgggag aagatggctc tgttcaagga
    21541 ttcttggaag ttttgaaaat gccttacgtt ggttgcaaca ttttgtcatc aagtcttgcc
    21601 atggataaaa tcacgactaa gcgtgttctg gaatctgctg gtattgccca agttccttat
    21661 gtggctatcg ttgaaggcga tgatgtgact gctaaaatcg ctgaagtgga agaaaaattg
    21721 gcttatccag tcttcactaa gccgtcaaac atggggtcta gtgtcggtat ttctaagtct
    21781 gaaaaccaag aagaactccg tcaagcctta gaacttgcct tccgatatga tagccgtgtc
    21841 ttggttgagc aaggagtgaa tgcccgtgaa attgaggttg gcctcttggg taactacgat
    21901 gtcaagagca cgctaccagg agaagttgtc aaggacgttg ccttttatga ctacgatgcc
    21961 aagtatattg ataacaagat tactatggat attcctgcca aaatcagtga tgatgtggtg
    22021 gctgtcatgc gtcaaaatgc agaaacagcc ttccgtgcca ttggtggcct tggtctatct
    22081 cgttgcgatt tcttctatac agataaggga gagatttttc tcaacgagct caataccatg
    22141 ccaggtttca cccagtggtc tatgtaccca ctactttggg acaatatggg gatcagctac
    22201 ccagaactaa tcgagcgttt ggttgacctt gccaaggaaa gttttgacaa gcgcgaagcg
    22261 catttgatat aaaatgaaag agagggtaga agccagaacc atcactgcaa ggtgactaga
    22321 gttctcggac ttcagccctt tttaaaggag tagaaatgaa attaacaatc catgaaattg
    22381 cccaagttgt tggagccaaa aatgatatca gtatctttga ggacacccag ttagaaaaag
    22441 ctgagtttga tagtcgtttg attggaactg gagatttatt tgtgccactt aaaggtgcgc
    22501 gtgatggcca tgactttatt gaaacagcct ttgaaaatgg tgcagcagta accttgtctg
    22561 agaaagaggt ctcaaatcat ccttacattc tagtagatga tgttttgaca gcctttcaat
    22621 ccctagcatc ctactatctt gaaaaaacga ctgttgatgt ctttgctgtt acaggttcaa
    22681 atggcaagac aacgactaag gatatgttgg cgcatttact gtcaacaaga tacaagacct
    22741 acaaaacaca aggcaattac aataacgaga ttggccttcc ttacacagtt cttcatatgc
    22801 ctgaagggac agaaaagttg gtcttggaga tggggcagga tcacttggga gatattcatc
    22861 tcttgtctga actggctcgt ccaaaaacag ccatcgtgac cttggttgga gaagctcatt
    22921 tggccttttt caaagatcgt tctgagattg ctaaaggaaa aatgcaaatt gcggacggaa
    22981 tggcttcagg ttccttgctt ttagcgccgg ctgaccctat cgtagaggac tatttgccaa
    23041 ctgataaaaa agtggttcgt tttgggcaag gggcagagct ggaaattact gacttggttg
    23101 agcgcaaaga tagtctgacc ttcaaggcca atttcttaga gcaagccctt gatttgccag
    23161 taactggtaa gtacaatgct accaatgcta tgattgcatc ctatgttgcc ctacaagaag
    23221 gagtttcaga ggagcaaatc cgtttggcct tccaaggtct tgaattgacg cgtaatcgta
    23281 ctgagtggaa gaaagcagcc aatggagcag atatcctgtc agacgtatat aatgccaatc
    23341 caactgctat gaagctgatt ttagagactt tctctgccat tccagccaat gaaggtggca
    23401 agaaaattgc agtgttggcg gatatgaagg agcttggtga ccagtctatt caactccata
    23461 accagatgat tttgagcctt tcgccagatg tgcttgatac cgttattttc tatggagaag
    23521 acattgctga attagcccaa ttggccagtc aaatgttccc aattggccac gtttactact
    23581 tcaagaaaac agaagaccaa gaccaatttg aagacctagt caagcaggtc aaggaaagcc
    23641 tcagtgccaa tgatcaaatc ttgctcaagg gctctaactc tatgaaccta gccatgttgg
    23701 tagaaagttt agaaaatgaa accaagtgat tttgttaagt atctgcaaag aatgattgcc
    23761 cttacagata ctggcttaac ctttacaaaa gatccttttg accgtgagcg ctacgaggac
    23821 ttgcgaagtc tgttatctga aatgttgaat cagggatcag acctggatgc agaagaagta
    23881 gcagaagtct tgaaaccaac ttcagcttat gcgactccct taatggacgt ccgtgcttgg
    23941 attgttgagg atgagaagat ttgtctggtt aggggacaag gagaggatag ttgggctttg
    24001 ccaggtggct ttggtgaagt cggctattct ccaactgaaa atattctcaa ggaaattgaa
    24061 gaagaaaccg gttttaaagc caaagttgaa agactgctag ctgtttttga taccaatcgt
    24121 ttccaactac agagcaaaca atatgcaaag tttgtttttg aatgtaagct tctcgatgga
    24181 caattccaag aaaatcaaga aatcgctgac cttcaatttt ttgcaattga ccaactgccg
    24241 aatttatctg aaaaacgcat taccaaggag caaatagagc ttctttggca ggtttatcaa
    24301 ggtcagaggg agcaatatct tgactaagaa gatgattatc gtatttctaa attcattttt
    24361 cttaagtagc atggtataat aaaatgcagg aaaattttga atcatgagga agactagatg
    24421 aatttatggg atattttctt tacgactcag gcaaccgagc cgcccaaatt tgaccttttt
    24481 tggtatgtta gcctatttac gctcttagcc ttaacctttt atacagccca tcgctatcgt
    24541 gaaaagaagg tttaccaacg atttttccaa atcttgcaga ctgttcagtt aatccttctt
    24601 tatggttggt actgggtcaa tcatatgcca ctgtcagaaa gcctaccctt ttaccattgc
    24661 cgtatggcta tgtttgtggt actcttgctt cctggtcagt ccaaatataa acaatacttt
    24721 gcattattgg gaacatttgg gacattagca gcctttgttt atccagtgcc agatgcttac
    24781 ccttttccac atatcaccat tctatccttt atctttggtc atttagcact cttggggaac
    24841 tctctagttt atctattgag acagtataat gcgcgattgc tggatgtgaa gggaattttt
    24901 ctcatgacct ttgccctaaa tgccttgatt tttgtggtca atttggtgac aggtggcgat
    24961 tacggatttt tgacaaaacc gccattggtt ggggatcacg gtctagtagc taattattta
    25021 cttgtttcaa ttgtgctggt agctactatc agtttgacta agaaaatctt agaattcttt
    25081 ttagctcaag aagcagaaaa aatgattgca aaggaagctt aacacagagc tttctttttt
    25141 gctcttagag agtttttaca agcagcttat aaaataagaa tttctgaata gacaaactca
    25201 aaaaatggct gggaaattta ggaaaaaagc aagcacgatt aaattttttg tgttataata
    25261 ttttgtgaat agctatgcct atgtttagct atggaataat acgaagtgcg aaacttggaa
    25321 gatagagagg aagcgatgta atggctagag aaggcttttt tacaggtcta gatattggaa
    25381 caagctctgt caaggtgctt gtggccgagc agagaactgg tgaattaaat gtaattggcg
    25441 tgagtaatgc caaaagtaaa ggtgtaaagg atggaattat tgttgatatt gatgcagcag
    25501 caactgctat caagtcagcc atttcccaag cggaagaaaa ggcaggcatt tcgattaaat
    25561 cagtaaatgt cggcttgcct ggtaatcttt tgcaggtaga accaactcag gggatgattc
    25621 cagtaacatc tgatactaag gaaattacgg atcaagatgt tgaaaatgtt gtcaaatcag
    25681 ctttgacaaa gagtatgaca cctgaccgtg aagtcattac ctttattcct gaagaattta
    25741 ttgtggatgg tttccaaggg attcgtgacc cacgtggcat gatgggggtt cgccttgaaa
    25801 tgcgtggttt gctttataca ggacctcgta ctatcttgca caatttgcgt aagacggttg
    25861 agcgtgcagg tgttcaggtt gaaaatgtta tcatttcacc actagcaatg gttcagtctg
    25921 ttttgaacga aggggaacgt gaatttggtg ctacagtgat tgatatgggg gcaggtcaaa
    25981 cgactgtcgc tacaatccgt aatcaagaac tccagttcac acatattctc caagaaggtg
    26041 gagattatgt aactaaagat atctccaagg ttttgaaaac ctctcgcaaa ttagcggaag
    26101 gcttgaaact gaattacggg gaagcctatc cgcctcttgc aagcaaagaa accttccaag
    26161 tagaggttat tggagaagta gaagcagtcg aagtgacgga agcctacttg tcagaaatta
    26221 tttctgcacg aatcaagcac atccttgaac aaatcaagca agaattagat agaaggcgtc
    26281 tattggacct ccctggtggt attgtcttaa tcggtgggaa tgccatttta ccaggtatgg
    26341 ttgagcttgc tcaggaagtc tttggcgtcc gtgtcaagct ttatgttcca aatcaagttg
    26401 gtatccgtaa tccagccttt gcgcatgtga ttagtttatc agaatttgcg ggtcaattaa
    26461 cagaagttaa tcttttggct cagggagcga taaaaggtga gaatgactta agtcatcagc
    26521 caattagttt tggtgggatg ctgcaaaaaa cagctcagtt tgtacaatca acgcctgttc
    26581 aaccagctcc tgctccagaa gtagagccgg tggcgcctac agaaccaatg gcggatttcc
    26641 aacaagcttc acaaaataaa ccgaaattag cagatcgttt ccgtggcttg atcggaagca
    26701 tgtttgacga ataaagagga aaaataaatt atgacatttt catttgatac agctgctgct
    26761 caaggggcag tgattaaagt aattggtgtc ggtggaggtg gtggcaatgc catcaaccgt
    26821 atggtcgacg aaggtgttac aggcgtagaa tttatcgcag caaacacaga tgtacaagca
    26881 ttgagtagta caaaagctga gactgttatt cagttgggac ctaaattgac tcgtggtttg
    26941 ggtgcaggag gtcaacctga ggttggtcgt aaagccgctg aagaaagcga agaaacactg
    27001 acggaagcta ttagtggtgc cgatatggtc ttcatcactg ctggtatggg aggaggctct
    27061 ggaactggag ctgctcctgt tattgctcgt atcgccaaag atttaggtgc gcttacagtt
    27121 ggtgttgtaa cacgtccctt tggttttgaa ggaagtaagc gtggacaatt tgctgtagaa
    27181 ggaatcaatc aacttcgtga gcatgtagac actctattga ttatctcaaa caacaatttg
    27241 cttgaaattg ttgataagaa aacaccgctt ttggaggctc ttagcgaagc ggataacgtt
    27301 cttcgtcaag gtgttcaagg gattaccgat ttgattacca atccaggatt gattaacctt
    27361 gactttgccg atgtgaaaac ggtaatggca aacaaaggga atgctcttat gggtattggt
    27421 atcggtagtg gagaagaacg tgtggtagaa gcggcacgta aggcaatcta ttcaccactt
    27481 cttgaaacaa ctattgacgg tgctgaggat gttatcgtca acgttactgg tggtcttgac
    27541 ttaaccttga ttgaggcaga agaggcttca caaattgtga accaggcagc aggtcaagga
    27601 gtgaacatct ggctcggtac ttcaattgat gaaagtatgc gtgatgaaat tcgtgtaaca
    27661 gttgtcgcaa cgggtgttcg tcaagaccgc gtagaaaagg ttgtggctcc acaagctaga
    27721 tctgctacta actaccgtga gacagtgaaa ccagctcatt cacatggctt tgatcgtcat
    27781 tttgatatgg cagaaacagc tgaattgcca aaacaaaatc cacgtcgttt ggaaccaact
    27841 caggcatctg cttttggtga ttgggatctt cgccgtgaat cgattgttcg tacaacagat
    27901 tcagtcgttt ctccagtcga gcgctttgaa gccccaattt cacaagatga agatgaattg
    27961 gatacacctc catttttcaa aaatcgttaa gtaaatgaat gtaaaagaaa atacagaact
    28021 tgtttttcga gaagttgcag aggctagtct gagtgctcat cgagagagtg gttcggtctc
    28081 tgtcattgca gttaccaagt atgtagatgt accgacagcg gaagccttgc ttccgctagg
    28141 tgttcatcat atcggtgaaa atcgtgtaga taagtttctg gaaaaatatg aagctttaaa
    28201 agatcgagat gtgacttggc atttgattgg taccttgcaa agacgtaagg tgaaagatgt
    28261 cattcaatac gttgattatt tccatgcatt ggactcagta aagctagcag gggaaattca
    28321 aaaaagaagt gaccgagtca tcaagtgttt ccttcaagta aatatttcta aagaagaaag
    28381 caaacacggt ttttcgagag aggaactgct ggaaatcttg ccagagttag ccagactaga
    28441 taagattgaa tatgttggtt taatgacgat ggcacctttt gaggctagca gtgagcagtt
    28501 gaaagagatt ttcaaggcga cccaagattt acaaagagaa attcaagaga aacaaattcc
    28561 aaatatgcct atgaccgagt taagtatggg aatgagtcgt gattataaag aagcgattca
    28621 attcggttcc acttttgttc gtataggtac atcatttttt aagtaggaga gaaccatgtc
    28681 tttaaaagat agattcgata gatttataga ttattttacg gaggatgagg attcaagtct
    28741 cccttatgaa aaaagagatg agcctgtgtt tactccagta aattcttcac aggaaccggc
    28801 tctcccaatg aatcaacctt cacagtcggc tggtacaaaa gagaacaata tcaccagact
    28861 tcatgcaaga caacaggaat tggcaaatca gagtcagcgt gcaacggata aggtcattat
    28921 agatgttcgt tatcctagaa aatatgagga tgcaacagaa attgttgatt tattggcagg
    28981 aaacgaaagt atcttgattg attttcagta tatgacagag gtgcaggctc gtcgttgttt
    29041 ggactatttg gatggagctt gtcatgtttt agctggaaat ttgaaaaagg tagcttctac
    29101 catgtatttg ttgacaccag tgaatgttat tgtaaatgtt gaagatatcc gtttaccaga
    29161 tgaagatcaa cagggtgagt tcggttttga tatgaagcga aatagagtac gataatgatt
    29221 tttttaattc gtatgattta taatgcagtg gatatttact ccctgatttt ggtagccttc
    29281 gctgtcatgt cttggtttcc aggtgcctac gaatccagtt taggtcgttg gattgtagcg
    29341 ttggtgaaac cagtgcttgc tcccttgcaa cgcctgcctt tacagatagc gggtcttgat
    29401 ttatctgttt gggtcgcgat tgttttggtt cgatttttag gagaaaacct agtgcgtttt
    29461 ctggcgatga taggatgaat aaagggattt attagcattt ctccatagaa gatcgtccat
    29521 ttcttgacaa gggaatggaa tggataaaga aggtagaaga tagctatgct ccttttttaa
    29581 ctccttttat caatcctcat caggagaagc tattaaagat tttggccaaa acctatggtc
    29641 ttgcttgtag cagtagtggg gaattcgtct cgagtgagta tgttcgagtt ttattatacc
    29701 cagattattt ccaaccagag ttttcagatt ttgaaatatc tctccaggaa attgtgtatt
    29761 ccaataaatt tgaacattta acgcatgcta agattttagg gacagtcatc aatcaattag
    29821 ggattgaacg gaaacttttt ggagatatcc tagtagatga agaacgggcg cagattatga
    29881 ttaatcagca gtttcttctt ctctttcaag atggactaaa gaaaattggt cgtatacctg
    29941 tttcgctgga ggaacgtcct ttcaccgaga aaatagataa gctagaacag tatcgagaac
    30001 tggatttatc tgtgtctagt tttcgattag atgttctttt atcaaatgtt ttgaaactat
    30061 ctaggaatca agcaaaccag ttgattgaaa agaaacttgt ccaagtaaat tatcatgtgg
    30121 tagacaaatc agattacact gttcaagttg gagacttgat tagtgtgaga aaatttggtc
    30181 gcttgagatt acttcaagat aagggacaaa cgaaaaaaga gaagaaaaaa ataaccgtcc
    30241 agttattatt aagtaagtga ggaatagaat gccaattaca tcattagaaa taaaggacaa
    30301 gacttttgga actcgattca gaggttttga tccagaagaa gtcgatgaat ttttagatat
    30361 tgtggttcgt gattacgaag atcttgtgcg tgcgaatcat gataaaaatt tgcgtattaa
    30421 gagtttagaa gagcgtttgt cttactttga tgaaataaaa gattcattga gccagtctgt
    30481 attgattgct caggatacag ctgagagagt gaaacaggcg gcgcatgaac gttcaaacaa
    30541 tatcattcat caagcagagc aagatgcgca acgcttgttg gaagaagcta aatataaggc
    30601 aaacgagatt cttcgtcaag caactgataa tgctaagaaa gtcgctgttg aaacagaaga
    30661 attgaagaac aagagccgtg tcttccacca acgtctcaaa tctacaattg agagtcagtt
    30721 ggctattgtt gaatcttcag attgggaaga tattctccgt ccaacagcta cttatcttca
    30781 aaccagtgat gaagccttta aagaagtggt tagcgaagta cttggagaac cgattccagt
    30841 tccaattgaa gaagaaccaa ttgatatgac acgtcagttc tctcaagcag aaatggaaga
    30901 attacaagct cgtattgagg tagccgataa agaattgtct gaatttgaag ctcagattaa
    30961 acaggaagtg gaagctccaa ctcctgtagt gagtcctcaa gttgaagaag agcctctgct
    31021 catccagttg gcccaatgta tgaagaacca gaagtagctc cagtgcatcc gacaggtcca
    31081 acaccagcta cagaaactgt tgattcagca ccgggatttg aagcaccgca agaatctgtt
    31141 acaattttat aagaaatatt ctgagaacaa tatcttatcc ttatattccc agcgagcagg
    31201 agatggtgtg agtcctgcat tccctatcga taagattatc ctctcaaaaa ctcaagtctg
    31261 aatctagtaa gatttgacgt tccccacgtt acgggataag agggagaaag actaaaactt
    31321 tttccgaata aaggtggtac cacgattttc gtcctttttg gaagttgtgg tttttaattt
    31381 gttattattt ataaaggaga taccatgaaa ctcaaagaca cccttaatct tgggaaaact
    31441 gaattcccaa tgcgtgcagg ccttcctacc aaagagccag tttggcaaaa ggaatgggaa
    31501 gatgcaaaac tttatcaacg tcgtcaagaa ttgaaccaag gaaaacctca tttcaccttg
    31561 catgatggcc ctccatacgc taacggaaat atccacgttg gacatgctat gaacaagatt
    31621 tcaaaagata ttattgttcg ttctaagtct atgtcaggat tttacgcacc atttattcct
    31681 ggttgggata ctcatggtct gccaatcgag caagtattgt caaaacaagg tgtcaaacgt
    31741 aaagaaatgg acttggttga gtacttgaaa ctttgccgtg agtacgctct ttctcaagta
    31801 gataaacaac gtgaagattt taaacgtttg ggtgtttctg gtgactggga aaatccatat
    31861 gtgaccttga ctcctgacta tgaagcagct caaattcgtg tatttggtga gatggctaat
    31921 aagggttata tctaccgtgg tgccaagcca gtttactggt catggtcatc tgagtcagcc
    31981 cttgctgaag cagagattga ataccatgac ttggtttcaa cttcccttta ctatgccaac
    32041 aaggtaaaag atggcaaagg agttctagat acagatactt atatcgttgt ctggacaacg
    32101 actccattta ccatcacagc ttctcgtggt ttgacggttg gtgcagatat tgattacgtt
    32161 ttggttcaac ctgctggtga agctcgtaag tttgtcgttg ctgctgaatt attgactagc
    32221 ttgtctgaga aatttggctg ggctgatgtt caagttttgg aaacttaccg tggccaagaa
    32281 ctcaaccaca tcgtaacaga acacccatgg gatacagctg tagaagagtt ggtaattctt
    32341 ggtgaccacg ttacgactga ctctggtaca ggtattgttc atacagcccc tggttttggt
    32401 gaggacgatt acaatgttgg tattgctaat aatcttgaag tcgcagtgac tgttgatgaa
    32461 cgtggtatca tgatgaagaa tgctggtcct gaatttgaag gtcaattcta tgaaaaggta
    32521 gttccaactg tgattgaaaa acttggtaac ctccttcttg cccaagaaga aatctctcac
    32581 tcatatccat ttgactggcg tactaagaaa ccaatcatct ggcgtgcagt tccacaatgg
    32641 tttgcctcag tttctaaatt ccgtcaagaa atcttggacg aaattgaaaa agtgaaattc
    32701 cactcagaat ggggtaaagt ccgtctttac aatatgatcc gtgaccgtgg tgactgggtt
    32761 atctctcgtc aacgtgcttg gggtgttcca cttcctatct tctacgctga agatggtaca
    32821 gctatcatgg tagctgaaac tattgaacac gtagctcaac tttttgaaga acatggttca
    32881 agcatttggt gggaacgtga tgccaaagac ctcttgccag aaggatttac tcatccaggt
    32941 tcaccaaacg gcgagttcaa aaaagaaact gatatcatgg acgtttggtt tgactcaggt
    33001 tcatcatgga atggagtggt ggtaaaccgt cctgaattga cttacccagc cgacctttac
    33061 ctagaaggtt ctgaccaata ccgtggttgg tttaactcat cacttatcac atctgttgcc
    33121 aaccatggcg tagcacctta caaacaaatc ttgtcacaag gttttgccct tgatggtaaa
    33181 ggtgagaaga tgtctaaatc tcttggaaat accattgctc caagcgatgt tgaaaaacaa
    33241 ttcggtgctg aaatcttgcg tctctgggta acaagtgttg actcaagcaa tgacgtgcgt
    33301 atctctatgg atattttgag ccaagtttct gaaacttacc gtaagattcg taacactctt
    33361 cgtttcttga ttgccaatac atctgacttt aacccagctc aagatacagt cgcttacgat
    33421 gagcttcgtt cagttgataa gtacatgacg attcgcttta accagcttgt caagatcatt
    33481 cgtgatgcct atgcagactt tgaattcttg acgatctaca aggccttggt gaactttatc
    33541 aacgttgact tgtcagcctt ctaccttgat tttgccaaag atgttgttta cattgaaggt
    33601 gccaaatcac tggaacgccg tcaaatgcag actgtcttct atgacattct tgtcaaaatc
    33661 accaaactct tgacaccaat ccttcctcac actgcggaag aaatttggtc atatcttgag
    33721 tttgaaacag aagacttcgt ccaattgtca gaattaccag aggctcaaac ttttgctaat
    33781 caagaagaaa tcttggatac atgggcagcc ttcatggact tccgtggaca agctcaaaaa
    33841 gccttggaag aagctcgtaa tgcaaaagta atcggtaaat cacttgaagc acacttgaca
    33901 gtttatccaa acgaagttgt gaaaactcta ctcgaagcag taaacagcaa tgtggctcaa
    33961 cttttgatcg tgtcagactt gaccatcgca gaaggaccag ctccagaagc tgcccttagc
    34021 ttcgaagatg tagccttcac agttgaacgc gctgcaggtg aagtatgtga ccgttgccgt
    34081 cgtattgacc caacaacagc agaacgtagc taccaggcag ttatctgtga ccactgtgca
    34141 agtatcgtag aagaaaactt tgcagatgca gtcgcagaag gatttgaaga gaaataagat
    34201 tgaaaagtct aggcaaaatt caatttgaga agaaaagaca actaatttta tagtctatta
    34261 aacgcattgt atcacgtttt tgaacacctg atatgatgcg ttttttattt ttaaaatttg
    34321 caaggtgtga ctttttatac tcatactcaa tgaaaatcaa aaagcaaact aggaagctag
    34381 ccgcaggctg ctcaaaacac tgttttgagg ttgtagataa gactgacgaa gtcagtaaca
    34441 tatatatggt aaggcgacgc tgacgtggtt tgaagagatt ttcgaagagt atcaacaaga
    34501 atcaaagaga aacttagcaa gctaacagta gtaagataaa ataggaattt gatattaggg
    34561 ataagattgg taaatagtgt aatattttta caacaataaa tttatatagt tatttctggt
    34621 ttctgaaaag tattatatta tattttattt catattatac aaatttttat tttataatat
    34681 cagaaaatac tttttttaaa aagcaaatat gatacaattt tatttgaaaa aaaataaaaa
    34741 aggagatttt attatgaaat caagtggtat cgtcggtctt gtgggaggaa ttttacttct
    34801 tatttgtcct tttgtcttgt tgggaacagc ggtaaataca gctgctacaa ctcttaatgg
    34861 aggagctact gcaggggctt tttcaggtgt tgccttactc ttgaatacct tgaagattgc
    34921 aaatcttgtt cttggtatca ttgctattgt ttactataaa ggagataagc atgtaggtgc
    34981 agctccgtct gtactaatga ttgtttctgg tgaagttagt ctcattccat tcttaggatg
    35041 agttgggggg attcttgcta ttatcggagg atctctattc cttgcaacat tgaagaaatt
    35101 caaatcagaa gaataaaagg tattttagca tgaaaagaac aaaaaagttt atcggtatag
    35161 gagtagctct attatctctt tctcttctag ttgcatgtgg aacataaagt tcaaagaata
    35221 cttcaacaag taatgatgag aagacagtag caacatccaa tagttcaaaa gaaacaatca
    35281 ctttcgatac accggttgta acagacgatg cgattgaatc aatacgcact tatgcagatt
    35341 atatagatct ttataaaaat atttttgatg attattttac taaagctgag gaaggtttca
    35401 aaggcacagt tatggaaaat aatgactcgt ttactaaact aaaagagtca actcaaaaat
    35461 tattcgatgc gcagaaaaaa aggttaaata atgaagatag aatagaaaca gccaaaaaca
    35521 atgtgattgc caaacattgt caaacagtcc tttccttttt ggttttgact agcttttttg
    35581 tgaaaaattg tgtaaaatag aatagataaa cgaggggaaa cctcggaaaa tttaaaggag
    35641 aatccatcta atggtaaaat tggtttttgc tcgccacggt gagtctgaat ggaacaaagc
    35701 taaccttttc actggttggg ctgatgttga tttgtctgaa aaaggtacac aacaagcgat
    35761 tgacgctggt aaattgatca aagaagctgg tatcgaattt gaccaagctt acacttcagt
    35821 attgaaacgt gctatcaaaa caactaactt ggctcttgaa gcttctgacc aattgtgggt
    35881 tccagttgaa aaatcatggc gcttgaacga acgtcactac ggtggtttga ctggtaaaaa
    35941 caaagctgaa gctgctgaac aatttggtga tgagcaagtt cacatctggc gtcgttcata
    36001 cgatgtattg cctccaaata tggaccgtga tgatgagcac tcagctcaca cagaccgtcg
    36061 ttatgcttca cttgacgact cagtaatccc agatgctgaa aacttgaaag tgactttgga
    36121 acgtgctctt ccattctggg aagataaaat cgctccagct cttaaagatg gtaaaaacgt
    36181 attcgtagga gctcacggta actcaatccg tgcccttgta aaacacatca aaggtttgtc
    36241 agatgatgag atcatggacg tggaaatccc taacttccca ccattggtat tcgaattcga
    36301 cgaaaaattg aacgttgttt ctgaatacta ccttggaaaa taaaaaattg taagcctagg
    36361 attgatttct aggcttttta tgttagtatg gaagtatgat aaggaataaa aaacaagatt
    36421 atgtactggc ctacaaacaa ccagcttcaa ccacttacat gggttgggaa gaagaagctt
    36481 taccgatagg taatggttct ttaggagcaa aagtatttgg ccgtataggg gctgaacgga
    36541 ttcaatttaa tgaaaaaagt ctctggtctg gaggtccact tcctgatagt tcagattatc
    36601 agggtggaaa tcttcaggat cagtatgttt ttttagctga gattcggcag gctttggaga
    36661 agagagatta caatctggct aaggaactgg ctgagcagca cctaattggg ccaaaaacga
    36721 gtcaatatgg gacctatctg tcttttgggg atattcacat tgagttcagc cagcaaggta
    36781 cgactttgtc tcaggtgacg gactatcaga gacagctgaa tattagtaag gcacttgtga
    36841 cgacttctta tgtctataag ggaacgcgat ttgaacgtga agcttttgcg agttttccag
    36901 atgatctctt ggttcagcgt tttactaagg aaggggcgga aactctagat tttactatag
    36961 aactatcctt gacctgtgat ttggcttctg atgaaaagta tgagcaggaa aaatctgatt
    37021 acaaggagtg taagttggat attactgatt ctcatatctt gatgaaggga agagttaagg
    37081 ataatgatct gcggtttgct agttatctag cttgggaaac ggatggagat attagagttt
    37141 ggtcagatag ggttcagata tcaggagcca gttatgccaa tctcttcttg gccgctaaga
    37201 cggattttgc ccaaaatcct gctagcaatt atcgcaagaa actagattta gagcaacagg
    37261 tgatagactt ggtggacaca gctaaagaaa agggctatac ccaattgaaa tcaaggcata
    37321 tcgaggacta ccaagcctta ttccagcgtg ttcaattgga tttggaagct gatgttgacg
    37381 catccactac agatgatttg ttaaaaaatt ataagccaca agaagggcag gctttggagg
    37441 agctgttctt ccagtatgga cggtatttat tgattagttc gtccagagac tgcccagatg
    37501 ctctaccagc taacctacag ggagtctgga atgcggtcga caatcctcct tggaattcgg
    37561 actatcactt aaatgtcaat ctgcagatga attattggcc agcctatgtt accaatctcc
    37621 tagaggcggt ctttccggtc atcaactatg tagatgattt gcgtgtctat ggtcgtctag
    37681 cggctgtaaa gtatgcagga atcgtctctc agaaaggtga ggaaaatggt tggttggttc
    37741 atactcaagc gactcccttt ggttggacgg cacctggttg ggattactat tggggttggt
    37801 caccagctgc caatgcgtgg atgatgcaaa ccgtttatga agcctattca ttttataggg
    37861 accaagacta tctcagggag aaaatttatc ccatgttgag ggaaacggtt cgtttttgga
    37921 atgccttttt acataaggat cagcaggcgc agcgttgggt gtcttctccg tcttattctc
    37981 cagaacatgg gccgatttcg attggcaata cctatgacca atctctgatt tggcagttat
    38041 ttcatgattt tattcaggct gctcaggaat tgggactgga tgaggacttg ttgactgagg
    38101 ttaaggagaa gtctgattta ctaaatcctt tgcaaatcac tcaatctggt cgaatcaggg
    38161 agtggtatga ggaggaagag cagtattttc aaaatgagaa agtggaggcc cagcaccggc
    38221 acgcttccca tctagtggga ctctatcctg gcaatctctt tagctacaag ggacaagagt
    38281 atattgaagc ggcgcgtgct agcctcaatg atcgtggaga tggcggcaca ggctggtcca
    38341 aggctaataa gatcaatctc tgggcgcgtt tgggagatgg caatcgagcc cataaattat
    38401 tggcagagca gttaaagaca tccaccttgc caaatctttg gtgtagccat cctccttttc
    38461 agatagatgg taattttggt gctactagtg gcatggcaga aatgttactc cagtctcatg
    38521 cagcttatct ggtacctcta gctgccctac ctgatgcttg gtcaacaggt tctgtttcag
    38581 gcttaatggc acgtggacat tttgaagtga gcatgagctg ggaagataaa aaactcttac
    38641 agttgaccat tttatcaagg agtggaggag atttgcgagt ttcttatcca gatattgaga
    38701 agagtgtgat taaaatgaat caagaaaaaa taaaagcgaa atgcatgggg aaagattgta
    38761 tttcggtggc aacagcagaa ggtgatcttg ttcaatttta tttttaagaa gatgttataa
    38821 ggcagtaatt tgaaactgcc ttttaataag gatttaagaa tataagcagt tttcaactag
    38881 ttgaaaaagc gttataatga taataggaag taatactcaa tgaaaatcaa agagcacaaa
    38941 caaggaagct agccgcaggt tgctcaaaac agtgttttga ggttgcagat ggaagctgac
    39001 gtggtttgaa gagagatttt cgaggagtat aatttgtttg atagagggtg ggtctgatgg
    39061 cttatattga gatgaaacac tgttacaagc gttatcaggt tggggacacg gagattgtgg
    39121 ccaatcgtga tgtgaatttt gagattgaaa agggggagct ggttattatc cttggtgctt
    39181 caggtgcagg caagtcaaca gtgcttaacc ttcttggggg aatggatacc aatgatgaag
    39241 gggaaatctg gattgatggt gttaatattg cggattatag ttcccaccag cgcaccaatt
    39301 accgtagaaa tgatgtgggg tttgtttttc agttttataa tctagtttct aatctgacag
    39361 ctaaggaaaa tgtggaactg gcttctgaaa ttgtgacaga tgccttgaat cctgatcagg
    39421 tcttgacaga tgtaggtctg gctcatcgtc taaataactt tccagcccag ctttctggag
    39481 gggagcaaca gcgagtctcc attgcacgcg cggtagccaa aaatcctaaa attcttcttt
    39541 gtgatgaacc tactggagcc ttggattatc agacgggcaa gcaggttttg aaaattctcc
    39601 aagatatgtc tcgtcaaaag ggagcgacgg tgatcatcgt gactcataat ggagctttgg
    39661 cgcccattgc tgatcgcgtg attcatatgc acgatgccag tgtcaaggat gtggtgctca
    39721 accagcatcc tcaggatatt gacagtttgg agtactagta tgatcaagcg aaaaacttat
    39781 tggaaggact taattcagtc cttcacaggc tccaaggggt gttttttatc catcttgatc
    39841 ctgatgatgt tgggatctct agccttagta ggcctcaaag taaccagtcc caacatggag
    39901 gcgacagcta atgcttattt aacaactgct caaaccttgg atttggcagt catgtctaac
    39961 tatggcttgg atcaagcaga ccaagaagaa ctaaaacaga cggagggcgc agaggtcgag
    40021 tttggctatt tgacagatgt gactatggat aatgggcagg atgccattcg gctgtactcc
    40081 aaaccagagc gaatttcaac ctttcagcta agaaagggac gacttcctca gtcagacaag
    40141 gaaatcgctt tggccactca tttgcaaggc caatacagcg tgggacagga gattagtttt
    40201 aaagaaaaag aagagggtca ttcctcttta aaagaccata cttataccat tactggtttt
    40261 gtggattcgg ctgaaatcct ctcccagcga gatatgggct acgcaggaag tggaagtggg
    40321 actctgacag cctatggggt gattttacct agtcagtttg atcagaaagt ctacaatata
    40381 gctcgtttga aatatcaaga tttagcaggt ttaaatgtct tttcatcagc ttatgaagaa
    40441 aaatccaagc aacatcagga agagcttgaa caaattttat cagataatgg caaggtacgt
    40501 ctgcaacttt tgaaaaaaga aggacaagag tctctagaca aggggcaaga gacccttgac
    40561 aaggctcaga ctaatttgca ggaaggcaag cgtcgtttag cagctgctca agctcgtata
    40621 caggctcaag aaagtcaact agccttgttt cctcaagttc agagagagca ggctagtgct
    40681 caacttaccc aagccaagca ggaattgggc aaggaagagg acaaactaaa gcaagctgaa
    40741 caaaatctag cccaagaaaa ggaaaaatta gaaaaacatc agcaagtctt ggacgatttg
    40801 gcggagccaa ggtatcaggt ctataatcgt cagaccatgc caggtggtca gggctatctt
    40861 atgtatagca atgcttcatc cagtattcga gcagtgggca atatctttcc tgtggtactt
    40921 tatgccgtag cagccatggt gacctttacg accatgactc gctttgtaga cgaagagcga
    40981 actcatgcag ggatttttaa ggccttgggt tatcgtagta aggatattat cgccaagttt
    41041 ctcctttatg gactagtagc tgggactgtc ggaacggctc taggtagtat acttggtcat
    41101 tatttgctag ccagtgtaat ttcaagtgtc attacaaaag gcatggtggt gggagaaacc
    41161 cagattcagt tctattggac ctatagctta ctagcttttg tcttgagctt gttggcgagt
    41221 gtgttaccag cctatctggt ggcttggagg gaacttcatg acgaagcagc ccagcttcta
    41281 cttcctaaac ctcctgtcaa aggagctaaa atcttattgg agcgtatcgg ttttatctgg
    41341 cgtcgtctca gttttactca taaggtaaca gcccgcaaca tctttcgtta taagcagaga
    41401 atgttgatga caatctttgg tgtggcaggt tctgtagctc tgctctttgc aggtttggga
    41461 atccaatctt ctgtagcagg agttccgtct aaacagtttc aacaaatcca acagtatcag
    41521 atgcttgtct ctgaaaatcc tagtgcgacc aatcaggaca aggtagagct agcagaagtg
    41581 ttgaaagggc aggagatact agcctaccag aaaatctatt ctaaagcgct atacaaggat
    41641 ttcaaaggca aagctggtct tcaaaacatt actcttatga tgatagagaa ggaagatttg
    41701 actcccttta tccatcttca acatcatcag caggagctga cattaaaaga tggcatcgtt
    41761 attacagcta aactcgccca gctggcaggt gtcaaggttg ggcagacttt agaaattgaa
    41821 ggtaaggaac taaaggtcgc tgctattact gagaactacg ttggtcactt tatttatatg
    41881 agtcaggcta gctatgagca actttacgga cagctacccc aagccaacac ttatctggtc
    41941 tcattaaggg ataccagtgc aactagtatc gaaagtcagg cgggcttgct tatgaatcaa
    42001 tctgcggtgt ccagcgttgt ccaaaatgct tcagccattc gactcttcga ctctatcgct
    42061 agctcactca atcagaccat gaccatcttg gtcatcgtat cggttctatt agctattgtc
    42121 atcctttaca atctgaccaa tatcaacgta gctgagagaa tccgtgaact ctccactatc
    42181 aaggttcttg gttttcataa taatgaagtc accctctaca tttaccgtga gacgattgtg
    42241 ctgtcccttg tgggaatcgt acttggtctg atagctggtt tctatttaca ccaatttttg
    42301 attcaaatga tttcgcctgc gactattctc ttttatccgc aggtaggctg ggaagtctat
    42361 gtaatcccag tggcagcagt aagcatcatt ttgaccttgc ttggtttctt cgtcaattat
    42421 tatctgagaa aggttgatat gttagaagcc ctgaaatctg tagagtaagg tagttatttt
    42481 tagctgattg aacttctatt tactaatatt caaaaatcct ccgtttcaaa gagcagggaa
    42541 ctctttgtga cagaggattt tttctatagg gctttagcag ctgcaattgc ggcttcgaag
    42601 tttggctcag aattgatatt atccacgtat tcaacgtagc gaatcgtatt gtcagtatcg
    42661 aggacaaaga ctgcgcgtgc taataggtgc cattcgttga tcaagagggc ataatcgtgc
    42721 ccgaaagaat ggtcaaagta gtctgaaagc ataatggcat tgtcaaggcc ttcagcaccg
    42781 caccaacgtt tttgagcaaa aggtaggtcc attgaaacag tcaatacgac cgtgttgtcc
    42841 agtccagcca attcttcatt aaaacgacgt gtttgagttg agcagatgcc tgtatcgata
    42901 gaaggaacga cactcaagac ttttttcttg ccatcaaaat cagccagaga ttttttagaa
    42961 agatctgttg tagtaagaga aaaatcaagc gccttgtcgc cgacttgtag ttgtttacct
    43021 gtaaagctca caggatttcc gagaaaagtt accataggat actccaatct tttttcttcc
    43081 attgtatctg aaacagtcag aattttccaa tgatttgacc ggaaatgtgg gcatagaaaa
    43141 aacgccagct catatgagaa tgacgttttt cagaggctta ttttgccaat ccttcagcaa
    43201 tcttgtcaag gttgtatttc atcatgctgt agtagctgtc gccttcttta ccttgttctg
    43261 cgatagagtc agtaaagatt tgtgcgtaga ttgggatgtt tgtgtcttga gaaacggttt
    43321 tcattggacg gtcatccaca cttgattcta caaagagtga tggaactttt gtttggcgaa
    43381 gtttttcaac caaggtcttg atttgttcag gagttccttc ttcttcagta ttgatttccc
    43441 agatgtaggc acttggaaca ccataggctt tagagaagta tttgaatgct ccttcgctgg
    43501 ttacaatgag tttcttttca gcagggatct tattaaattt atccttactt tctttatcaa
    43561 gtttgtctaa cttatcagta tattctttga gatttttttc atagaattct ttattgttag
    43621 ggtctttggc gctcaattgt ttggcgatat ttttagcaaa aataataccg ttttcaaggt
    43681 taagccaagc gtgtgggtct tcttttcctt tttcattttg accttcaagg tagataacat
    43741 caacgccgtc gctgactgcg aagtagtctt tgttttcagt tttcttggca ttttctacca
    43801 attttgtaaa ccaagcattg ccacctgttt caaggttgat accgttatag aaaatcaaat
    43861 cagcctcaga agttttctta acgtcttcag gaagtggttc gtattcgtgt gggtcttgcc
    43921 caatcggaac gatactatga aggtcaattt tgtcaccagc aatattttta gtaatatcag
    43981 cgatgattga gtttgtagca acaactttta gtttttgacc agaagttgtt gctttttttc
    44041 cgctagcaca tgctacaaga atgattgcag aaagaaagag aacgagtaat gtacctaatt
    44101 ttttcattag atcctccaat ttattagggc tttgcccctt attttaacaa atgtttattt
    44161 ttcagtttca aatatcgttg tttgggagcg ataaagaagc taatgagaaa gaaactagca
    44221 gctgtaagca cgatactaga acctgccgca acattaaaac tatagccaat aaagagtccc
    44281 aaaactgaag cagtagctcc gaaggttgag gaaaggaaaa tcatgctttt cagactatta
    44341 gcatacagat aagcagttgc agctggggta atcagcatgg ctacaatcag gatagttccg
    44401 acactttgca tggctgtcac agacacgaga gtcaggagta ccatgagaag gtagtgatag
    44461 aaattgacag gcattcccat ggctttagcc aagagttcat caaaggaagt tatcaagagt
    44521 tgcttgaaga aaatccagat taacaagagg atggctgccc ccacacccat agtaataaac
    44581 atatccgtat cttggacggc caggatatta ccaaaaagga tatggaaaag gtcagttgaa
    44641 cttttagcga caccaatcaa gatgataccg agggctaaga aagaagaaaa ggtaatgccg
    44701 atggcggtat cgcttttgat aatcgagttt cctttgatgt aggtaatgat gatggcagct
    44761 agcaatccaa agacaatggc tccgataaag aagtcaaggc ccaagatgaa ggagagggct
    44821 acacctggta agacagcatg tgaaatggca tctcccatga gtgacatccc gcgtagaata
    44881 atgaaacatc ccacggctcc agctacaatc ccgacgacaa tagctgttat caaggcattt
    44941 tgtaggaaat ggaatttttg caatccatcg ataaattctg caatcatagg tcacctccat
    45001 tgaaaaagag ttgattaccg taagcttctt ttagattggt ttcggtaaaa gtttcttttg
    45061 ttggaccaaa ggcaatcact tctcgattga caagtaagac ttgatcgaag tagtggggaa
    45121 tcttgctgag gtcgtggtga acgatgagaa ccgtcttccc agcttttttc aaatctctca
    45181 gcgtattcat gatgatttcc tcactgacag agtcaatccc agcaaagggt tcatccaaga
    45241 ggatatagtc ggcttcctgc accaaacatc tggcaatcaa gacccgctgg aattgacctc
    45301 cagacagttg actaatttga cgttcagcgt agtcagctag gccgacgatt tcaagggcct
    45361 cttgcacttt cttccaatgt ttagccttta aacttcgaaa gagaggaata gagggaaata
    45421 gtcctaacga gacgcattcc ttgaccttga tgggaaagtt gtagtcgata ttgatttttt
    45481 gttcgacata ggcaattcgg tgtaaggatt ttttaacttc cttgtcatcg agaaatgcct
    45541 gaccttgatg tgggataatt cccagcatac cttttaatag tgttgatttc ccagcgccgt
    45601 ttggaccaat gatgccggta attgttggtc catggagcac tagtgaaata tccttaagtg
    45661 ccaacgtttc tttgtaggag acactgaggt tttcgatacg tatcataaac ttgtattcct
    45721 cctgtctctt aatatacatt aaaaaaaaaa ttaagtcaag ttaatttttg aaaaaattaa
    45781 aataataact gaaaaataga ttctaaagat aactttcagg ataaatttct aaattataaa
    45841 acgcatagta tcaagtgtaa aaaacttgga attatgcgtt ttatcatgga aagatttttt
    45901 ataatagcta aaaaataata gttaaatggt tattaattgc attccctagt gatttttgtt
    45961 aagataaatg caaatacaaa tgaaagcgag aacaagatga cacgttatca agatgatttt
    46021 tatgatgcta tcaatggaga atggcaacag acagctgaaa tcccagcaga taagtctcaa
    46081 actggaggtt ttgttgattt agaccaggaa attgaagacc tgatgctggc gacaacagac
    46141 aagtggttag caggtgaaga agtgcctgag gatgctatct tggaaaactt tgtcaaatac
    46201 caccgcctag ttcgtgattt tgacaagaga gaagctgacg gtatcacacc tgtcttacca
    46261 ctccttaaag aattccaaga attggaaact tttgcggatt ttacagctaa actagcagag
    46321 tttgagcttg caggaaaacc aaacttcctt ccttttggtg tatcgccaga ctttatggat
    46381 gctagaatca atgttctatg ggctagcgct ccaagcacaa tcttgccaga tacgacctac
    46441 tatgcagaag aacatcctca gcgcgaagag ctcttgactc tttggaaaga aagcagcgca
    46501 aatctcctca aggcttatga tttctctgat gaagaaattg aagacttgct agaaaaaaga
    46561 cttgaattgg accgccgagt tgcgacagtg gtgctctcta atgaagaaag ttcagaatat
    46621 gctaaactct atcatccata ttcttacgaa gatttcaaga aattcgcgcc tgccctacct
    46681 ttggatgact tcttcaaagc agttattggg caattaccag acaaggttat tgtagacgag
    46741 gaacgtttct ggcaagcagc agagcaattc tacagtgagg aagcctggtc tctccttaaa
    46801 gcaaccttga ttttgagtgt tgtcaatctt tcaaccagct atttaacaga ggatatccgt
    46861 gttttgtctg gtgcctacag ccgtgccctt tctggagttc cagaggcaaa agataaggtc
    46921 aaagcagctt atcatctagc acaggaacct ttcaagcaag ccctggggct ttggtacgcc
    46981 cgtgagaagt tctctccaga agccaaggcg gatgtggaga aaaaagtggc aaccatgatt
    47041 gatgtctata aggagcgtct gcttaagaat gactggctca ctccagaaac ctgtaaacag
    47101 gctatcgtga agctcaatgt gatcaaacct tatattggct atccagaaga attgcctgca
    47161 cgttacaagg ataaggtagt gaatgaaact gccagtcttt ttgagaatgc tctagccttt
    47221 gcgcgtgtgg aaatcaagca cagttggagt aagtggaacc agcctgtaga ctataaggaa
    47281 tggggcatgc ctgctcatat ggtcaatgcc tactacaatc ctcagaagaa cctgattgtc
    47341 tttccagcgg ccattttaca ggcgcctttc tatgacttgc atcagtcatc ttctgctaac
    47401 tacggtggta ttggggcagt gattgcccat gaaatttccc acgcctttga tactaacggg
    47461 gcttcctttg acgaaaatgg tagcctcaag gattggtgga cagagagcga ctatgctgcc
    47521 ttcaaggaga aaacacaaaa agtcattgac caatttgatg gacaggattc ttatggagca
    47581 accattaacg gtaaattgac tgtatcagaa aacgtggctg acttgggagg aatcgcagca
    47641 gcgcttgaag cagctaagag agaagcagac ttctcagcag aagagttctt ctacaacttc
    47701 ggtcgcatct ggcgcatgaa aggtcgtcca gaatttatga aacttttggc tagcgtcgat
    47761 gtgcacgcac cagccaaact ccgtgtcaat gtgcaagtac caaacttcga cgatttcttt
    47821 acaacctatg atgtcaaaga aggagacgga atgtggcgtt caccagagga gcgcgtgatt
    47881 atttggtaat acaaaaaatc tagtcatcag aaaaaaggca tccaatcacg tgtgaaaacc
    47941 ttgataggat gccttttgta atagaaagat ttgctggata gtttacttaa atttcgattg
    48001 tcatcatctt gctagaaaaa gggattgaag gccttttcgt gagcgatagt agtagctgga
    48061 ccatgtcctg gatagacatc gtagtttggt agggtgaaga gttgggtctg gatactatga
    48121 aggagttgct ccatgctacc agtcggaagg tcggtccgtc cgatagtttc gcggaataga
    48181 gcatctcccg tcaagactag gtgagcatca ggaaagacta gggaaacacc accgatagag
    48241 tgccctgggg tcggtagaac cttaaaacga aattcctcta gttggtattc ttcgtgaaag
    48301 acaaaggtgt gttctgcagg ttttgtgacc acatctgcca tatcatcgtg gcgagggaga
    48361 ccggagagat tatcgacagg agtgtagagc cagctggctt cgctctctgc gatatagaca
    48421 ggaggattgc caaacgtctc gcgaaccaag tccagactca tgatatggtc ataatgggcg
    48481 tgggtcaaga gaatagcaca gatcggtttg ttgatcttct cgattgtctg acgaatggct
    48541 tcccaatgac taccaggatc gacgacgatg aggtgctttt cgccttctag ataataggta
    48601 ttttcatagg caacaggatt cacggtttta tggattttca tactagctcc aatctcaaag
    48661 aatgtactaa tactcttcga aaatctcttc aaaccgcgtc aactttatct gcaacctcaa
    48721 agcagtgctt tgaacagcct gcggctagct ttctagtttg ctctttgatt ttcattgagt
    48781 ataaattaag tatagcacag ttagggagaa taggtaagga tttaaaatga acttaaaaac
    48841 cagcatgact agatgaagac aggctggtta tcaatttatc aatattggaa aggtgtcaat
    48901 tgcccttcat aggttgcata aactccgtca ttagcttgtt tgatagacgt gatgtttaga
    48961 gtgctaccgt agttggcttc tcatttgtcg ctatattcac tataagttat cctactgggc
    49021 aggttctggt cgttagcata gtattgaacg actgtttttt atagttttgc tggctgaata
    49081 ggaacaggca gcaaactcct aacattagga gagcaaagat agaaatagca gtttttttca
    49141 taggtattct ccttataaac taaaggatag aagaaagtat cttgaggatt tttatactct
    49201 tcaaaaatct cttcaaaccg cgtcaacgtc gccttgccgt atatatgtga ctgactttgt
    49261 cagtcttatc tacaacctca aagcagtgct ttgaacagcc tgcggctagt ttcctagttt
    49321 gctcttggat tttcattgag tattaattcc aaaatccagt caaggtacca gtgtatgtga
    49381 tacgagttcc accgtttatc tttcgtatct tcaatggaat tggggaaatc agaaagtctt
    49441 tgggttacaa tatggtttcc gttcttctat ctctccttct atcacctaag tttaaaatct
    49501 aacttcgtag tatattatgg gccaataatt cagaattatc aagcaatttt gaattatttt
    49561 tttcttattc tgttccaatc tagttttcat attcttaaaa aagtgataaa atggtaggaa
    49621 gaattggaga gtagagatgc cgaaagaagt gaatttaaca ggcgaagaag ttgtcgcttt
    49681 aaccaaagaa tatttaacgg aagaggatgt tcattttgtc cataaggcct tggtctatgc
    49741 tgttgaatgc cacagtggtc aatatcgcaa atcaggcgag ccttatatca ttcaccctat
    49801 ccaagtggca ggtattttag ctaagctaaa gctggatgct gtaacagtag cttgtggatt
    49861 cttgcatgat gtggtggaag atacagatgc gaccttggac gatttggaaa gagagtttgg
    49921 tcctgatgtg cgggtgattg ttgacggagt taccaagctt ggcaaggtcg agtacaaatc
    49981 gatcgaggag caattagcgg aaaatcatcg caagatgctc atggccatgt ctgaggacat
    50041 ccgcgttatt ttggtcaaac tgtctgaccg cttgcacaat atgcggaccc tgaaacatct
    50101 tcgaaaagac aagcaggagc gtatttccaa agaaaccatg gaaatctatg ccccacttgc
    50161 ccatcgtttg gggatttcca gtgtcaaatg ggaattagaa gacttgtctt tccgttatct
    50221 caatccaacg gagttttaca agattaccca tatgatgaag gaaaagcgca gggagcgtga
    50281 ggccttggtg gatgaggtag tcacaaaatt agaggagtat acgacagaac gtcacttgaa
    50341 agggaagatt tatggtcgtc ccaagcatat ttactcaatt ttccgcaaaa tgcaggacaa
    50401 gagaaaacgg tttgaggaaa tctatgatct gattgctatt cgttgtattt tagataccca
    50461 aagtgatgtt tatgccatgc ttggttacgt gcatgaattt tggaaaccga tgccaggtcg
    50521 cttcaaagac tatattgcca accgcaaggc caatggttat cagtctatcc atacgactgt
    50581 ttatggacca aaagggccga ttgaattcca gattcgaacc aaggaaatgc acgaggtggc
    50641 tgagtacggg gttgcggctc actgggctta taagaaaggt ataaaggggc aagttaacag
    50701 caaggaatca gctattggaa tgaactggat caaggagatg atggagctcc aagaccaggc
    50761 tgatgatgct aaggaatttg tggactctgt taaggaaaac tatttggctg aggagattta
    50821 cgtttttacc ccagatggag ctgtccgttc ccttcccaaa gattcaggac cgattgattt
    50881 tgcctacgaa atccatacca aggtcggtga aaaagcaact ggtgccaagg tcaatggccg
    50941 catggttcca ctgacaacca agttaaagac aggggatcag gttgaaatta tcgccaaccc
    51001 gaactccttt ggacctagcc gtgactggct caatatggtc aagactagca aggcgcgcaa
    51061 taagattcgc cagttcttta aaaaccaaga taaggaattg tctgtcaaca agggtcgtga
    51121 gatgctgatg gctcagttcc aagaaaatgg ctatgtggca aataaattta tggacaagcg
    51181 ccacatggat caagttctgc aaaagaccag ttacaagaca gaagactccc tctttgcggc
    51241 cattggtttt ggggaaatcg gtgcgattac cgtctttaac cgtctgactg aaaaggagcg
    51301 ccgtgaggaa gagcgtgcca aggccaaggc tgaggcagag gagcttgtca aaggtggcga
    51361 ggtcaaggtt gaaaataaag aaactctcaa ggtcaagcat gaggggggag tggttattga
    51421 aggtgcttct ggtctcctag tgcggattgc taagtgttgt aaccccgtgc ctggtgacga
    51481 tattgttggc tacattacca agggtcgtgg tgtggctatt caccgtgtgg actgtatgaa
    51541 cctgcgtgcc caagaaaact acgagcaacg tctccttgat gtggaatggg aagaccagta
    51601 ctctagctca aataaggagt atatggccca tatcgatatc tacggtctca accgtacagg
    51661 actgttgaac gatgtactgc aagttctttc aaatacaacc aagaatattt caacggtcaa
    51721 tgcccaacca accaaggata tgaagtttgc taatatccat gtgtccttcg gtattgccaa
    51781 cctctctaca ctgactacgg ttgtcgataa aattaagagt gtgccagaag tttactctgt
    51841 caaacggacc aacggctagt tgtcctagct cttactagaa aggctattat gaaaatcatt
    51901 atccaacggg ttaaaaaagc ccaagtgagt atagaaggcc agattcaggg aaaaatcaat
    51961 cagggacttt tattgctggt tggtgttgga ccagaggacc aagaggaaga tttggactat
    52021 gctgtgagaa aactggtcaa tatgcgaatt ttttcagacg cagaaggcaa gatgaaccta
    52081 tctgtcaaag atattgaagg agaaatcctc tctatttctc agtttaccct ctttgcggat
    52141 actaagaaag gcaatcgtcc agcctttaca ggggtagcta aacctgatat ggcatcagac
    52201 ttctatgatg ctttcaatca aaaattagcg caagaagtgc ccgttcagac aggtatcttt
    52261 ggagcaaata tgcaggttga gctggttaat aacggacctg ttaccattat cctagatact
    52321 aaaaagagat aagaaagacc aagcccagtc ggcttggtct ttctcatcta tcataaaata
    52381 ctccaaaaag aaatcggttc ttgatatgct tgggggaagt ctcttttcag gctttggcag
    52441 atgcgatagg aagggatgag atgtcctagg atgaggagag ttccctgaag gaaaagtgga
    52501 atatcactta aagacaccaa ggagagaatc atcaggctat cccataggag aatttgtaaa
    52561 gcaaaacgcc agaatctcgg tctaatctgg gaatagagtt gactaaagtg gtcacaaagt
    52621 tggtttgaaa gataggtcaa tagcacagga tgaaagaaaa tgagccaacc gctataaatc
    52681 aaaatccagt cccaagtaag cccccctttt taaatgtcaa aaatgccagc atgattccat
    52741 caatgacaag gagttgaatg gttttgatga agatgatttt tttcatgcta aaacctcctt
    52801 ttccttagag acactcccct acaggtattt tagaatgtat attgcttaga tattccttat
    52861 tttattagct ttttaaggta ttaaagtagt tatataagtt tatgaagggt atcctatcct
    52921 gcacggctaa ttttgagttc gaaactgagg agtttataac tcaaaatttc gattaaatca
    52981 gcatttaacg atagtatgtt tgtcataaaa tgataaattt ttagattgtg gaaatttttt
    53041 ttaacttaat tcttgatttt ttttctaaat gtgatatact taatttacgg gataaaaaaa
    53101 ccaccttaga aaggtgtgat aatgtgcaaa aagagaatgt tagaatgcgt ttagcgtctg
    53161 aatccagaca gatattagat aagcttaaag atgatgttta caataaatta ggctatgaag
    53221 taagctattc cagtattgtt agtcaagctg ttagagaata cgttcctaaa aaagaacgta
    53281 tagattggat aaaattaaaa gagacagcta tacccttttc atcgttaaaa cagagcaata
    53341 attgggagta ccagacatca cttatgttag aggaagatgt attaatctta ctgtctgaac
    53401 tacaaaattt tttcttagat gtcttccaag cgaaacgtat acatagggca ttttgtgtac
    53461 gcctatgctt gaaagcacaa tttttattaa gtaataatga ttcttaatac tatcaatatt
    53521 aatgcggagt gtaatgctcc gctaaaataa aacctattac gggataaaaa cactacttta
    53581 tttaggatgg aaagaggaac gaatgaagat gaaagctaga gattcaccat tgaattgatt
    53641 ttgtttttag aaaaaatcaa taattagaaa aaatacgagg taaaaaaatg aatagagatg
    53701 tattagagtt tctgagaaca gagaccgctg aaaaaattag tctttatata agcgaggcta
    53761 atagattgga gggcgatgta actctactcg cacctagttc tcaagatttg gaagatatta
    53821 aaaatgctat gctttccaat tctaatctcg gattaaaagt tgcgagactg gatgtgatga
    53881 agaaaatagc atatgcttct acaagaaatc attatttaac aggggctacg atttttgggg
    53941 atatttcgaa aggaacatac aattgtgatc ctaaaagtta tgtctaatat aagggaggtt
    54001 aatccctccc cttgtttttg aaaatcgaaa ggaaaagtat aaaaatgaaa gttaatgaat
    54061 atttctggag aacgagctgt cttatactaa aaaagaagaa atcgataaaa tagtatacgt
    54121 gttagagatg tgtttgtcgt aaaagtctgg atagttttct cctaggtagt cagctgtcat
    54181 ataataaaaa gtagaatggc aagcagtgat aattggcata agagatgaaa aacgctgaga
    54241 actaatgaag gctaagagaa caaaaaatag aaaatcaatg gtgagaaccc ctaaatagta
    54301 gaagcgaatc tttttattga tttgaggata aatctcagcg aattgatgtt tgagtcggac
    54361 gaccaagaga aatagcagga gtccttgagc aaggaagaaa attaaaccag agagcaagag
    54421 ccactcaaaa gatgtctcga gtctagtgat aaaaaatgca aatagtagca aatcaataac
    54481 tgcaattgct ataaaatgga ttctatagag ttttttcatg acaagacctt cctcttttat
    54541 ctaacttcat tctactccaa aagaatggga gttacaacta aaatgataaa aatagcagaa
    54601 gggagattct cttaagttgg ctagtattct ttatttgagt ttccttctat gtatctaact
    54661 tcttcatcat tccagacaaa taaagctccg attgcattga ggatataaaa gatgtattta
    54721 ccgatattgg cgaagtttcc ttgaatacca gcttttgtca gctgaacgaa attgtaaatc
    54781 aaccaaaagc cccactgagt tgttagtttc aatgcattca aagcattggc aatgagggac
    54841 agtgcaaagg caatagttgt tacgtaggca aggagattca tcttgccctc atatccgata
    54901 tagttggtca caaaggcaaa gaggaaggcg atgatggaaa tgatgatggc cgccaatttt
    54961 acctgttttt ggctcatttg gttgggtctg ccttcttgcg aagctttcca tttctttata
    55021 gcaaaggtat aaatgaggaa ggtgacggga taggtaatga tggccgcctt atttccaagg
    55081 atataatcaa tagcaccgga caaaatggta ttaacaatac caaagtaatt tccccatttg
    55141 cttaatttcc ccgtgaaacg agtggacaac atggaaatcc caacgttggt tacggaaatc
    55201 aatccaaagg gtacaagagc tgtccatggt ccccagtcta caaatttatc gaggcgtgag
    55261 ttgaggtaac cagatgcaat cgcaatccaa cgaccaaagc aaccccgaag aggtcaaact
    55321 atttagatgt agcaaaaatt tttagtgatt ttttcatagg ttaaactacc tttctttttt
    55381 tcaaatattc tcccaccaaa tgaaagtaaa ataaaatgat agaaataaaa ccctgaaaat
    55441 aaaactttca gggttggtag gggacttgag aaattagttg attttctcga catagagttg
    55501 ttttgcaatg tccatattca cttgtaaatc ctcgtcgtta ctgaggatag tgaaggtatt
    55561 gctgaagcca tcaaactgct tgacttggag ctggtcaccg atgtgaagtg agtgcttgtc
    55621 cagataatgg agaatgtcaa aactatcgtg cacccgagtc aggcggtagg cgccagcttc
    55681 cttgatatca gctagtggga ggttattgat ttcaacgagg agttctccct tggcaggaat
    55741 agttcctccg tgggggcagg ttttagggaa acctagcagt ttatctagtc tttccacgaa
    55801 caggtcagag acagtgtgtt ccaagacctc agcttcctcg tgaatctggt cacttgtata
    55861 gtctaaatga tgaactagaa aaacttcaat caagcggtgc ttacgataga gctcagagac
    55921 cagtttgaga ccgaggtcag tcagtagata gccacattcc ttgtccttta ggatgagatt
    55981 ttcacttttc attcgtttga tcatttcagt tacggcaggg ggagagactt gcatgcgagc
    56041 cgcaatttcc ttgttggtaa tcttatgcag gtctatgcca atttcataaa tacattttag
    56101 atagtcttct ttgtttgggg tcattcgttt cctcttgtct aatatcttta tctagtatat
    56161 caaaaaaagc tagatttctc tagctgtgac tttttatgtt atacttattg caagagaaaa
    56221 aacgaggaga tggatatgac gaaaatagct cttctttcag atattcatgg aaataccacc
    56281 gccttggagg ctgttttggc agatgctcag cagctaggag tggatgaata ctggcttttg
    56341 ggagatattc tcatgccagg gacaggacgt agaaggattt tggacttgtt ggatcaacta
    56401 ccgattacgg ctagagtttt gggaaactgg gaagacagtc tttggcatgg tgtccgtaag
    56461 gaattggata gtactcgccc tagtcaacgc tatctcttgc gccagtgcca gtatgtttta
    56521 gaggaaattt ccctagaaga aattgaagtg ctccacaatc aacctcttca aattcatcgt
    56581 cagtttgggg atttgacagt gggaattagc catcatctgc ctgataagaa ctgggggcga
    56641 gagttgattc atactggcaa acaagagaat tttgaccgct tggtgactca tcctccctgt
    56701 gatattgctg tttatggaca tattcaccag cagttgcttc gtcacgggac tggtgggcaa
    56761 ttgattgtca atccgggttc gattggccaa cctttctttt tggacgctca gctacggaag
    56821 gacttgcggg cccagtatat gattttggag tttgatggca agggcctggt agatatggac
    56881 ttccgacggg tagactacga tgtggcagct gaattgcagc tggctaaaga cctgagactt
    56941 ccctattttg aggtttacta tgaaagtctg gtcaatggga tccaccatac tcatcatcag
    57001 gaatttttga gagaattggc tcagaaagag ggttgcgatc gggagttaga cgactggttg
    57061 aaaagtggta acgattgaca ttacaactaa aaagggtata ataatagaaa aagaagagta
    57121 gaggcagggt agcctcgtaa aaaggagaag aggatgcaaa ttccaagtag atttaccatt
    57181 gcgactcata tgctgataat cattgccctc gaggggaagg aaagcaaggt gaccagtgat
    57241 tttctggctg ctagtgtcgg ggtcaatcct gtcattatca gaaagatctt gtcccagttg
    57301 aagaaggcag agctgatttc agtagcgcgt ggaacgggcg gaacagagat tgtcaaggac
    57361 cttaaggata ttagtctttt agatgtttat caggcggtcg aatgtcttgg taagacaggt
    57421 caactcttca gtttccatga caatccgaat ccaaattgcc ctgtaggagc tcatattcat
    57481 gatgttttgg atcaaaaatt ggagagaatt cagttgacta tggaggcaga acttggtcag
    57541 accagtctag aaaaagtcgt ggccgatgca gagagtcaga tgaaggatta agagggataa
    57601 atgccctctt tttttctttg gataattatg ataaaatgta gctattaaag gagtaagaaa
    57661 tgtatctcgt tatagaaatt gtattagcct ttatagtgtc attttggaag gataatagaa
    57721 gtttgtggaa tccagtatta tttttattat ccctcatttc aagttatttt tatctatcct
    57781 acctttttta taaaaatgga tacgagaatg ttcagttagc tttttatgta tttacctttg
    57841 tcttacttcc ttttttgctt tttctaagtg gcatcttttt aatctataat ggggtcattt
    57901 tgttgaaacg agagggacgt tccaagcccc attatctctc aatgctcttt gatttttatt
    57961 gactattaga ttctatttaa aaagacttag aatgcacatg aaagtatgta ttctaggtct
    58021 tttgttttgt atacatttaa ttttcaagag tattatctat ttttccatgc atggtaacga
    58081 gtatcaatca ataactgggt aaggcgaccc aaggtttctc tttcttctgg agtgagggat
    58141 tgagcttgga caaagagatg atgaatgtat tcaagcgcct ttaaggaagc caagtcattg
    58201 atagagctaa taccagcatc aagaatagtg ccaaagaaga ggtcgaagta gagctgaagt
    58261 tcttcgtcag ggactgtggc cacccattct ttaaaggttg tgtctacttg ccggctatca
    58321 ctgttggtct tatccagttg aacgaagtgc ttgtcctcaa tctgccaact aaaggtatcg
    58381 tgctgggcga tgccacccag ggcagtactc tgaacgatga tttggtgagc aggaatttcc
    58441 agcatcatac cgataataga cccttgtgga atgaatatct tgcttctatc cattatcctt
    58501 tgataacccg cagtctgtgt caattcttga tggagaccag gtgcatcaaa tgtataaact
    58561 gctgtgatct gattttgcaa actttgctca atttggctag cagcatagat agcgagattt
    58621 cctcccttgg aatgcccagc cagaataacc ttttgcttag gatgatgggc aaaaaagttc
    58681 tttaaatagc gaagggcgtg cttttgagca ggaatttcct tcatataggt caggtggaaa
    58741 tcttccttcc agccaatgat actgtcatct gtcccacgaa agacaatcag ataggtatcg
    58801 aggctgacac gataagtcat agccgcaaat tgcttttgca gttcagggtc gatgtcgttg
    58861 ataaaatggg agagtttgca atttttgaag cgcttgtgtt gagccaattc atctaataat
    58921 tgaaggcgat ttttgctagt aagcatggtg ggctctcttg gaacctgagg tgctagatct
    58981 aaaagacgtt gaggaagtgt ggagaccaga ttatcaaagg agaggtaggt gatttctatt
    59041 aaggttagaa tgtctaactc attcaaggga aggtcgtaat aagaatcata tgcgacatct
    59101 ttcagatagt caaaaatatt ggccataaga gctcctttct ttttatttat cttagcaaat
    59161 ttccctcaaa ttagctagta gcatagcctg tttgtactgg ctaaaaacag gctatttcaa
    59221 attcagtttc agaccatcta gcatggaaaa atctgttata ataatggaaa aggagaagcg
    59281 catgcacaag attttattaa tagaagatga tcaggtcatt cgtcaacaga ttgggaaaat
    59341 gctctctgaa tggggatttg aagtggtcct ggtagaagac tttatggaag ttttgagtct
    59401 atttgttcag tcggaacctc atctggtcct catggatatt ggtttgccct tgtttaatgg
    59461 ttatcactgg tgtcaggaaa tccgcaagat ttccaaggta cctatcatgt ttctttcttc
    59521 gagagaccag gctatggata ttgtcatggc aatcaatatg ggggcggatg actttgtgac
    59581 caagcctttt gaccagcagg ttcttttagc taaggttcag ggcttgttgc gtcgttccta
    59641 tgagtttggg cgtgatgaga gtttgctgga atatgctggt gttatcctca ataccaaatc
    59701 catggattta cattatcaag ggcaagtctt gaatttgacc aagaatgaat tccagatttt
    59761 acgcgtgtta tttgagcatg caggcaacat cgtagcacgt gacgacctga tgcgggaact
    59821 ttggaacagt gactttttca ttgatgataa taccctctct gtcaatgtgg ctcgtttgcg
    59881 taaaaagttg gaggagcagg gattggtagg atttatcgag accaagaaag gaatagggta
    59941 cggattgaag catgcttgat tggaaacaat tttttctagc ctatctgcgc tcccgtagtc
    60001 gtctttttat ctatctgctt tttttggcat ttcttgtctt actctttcag tttttatttg
    60061 ccagtctagg aatttacttc ctctactttt tcttcttgtg ttgctttgta accatcttat
    60121 ttttcacttg ggacatattg gtggaaacgc aggtctatcg ccaggaactt ctctatggag
    60181 agagggaagc caagtctcct ttggaaatag ctttagcaga aaaattagaa gcgcgtgaga
    60241 tggaactcta tcagcagagg tcaaaagcag aaagaaaact gacggatttg ctggattact
    60301 ataccttgtg ggttcatcag ataaagaccc ccattgcagc cagtcaactc ttagttgcag
    60361 aagtggtcga ccgccaactg aagcagcagc tagaacagga aattttcaaa atcgactcct
    60421 ataccaacct agttttacag tacctgcgtt tagaaagttt ccatgatgat ttggtcttaa
    60481 agcaggttca aattgaggac ttggtcaagg aaataattcg taaatatgct cttttcttta
    60541 ttcaaaaagg cttaaatgtc aatctacatg accttgataa agaaatcgtg acggataaaa
    60601 agtggctgct agtggttatt gagcaaatca tctcaaacag tctcaagtac accaaggaag
    60661 gtggtctgga gatttatatg gatgaccaag agctttgtat caaagatacg ggaatcggga
    60721 taaaaaacag tgatgtcctc cgagtatttg aacgtggctt ttcaggatac aatggccgtt
    60781 tgacccagca gtcctctgga cttggccttt atctatctaa gaaaatttct gaagaactgg
    60841 ggcaccagat tcgtatcgag tctgaggtcg gaaaaggaac gacagtgcgg attcagtttg
    60901 ctcaagtgaa cttagtcctt gagtaaaaat agatgagaaa aagcctccag attggaggct
    60961 tttatgctag actcttattt ctcaacgcgt gatttgttgg cgatatcagc taggatagct
    61021 tgaacaaaat tatcaactga gacagtttgt gtttcttttt ggccgtagcg acgaacgttg
    61081 actgtttcgt cttccatttc tttgtctcca acaattaatt ggtaaggaat cttgctggtt
    61141 tgtgaagcac ggatcttgaa ctgcattttt tcattgcgct catctacgtc tgcacggaca
    61201 ccgcggtcac ggagtttctt ggccacttcc caagcgtagt tcacgtgttt ttcgttagat
    61261 actgggatga gggttacttg gtgtggtgcc agccatgttg ggaaggcccc cttgtagttc
    61321 tcaatcaaga tagctgtgaa gcgttccata gttgagataa ccccacggtg gatcatgact
    61381 ggacggtgat cttcgccatc agctccgatg tatttgaggt cgaagcgttc tggcaacaag
    61441 aaatcaagtt ggatagtaga aagggtttct tcttttccaa gggcagtttt aatctggata
    61501 tccaattttg gtccgtagaa ggctgcttca ccttcggctt caaagtagtc cacgcccatt
    61561 tcatcaagag ctgcacgaag catggtttgg gcattttccc acatctcatc gttatcaaag
    61621 tacttatgag tatcttgagg gtcacgaaga gagaggcgga agcggtagtc agtcaagttg
    61681 aagtcttcat aaacatcgat aatcaactga agggcacgtt ggaattcttc ttggatttgt
    61741 tctggagtaa cgaataggtg accgtcgttg agtgacattt cacgtacacg ttgaaggcca
    61801 gtgagggcac cagatttttc gtaacggtgc atcataccga tttcagcgat acggattggc
    61861 aattcacggt aagagtgaac atggtgtttg aaaacttgga tgtggtgcgg acagttcatt
    61921 ggacgaagga caaattcttc cccgtcaccc atgtccatgg ttgggaacat gtcttcttgg
    61981 taatgatccc agtgaccaga agtcttgtaa agctcaacag aagcaagtgg tggagtgtag
    62041 acgtgttggt agccagaagc caactctttg tttacgatgt agcgttccaa ttcacgacgg
    62101 atagtcgcac catttggcaa ccagaatggc aaaccttgtc ccacttcttg tgaaatcata
    62161 aagaggtcaa gctctttacc aagtttacgg tggtcacgtt ccttagcttc ttcacgcatt
    62221 tgaaggtagt ttttcaagtc tttcttgtca aaccaagctg taccgtagat acgttgcatc
    62281 atagcgttgt cgctgtttcc acgccagtaa gcaccagcta catggagaag gtggaagatt
    62341 tggatacgac ctgttgatgg aacgtgaggt ccacggcaga ggtctacata ttcaccctga
    62401 cgatagatag tcaaaccgcc ttcgtcttct gagtgttctt caatcaattc caacttgtaa
    62461 gggtcatttt tgaagatttc acgtgcctcg tctttagtca cttcttcacg aatagatggg
    62521 aagttttctt tgacgatttt ttgcatttct tcttcgatac gaggaaggtc ttcgttagag
    62581 atttgaccag ctatgttgtc agtatcgtag tagaaaccat cttcgatggc tggaccaact
    62641 cccaagtgaa tgtctgggaa aagacgacga gctgcttggg cgaacaagtg agctgctgag
    62701 tgacgcaaga ttggaagggc atcttcgtga tcaggtgtca caatttcgat gcttccatct
    62761 tcagtgatag cgcgagtagt gtcgatgagt ttgccgttga atttaccagc caaggctttt
    62821 ttagctaggg aattgctgat agattgggca atttcaaaag ttgttacgcc agattcgaat
    62881 tcacgaacag cgccatctgg gaaagtaatg ttaatcatga tgttctcctt ttttattatt
    62941 tcatagtttc taagcattga ttttttatca gcagactact tccaagtcct aacgttcaat
    63001 tgcttttctt tatcagagag gaagttttcc atttccgtca gaatgtctat atccaaacgt
    63061 tgagaaagtt ctaatagcca ccagatattt tctgaaagtt tttgttccag tgtgtagggt
    63121 gtttcatcat agtagcgtcc ttgctttgtc atcaccaatc gttggaaatt tccaatatca
    63181 ttagataaag ccaagaggtc ttcttctacc gtccacttgg aatcatgatg cttaacttcc
    63241 agttcgtgat aagcttgtcg gattgcccaa ctgtgctcca ctaattcttg caactccata
    63301 attagtatcc taataaaaaa atgcgacatc ctcgaaagga cgtcgcaacg tggttccacc
    63361 ttcatttatg tacctcaaaa gagagggaca cctctgatcg gctctaacgt ggccaccgtt
    63421 ttatgttttc ataaaaaact caagagtagt atcagtttag acttcctatg cgtttccagc
    63481 aaccacgcac tctctagtag aaagggacta agtgacttgt ctctatggat tattatagca
    63541 tgattgtgag atttttcaag gattttgtga aagttttttg tttttcattt tttgtagaat
    63601 atgcttgatg ctaataccag aatccatgcc caccagagca actgtttcat agattagcaa
    63661 gtaaattagt ataaactcac caaagattat gatagtgaag taaaagagca gtccgttacc
    63721 aactaaccat caaagtgaga aacggaaacg gtagctatag agtaacgata caatcaagat
    63781 taccagaggt gtaaagaaga gaagattgtt tatatagagt cccttgagtg taagggggtc
    63841 agaaacaact agcaagaaca actcataaag tggccaataa atatgaccag atagtagggg
    63901 agatgggaat agaatctacg catgataatc acctcgtttt aaaaaaaaca gacaacttag
    63961 atctcttgct atgattatta taagcatgtt taaaacaaga aagtaaattt gttgacaaag
    64021 aagatttttc ttttcactag aatcatagtt agttttcttg gtagaaatat tttgataata
    64081 attaagcaag actattgaca ttgattatta agagtgtcac aattgctgta actaaaataa
    64141 ttacaacaag agaggtataa aaaatgaaac tagcagttat tgcagcaaat ggacaagtgg
    64201 ggaaagcaat tgttgaagaa gcagtcaaac gaggacatga agtaacggct attgttcgtt
    64261 ctgaaaacaa aagtcaagct gagtctatta ttaaaaaaga tttatttgag ttgacaaaag
    64321 atgatcttac tggatttgat gctgttattt cagcgtttgg tgcttataca ccagatacgc
    64381 taccgctcca tagcaaatca atcgaactat ttaatcagct tcttgctgga acacagacac
    64441 gttttctagt tgtaggggga gcagaaagtc tttatataga tgaaacaaaa acgacacgac
    64501 ttttagatac gtctgatttt cctgaagaat ttaagtcact agcaaaagct caagcggatg
    64561 aattggatct tcttcgtaca aaaaataatc tcaactggac ttttgtcagt cctgctgtag
    64621 attttattcc cgatggtgaa aaaacaggaa actacattct agcaggagaa atttttacta
    64681 ctaatgaaaa aaggaataag ccagattagt tatgcagatt atgctattgg attggtagat
    64741 gaacttgaaa aaggtcatca tataaaagaa cgtatctctt tacttgaaaa ataataacta
    64801 tgagagtatt aatgtttgac agaaaattta aatcttggta aaatagggat tgtcgtaaag
    64861 acaaataact tcttcttggt tacaggcatg ccaacctgtc actcggatga agccaaataa
    64921 aaaggagaaa catcatggca atctcaaaag agaaaaaaaa tgaaatcatt gcacaatatg
    64981 cacgtcacga aggtgataca ggttcagtag aggttcaagt tgctgtcctt acttgggaaa
    65041 tcaaccacct taacgaacac atcaaacaac acaaaaaaga ccacgctact taccgtggat
    65101 tgatgaaaaa aatcggtcgt cgtcgtaact tgcttgcata cttgcgtaaa aacgacgtta
    65161 accgttaccg tgagttgatc aactctctag gacttcgtcg ctaattcaag atacaaaggc
    65221 cgtcaaaagc acaaagcaaa aataggaaaa ttgacgaaga aacttcagtt tctaggagat
    65281 tttatctttt ttgccaagtg cttaggccgt gttcaattga gcatatcttg ataataaagc
    65341 tactctaaat tgggtagctt ttttgcgttg tcaccttacc tcgctatact caagtataat
    65401 ctttggttac ggttcctagc actgtaaggt aaaataaacc agcttttctc ccttcgggga
    65461 gatttttttt gtttcactga aagtttcgta cgatcttcgc ctcgtcgcct agtctataaa
    65521 cgatttatct agcaagaatc atgatgctaa gggcgtcaaa aatccgtatg aaaataggga
    65581 aatgacacag tgttcgatga gcacaaggag tttcatcttt ttcactagga ttttagcccg
    65641 ggctaaaatc agctctctga cttcagaggg cttttttatt gaggttttat cggtaacaat
    65701 tttggagact acaaaaacct caaatggtat cagctaatta caccataaag gtgcgcagtt
    65761 actcggcttt tcaagccgag tagctgtatg caagccccct agaagagccc actctttaca
    65821 aagtaaagta tagtatgtta tactttacat ggaagtagtc actgaattcc agttagaaat
    65881 tactttgtaa ctacgttttg aggaggagta aaatgctttc ctacgttcga cattacccac
    65941 tagcgatagc taaattaatg tgtctgtgct ctcctgaaat ctgctgattt attactgact
    66001 aatacaggag gtttttttta tgggacagac aatcatatct gctattggtg tttatatttc
    66061 caccagtatc gattatttaa ttattttaat tattttattt gcacagctat cacagaataa
    66121 acagaaatgg catatttatg cggggcaata tctaggcaca ggcttacttg taggggcgag
    66181 tttagttgct gcttatgtcg ttaatttcgt gcctgaagaa tggatggttg gattgcttgg
    66241 tttaatccct atctatttag ggattcgctt tgcaattgtt ggagaagatg cggaagaaga
    66301 agaggaagaa attattgaaa gattagaaca aagcaaggca aatcaactgt tttggacagt
    66361 tacattgctg acaattgcgt ctggcggaga taatttaggt atctatatac cttattttgc
    66421 ttcgttagat tggtcacaga ccctcgtggc cttgcttgtg tttgtaatcg gcataattat
    66481 cttttgcgag attagtcggg tgttatcctc tattccgtta atattcgaga caattgaaaa
    66541 atacgagcga atcattgtgc ccttagtatt cattctactt ggactataca tcatgtatga
    66601 aaatggcacg atagagactt ttctgatcgt gtagattttt ttgtttcact aggattttag
    66661 cccgagctca aatcagctct ctgattttca gagggctttt tcattgagta taaatggaca
    66721 atcttaaagt tactctattg tagagtggct tttgatttga ttaggagatt cttataaata
    66781 tagtaaaatg aaacaaaaac aggacaaatc gatcaggaca gtcaaatcga tttctaaaaa
    66841 tgttttaaga agtagaggtg tactattcta gtttcaattt gctatataaa tgaaaacctt
    66901 agctgtttgg ccaaggttca tttcttctat gcaagttctt ctcttttctt atctgggttc
    66961 cagatgaagc ttgcgataaa gctaaagatg atggttagga tagcgaggat aatagcaagg
    67021 atgagggcag ggatgcggat aaaccaccag agtggatttg gttttttatc attgtgccat
    67081 tgtttcgttt cttcgtccag acgttggaat tctgtttgaa tacgattggc gactgtttca
    67141 atgccttcat cattcatttt cttgatatct gagatatcga ttggatttcc aaagttcata
    67201 tcgacacgtt cacggctaat caagcccttc aaaatcatgg gaccggtgta ggtaaccggc
    67261 atgatacgga ccttggccat tttggcaatc agtgctgcgc cccccttgac atcgtttgag
    67321 tggcggctac cacttggaaa catgatgaga gagcggtcac tttttttgag aacgttgata
    67381 ggatatttga tggctgaggc gctgggattt tcacggtcga tgggaaaggc gccacacata
    67441 cgaatccacc aaccaaagat acggttggta aagagttctt tttttgccat aaagatgaac
    67501 tgttttggct tggtcgcaaa ggccatataa acaggatccc accaggtacg gtgaggcgca
    67561 actaaaatat aattttcatc ttgattagga attttatcag tattatgata gtgagcattg
    67621 ccattgatgg accataagag caacacaact aatccacgca aataagtata aaacatgcga
    67681 tctccttcga ttgttttctt gttattatta taccttatca aaggagggct ggcaaacttt
    67741 tcccttgact agatgcatat ttgggatgaa attagaattc tgttaaaaaa aatggtataa
    67801 tagaatttat ggataaaaat aagattatgg gattaaccca aagagaagtc aaggaaagac
    67861 aggctgaggg tttggtcaat gactttaccg catcagccag taccagcact tggcaaatcg
    67921 ttaaacgaaa tgtctttacc ctttttaacg ctttgaactt tgccattgct ttggcccttg
    67981 cctttgtgca ggcttggagc aatctggtct tctttgctgt tatctgcttt aacgcttttt
    68041 ctgggattgt gaccgagcta cgagccaaac acatggtgga caagctcaat ctcatgacca
    68101 aggaaaaggt caaaaccatc cgtgatggtc aggaagttgc tcttaatcct gaagaattag
    68161 tgctaggaga tgtcattcgt ttgtctgcag gagagcagat tcctagtgat gccttggttt
    68221 tggaaggctt tgcggaagtc aatgaagcca tgttaacggg agaaagtgat ttggtgcaaa
    68281 aggaagttga cggcttactt ttgtcaggaa gtttcctagc cagtgggtca gttttatctc
    68341 aagttcacca tgtcggtgca gacaactatg ctgccaaact catgcttgag gctaagaccg
    68401 ttaaacccat caactcccgt atcatgaaat cgctggacaa gttggctggt tttactggga
    68461 agattatcat tccctttggt ctggctctct tgctggaagc cttgctttta aaaggcctgc
    68521 ctctcaagtc atccgttgta aactcgtcga cagctctttt gggaatgttg cctaagggaa
    68581 ttgccctttt gaccattact tcgctcttga ctgcagtgat taagttgggc ttgaaaaagg
    68641 tcttggtgca ggagatgtac tctgttgaga ccttggcgcg cgtggatatg ctctgtctgg
    68701 acaagacggg caccatcacc caaggaaaga tgcaggtgga ggctgttctt ccactgacgg
    68761 aaacttacgg tgaagaggct attgccagca tcttgactag ctacatggcc catagtgagg
    68821 ataagaatcc aactgcccaa gccattcgcc agcgttttgt gggagatgtt gcttatccta
    68881 tgatttccaa tcttcccttc tcgagcgacc gcaagtgggg ggctatggag ttagaaggct
    68941 tggggacagt tttcttaggg gcacctgaga tgttgctgga ttctgaagtc ccagaagcca
    69001 gggaggcctt ggagagagga tcacgtgtct tggtcttagc tctcagtcag gagaaattag
    69061 accatcacaa accacagaaa ccatctgata ttcaggctct agccttgctg gaaatcttgg
    69121 accccattcg agagggagca gcagagacgc tggactatct ccgttctcag gaggtgggac
    69181 tcaagattat ctctggtgac aatccagtta cggtgtccag cattgcccag aaggctggtt
    69241 ttgcggacta tcacagctat gtagattgct caaaaatcac cgatgaggaa ttgatggcca
    69301 tggcggagga gacagctatt ttcggacgtg tttcccctca tcaaaagaaa ctcatcatcc
    69361 aaacgttgaa aaaagcgggt catacaacgg ctatgacagg ggacggggtt aatgatatct
    69421 tggcccttcg tgaggcggat tgttctatcg tgatggcgga gggggatcca gcaacccgtc
    69481 agattgccaa tctggttctc ttgaactcag actttaatga tgttcctgag attctcttcg
    69541 agggtcgtcg cgtggtcaat aacattgccc acatcgcccc gattttcttg ataaagacca
    69601 tctattcctt cctgttagca gtcatctgta ttgccagtgc tttactaggt cggtcagagt
    69661 ggattttgat tttccccttc attccgatcc agattaccat gattgaccag tttgtggaag
    69721 gtttcccacc attcgttctg acttttgagc gaaatatcaa acctgttgag ccaaatttcc
    69781 tcagaaaatc catgcttcgt gccctaccaa gcgctctcat ggtcgtcttc agcgtcctgt
    69841 ttgtgaaaat atttgggagt agccaaggtt ggtctgagtt agaaatctca actctactct
    69901 attatctctt ggggtcaatt ggtttcttat ccgtatttag agcctgcatg ccatttaccc
    69961 tatggcgtgt cctcttgatt gtttggtcag taggaggttt cctagccaca gctctcttcc
    70021 caagaattca aaaactgctt gaaatttcaa ccttaacagg acaaacatta cctgtttatg
    70081 gtgtcatgat gttggtcttt accgtgattt tcatcctgac cagtcgttac caagcgaaaa
    70141 aataaagaaa gactgcaatc tgtggattgc ggttttttta ggtacaagat tgccagccga
    70201 aatgtggtat aataagaggt aatagagttt ggaaagtgag agaaaatgat ttcaaagaga
    70261 ttagaattgg tagcttcctt tgtgtcacag ggggctattt tactagatgt gggaagtgac
    70321 catgcttatc tgcctatcga gttggttgag agaggccaaa tcaaaagcgc tattgcaggt
    70381 gaggtggtgg aaggtcccta tcagtctgcg gttaaaaatg ttgaggctca cggcctaaag
    70441 gagaaaatcc aagtccgttt agccaatggc ttggcagctt ttgaagagac tgaccaagtg
    70501 tctgtcatta ccattgctgg catgggtggt cgtttgattg ctaggatttt agaagaaggt
    70561 ttggggaagt tagctaatgt agagcgtttg atcctccagc ccaataatcg tgaagacgac
    70621 ttgcgtatct ggctacagga tcatggattc cagattgtag cagaaagcat cttagaagaa
    70681 gctggaaagt tttatgagat tttggtggtg gaagcaggac aaatgaagct atcagccagt
    70741 gatgttcgct ttggtccctt cttgtccaaa gaagtcagtc cagtatttgt ccaaaaatgg
    70801 caaaaagaag ctgagaagct agagttcgcc ctcggacaaa tcccagaaaa aaatctggaa
    70861 gaacgtcaag ttctagtaga taagattcaa gctatcaagg aggtgcccca tgttagcaag
    70921 tgaagtgatc caagcttatg aagccttttg ccctcaggaa ttttctatgg agggagacag
    70981 ccgtggtctg caaattggca ctttagacaa gggtatccaa agggtcatgg ttgccctcga
    71041 tattcgtgaa gagacagtgg cagaggccat tgaaaagggt gtggacttga ttatcgtcaa
    71101 gcacgcgcct atctttcgtc ctatcaagga cttgcttgcc agccgtccgc aaaatcagat
    71161 ttacatcgac ctgattaagc atgatatcgc agtttatgtc agccatacca atattgatat
    71221 cgttgaaaat gggctcaatg actggttttg tcagatgcta ggaatcgagg agacgactta
    71281 tctgcaggaa acaggtccag aacgtggaat tggacgtatt gggaatattc agcctcagac
    71341 attttgggaa ttggcccaac aggtcaagca agtctttgac ctagatagcc ttcgaatggt
    71401 gcattatcaa gagaatgatt tgcagaagcc tatttcaaga gtagcaattt gtggtggaag
    71461 cgggcagtct ttctataagg atgctttggc aaagggggca gatgtctata tcactggtga
    71521 tatctactac catactgctc aggatatgct gtctgatggc ttgttagcat tggatccagg
    71581 tcactatatc gaagtgcttt ttgtggaaaa aatcgcagca ctccttactc aatggaaaga
    71641 gaaaaaaggc tgggaactag agattttacc tagtcaagca tcgaccaatc ctttccgtca
    71701 tatctagtta gaaagtgaag acaatgaaaa aagttgccat tattggagca ggaattgtgg
    71761 gagcaacagc tgcctactac ctctcgagag aaagtgacct agaggtgacc gtttttgacc
    71821 atgagcaagg tcaagccacc aaggccgcag caggaattat cagtccttgg ctttcaaaac
    71881 gccgcaataa ggcctggtac aagatggcgc gattgggggc tgacttttat gtggatttat
    71941 tagctgattt agagaaatca ggacaagaaa tcgactttta ccagcgttcg ggagtctttc
    72001 tcttgaaaaa ggatgaatcc aagttggaag aactctatca actggctctc cagcgcagag
    72061 aagaatctcc cttgataggc cagttatcca ttctggacca agccccagct aatgaattat
    72121 tccctggctt gcagggattc gacaacttgc tctatgcttc tggtggagcg agagtagatg
    72181 gtcacctctt agtaactcgt ttgctggaag ccagtcaggt caagttggtc aaagaaaaag
    72241 tgactctgac actcttatca tcaggctacc agattggcga agaggtgttt gatcaggtta
    72301 ttttggcaac gggagcttgg ttgggggaca tgttagagcc tttaggttat gaagtggatg
    72361 tccgtcctca aaaaggacaa ctacgagatt atcagcttgc ccaagacatg gaagattacc
    72421 ctgttgtcat gccagaaggg gagtgggatt tgattccctt tgcaggtggg aaattatcct
    72481 tgggcgctac ccatgaaaat gacatgggat ttgatttgac ggtagatgaa cccttgctcc
    72541 aacaaatgga ggaggcggcc ttgcctcatt acccagtttt agctagagtg acttcaaggg
    72601 ctgagcgtgt gggaatccgt gcctatacca gtgatttctc tcccttcttt gggcaggtgc
    72661 cagaattggc aggtgtctat gcagccagtg gactaggttc atcaggcctc acaactggtc
    72721 ctatcattgg ttaccatcta gcccaactga tccaagacaa ggagttgacc ttggaccctg
    72781 aaaactaccc aattgaaaac tatgtcaaac gagtaaaaag cgaataatac tcaatgaaaa
    72841 tcaaagaaca aactaggaaa ctagccgcgg attactcaaa gcactgcttt gaggttgtgg
    72901 atagaactga cgaagtcagc tcaaaacact gttttgaggt tgtggataga actgacgaag
    72961 tcagtaacca tacccatggc aaggcgacgt tgacgtggtt tgaattggat tttcgaagag
    73021 tataagcatt ttactgaaat tttatcaggt agtttaggat ggcaaatgac attccctgtc
    73081 aaaaatggta aaataagaaa aaataatctg agaatcgagg aaaaaagatg caagaaaaga
    73141 ttttggtaac tggtggtgcc ggttttattg gaacccacac tgttattgaa ttgatccaag
    73201 caggccatca agttgttgtg gtggataatc ttgtcaatag caatcgtaag agtttagaag
    73261 ttgttgaaag aatcacagga gttgagattc ctttctatga ggcagatatt cgtgacacag
    73321 ataccctcag agatattttc aagcaggaag aaccgactgg tatcattcac tttgctggtt
    73381 tgaaggctgt tggcgaatca acacgtatcc ctcttgccta ctatgacaac aatatcgctg
    73441 gaactgtcag ccttttgaaa gccatggaag aaaacaactg taaaaacatc atcttcagtt
    73501 cttctgcgac agtttacggg gatccgcaca cagtgcccat cttggaagat ttcccacttt
    73561 cagtgaccaa cccatacggt cgtactaagc tcatgctaga ggaaattttg actgatattt
    73621 acaaagcaga ctcagaatgg aatgttgtct tgcttcgtta ctttaaccca atcggagccc
    73681 atgagagtgg tgatttggga gaaaatccaa acggtattcc aaacaatctc ttgccatatg
    73741 tgactcaagt agccgttgga aaattagagc aagtgcaagt gtttggagac gattacgata
    73801 cggaagatgg aacaggtgtt cgtgattata tccacgttgt cgatttggct aagggtcacg
    73861 ttgcagcttt gaaaaaaatc caaaaaggtt caggactaaa cgtttataac cttggaactg
    73921 gtaaaggtta ctcagttctt gaaattatcc aaaacatgga aaaagcggtg ggacgtccta
    73981 ttccttaccg catcgtagaa cgtcgcccag gtgatatcgc tgcctgctac tcagacccag
    74041 caaaagctaa agcagaactc ggttgggaag cagaactcga catcacccaa atgtgtgaag
    74101 acgcatggcg ttggcaaagc aagcatccaa atggatttga agactaagat gatgatttca
    74161 atcatcgtcc cttgtttaaa cgaagaggaa gtacttcctc ttttttatca ggctctggaa
    74221 gctttacttc cagatttgga aacagaaatc gagtatgtct ttgtcgatga tggatcaagt
    74281 gatgggacct tggaactctt aaaggcctat cgggagcaaa atccggcagt ccattatatt
    74341 tctttctctc gaaattttgg caaagaagca gccctttatg caggcttgca atatgcgaca
    74401 ggagatttgg tggtggtgat ggatgcagac ctccaagatc ctcctagtat gttgtttgag
    74461 atgaaaaatg tactagacaa aaatgtagac ttggactgcg ttgggacacg gagaactagt
    74521 cgggagggag aacccttctt tcgcagtttc tgtgctgttc tcttttatcg cctcatgcaa
    74581 aaaatcagcc cagtagctct gccgtcgggt gtccgtgatt ttcgtatgat gagaaggtct
    74641 gtagtcgatg ccattttaag cttgaccgag tccaatcgtt tttcaaaggg gctcttcgcc
    74701 tgggtgggtt tcaaaaccta ctatttggac tatccaaatg tcgaaaggca ggctggcaag
    74761 acaagttgga gttttaggca actctttttc tactccattg aagggattat taatttttca
    74821 gattttccct tgattatagc ctttgtagct ggtctcctat cttgttttct ttctctgctg
    74881 atgacctttt ttgttgtggt tcggaccctc attttgggca atccgacatc tggttggacc
    74941 tctctgatgg ctgttattct ctttcttgga ggcattcaac tcttgaccat tgggattctc
    75001 ggcaagtata tcagtaagat ttatttagag actaaaaaaa gaccacttta tcttatcaaa
    75061 gaaaaaagtg accttcctga ttttacagaa aaaaataaag tgaaaagact ataattttac
    75121 atggaaatgt gctaaactag agggagtgga ttatcgccat tgatttaggc ttcctggttt
    75181 ccaatcaggg cgcgcgttgg gcaattttta acagcctcta agacatcctg actaggagaa
    75241 atttcttttt ccagttggtc agggtcatcg taaaaacgca cgattccatt atcgtggtaa
    75301 tcaaataaat cagaataagt ttggcaaagc ccacaggcga tacatcgttc aggtataagt
    75361 gtgattttca tgttcatatt tatattgtaa taagaaaagt aaaaaaaaac aaggagtaag
    75421 gtatggcaaa agaaccgtgg caagaagata tctatgatca agaagaatca agagcagagc
    75481 gtcggcatcg aaaccacgga ggggctgata ggatggctaa tcgtattttg acgatcctag
    75541 ctagtatttt ctttgtaatt gtggtggtga tggtcatcgt tctcatctat ctatcatcgg
    75601 ggggaagtaa tcgcacagca gccttaaaag actttcatga ttctgatgca agtgtagtac
    75661 aaatctcatc ttcaagcagt tctcagcctg agcagagttc agagccagaa tctacttcta
    75721 gtagttcaga agaagctgct aatcctgaag gaacgattaa agttctcgca ggagaagggg
    75781 aagcagctat tgccgctcgt gcaggaatct ccattgctca gttagaggcc ttgaatcctg
    75841 ggcacatggc tacaggatct tggtttgcta atccaggtga tgttataaaa ataaaatagg
    75901 agccgatatg aaaacaattc aaattgctat tgatggtcct gcttccagcg gtaagagtac
    75961 ggtcgcaaag attattgcta aggattttgg attcacctac cttgatacag gagctatgta
    76021 tcgtgcagcg acctatatgg ctcttaagaa ccaattagga gttgaagaag tcgaagccct
    76081 tctagccttg ttggaccagc atccaatcag ctttggacgt tcagaaactg gagaccagct
    76141 tgtttttgta ggagatgtgg atattaccca tcctatccgt gaaaatgaag tgaccaatca
    76201 tgtttctgct attgcagcaa ttcctgaagt gcgtgagaaa ctggtttctc tccaacaaga
    76261 aattgcccag caaggcggga ttgtcatgga tggtcgcgat attggaactg ttgtattgcc
    76321 acaagcagaa ttgaaaattt tcctagtagc ttctgttgat gagagagcag agcgtcgtta
    76381 caaggaaaat attgccaagg gaattgaaac agaccttgaa accctaaaaa aggaaattgc
    76441 tgcgcgtgac tacaaggata gtcatcgtga gacttctcct ctcaaacaag cagaggatgc
    76501 tgtctacctt gatacaactg gtttgaacat tcaagaagta gttgaaaaaa tcaaagcaga
    76561 agctgaaaaa agaatgtaaa tgtagaaaag ccgatagatt gatatcggtt ttttctaaat
    76621 ttgtcaaaat gctgatttta gggtataata gttgctgttc gagaaatttt gattttcaaa
    76681 gaatagtgaa tgatgataag gagaaatcat gaacaattta ccaaattgtc caaaatgtaa
    76741 ctcagagtat gtctacgaag acggtgccct actggtttgc ccagagtgtg ctcatgagtg
    76801 gaatcctgct gaagttgcag aagtagaaga aggtcttgtc gctatcgatg ccaacggaaa
    76861 taaattggct gatggtgata cagtaactct catcaaggac ttgaaagtaa aaggtgcgcc
    76921 aaaagatttg aaacaaggga cgcgcgtgaa aaatatccac atcgtagaag gcgaccacaa
    76981 tatcgactgt aagattgatg gttttggtgc catgaaactt aaatcagagt ttgtgaggaa
    77041 gatttaagca tgtcaaaaca ctataaactt gtattttata gccgtatctt cttgtttcta
    77101 gcggctttta cgggagttta tcttgaaatt actaagcatg gtggttttgg gatgcttctc
    77161 tattacacgg ttctgtccaa cctcttggta actattttta ccctttatct tctaaaggtt
    77221 atgagccgtg taggtgaaaa ttggcaaaga ccaagtctct tgcgcttaaa aggtggggtc
    77281 accatgagta tcatgattac ctgtgtgatt taccatttcc tcttggcgcc cattgcgact
    77341 aatttctata ccctagaaaa tttcctttgc cactatatcg ttcccatctg gtttttagcg
    77401 gataccctct tttttgacaa acagggtcaa tacaagattt gggatccagc agtgtggacc
    77461 attttaccct ttctgtatat gatgtttgct ctttttaatg gcttggttct aaaactcaat
    77521 attccaaatg ccaaggataa tcctttccct tacttctttt tgaatgtgaa caagggttgg
    77581 aatgttgtgt ttaagtggtg tctgattatc tttgttgcct atatggtagc aggatttatt
    77641 ttctacttta tcaagcaaat caagagaaag tcatcctaat actcttcgaa aatctcttca
    77701 aaccacgtca gtttccatct gcaacctcaa aacactgttt tgaacaacct gcggctagct
    77761 tcctagtttg ctctttgatt ttcattgagt ataagataca agggattcat tttcgaattt
    77821 aagaaggagt ctacaaacca atgaggcttc ttcttttctt gcttatttga taactatcaa
    77881 aaaagtagaa gattaagaga aatatagaaa gagatttcat gaaacaattt ttagaacggg
    77941 ccagcatttt ggctctctcc ctcgttttga ttacctcctt ttccatttcg agtgccctac
    78001 cagccatgtt tgactattat cagggttatt ctaaggaaca aattgagctc ttggtgagct
    78061 tgccttcctt tggaatcatg atgatgttac tgctaaatgg tttcttagaa aaaatatttc
    78121 ctgagcgctt acagattagt ttgggcttgc tgattttatc attgagcggt acagctccct
    78181 tctggtacca agcctatccc tttgtctttg gagcacggct tctctttggt ttgggtcttg
    78241 ggatgatcaa tgccaaggcc atttctatta tcagtgaacg ctaccaagga aaaaggcgaa
    78301 ttcagatgtt agggctacgc gcttctgcag aggtcgttgg agcttctctc attaccttgg
    78361 ccgtcggtca gttgttggcc tttggttgga cagctatctt tctagcctat agtgctggat
    78421 ttttggtgct gcccctttat ctgctctttg tcccttatgg aaaatcaaag aaagaagtca
    78481 agaaaagagc gaaggaagca agtcgtttaa ctcgagaaat gaaaggcttg atttttacct
    78541 tagctatcga agcggcagtt gtagtttgta ccaatacagc tattaccatc cgtattccaa
    78601 gtttgatggt ggaaagagga ttgggggatg cccagttatc tagttttgtt cttagtatca
    78661 tgcagttgat cgggattgtg gctggggtga gtttttcttt cttgatttct atctttaaag
    78721 agaaactgct cctctggtct ggtattacct ttggcttggg gcaaattgtg attgccttgt
    78781 cttcatcctt gtgggtggta gtagcaggaa gtgttctggc tggatttgcc tatagtgtag
    78841 tcttgacgac ggtctttcaa cttgtctctg aacgaattcc agctaaactc ctcaatcaag
    78901 caacttcatt tgctgtatta ggctgtagtt tcggagcctt tacgacccca tttgttctag
    78961 gtgcaattgg cttactaact cacaatggga tgttggtctt tagtatctta ggaggttggt
    79021 tgattgtaat ctctatcttt gtcatgtacc tacttcagaa gagagcttag gattgattcc
    79081 taagtttttc ttttgatact caatgaaaat caaagagcaa actatagttg attgagtttg
    79141 gaatagtacg ctgtagctgc taaaatattt ctagaaatta atttgacttt cctaatagag
    79201 ttattcatat cttatttcaa tctactatag aaagctagcc gcaggttgct caaaatagtg
    79261 ttttgaggtt gcagatggaa actgacgtgg tttgaagaga ttttcgaaga gtatgagatt
    79321 tttataccca tacaatattt gttttaggtc cttgtttaca gactaatttc ttgataaaat
    79381 agaggttatg acgagatata aagcaactat ttcctatgat ggttatgcct ttgctggctt
    79441 tcagcgccag tctcatgcgc gtagcgttca ggaagaaatt gaaaaaacct tgaccagatt
    79501 aaataaaggg caagccatta ctgttcacgg tgctggtagg acagatagtg gggttcatgc
    79561 cctgggacag gtcattcatt ttgacctgcc ttatcagatt gatgaggaga aactccgttt
    79621 tgccttggat acccagtctc ctgaagatat tgatgtgatt tcgattgagc ttgtggcaga
    79681 tgattttcat tgccgttatg ccaagcatag caagacctat gagtttattg tggatagagg
    79741 acgtcccaaa aatccgatgc gccgtcacta tgccacccac tttccctacc cactcgatgt
    79801 ggaacgaatg cagattgcaa tcaaaaagct agagggaacc catgatttta ccggttttac
    79861 agcctctggg actagtgtag aggataaggt tcgcaccatc acagaagcta gtttaatagt
    79921 cgatgagaca ggacaatttt tgacctttac cttttccgga aatggtttct tgtataaaca
    79981 gattcgcaat atggtgggga ctcttctcaa aatcggtaac aaccgcatgc cagtagagca
    80041 gattgatctc atcttggaga agaaggacag gcaacttgca ggtcccactg cagcaccaaa
    80101 tggtttgtat ttaaaggaga ttcgttatga agaataatcg tattttagca ctttctggaa
    80161 atgatatttt tagtggtggt ggactgtcag ctgatttggc tacctatacc ttgaacggct
    80221 tgcatgggtt tgtagcagtg acttgtttga cagccttgac agaaaaagga tttgaagtct
    80281 ttccaactga tgataccatt tttcaacatg aattagatag cttgcgtgat gtggaatttg
    80341 ggggaattaa gattggtctt ctccctactg tcagtgtggc tgagaaggcc ttggacttta
    80401 tcaaacaacg cccaggagta cctgtggtgt tggatcctgt cttggtctgc aaggaaacgc
    80461 atgatgtagc tgtcagtgag ctctgccaag agttgattcg ctttttccct tatgtcagtg
    80521 tgattacgcc taatctccca gaagcagaat tattatccgg tcaggaaatt aaaaccttgg
    80581 aagacatgaa aactgcagcg cagaaattgc atgatttagg agcgccagca gtcattatca
    80641 agggaggcaa tcgtcttagt caggacaagg ctgtggatgt cttttatgat ggacagacct
    80701 ttactatcct agaaaatcca gttatccaag gccaaaatgc tggtgcaggt tgtacctttg
    80761 cctctagcat tgccagtcac ttgattaaag gtgataaact tttgccagca gtagaaagct
    80821 ctaaggcttt cgtttatcgt gctattgcac aagcagatca gtatggagta agacaatatg
    80881 aagcaaacaa aaacaactaa aatcgccctt gtatccctat taaccgccct ttctgtggtt
    80941 ctaggttatt tcttaaaaat cccaacacct acaggaattc taactctttt agatgctggt
    81001 gtcttctttg cggcctttta ctttggtagt cgtgaaggag cggtagtcgg aggactagca
    81061 agtttcttga ttgacctctt atcaggctac cctcagtgga tgttctttag cttggtcaac
    81121 catggcttgc agggattttt cgcaggattt aaaggaaaaa gtcagtggtt aggccttatt
    81181 ttagcaacta ttgccatggt aggaggctac gccttgggtt ctactttgat gaatggctgg
    81241 gcagcagccc tcccagaaat tctaccaaat ttcatgcaaa atatggtagg gatgattgta
    81301 ggatttattc ttagtcaaag tatcaagaag attaagtaat actcttcgaa aatctcttca
    81361 aaccacgtca gtttccatct gcaacctcaa aacactgttt tgagcagcct gcggctagct
    81421 ttctagtctg attttcattg agcataaaga ggttgagtaa aaagtctttc aaataagaaa
    81481 aacgcatagt atcaggtgtt gaatgaacac ctgatactat gcgttttatt gtgggaagat
    81541 tttcctcatt ttctagtgaa attgaacttt ttctaacatc ttttgataga tgacttctta
    81601 atcaattatc atttccattg ttgtttcttg gggtttcatc ccttgtcttt gataaaagcg
    81661 gagagcaccc tcgttatcat tccagacact tagggttaga ttattgcagc caatttcttt
    81721 agcataatag cagaaaaatg acaataaaat agcccctaga tattttgaaa ggaaagcata
    81781 ggggctatat agtttaatca aaataaagca aatctttgct ggtgcttgta aagaggtcga
    81841 agccatcctt ggtaacaaca ccgcagtctt caatacgaac accgacttta ccagggatat
    81901 agatacctgg ttcaacagag aagcacatgc cttcttcgat gaccatgtcg tttccttcca
    81961 tgatagatgg gaattcatgg acatccatac cgataccatg cccgagacgg tggttgaagt
    82021 actcaccata accagctttt tcgatgacct cacgggcagc gcggtccact tcatgagcag
    82081 tcacacctgg cttgataaag tcaagagcag cttgttgggc ttcaagagtc aagttgtaaa
    82141 tatctttctt gaattggtct ggtttgccga cagcgactgt acgagtcata tctgacgcat
    82201 agccattgac cagaacaccc aggtcaaaga ggagaagagc atcattttca accttattag
    82261 ctgctggaat gccgtgtgga ttcgcagcat tatcaccagt caagaccatg gtatcaaagc
    82321 tcatttcgta accttcacgt ttcatggcaa agtcaatttg tgcgatgata tctgtctcag
    82381 tcttatcaag agaaatattg tcaaaaccaa catgaacagc cttgtcagca taaagacctg
    82441 caaccatcat tttttgcact tcatcagctg atttgatgag gcgcatgcgt tggatacgag
    82501 gagtgaggtt gtcaaactca gcagtctcaa aaactgtttt caaaccatgg tatttggtca
    82561 agatgagatt gtcaaactca acagcgacac gtttgaagtc aagttgtgga agagcatgtt
    82621 tgattttttg ccatggattt tcagaatcga catagcccac tactgggaag gaaacggtgc
    82681 tacttgcacg ttctacttca agagctggga caaagaggag aggttcctga tctgctagga
    82741 caaagaggaa catttggcgt tcatggggat cactgtaaaa accagtgagg taattgattg
    82801 tgacggggtc agatacgaca gcgacgtcta gtttttctga ttcaagatat gttaggattt
    82861 gttgtaattt agacatatgc taccttcttt ctatccctct attttggcaa aaaatgagag
    82921 aaaatgcaag ggagaagggt aaaagaaaag acaaaaaact ccgacaagat aacggagttc
    82981 tttgatatca ttttcctttg tttaagaaaa gtcagccttg cttttgacgt cactgtactc
    83041 ttcagcgatt tcttggctga ggatatcctc ataggcaggg agttggatgt cctgaccata
    83101 tttcttcttg agggcagtag taactaggcg ataagccaga ttggcattac gagagaggat
    83161 aggcccgtgg aagtaggaac caaagacatt cttataatga accccttcac cgaccttttc
    83221 ttcgttgttt ccatttccat agacaacctg tcccagcggt ttttggtcat cagagaggaa
    83281 ggtacggcct tggtgatttt caaatccata gtaggtttca tcgaaatctt cattgtgaat
    83341 cttgatgtca ccgataaaac ggttattggt ctggttgagc gtgtagtgtc ccatgacccc
    83401 tagcccttcg atacgttttc ctgaagcttc aacataatat tgacccaata gttggaaacc
    83461 accgcagata gccagaacta caccgtcgtt ttggatgtag ttgtcaatgc tctctttttt
    83521 agcaggtagg tcgtctgcaa tgatactttg ttcaaagtct tgaccaccac cgaaaaaggc
    83581 gatgtcgtag tgattttcat caaagtcatc atggagagaa acgatgtcaa cggtcacatg
    83641 ggctcccagt ttttcagcca catacttgag catgaggatg tttccattgt ccccgtaggt
    83701 attcatgaga tttccgtaga ggtgggcaat gttgagctga taggggtaat tgccatcttt
    83761 tgaggaaagt gaagtataaa ccattagttc atctcctttc taacaatctg acgactagcc
    83821 agcagttcac gaaattccag catggcagta taagttgcca gaatataggc atgcttgcag
    83881 tcttgattct caatggtctt gagaacttgc tccagattac tcgtttcagt gattttctca
    83941 gctggatagc cagtcactcg gaggcgacga gcgatttcag aatgacgaac accgccagcg
    84001 ttgatttcag gaatgtccat gtcagtgatt tgttcaaagt ctgcatccca gatccagcta
    84061 gtgtcaattc catctgcata gttggcatta aggaggacag ataggctaaa tggataaggt
    84121 gctagtttga tcatttcgat agcttgggtt gcaccgactg gatttttaat caagacaagg
    84181 gtacattcct tgtcaccgat atgaaaggtt tcttggcgtc caaagacagc acggctcttg
    84241 tcaaatccct gtttgatgag ttgcgaatcg gcacctagga aacgggcgat ggccacagca
    84301 gctagggcgt tatagatatt atagagcccg ccgatttgga taccgtattc ttggacgtct
    84361 atgacaaagc gagagcgatt gttggtcaac tcaaccagtt ttgtcaaacg atagtcgaga
    84421 tcaggacgtt tacatccaca accttcacag atataggtac ccaagtttgc ataggtatta
    84481 tgctcatatt tgaggatgcc ttggcagtca ggacagagaa tcccttcggt attgtagtga
    84541 gccagttggg ctggtccttt ttccaagtca aaaccaaaat actctatagg gtttggaata
    84601 gttggcttgt agaaaagtgg actgtctccg ttaaggagaa cagtagcagt tggaactttc
    84661 cgaatggcat ccaatatcat gttataggta gtatagattt caccgaaacg gtccatctgg
    84721 tcacggaaga tattagtaat gacaaaaaga ctaggctgga tatagtcaca gatacgagat
    84781 agactggctt cgtcaatttc gaggacggca atattttttc cagttttaga agatttggct
    84841 gttaggaagg ttgttgcaat ccctgtaatc atgttggcac cgcttggatt ggttagaact
    84901 tgaccataga cctcttttaa aatgccgaca gtgagggcag ttgtcagggt ttttccattt
    84961 gttccagtga caacgacaat ctcgtagttc ttagctaggt tttgtaaaat atctttatca
    85021 aattgaaggg cgactttacc tgggagcgta cttccacggc caagacggct taaaatgaag
    85081 tgggaagaac gcccagcaag aaggcccaaa gtagttttta agttcatgtt tctattatat
    85141 cataaaagag gagaaagaca gatttgagat tccgcagaag taaaaacagc ccaaagaggg
    85201 ctgttcgata cgattaaatc tcaacttaaa tcgcaaacaa gtcattcaag ttctcagcca
    85261 aggttgggtg agtgaagatt tgttttgtga agtaagtgta aggaatcttg ttgtccatag
    85321 caacagtgat gatgttgatg atttcttgag aaccttctga gaagatgctt gctccaagaa
    85381 tttcttttgt ttcagtattg acaacagctt tgaaggcacc gcgaaggtct ccatttacgt
    85441 gaccacgagg catggctgca acggggattt ccttaacagc gtatggaagt ttcaaatcag
    85501 ctgcttggct ttcagtcaaa ccaacttgtg aaagtgcagg tgtgatgaac atagtatttg
    85561 gcacattgag acggtcttca agtgtgtagc tgccatctcc agcaaggtag ctgtaaacaa
    85621 cacggaagtc atcaagtgaa atgtaagtaa attgaaggcc accgttgata tctccaactg
    85681 caaagacacc aggaacgttt gtttgacagt gtttgtctac tttaatagca ccacgttcag
    85741 ttagttcaat atctgtattt tcaagttgaa gtggttctac atttggtttg cgtccagttg
    85801 cgtagagaag ggcgtcgaaa cggtaagttt cgtcttcagt tacgacaagc acttggtcac
    85861 catcgttttt gatttcagta gtatggatat tttgaagcaa ttcaatgcca tcttcttcca
    85921 tgtattgttt agcaagagct gcgatggaag gttctgcacg aggaaggaaa gtatccaagg
    85981 catctaggac tgtgaccttg cttccaagtt tgttgtaaag gccggcaaat tcaagaccga
    86041 tatttccgcc accaaggatt ccaagttttt caggtaattt gtccaagttt tggatacctg
    86101 ttgagtcaaa gatgtttttg cttgtagcaa gtccagggat tggcaagacg tttgaaacag
    86161 caccagtgtt gatgacgatt gtttcagcag tcagttcttt cttttcatca ccagcttgga
    86221 tttcgatgac tttatttgaa aggaagtgag cttccgcatc aaagatatct acgcctgtac
    86281 cagcaacagt cgcatagttt ttaccgttga ggcgaccagt gatcgtgttt ttagtagcaa
    86341 tcacttcttc aaaagacaag tccttttcag cagcaactag caaggtttta gttgggatac
    86401 aaccaatgtt gatacaagtt ccaccgtaca tagccttgct gcgttcaacg agggcaactt
    86461 ttttgccagc tgaagccaat ttacctgcta gtgttttacc agctttacca aatccaataa
    86521 caattaaatc gtatgttaac atttatcttc ctcctattcg aatttcattc tagcacaaga
    86581 aaaaaacttt tgcacaattc tgctacggaa aagacagaaa aagataaaaa cgctttccag
    86641 acaaaaaact agtaattttt tgacaagctt gataaactaa aatcctatct atttttatat
    86701 aagatagaat aaatgttcga aaataggagg ttttatgaaa tcgaatcgtt atattattgc
    86761 ctttgctggg gtcattttac acttaatgct gggttcgact tatgcttgga gtgtttatcg
    86821 taaccctatt attgaaaaaa cgggatggga tcaggcttct gttgcctttg cctttagtct
    86881 agcaatcttt tgtttgggct tatcggctgc atttatgggg cgtttggtag aaaaatttgg
    86941 tccgagagtc atggggagtc tatctgcttt tctatacgca ggtggaaata tcttaacagg
    87001 atttgcaata gaccgtcagg agctgtggtt gttgtatctc gcttatggca ttttaggtgg
    87061 gcttggtttg ggagcaggct atattacccc tgtgtcgacg attataaaat ggtttcctga
    87121 taaacgtggt ctcgcaacag gtttagcgat tatggggttt ggttttgctt ctttattgac
    87181 tagtcccata gcgcaacacc tcatcgcagg ggtagggctt gtagaaactt tttatatttt
    87241 aggagcaagt tactttatta tcatgctcct agcttcacaa ttcattaagc gtccaaatga
    87301 gcaagagctt gcaattttat cttcttcagg gaaagaaaaa acagcctctt tgacgcaagg
    87361 aatggctgca aatcaggctc taaaaagcaa tcggttttat atactttgga ttattttctt
    87421 tatcaacata gcttgtggtt taggcttaat ttcagcggca tcgccaatgg cacaggagat
    87481 ggctggcttg tctacaagtc atgcagcagt aatggtgggc gttttaggga ttttcaatgg
    87541 atttggtcgc ttgctctggg cgagcttatc tgactatatc ggtcgccctc taacctttag
    87601 tatattactg cttgttaatc ttttcttttc tctctcactt tggctcttta cagattccgt
    87661 tttatttgta gtcgctatgt ctattttgat gacttgctat ggagctggtt tttcattgat
    87721 cccagcttat ctcagtgata tttttggaac caaggaattg gccgctctgc atggatatat
    87781 tttaacagct tgggcaatgg ctggtttagc gggacctatt ttattagcag agacttataa
    87841 aatggctcat tcgtacacac aaaccttgtt cgtttttctc attttataca gtatcgcctt
    87901 ggctttgtct tattatctag gtcgttcaat caaaaaagaa agtcaaaaac cgcttacatg
    87961 attttctgta gaaatggggc tatcttttgc tctggtcttg tgttatacta gataggttgc
    88021 aaagaaaaca gtacttttct tttgtggaaa agaagcaaca cgattttata tctagttata
    88081 tgaaaatacg tcataaaaag aaaagtataa actaagccct atagggtggc ttcgcaccac
    88141 ctttagaaag aagaataacg tgaaatttaa tgaattaaac ttgtctgctg atttgctggc
    88201 agaaattgaa aaagctggtt ttgtagaagc tagtcctatc caagaacaaa ctattccttt
    88261 ggcccttgaa ggcaaggatg ttatcggtca agctcagact ggtacaggaa aaactgcagc
    88321 ctttggcttg cctacccttg aaaaaatccg tacagaagaa gcgactatcc aagccttggt
    88381 catcgctcca actcgtgaac tagctgtcca aagtcaagaa gaactcttcc gctttggtcg
    88441 tagtaaggga gtcaaagtcc gttcagtata tggcggatca agcattgaaa aacaaattaa
    88501 ggctcttaaa tctggtgccc atatcgtggt gggaactcca ggtcgcctct tggacttgat
    88561 taaacgcaag gccttgaaat tacaaaacat tgaaaccctt atccttgacg aagcggatga
    88621 aatgcttaac atgggcttcc ttgaagacat cgaagccatt atttcccgtg tacctgagaa
    88681 ccgtcaaact ttgcttttct cagcaactat gccagatgcc atcaaacgta tcggtgttca
    88741 gtttatgaaa gcccctgaac atgtcaagat tgcagctaag gaattgacaa cagaattggt
    88801 tgaccagtac tatatccgtg ttaaggaaca agaaaaattt gacaccatga ctcgtctcat
    88861 ggatgtggca caaccagaac tcgctattgt atttggtcgt accaaacgcc gtgtggatga
    88921 attgactcgt ggtttgaaaa ttcgtggctt ccgtgcagaa ggaattcatg gcgacctaga
    88981 ccaaaacaaa cgtcttcgtg tccttcgtga ctttaaaaat ggcaatcttg atgttttggt
    89041 tgcgacagac gttgcagcgc gtggtttgga tatttcaggt gtgacccatg tctacaacta
    89101 cgatattcca caagatcctg agagttatgt tcaccgtatc ggtcgtacag gtcgtgctgg
    89161 taagtcaggt caatctatta cttttgttgc tccaaacgaa atgggttacc ttcaaatcat
    89221 tgaaaacttg actaagaaac gcatgaaagg tctcaaacct gcaagtgtag aagaatcctt
    89281 ccaatcaaaa aaacaggtag ctctcaagaa aatcgaacgt gattttgcag atgaaaccat
    89341 tcgtgccaac tttgagaaat ttggtaagga tgctcgcaaa ttggctgctg agtttactcc
    89401 agaagaattg gcaatgtata tcttgagtct gacagtccaa gacccagata gccttccaga
    89461 agtggagatt gcacgtgaaa aaccactacc gtttaaacca tcaggtaatg gtttcggtgg
    89521 taaagctaag ggaggtcgtg gaggccgtcg tggggacgac cgtcgagagc gtgatcgccg
    89581 tggcaatggt cgccgtgatg agttcaaaaa aggaagtcgt ggcaacgatc gttttgataa
    89641 ggaaaaacgt taccgtaagg ataataaaaa accacgcaat actttaagcg aaaagcaaac
    89701 aggctttgtt attcgtaaca aaggcgataa ataagaaaaa gcggttcaaa atgaatcgct
    89761 tttttatata aggagaccga atgtgaaaag acaaataaaa ttattatatt atcttttata
    89821 atgttatgat acacaaaaat aggcaacttg tcaatagaaa aggaacaatt taattaaaaa
    89881 tattctggtt tttaattaaa ttgtaagtca atgcaagtca ataaggaatt ttcagataat
    89941 tattgaaaaa gagacgtttt tatgttataa tgatagcgat taaattcgag gtgaaaaatg
    90001 gcacatttat tagaaaaaac tagaaaaatt acatcaattt tgaaacgctc agaggagcag
    90061 ttgcaggatg agctccctta caacgctatt acgcgtcagt tagcggatat tattcattgc
    90121 aatgcctgca ttatcaatag taagggacgt ctgcttggct attttatgcg ttataaaaca
    90181 aatacagatc gcgtagagca attcttccaa actaagattt tcccagatga ctacgttcaa
    90241 ggggctaata tgatttacga aacagaagca aacttgcctg ttgagcatga tatgagtatt
    90301 ttccctgttg agagtagaga tgattttcca gatggcttga cgactattgc accgattcat
    90361 gtatcgggga ttcgccttgg ttctttgatt atttggcgta atgataaaaa attcgaagat
    90421 gaggacttgg ttcttgttga gattgccagt accgttgttg ggattcagct tcttaacttc
    90481 caacgtgaag aagatgagaa aaatattcgt cgtcgtactg ctgtcaccat ggcggtcaat
    90541 accctttctt actccgaact ccgtgctgtt tcagcaattt taggggaatt aaatggaaat
    90601 gaagggcagt tgactgcgtc agtgattgca gatcgtatcg gaatcactcg ctctgtgatt
    90661 gtcaatgctc ttcgtaaact tgagtctgcg gggattattg aaagtcgctc acttggaatg
    90721 aagggaacct atcttaaggt cttgatttca gatatttttg aagaagtgaa gaaaagagat
    90781 tactaatgac aaaggcttta atttcgattg attatacaga agattttgtt gctgatagtg
    90841 ggaagctgac agcaggtgct ccagctcagg cgatttcgga tgccattagc aaggtaactc
    90901 gattagcttt tgaacgagga gattatatct tctttactat tgatgctcat gaagaaaacg
    90961 attttttcca tccggaaagt aagttatttc ctcctcataa tctgattggg acgagtggac
    91021 ggaatttata tggagatttg gggatctttt atcaagagca tggttcagac agtcgtgtct
    91081 tttggatgga taaacgccat tactcagctt tttcagggac tgacctagat attcgtttga
    91141 gagagcgtag agtgtctacc gttatcttaa caggtgtctt gacggatatc tgtgtcctac
    91201 atacagctat agatgcctat aatctaggat atgacatcga gattgttaaa ccagctgttg
    91261 cttccatctg gcctgaaaat catcaatttg ccctaggtca tttcaaaaat acactcggag
    91321 ctaagttagt agatgaaaat ctaaatgaac tttctgagta acctggttgg tgaaaatgaa
    91381 aaaatttgaa aaaaagtgtt gacaagcatc ccaaaagttg atatactagt aaagtaatcg
    91441 atgcggggat ggcggaattg gcagacgcgc aggactaagg atcctgtgac cgctttaggt
    91501 cgtgagggtt caagtccctc tctccgcata ggaaaagagt tagctaaagc tagctctttt
    91561 gtatttctct aaaaaattag aatccagtca aatgtagtgg agaatcagcg aaaatatggg
    91621 aaaactgatc cttgtttctg cttttgtcat agaagaataa taaagattat cttcttcaaa
    91681 ttctccgata ttctctaaag ttttgtgcaa gttgcacaga acttttttat ttttttggtc
    91741 atcttgccat agaaatataa agcgttttca tatataatat aattatcaaa agacaaaagg
    91801 agttcacctc atggtagaat tgaatcttaa aaatatttac aaaaaatatc caaacagcga
    91861 acactattca gttgaagatt tcaacttgaa cataaaagat aaagaattta tcgttttcgt
    91921 aggaccttca ggatgtggta aatcaactac actccgtatg attgctggtc ttgaagacat
    91981 tacagaaggt actgcatcta tcgatggcgt ggttgtcaac gacgtagctc caaaagaccg
    92041 tgatatcgcc atggtattcc aaaactacgc tctttaccca cacatgactg tttatgacaa
    92101 catggctttc ggcttgaaat tgcgtaaata cagcaaagaa gacattaaca aacgtgttca
    92161 agaagcagct gaaatacttg gattgaaaga attcttggaa cgtaaaccag ctgacctttc
    92221 aggtggtcaa cgtcaacgtg ttgccatggg gcgtgcgatt gtccgtgatg cgaaagtatt
    92281 cttgatggac gaacctttgt caaacttgga tgccaaactt cgtgtatcaa tgcgtgctga
    92341 aatcgctaaa attcaccgtc gtatcggagc tacaactatc tatgtaactc acgaccaaac
    92401 agaagcgatg acacttgcag accgtatcgt tattatgtca gctactaaga accctgctgg
    92461 tacaggtact atcggacgtg tagaacaaat cggtactcct caagaagttt acaaaaatcc
    92521 agttaacaaa ttcgttgcag gattcatcgg aagcccagct atgaacttca tcaccgtgaa
    92581 attggttggt agcgaaattg tttctgacgg tttccgtttg aaagtgccag aaggagcatt
    92641 gaaagttctt cgtgaaaaag gctacgaagg aaaagaattg atctttggta tccgtccaga
    92701 agacgtgaat gcagaacctg ctttccttga aacattccca gactgtgttg taaaagcgac
    92761 tatctctgta tcagaactgc ttggttcaga atctcacctt tactgccaag ttggtaaaga
    92821 cgagtttgtt gcaaaagttg atgctcgtga ctacttgcaa acaggtgcaa cagttgagct
    92881 tggatttgac ttgaacaaag cacacttctt cgatgtagaa actgaaaaaa caatctacta
    92941 aaataaataa aattcaaagc actacaagaa aagatatctc tttatcaatt gtagtggaga
    93001 gatatcagtt aatctaggga gagaaacaaa atgcttctct cctttttgct agggaagtca
    93061 tattatgcat ctatattgtg atgctcttta tactcttcga aaatctcttc aaaccacgtc
    93121 aacgtcgcct tgccgtacgt atgattactg atttcgtcag ttttatctgc aacctcaaag
    93181 atgtactttg agcagcttac ggctagtttc ctagtttgct ctttgatttc cattgagtat
    93241 tattgtgagt accatctaca agtgaagcta tatgcgtaaa ctacgtgagc aattgaattc
    93301 gaactagaga ggtaataata aatttatgct atagttatgg tgacttgtat gcttttgatt
    93361 ctagtttatc aaataataga ttagaattgt cagataatat cattttgtgt tataatgaag
    93421 aaaaaacaga ggtgttcaaa tgtcagaagc aggtcataag tttttagcaa aattggggaa
    93481 aaaacgctta cgtccaggtg gaaagcgtgc cacagattgg ttaattgcag aaggaggatt
    93541 ttcaaaagaa aagagaatac tagaggttgc gtgtaatagg ggaactacag caattgagtt
    93601 ggcacagcgt tttggttgca agataactgc tgttgatatg gatgctcaag ctttagaagt
    93661 ggctaaaaaa tctgctggaa cggcaggtgt tgctcattta atcagttttg aaagagcaaa
    93721 tgcaatgaaa cttccttatc aagatgctag ttttgatatt gttataaatg aagctatgct
    93781 gactatgcaa gccgatcaag ctaagaaaaa atgtgtaatg gaatatctaa gggtattaaa
    93841 acctggaggt cttctcttga cacatgatgt gcttcttaag gaagctaaag agtctatcag
    93901 acaggaatta tcacaagcaa ttcatgtaaa tgtaggtcct ttaactcaag atggttggga
    93961 acaggtgatg atagaatcag gttattgtga tgtgaaagca ttgactggtg aaatgacatt
    94021 aatgaaatta tcgggtatga tttatgacga aggtttgcta ggaactttga aaatttgtgt
    94081 aaatgcttgt aaaaaggaga atagaaagca gtttttaact atgtataaaa tgtttgctaa
    94141 gaataaacag aaattgggct ttattgcgat ggctagttat aaatcgtcaa aacgttagat
    94201 aattattgaa gttaactttt ccttttttct ttcttaaaaa atatgctata atagagagta
    94261 aaaaactttg aaagaaagaa aaaagatgaa tttaaaagat tacattgcaa caattgaaaa
    94321 ttatccaaag gaaggcatta ccttccgtga tattagtcct ttgatggctg atggaaatgc
    94381 ttatagctac gctgttcgtg aaatcgttca gtatgctact gacaagaaag tcgacatgat
    94441 cgtgggacct gaagctcgtg gatttatcgt gggttgtcca gttgcctttg agttgggaat
    94501 tggttttgcg cctgttcgta agccaggtaa attgccacgt gaagttattt ctgctgacta
    94561 tgaaaaagag tacggtgtcg ataccttgac tatgcacgcg gatgccatta agccaggtca
    94621 acgtgttctt attgtagatg accttttggc gacaggtgga actgttaagg caactatcga
    94681 gatgattgaa aaacttggtg gtgttatggc aggttgtgcc ttccttgttg aattggatga
    94741 attgaacggc cgtgaaaaaa ttggtgacta cgactacaaa gttcttatgc attattaatg
    94801 aaaacagtcc ctagggctgt tttctctaca ctaggatata aaaatagact ataactagtt
    94861 agagaaaaac tataattgaa aactatatct tcttgcagta taataaaagg actaagtgtt
    94921 tgagatttgt cttcaaacat atgcaattat tcctgaaaga gtacagttag gagagggtta
    94981 tgccgattcg aattgataaa aaattgccag ctgttgagat tttacggaca gagaatatct
    95041 ttgtcatgga tgatcaacgt gctgcccacc aagatatccg tcctttgaag attttaattt
    95101 taaatctcat gccacagaaa atggtcacag agacccagtt gttgcgccac ttggctaata
    95161 cacccctaca actggatatt gattttctct atatggagag ccaccgttct aaaacaactc
    95221 gttcagagca catggagacc ttctataaaa cttttcctga agtcaaggat gagtattttg
    95281 atgggatgat catcacgggt gctccagttg agcatttacc atttgaggaa gtggactatt
    95341 gggaggaatt tagacagatg cttgagtggt ctaagactca tgtctattcg acccttcata
    95401 tctgttgggg ggctcaggct gggctttatc tgcgctatgg tgtagaaaaa taccagatgg
    95461 acagtaagct atcaggtatt tatcctcagg acaccctaaa agagggtcac cttctattta
    95521 gaggctttga tgatagctat gtatcccctc attcacggca cacggagatt tctaaggaag
    95581 aggtcttaaa caagaccaat ctcgagattt tatcagaagg acctcaggtt ggggtttcta
    95641 ttttggccag tcgtgattta cgagaaattt atagttttgg tcatttggag tatgaccgtg
    95701 ataccttggc aaaagagtat tttcgagatc gtgatgcagg tttcgaccca catattccag
    95761 aaaattactt taaagatgat gatgttaatc aggtaccttg tctttgttgg tcttcatctg
    95821 cagccctctt tttcagtaat tgggtaaacc atgcggtcta tcaggagacg ccttttgatt
    95881 ggagaaagat agaagatgat gcatctgcat atgggtattt ataagaggaa ttatgacata
    95941 tttagacgct tttaaatcag gtaccttggt tttaccgagt gccctgctct tgcattttaa
    96001 ggaactcttt ccttctagcg acgattttct ggtttggcaa tttttctatt tgcaaaatac
    96061 gacaggctta gaagaaatgt cgccaagcca gattgctgaa aggattggca aggaaatttc
    96121 ggatgtcaac cagtccattt ctaatctgac ggaaagggga ctgctccagt atcgtactat
    96181 cgaattaaat ggcgaaattg aattgctctt tgatgctagt ttggccttgg aacgtttgga
    96241 tgacctgttt ggagcagttc attcaagttc agaccagcta acacctcaaa accagctcaa
    96301 ggatttggtg gaaaccttcc agcaggagtt gggacgattg ttgacgcctt ttgagattga
    96361 ggatttgacc aagacactaa aggaagatgg aaccagtgct gacttgatta aggaggctct
    96421 tcgtgaagct gttttgaatg gaaaaccaaa ctggaagtac attcaggcta ttttgagaaa
    96481 ctggcgccat gaaggaatca agagtgtggc tcaaattgag gccaagagag cagaaagaga
    96541 agcaagcaat cctcagttga cacaggtatc tgcagatttc agaaatgcca tggatctctg
    96601 gaaggattaa tccatgcaag taggcttgaa atccgagtaa gatttgcaag ctgtgtataa
    96661 ttgtgataga ataaatagaa aataaattga aaaaagaggt atgtgaaatg tcacgtaaac
    96721 catttatcgc tggtaactgg aaaatgaaca aaaatccaga agaagctaaa gcattcgttg
    96781 aagcagttgc atcaaaactt ccttcatcag atcttgttga agcaggtatc gctgctccag
    96841 ctcttgattt gacaactgtt cttgctgttg caaaaggctc aaaccttaaa gttgctgctc
    96901 aaaactgcta ctttgaaaat gcaggtgctt tcactggtga aactagccca caagttttga
    96961 aagaaatcgg tactgactac gttgttatcg gtcactcaga acgccgtgac tacttccatg
    97021 aaactgacga agatatcaac aaaaaagcaa aagcaatctt tgcgaacggt atgcttccaa
    97081 tcatctgttg tggtgaatca cttgaaactt acgaagctgg taaagctgct gaattcgtag
    97141 gtgctcaagt atctgctgca ttggctggat tgactgctga acaagttgct gcctcagtta
    97201 tcgcttatga gccaatctgg gctatcggta ctggtaaatc agcttcacaa gacgatgcac
    97261 aaaaaatgtg taaagttgtt cgtgacgttg tagctgctga ctttggtcaa gaagtcgcag
    97321 acaaagttcg tgttcaatac ggtggttctg ttaaacctga aaatgttgct tcatacatgg
    97381 cttgcccaga cgttgacggt gcccttgtag gtggtgcgtc acttgaagct gaaagcttct
    97441 tggctttgct tgactttgta aaataatcag taagtagcaa aagctaggtg gaacagcatt
    97501 cagatgtctg ttacattttt tataggagag caaagattga aaacaaaaat tggattagca
    97561 agtatctgtt tactaggctt ggcaactagt catgtcgctg caaatgaaac tgaagtagca
    97621 aaaacttcgc aggatacaac gacagcttca agtagttcag agcaaaatca gtcttctaat
    97681 aaaacgcaaa cgagcgcaga agtacagact aatgctgctg cccactggga tggggattat
    97741 tatgtaaagg atgatggttc taaagctcaa agtgaatgga tttttgacaa ctactataag
    97801 gcttggtttt atattaattc agatggtcgt tactcgcaga atgaatggca tggaaattac
    97861 tacctgaaat caggtggata tatggcccaa aacgagtgga tctatgacag taattacaag
    97921 agttggtttt atctcaagtc agatggggct tatgctcatc aagaatggca attgattgga
    97981 aataagtggt actacttcaa gaagtggggt tacatggcta aaagccaatg gcaaggaagt
    98041 tatttcttga atggtcaagg agctatgatg caaaatgaat ggctctatga tccagcctat
    98101 tctgcttatt tttatctaaa atccgatgga acttatgcta accaagagtg gcaaaaagtg
    98161 ggcggcaaat ggtactattt caagaagtgg ggctatatgg ctcggaatga gtggcaaggc
    98221 aactactatt tgactggaag tggtgctatg gcgactgacg aagtgattat ggatggtgct
    98281 cgctatatct ttgcggcctc tggtgagctc aaagaaaaga aagatttgaa tgtcggctgg
    98341 gttcacagaa acggtaaacg ctatttcttt aataatagag aagaacaagt gggaaccgaa
    98401 catgctaaga aaatcattga tattagtgag cacaatggtc gtatcaatga ttggaaaaag
    98461 gttattgatg agaacgaggt ggatggtgtc attgttcgtc taggttatag cggtaaagaa
    98521 gacaaggaat tggcgcataa cattaaggag ttaaaccgtc tgggaattcc ttatggtgtc
    98581 tatctctata cctatgctga aaatgagacc gatgctgaga atgacgctaa acagaccatt
    98641 gaacttataa agaaatacaa tatgaacctg tcttacccta tctattatga tgttgagaac
    98701 tgggaatatg taaataagag caagagagct ccaagtgata cagacacttg ggttaaaatc
    98761 atcaacaagt acatggacac gatgaagcag gcgggttatc aaaatgtgta tgtctatagc
    98821 tatcgtagtt tattacagac gcgtttaaaa cacccagata ttttaaaaca tgtaaactgg
    98881 gtagcggcct atacgaatgc tttagaatgg gaaaaccctt attattcagg agaaaaaggt
    98941 tggcaatata cctcttctga atacatgaaa ggaatccaag ggcgcgtaga tgtcagcgtt
    99001 tggtattaag cgatgatttg aaagagggat gtgatagtag caccctcttt ttctttgttt
    99061 tatgatagtt catcctcgag taaattcaag atcttgctcg gaaatgaagc ttatatagta
    99121 gattgaatat agacaaatac cttgtgattg gtaaaacatt ttagaaattc atttaccttt
    99181 cctaatcgac ttggtttcat cttatttcaa tctattatag tattggggaa tttcttcaaa
    99241 ccacatcagc ttggtcagtt ctacctgcga cctcaaaact tgtgctttgg tcaagctggg
    99301 tttagtttcc tagtttgctg atggatttcc attgactata agcatccaac cctctttttg
    99361 tcttctaaag aattcttaaa ttatcagtct attgcaactt ttctcatata agttctttgt
    99421 cttgctattt gttttcctta gtagtatact aaggtagtaa tcattaagaa gtggttacaa
    99481 aaaataatga atgaggtaaa gaaaatggta gaattgaaaa aagaagcagt aaaagacgta
    99541 acatcattga caaaagcagc gccagtagca ttggcaaaaa caaaggaagt cttgaaccaa
    99601 gctgttgctg atttgtatgt agctcacgtt gctttgcacc aagtgcactg gtatatgcat
    99661 ggtcgtggtt tccttgtatg gcatccaaaa atggatgagt acatggaagc tcttgacggt
    99721 caattggatg aaatcagcga acgcttgatt acactcggtg gaagcccatt ctctacattg
    99781 acagagttcc ttcaaaatag tgaaatcgaa gaagaagctg gtgaataccg taatgttgaa
    99841 gaaagcttgg aacgtgttct tgttatctac cgttacttgt cagaactttt ccaaaaaggt
    99901 ttggatgtca ctgatgaaga aggtgacgat gtgacaaacg gtatctttgc aggcgctaaa
    99961 actgaaacag ataaaacaat ttggatgctt gcagccgaac ttggacaagc acctggtttg
   100021 taagaaataa ggaaacatag ataaatctgt aggaaatttc ttacagattt tttctatttt
   100081 gtaagctatt ccaaaccagt ctttttttga gttttttgat aaaatagtac tatcagtgaa
   100141 aaggatggaa gcatgactaa gaaaatcgta gctatttggg cccaggatga agagggtgtg
   100201 attggtaagg aaaatcgtct gccttggcat ttgccagcag aattgcagca ctttaaagaa
   100261 acaactctga atcatgctat cttgatgggg cgtgtgacct ttgatgggat ggggcgtcgc
   100321 ttgcttccaa aacgggaaac cctgattttg acgcgtaatc cggaagaaaa gatagatggg
   100381 gttgctactt ttcaggacgt ccagtctgtt cttgactggt atcaggatca agaaaagaat
   100441 ctctacatta tcggtgggaa gcaaattttt caggcttttg aaccttacct tgatgaagtg
   100501 attgtcactc acattcatgc tcgggtggaa ggagatacct atttccctga agagcttgac
   100561 ttgtctcttt ttgagacagt ttcaagcaaa ttttacgcca aagatgagaa gaatccttat
   100621 gattttacca tccaataccg caagagaaag gaagtataat ggaacggagt ttatttggtc
   100681 tattcacggc ttttctgtgt ttcatctgct ttctggcagg agcacaggct tttcgtaaaa
   100741 agcgttacgg gctttctatc ctcctttggt taaatgcctt taccaatctg gtcaatagta
   100801 ttcatgcttt ttacatgacc ttattttaga tagaatgaca gtatagaatg gaaggaaatc
   100861 atgtctacaa atagaaaaaa tgatatgatg gtttattgct cattttgtgg caaaaaccaa
   100921 gaagaagtac aaaaaataat tgctggcaac aatgctttta tttgtaatga atgcgtggag
   100981 ttagctcagg aaatcattcg agaagaattg gttgaggaag tcttggcaga cttgtctgag
   101041 gtgccaaaac caattgaact cctccatatc ttgaaccact atgtaattgg tcaagatcgt
   101101 gccaagcgtg ccttggcagt ggcggtttat aaccactaca aacgcatcaa tttccacgat
   101161 acacgcgaag agtcagaaga tgtggatttg cagaagtcaa acattttgat gattggccca
   101221 actggttcag ggaaaacttt ccttgcccag accttggcta agagcttgaa tgtgcctttt
   101281 gctattgcgg atgcgacagc tctgacggag gctggttatg tgggtgagga cgtggaaaat
   101341 atcctcctca aactcttgca ggttgctgac tttaacatcg aacgtgcaga gcgtggcatt
   101401 atctatgtgg atgaaattga caagattgcc aagaagagtg agaatgtgtc tatcacacgt
   101461 gatgtttctg gtgaaggggt gcaacaagcc cttctcaaga ttatcgaggg aactgttgct
   101521 agcgtgccgc ctcaaggtgg acgcaaacat ccacaacaag agatgattca agtggataca
   101581 aaaaatatcc tcttcatcgt gggtggtgct tttgatggta ttgaagaaat tgtcaaacaa
   101641 cgtctgggtg aaaaagtcat cggatttggt caaaataata aggcgattga cgaaaacagc
   101701 tcatatatgc aagaaatcat cgctgaagac attcaaaaat ttggtattat ccctgagttg
   101761 attggacgct tgcctgtttt tgcggctctt gagcaattga ccgttgatga cttggttcgc
   101821 atcttgaaag agccaagaaa tgccttggtg aaacaatacc aaactttgct ttcttatgat
   101881 gatgttgagt tggaatttga cgacgaagcc cttcaagaga ttgctaataa agcaatcgaa
   101941 cggaagacag gggcgcgtgg acttcgctcc attatcgaag aaaccatgct agatgttatg
   102001 tttgaggtgc cgagtcagga aaatgtgaaa ttggttcgca tcactaaaga aactgtcgat
   102061 ggaacggata aaccgatcct agaaacagcc tagaggtgac tatggaactt aatacacaca
   102121 atgctgaaat cttgctcagt gcagctaata agtcccacta tccgcaggat gaactgccag
   102181 agattgccct agcagggcgt tcaaatgttg gtaaatccag ctttatcaac actatgttga
   102241 accgtaagaa tctcgcccgt acatcaggaa aacctggtaa aacccagctc ctgaactttt
   102301 ttaacattga tgacaagatg cgctttgtgg atgtgcctgg ttatggctat gctcgtgttt
   102361 ctaaaaagga acgtgaaaag tgggggtgca tgattgagga gtacttaacg actcgggaaa
   102421 atctccgtgc ggttgtcagt ctagttgacc ttcgtcatga cccgtcagca gatgatgtgc
   102481 agatgtacga atttctcaag tattatgaga ttccagtcat cattgtggcg accaaggcgg
   102541 acaagattcc tcgtggtaaa tggaacaagc atgaatcagc aatcaaaaag aaattaaact
   102601 ttgacccgag tgacgatttc atcctctttt catctgtcag caaggcaggg atggatgagg
   102661 cttgggatgc aatcttagaa aaattgtgag gaaaagaaaa tggcaaaaac aattcataca
   102721 gataaggccc caaaggctat cggaccctat gttcaaggaa aaatcgttgg caaccttttg
   102781 tttgctagcg gtcaagttcc cctatcccct gaaactgggg aaattgtagg agagaatatc
   102841 caagaacaga cagagcaagt cttgaaaaac atcggtgcta ttttggcaga agcaggaaca
   102901 gactttgacc atgttgtcaa aacaacttgt ttcttgagcg atatgaacga ctttgttcct
   102961 tttaatgagg tttaccaaac ggccttcaaa gaggaattcc cagctcgttc agctgtggag
   103021 gtagctcgtc ttcctcgtga tgtaaaagtc gaaattgaag tcatcgcaga gattggataa
   103081 gctagttgaa gtttggtgtt gccaaacttc ttttgatata aggagaaaaa gatgacaaag
   103141 aaacaacttc acttggtgat tgtgacaggg atgagtggcg cagggaaaac tgtagccatt
   103201 cagtccttcg aggatctagg ttatttcacc attgataata tgccgccagc tctcttgcct
   103261 aagtttttgc agctggttga aattaaggaa gacaatccta agttggcctt ggtagtggat
   103321 atgcgtagcc gttctttctt ttcagagatt caagctgttt tggatgagtt ggaaaatcaa
   103381 gatggtttgg atttcaaaat cctctttttg gatgcggctg ataaggaatt ggtcgctcgt
   103441 tacaaggaaa ccagacggag tcacccacta gcagcagacg gtcgtatttt agatggaatc
   103501 aagttggaac gtgaactctt ggcacctttg aaaaatatga gccaaaatgt ggtggatacg
   103561 actgaactca ctccacgtga gctgcgcaaa acccttgcag agcagttttc agaccaagaa
   103621 caagcccagt ctttccgtat cgaagtcatg tctttcggat ttaagtatgg aatcccgatt
   103681 gatgcggact tggtctttga tgtccgtttc ttgccaaatc cctattattt accagaactg
   103741 agaaaccaaa cgggtgtgga tgaacctgtt tatgattatg tcatgaacca tcctgagtca
   103801 gaagactttt atcaacattt attggccttg attgagccga ttctgccaag ttaccaaaag
   103861 gaaggtaagt ccgttttgac cattgccatg ggatgtacgg gtggacaaca ccgtagtgtg
   103921 gcatttgcta aacgcttggt gcaggactta tccaagaatt ggtctgttaa tgaagggcat
   103981 cgcgacaaag accgcagaaa ggaaacggta aaccgttcat gagaaaacca aagataacgg
   104041 tgattggtgg agggactgga attcccgtca ttctaaaaag tctgcgggaa aaagatgtgg
   104101 aaatcgcagc tatcgtgacg gtggcagatg atggtggttc ttcaggtgaa ctccgaaaaa
   104161 atatgcaaca gttgacaccg ccaggtgatt ttcgtaatgt ccttgtggcc atgtcggata
   104221 tgcctaagtt ttatgagaag gtctttcagt atcggttctc tgaggatgcc ggagcctttg
   104281 ctggccatcc attgggaaat ctcatcattg ctggcttgtc agaaatgcag ggttcaacct
   104341 ataatgccat gcagttattg agcaaatttt tccatacaac agggaaaatt tatccttcca
   104401 gtgaccatcc tttgaccctt catgcagtct ttcaggatgg gacagaagtg gctggagaga
   104461 gtcatattgt agaccatcga ggcataattg acaatgtcta tgtgaccaat gccctaaacg
   104521 atgatacgcc tctggccagc cgtcgagtag tgcagaccat ccttgaaagt gacatgattg
   104581 tcctagggcc aggttctctc tttacctcta ttttgcccaa tatcgtgatt aaggaaattg
   104641 ggcgggctct tttggaaacc aaggcagaaa ttgcctatgt ctgcaatatc atgacccaac
   104701 gtggggagac ggaacacttt acagatagcg accacgtgga agtcttgcat cgtcaccttg
   104761 gtcgcccttt tatcgacact gtcttggtga atattgaaaa agtgcctcag gaatacatga
   104821 attccaaccg ttttgatgaa tacttggtgc aagtggaaca cgattttgta ggtctttgta
   104881 agcaagtttc gcgcgtgatt tcatctaact tccttcgtct ggaaaatggc ggtgccttcc
   104941 acgatggaga tttgattgtg gacgagttga tgcgcattat acaggtgaaa aaatgagttt
   105001 cacagtagca gtaaaagaag aaatcctggg ccaacaccat ctgagctggc atgaattatc
   105061 tgccattatc aaaatgtctg gtagcatcgg tctctcgact tcgggcttga ctttgtcagt
   105121 tgtgacagaa aatgccaaac tggcccgtca cctctatgag tcctttctcc atttctatga
   105181 aatcaaatct gaaattcgtc accaccaacg gagcaatctt cgcaagaatc gcgtctatac
   105241 cgtttttaca gatgaaaagg tgcaggattt gttaagtgat ttgcacttgg cagactcttt
   105301 ctttggcctg gaaacaggta ttgatgaggc gattttatcg gatgaggaag caggtcgtgc
   105361 ctatctctgt ggcgctttct tggcaaatgg gagcattcgt gaccctgagt caggcaagta
   105421 ccagttggaa atcagttctg tttatctgga ccacgcgcaa ggaattgcct cccttctcca
   105481 acagttttta ctggatgcca aggtgcttga gcgcaagaag ggggctgtga cctatctcca
   105541 gcgagcagaa gacattatgg acttcttgat agtaatcgga gccatgcagg cacgtgatga
   105601 ttttgagcgg gttaagattt tgcgagaaac ccgtaacgac ctcaatcggg ctaataatgc
   105661 cgagacagct aatatcgctc ggacagtttc tgccagcatg aagaccatta acaatatcag
   105721 taaaataaaa gatatcatgg gcttagaaaa tttgccagta gatttgcagg aagtggcgca
   105781 actgaggatt cagcacccag actactctat ccaacagttg gcagatagcc tcagcacccc
   105841 tctgaccaaa agtggtgtca atcacagact cagaaaaatc aataagatag ccgatgaatt
   105901 ataaaaccac gaatcctatg tgactcgtgg ttctttttta taaactagta gagtgttttg
   105961 gttgtacttt ttgttcaggg tcaatgtagt tgatagcgtt gttgacagca gttggagctt
   106021 ctccgaggcc tgtcgcaatc agatcaattt ttccgtcata gtagcagcag tcaccgatag
   106081 catagatacc tgcttggctg gattcctgtt tgctgttgac gataatcttg tgacggttga
   106141 ggtcgagccc ccagttttta aggttaccga cagaagattt gaaaccatag ttgacaaaga
   106201 ggtggtctag gtcaatggtt tcagtttcat cagatttgac ttttgtgatt tcaagtttat
   106261 caagtgtttt tccatttcca aggagttggc taggggcgaa tggtgtcttg atggttacag
   106321 atgattcttg caaggcttga acactgtgtt ccaaggcacg gaaattatct ctgcggtgaa
   106381 caagggtagt tggtgcgatt ttttcaaaag ccaaagccca atccacagcc gagtctcccc
   106441 caccaagaat cgtcactttc ttaccagcgt attgctgaat gttagaaacg tggtagtgga
   106501 tattttcata gccctcaaca ctttcaagtt ccagcggacg tggtttgaag gcaccgccac
   106561 ccatagcgat gataactgtt ttagtcaggt gacttccttt agaagttgtg atggcaaatt
   106621 cttcttcttg tttgtcaatc tcaagaaccg tttcattgag atgaataggg gtatcaaatc
   106681 catttagctg ttcaatcaag cggttagtca actcttctcc agtcaggttt gggaagcctg
   106741 gtacgtctag gatttccttt tcagggtaga gaatagcagg ttgtccacct agctggggaa
   106801 gagagtcgat gatttgaacc ttggcttggc gtaggtgggc ataaaaggct gcaaaaagcc
   106861 cgacaggacc accacccaca atggtaatat catagagttg agacatagtt tctcctttgt
   106921 tttttctagt cagtttattt tatcatattt ttgttcaatg taaaatggac taggataggg
   106981 aaaaaaatgc cagaaaatgg tataatagga cgaaagtgtt ttgataggga ggatatcagg
   107041 gatgaatttt caacaattat ccaatctgca atattggacc agtttgtttg caagtccatg
   107101 gacgatagct atcaatctga ttgatatttt gattgttgct tatattttat accattttac
   107161 aaaagctatt gcaggaacca agattatgat tttggtacgt ggagttttgg tgtttatttt
   107221 agctcaaatc cttgcaaata tgattggttt gactacgatt tcttggttaa tcaatcaaat
   107281 tattacttat ggggttattg cggcggttgt tatcttctct ccagagattc ggactggttt
   107341 ggaacgtttg ggaagagcga cagatttctt ttccaatgcc cctattagtg ctgaggaaca
   107401 gatgattcgt gcctttgtta agtctgttga atacatgagt cctcgtaaaa tcggggcctt
   107461 ggttgctatt cagcgtgtac gtaccttgca ggagtatatg tcgacaggaa ttcccttgga
   107521 tgctaagatt tctgcagaac ttctcattaa catttttatt cccaacactc ccctacatga
   107581 cggtgcggtg attatcaaag aagaacgtat cgctgtgacg tctgcctatc tgcccttgac
   107641 aaaaaacaca gggatttcca aggaatttgg gaccagacac cgggcggcta tcggtttatc
   107701 agaagtctca gatgccttga cttttgtcgt atcagaggaa acgggaggaa tttcgataac
   107761 ctataatgga aggtttaagc acaacctaac acttgatgaa tttgaaacag aattacgtga
   107821 aatcttactt ccaaaagagg aagtgggtct tagttttaaa gaacgattgc taggaggatg
   107881 gaaacatgaa aaaaaatagt ttatatatca tatcctcact cttttttgct tgtgtcttat
   107941 ttgtctatgc tacggcgacg aattttcaaa acagtaccag tgctaggcag gtaaaaacgg
   108001 aaacctatac taatacagta acaaatgtcc ctattgacat acgctataat agtgataagt
   108061 attttattag cggttttgct tcagaagtat cagtggtctt gactggtgca aatcgcctat
   108121 cgctagctag tgaaatgcaa gaaagtacac gtaaattcaa ggttactgct gacctaacag
   108181 atgccggtgt tggaacgatt gaagttcctt tgagcattga agatttaccc aatgggctga
   108241 ccgctgtggc gactccgcaa aaaattacag tcaagattgg taagaaggct caaaaggata
   108301 aggtaaagat tgtaccagag attgacccta gtcaaattga tagtcgggta caaattgaaa
   108361 atgtcatggt gtcagataaa gaagtgtcga ttacgagtga ccaagagaca ttggatagaa
   108421 ttgataagat tatcgctgtt ttgccaacta gcgaacgtat aacaggtaat tacagtggtt
   108481 cagtaccttt gcaggcaatc gaccgcaatg gtgttgtctt accggcagtt atcactccgt
   108541 ttgatacaat aatgaaggtg actacaaaac cagtagcacc aagttcaagc acatcaaatt
   108601 caagtacaag cagttcatcg gagacatctt cgtcaacgaa agcaactagt tcaaaaacga
   108661 attaaaaata gaaaaggatt ttataacaat gggtaaatat tttgggactg atggagtccg
   108721 tggagaagct aacctagaac taacaccaga attagccttt aaactaggac gttttggagg
   108781 ctatgttctt agtcaacatg aaacggaagc gccgaaagtc tttgtaggac gtgacacacg
   108841 tatttcaggg gaaatgctgg aatcggcctt ggtggcaggt ctcctttcag tagggattca
   108901 cgtatacaaa cttggtgtcc ttgcaacacc agcagtagct tacttggttg aaactgaagg
   108961 agcaagtgcc ggtgtcatga tttctgctag ccacaaccca gcccttgata acggaatcaa
   109021 gttctttggc ggtgatggct tcaaactaga tgatgaaaaa gaagcagaaa ttgaagcctt
   109081 gctagatgct gaggaagaca ctcttcctcg tccaagtgca gaaggcttag gaattttggt
   109141 agattatcca gaaggcttgc gtaagtatga aggatacctt gtttcaactg gaactcctct
   109201 tgatggaatg aaggttgcct tggatacagc taatggagca gcttctacca gtgcccgtca
   109261 aatctttgca gaccttggtg cccaattgac ggttatcggg gaaacaccag acggtcttaa
   109321 catcaacctt aatgttggtt caacacatcc agaagccctt caagaagtgg tcaaagaaag
   109381 tgggtcagct attggtttgg cctttgatgg agacagtgac cgcttgattg ctgttgatga
   109441 gaatggtaac atcgtcgatg gtgacaagat tatgtacatc atcggaaaat acctttctga
   109501 aaaaggacaa ttggctcaaa atacaattgt gacaactgtt atgtctaacc ttggtttcca
   109561 caaggccttg aatcgcgaag gtattaacaa ggcagttact gcagttggtg accgctacgt
   109621 tgttgaagaa atgagaaaat caggctacaa ccttggtggt gaacagtctg gtcacgttat
   109681 cttgatggat tacaatacca caggtgatgg tcaattatca gcagttcaat tgactaaaat
   109741 catgaaggaa actggtaaga gcttatcaga gttggcggca gaagtaacga tttatccaca
   109801 aaaattagtt aatatccgag tggaaaacgt catgaaggaa aaggccatgg aagtgccagc
   109861 tatcaaggcc atcatcgaga agatggaaga agaaatggcg gggaacggcc gtatccttgt
   109921 tcgtccaagt ggaacagaac ccctcttgcg tgttatggca gaagcgccta caacagaaga
   109981 agtagactac tatgttgata ccatcacaga tgtagttcgt gctgaaattg ggattgacta
   110041 aatcctagaa aactagatga aaataaaaaa ttatggtaca atagcttata atattgtagc
   110101 cgatggagaa agacatgaat cttaaacgtg aacaagaatt tgttagtcag tatcattttg
   110161 atgcgcgtaa ttttgaatgg gaaaatgaaa atggagctcc tgaaaccaag gtggatgtga
   110221 atttccaatt gctccaacat gaccaagaaa atcaagtgac ttccttgatt gtcatcttga
   110281 gctttatgat tgtatttgat aagtttgtca ttagtggaac aatctcacaa gtaaaccata
   110341 tcgatggccg tattgtcaat gaaccaagtg aattgaacca agaagaggtg gaaaccttgg
   110401 ctcgtccatg tttgaacatg ctcaatcgtt tgacttacga agtgactgaa attgcattag
   110461 acttaccagg aattaatttg gagttctaat atgaaattag ctgttttcac agattcctct
   110521 gcttatctca gtgaagagac cttgcaaaga gaagacttgt ttgtcttgga tattcctgtc
   110581 aatattgatg gtgaggaata tgtcgaaggc atcaatctgt ctgctgagga attttaccaa
   110641 aaaatggctc aggcttctga attgcctaag accagtcaac caagtattgc caagttagat
   110701 gagatcttaa cttcgctcaa agaacaaggc tatacacatg ccttggggct tttcctatct
   110761 tctggaattt caggttttta ccaaaatatc cagtatatgg tcgatgacta tgagggctta
   110821 accattgctt tcccagacac tttgattaca agtgctcccc taggcatcat ggttgaaagc
   110881 gtctttaatt ggcgtgatca gggcgatgat tttgccagca ttcaggataa gctagccatt
   110941 caaatcagcc gtacgtcagc ctttatcatg gtagatgact tggatcattt ggtaaaaggt
   111001 ggacgccttt caaatggggc tgccattttg ggcaatttgc ttagcattaa gccaatcctt
   111061 tattttaacg atcaaggtgt gattgaagtt tacgaaaaag ttcgtactga aaagaaggcc
   111121 accaagcgct taattgaaat tatcaaggaa acaacggctt caggtcaata ccgggtcatt
   111181 gtcattcatg ggaatgctcc tgaaaaggct gaagaattgc gtcagcactt gcttgatttt
   111241 ggcttgggtt cggatgtttc acttgctaca tttggtagtg tcattggaac gcacctagga
   111301 gcaggaagta ttgctctggg ttatattcca gtgatttagt tggcgcttct aggctagtta
   111361 agatgccttg tatcttagaa attgaacacg gactacctgc ctcttgaaaa aagatgcctg
   111421 tcttgccttt cgtggaaagt cagtgccatt ccctattttt cagaggcagc taaggtcctt
   111481 tgtatcttga taattgaaca cgcctggaac cctgtgtgaa aaagatagtt cttccaagaa
   111541 gtagacactt cttgattgga attcctattt tcactttgtg ttcttacgga ctttgtatct
   111601 tagacaggag tagagatgag tattcgagta attattgccg gttttaaggg aaagatgggc
   111661 caggctgctt gtcagatggt attgactgat ccagacttgg acttggtagc agttttggat
   111721 ccttttgagt ctgagtcaga atggcagggt attcctgttt tcaaggataa ggctgattta
   111781 gctggttttg aagcggatgt ctgggtagat tttactactc cagctgttgc ctacgaaaat
   111841 acacgttttg ctcttgaaaa tggctttgct ccagtagttg gaacgactgg tttcacgagt
   111901 gaagaaattg cagagctaaa agaattttct cgtgcccaag acttgggtgg cctgattgcc
   111961 cctaactttg ccttgggtgc tgtcttactc atgcaatttg cgacgcaggc tgccaaatat
   112021 ttcccaaatg tggagattat tgagctccat catgacaaga aaaaggatgc tccgagtgga
   112081 acagccatta aaacagctga gttgatggca gaggttcgag agtccattca gcaaggcgca
   112141 gcagatgagg aagagctgat tgctggtgct cgtggtgctg actttgatgg tatgcacatc
   112201 cactcagttc gtttgccagg tttggtagcc catcaggaag tcatctttgg caatcaggga
   112261 gaagggttga ccctccgtca tgactcctat gatcgcatct ccttcatgac aggagtcaat
   112321 ttgggaatta aagaagttgt caagcgtcat gagcttgtct atggattaga acacttatta
   112381 tgagattaac gcaaatgcct tctgaatttc agaaggcttt accagtatta gaaaaaatta
   112441 aagaagcagg ctttgaggct tattttgttg ggggctctgt tcgagatgcc cttctccata
   112501 accctatcca cgatgtggat attgcgacgt cttcttatcc agaagagacc aagcagattt
   112561 ttccgcgaac agccgatatc ggaatcgagc atggaaccgt cttggtctta gatggggatg
   112621 aggagtatga ggtaacaacc tttcggacag aggatgtcta tgtggactat cgcagaccca
   112681 gtgcggtttc ctttgtgcgc tcgctagaag aagacctcaa acgccgtgat ttcacagtca
   112741 acgcctttgc cttggatgag acaggagaaa tcgttgactt gttccatggt ttagaagatt
   112801 tggaaaagca agtcttgcga gcagttggag tggctagtga gcgtttcaac gaagatgctt
   112861 tacggattat gcgtggtttc cgttttcagg ctagtcttgg ttttgcactt gaaccagaaa
   112921 catttaaagc tatgaagacc ttgacgccgc ttttggagaa catttctgta gagcgtacct
   112981 tcgtcgagtt tgataaactc ttgctggctc cattttggag aaggggcttg gcttccatga
   113041 ttgagagtca agcttatgac tatctccctg atatggcatc tagccaggac aagctcaaca
   113101 gactgtttga tttggagact gattttactt ttgaatcctc tgaacaagcc tgggcggctt
   113161 tactatgggc tttggagatt gaaaatgcgc agtcattttt gaaatcttgg aagacctcac
   113221 gccagtttgc caagcaagtt caggatttgc tgattatttt ggctctgcgt gaaaatggag
   113281 aattgagcaa gcgagattgt tatcgctttg acatagattt gcttttacag gctgaaaatc
   113341 ttcgtcaagc tcaaggaaaa gaagtcaacc cacaagccat cacagaaaaa taccaaagct
   113401 tgactatcca tgacaagaaa gagattcaga ttaatggcgg tattttgatc aaggaatatg
   113461 gctatcagcc aggcccagac ttgggagaga ttttaacaga gattgagttt gccattgtcg
   113521 atggagaatt ggagaataat cgtgaagcca tccatgctta cctgagggag aaaaaatgag
   113581 tgattttatc gttgaaaaac taagtaaatc cgttggtgac aagaccgttt ttagggatat
   113641 ttcctttatt atccatgact tagacagaat tggtttaatc ggtgtcaatg ggactggcaa
   113701 gaccaccctt ttggacgtcc tttctggtgt ttctggattt gatggggatg tcagtccttt
   113761 ttcagctaaa aatgattacc agattggtta cttgactcag gatcctgatt ttgatgatag
   113821 aaagacagtt ttggatacgg ttctatctag tgaactcaag gaaatccagc tcattcgtga
   113881 gtatgaattg attatgctcg actatagtga ggacaagcag gcgcgtttgg aacgtgtcat
   113941 ggcagagatg gactctctcc aagcttggga aatcgaaagt caggtcaaga ccgttcttag
   114001 caaattgggc attcaagact tatctactcc tgttggggaa ttgtcaggtg gtctgagaag
   114061 acgggtacag ttggcacaag tcttacttgg caaccacgac ctcttgcttt tggatgagcc
   114121 gaccaaccat ctggatattg cgattattga gtggctgacc ctctttttga aaaattctaa
   114181 gaagaccgtc ctttttatca ctcacgatcg ttatttctta gacgctttgt caacacggat
   114241 tttcgagttg gatcgtgcag gcttgaccga gtaccaggga aattaccagg actatgttcg
   114301 cctaaaggcg gaacaggatg agcgcgacgc ggctcttctt cacaaaaaag aacaactcta
   114361 caaacaagaa ttggcctgga tgcgcagaca accgcaggcg cgtgcgacca agcagcaggc
   114421 ccgtatcaat cgattccatg atctgaaaaa ggaagtttca ggcagtagtg ctgagacaga
   114481 cttgaccatg aactttgaaa ccagtcggat tgggaagaaa gtcatcgagt ttcaggctgt
   114541 ttcctttgcc tatgaaaaca agcctatttt gcaagatttt aatctcttgg tgcaggccaa
   114601 agaccgtatc ggaatcgttg gggacaatgg tgttggaaaa tcaaccctgc tcaacttgat
   114661 tgcaggaagt cttgagccaa ctaaaggaca agttgtgatt ggggaaactg ttcgcatcgc
   114721 ctatttctct cagcaaattg agggtttgga tgaaagcaag agagttatca attacctgca
   114781 ggaagtggca gaagaggtca agaccagtgg cggttctacg acttcgattg cagagttgct
   114841 ggagcagttc cttttcccac gttcgacgca tggaaccttg attgagaaat tgtcaggggg
   114901 tgagaaaaaa cgtctttatc tcctcaaact gcttttggaa aaaccaaatg ttcttctttt
   114961 agacgagcca accaatgacc tagatattgc aactttgaca gtcttagaga atttcttgca
   115021 aggttttgca ggtcccgttt taacagtcag tcacgaccgc tatttcttgg ataaggtagc
   115081 gaccaagatt ctcgcttttg aggatggcaa gattcgtcct ttctttggtc attacaccga
   115141 ctatcttgat gaaaaagctt ttgaaacaga tatggccaat caagtgcaaa aggtcgaaaa
   115201 ggaaaaagtg gtcaaggttc gagaagacaa gaaacgcatg acctaccaag aaaagcagga
   115261 gtgggcaagt attgaaggtg atattgaaac cttggaaaaa cgtatcgctg ctattgaaga
   115321 ggaaatgcag gctaacggct ctgactttgg taagctggct actctccaaa aagaattgga
   115381 tgagaaaaat gaagcactcc ttgaaaaata cgaacgctat gagtatctca gtgaatttga
   115441 tagttaagac tattcgaaaa tcaaagtgca aactatgtcg gcttcacatt gccgactcaa
   115501 gtacagcctg tgaccggctt cctaatttgc actttgattt ttattgagta taaacgaata
   115561 gaaaaatccc gtctcatgaa aggatttctc tattcttttt tggtttcttg atgaaagata
   115621 ttttgccagg tttcgtggcg acgccagata ctggtatgga tgataccatc taactcatag
   115681 cagataagtt tggttttttg actgatggaa gtaatttgaa tgtccttgat agcagaattt
   115741 aactcttttt tggtcttata agcctcttta tccatctgct ctccatcttg gcgaatatag
   115801 acaaaatcat cagtcaagag ttcttctagt tggtttcctt ggtcgatcaa ttgttcacgc
   115861 ataagcaatt ttttatagac attgtctaaa atttcatcct cagggatagg tgctggttcg
   115921 atatggacat cggtatcaaa gacgccaaaa cgctcctcca gcatagactc gacctgatcc
   115981 gcgatttcat ggctttcaaa aacagacaag tcaggattca tctctagtgt aatatccagg
   116041 tagatgttgc taccgtaggt gcgacctctt tgcgatttga ccttgctgat tttgggaatt
   116101 tccatgatag ccttttggta gtcctcgagc aggcggtcgt caaagccatc tgaaagacta
   116161 aaggaagact cgatgaagat atcataggca gtcttcaaga taaagaaagt gatgatgata
   116221 gcaaccagtt tatccacaat cggataattg aaactactag ctaggatggc aatggcggtt
   116281 ccaagtgagg taacagcgtc agaaagattg tccttagcag ctgccttcag cgccttggag
   116341 ttggatttct tactgaggcg agtattgtag agatagacca caaacataat cgctgcagaa
   116401 atgattccta gagttgcacc aagaggatca atgaccgttt cttcccgact gagaatcttt
   116461 tgaatggtat ctcttagaac atcgaaaccg acatagaaca tgatgataga agtgatcaag
   116521 cttgccaaat cttcaatctt ccaatgacca aaacggtggt cacggtctgc aggctggcgc
   116581 gccatccgaa tcccgattaa gagggccaca tttccaatga tgtccgatac gttattaaaa
   116641 ccatcggcca ccaaactgga tgaatgaagg agatgaccag ttgctaattt ggctgcagac
   116701 aagatcaaat aggtcgaaat actgataatg gctccacgct cagctaactt gagatttgag
   116761 atagattgct tcattcaact tcctttctag tcacatagca ttctaccatt atactggttt
   116821 tcaaggaaaa attcaaataa ggcagttttt actctttgaa aactccccaa aatttggtat
   116881 aatggtacta ctcaagggag tagctggcag aaacctgtga tagtgtcgtc attccgaatt
   116941 ttatgctgaa aagtatgctt tccggcccta tcttaaacag cgagacttgt tatgattaac
   117001 aggtctcttt ttgtttgtcg tgaaaagata tgacagaaag agagtctgtt ttgcacacaa
   117061 tgtcaaggag gagacacatg tcaaaagaac aaaaacgcca agcgttttat actcagagcc
   117121 ctgaagaggt cttgcaggct gtggatgcga ccgagcaagg tttgtcatca agtgaggcgg
   117181 aaaagcgcct tgccgaattt gggcacaatg aactcgaaga aggcgagaaa cgatcaatct
   117241 tggtcaaatt catcgagcaa tttaaggatt tgatgattat catcctagtt gcggcagcaa
   117301 tcttgtcagt cgtgacttct ggtggggaag atatcgcaga tgccattatc atcctagctg
   117361 tggttatcat caacgctgcc tttggtgttt accaagaagg aaaagctgaa gaagctatcg
   117421 aagccctcaa atccatgtct agtccagttg cccgcgttct tcgtgatgga cacatggcag
   117481 agattgactc taaagaattg gtaccaggcg atatcgttgc ccttgaagca ggtgacgtgg
   117541 taccagcgga cctacgtttg ctagaagcca actctcttaa aattgaagaa gcagccttga
   117601 caggtgaatc tgtaccagtc gaaaaagact tgtcagtcga tcttgcgaca gatgctggta
   117661 ttggtgaccg tgtcaacatg gccttccaaa actcaaacgt aacctatggt cgtgggatgg
   117721 gtgttgttgt caatacaggt atgtatactg aagttggtca tattgctggt atgcttcaag
   117781 atgcggatga gactgataca ccactcaaac aaaacttgaa caacctttct aaggtcttga
   117841 cctatgctat cttggtcatt gcccttgtta cttttgtagt gggtgtcttc attcaaggga
   117901 aaaatccact tggtgagttg ttgacttctg ttgcccttgc cgttgcagcc attccagaag
   117961 gacttcctgc tatcgttacc atcgttcttt ctcttggtac tcaagttttg gccaaacgac
   118021 attccatcgt tcgtaagttg ccagcagttg aaacacttgg ttcaactgaa atcatcgctt
   118081 ctgataagac tggtacgctg actatgaaca agatgacagt cgaaaaagtc ttctacgatg
   118141 cggttctaca tgactcagct gatgatattg aactaggtct tgaaatgcca ctacttcgtt
   118201 cagttgtctt ggccaatgat acgaaaatcg atgtggaagg taacttgatt ggtgacccaa
   118261 ccgaaacagc ctttatccaa tatgccttgg acaagggcta tgatgtcaaa ggtttcttag
   118321 agaaatatcc tcgtgtagct gaattgccat ttgactctga ccgtaagctc atgtcaacag
   118381 ttcacccatt gccagatggt cgtttccttg tagcagtcaa gggtgcgcca gaccaactct
   118441 taaaacgttg tcttcttcgt gataaggctg gggatattgc tccgattgat gagaaggtta
   118501 caaatctcat tcatacaaac aattctgaaa tggctcatca agccttgcgt gtccttgcag
   118561 gtgcttataa gattatcgat agtattccag aaaatctcac ttctgaagag cttgaaaatg
   118621 atttaatttt tactggtttg attgggatga ttgaccctga acgtcctgaa gccgctgagg
   118681 ctgttcgtgt ggctaaggaa gcgggaatcc gtccaattat gattacaggt gaccaccaag
   118741 acacagcgga agccattgcc aaacgtttgg gaatcattga cgcaaacgat acagaaggtc
   118801 acgttttaac tggtgctgaa ctcaatgaac tgtcagatga agaatttgaa aaagtcgttg
   118861 gtcaatactc tgtttatgcc cgtgtgtctc cagaacacaa ggttcgtatc gtcaaggctt
   118921 ggcaaaaaca aggtaaagtc gttgccatga caggtgacgg tgtcaatgac gcgccagctc
   118981 tgaaaacagc cgatatcggt atcggtatgg gaatcactgg tacagaggtt tctaaggggg
   119041 cttctgacat gattcttgca gatgataact ttgcgactat tatcgtcgca gtggaagaag
   119101 gacgtaaggt cttctcaaac attcaaaaga ctattcagta cctactttct gctaatactg
   119161 ctgaagtatt aaccatcttc ctatcaacct tgtttggttg ggatgtcttg cagccggttc
   119221 atcttttgtg gatcaacttg gtaacggata ccttcccagc tatcgctctt ggtgttgaac
   119281 ccgcggagcc tggtgtcatg aatcataaac cacgtggacg caaggcaagc ttcttctcag
   119341 gtggtgtttt gagttctatc atttatcaag gtgtactcca agcagctctt gttatgagtg
   119401 tttatggcct tgcgattgct tacccagttc atgtgggtga caatcatgct attcatgcag
   119461 atgccctaac gatggccttt gcaacccttg gtttgattca gctcttccat gcctacaatg
   119521 tcaagtctgt ctaccaatcc atcttgacag ttggcccatt caagtctaag acctttaact
   119581 ggtccatctt ggtatccttt atccttctca tggcaacaat cgttgtagaa ccgcttgaag
   119641 gaatcttcca cgtaaccaaa ctagacttgt cacaatgggg aattgttatg gctggaagct
   119701 tctcaatgat tatcatcgtc gaaatcgtta agtttattca acgcaaactc ggttttgaca
   119761 agaatgcgat ttaagggagg tttcggatgt cagcatatca attaccgacc gtatggcagg
   119821 atgaagctag taatcaagga gcttttacgg ggctaaacag acaaacagca ggtgcccgtt
   119881 tcgaacaaaa cttgccaaaa ggagaacaag cttttcagct ttattcactg ggaacaccaa
   119941 atggtgtgaa ggttactatc ttattggaag aattactaga agctggtttt aaggaagcgg
   120001 cttacgactt gtataagatt gctatcatgg atggggatca attcggatca gactttgtga
   120061 agctcaatcc aaattccaag attccagcct tattggacca gtcaggtact gaagatgtaa
   120121 gagtctttga gtctgctcat attcttcttt accttgctga gaaatttgga gcctttttac
   120181 caagtaatcc tgtggaaaag gtagaagttt tgaattggct attctggcaa gcaggtgcag
   120241 caccttttct aggtggggga tttggacatt tcttcaatta tgctcctgaa aaattggaat
   120301 atcctattaa ccgttttacg atggaagtga aacgccagtt ggatttattg gataaggaat
   120361 tggctcagaa accttatatt gcaggcaatg actatacgat tgcagatatt gctatctggt
   120421 cttggtatgg acagttagtt caagaaaatc tttaccaagg ttctgcaaaa ttcttggatg
   120481 cctcaagtta tcaaaatcta gtaaaatggg cagaaaaaat tgccaatcgt ccagctgtta
   120541 agcgtggctt ggaagtaact tatacagaaa ttaaatagca aaaaagtcat cttcggatgg
   120601 ctttttgcta cagttgaggg aaagggtttg cagttatcgg cttttgtgct ataattgcta
   120661 taatatagta aaaagcaaga ggagtgtgag gaagtggaaa agaaaattgt gaaggataac
   120721 ttatttttat ctcaagtgtc tcagccggca agtcaggagg acctttatct tgccagagat
   120781 ttgcaggata cactcttagc aaatcgtgat acctgtgttg gtctagctgc caatatgatt
   120841 ggggtgcaga agcgcgtgat tatctttaat cttggcttgg ttcccgtggt catgtttaac
   120901 ccagtgcttc tgtcctttga aggatcctat gaggcagaag aaggctgttt gtccttggta
   120961 ggtgtgagat caactaagcg ttatgaaacc ataaggcttg cctatcgtga cagcaagtgg
   121021 caggaacaga ccattacctt gacaggcttc ccagctcaga tttgccagca tgagctggat
   121081 cacttggaag gacgaatcat ttaggaggaa agcaaatgaa acgaatagtc tttgaactta
   121141 tttttatcgc aacgacctgg tatatctttt taccgcccct taacctgacc agctgggaat
   121201 ttctcttctt cctctgtggg catttgttag ttgtggcaat cttatttggc tttggcaagg
   121261 ggataaacct tgtcaaaacg gttcatgtgc gccacggtaa ggcggaagct gccttaaatc
   121321 ttgagggttt caaaatcaat cggttaggga aaattctgtt agcttcgatt ggaggaattc
   121381 ttctcttggc agctttggtt tccttggtaa cttccagcat gtttcaggct aaaaattatg
   121441 ccaatgtagt cacggttacg gaaaaagact ttactgaatt tcctaggagt gacaccagta
   121501 aggttcctat cctagataga agtactgctg aaaaaattgg agaccgctac ttgggttccc
   121561 taaccgataa ggtgtcgcaa tacgtagcgg cagataccta tacccaattg acaattgatg
   121621 ggaaacctta tcgggtcaca ccactagaat atgcagaccc tatcaaatgg tttaacaatc
   121681 aagccaaggg aatcggtgag tatatcaagg tggacatggt aactggaaat gcggatttgg
   121741 tggacttgaa gacaccaatc aagtattcag actcggagta ttttaaccgt gatgtcaaac
   121801 gtcacctgcg cttgaagtac ccgaccaaaa tctttaaaac tccatctttt gaggtggacg
   121861 atgagggcaa tcctttctat gtagcaacgg tttaccaaaa gcaatttgga cttgctgttc
   121921 ctcgtcctgc ttcagtcatt atcttggatg ctacaaatgg agaaaccaag gaatacagct
   121981 tatcagatgt tccagaatgg gtggacagga tctatccagc agaggaaacc attgagcaaa
   122041 ttaactacaa cggcaagtac aaggacggtt tcttgaatgc catgatttcc aagaaaaacg
   122101 tgacccagac taccaagggc tataattact tgtctatcgg taatgacatc tatctctaca
   122161 caggtgtgac gtcggctaat gcggatgaga gtaatcttgg tttcatcctt gaaaatatgc
   122221 gaacaggaga aatcactaag tatagcttgg cttctgcgac agaagaatca gcccgtgaat
   122281 cagcagaagg tgctgttcag gagaaatcct acaaagcaac cttcccaatc ctcatcaacc
   122341 tcaatgacaa gcctctctac atcatgggct tgaaggacaa tgctggcttg gtcaaagagt
   122401 acgccctggt agacgcagtc gagtaccaaa atgttatcgt tgctactaca gtggaagaga
   122461 tgctcagcaa gtatgccaat aaaaacgacc ttgaaattga caatgcaacg acagaaagca
   122521 tcaatggagt agtagcagac ctcaaatcag ctgttatcaa gggagacact gtctacttct
   122581 ttaaagttga tggcaagata tacaaggtca aggcttcagt atccgatgac cttccttacc
   122641 ttgaaaatgg taaaaccttc gaaggtcaag taggaaaaga caattatctc aagaccttta
   122701 aagtacaata atactcttcg aaaatctcta gctctatctg caacctcaaa acagtgtttt
   122761 gagcagcctg cggctagttt cctagtttgc tttttgattt tcattgagta taaaaaaggt
   122821 ttatttaata aatatatgtt ataataaggt aaattaagcc taatggagga caaagaaatg
   122881 ggtttttatt tgatggttgc ttcaatgcta ctcggactgc tcgctttgaa gataggtttt
   122941 tctcagttca aggagaaaaa agataaattc ttatctatct taacaagttt agctggcaca
   123001 gcccttgttc tcgtggctgt ctggttagga tggcccaaat aaatagaaaa acctcggtca
   123061 aaccgaggtt tttcaaatga atttcttggt tgtggctaaa aaatatgcta cactatcaat
   123121 atgaaaattt taatcccaac agcaaaagaa atgaacacag acttgccaag tatcgaggca
   123181 attcctttaa aaccagaaag tcagaccgtg cttgatgcct tggctctcta ttctgccagt
   123241 caattggaga gtttctacaa ggtatcagct gagaaagcgg cggaagaatt tcaaaatatc
   123301 caagctttga aaaggcaaac tgctcaacac tatccagcct tgaaactttt tgatgggctt
   123361 atgtaccgca acattaagag agataagctg accgaggcgg aacaagatta tcttgaaaat
   123421 catgtcttca ttacctcggc tttgtacggt gttgttccag ccttgtcacc catggctcct
   123481 caccgtttgg attttttgat gaaattaaaa gtcgctggta agactttgaa gagccattgg
   123541 aaggcagtct atgatgaagc tctgaagaag gaagaagtga ttttctctct cttgtcatca
   123601 gagtttgaga ctgtattttc taaggaaatc agagcaaaga tggtgacctt caaattcatg
   123661 gaggatagag gcggtcagct gaagattcac tcaactatct ccaagaaagc gcgcggggcc
   123721 tttctaacag ctttaataga aaatcaagta caaactgtgg gggaagcacg tcgcttgaac
   123781 tttgctggat ttgtttaccg agaagatttg tcacaaccac agggattggt ttttgtaaag
   123841 gaagtataga aatcagatat tttgtatttg gcaatatgta tcatcagctg ttttagttta
   123901 taaatgagaa aaaaagcgaa caagctagtc ttctgagtgt cagaaaagta gtcttgttcg
   123961 cttttattat gttatactct tcgaaaatct cttcaagcca cgtcagcgtc gccttaccgt
   124021 atatatgtca ctgacttcgt cagttctatc tacaacctca aagcagtgct ttgagcagct
   124081 tgcggctagc ttcctagttt gctttttgat ttttattgag tgttagttac ttgatagctt
   124141 cgaccaagtc ttgagcttgt ttttcaagtg agtttaggac tgtttcttca agaaccaatt
   124201 ttccgtctgc ccaggcagag tcattaacac gtgcagcagt gaaatcacca acgccttgtg
   124261 tacggataaa tggcaagagg tctttgtaga tagcgaaaag ttgatcgtgc cctgcattgg
   124321 ctacagatga tactgtgaca aacttgtctt gaagggcaga aacgccacgt gtatcagaca
   124381 agtcaagggc acgagatagc cagtcaagca agtttttcac tgtaccaggg atagagaagt
   124441 tgtagactgg agagaaaatc cagatagcat ccgcaacgag aactgcttca cgagcggcag
   124501 ctacagctgg atgtgttggg acttccaaat cttggctgaa gagagggagg gctgaataat
   124561 caaggtagct aacttccgct ttactagcaa gtgctttctc agcttcgagc gccatttggt
   124621 ggttgaaaga accttgacgt agtgatccga cgataaataa tactttttta gacatgatgt
   124681 gtctcctttt tcttaaaatt tcgagaactc tctcgttgtt ataaaatata ttacaacaaa
   124741 acaaaagaac ttgcaagaaa tttgctcaga gtttatttga aaattgtaaa atttcggaaa
   124801 ctctagtcat ttgtgactga aaaagtaaga actgtttcac tttcaaaatc ggttttgttt
   124861 gaagggagaa atagaattgg ttgctcaaag cacagctttg aggttgcaga taaagctgac
   124921 gtggtttgaa gagattttcg aagagtattc ttatattcac ttgtaataaa gcttaataga
   124981 tggtaaaata gacgagtgaa aaaaagacaa aacaaagcaa aaaataatct actgtggcag
   125041 tatggtctag ggatgacgat tttgtttgtg gttatcagtg gttcctttct gtatatggtt
   125101 tctcttagca tgaaacccta tcaaacagct aaaagtgaag gagaaaaatt agctcagcag
   125161 tatgcaggat tagagcaggt cgatcaggtt gatttataca atggcttgga atcttattac
   125221 agcgttcttg gtcgtaataa acagcaagaa gcgcttgctg tcctgattgg taaagatgat
   125281 cataagattt acgtttatca gctaaatcag ggtgtttcac aagaaaaagc agaaacggtt
   125341 tctaaggaaa agggagctgg cgaaattgac aagattatct ttggtcgtta tcaagataag
   125401 ccaatctggg aagtcaagtc aggatctgat ttttatctag tagattttga aacaggagca
   125461 ttggtcaaca aggagggcct atggaattat ccaaccgtgt tttagaaatg gaagaaagtg
   125521 tgactttggc tgctggagcc cgtgccaaag cactgaaggc tgagggtaga gatattttgt
   125581 ctctaacctt gggtgagcca gatttcacta ctcccaaaaa tatccaagat gccgccattg
   125641 catcgattcg agatgggcgt gcttcttttt atacagtaac ctcaggtctg ccagagctta
   125701 aggcggcggt caatagctac tttgagcgct tttacggcta ttctgtagcg tcaaatcaag
   125761 tgacagtcgc tgcgggagcc aaatattctc tctatacctt ctttatggct gtggtcaatc
   125821 caggtgatga agtcatcatc ccaaccccat actgggttag ctatggagat caggtcaaga
   125881 tggcagaagg cgttcccgtc tttgtttctg ctaaggaaga caatcacttt aaggtgaccg
   125941 tagagcagtt agaagcagct cgcactgaca agaccaaggt tttggtgctg aattcgccat
   126001 ctaatcccac aggtatgatt tacacccgtg aggaactctt ggcaattgga aactgggctg
   126061 tagaaaatga tattctcatc ctagcagatg atatctatgg ccgcttggtt tataatggtc
   126121 atgagttcac accgatttct agcctatcgg aagcgattcg caagcaaaca gtggtcatca
   126181 atggtgtgtc taaaacctat gccatgactg gttggcggat tggttatgcc gttggagaag
   126241 cagacattat cgctgccatg tccaagattg caggtcaaac aacttcgaat ccgtcagcag
   126301 tagcccaata tgcagcagtt gaggctctat caggtgagca agatactgta gaaagcatgc
   126361 gtcaggcctt tgaggaacgt cttaatacca tctatcccct ccttgcagaa gtgccaggat
   126421 ttgaagtggt caaaccgcaa ggggccttct atctcttccc aaatgtcaaa aaggccatgg
   126481 agatgaaagg ctacacggat gtgacagact ttacaactgt tatcttagaa gaagccgaag
   126541 tggccttggt aacaggagct ggatttggag caccagaaaa tgtccgcctc agctatgcga
   126601 cagacctaga cacgcttaaa gaagcagtcg aacgcttgaa agcatttatg ggtagtgaga
   126661 atgattgatc attttgagat taaggtaaag gatttacaaa tttcagaagg attttatagg
   126721 agttttctcg ctcctttgga ctataaattg gcttttaaga ctagttctct aattagtttt
   126781 ctatccccga acagccctca tcctggtggt gatttttggc tgactcaggg aacacaagat
   126841 cctgttcatt ttgctttttt agcagaaaat aaggaagaag ttcaggcttg ttatgaggct
   126901 ggcttagagg caggtgggcg agacaatggg gctcctggtt atcgaagtga gcatccgatt
   126961 tactatgctg cttttatgat tgacctggat gggaacaata tagaggtggt ttgccataaa
   127021 gaataaaaaa gaaaaggaaa aataatgaca aaacgtgtaa cgattattga cgtaaaagac
   127081 tatgttggtc aggaagtgac gattggcgct tgggttgcca acaaatcagg aaaagggaaa
   127141 atcgctttct tacaattgcg tgatggaaca gccttctttc aaggtgtggc ttttaaacca
   127201 aactttgtcg aaaaatttgg tgaagaagtg ggacttgaga agtttgatgt tatcaaacgc
   127261 ttgagccaag aaacgtctgt ttatgtgaca ggtattgtca aagaggacga acgttctaaa
   127321 tttggctatg agttggacat cacagacatc gaagtgatcg gtgaatctca agactaccca
   127381 atcacaccaa aagaacacgg aacagacttt ttgatggata accgtcactt gtggctacgc
   127441 tctcgtaagc aagtagctgt gttgcaaatc cgtaacgcta ttatctatgc aacttatgag
   127501 ttctttgaca agaacggttt tatgaagttt gacagcccaa ttctttcagg aaatgcggca
   127561 gaagattcta cagaactctt tgaaactgac tacttcggaa cgccagccta cttgagccaa
   127621 tcaggtcaac tttacctaga agcaggggct atggctcttg gtcgtgtctt tgactttggt
   127681 ccagttttcc gtgctgaaaa atcaaaaaca cgccgtcact tgactgagtt ctggatgatg
   127741 gatgctgagt actcatactt gacacatgat gagtcgcttg acttgcaaga agcttatgtg
   127801 aaagctcttc tacaaggtgt tcttgaccgc gcgcctcaag ccttggaaac cttggaacgt
   127861 gatacagaac tcttgaaacg ctacattgca gagccattca aacgtatcac ttacgatcaa
   127921 gccattgacc tcttgcaaga gcatgaaaat gatgaagatg ctgactacga gcatcttgag
   127981 catggtgatg actttgggtc accacacgaa acttggattt caaaccactt tggtgtgcca
   128041 acatttgtca tgaactatcc agcagccatc aaggccttct acatgaaacc agttcctgga
   128101 aatccagagc gcgtgctttg tgcagacttg cttgctccag aaggctatgg agaaattatc
   128161 ggtgggtcta tgcgtgagga agattacgat gcccttgtcg ctaagatgga tgaacttggc
   128221 atggatcgta cagaatatga attctacctt gaccttcgta aatacggtac agttccacac
   128281 ggaggatttg gtatcggtat cgaacgtatg gtaaccttcg cagcaggaac aaaacatatc
   128341 cgtgaagcta ttccattccc acgtatgttg caccgtatca aaccataaga acaggaaaac
   128401 gcccatgtgg cgttttttcg aattctagtg tttttacttg cgtaaaaaaa ttttttctag
   128461 tataatagtt tattgtgagc gaacctcact taccccttgc aaagtcttgg ggtcattaga
   128521 ccaaaaggag gaacatatca atggctaaat acgaaattct ttatatcatt cgtccaaaca
   128581 ttgaagaaga agctaaaaac gctttggtag cacgttttga ctctattttg actgacaacg
   128641 gtgcaactgt tgttgaatca aaaacttggg aaaaacgtcg tcttgcatac gaaatccaag
   128701 atttccgtga aggactttac cacatcgtta acgttgaagc aaatgacgat gcagctctta
   128761 aagagtttga ccgtctttca aaaatcaacg ctgacattct tcgtcacatg atcgtcaaaa
   128821 ttgacgcgta agaaggtaaa ctatgattaa caatgttgta cttgtagggc gtatgacacg
   128881 tgacgctgag ttgcgttata ccccatcaaa tgtagcagtt gcgactttta ctcttgcagt
   128941 aaaccgtaca tttaagagtc aaaatggtga acgtgaggct gattttatca atgtcgttat
   129001 gtggcgccaa caggctgaaa atcttgctaa ctgggctaaa aaaggctcac ttatcggggt
   129061 gacaggtcgt atccagactc gtagttacga taaccagcaa ggacaacgtg tctacgtgac
   129121 agaggtcgtg gctgagaatt tccaaatgtt ggaaagccgt agtgtgcgtg agggccacac
   129181 aggtggagct tactctgcac caactgcaaa ctattcagca cctacaaatt cagtaccaga
   129241 cttttcacgt aatgaaaatc catttggagc aacaaaccca ttggatattt cagatgatga
   129301 tttaccattc taatggacaa ctaaacttat aaaggagaaa aaacatggct caacaacgtc
   129361 gtggcggatt caaacgccgt aaaaaagttg attacatcgc agcaaacaaa attgaatatg
   129421 ttgattacaa agatactgag cttcttagcc gtttcgtttc agaacgtggg aaaatccttc
   129481 ctcgtcgtgt aacaggaact tcagctaaaa accaacgtaa agtaacaaca gctatcaaac
   129541 gcgctcgcgt aatggctttg atgcctttcg taaacgaaga ttaaagaaaa gacccggttg
   129601 ggtctctttt tcatgagctt gaaaacaaga aagcgaatta agaccccaac gggtcttttt
   129661 tcacaagctt tgaaatgaga gagcgagtta ggctcagtgg ctcccttttt acgagtttga
   129721 aaacaagaga acacattaaa agcacgatgg agctttttca taaatatgtc ttttttctca
   129781 tccaagaaat taaaataaaa atgataaact ttttgaaaat aggggatttg cctactttat
   129841 gatataatgg aaagagttag attgaaagag gtagtgagat ggacgcgaaa ttaagataca
   129901 aggcaaagaa gatcaagatt gtcttttttg atattgatga tacattgcgg aattcaaaga
   129961 cagggtttat tccaactaca attcccactg tttttaaaca gttgcgtgaa aaaggaattt
   130021 taacaggaat cgcctctgga cgtggcattt ttggtgttgt tccagagatt cgtgatctca
   130081 agcctgactt ttttgtaact ttgaatggag cttatatcga agataaaaaa ggtcaggtca
   130141 tttatcagca tcagattgaa aagtcagatg ttgaggagta tatctcttgg gctaagcaag
   130201 aaggaattga atatggcttg gttgggagtc atgatgccaa gttgtcgact cgcaccgata
   130261 tgatgagtga agctatcaat ccaatttatc ccgacttaga tgtagatccc gatttccatg
   130321 aaaaagaaga tatctatcag atgtggactt ttgaagataa gggagatgac ttgcacttgc
   130381 ctgacagtct ctcagacaaa cttcgcatgg ttcgttggca tcaacattcg tctgatattg
   130441 tgccgatttc aggctccaaa gcgacggggg tggaaaaggt tgtggaacac cttggcttga
   130501 aaccagagaa ggtcatggtt tttggagatg gtctcaacga cttggaactc tttgattatg
   130561 ctggaatcag cgttgccatg ggaatttctc atgataaaat caaagaaaaa gcagattata
   130621 ttacaaaaac attagaagaa gatggcattt ttgatgcctt agaagtattt ggtatggtag
   130681 aaaaagaatt gcattttcca caagtagaca ttgaaacagt agaaggtcct cttgcgacta
   130741 ttaagaccaa tcacggagac ttacgtatca agcttttccc tgaacatgct cctaaaacag
   130801 tggctaactt tgtatctctt tcaaaagatg gctactatga tggtgtcatt ttccaccgta
   130861 ttatcaagga ctttatgatc caaggtggag acccaactgg aactggtatg ggtggcgagt
   130921 caatctacgg cgaatctttt gaggatgaat tctcagaaga gctttacaat atccgtggtg
   130981 ctctttccat ggcaaatgct ggtccaaata ccaacggcag ccagttcttt atcgtgcaaa
   131041 accaacacct accttattcg aagaaagaaa ttactcgtgg tggttggcca gaaccgattg
   131101 cagaaatcta tgccaatcaa ggtgggacac ctcacctaga ccgccgtcac acggtttttg
   131161 gtcagttagc tgatgaagca tcttacgctg tcttggatgc cattgctgct gttgagacag
   131221 gagctatgga caagccagtt gaagatgttg taattgaaac tattgaaatc gaggactaag
   131281 atgaaaatcg gtgataagct aaaggggcgt attacaggga ttcagcccta cggtgccttt
   131341 gttgagttag agacgggtga tacggggctg attcacattt cagaaattcg gacaggattt
   131401 attgaaaata ttcatgaaac cttgaaagtc gatgaagagg ttcaagttca ggtagtggat
   131461 ttagatgaat ttacggggaa agccagtctt tctatccgca ctttggagga agaaaagtac
   131521 cagtttccta gacggagacg cttttcaagc gaccgcttta actacggttt tgctcccttt
   131581 cgacgaatgc taccaatctg gactggagaa gccctgcacc atttaaaaaa gaagaagtag
   131641 tttagagttt tatatttttt gtaatgttaa tatgaatttg ctataatagg accatggaag
   131701 aagaacaatt attaaaatca ggagagcgca ttaaccagct cttttcgaca gatatcaaaa
   131761 tcattcaaaa tagagaggtt tttagctatt cggtggatag tgttctctta tcacgatttc
   131821 cacgttttcc taagaagggg ttgattgtgg atttctgtgc tgggaatgga gcagtggggc
   131881 tttttgctag cactcgtact caagcacaga tattgtctgt tgagattcag gagcgtttgg
   131941 cggatatggc tgaacgctct gtccgtttga atggattaga ggagcaaatg caggtcatct
   132001 gcgatgattt gaaaaatatg cctgctcaca ttcaggggag taaggtggat atgattttgt
   132061 gtaatccacc ctatttcaag gtgaatcctt attctaatct gaacgagagt gaacattatc
   132121 tcttggctcg acacgaaatc acgactaatt tggaagaaat ctgtcgtagt gcccagagta
   132181 ttctcaagtc taatgggcgt ttggccatgg ttcatcgtcc tgatcgactt ctggatattt
   132241 tggatacgtt aaaacgacat aatctagccc ctaagcgcct gcagtttgtt tatccaaaaa
   132301 gagaaaagga agccaatatg cttttgattg aggcgatcaa ggatggctca acaagtggct
   132361 ttaaggtctt acctcctttg attgtccaca atgatgatgg ctcttatacg cccgaaatcg
   132421 aagagattta ttatggatca taaggcttat atgtacgttc tggagtgtcg tgatggatcc
   132481 tactatatag gctatacgac tgatatgaga agacgcctcg ctatccacaa tagtgggaag
   132541 ggagccaaat atacacgagc acgcttgcca gtcaaactta tctatgctca aggttttgcc
   132601 agtaaggaag aagccatgtc ggctgaagct cttctcaagc gtaagaagag gccacagaag
   132661 gaagaatttt tatctgaaaa tcaagataga aatttactca gttattttga agaatcgtgg
   132721 ggagtccttt gactcctctt acctttgtca aaaagcgaaa aaaatgctac aataaagaaa
   132781 ataaacaaaa tgaggtatta tcatgtccaa gattctagta tttggtcacc aaaatccaga
   132841 ctcagatgcc atcggatcat ctgtagcttt tgcctacctt gcaaaagaag cttacggttt
   132901 ggatacggaa gctgttgccc ttggaactcc aaatgaagaa acagcctttg tcttgaacta
   132961 ttttggtgtg gaagcaccac gtgttatcac ttctgccaaa gcagaggggg cagagcaagt
   133021 tatcttgact gaccacaatg aattccaaca atctgtatca gatatcgctg aagtagaagt
   133081 ttacggtgtt gtagaccacc accgtgtggc taactttgaa actgcaagcc cactttacat
   133141 gcgtttggag ccagttggat cagcgtcttc aatcgtttac cgtatgttca aagaacatgg
   133201 tgtagctgtg cctaaagaga ttgcaggttt gatgctttca ggtttgattt cagataccct
   133261 tcttttgaaa tcaccaacaa cacacccaac agataaaatc attgctcctg aattggctga
   133321 attggctggt gtgaacttgg aagaatatgg tttggcaatg ttgaaagctg gtaccaactt
   133381 ggctagcaaa tctgctgaag aattgattga tatcgatgct aagacttttg aactcaacgg
   133441 aaataatgtc cgtgttgccc aagtgaacac agttgacatc gctgaagttt tggaacgcca
   133501 agcagaaatt gaagctgcaa tgcaagctgc caacgaatca aacggctact ctgactttgt
   133561 cttgatgatt acagatatcg tcaactcaaa ctcagaaatc ttggctcttg gtgccaatat
   133621 ggacaaggtc gaagcggctt tcaacttcaa acttgaaaac aatcatgcct tccttgctgg
   133681 tgccgtttca cgtaagaaac aagtggtacc tcaattgact gaaagcttta atgcgtaaga
   133741 ttttgggtgt cagctcaaaa tcggaaagtc tagtttgcct tatatcgaaa ggagtttcgg
   133801 ctcctttttt ctaggagtga agtatgttag aaaatggcga tttgattttt gtgagagatg
   133861 ggtcagacat gggacaggcc atccagactt ccacaggtaa ctatagccat gttgccattt
   133921 atttggatgg gatgatttat catgctagtg gacaggctgg tgttgtctgt caagaaccgg
   133981 cagacttctt tgagtccaat catttatacg acctctatgt ttacccagaa atggatatcc
   134041 agtcggtgaa ggaaagagct tgcaaacatc ttggagcacc ctacaatgct tctttctatc
   134101 cagatgcacc tggtttctac tgctcccagt atatagcaga aatcctacct atttttgaaa
   134161 ctattcctat gaaatttgga gatggggagc aggagattag tgatttttgg agggagtatt
   134221 acatagaact aggtctgcct gttcctctga accaagctgg taccaatcct agtcagttgg
   134281 cagcatcgcc tctgttacaa tgtaaagaaa ggaatcttca tgattcagat ttttaatcca
   134341 tctcgtttga cgagacagcc atttttggag aattgatccg ctatctggac cagtatgagg
   134401 atgtgattct acgggaaatt aaggctcaat ttccagatgt tgcagttgat aaactcatgg
   134461 aagagtatat aaaggcaggc ttgattctac gtgaaaataa gcgctattac ctcaattttc
   134521 ctacgcttga atcacttgat agtcttgaac tggatcaaga gatttttgtc agagaagcta
   134581 gtccggtcta tcaagccttg ttggagcaga gttttgagac ggaattgcgc aatcaaatca
   134641 atgcagctat tttagttgaa aagacggact ttgcgcgcat taaaatgact ctgtccaatt
   134701 atttttacaa ggtcaaacag cagtatcctt tgacagaaaa acagcaggag ctctatgaca
   134761 ttttaggaga tgttaatcct gagtatgcac tcaagtatat gacggctttt ttgttgaaat
   134821 ttctcaaaaa agaccagctt atgcagaaat gccgtgatat ctttgtggac agtttggttg
   134881 tcttaggcta tattgtgcaa aatgaagatg gaaagtatga gttggctatc gattttgata
   134941 aggagagatt aactttctac ttagcgtgat ttcttgtttc tgagtacatt gtttgacttt
   135001 ccttagtatt cggtataaac tatatgtaac cggtaacaca tatcggaata aactaaagga
   135061 gacaatcata tgtcacttga aaacaaattg gaacaagcaa caggcgctgt caaagaaggt
   135121 tttggtaaag ttactggaga cagcaagaca gaacttgaag gagctgttga aaaaacagtt
   135181 gctaaggcaa aagacgttgt agaagacgca aaaggtgctg tagaaggtgc cgttgaaggt
   135241 ttgaaaaacg tttttactaa agaataggaa aaaatcaagg gtttcatttt cccttgattt
   135301 tttctattct tataaataat tttctgcgac ggctgtatct cctgggtagg attctttctt
   135361 gccctggatg atttggtaac aatcggctcc cttacccgca ataataactg catctaattc
   135421 gtgatttgtg atagccattg ccgccttgat ggcttcttgg cgatccgcaa tcttctcaac
   135481 aggatgattg atgtagctac taatttcatc tgcaatggcc attgggtctt catagttagg
   135541 gtcatcagca gtcagaaaga cttgaatctc agggtgttga ttgaggagga ggccaaagtc
   135601 cttacgacga ctttctccct tgtttcctgt tgatcccaga accagagcaa tctttccggt
   135661 ttgatgagtt tcaaccacat tgatgagttt tttcagacta tccccattgt gggcatagtc
   135721 gatgaagacc ttggctccat ttttctgagt gaggacttcc atacgaccag gaacgcgggt
   135781 tgcagcgatg ccttttttga tgtcctcaag acttgctccg agacggagac aagcaagtcc
   135841 agcagcaact gcattttctt ggttgaagtt gccaatgagt tggatatcat aatctccagc
   135901 gagtttaccc gtagctgaaa agctaaaggc tttggaattc tcgatttggt tatcaaattg
   135961 gctaccatag aaatcatggt cttgatcttc aacctgttct ttcaagactg agaagtggtc
   136021 catgtcactg ttaatgatga ctgctcggct attttccatc aagagacgct tgtggtagaa
   136081 atagtcttca aagctagggt gttcaatcgg gccgatatgg tctgggctga tattgaggaa
   136141 aactcccaca tcaaaggtta gaccatagac acgtctgacc agataggatt gactggagac
   136201 ttccatgatg aggtgggtac ggtcattttg cacagcctga ttcatcatgt caaagaggtc
   136261 aatactctca ggggttgtca acgctgactt aaagaaagtc tcgccatcaa gagttgtgtt
   136321 catggtcgac aacatagcag gtcgatgccc ttgagataag atgttatagg cgaaataggc
   136381 tgctgttgtc ttacccttag taccagtaaa ggcaaggagt ttgagttttt cctgtggatt
   136441 accatagaac tccatggcaa tcaaactcat ggctttcttt atatcgttca caatgatgac
   136501 agggataccg acttcgtagt ccttttcagc tacataccaa gctaagcctt gtgttatagc
   136561 agaaagaagg tattcttttt taaaggcagc gccttttgca aaaaaaagag tgtcttctgt
   136621 tacttttcgg ctatcgtagc tgatgctatc aaaaacaact ttgctgtagt tgtagtggta
   136681 atgaccttgg tcaataattt cgcgaaaaag gccatctttc tttaaaatat ctaatacagt
   136741 ttcaattttt atcatacttt ctattgtaaa ccgaaagtcg caaatttaca agtaacaagg
   136801 aaaagtttat aatggaagat aaggagtttt tcctagttat caaaattgaa tgaggaatct
   136861 atgtcgcacg aaaacaatca ccagcaggcc cagatgttac gggggactgc ttggctaacg
   136921 gctagtaact ttatcagtcg cctactcggg gctgtttaca ttatcccttg gtacatctgg
   136981 atgggggctt atgcagctaa ggcaaatggt ctctttacca tgggttacaa tatctatgct
   137041 tggttcttgt tggtttcaac agcggggatt ccagttgcgg tggccaagca agttgccaag
   137101 tataatacca tgcgagaaga agaggatagc tttgccctga ttcggagctt cttaggcttt
   137161 atgacaggac taggcctggt ttttgcttta gtcttgtatg tctttgctcc ttggctagca
   137221 gacttgtctg gcgtgggcaa agacttgatc ccaatcatgc aaagcttggc ttggggagtc
   137281 ttgattttcc cgtctatgag tgttatccga ggatttttcc aagggatgaa taacctcaaa
   137341 ccttatgcca tgagccaaat tgctgagcag gtcattcgtg ttatctggat gctcctagca
   137401 acctttatca ttatgaagct cggttcagga gattatctag cagccgttac ccaatcaacc
   137461 tttgctgcct ttgtcggtat ggtagccagt tttgcagtct tgatttattt ccttgcccaa
   137521 gaaggttcac tcaaaagagt ctttgaaaca ggagataaga ttaacagtaa gcgtctcttg
   137581 gttgatacca ttaaggaagc cattcctttt atcctgacag ggtctgccat ccagctcttc
   137641 cagattttgg atcagctgac ctttatcaat agtatgagct ggtttaccaa ctacagcaat
   137701 gaggacttgg ttgtcatgtt ttcttatttc tcagccaatc ctaataaaat cacgatgatt
   137761 ttgatttctg taggggtttc gattgggagt gttggtttgc cacttttgac ggaaaactat
   137821 gtcaaggggg acttgaaagc agcttctcgt ctggttcagg acagtctcac cctactcttt
   137881 atgttcttgc taccagcaac ggttggagtg gttatggtag gagaacctct atatacagtc
   137941 ttctatggta agccagatag tttggctctg ggcttatttg tctttgcagt tttgcagtct
   138001 attattttag gcttgtacat ggtcttgtct ccaatgcttc aggccatgtt ccgcaaccgc
   138061 aaggccgttc tctattttat ctatggttct attgccaagc tagtcttgca actacctacc
   138121 atcgccctct tccacagtta tggtcctttg atttcaacaa ccattgctct catcattcct
   138181 aacgtcttga tgtatcggga tatttgtaaa gtaactggtg tcaagcgcaa ggtgattttg
   138241 aagcgaacca ttttaatcag tttgctgacc ctagtcatgt ttctgttaat aggaaccatc
   138301 cagtggctgt taggattttt cttccaacca agtggacgtt tgtggagctt cttttatgta
   138361 gctcttgtcg gtgccatggg gggtggactt tatatggtta tgagtctgcg tacctattta
   138421 ttagataagg taataggaaa agcccaagca gatcgcctgc gagcaaaatt taagctttcg
   138481 taaggtagca tttataaata aaaggaataa gttgaacaat cttttaggag aacttgaaac
   138541 ttattccttt tttagcgtca aaatagctaa aattatcttt caaaaataga aaatgaggtt
   138601 tttttgattt tttggaaaaa acaattgact aaacaaacca agagttgtat aataaaacaa
   138661 atatttaaag caggaggttc tggaaatgaa aaagtctaag agcaaatatc taaccttggc
   138721 aggtcttgtc ctgggtacag gagttttatt gagcgcgtgt ggaaattcta gcactgcatc
   138781 aaaaacctat aactatgttt attcaagtga tccatctagt ttgaactatc tagcagaaaa
   138841 ccgcgcagca acatccgata ttgttgcaaa tttggtagac gggttattag aaaatgacca
   138901 atatgggaat attattccat cattagcaga ggattggact gtttctcagg acggtttgac
   138961 ctatacctac aaacttcgta aggatgccaa gtggtttact tctgagggag aagaatatgc
   139021 gcctgtaact gcccaggatt ttgtgacagg tttgcaatat gcagctgata aaaaatcaga
   139081 agctttgtat ctagtgcagg actctgttgc tggtttggat gactatatca ctggtaaaac
   139141 aagcgacttt tcaactgtcg gtgtcaaggc acttgatgac caaacggttc aatatacttt
   139201 ggttaaacca gaactttact ggaattcaaa aacacttgca acgatacttt ttcctgttaa
   139261 tgcagatttc ctgaaatcaa aaggggatga ttttgggaag gcggatccat ctagtatttt
   139321 gtacaatgga cctttcttga tgaaagcact tgtctcaaaa tctgctattg aatataagaa
   139381 aaaccctaat tactgggatg ctaagaatgt ctttgtagac gatgtgaaat tgacctacta
   139441 tgatggtagc gaccaagaat cactggaacg taattttaca gctggtgctt atactacggc
   139501 tcgtcttttt cctaacagct ccagctatga agggattaaa gaaaaataca aaaacaatat
   139561 catctatagt atgcaaaatt caacttcata tttctttaat tttaacctag ataggaagtc
   139621 ttacaattat acttctaaaa caagtgacat tgaaaagaaa tcgacccagg aagcagttct
   139681 caataaaaac ttccgtcagg ctatcaattt tgcttttgac agaacatctt atggggctca
   139741 gtctgaaggg aaagaaggtg caacaaagat tttgcgtaac ctagtggttc ctccaaattt
   139801 tgtcagtatc aagggaaaag actttggtga agttgtagcc tctaagatgg tcaactatgg
   139861 taaggaatgg caaggtatca actttgcgga tggtcaagac ccttactaca atcctgagaa
   139921 agccaaggct aagtttgcgg aagctaagaa agaactcgaa gcaaagggtg ttcaattccc
   139981 aatccacttg gataagactg tggaagtaac agataaagta ggcatacaag gagttagttc
   140041 tatcaaacaa tcaattgaat ctgttttagg ttctgataat gtagtgattg acattcagca
   140101 attaacatca gatgagtttg acagttcagg ctactttgct caaacagctg ctcagaaaga
   140161 ctatgattta tatcatggcg gttggggacc tgattatcaa gacccgtcaa cctatctcga
   140221 tatttttaat actaatagtg gaggagttct acaaaatctt ggactagagc ctggagaagc
   140281 caatgacaag gctaaggcag ttggactgga tgtctatact caaatgttgg aagaagctaa
   140341 taaagagcaa gatccagcca aacgttatga gaaatatgct gatattcaag cttggttgat
   140401 tgatagttct ttagttcttc caagtgtttc gcgtggggga acaccatcat tgagaagaac
   140461 cgtaccattt gctgctgcct atggtttaac cggtacaaaa ggggttgaat catataaata
   140521 cctcaaagta caagataaga ttgtcacaac agacgaatat gcaaaagcca gagaaaaatg
   140581 gttgaaagaa aaagaagaat ccaataaaaa agcccaagaa gaattggcaa aacatgtcaa
   140641 ataaaatcta attgtagata agtttgtgta agaagtcttt gtgcttaaaa acgcataata
   140701 tcaggtatat aaaatcctag atgttatgcg ttttgttata ggaagattta ttagatttta
   140761 tcctcaaatt gagttattcc cgactttatc cgttgaaata ttataaggag tatttatgaa
   140821 attaaaatta ttaagagtag atactaaggt gattatgggg agtttcttac ttgttctgtc
   140881 tagtctactt gctttgttgc ttccccttat cttaaagggt ttaatagatg ggagttctat
   140941 tgaaaatata ggttccaaag tatttcaatc gtttttgatt tttattggtc aagccttgtt
   141001 ttcttctatt ggttactatc tgtttagtca atcgggtgaa aaaaagatag caaaaatcag
   141061 gaaaaaagtg atagaggggt tgatttatgc agagaaatcc ttctttgata agagccaaag
   141121 tggggagttg acttctgcca ttgtcaatga catgagtgtc attcgtgagt ttttaattac
   141181 gactttccca aatattattc tgagtttagt tatggtactt ggttccattg tagtcttatt
   141241 tagtcttgat tggaatcttt ctctactttt attcatcact cttccttgta tgatgtttat
   141301 tatcttgccc ctttccaata tcagtgaaaa gtatagtcgt cgtttacagg aggaaattta
   141361 acagggcaat tgactgaaaa gattcaagaa catgaattaa ttaagactaa ccaagcagag
   141421 aaaagtgtac aggatgtttt ggataattgt attgaaaggg tacaaaacaa ttcactgaaa
   141481 tcagataggg ttacttcttt tgagacctcg tttgctctct tatttatctt tgcgactata
   141541 gttgtgatgc taacctatgg gggttatcgg gtcagcgcag gatatatatc tgtgggaacc
   141601 ttggtttcgt ttttgattta cctctttcaa ttacttaatc ctattagtaa tatagctaat
   141661 tttgtaactg tttattctag gagcaaggga tcttcagttg cactggataa cttgcttgca
   141721 gttcctaaag aaaaatttga gggaggaaaa tcggtatcag gacaagggtt gaattttaac
   141781 catgtctatt ttggttatga tgaaaatcga cctgtcttaa aggatattac ttgttcaatt
   141841 ttcaaggggc aaaaattgct tttgttggac catctggatc aggaaaatca acgattgtgc
   141901 gtttgttaga gcggttttat aaaccgcttt caggagatat tctaatggag caatcaagta
   141961 tatatgattt taacttaaaa gaatggagaa gtaaaatcgc ttgggtttca caaaataatg
   142021 cagtcttatc tggcagtatt cgtgacaatc tttgtctcgg tttgaatcgc ttagtaactg
   142081 atgatgaatt gatgaaagtg ctagacttag tatcactagg tgatgagatt cgctccatga
   142141 aagagggact agatactgaa gttggtgaac gcggacgatt cttgtcaggg gggcaaagcc
   142201 aaagacttca aatagctaga acctacttaa aagatgctga aattcttata tttgatgaag
   142261 ctactgctaa tcttgatgcg gattctgagt atgcgattat cagtagcctc tattctgtat
   142321 taaaggagaa gacggttgtg attatagcgc atagtttgtc aacggtaaaa gatgtggatt
   142381 gtattttctt cttagaggag gggaaaatca ctggctcagg aactcataag gaactactgg
   142441 aaaatcatga gcgttatgct cgttttgtgc aggagcaaat gatagagtga agtgtctttt
   142501 gagattcacc attttatagt ctattaaagg gagcaggaaa aactcccttt ttatatagtt
   142561 tgaaactata actagctctt gaaaagaaga aaatgagttg atgaaaataa gtggtacaat
   142621 agttactata gatttggagg tattgtatga gcaaggaatt acacattaac acaattttgg
   142681 cccaggcggg tattaagtca gatgaagcga caggtgcatt ggtgacaccg cttcattttt
   142741 caacgaccta tcagcatcca gagtttggtc gatctactgg gtttgactat acgcgcacta
   142801 aaaatccaac tcgtagtaag gctgaggaag tcttggcggc tattgagtca gcagactatg
   142861 ccttagcgac tagctcaggg atgtcagcta ttgtactggc ctttagcggc tttccagtag
   142921 gaagtaaggt cttggcagtg cgtgatcttt acggcggttc ttttcgctgg tttaaccaag
   142981 tggagcagga aggtcgtttc cattttacct atgccaatac agaagaagag ttgattgccg
   143041 agttagaaaa ggatgtggat gttctctata tcgaaacccc aaccaatccc ttgatgttgg
   143101 aatttgatat cgaaaaacta gcaaaattgg ctcatgctaa gggtgccaaa gtggtggtgg
   143161 acaatacctt ctatagccct atctaccaac gtccgattga agatggagca gatatcgttc
   143221 tccattcagc aaccaagtat ctagcaggcc acaatgatgt cttggctgga gtggttgtga
   143281 ccaatagttt agaactatac gagaagcttt tttacaatct taatacaaca ggggcagtct
   143341 tgtctccatt tgacagctat cagttgcttc gtggtctcaa gaccttgtct cttcgtatgg
   143401 agcgctcaac agctaacgcc caagaagtgg ttgccttttt gaaggattct ccagcagtta
   143461 aggaagttct ctacactggt cgtggaggca tgatttcctt taaagtagcc gatgaaacac
   143521 gcattcctca tattttgaac agtctcaagg tcttctcttt tgcggaaagt ttgggtggag
   143581 tggaaagtct tattacttat ccaacgactc aaactcatgc tgatattcca gcagaggtac
   143641 gccattctta tggtttgaca gatgacctct tgcgtttgtc tattgggatt gaggatgcta
   143701 gagatttgat tgcagatttg cgccaagcca tagaaggata agacaaagat gggaaaatat
   143761 gattttacaa gcctgcccaa ccgtttaggg caccatacct ataaatggaa agaaacagaa
   143821 acggatagtg aagttctacc agcttggata gcggatatgg actttgtggt cttgcctgaa
   143881 atccgccaag ccgtgcaaac ttacgcagac caactggttt atggttatac ctatgccagt
   143941 gaagacttaa ttaaggaagt tcaaaagtgg gaagctacac aatacggtta caactttgac
   144001 aaagaggctc ttgtctttat cgagggtgtg gtaccagcca tctcaacagc tattcaaacc
   144061 tttacaaaag aaggcgaggc ggttttaatt aacacgcctg tctacccacc ctttgctcgc
   144121 agtgtcaagt tgaataatcg tagattgatt actaattcct tagtggaaaa ggatggtctg
   144181 tttgagattg actttgacca acttgaaaag gatttggtgg aagaggaggt taaactctat
   144241 attctttgca accctcacaa tcctggtgga cgtgtttggg aaaaagaagt gttggagaag
   144301 attggccaac tctgccaaaa acacggtgtt ttgttagttt cggatgagat tcaccaagat
   144361 ttgaccctct ttggtcacaa acaccagtct ttcaatacca tcaatcctgc cttcaaaaat
   144421 tttgctatcg tcttgagcag tgccactaaa acatttaata ttgctggaac aaaaaattcc
   144481 tatgcagtca ttgaaaatcc taagttgaga ctagctttcc agaaacgcct gttggccaat
   144541 aatcagcatg aaatttcagg cttgggttat ttggcgacag aagctgccta tcgatacggt
   144601 aaagattggc tagaggaact caagcaagtc tttgaagacc acatcaatta tgtggtggat
   144661 ctatttggaa aagagactaa aatcaaggtc atgaaaccgc aaggtaccta cttgatttgg
   144721 cttgactttt cagcttatga cctgactgat gaaacattgc aagagttgtt gagaaatgaa
   144781 gccaaggtta tcctcaaccg tggtttggat tttggagagg aaggaagtct ccatgcccgc
   144841 atcaatatag ctatgcccaa atctctgttg caagaagtct gtcagcggat tgtggctact
   144901 tttgccaaac gttaaaaatc cagccttcta ggagaaaagt cttcctagaa ggctattttc
   144961 ataggcgaaa atatggtata ataaaaagat aaggtaaagg tgaaaatatg gctaaattga
   145021 ttccggggaa aattcgtatc gaaggtgttg ccctttatga aactggtaag gttgatatca
   145081 tcaaggaaaa gaacaatcgg ctctacgctc gcgttgcaga agaagaactg cgctatagtt
   145141 tagaggatga tttggttttt tgtgcctgtg atttttttca aaagaggggt tactgtgtgc
   145201 atttggcagc gctagagcat tttctgaaaa atgatgagcg tggtcaggaa atcttgtgga
   145261 gtctggaaga aggtcatgaa gaaaaagagg ctgttgaaac caaggtgacc ttgggtggca
   145321 agtttttgga tcgaatttta tctccaaaat cagaatgcgc ctatgagtta tcagctgtgg
   145381 gtcaggtgga agcaggaacc aatcatatct tgtggactct gagaatcggc caaatcaata
   145441 gccaaaaata ctatgtcatt cgggatattc cacttttttt aaggattgtc gagcagagaa
   145501 agtcgtatat gattggcaag atttatgagg agtctctttc ttgggaagcc tttgatgatg
   145561 ccagccaaga acttttgact ttcttgcacg gactaacgga ggaagggctg gtttcagacc
   145621 tctttttcca aaaccaaggt cggcacctct ttttccctct gacctttttt gagcagggtg
   145681 tgaatttact gatggccttg ccccattttc aatttgacca tcaagtggat agctaccaaa
   145741 ccctgctttt tcaggatatg catgctgatg ccaatctatt tgcctttaca gtaacagaat
   145801 actcggacta ttttgaaatg gaaatcagtg agagtcctag ggtcaatgtc ttttatcagg
   145861 gagcagtact tttccataaa ggtcaggttt attttttaac agaccagcag atgcgtcttc
   145921 tcaaggaaat taaagcgtta cctgtgggtc aacaaggaaa gaaatacctg caatttgata
   145981 gcagtgatcg agacaaattg gcctcctgtc tgactctttt tatccagatg ggcaccgttt
   146041 cagctccaga acgtctacaa atcaaaactt ttgcgccctc tttttacttt gacagggaag
   146101 aagataatcg gattcgttta gaaattcagt ttgattatgg aaatagacag gtatctagcc
   146161 gacaagagct agaagaatta ccattttcaa gtgacgcgga cttagaagaa agaattttcc
   146221 aagtctgttt ggctgcgggc tttgaagccg attttcaatc ttggcgtcag gccttaaaag
   146281 cggagtctgt ctatcatttt tttcatgata tcattccagt ctttgaaaaa ctcgggcatg
   146341 ttgacctatc agataaacta gaagagcttt atagcctagc gagtcctcag gtgcagattg
   146401 cctccaaggg aggtctcttg gaaatccagt ttgattttca agatattgcc caggaggaaa
   146461 tcgaccaagc catgcaggcc ttggttgcca atcaggattt ttatattgat tcgtctaatc
   146521 aagtttactt tttcgatgaa gaaaccaaga aaattcgcca aaatctacag gaactggggc
   146581 aatttgaatt aaaagatggg accttgcagg ctcggaaatc cttggcctac agtttagctc
   146641 atctctttga agggcgagac cgtgtttctt tttcacaaga attccagaat ctggcccagg
   146701 atttgacaca tccagaggac tttcctcgac aggcaactca ggttcaggct gacttgcgag
   146761 attatcagga aaagggaatt ggctggttgc agatgctcca tcattatggt tttggtggga
   146821 ttttggctga tgatatggga cttgggaaaa cccttcagac cattgctttt ttgactagtc
   146881 aagtgacaaa agaaagtcgg gttttgattc tcgctccgtc aggtttgatt tacaactggg
   146941 cagatgagtt tcagaaattt gccccacagt tggatgtggc tgttgttcat ggtttgaaag
   147001 caagtcgtga ggagattctt gccgagagcc atcaaatcta tgtgactagc tatgccacct
   147061 tccgtcagga cagtgagttt tatcagggga tggcctttga cttccttttc ttagatgagg
   147121 ctcaggtcat gaaaaatgcc cagaccaaga ttgcccagac cttgagacaa tttgtggtgc
   147181 cgtcggtctt tgccttgtca ggaactccga ttgaaaacca tctgggtgag ttgtggtcta
   147241 ttttccaaat cgtcatgccc ggacttttgc caagcaagaa agaatttatg aaattgccag
   147301 cagagcgagt ggctcagttt atcaagcctt tcgtgatgcg acgcaagaaa gaagaagttc
   147361 tgactgaatt gccagacttg attgaggtgg tttataaaaa tgaactggaa gaccagcaaa
   147421 aggctattta ccttgcccag ttacaacaga tgcgagacca tctggctcaa gtgtcagaac
   147481 aggaatttca gcgaagtcgt gtggaaattt tatctggttt gatgcgcttg cgtcaaatat
   147541 gtgacactcc tgccctgttt atggaagatt atcagggagc cagcggcaaa ctagatagtc
   147601 tccgagatct actggtacag gtggcagacg gcggacaccg tgtcttgatt ttctctcagt
   147661 tcaagggaat gttggaaaaa attgaacaag aactgccaga cttgggcctg acatccttta
   147721 aaattacggg tttaacccca gccaaggaaa gacaagacat gaccaaggcc tttaaccaag
   147781 gagaaagaga tgcctttctg atttccctca aggctggtgg ggtcggtctg aacctgacag
   147841 gtgcagatac agtgatcttg gttgaccttt ggtggaatcc tgcggtggaa gcgcaagcca
   147901 ttggccgtgc ccatcggatg ggtcaggaag aaacggttga ggtctatcgc ttggtgacca
   147961 agggaaccat tgaagaaaaa attcaggaac tccaagaaca aaagaaacat ctggtgtcac
   148021 aagtattgga tggcacagag tcacgtggta gtctgaccct agcagaaatt agagaaattt
   148081 tgggaatttc tgaagccagc acttgaaaaa tcaagacaat acgctataat gaagtgttga
   148141 aaggaaatag aaaatgaaac aagaacgatt tccattggtg tcagatgacg aggtcatgtt
   148201 gactgaaatg ccagtcatga atctctatga tgagtctgat ctgatcagta atatcaaggg
   148261 tgagtatcga gataaaaatt atttagaatg ggctcctatt actgaagaaa aaccagtaaa
   148321 accgattgaa aagcaagtcg aaaaacctaa aaaggctcct ttaggggtta aaaaagaagg
   148381 aaagagctat gcggaggtgg cgcgtgaaga agcgcgtgcg gacttgaaaa agaaacgctc
   148441 tgctaactac ctaactcagg atttcagcct tgcgagacgt cattctcagc ccagtctagt
   148501 tagacagggc aatcaaccga caactccttt ccaaaaggaa aatcctggtg aatttgtcaa
   148561 atatagccaa aaattgaccc agtctcatta tatcttggcg gaagaagttc attctatccc
   148621 taccaagaat gaagaagtgt cagcacctgc tccaaagaaa aacaattatg attttctaaa
   148681 gaagagccaa atctacaata aaaaaagtaa acaaacagaa caagaacgtc gggttgccca
   148741 agagttgaat ctgaccagaa tgacagaata ggggagaaaa catgtcaaag acatatcatt
   148801 ttatcggaat taagggatca gggatgagtg ccttggcctt gatgttgcac cagatggggc
   148861 acaaggttca gggatcagat gttgaaaagt actactttac ccaacgcggt cttgagcagg
   148921 caggaattac cattcttcct tttgatgaaa agaatctaga cggtgatatg gaaattatcg
   148981 ctggaaatgc ctttcgtcca gataacaacg tcgaaattgc ctatgcggac caaaatggta
   149041 tcagctacaa acgttaccat gagtttctag gtagctttat gcgtgacttt gttagcatgg
   149101 gagtagcagg agcacatgga aaaacttcaa cgacaggtat gttgtctcat gtcttgtctc
   149161 acattacaga taccagcttc ttgattggag atgggacagg tcgtggttcg gctaatgcca
   149221 aatattttgt ctttgaatct gacgaatatg agcgtcactt catgccttac cacccagaat
   149281 actctattat caccaacatt gactttgacc atccagatta tttcacaagt ctcgaggatg
   149341 ttttcaatgc ctttaacgac tatgccaaac aaattaccaa gggtcttttt gtctatggtg
   149401 aagatgctga attgcgtaag attacgtctg atgcaccaat ttattattat ggttttgaag
   149461 ctgaaggcaa tgactttgta gctagtgatc ttcttcgttc aacaactggt tcaaccttca
   149521 ccgttcattt ccgtggacaa aacttggggc aattccacat tccaaccttt ggtcgtcaca
   149581 atatcatgaa tgcgacagcc gttattggtc ttctttacac agcaggattt gatttgaact
   149641 tggtgcgtga gcacttgaaa acatttgccg gtgttaaacg tcgtttcact gagaaaattg
   149701 tcaatgatac agtgattatt gatgactttg cccatcatcc aacagaaatt attgcgacct
   149761 tggatgcggc tcgtcagaaa tacccaagca aggaaattgt agcagtcttt caaccgcata
   149821 cctttacaag aaccattgcc ctgttggacg actttgccca tgctttaaac caagcagatg
   149881 ctgtttatct agcgcaaatt tatggctcgg ctcgtgaagt agatcatggt gacgttaagg
   149941 tagaagacct agccaataaa atcaacaaaa aacaccaagt gattactgtt gaaaatgttt
   150001 ctccactcct agaccatgac aatgctgttt acgtctttat gggagcagga gacatccaaa
   150061 cctatgaata ctcatttgag cgtctcttgt ctaacttgac aagcaatgtt caataggatg
   150121 ttcccatgga aattccaatt aagatcattc aggcaagcaa gtttgatttg cctgagatag
   150181 gggcacttca gacctcgtct tttccagctg aaaagcagca actttcccat attttagaag
   150241 aaagtatccg taagtgtgcg gatacctttc ttctagctag ggatgaaaat caacttttag
   150301 gctatatttt atcaagtccc cagtcagaca atccgcaatg tctaaaagta cattctttag
   150361 tcatcgagtc tgaccatcag agacagggcc tgggaacact tcttcttgca gccttgaaag
   150421 aggtggcagt tgagctggat tacaaaggga ttcgtttgga gagtcctgat gagctgcttt
   150481 cctattttga aatgaacggt tttgttgatg aagaagaaat tttgctctat gcaactagcc
   150541 agggctatag tatgatttgg tttaatccct tttatctgga ggaacaatga aaatcagaca
   150601 agcaagatta gaagatttgg atcggattgt tgaacttgaa tttgaaaatt tttcggtcga
   150661 agaagccatt cctccttctg tctttgaagc acatttgaga gaaattcaga cctcttttct
   150721 ggttgctgaa aaagaaggaa gaatcatggg ttatatcgaa ggaccagttg gcctgcaccg
   150781 ccatctgcaa gaccagtctt ttacagaaga aataaaagac tatagtcatg agcctggtgg
   150841 ttatatctct gtgacctgtc tgtctattgc caaggaggca cagggactcg gactgggtca
   150901 gaaattgctg acagccttga aagaagttgc tcttgaagat gagagagatg gcattaatct
   150961 aacctgtcat gactatctca tcgcctatta tgaaaaacat ggatttgtca acgaaggcca
   151021 gtcccagtca acctttgcag gggaaacatg gtatgatatg gtctgggaaa tgaaaaaata
   151081 agttaggaaa agtatcatag attgcttttt ttggactttt aagatataat attatggatt
   151141 atcaacaagg aggaaaaact tttgagtgaa aagtcaagag aagaagagaa attaagcttt
   151201 aaagagcaga ttctgagaga tttagaaaaa gtaaaaggct atgatgaagt tctgaaagaa
   151261 gatgaggcag tagttcgcac tcctgcaaat gaaccttcag ctgaagaact catggctgat
   151321 tccttgtcaa cggtagagga gattatgaga aaagctccta ccgtgcctac tcacccaagt
   151381 caaggtgtac cagcttctcc agcagatgag attcaaagag aaactcctgg tgttccaagt
   151441 catccaagtc aagatgtacc ttcttctcca gcggaagaaa gtggatcaag accaggtcca
   151501 ggtcctgtta gacctaagaa acttgaaaga gaatacaatg aaaccccaac aagggtagct
   151561 gtttcctata cgacggcaga gaaaaaagca gaacaagcag gtccagaaac acctacgcct
   151621 gctacagaaa cagtggatat catcagagat acatcacgtc gtagccgtag agaaggagca
   151681 aaacccgtta agcctaagaa agagaagaag tcacatgtga aagcttttgt gatttcattc
   151741 cttgtattcc ttgccttgct ctcagcaggt ggttactttg gttaccagta cgtgctagat
   151801 tccttattac ctatcgatgc taattctaag aaatatgtga cggttggaat tccagaaggt
   151861 tcaaacgttc aagaaatcgg tacgacgctt gaaaaagctg gtttggtaaa gcatggtctg
   151921 atttttagtt tttatgccaa gtataaaaat tataccgact tgaaagcagg ttactacaat
   151981 ttgcaaaaga gtatgagtac agaagactta ctcaaagagt tgcaaaaagg tggaacagat
   152041 gaaccgcaag aacctgtact tgcgactttg acaattccag aaggttatac cttggatcag
   152101 attgctcaaa ctgtgggtca attgcaaggt gacttcaaag agtctttgac agcggaggct
   152161 ttcttggcta aagttcaaga tgagacgttt atcagtcaag cagtagcgaa atatcctact
   152221 ttactggaaa gtttgcctgt aaaagacagc ggtgcgcgtt atcgtttgga aggatacctt
   152281 ttcccagcta catactctat caaggaaagc acaactattg agagcttgat tgatgagatg
   152341 ttagctgcta tggataagaa cctatctcct tactatagta ctatcaaatc taaaaacttg
   152401 actgtcaatg agttgttgac cattgcttcc ttggtcgaaa aagaaggtgc caagacagaa
   152461 gatcgtaagc tcattgcagg tgtattctac aatcgtttga atcgtgatat gccacttcaa
   152521 agtaatattg caatcttgta tgcccaagga aaactggggc aaaatatcag tctagctgag
   152581 gatgttgcga ttgataccaa cattgattca ccttataatg tttataaaaa tgtaggtctc
   152641 atgcctggtc cagtcgatag tccaagtctg gatgcgattg agtcaagcat caatcaaact
   152701 aagagcgata acctctactt tgtagcagat gtcacagaag gcaaggtcta ctatgctaac
   152761 aatcaagaag accacgaccg caatgtcgct gaacatgtca acagcaaatt aaactaaaca
   152821 aactaaaatt atgtgatact tcacataatt ttctttagaa aatattatca gaagaaagtt
   152881 gagaaaaatg gcagaaaaaa catatcctat gacccttgag gaaaaggaaa aacttgaaaa
   152941 agaattagaa gaattgaaat tggttcgtcg accagaagtg gtagaacgca ttaagattgc
   153001 ccgttcatac ggtgaccttt cagaaaacag tgagtacgaa gcagctaagg atgaacaagc
   153061 ctttgtcgaa ggacaaatct ctagcttaga aacaaaaatc cgctatgctg aaatcgtcaa
   153121 tagcgacgca gttgcccagg acgaagtagc gattggtaaa acagtcacca tccaagaaat
   153181 tggtgaggac gaagaagaag tttatattat cgtaggttca gctggtgcgg atgcctttgc
   153241 aggtaaggtt tcaaatgaaa gcccaattgg gcaggccttg attggcaaga aaacaggtga
   153301 tacagcaacc attgaaacgc ctgttggtag ctatgatgta aaaatcttga aggttgaaaa
   153361 aacagcctaa aaacagaaaa aggagtgggg aggcgatgtg cttcactcac tcctttttcc
   153421 attttgctac tcttcgaaaa tctcttcaaa ccacgtcagc gtcgccttgc cgtatgtatg
   153481 gttactgact tcgtcagttt catctacaac ctcaaaacag tgttttgagc aacctgcggc
   153541 tagtttccta gtttgctctt tgatttttat tgagtattag atgtatagtg cattgaagtt
   153601 aaaatagtac actttgattt ctaagacatt gttagaaatt agattaaatt ccttaatcga
   153661 tttgcgcatg ttttatttca tttcactata ctttagattg gaaaataagg aatcacataa
   153721 atcgcaagaa atagggaatc tgattcgtgt ttataaccgt tcaaaaagag aagaggctga
   153781 aagtgagcca cttaatcttt atgtcgaaga tgaaaagggc aatctcctgg caggtttgat
   153841 agcagagact tttggaaatt ggctagaaat cgagtatttg tttgtaaaag aggaactgcg
   153901 agggcaagga atcggttcaa aactattgca acaggcagaa agtgaagcta agaatcgaaa
   153961 ttgttgtttt gcctttgtca atacttacca gttccaggca ccggactttt atcagaaaca
   154021 tggctacaag gaagtttttt ctttgcaaga ctatctctac attaggcaaa gatattatta
   154081 ccaaaagaat ctgtaaggtg agtatggagg tataatacaa agagaggctc gcacataagt
   154141 atggaggtgg actgatgtat atgagtaact attgataaat accagttata acctagaaat
   154201 tgtgtctttc tagacgatat tgaggacaat ataatcgtag ccccaaaatt aggaatcaag
   154261 acttatcagg ttaagaaaag aagtgatgtt gttgatattt taaacaattt atttaaacta
   154321 aaaactctct atctattaat ccgagattcc cctctcggat tttgtgttgc tttcattaaa
   154381 tttacaggta agacttgcta gcttcagtaa atatacacaa gtttttcaga atagagtgaa
   154441 atccaaaaga aaatggaaat aatgaaagct cttgtaggca taagaaaaca cctctgtgtt
   154501 atacttgttg ttcaaccaca aacacaagaa aggcacagaa atgcaagaca attatactac
   154561 aaaaggtaaa catttgacaa tcgatagccg tcgcttaatc gaaagatgga aaaaagaagg
   154621 aaaatcaaat agagaaattg cctctctact tggaaaagct cctcaaacta tccacactaa
   154681 aatcaagcgt aggacagtcc gaaaatgtct tggaaaaggg cgcttcaaag aggtttattc
   154741 tgccgactat gctcaacagt cttatgaaaa taatcgcaag cactcggtca agagatcaag
   154801 cgtgaccaag gaactaaagg aaaagattct ccactatcat aaccaaaaat ttttgcctga
   154861 aatgatggtt atggctaaag gggttaacgt gggaatttca accatttact attggattca
   154921 tcatggaaaa ttggggtaaa gcaagcagga tctgctttac cctagaaaag gaaaagcgct
   154981 taagaaacag gccagca
//
LOCUS       DAVHLA010000002        89392 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVHLA010000002 DAVHLA010000000
VERSION     DAVHLA010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 89392)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 89392)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..89392
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.002"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(<1..402)
                     /locus_tag="VVO77_000155"
     CDS             complement(<1..402)
                     /locus_tag="VVO77_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU5692240.1"
                     /translation="MTIRFEEKVSIENAQLVCQWSNSLGKVFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQEQGLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQM"
     gene            472..1131
                     /locus_tag="VVO77_000156"
     CDS             472..1131
                     /locus_tag="VVO77_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEU5692241.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACVIIFGKLLL
                     V"
     gene            complement(1183..2334)
                     /locus_tag="VVO77_000157"
     CDS             complement(1183..2334)
                     /locus_tag="VVO77_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEU5692242.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYTREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGNRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(2349..2903)
                     /locus_tag="VVO77_000158"
     CDS             complement(2349..2903)
                     /locus_tag="VVO77_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692243.1"
                     /translation="MFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFPL
                     VQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNSN
                     IEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDIP
                     NFSELSETEDFEIIPRIEKQEGQK"
     gene            complement(2940..3080)
                     /locus_tag="VVO77_000159"
     CDS             complement(2940..3080)
                     /locus_tag="VVO77_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692244.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WT"
     gene            3309..3410
                     /locus_tag="VVO77_000160"
                     /pseudo
     CDS             3309..3410
                     /locus_tag="VVO77_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            complement(3382..4158)
                     /locus_tag="VVO77_000161"
     CDS             complement(3382..4158)
                     /locus_tag="VVO77_000161"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEU5692245.1"
                     /translation="MPKTLTKKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIKQAVAYQK"
     gene            complement(4151..5374)
                     /gene="trpB"
                     /locus_tag="VVO77_000162"
     CDS             complement(4151..5374)
                     /gene="trpB"
                     /locus_tag="VVO77_000162"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEU5692246.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            complement(5352..5951)
                     /locus_tag="VVO77_000163"
     CDS             complement(5352..5951)
                     /locus_tag="VVO77_000163"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEU5692247.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVAADLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQSFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            complement(5938..6705)
                     /gene="trpC"
                     /locus_tag="VVO77_000164"
     CDS             complement(5938..6705)
                     /gene="trpC"
                     /locus_tag="VVO77_000164"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEU5692248.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDC
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNTGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            complement(6702..7706)
                     /gene="trpD"
                     /locus_tag="VVO77_000165"
     CDS             complement(6702..7706)
                     /gene="trpD"
                     /locus_tag="VVO77_000165"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEU5692249.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEDYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            complement(7717..8283)
                     /locus_tag="VVO77_000166"
     CDS             complement(7717..8283)
                     /locus_tag="VVO77_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEU5692250.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMICDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            complement(8280..9641)
                     /gene="trpE"
                     /locus_tag="VVO77_000167"
     CDS             complement(8280..9641)
                     /gene="trpE"
                     /locus_tag="VVO77_000167"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEU5692251.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQAIDRDPLDFLYEVTHKSQHHSDLPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMEVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRSVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            complement(10142..10219)
                     /locus_tag="VVO77_000168"
                     /pseudo
     CDS             complement(10142..10219)
                     /locus_tag="VVO77_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(10824..11825)
                     /locus_tag="VVO77_000169"
     CDS             complement(10824..11825)
                     /locus_tag="VVO77_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU5692252.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            complement(11933..12301)
                     /locus_tag="VVO77_000170"
     CDS             complement(11933..12301)
                     /locus_tag="VVO77_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692253.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKCYIDRLLYVFINPTHFTEKVNLQFYGSFFSYEFICREVGN
                     ILKNKGVKCNLNFFEGEEYL"
     gene            complement(12397..13107)
                     /locus_tag="VVO77_000171"
     CDS             complement(12397..13107)
                     /locus_tag="VVO77_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEU5692254.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            complement(13110..14801)
                     /locus_tag="VVO77_000172"
     CDS             complement(13110..14801)
                     /locus_tag="VVO77_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU5692255.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            complement(14813..15823)
                     /locus_tag="VVO77_000173"
     CDS             complement(14813..15823)
                     /locus_tag="VVO77_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5692256.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            complement(15927..16994)
                     /locus_tag="VVO77_000174"
     CDS             complement(15927..16994)
                     /locus_tag="VVO77_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU5692257.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            complement(17019..17678)
                     /locus_tag="VVO77_000175"
     CDS             complement(17019..17678)
                     /locus_tag="VVO77_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEU5692258.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            complement(17858..18868)
                     /gene="galE"
                     /locus_tag="VVO77_000176"
     CDS             complement(17858..18868)
                     /gene="galE"
                     /locus_tag="VVO77_000176"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU5692259.1"
                     /translation="MAILVTGGAGYIGSHTVVELLNLGKEVIIVDNLSNSSILVLDRI
                     EAITGIRPVFYELDVCDKPALRKVFEQESIDAAIHFAGYKAVGESVQKPVMYYKNNIM
                     STLALVEVMSEFNVKKIVFSSSATVYGINNQSPLIETMQTSATNPYGYTKVMLEQILK
                     DVHVADSEWSIALLRYFNPIGAHESGLIGEDPSGIPNNLMPYIAQVAVGKLSELSVFG
                     NDYDTLDGTGVRDYIHVVDLAIGHIKALEKVSEKTDVYIYNLGSGEGTSVLQLVNTFE
                     SVNKIPIPYKIVPRRSGDVATCYANADKAYKELNWRTTKSIEDMCRDTWNWQSKNPNG
                     YN"
     gene            complement(18881..20356)
                     /gene="galT"
                     /locus_tag="VVO77_000177"
     CDS             complement(18881..20356)
                     /gene="galT"
                     /locus_tag="VVO77_000177"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEU5692260.1"
                     /translation="MKTIIDNFVDRVIEYGMYNEIDKIYVKNRVLALIGEEGTDRISD
                     ENDLKQIKDYLVEIALKNGKIKDLIEEKECLGAELMNFIVPLPSRLNDIFWSSYDISP
                     QEAVEEFYKLSKDSDYIKTSAIAKNIEFRASTKYGELEITINLSKPEKDPKTIAAEKL
                     VKATNYPKCLLCMENEGYQGRINYPARSNHRIIRLKLGDEVWGFQYSPYLYFNEHAIF
                     LNSQHVPMAITSKTFEQLLEIVDILPGYFAGSNSDLPISGGSILSHNHYQGGKHIFPM
                     EKAKFESEFRFKDFEDVNAGIVKWPMSVIRLQSENKNRLLDLATKILNKWREYSDLEV
                     DIIAMTEDVPHHTVTPIARKVDGRYELDIVLRDNHTTEQYPDGVFHPHQDVQHIKKEN
                     IGLIEVMGLAILPPRLKPELEEVGKYLLGEDNAIADYHLEWADQLKEKYPRINKEEVN
                     SVVQHEAGQVFARVLEDAGVYKNTPSGHEAFMRFVKSVGIN"
     gene            complement(20369..21010)
                     /locus_tag="VVO77_000178"
     CDS             complement(20369..21010)
                     /locus_tag="VVO77_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate uptake regulator PhoU"
                     /protein_id="HEU5692261.1"
                     /translation="MLRLYLENEIIELSNNLETIWVSVLDKYEKLFEYLSNEERIELI
                     KEDLIINESVLNVDKKGYELICLQHPVSYDLRRIISVIKISTDIERIGDRIVEILKNL
                     QIIQNNEILKKIISEIKILHEVIGLHMNRAISCYREEQSGCLDMVVIQKQNEIEELST
                     NIEKKIMNYIFEDDGNVSEVIGALDIIHHLDKIAHTTQSIYKWIMYRKYGNIN"
     gene            complement(21068..21280)
                     /locus_tag="VVO77_000179"
     CDS             complement(21068..21280)
                     /locus_tag="VVO77_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692262.1"
                     /translation="MDERFLDHAIINQIDVTSEQIVLMSDGFYEFYQNNQNKTFEELI
                     KMRFNSSAIDPIYGKKDDASIVVIDV"
     gene            complement(21623..21919)
                     /locus_tag="VVO77_000180"
     CDS             complement(21623..21919)
                     /locus_tag="VVO77_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692263.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYNKMK"
     gene            complement(21903..24062)
                     /gene="pfbA"
                     /locus_tag="VVO77_000181"
     CDS             complement(21903..24062)
                     /gene="pfbA"
                     /locus_tag="VVO77_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HEU5692264.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(24312..24572)
                     /locus_tag="VVO77_000182"
     CDS             complement(24312..24572)
                     /locus_tag="VVO77_000182"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692265.1"
                     /translation="MSDIKVNIPGECLYDKVFVLSFIIYNISINLNIVNGIFYIQAKK
                     DSITFEWKAKEQTRKLAIDSSKPCFEVVDIVKGNKNRTNRSG"
     gene            complement(25193..26419)
                     /locus_tag="VVO77_000183"
     CDS             complement(25193..26419)
                     /locus_tag="VVO77_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEU5692266.1"
                     /translation="MPNYNIPFSPPDITEAEITEVVDTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSIYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAASRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(26462..27154)
                     /locus_tag="VVO77_000184"
     CDS             complement(26462..27154)
                     /locus_tag="VVO77_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEU5692267.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            complement(27327..29078)
                     /locus_tag="VVO77_000185"
     CDS             complement(27327..29078)
                     /locus_tag="VVO77_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5692268.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYGLLTFLALSFLLATMVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGFSIG
                     ITVGTMYAFIQYINRLFDPLIEVTQNFSTLQTAMVSAGRVFALIDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQETSDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLALGV
                     TYHKMYSLQAGAMADTL"
     gene            complement(29068..30813)
                     /locus_tag="VVO77_000186"
     CDS             complement(29068..30813)
                     /locus_tag="VVO77_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5692269.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYTTSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLLAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGTI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGTHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(31019..31315)
                     /locus_tag="VVO77_000187"
     CDS             complement(31019..31315)
                     /locus_tag="VVO77_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEU5692270.1"
                     /translation="MSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            complement(31468..31925)
                     /locus_tag="VVO77_000188"
                     /pseudo
     CDS             complement(31468..31925)
                     /locus_tag="VVO77_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            32059..32886
                     /gene="xth"
                     /locus_tag="VVO77_000189"
     CDS             32059..32886
                     /gene="xth"
                     /locus_tag="VVO77_000189"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEU5692271.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTVTFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            32898..33035
                     /locus_tag="VVO77_000190"
     CDS             32898..33035
                     /locus_tag="VVO77_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEU5692272.1"
                     /translation="MDYNAVIPELLVSNIEQSRSFYCGLLGFRIEYQRPEENFLLKSV
                     N"
     gene            33146..33274
                     /locus_tag="VVO77_000191"
     CDS             33146..33274
                     /locus_tag="VVO77_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HEU5692273.1"
                     /translation="MKANYPIYRPLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     regulatory      33657..33752
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            34152..34733
                     /locus_tag="VVO77_000192"
     CDS             34152..34733
                     /locus_tag="VVO77_000192"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEU5692274.1"
                     /translation="MKLLEDRILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAAAGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            34733..35995
                     /locus_tag="VVO77_000193"
     CDS             34733..35995
                     /locus_tag="VVO77_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEU5692275.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPLDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTRFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(36046..36507)
                     /locus_tag="VVO77_000194"
     CDS             complement(36046..36507)
                     /locus_tag="VVO77_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein DpnD"
                     /protein_id="HEU5692276.1"
                     /translation="MKTKQLVASEEVYDFLKVIWPDYETESRYDNLSLIVCTLSDPDC
                     VRWLSENMKFGDEKQLALMKEKYGWEVGDKLPEWLHSSYHRLLLIGELLESNLKLKKY
                     TVEITETLSRLVSIEAENPDEAERLVREKYKSCEIVLDADDFQDYDTSIYE"
     gene            complement(36504..37268)
                     /locus_tag="VVO77_000195"
     CDS             complement(36504..37268)
                     /locus_tag="VVO77_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-2 restriction enzyme DpnI"
                     /protein_id="HEU5692277.1"
                     /translation="MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNH
                     FENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYT
                     KNFEVNNFLVLPKQFVTPKSIIQRKPLAPTARRAGWIGCNIDLSQVPSKGRIFLVQDG
                     QVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKN
                     IFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL"
     gene            complement(37449..37853)
                     /locus_tag="VVO77_000196"
     CDS             complement(37449..37853)
                     /locus_tag="VVO77_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEU5692278.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVSI"
     gene            complement(37923..39404)
                     /locus_tag="VVO77_000197"
     CDS             complement(37923..39404)
                     /locus_tag="VVO77_000197"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEU5692279.1"
                     /translation="MILVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLEMIEDSQTAREILGTELMDLVTPYPSQVNRDFWEAYVHSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFARVLEDAGVYKQTEQGQTAFMRFVEHVGILLD"
     gene            complement(39423..40601)
                     /locus_tag="VVO77_000198"
     CDS             complement(39423..40601)
                     /locus_tag="VVO77_000198"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEU5692280.1"
                     /translation="MAQHLTTEVLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLDRLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            40766..41773
                     /gene="galR"
                     /locus_tag="VVO77_000199"
     CDS             40766..41773
                     /gene="galR"
                     /locus_tag="VVO77_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEU5692281.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFKNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(41819..42856)
                     /locus_tag="VVO77_000200"
     CDS             complement(41819..42856)
                     /locus_tag="VVO77_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEU5692282.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(42857..43210)
                     /locus_tag="VVO77_000201"
     CDS             complement(42857..43210)
                     /locus_tag="VVO77_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEU5692283.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(43454..44344)
                     /locus_tag="VVO77_000202"
     CDS             complement(43454..44344)
                     /locus_tag="VVO77_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEU5692284.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            44477..45013
                     /locus_tag="VVO77_000203"
     CDS             44477..45013
                     /locus_tag="VVO77_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEU5692285.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNLPTSYLQHLVMSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(45179..45985)
                     /locus_tag="VVO77_000204"
     CDS             complement(45179..45985)
                     /locus_tag="VVO77_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEU5692286.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(46330..47850)
                     /locus_tag="VVO77_000205"
     CDS             complement(46330..47850)
                     /locus_tag="VVO77_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEU5692287.1"
                     /translation="MTNLIATFQDRFGDWLTALSQHLQLSLLTLLLAILLAIPLAVYL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLNGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITENQMSQLNYQVGVEGKSAEQVAKEFLQEQGLLKK"
     gene            complement(47843..48571)
                     /locus_tag="VVO77_000206"
     CDS             complement(47843..48571)
                     /locus_tag="VVO77_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5692288.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVEENIALIPEM
                     KGWTKEEIAQKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKILLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVS
                     NPETILKAPATDFVADLFGGSIHD"
     gene            complement(48586..49350)
                     /locus_tag="VVO77_000207"
     CDS             complement(48586..49350)
                     /locus_tag="VVO77_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HEU5692289.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(49354..49797)
                     /locus_tag="VVO77_000208"
     CDS             complement(49354..49797)
                     /locus_tag="VVO77_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU5692290.1"
                     /translation="MKDGHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(50479..50775)
                     /locus_tag="VVO77_000209"
     CDS             complement(50479..50775)
                     /locus_tag="VVO77_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEU5692291.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETAKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            complement(50797..51861)
                     /gene="pepA"
                     /locus_tag="VVO77_000210"
     CDS             complement(50797..51861)
                     /gene="pepA"
                     /locus_tag="VVO77_000210"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEU5692292.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPYVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            52262..52963
                     /locus_tag="VVO77_000211"
     CDS             52262..52963
                     /locus_tag="VVO77_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="HEU5692293.1"
                     /translation="MTKTILVTGGTSYISSHTVKALLNAGYQVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNAAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            53386..54345
                     /locus_tag="VVO77_000212"
     CDS             53386..54345
                     /locus_tag="VVO77_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5692294.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            54335..55291
                     /locus_tag="VVO77_000213"
     CDS             54335..55291
                     /locus_tag="VVO77_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEU5692295.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSFFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRSRQ"
     gene            55288..56040
                     /locus_tag="VVO77_000214"
     CDS             55288..56040
                     /locus_tag="VVO77_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU5692296.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINNKKICIYS"
     gene            56136..57101
                     /locus_tag="VVO77_000215"
     CDS             56136..57101
                     /locus_tag="VVO77_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU5692297.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(57326..57568)
                     /gene="yidD"
                     /locus_tag="VVO77_000216"
     CDS             complement(57326..57568)
                     /gene="yidD"
                     /locus_tag="VVO77_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEU5692298.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDRFSLKRNQEGE"
     gene            complement(57568..58290)
                     /locus_tag="VVO77_000217"
     CDS             complement(57568..58290)
                     /locus_tag="VVO77_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEU5692299.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVVNKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            complement(58277..58846)
                     /locus_tag="VVO77_000218"
     CDS             complement(58277..58846)
                     /locus_tag="VVO77_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEU5692300.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            complement(58865..59593)
                     /locus_tag="VVO77_000219"
     CDS             complement(58865..59593)
                     /locus_tag="VVO77_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEU5692301.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            complement(59593..60333)
                     /gene="xerD"
                     /locus_tag="VVO77_000220"
     CDS             complement(59593..60333)
                     /gene="xerD"
                     /locus_tag="VVO77_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEU5692302.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            complement(60324..60785)
                     /locus_tag="VVO77_000221"
     CDS             complement(60324..60785)
                     /locus_tag="VVO77_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU5692303.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            complement(60782..61303)
                     /locus_tag="VVO77_000222"
     CDS             complement(60782..61303)
                     /locus_tag="VVO77_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEU5692304.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWMEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            complement(61279..62250)
                     /locus_tag="VVO77_000223"
     CDS             complement(61279..62250)
                     /locus_tag="VVO77_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEU5692305.1"
                     /translation="MTNKIYEYKDDRDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            complement(62247..63041)
                     /gene="racE"
                     /locus_tag="VVO77_000224"
     CDS             complement(62247..63041)
                     /gene="racE"
                     /locus_tag="VVO77_000224"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEU5692306.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            complement(63248..63496)
                     /locus_tag="VVO77_000225"
     CDS             complement(63248..63496)
                     /locus_tag="VVO77_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEU5692307.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            complement(63752..65377)
                     /gene="treC"
                     /locus_tag="VVO77_000226"
     CDS             complement(63752..65377)
                     /gene="treC"
                     /locus_tag="VVO77_000226"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEU5692308.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMTDYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDTSENAGFSTGTPWLKVGKSYKDINVENEIKGLIFTFY
                     QDLIRLRKEMPIISEGNYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            complement(65555..67522)
                     /gene="treP"
                     /locus_tag="VVO77_000227"
     CDS             complement(65555..67522)
                     /gene="treP"
                     /locus_tag="VVO77_000227"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEU5692309.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATNPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            67707..68417
                     /gene="treR"
                     /locus_tag="VVO77_000228"
     CDS             67707..68417
                     /gene="treR"
                     /locus_tag="VVO77_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEU5692310.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            complement(68450..69253)
                     /locus_tag="VVO77_000229"
     CDS             complement(68450..69253)
                     /locus_tag="VVO77_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU5692311.1"
                     /translation="MTSLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFISVIGGN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKNLSVRKRAKDIARVFQDPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMTDLMKPKLLLLDEHTAALDPKTSQMVMNLTQKIVEHHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(69266..70159)
                     /locus_tag="VVO77_000230"
     CDS             complement(69266..70159)
                     /locus_tag="VVO77_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5692312.1"
                     /translation="MNFVLSSLSEGLLWSIVAIGVYLTFRILDIADMTAEGAFPLGAA
                     VVVSQIQAGANPWLATLLALLAGMVAGLVSGMLHTKMKIPALLTGIVTLTGLYSINIK
                     IMGSVPNLSLGDSATVFKQLASLGLTNEGTVFSLSLACFLLVCLVLTLLMKTEIGLVL
                     RSTGDNIPMSEANGVNVDTMKIVGYMISNGLIALCGSLFAQNDGFSDVTSGTGTIVVG
                     LSSVIIAEVLIHDLTIGGRLLSIGIGAIVYRLIILNIYEIPNLDQNLVRLFNAILLAL
                     VLFAPELQKRLKIRGLKLRNE"
     gene            complement(70171..71031)
                     /locus_tag="VVO77_000231"
     CDS             complement(70171..71031)
                     /locus_tag="VVO77_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU5692313.1"
                     /translation="MSQFITHQSLYATREGFVDKLAKQGYVEGENIEIDLQNAQGEQR
                     NLKTISQQLAESSDVVLAIARPSAQSLANTTQTTPVIFSAVTDPVSAKLVESREHPGG
                     NVTGTSDQSSDAISTQINLIKKVLPKAKTIGILYTQSEPNSVVQKDEAKRLLKEKGFT
                     VVEKTILDSNNVKAAAESLMAEVDMVFVPTDNIISLTMETVKQVSIKHKVPVFGGSTE
                     MIAVGGLYNYGTNYEELGRQTARMLIRVLKGEKPENIAVELPEKLELHTNQEMADALG
                     IDISKLEGKE"
     gene            complement(71598..72524)
                     /locus_tag="VVO77_000232"
     CDS             complement(71598..72524)
                     /locus_tag="VVO77_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5692314.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            complement(72535..73602)
                     /locus_tag="VVO77_000233"
     CDS             complement(72535..73602)
                     /locus_tag="VVO77_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5692315.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            complement(73611..74537)
                     /locus_tag="VVO77_000234"
     CDS             complement(73611..74537)
                     /locus_tag="VVO77_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5692316.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            complement(74537..76033)
                     /locus_tag="VVO77_000235"
     CDS             complement(74537..76033)
                     /locus_tag="VVO77_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5692317.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGALTFLLALPTIALVY
                     IVRLIGSSISLPDSFPILGAGDWRSYVLPAVILGLLGAPGTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            complement(76100..78079)
                     /locus_tag="VVO77_000236"
     CDS             complement(76100..78079)
                     /locus_tag="VVO77_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU5692318.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KAVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            complement(78765..79958)
                     /locus_tag="VVO77_000237"
     CDS             complement(78765..79958)
                     /locus_tag="VVO77_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEU5692319.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            complement(80096..81538)
                     /gene="gtfA"
                     /locus_tag="VVO77_000238"
     CDS             complement(80096..81538)
                     /gene="gtfA"
                     /locus_tag="VVO77_000238"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HEU5692320.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKALFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTMLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVVEIDLQNQTYRVIENGVEVSF"
     gene            complement(81838..82671)
                     /locus_tag="VVO77_000239"
     CDS             complement(81838..82671)
                     /locus_tag="VVO77_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU5692321.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            complement(82685..83551)
                     /locus_tag="VVO77_000240"
     CDS             complement(82685..83551)
                     /locus_tag="VVO77_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU5692322.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAAFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSMVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFLLIVVIS
                     IIQLRVSKKFEI"
     gene            complement(83565..84824)
                     /locus_tag="VVO77_000241"
     CDS             complement(83565..84824)
                     /locus_tag="VVO77_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU5692323.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            complement(84916..87078)
                     /locus_tag="VVO77_000242"
     CDS             complement(84916..87078)
                     /locus_tag="VVO77_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEU5692324.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHITLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            87186..88046
                     /locus_tag="VVO77_000243"
     CDS             87186..88046
                     /locus_tag="VVO77_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEU5692325.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIS
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQSPSHTRKEYS
                     QYQLVRKATL"
     gene            88043..88978
                     /locus_tag="VVO77_000244"
     CDS             88043..88978
                     /locus_tag="VVO77_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEU5692326.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEINSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(89104..89191)
                     /locus_tag="VVO77_000245"
     tRNA            complement(89104..89191)
                     /locus_tag="VVO77_000245"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(89155..89157),aa:Ser,seq:gct)
     gene            complement(89198..89271)
                     /locus_tag="VVO77_000246"
     tRNA            complement(89198..89271)
                     /locus_tag="VVO77_000246"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(89235..89237),aa:Ile,seq:gat)
     gene            complement(89307..89377)
                     /locus_tag="VVO77_000247"
     tRNA            complement(89307..89377)
                     /locus_tag="VVO77_000247"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(89343..89345),aa:Gly,seq:tcc)
BASE COUNT        26812 a        19764 c        15835 g        26981 t
ORIGIN      
        1 catttgaacg atttcaaatc cttctttttg gtaaagattc tgagctcttt gatttgcctc
       61 gaagacattt agagaaatac tatctatatc ttcattttca aaggccaaac taacaaattt
      121 ccttaaagcc tggctaccta agccttgctc ctgtttctgg gggttgataa aaaatctccc
      181 gatatgaaga ttgctgtctt ctagcctgat tttctggata agtcccacaa actcttgttc
      241 atcaaagatt gaaaagactc cttccaaggc ttgaagggtc agtagaaaag gaatccttgg
      301 tcccatccat tgttcttgaa agactttgcc taaggagttg gaccattggc atacgagctg
      361 agcgttttct atactcacct tttcttcaaa acgaattgtc atcttttcct caccatctta
      421 tctatgtttc tccattatac tatttctccc attttttacg aatagataag tatgattgat
      481 ttttattttt ttctcgtcgg gagcattctc gcttcctttc ttggtttggt cattgaccgt
      541 tttccagagc aatccattat cagttcagcc agtcactgcg attcctgtca gactcgcttg
      601 cgtcccttag atttgattcc gattctctca caggtcttca atcgctttcg ctgtcgctac
      661 tgcaaagttc gctatcctgt ctggtatgcc ctctttgaat tagtcttagg actcctcttt
      721 ctgctttact cttgggaatt gctttccttg gggcaagtcg tcctaatcac cgctggtttg
      781 accttaggca tctacgactt tcgccatcag gaatatccct tactggtctg gatgactttc
      841 cacctaatcc taatagcttc ctctggctgg aatctggtca tggtctcctt ccttgctctt
      901 ggaattttgg ctcattttat cgatatccgc atgggcgcag gagatttcct ctttttagct
      961 tcttgtgctc tcgtctttag cgtaacggag ttactgatct tgattcagtt cgcttctgcg
     1021 acgggtattc tggcctttct cctgcaaaag aaaaaggaaa gacttccttt cgtgcctttc
     1081 ctcttacttg ctgcttgtgt gattattttt ggtaagctac tgcttgtctg ataaaatcca
     1141 atttctgcca tatgtccttc atgaaattat ttcacagtta aattataaat tatttctttt
     1201 gtacaaaggg atgatgttat caaatcgatc tgttcttcta tcttcttgat actgatcaaa
     1261 aaatttcatt tcgactgaaa atatttcgct tataaactgt aaacgaatac tttgtttaga
     1321 cattatagtc gctagactga ctagatgatt actcaaaacg acgtccagaa tactctttac
     1381 tttgcttggt tttttaacaa aaatttgatc atccaaaggt tcaatcattt tgtaaccttt
     1441 ttgcgcaatt tgacgataaa agtaagaatg ttgctttgga gtcaataatc ctaacttaaa
     1501 agctcgatac tctaaagcct gtatcgaaac attcaaatcc gacttcaata aaatataact
     1561 atcaggattg ctgacacgct tgccaaccct ctcttcaaat ttgactaaaa actcttcttt
     1621 tggcaataaa aaacatgatg caaaataatt tgcttcttgc tccaaacgat tgccatcttc
     1681 attcatatct ttatatttgt gtaaaagaat atgtcctagc tcatgagcta agtcaaaatt
     1741 tcgacgtaca gatgatttat tcgttcccaa cacaatataa ggtcttccca attttgacca
     1801 tgcgctataa gcatcagctt ggccattaat taatcgttcc acgatataga tgcctgaacg
     1861 ttctaattta taaagcaaat catgattatc ttttgaaata cctaattttt ccctggtata
     1921 aagagccaat tcctcaatgg attctccctt atgataagat tcactcacta cattacttag
     1981 gtcatgaatt gtaatattag gtataattac aaaactttca aaataatcaa tcaaactatc
     2041 taccttatgt aaatacatag tttgaatatc tattgttttc cgtgttgcta ggtctgcatt
     2101 tctaaaggca attacagaag aatcaaatcg aatgctctct tcttcctgtt caaaataagt
     2161 taaatcaaca tgaaattggt tggccaaatg cattttggtt gataatttag gtttcgtttc
     2221 gttggactca aactgccaaa tggcttgttc cgttaaatta attctctgag ctaattctgc
     2281 tctacttaaa ccatttaaca gccgtaattc tttcaatacc cgaccattaa acatttacat
     2341 attccttact acttttgacc ttcttgtttt tctattcttg gaataatttc aaaatcttct
     2401 gtttccgata attctgaaaa attaggaata tcttgatatt tagcttcttc gaaatggtac
     2461 gaacttgatt gaatatactc agacaaatct tgaatcaagt gtaactgacc agttcgtgca
     2521 tcaggcataa caacatctac agatataata ttgttttctg agtccgcctc ataagttaaa
     2581 atcataaatt tttcgatatt cgaattttta gtagcttgtt caatttcttg aatcatttca
     2641 tcagaaacta actccatctg aattggaaag gaatgactat cttcatcatt tttgtaggaa
     2701 gaatgttgat taagataaag tgtattcatc tgagcatatt caaataagta gccactctta
     2761 tttttttgta ccaaaggaaa ttggttcgta agtcgcttct taccctttat aattaacaat
     2821 actttcccat atttttctgt atttgtttca aattctaaat atccccaagt ctgtcctgct
     2881 aattgtaatt tatactcaaa caaatctgct gatgcaaatg cagtatcaat atgattaggt
     2941 cacgtccatg cataaccatt cgacactatc attgtctctc ttttttctag acgttcatct
     3001 acataatctt tttgcccttt catcaaagta tctacaattt tttgtgcctc aagcgaatca
     3061 aagagatcct gattcaacat aattcttcct cctccaaata ctttttaatg aattatatca
     3121 ttttcttaaa gaaattacta caataattag ctttttctta aagttctgtg tcagagtaat
     3181 ttagaaaatt atatcttcta tagtaaaatc aattaaaaac tgaacaaatt tattgggaaa
     3241 ttcaaatcac tttcttaaaa tattttagga accgtagtgt aatattccag attcaattca
     3301 ctataaaact agcctttcgc ctgcaaaaga aaaaggaaag acttcctttc gtgcctttcc
     3361 tcttacttgc tacttgttta attatttttg gtaagctact gcttgtttga taaagtcctg
     3421 aatcggctct ccttggtgga gagcttttac tattttcgaa ccgacgataa caccatctga
     3481 caccgcattg aagcgttcca gatcggcttg actagataca ccaaaacctg tcaagactgg
     3541 gatgtcggcc acttgatgaa gttgcgccaa gtgcttgtcc aaatctgcac ggtaattgcc
     3601 tgatttccct gttaccccat tgatggcaac ggcatagacg aatccctccg ccccttcaat
     3661 caactctttc tggcgctcaa ttcctgtggt caagcttact aaaggaatca aggcgatatc
     3721 tgtatctgcc aaaaatggtt ctacaaagtt ggcatgttca tgaggcaggt ctgggataat
     3781 caagcccttc acagctgtat cagccagatc tttgacaaag ttctccacac cgtactgaaa
     3841 gagggggttg aagtaggtca tgatgaccag tggaatctct gtttcaatgg ttttcaaggt
     3901 ttcaactaaa gcctgggtag aggtcccgtg ggctaaactg cgcaagccag cttcttcgat
     3961 aacaggtcca tctgcaacag ggtctgaaaa gggaataccc acttcaattg cagagacacc
     4021 caaatcttct aaaaagtgaa ttgtttcagc aagaccatcc aaaccttttt cgtggtcacc
     4081 agccatgata tagggaacaa aaattccttt tccagctgct ttaatagcat ttaatttttt
     4141 tgttagtgtc ttaggcatga gcttctccct tctttgctgc atctgcttcc aagcggtctt
     4201 tgacttgaac cacatccttg tccccacgac ctgataggca gacaatcata gacttttctg
     4261 gtccaagttc tttggccaat ttcaccgcaa aggcgatagc atggctagat tccaaggctg
     4321 ggataatccc ttccacacga gacaagagtt ggaatccttc caaggcttct tcgtctgtca
     4381 cagggacata gctggcacgt ttaatatcgt ggtagtgaga atgctctgga ccgataccag
     4441 gatagtccaa acctgctgag atagagaagg cttcaagaat ttgaccatgg gcatcttgga
     4501 gcacatccat gagggaaccg tgaaggacac ctggacgacc cttggtcaag gtagctgcgt
     4561 ggtgctccgt atccacacca agtccagccg cttcagctcc atacatggct actgactcat
     4621 cttctacaaa gggatggaag agaccaatgg cattcgaccc accaccaaca caggctacta
     4681 gggcatctgg cagattttgt cctgtcaagt cacggtactg ttgtttagcc tctcgaccaa
     4741 tgacactttg gaagtcacga acaatttctg gaaatggatg aggccccaag gcagaaccaa
     4801 ggatatagtg ggtatcatct atattagcca cccatgaacg aagagctgca ttgaccgcat
     4861 ccttgagcac gcgcgaacca tctgtcacgg cctcgacctt agctcccaaa agctccatac
     4921 ggaagacatt gagggcttgg cgtttgacat cttcctcacc catgtagatg gtacattcca
     4981 tgttaaagag ggccgcagca gttgcagttg ccacaccgtg ctgaccagca ccagtttctg
     5041 cgataatttt ctttttaccc atgcgtttgg caagccaaac ttgtcccaag gcattgttaa
     5101 tcttgtgggc tcctgtatgg ttaaggtctt cccgtttgag ataaatcttg gctccgccga
     5161 tatgctgggt caagtttttt gcgtaataaa gaggagtttc acgtcctacg tactggcgca
     5221 aaagctggtt taattcctct tggaaacttg ggtctgcctg actttcacgg taggccttct
     5281 ccaactccaa aactgctgtc atcaatgttt ctgggacaaa acgtccgccg aattttccgt
     5341 aaaatccatc tttatttggt tcctgatatg ccatgcttta ccctctctat aaatcttcta
     5401 atcttttcat gatctttttg tccatctgtc tccactccgc tcgatacatc tactgcatag
     5461 ggagtaaaat gttgaattgc ttttactaca ttatcttcat taaggccacc tgcgataaag
     5521 aagggctgtg ctagtccagt cgtatccagt tgaccccaat caaaggactg accacttcct
     5581 gccacagggg catcaaagag tagataatct gcctgagaat tggggacatg cccatttcca
     5641 tctacctgca cagcctgaat actggcacaa ggcaaattct caaataaatc agctgccacc
     5701 tgaccgtgaa cttgaaccaa gtccaagcca actttgtcaa tcgcttccag cagttctacc
     5761 cgacttggtg aaacaaatac tccaaccttt ttcacatctg caggaataag ctttgccaac
     5821 tcagctgcct cttctaaagt cacctgtctt ttactaggtg caaagacaaa accgatatag
     5881 tcggctcctg ctgaaacggc tgtttccacc gcttctttgg tcgatagtcc acaaatttta
     5941 acctttgtca atctgcaact ccttgattct ctgggccaca ttttctgcct gcataagagc
     6001 tgtccctacc aaaattccgt taaagtatgg ggctagtcgt tccgcatcct gccctgtgaa
     6061 aatggcagat tcagaaatgt aatagcgacc ttcctcaaag taaggggcta aatctacact
     6121 ggtctgcaag tcgacctcaa aggtagtcaa gttgcggttg ttgaccccga taatctcagc
     6181 accaagtctg tgggctacct ctagttcagc tagattgtga gtctccacta agacttccag
     6241 accaagctct gtcgcgtagt catacagttc cttgaggcgt tcttcggaca aggctgccac
     6301 aataagcaag ataactgtcg cacctgtatt gcgagcgcgg atgatttgct tttcatctat
     6361 gataaagtct ttgttgagcg tcggaatctc tacctgactg gaaatttccc gtagataatc
     6421 caaatgccct ttaaagaaaa cctcatctgt caacaccgaa atcatcactg ctccgttttc
     6481 ttcataagtc tgggcctgtt gcacaatatc cacatcgaga ttgatatctc ccaaactagg
     6541 gctagctttc ttgacctcag cgattacctg caagcagtcc tgatgattct tcaaaaattc
     6601 tgccaagcga taggtctggc gcagaggctg gatttgctcc agcttcatct gctccacctc
     6661 acgcgccttc tgctctaaga ttcgtgctaa aaattcctga ctcatttttg gtactcctgt
     6721 aacagtctga gtttttcaag ggccttgcct ctagcaatca cttgacgggc caaggcaact
     6781 ccttccttga tgctatcaat cttaccatta gcatagaaac caagaccagc attcaagact
     6841 gtcgtttcca agaatggact tgcttcgttt ttcagaacgc taagcaaaat ttctgcattt
     6901 tcctgagcat tcccaccacg aatatcttcc atagcatagt cttccattcc caaatcctct
     6961 ggagtaaagc ttgacaagct gatttcgcca ttttcaagaa gtgcaatctt ggttgttccg
     7021 ttcaagccag cttcatccaa cccttctggt ccagcaacca cgatggcacg tttgcgaccc
     7081 atatttttca aaacctgagc tgtactttct aggagttctg gacgactaat tccaagaagc
     7141 tgtgtttcta aagccattgg atgaatcagt ggaccagtca agttcataat cgttggaatt
     7201 cccaattcca aacgagctgg catgatgtat ttcatagctg ggtgcatatt tttagcgaag
     7261 agaaagacga ttccagtttt atcaaagacc ttacctagtt cagctggttt gaggtcaaga
     7321 ttgattccca aggcttcgag gacatctgcg gaaccagatt tagaagaaat cgagcggtta
     7381 ccatgcttgg ccatgtgaat accgccacca gccaagacaa aggctgcagt tgtggaaata
     7441 ttaaaactga aagacttgtc cccacctgta ccacagttgt ccatagcatc atgaatctca
     7501 gttggaatat gctgggcatg tcctctcatg acttgggcaa tggctgtacg ttcttcaggt
     7561 gtttccccct tcatcttaag agctaagagg agagaagcaa tctgcgcttc agttacacgc
     7621 ccagttacga tacgctcaat gacatccgtc atttccacac ctgataaatt ttcaaatttt
     7681 gctagttttt caataatctc tttcatccta gtttcctcac tttacaacct tctcgataaa
     7741 attccgaata gaagacaagc cgtctggcgt tccaatgctc tctggatggt actggaagcc
     7801 ataaatcggt aggtttttat gttgaatccc catgatggct tggtcatcag tcgaacgagc
     7861 tgtcacttca aagtcttctg gcatttcctc aatcaaaata ctgtgataac gcatgaccgc
     7921 acgtccatcc tcaatacctt gatacaaaac agatggcgct tcaaagttga tattgctctg
     7981 tttcccatgc atgacttttg gagccaaacc tagcttacca ccaaagactt ctgcaatggc
     8041 ttggtgaccc aaacaaatcc ctagaatcgg cttcttgcct gcaaaatcac aaatcatgtc
     8101 ttccatcttt ccagcatcaa ctggccaacc aggaccagga gaaaagacca gaccatctgc
     8161 tttttcagct tcttcataca gcttggaatc atcatttctc aaaacctgaa cttctgcaaa
     8221 attcccaatg tattgggcca agttataggt aaaagaatca tagttgtcaa tcaataaaat
     8281 catggtctta gttctccaat tctagtcata gattttgctt tgttaatggt ttcttggtat
     8341 tcgttttggg cgatagagtc gtagacaatc cctgccccag cctgcacata ggctctttga
     8401 tttttgagaa tcatggttcg gatggcaatg gccaaatcca tatcacccgt cgcagacaag
     8461 tagccgattg ctcctgcata tacgctccgt ttttccgttt ccagttcata gatgcgtctc
     8521 atagctcgaa tttttggtgc tccagaaacg gttccagcag gaagcgttgc tttcaaggca
     8581 tccatggcag tgagttctgc aagcaaacgt cccttgacca cactggtcaa atgcatgacg
     8641 tagcggaaga gctccacctc catatactta gtaacttgga cactggccgt ttcagagatg
     8701 cggccaatat cgttacgccc caagtctacc aacattcgat gttctgctgt ttccttctca
     8761 tcagagagga ggtcagtcgc caaggccttg tcttcttcat ccgtagcccc tcttggtcgc
     8821 gtccctgcaa tcggattggt tgtcacgatg ccatttttga cagaaaccaa actttctgga
     8881 ctagctccga tgatttgata atccccaaaa tcatagaaat aaaggtaatt agatggatta
     8941 gtcacgcgga gatttctgta gaagtcaaat ggatttccag taacttctgc tgagaaacgc
     9001 tggctgagta cacattggaa catatctccg ttacgaatca agtcacgagc tgtttctacc
     9061 attccctcaa acttatgtgg agcgatatgc ggtttgaagt caagtggtga taaatccaag
     9121 tcttcaaatt catttggagc aggaatgcgt aattcctcaa gcacttggtt caaggatttt
     9181 tccaaggcct cttgactgcg ctcactataa agtgcatcct ctatgacatg tatcttctcc
     9241 ttcttgtggt caaagaccat atagctctca tagacaaaga aatgcatgtc tggcgtccca
     9301 attgtatcct cagggatttg accaatttct tcataaagcg aaatcatatc gtaaccaaca
     9361 aaaccaatgg ctcccccacc aaaagggagg tctgaatggt gctggctctt atgagtcact
     9421 tcataaagga aatccaaggg atcccgatca atcgcttgac cattttgata gagaactcca
     9481 ttttcaaact taatctcaaa aactggatta taggctagga tagaaaaacg agctgtttcc
     9541 ttgtctctcg gaatactctc taaaataacc ttatgttgcc cctttaagcg catataagcc
     9601 aagattggtg ataagacatc tccatgaatg attcgttcca ttgtcatttc cctttcagtt
     9661 ctaattctag ttcgtggcga ctgtatgaaa aatccccacg caaaataact tgcgtgagga
     9721 cgaaattcgc ggtgccacct caattatagg atttctccta tctctcattc ctgtctcaga
     9781 tatctcctgt aacaggctgt gcgataaagg gcactccctt gagaatgatg ttttcttctc
     9841 tcgtttcaga tgaacccaac tttacagctt tctctgcttg ttttcagcaa ccacaagctc
     9901 tctgtgagag aaaagactgt aatttttcca tctattattt tttagcttct agtaatctgc
     9961 aatcgcagct aggtccttgc ctccacgacc agagacattg atgaagagat gttcatctcg
    10021 gtacaccttt atactcttcg aaaatctctt caaaccgcgt caacgtcgcc ttgccgtagg
    10081 tatggttact gacttcgtca gttctatctg caacctcaaa acagtgtttt gagctgactt
    10141 cgtcagttct atccacaacc tcaaaacagt gttttgagca acctgcggct agtttcctag
    10201 tttgctcttt gattttcatt gagtattact agcttttttc gtattagtcc agcctttttg
    10261 tttactttta gtaggaggca aggagctgta gatagaactc aagttcatca aagcgactta
    10321 aggccctaat aaaagataaa ccaaacgacg gatagaaaaa agcccacaca cagaatatac
    10381 ttccgtgtga gggcgttggt aacgcggtgc cacctcaatt ataaagggac tatcccttta
    10441 catctctgcc ttgtttaaca acaagctgca ctgtaaggtg tgcgcaccga attttcattg
    10501 tttcaaattc attttcaaaa tcagcccact ttcactactt ccaaccacct attcacaatc
    10561 accacaggct ccctgaagat caaaaatagt tacttttctg atttgttgaa cttattttaa
    10621 tactttgttt tttctttgtc aagacttttt tacgattttt ttgatatcat tcgaatgtga
    10681 ccatatcttc cttagatcga acatgaacat gtcccacttg ttagaaattg gatccaactc
    10741 aatagaaact gaatggaggc taaacagaac ttattttaga acactccatc ttttccacta
    10801 ggattttcaa gaattaaaca atactagaaa ctctgtctcc taacaaattt aggagaaact
    10861 tcaacagatg tgacactttc ccctttaata attgctaaaa caccttctat catttcttta
    10921 gccaatttaa cataattggg agcaattgta gacaaagctg gagtataata ctgagaaata
    10981 ggaatattat caaatccaat gatagaaata tcatctggaa taagaattcc tttctcatag
    11041 cacgcacgaa tcaagccctg aaccttttca tctcctgaaa caaaaataat gtccggataa
    11101 ttttgggtag tcaagtgctg cattgcataa gaataaactg aatcaattgt agataagcca
    11161 taaatgactt ttaaatccat aaagtaattt ttatcattca gaaaagaacg cacacctctt
    11221 tcacgatcct tattaacatg ggattctcct cccataagca accacatatt tttaaatttt
    11281 tcttcagtta cagctttcat catatcataa gtagcttgaa aattattatt agatacatag
    11341 actactccag acgtttgaga ttcaccgaaa acaagaaaag gcatatggtt cttctttaaa
    11401 tactgaattc tgatatcatc tacactttca taaaaaacaa taacaccatc tactaggcta
    11461 cctgtgcttg atataattga attactaatt gtatcctcct ctccaaagta ctcaactata
    11521 gcattaacac caaattcttt acacgtccgt aacactttat ctaacagcgt atgaaaccaa
    11581 attaaaggaa aagagtcgat tttttttaca gaaatcaata tatttatagc ttctttttta
    11641 gttaaatttt ttgcatacgc atttggaata tacgacaatt cctctataac tttttgaatc
    11701 gcttgataag tttcttcttt aacatttact ccaccattaa taactcgtga aactgttttt
    11761 ggagaaaaac ctgataaacg tgcaatatca taaatagtta cctttttccc atttatattt
    11821 ttcatttcag tcctctatta caaacattct aatattacta tacaatattt aatttttttt
    11881 aacaagagaa tttagtaaat tatttaagat ccacaaattc acaaaattaa ttttacaaat
    11941 attcttcccc ttcaaaaaag tttaaattgc atttcacacc tttattttta agaatgtttc
    12001 caacttcacg acaaataaat tcatatgaga aaaaactacc ataaaattgt agattaactt
    12061 tttcagtaaa atgtgtagga tttataaaaa catataatag cctgtcaatg taacatttta
    12121 acatagagtt aattttttct ttaaagataa catttgttat caactcatca ggaggtaaat
    12181 gaaaggcaaa caccatttca caaatatcat aaaaagaaat aaatttgtat acttgtatca
    12241 aacaattatt atcaaaatat tctattttac ctaaatcaaa attgatttta taatctttca
    12301 taaaaacctc tgagcaaaaa tctactcaaa aattagatga ttaaaatatc taaaaaacaa
    12361 aaggacaaaa acatctgtcc ctttgtttac taaatttcag ctaatttctt cgacataaat
    12421 aacacctaca atattagcaa tttcttccat cagtcgaaga tgttcaaatc tacctgataa
    12481 ttccagagta ataaatgacg ctattttttt atctggaaca tcaaagtatt caattctgtc
    12541 agaattaaca tctccaaacg ctgttcttga atcggtcatt ctgataccat tttctgcaca
    12601 ataaaccaat acacgattat aggcttctgt agatttaact actatataca attcaatcat
    12661 tttagaacga ttttgtagat atttttttag tggttggaac atggatatca caccccaaac
    12721 agaaatggct actaaaagag ctccctcata aaaacctact ccaatagcta atccaattcc
    12781 tgccgaagcc caaatgcctg ctgcagttgt cagacctgta attttctttt tatctgtaat
    12841 aagaatcgtt ccagcgccta gaaaacccac acctgatata acttgagctc ctaatcgtgt
    12901 aggatctcct gtcccaaatt tataagatac gtattcattc gtcatcataa tcaaacatgc
    12961 agctagacaa acaatactat aagttcggat gcctgcaggc tgggatttgc tccctctctc
    13021 taaaccaatt atactaccaa tgactactga taaaacaatc ctgacaacta tttcaatatt
    13081 tgataaccca agactagtgg ctgtcatgat tatttcctta ctttacgccc cggtctttgt
    13141 gtgaagtata ataccgttcc agaaataatc atcagaacaa ttgtataaac aaataccaga
    13201 gcttgtgcat tagatgttgc tgtttcatca cctgcagatc gaatcgtaat acctaatggt
    13261 tgagctaggg ggtggtaaag gaatacagat aagtcgaagt cagttaataa agagttaaag
    13321 tttaaagcaa taacagagag aacaaccggt aaaataaatg gaatgataac cttcatcata
    13381 gtataaaaag gtgaagcacc catacttctt gctgcatctt ccatctcatc atcaacacta
    13441 aataaaatag cacgtaccat tctataagaa aatgggattt ttacaactat atatgcaata
    13501 agtagaatta ccaaactacc taccaaaatc tgattcaaga caagaaattg tggctgatta
    13561 aaagtaaata ataaacttac tgctaaaagt gtacttggta gtaaccaagg aagtagagca
    13621 ccatattcaa ataagaaatc aaaacgagat ttatgttttc tgacaacacg agcaaataca
    13681 actgcgagaa ttgttgctgt tgtcgcagca ataatagaat aaataaagct gaccaagaat
    13741 ggagagaatg ccgcactatt actaaagaat aagcgataat tttctaaagt aaagtttgat
    13801 aatgttaagt tacctgtttg aattgcaact ggatctgtaa atgagtataa tactataaaa
    13861 attagtggaa gcatgaaaac tgtgaacaat ccatatgcta caatgtgagc aatgatattc
    13921 caaggcttag acgcaatttt ttgtttttta agaggcgctt tagtcttaga gatagaaata
    13981 taatttccac ctttttctat cttattcatg atagtaagca aaattgtagt tgcaatacct
    14041 aaaataattg caagtaaggc agctaaatca cgagaattcc ccatccctgc aaatgtaata
    14101 atcattggat ttatagtttg aaattcttta ccaccaacaa tcatgggtgc tgctactgca
    14161 gataaaccac taagaaaaac cataatagta agtgcaaata gagttggaat taaggttggt
    14221 aacactactt ttcggaaaac agtaaatggt tttgctccca tatttcgagc agcctcaata
    14281 gtgtgatagt caacgcttcg aattgtattt gttaaaaaca atgtatgatt agcagttcct
    14341 gaaaatgtca taatgaataa gactgcacca tacccaataa accagttaga gtctaaagaa
    14401 gggataacat tttgtaaaaa ttttgtaatc aatccataag gaccatagac aaatttatat
    14461 ccagtcgcta aaaccactcc tccataaatt aaagaggtca tataacctaa ttttaaaatt
    14521 ttagcacctt taatatcaaa gtactctgta aatagaacac aaagaatacc tacgacatta
    14581 actgtaataa tgagtgaaaa tgctaactta aaactgttca taatactctg aagtgccctc
    14641 tgagatttta gaacacgatg tacagcatca agggaaaatt ctcctccttt tacaaataca
    14701 ttcactacta gatcaaagtt tggataaata ataaatgtta ctaagaacca gattaaccct
    14761 aaacgaataa gccaatcttt taaatttaat ttatgacgca tactgcacct ccttaaaatt
    14821 gcagaacgtc tgatggtgtg ataaataatt ccacactttc tccgacagat ctaatagcag
    14881 cctgactatc aatacttgtt acattaagaa tctgactttc agaaactttt attgtatagt
    14941 gaattgtaac tccagaaaac tcaacatcaa taattgtccc ttttagaata aaatcttgtt
    15001 cagtttcacg attgaatcga actttctcta atcgaatgta acctttttta tcctctaaga
    15061 aaacgcttgt atttttcagt aatacttcgt ggactgtttc atcggtcaaa acattaatat
    15121 ctccaataaa atcacataca aattcagttt gagaattatg ataaatctct actggtgtac
    15181 cgacctgttc gatgtatcca ttgttaaaga ctgcaattct atcagataaa gtcaaggctt
    15241 cctcttgatc atgagtaaca tataaagtag taatacctaa ctctttttga agtcttttca
    15301 actcttttct caaatctaca cgtaattttg cgtcaaggtt tgacaatggt tcatctagac
    15361 aaagaatttt aggttcaaga accagagcac gagccaatgc taccctttgt tgttgacccc
    15421 cagataattc tgatacatta cgctgtaact gttgatcaga gatcttaatt tttgctgcca
    15481 ctgctgatac tttagcttta ataacatctg gagctacctt cttaactttt aaaccaaatg
    15541 caatattatc aaaaacagtc atagttggaa atagcgcata agattgaaat acaataccaa
    15601 ttccacgctt ttcaggttcc aaatgagtga catctgttcc attaacttca atacttcctg
    15661 atgatggatc taaaaaacct accaatgctc tcaaagtagt tgatttacca catcctgaag
    15721 gcccaagaaa tgtaaagaat tccccttcat gtatatctaa attcagatta tcaattgcaa
    15781 caaaatcacc atatttaatt tgaatattat caaatttaat catctcacta actccctcta
    15841 ttactaaaac caaaagcctc tctttatttc ttccttaaat ttagaaataa tagagagact
    15901 tggacataaa aaataactct tatttcttat tttacgtatt ctaattcagc tttttctacc
    15961 cattcatcca aatgctttcc aacagcttcc cagtcaatat tttgtggttt cacttgatca
    16021 acaaattttt tcgtatcttc aggtaactct tttagggcat ctttattggc aggaatagat
    16081 ccaaattttt tactatattc tacttgaatt tctgattgac caaaccaatc aataaattct
    16141 ttagctaacg cttgtttttt actagtgctt aaaaccatag tttgttcagt tacaaatggt
    16201 acaccaatct caggagtcat aactttgaat tcaacatttt gttctttttg tccaattaac
    16261 gctccagaac cccagatcat accgtattga attgggcttt ctttatctaa cgctttaaca
    16321 actgagcttt cacctttttg aagagtatag gcatttgcaa agtattcttt tgcaacttcc
    16381 catccttttt ctgatacgcc taaatctcct ttttcatcaa ggtaacgaac taagatactt
    16441 gctagaattg cccgtcctgt accaccttga agaccataaa ttgaatattt acctttatac
    16501 ttactaccta attcagtcca atctttaggc atttctttta catcaggcgc cccaattaaa
    16561 actaatggtt gaacaatcac aggattataa taattatctt tatctgataa agattgatca
    16621 attttatcta accatttagg cttgtactgt actagtaatt tttgatctct aattttattt
    16681 gagtcaacag caccaattcc aaataccata tctgcaactg cattattctt ctcagcaata
    16741 acacggtctg ctaattgagc gccagcgata tcaaccattt ttatattaaa accagcttct
    16801 tttgctttag cagttaacca atcaccacga ccatttgaga ctgagttcga atagataact
    16861 aattcttgac ttttatcagc tttttcttca gatgaagaag cagtcgtaga atttgaacct
    16921 ccagagcaag cagcaagtgt agtaagagca actcccgttg caagtacagt agaccaaact
    16981 ttcatttttt tcatgataag ttctcctttt ttattatttt atttaaattt ttcgtgatat
    17041 ggaacaaatt gcctcatatc ttcaaataca gtatagtcaa tacggtttac agtaatagtt
    17101 ggaatcttct ctaataaaat ttcagttaat tctgctctga ctttagtaaa ctcttcttcc
    17161 tcctcttcgg ttagaggaat ccgaagatac ccaattgaaa tatggaattg atatctatca
    17221 tgattaggga aacaaacacc tgctttttct gagacataag tacgaatttc ttctaatctc
    17281 tttgcagaag cttcatctgc aggttcaact agtatgtttt gttttcccat ttcagttata
    17341 cgcatatgaa tttcttcatc caacaatgga aaaatttcaa gttgtttagc aaagtaatca
    17401 tgtatttcct gtaaaggtgt atctagagga agattactgc tccaaaactc cgtttcacga
    17461 ttttcatggc acaacaattc aattacagtc atgtgaatag aattccttgg agttaaagta
    17521 aacttatcga taaatggtaa ttctctataa cgtgattgaa taatatcaac aacttccatc
    17581 aaatcttgtt tagtataaag atttgctaca actgtattcc cagggaaatg attaaattcc
    17641 ccattttctt tgaacttaat ttttgttaag tttttcatat aaagaccttc ttttttatat
    17701 ttgacatcgg tgtcattgtg tttacattat acaatgaaac cgtttccttt gtcaagcgct
    17761 gtcaaacatt ttttttaatt tatctttcat taaatatgca tttcattaaa aggttaagta
    17821 atttttccaa aatacagcac tcatatagac agtatcatca attatagcca ttgggatttt
    17881 ttgattgcca attccatgta tctctacaca tgtcttcaat cgattttgtt gtcctccaat
    17941 ttaattcctt atatgctttg tctgcatttg cataacaagt tgcaacgtct cctgaacgtc
    18001 ttggaactat tttataagga atagggatct tattaacact ttcaaatgta tttacaagtt
    18061 gtaatacact agtgccttct cccgagccta ggttatagat ataaacatct gttttttcag
    18121 atactttttc taaagctttt atatgtccta ttgctaaatc tactacatgg atataatcgc
    18181 gcacaccagt accgtcaagc gtatcataat catttccgaa cacacttagt tctgacagct
    18241 tacctaccgc tacttgtgca atatagggca tcaagttgtt aggaattcct gagggatctt
    18301 ccccaatcaa accagactca tgagcaccaa ttggattgaa ataacgaagc aacgcaatac
    18361 tccattctga atctgccaca tgaacatctt ttaaaatttg ctcaagcatc actttcgtat
    18421 acccataagg atttgtcgca cttgtttgca tagtctcaat tagaggtgac tgattgttaa
    18481 ttccatatac agtcgcactt gaagaaaaga caatcttttt aacattaaat tctgacatca
    18541 cttcaacaag tgccaatgta ctcataatat tatttttgta gtacatcaca ggcttttgca
    18601 cggattctcc gacagcttta taacctgcaa aatgaattgc agcatcaatc gattcttgtt
    18661 caaatacctt tctcaatgct ggtttatcac aaacatctaa ttcgtaaaac acgggacgta
    18721 ttcctgtaat tgcttcaata cggtctagca ccaagatgct agagttcgaa aggttgtcga
    18781 caatgatgac ttcctttcct aaatttagta attctactac ggtatggcta ccaatataac
    18841 cagctccgcc tgttaccaat attgccattt ttgtttcctc ctaattaatt ccaaccgact
    18901 taacaaatct cataaacgct tcatgcccag acggtgtatt cttataaact cctgcatctt
    18961 ccagaactct cgcaaacact tgtcctgctt cgtgttgaac tacgctatta acctcttctt
    19021 tattaatgcg aggatatttt tctttcaatt ggtcggccca ttctaaatga taatccgcaa
    19081 ttgcgttatc ctctcctaaa agatattttc caacttcttc taactctggt ttcaaacgag
    19141 gtggtaatat cgcaagtccc atcacttcga ttaacccgat attttccttt ttaatatgtt
    19201 gtacatcttg atgaggatgg aaaacaccat ctgggtactg ttcagtagta tgattatctc
    19261 ttagaacaat atctaattca tatctcccgt ccactttacg agcaatagga gtcaccgtat
    19321 ggtgtgggac atcttcagtc atagcaatga tgtctacttc taaatctgaa tattctctcc
    19381 acttatttag aattttagta gctaaatcta acaagcgatt tttattttca ctttgtaacc
    19441 taattactga cattggccat tttacaatac cagcattaac atcctcaaag tctttaaaac
    19501 gaaattcact ctcaaatttt gctttttcca ttgggaaaat atgtttccct ccctggtagt
    19561 ggttatgact aagaatggag cctcctgaga taggaagatc agaatttgaa ccagcaaaat
    19621 atcctggcaa aatatcaaca atctccaata attgttcaaa tgttttagag gtaatagcca
    19681 ttggtacatg ttgactattt aaaaatatcg catgctcatt aaagtataag tagggagaat
    19741 attggaatcc ccatacttcg tcaccaagtt tcaatcgaat aattctatga ttcgaacgtg
    19801 ctggataatt tattcgcccc tgatatcctt cattttccat acatagtaaa catttgggat
    19861 aattagtggc ttttactaat ttttcagcag caattgtttt tggatctttt tcgggttttg
    19921 acaaatttat cgtaatctct agctctccgt atttagttga tgctcgaaac tcaatattct
    19981 tagcaatagc agaagtttta atataatcac tatctttact taacttataa aactcttcaa
    20041 ctgcttcttg aggtgatata tcatatgaac tccaaaaaat atcatttaat cgactaggta
    20101 aaggaactat gaaattcatt aactctgctc ctaaacattc cttttcctcg attaaatctt
    20161 taattttacc gttttttaag gcgatttcca ctaagtaatc ttttatttgt ttcaggtcat
    20221 tttcatcgga aatgcgatca gttccctcct cacctattaa cgctagtact ctatttttca
    20281 catatatttt gtcaatttca ttatacattc cgtattcaat tactctatca acaaaattat
    20341 caataattgt tttcatatat ttttctttct aatttatgtt cccatatttt ctatacatta
    20401 tccatttata aattgattgc gtagtatgag caattttatc aaggtgatga ataatatcta
    20461 aagcaccaat tacttcagaa acattcccat catcttcaaa tatgtaattc attattttct
    20521 tttcaatatt tgtactaagc tcttctatct cattctgttt ttgtataaca accatatcta
    20581 aacatccaga ttgttcctct ctataacaag atatagccct attcatatgc agtccgataa
    20641 cttcatgaag tatttttatt tctgaaataa ttttcttcaa aatttcatta ttttgaataa
    20701 tctgtagatt ttttaaaatt tcaacaattc tatccccaat acgttcaatg tcagttgata
    20761 tttttattac actaataatt cttcttaagt catatgaaac gggatgttgt aaacaaatta
    20821 actcatatcc ttttttatca acatttagaa ctgactcatt tatgattaaa tcttctttaa
    20881 tcaattctat tcgttcttca tttgataaat attcaaataa cttctcatat ttatcaagca
    20941 cagataccca aatggtctct aaattatttg ataattctat aatttcattt tctaaatata
    21001 accttaacat ttaggtacct cttcttaaca aagttcaata gtaacaatta atattttaaa
    21061 caatatatca aacatcaata actacaatac ttgcatcatc tttctttcca tagattggat
    21121 caatagcaga agaattaaat ctcatcttaa ttaactcttc aaaagtttta ttttgattat
    21181 tttgatagaa ttcataaaag ccatcgctca ttaaaacaat ttgttcacta gtaacatcta
    21241 tttgattaat aatagcatgg tctaaaaatc tctcatccaa cgaacctatc cagtacccac
    21301 tcggttgatt agataatttt ctgatttttt gtaaaataat ttttttattt aaaacactat
    21361 ttgtaccaat tggatctttt atctcatttt tccctttttc aaataagtta tctactctat
    21421 gatccgttat ttccatttcg tttactaaca tgacgcagtc acctagcatc atatactcca
    21481 actttttttc tgaaagttta gcaaatataa aagcaaatgt tggtaagcga taatatagta
    21541 tattgaaact agaatagtac acctctactt ctaaaacatt gttagaaatc gatttgactg
    21601 tcctgattga tttgtcctat tattatttca ttttattata ctctgttaat tcatatgagt
    21661 ttaaaccgat ttcatcttta acctcgagta aagcagtttc aaatatttgt ttaagagttt
    21721 ttgattcttt acaattaacc gacaaacttt ctgataaaat atgtacaact tctgagactg
    21781 aataacctat ctcctcttta gaattatata aatctgtagc tccaccaata atccaaaaat
    21841 actgattttg tgaacctaca atatcctcat tttctacgga acttccttgt atcgaacaaa
    21901 ttttatttat ctttaccata atacttcaac ccttttagtg tcaaaagtaa accaattcct
    21961 gtcactgtta agaatagttc cataatcttg ttcgaaccag tctttggtaa tttttgtttt
    22021 acatctacta tttctttaga tttattaata tgattttcag tttctctgcc atctccaact
    22081 attttatagt ttacttcttc tgtcttatta tcttgtttat tgtcgatctt gtcattcatt
    22141 tgtctattat ctttacttga gttaaactct ccgttcttct ggttactatc aattacatta
    22201 tttgaattag attgtttttc ctctttgttt ttttcttttt cgtttttatc acttaaatta
    22261 tttgttacaa ttttgtaaag cccattctcc gttacaatat tgaaattacc atcgctatca
    22321 cgtataacag gttctttccc atttgcatta gatttgatga atgatatata cttaccggat
    22381 aaattataaa attggttatt taaaacggtt attttaccct ttgaatcctc aataacaatt
    22441 ccttctttac ccccgaatat actattctct gagactacta aattatcact aactcgtaat
    22501 aattcaatat ttggttgttc tgtttcctta gaattattat taattacatt ttttgttaca
    22561 gtaatatctg atacttttcc taaatattct gcactatctt ttgcaactcg tatcgctttt
    22621 gttttaggat cggcaatatt aaatatattt tcggcgataa ccacctgttt atttaaatct
    22681 aataggtctt tagtgttttt atagctataa gcatttacta aagctgctcc gctttctcga
    22741 taatgtacac tctctccttt aactttctta tcaaagcgat ttcctttgat taatacatca
    22801 gtgaatcctg taaaacgtac acctgcatac atcatgttat caaaatgatt atttaaaatt
    22861 ttaatattag aggggttctg tgtcgacaat gtttgatagt gtgtgccaat tgctgttact
    22921 aattccccag atttatcact tttgccaaaa taggaatttt gaatagtcac attttcagat
    22981 tttttcccat catcattcaa ggcataagga aaaccttttc tagttaatgg ttcaatctga
    23041 atgctctcct tacttatgat ttgcccatcc ttcatcgttt tgggtaaggc ttgcccaaga
    23101 aaacgagaat tatcaactaa tacatttttc gaacctgcaa tttgaatagc atgcccttga
    23161 taactatcct tgaatgttac attttttata gttacgttat ttgaattccc aatagcaaat
    23221 gcacctgaag aatttataag tggtagattt tttgctttag ttccttcttc attcaaagca
    23281 ccgttcatat caatcgtacc accagaataa ctaatatctt ctgttgggcc ccattctact
    23341 tgcgcaccat catccgtaaa taaacctgtc ataaaaacaa tggaagggtg attcttaata
    23401 tttataccat ttagaattgt agctttctca ttcaattcta agtgtgtatg actttttaaa
    23461 aaaacaattt cttttactaa ataagttcct tcaggaaaat atacatttcc tccacctagc
    23521 ccttgagctg cagcatctat tgcatcttga attgcttgtc gatcatcatg aatcccatca
    23581 cctaccgcac cataatcttt tacacttaaa gcagtatctt caaattcttt tttgataatt
    23641 ctgtcactta taacatcttc cttataactc ttattttcat tagtagatgt tactgtagat
    23701 tcaactgttc tgttgtctaa ttgtgaattg gaacgaatag taccattaga gctgatgcta
    23761 ttaacactta acgaattatc taaaccatta gtggttgaat tagaggcaat catttcagca
    23821 gaacgattct gattaacagt tggtgaatta tctaaatcat tagtaattgc attagaagac
    23881 tcttttgtag ccatcggtga agaactagta acaacttcat ccgataaaat accttggctt
    23941 cccaaaattg aaattgccaa tagtaccgag caagtcccca cctttaattt acgaatactg
    24001 aatacctcat taggaacaaa atatttcatc agaacctcca atttttttac tatttttaac
    24061 aattgattat tacttttctt aaaatagata gaatgacacc gctgtcatta tctttatcat
    24121 atattttcca aattgaattg tcaaggaata acacaagaaa atattaaaat ttatactctt
    24181 cggaaatctc ttcaaactag gtcagtgccg ccttgcccta agtctaggtt actgacttgg
    24241 tcagttctat agtagactga aactataata gtacacctct acttctaaaa cattgttaga
    24301 aatcgatttg actatcccga tcgatttgtc ctattcttat ttccttttac tatatctaca
    24361 acctcaaagc agggttttga gctatctatg gccaacttcc tagtttgctc tttagccttc
    24421 cattcaaaag tgatgctatc tttcttagct tgaatataaa atatcccatt tactatattt
    24481 aaatttattg atatgttgta aattataaat gaaagaacaa ataccttgtc atacaagcat
    24541 tcgccaggga tatttacctt aatatcgctc atatggcgga ttgaaactaa aacactacaa
    24601 tatatttctt aaatagacct tctataaaag ctagatttaa cctcgataaa aatagatgca
    24661 gtgcttctaa aatactggaa tagggcatat aggtaatcgt agacaagtgt tttatagatt
    24721 gtctcgcagg agatctaatg atgtatagca agcatcacta aacatatggg atatttgcgt
    24781 tattataata tcaacatgct ataaattcta tcatgcaaaa gaatgactag aacatgaaag
    24841 acaggcacaa aactttgaac aatattctga aaacaaaaaa aagacgctag tttccacaat
    24901 ctcactcatg gaaactcacg tctttcaaaa aatagggtga attgaaaact agaacaagac
    24961 actagatttt ctaaatgatg tctagtaagg attctaaatg ctataccaaa ttgctcacat
    25021 cttatttcaa accacgggac tcccacaaga aaggaaaatc ctataaaaat tctctctctg
    25081 aggagaaaga ggcctcaact acaggtgtaa actattatca attgaaaaca acagttttta
    25141 cactcaatta gactttttag gggcaggatc actttcgctt gactgtagtt tgtcattttt
    25201 ttgataaagt tagcactttt tcagaaactg ttttgaaagt ctcaatgata tagtctactt
    25261 cttcatcgct taatttagta tgaagaggga gggtaatttc attctcaaag aaggcatagg
    25321 ccttaggata gttcgtcata tcaaatccaa gattcttata ggctgtcaag agaggaagcg
    25381 gtttgtagtg aacattactt gcaattcctg ctttagccaa ttcttggatg atgaggttgc
    25441 gttcttctag gcttgctcct tctacacggg tgatgtagag gtggcgtgaa gattcgacag
    25501 tttcagtctt gtgtgccaaa ggatggatgc gagaagctgc aaaaccacta tcatagcggt
    25561 ccacaatgtc cttacggcgt tgcaacaaac ttggatagcg gtccaattgt accaaaccaa
    25621 gtgaagccat gatatcggtc atgttgcact tataggctgg tgtaacgata tcgtattccc
    25681 atgaccccag ttgcatcttg gcaagagcat ccttagtttg cccgtgaagg gaaaggattt
    25741 ggaattcctt gtacatctct tcgtcatcaa tcactggatt ggctttccaa gtcgcacttc
    25801 caccttctgc cgttgtaaag ttcttaactg catggaatga gaaggaagta aagtcagcga
    25861 tagaaccaga aggttgtcct ttataaatag atcccaaagc gtgggcacta tcagagacaa
    25921 tgacaatacg gttaaaggcc ttttgccact tgcttgaagc ggtaaagaag tcacgttttt
    25981 tctccacgac ttggaacaaa cggtcataat cgcaaacaat ccctgcgagc tctactggaa
    26041 taatcacctt agttttctca gtgatagctt gctcaagcag gtcatagtcc atctcaaacg
    26101 tatctgcttg gatatccacc atgacagggg ttgctcccac gtgcgtaatg acactacatg
    26161 aagccgtata ggtcatggct ggaacgatga cttcatcacc aggtcccact tccaaaacgc
    26221 gtaaaatcaa ctccagagcg gctgtcgcag agttgagaca aacagtctta ggtgtctgtg
    26281 tgtaaagaga caagcggcgc tccagttctt ttgttttagg acctgttgtg atccaaccag
    26341 aacgcagggt atccactact tcagtaattt ctgcttctgt gatatcaggc ggtgaaaatg
    26401 gaatattgta atttggcatt gatttgctcc ttttatctgt actcattttc ttatgactac
    26461 tttattttag tacctcaaac acggtttgaa acatgatttt gatgtcccca aagaaactaa
    26521 actctcggag ataggcgagg ttatagcgca tcttttcagg aagaacatgc tccacatagg
    26581 cctgatcaac tgacagacct ttctccgtca tttgactgat aattgtgtcc tcatccttgt
    26641 agttgatgct ggctggagag gtaatccctg cttgcaagag caaggttgcc atcatttcag
    26701 ggctatactg ctctgtataa cgtggcactt caggtcgtgt accgacaaag gacatctcac
    26761 ctttaaggac attgaccaac tgaggcagtt cgtccaaacg gacacgtcgg atgaaatttc
    26821 caaccttggt aatgcggcta tcgttagcag aagtcaccag acttcctttt ttatccgcat
    26881 ccgtcaccat ggtacgaaac ttccaaatct tgaaccgacg gttgtactgg gtcacacgct
    26941 cttgcttgta aatcactggc cctttgctat ccaacttgat ccaaatgctc aagatgagaa
    27001 agatgggaga ggtcagaacc agtaagacca aggccaaaac ccagtccaag caacgcttga
    27061 aaatcagcga acccttcctt ttagagacaa gctggtagta agactcaacc tcgcttgatt
    27121 tcatttccac aggcaagtct tcccatttca gcatgctgtt ctcctttgtt tttattatac
    27181 tatttgtcaa catttttcat tataccacaa aatggaaaag gcggtgaaag aaatctgtaa
    27241 tttgaaggat ttccttctag tactcaatga aaatcaaagt acagctttga gattgcagat
    27301 aaagctgaca tggtttaaag agattttcaa agagtatcgg ccatggcccc tgcctgcaaa
    27361 ctatacatct tgtgataggt tactcccaga gccaagagtt cctcatgggt tccactctcg
    27421 ataatgcgtc ccttatccaa gacatagatg cagttggcat cttgaatagt agaaaggcgg
    27481 tgagcgatag caatagttgt tcggccctgt ctcatcttcg ccagagaagc ttgaaccaag
    27541 ctttctgttt cagagtcaat attggctgtc gcttcatcca aaatcaggat tttaggctgg
    27601 ctggcgactg ttctagcaaa ggcaagaagc tggcgttgcc cagtagagaa gctcgaacca
    27661 cgctcggaaa caggggagtc gtacccctga ggaagttctt gaataaagga atctgcatcc
    27721 acaaaggctg ccgcagcctg aacctgctca tcactggttt cttggtacat ggcgatattg
    27781 gacttaatag ttccatgata gaggaagggt tcctgcaaga ccaaaccgat gttttttctc
    27841 agctcttctt gactgaaatc cctgatatcc acatcatcca agagaactct ccctgactgg
    27901 aattcataaa agcgcatgag gacattgata atagacgatt tccctgaacc tgtatgacct
    27961 acaaaggcaa tggtttcacc cttattaaca gagaaagaaa tgtcatccag aatcggatgt
    28021 ttaccgtcat atgagaaaca cacatgttca aaacggatat tgccttcttg gactttggct
    28081 tgcccatttt cttgaagagg ttcataggtc ctctcgtcta tcagggcaaa gacacgacct
    28141 gcagaaacca tagccgtttg cagagttgaa aagttttgcg tcacctcaat caaggggtca
    28201 aaaaggcggt tgatgtactg gataaaggca tacatggtcc cgaccgttat cccgatagaa
    28261 aaaccacggt agccaaagta ggccatcaag actgcatagc ctagaagttt cagcaaactc
    28321 atggcaggtc tcaaaaagag ggcatccaag gctacagaac ggttggcgta gaccaagtgt
    28381 tcttggttga tttcatcaaa ttctgcctgc aggcgcttct cttgattaaa ggcctgaata
    28441 atcctgattc cctcgatatt ctctgccagc ttactattga tatctgacaa gagacttctg
    28501 gttttctcga tgattttcac tgactttttt cgatagagat tgaccaaaag gaaaatcaaa
    28561 ggaagaaaga gcaagactaa agccgtcaaa cgaaaatcca gcaccaacat ggtataaagg
    28621 gttgtcagaa agataaaaac tgctgagata aagctggata aaatcccaga aaacatatca
    28681 ctaatcgtct cggtatcgtt ggtcaaacga gaaacgatag aacctgctgg cgtcttgtca
    28741 aagtaagaca tgcccagttt ctccatattg gcaaaggcat cccgacgaat atccctaaca
    28801 atactgtaag acacgcgcgc aaagagaaga ttgcctacat actgaactac agtttgtagg
    28861 atgtagagac catagtagac cagcaaaacg gtaacggcta gttggttaag attgctgaga
    28921 tactggtcga taaagtggga agccacgagg ggtatgacac ttttaatgac catcgtcgct
    28981 aggagaaaac tgagtgccaa aaaggtcagg agtccataag gcttgagata agacatcaag
    29041 cgcttcaata cagcccattg ttcttgttta ttctgcatct tcttctcctt tcatttccaa
    29101 ctgctgagac tggtaggttt gggcatacca gccatccatc gctagcaagt cttcgtgcgt
    29161 gcctcgttcg ataatttgac cattttgtag aactaaaata aaatctgcat ggacaacagc
    29221 actgaggcga tgggcagtga taatggttgt cttgtccttt cgcgtctcct tgaggttgtc
    29281 gataatcgca tactctgtct tggcatctac ggcggataag gaatcatcca aaatcaagat
    29341 atcagggtct aaaatcatag cccgactcat agccaaccgt tgcttttgac caccagaaag
    29401 actgactcct ttttcaccaa tcagcgtatc aaatccttga ggcatgtcta caatatcttg
    29461 gtaaactcgg gctagcttag tagcttcctc gaccgctgaa aggggcaagt taggattgcc
    29521 aaagcggata ttgtctagga ttgaagtcgc aaagagaaac tggtcctgag gaacatagcc
    29581 catgagactg cgaaggtctg tcagacgata gtcccgaata tcgtgaccgt ttagataaat
    29641 agtaccctta tccacatcgt attcacgcaa gaggagcttg attaaggacg ttttcccaga
    29701 gcctgtctgc ccaaccaagc ccagtgtttg cccttttgcc aaactaaagt gaatatccgt
    29761 cagtgtttcc tcattttcaa aagcaaagct gtcaatggca tactccaaac gcccattttc
    29821 aataccatcc agaggaaact cagggtcttg tacaggagat tcctgagaca aaagattttc
    29881 aatccgctgg taagaaacct tccctcgctg agtagtatta aagaggaaac cgatggccag
    29941 aagaggccag accagcatat ccaaatagct gataaaggtg actagattcc caactgtaat
    30001 ctgcccttcc tgaaccatca aggagccaac caaaagcgtt aaaacatagg acgaaccaac
    30061 aaacaagaga accatagggt caaagagact atcatatttc atggtttgca ggttcttttg
    30121 gaaggttaat tcattgactg cctgaaaaga cttcaactcg tctgcctgat aaccgaaaga
    30181 cttggtcact ttgatacctg atacggactc ctgtaccttg ttattgagtt cagaaaaagc
    30241 agcttgggat tcgccaaagg ccttatgagt ctttctccct aggcgactag tcgtataggc
    30301 catgaaaggt agggggagaa tggcaacaag agtcatctgc catgagatgc taaagagcat
    30361 ggtcaacaaa gtcaccagag ccgtgataga ggcatccacc gcagacatga caccgccacc
    30421 tgctaaacga gtcaaggcat tgatatcatt ggttgcgtgt gccatcagat cacccgtccg
    30481 ataggtttga taaaaggctg acgacatttt tgtgaaatgc ttaaacaagc gagaccgcat
    30541 gatctgtccc aagcaataag aggtcccaag gatatacata cgccacacat agcgcaaata
    30601 gtacatacca aaggctgcaa gtagcaagta aaataggcta agaaggaggt cctgctgagt
    30661 taattgcccc gatgtgatgg catcaatgac tcgccccata accataggag gaatgagatt
    30721 gaggacggaa accaagacca gggccacaat cccgactaga taacggcgtt tttctaactt
    30781 gaaaaaccac cagagttttt gaataatgga cataaaatcc ctttctgatt gcaaatggaa
    30841 acctgaggcc aatactcaat gaaaatcaaa gagcaaacta ggaaactagc cgcaggctgc
    30901 tcaaagcact gctttgaggt tgtagataga actgacgaag tcagtaacct acatacggca
    30961 aggcgacgtt gacgcggttt gaagaaattt tcgaagagta caagacccca ggtttttctt
    31021 attcataagt tacgactgta acagcaccct tgtcatattc agcaataaag atattggcta
    31081 cattgtcatg cccttgttta ctgaggttat caagcaacca ctcttcgcta cgaccaatcg
    31141 attccaagac atctacttga atcacaccgt ctgtcacaac tggatactta ggattttcat
    31201 ctcccatttg cacaacgatg agttgcccat tttgctcttg cacagctcgt ttgacttgct
    31261 tcatctggaa aatcccttgg ctacgaagtt tgagggctac atccgatgca gacaaaccaa
    31321 ctgaacgaca ggcttatggg tcaatattcc catttttgat aaggagagtt ggcttaccat
    31381 caatcaaacg tttcacaaag tgaacattgt tgttgagcta tttgaaagtc aagatcagtt
    31441 tgattaaaat ttcgatataa ttaagtgtca tttgttcaca tccaccagtt caattgcgtc
    31501 tgtcttatac aattcgactt tctctaacag gtacttgtct ggctcacttc cgtttagggc
    31561 acgataatag cgatctccca ccttgataag tgcgccatct gtgtttgtgg aagtattaac
    31621 atagacttct gacttgtcta ctcccaaatc tttggaaaca acctcgatga aatgaagtga
    31681 agtttgaaat ttattgttag aaacttgatt gttttgataa gtcgtgatgc tgaccaaaag
    31741 cagagctaaa taaggccaga gctgaaatca tgaccaactc acgaaatttg gttccttttt
    31801 tatcatggta tgccttgaaa gcaaaaaaaa actgtcacag ctaatagaac aatcccaaag
    31861 ccaaccatga taccattttg ctgaccgatt tggctgagta catagtcata agagtagaat
    31921 ttcatgtatt ttcactccct ttcataaaat cattcttaat tataaacgaa agagagtaat
    31981 ttttcaaacc atacgttggg gaaatagatc tttttttggt ataataaaat ctataatctg
    32041 aatgaaaaag gtaactttat gaaacttatc tcatggaata ttgattccct aaacgctgcc
    32101 ctaactagtg actcagctcg tgccaaattg tcccaagaag tcctacaaac cttggtcgct
    32161 gaaaatgctg atatcattgc tatccaagaa accaagcttt ctgccaaagg acctacaaag
    32221 aaacacgtgg aaattttaga agaactcttc ccaggctacg aaaacacgtg gcgctcttcc
    32281 caagagcctg cccgtaaagg ctatgctgga accatgttcc tttataagaa agaacttaca
    32341 cccactgtca ctttcccaga aatcggtgcc ccttctacca tggacttgga aggccgcatc
    32401 atcactctag aatttgatgc atttttcgta acccaagttt acactccaaa cgctggtgac
    32461 ggtctcaaac gcttggaaga acgccaagtc tgggatgtta aatatgctga gtatttggct
    32521 gaactagaca aagaaaaacc agtccttgcg accggtgact acaacgtagc ccacaatgaa
    32581 atcgaccttg caaatcctgc tagcaaccgc cgttcacctg gatttactga cgaagaacgt
    32641 gctggattta ccaacctttt ggcaactgga tttacagaca ccttccgcca tgttcatggc
    32701 gatgttcctg aacgctacac ttggtgggca caacgcagca aaacttctaa aatcaacaat
    32761 acaggctgga gaatcgacta ctggctcaca agtaaccgta tcgctgacaa ggtcactaaa
    32821 tctgatatga ttgactcagg tgctcgccaa gaccatacac cgattgtctt ggaaattgac
    32881 ttgtaaggat tttctatatg gactacaatg cggtcattcc cgagttgctt gtatcgaata
    32941 tcgaacagtc ccggtccttc tactgtggtt tactgggttt taggattgaa taccaacgtc
    33001 cagaagaaaa ctttctcttg aagagtgtca actaatgtta gaggagggaa caaaggatca
    33061 actagctgaa ctgacctacc cctttggtcg tggagtcaat ctctcctttg gcataaagga
    33121 tgttccaaaa ctctattaaa gagtgatgaa ggcaaactat cctatttatc gtcccttgac
    33181 caaaagaaag tttcgtgtca gtgatcccta tatctatcct cataaatttg cagttttgga
    33241 tccagatggc tattttttaa gatttagcga gtagaataat aaaaattggg aaaagtcttt
    33301 aaagttagaa aaaggcatat tgtcaggtgt ctaaaaactt gatagtatgc cttttatgat
    33361 ggaaaaatct tctaatactc ttcgaaaatc tcttcaagcc acgtcaacgt cgccttaccg
    33421 taggtatatg atactgactc tgtcaattct atccacaacc tcaaaacagt gttttgaggt
    33481 tgtggatagc ttcctagttt gctctttgat tttcatttag tataaatgtt agcttacaat
    33541 ggagtttttg ttcaccccct cttctgtttg ttcgtttttt aaatcaaaac actaacaaaa
    33601 tagttgattt ataaagttat ttagtgtaaa ataaaaacat tggctcaagc ctatttaaaa
    33661 ttgaatatcg ttttacttgt ttatgtcgtg aattggcacg acgtttctac aaggtgccgg
    33721 aacacctaac aataagtaag tcagcagtga gatatggtcg tttttgccat gcctatttgg
    33781 gggacttact tagagattaa gtaggtcctt tttgaatatt tttaatattt cccttaatta
    33841 gtgcggacgg gaggtgaaat tatcctgtga ataatttcag gaattcaggg aatttcatcc
    33901 ctaatttttg agcccctagc tctttcattt ctaggcttag gctaaaatag ttccccgaac
    33961 tattttactc tcaaaaatcc cgtcatagac aataacaaga ttattgtcta tgataccact
    34021 acatcgggaa atatttgata agactattac gagcgaagcg agtcttatca aatatatagt
    34081 attagcaaaa gggatcacta tagaaacatt tcaacaacaa gtaaattagc ttttagactt
    34141 taggaggtct tatgaaatta ttagaagatc gcatcctcaa ggatgggcat atcttgggtg
    34201 ataacatcct caaggtagat tcctttttaa cccaccaagt tgactttagc ttgatgcgag
    34261 agattggtaa ggtttttgcg gaaaaatttg ctgctgccgg cattaccaag gtcgtaacca
    34321 ttgaagcgtc gggtattgcc ccagccgttt ttacagctga agccttaaac gttcccatga
    34381 ttttcgccaa aaaagctaag aacatcacca tgaacgaagg catcttaact gctcaagtct
    34441 actcctttac caagcaggtg accagcactg tttctatcgc tggaaaattc ctctcaccag
    34501 aggacaaggt tttgattatc gacgatttcc ttgctaatgg ccaagctgct aaaggcttga
    34561 ttcaaatcat cgaacaggcc ggtgccacag tccaagctat cggtatcgtg attgagaaat
    34621 ccttccaaga tggtcgtgat ttgcttgaaa aagcaggcta ccctgtccta tcacttgctc
    34681 gcttggatcg ttttgaaaat ggtcaggtcg tatttaagga ggcagatctc taatgcaaac
    34741 tcaagaaaaa cactcgcaag cagccgttct gggcttgcag cacttactag ccatgtactc
    34801 aggatctatc ctggttccca tcatgattgc gacagccctt ggctattcag ctgagcagtt
    34861 gacctacctg atttctacag atatcttcat gtgtggggtg gcaaccttcc tccaactcca
    34921 actcaacaaa tactttggga ttggactccc agtcgttctt ggagttgcat tccagtcggt
    34981 cgctcccttg attatgattg ggcaaagcca tggtagtggc gctatgtttg gtgcccttat
    35041 cgcatctggg atttacgtgg ttcttgtttc aggcatcttc tcaaaagtag ccaatctctt
    35101 cccatctatc gtaacaggat ctgttattac cacgattggt ttaaccttga tccctgtcgc
    35161 tattggaaat atgggaaata acgttccaga gccaactggt caaagtctct tgcttgcagc
    35221 tattactgtt ctgattatcc tcttgatcaa catctttacc aaaggattta tcaagtctat
    35281 ctctattttg attggtctgg ttgttggaac tgccattgct gctactatgg gcttggtgga
    35341 cttctctcct gttgcggtag ctccacttgt ccatgtccca actccactct actttgggat
    35401 gccaaccttt gaaatctcat ctattgtcat gatgtgtatt atcgcaacgg tgtctatggt
    35461 tgagtcaact ggtgtttatc tagccttgtc tgatatcaca aaagatccac tcgacagcac
    35521 gcgccttcgc aacggttacc gcgcagaagg tttggccgta cttctcggag gaatctttaa
    35581 caccttccct tacaccagat tttcacaaaa cgttggtttg gttaaattgt caggcatcaa
    35641 aaaacgcctg ccaatctact acgcagctgg tttcctggtt ctccttggac tgcttcctaa
    35701 gtttggtgcc cttgcccaaa tcattccaag ctccgtcctc ggcggtgcca tgctggtgat
    35761 gtttggtttt gtatctattc aagggatgca aatcctcgcc cgagttgact ttgctaacaa
    35821 tgaacacaac ttccttatcg cagctgtttc aatcgctgca ggtgtcggtc tcaacaacag
    35881 taatctcttt gtcagcatgc cgacagcctt ccaaatgttc ttctcaaacg gaatcgtcgt
    35941 agccagccta ctcgccattg tcctcaatgc cgtattaaat cataaaaaga aataagaaaa
    36001 agaggtgcga gcctcttttt tgtgtgacaa aataaaaaca tctacctatt catatatgct
    36061 agtgtcatag tcctgaaaat catctgcatc aagaacaatt tcacaactct tatacttttc
    36121 tcttacaagt cgttcggctt catctggatt ttcagcctct atacttacta aacgtgataa
    36181 agtttctgta atttctactg tatacttttt cagttttaga ttgctttcca ataattcacc
    36241 tattaacaat aatctatgat aggagctatg tagccactct ggcaatttat ctcctacttc
    36301 ccacccatat ttttccttca tcaaagctag ttgtttttcg tcaccaaatt tcatattttc
    36361 agataaccat ctcacacaat cgggatctga taaggtacag acgattaaac ttaggttatc
    36421 gtaacggctt tcagtttcat aatcaggcca gatgactttt aagaaatcat acacctcttc
    36481 tgatgcaaca agttgtttcg ttttcataat ttccgatact ttcctctacc tttaaattct
    36541 attatttctt tgtctcttaa tatttgaagc tgttgcctaa tcttttcttt gatatgattg
    36601 ttcttaacaa agatattttt taggtcactt tcaaaacgat acatatcttc aagggtaaat
    36661 tctgaaccct ctatcttatc tatacaattt agaatttcta ttgtccaacc tcttgatgac
    36721 agagagctct tccttaaaaa taaaccttgc ttaaattctt ttgtaacttt ttctggatct
    36781 ctaacttgtc catcttgcac aagaaatatc cttcctttag aaggtacttg tgataaatca
    36841 atgttacaac caatccaacc tgctcgtcta gcagttggtg caagtggttt tctttgaata
    36901 atcgatttcg gtgtaacaaa ttgcttcgga aggacaagaa agttatttac ctcaaaattt
    36961 tttgtgtaag ttaaaaaaaa gaaattagga ttattatctg cctgcacacg cttcatcatc
    37021 gttgcataag caccatcatt gattgttgat gaaaaatttc cttttttgct ctttagttca
    37081 aactcctcac tacaatgatt acagtaaaaa tctgctacag gccgattatt ttcaaaatga
    37141 tttaagggat tgttcccaca attagggcaa taagactgac gataaaccca atcctccgtt
    37201 aagatacgtg ccttttggct attactttta taggtttcta ctaattctaa attaaagtgt
    37261 aattccattt aaaaattcct cactaatatg agaactcact cgatataagc aattaaaatc
    37321 tactataact agtataccac atatatgtac ctattacatt tgtatttcat cactctcttt
    37381 tatatttcct tctaacatat ctcataaatt aaaaatgagt gagataaatt tatcccactc
    37441 acctttcttt atatacttac ccgtctttcc tcagaccttt ggcctgtgac aaacatggta
    37501 aaggttgctt tacagacatt tctgccctct tgattggtga tatccacatc catcacacag
    37561 gttgtacgac cttgatggac acattctcct ttaatggtca atacatcgtc gagttttcct
    37621 gccttaaggt agttgataga ggattggagt gtcaccccat caagtcccag cgagataacc
    37681 accaaaccac tgatttggtc acatagcgtg aatagatagc caccatgggc attgccatag
    37741 tagttgagcg acgagttcac tactttggtc gtcaccacaa cgtgaccatc tctcattttt
    37801 tcaatttcgt aattttcaaa ggcagatata gcgtcaaaat gaaagtcttt catcgtttcc
    37861 tcctgatatt tcaaacgaca ctatgatact actttttata ggactgtgca aggagaaagc
    37921 tcctagtcta gtaaaattcc gacatgttcc acaaagcgca taaaggctgt ctgcccttgt
    37981 tctgtctgct tgtagactcc tgcatcctca agtacacgcg caaagatagc acccacagag
    38041 tccttgacga ttgcaagggc tttttcttta tccgttaggt ctggatgttg ggatttgagt
    38101 tggtctgccc actcctgatg ataatcggca actgtaacag cttctcctac aagatagctc
    38161 gcgacttgct ccacttcttc tttcagacgt ggtggcaaga ttgccaagcc catgacctca
    38221 atcaagccga tattttcctt cttgatatgt tggacatcct tgtggggatg atagatgcca
    38281 tcaggatgct ctgctgaagt ctgattgtct cgcaagacca agtccaactc aaactgtcca
    38341 tcacgcttac gcgctattgg tgtgatggtg tgatgcggtg tcccgtctgt ctctgctaaa
    38401 atctgcacac tagaatctga atactgacgc cattcctgga aaatcttatc agctaagtta
    38461 atcaaatcct ctttggaatc cgaagtcaag cgtaggacag acattggcca cttgataatt
    38521 ccagccttga cctgctcaaa accagcaaat cggaaggtct tttgcaaggg agccaattcc
    38581 ataggaaata cgtgacggcc tccctgataa tgatcgtgag ttagaataga gccccccaca
    38641 atcggcaggt cggcattaga tccagcaaaa tatcctggaa actgctctac gatagccaac
    38701 agacgttcaa aactctgacg actaatggcc atgggacgat gctggccatc taaaaagata
    38761 caatgctcat taaagtaagc atagggcgaa tactggaacc cccattcctg accaaccatt
    38821 tcaaaacgga taatccggtg gttgctgcga gctgggtggt tgacccgacc atggtaaccc
    38881 tcattctcta aacaaagttg acactgagga taattactag cttgcaccaa cttggctacc
    38941 gcaatctctt tcggatcctt ttcaggctta gagagattga tggtaatttc aagttctcca
    39001 taatcagatg gaacacgata agcgatattt ttagcaatgg ccttgagttt gatgtaatca
    39061 tttttctgac tgagttgata aaaatcctct atcgcttgct caggagagtg gacataggct
    39121 tcccagaagt cacgattgac ctgactcgga taaggagtca ccaagtccat cagttcagta
    39181 ccaaggattt cacgcgcagt ctgactatcc tcaatcatct ctaatcgaac ggcttcctca
    39241 actagctggt ccttgaggtc aatcaattta tccagattgg tctcaacttc caaaacacct
    39301 tctcccactc gtgccaaaac acggttggtc aggtagattc gatccatttc ctcaaatgaa
    39361 ctttcagaaa tgacatgtgt tacaaattta tctactaaga tcactataga gcctcctttt
    39421 gactagtcaa ggacgcgagt gccacctgca acttcagcga tatagaagct tggagcgtat
    39481 ccaactactt cctcgtagtg tttgcctaca gcttccttaa aggcctcaac agtatctttt
    39541 tgaaccaagg caatggcaca gccaccaaaa ccagcccctg tcatacgagc accgagaact
    39601 ccttcttgtg cccaagctgt gtgaacaaga gtatccaatt ccaaaccagt tacttcataa
    39661 tcatgctcca gagaaacgtg tgacgcattc atcaaacgac caaatgtttc caaatcacct
    39721 gcttgaaggg ctgcttgagc tttaagggta cgttggtttt caagcacagc atggcgagca
    39781 cgtttcaaac gattttcatc tttaatcaaa tagctatatt ggtcaacggc ccactcgtcc
    39841 aattcaccca gggtctgaat atccaaggca acttgcaatt cttccactgc tttttcacac
    39901 tcagcacgac gttcattgta tttagagtcc gccaattcac ggcgtttgtt ggtgttcatg
    39961 ataacaacga cattgtcctt caaatcaagt ggcaccaagt cgtattctaa agtattggta
    40021 tctaagtaaa tagcacgttg gtcagccccc ataccaatag caaactggtc catgatacca
    40081 gagttgactc cgataaagtt gttttctgtt tgttttccga ttttaaccaa atccaaacgg
    40141 tctagtttta aatcaaagag atgctctgcc acgactcctg tcaagagctc caaggatgct
    40201 gaagaagaca aaccagcacc atttgggata ttcccataaa cataaaaatc aaaacctttg
    40261 tcaatcacgt gcccagcttc ttgcaagaaa tgaagaaccc cttttggata attggtccag
    40321 ttgtgctctt tttcaaactt gaggtcagcg agaggcactt cgataatgcc cttgtcctca
    40381 aagttagctg agtagaaacg caagacttgg tcgtcacgct tacgagctgc accgtaagtt
    40441 cccaaggaaa tagcagcagg aaaaacgtgc ccaccgttgt agtctgtgtg ttcaccaatc
    40501 aaattaatac ggcctggtga aaagaaggtt tggtctgctt cttgaccaaa aacagcaaga
    40561 aagtctttgc gaaggacttc agtagtaaga tgttgtgcca tatgaattct cctttgactg
    40621 tccgttaagc catcttaacg tgtaatcgtt ttctttctat tgtatccaag gaatttccca
    40681 aggtcaatcc tttttactaa aattttacta aaatatcagt aaaaagaaga aaaatatgat
    40741 atactaacct aatcaaggag gatttatggc taccttaaaa gacattgcac agctagcctc
    40801 tgtctcaatc gcgaccgtat cccgtgtcct caaccgcgac cagagcctat ctgttacaga
    40861 agaaaccaga caccgtattt taaccgttgc tgaagagcta ggctacacca aacacctcaa
    40921 gacaggcgag tcccacaagc ccaagcaaaa gattgccatt atccaatggg tcagcgaaca
    40981 aggggagcta gacgacctct actactacca gattcgccta ggaatagaaa aaagagccca
    41041 agagttggac tacgatatct tgcgctattt taatgaccat ccttttacct taagcgagga
    41101 agtgattggg attctctgca tcggaaaatt tagccgagct cagatttctg cctttgaaga
    41161 ataccaaaag cctcttgtat ttctagacag cgatacactt tccctgggac atacctgtat
    41221 tatcacggat ttttacactg ctatgaaaca ggttgtcgat tatttcctca gtcaagggat
    41281 ggaccgcatc gggattctaa cagggcttga ggaaacaaca gaccaagaag aaatcattca
    41341 ggacaagcgt ctagaaaact tcaaaaacta cagtcaagcg aggggaatct atcatgatga
    41401 actggtcttt caaggaagat ttactgccca gtctggctat gacttaatga aggaggccat
    41461 tcagagcttg ggagaccaac ttccgccagc atttttcgca gccagcgata gtttagctat
    41521 cggtgctctc cgtgccctcc aagaagctgg aatcagcctg ccagatcgcg tcagcctcat
    41581 ttcattcaac gacaccagtc tgaccaaaca ggtctatcct cccctctcta gtattacagt
    41641 ttatactgaa gaaatggggc gagcaggtat ggatattctt aacaaggaag tcctccacgg
    41701 tcgcaaaatt cctagcctga ccatgctggg aaccagactg acattaagag aaagtaccct
    41761 aaatcaagaa taggataaca taaaaaacga atagagttct aaaactccta ttcgtttttt
    41821 attcgattac aatcatagac ttaatggtct tacgttcatc catatctttg taggcttggt
    41881 cgatatcttc cagtttataa cttgaagtaa agacgcgacc tggattgata tcaccatcaa
    41941 ggacggcttt tagtaaaaat tgcttatcgt atgttgtagc agaagctgcc ccacctgcta
    42001 cagagatatt ttgcataaat gtcgaaccaa gagcacgatt attatagtgt gggactccta
    42061 caaagcccat acgccctcca ttatgaagaa cacctagcgc ctgttctata gcagcctccg
    42121 taccaacaca ttcaagtgct gcgtctgctc ctccaccgag gatttcacgc accttggtaa
    42181 ttccttcttg accacgttct gcaacaacag ctgtcgcacc tgactccata gccatctttt
    42241 gacggtcttc atgacggctc ataaggataa tttgtgatgc tccacgcatc ttagccgcga
    42301 tgacagcaca ttgaccaaca gccccatcac cgataacaac aaccttgtcc cctttttgaa
    42361 catttgcaac acgcgccgca tgatagcctg tcggcatgac atctgcaaga gtcaaaaggg
    42421 acttgagcat cccttctgta tagtcagaag gttgaccagg gattttaacc agcgcccagt
    42481 ttgcatagtg gaagcgaata tattctgcct gaaaatcacc ccccaaatta ttgccaatat
    42541 gattgtcgca agaaccgtca aatccagcaa gacaggcatc acactcacca catccatgtg
    42601 taaaagggac aatcacaaaa tcacctggtt tcaccgtcgt aatggcttcc ccagcttctt
    42661 caacaatccc aatcgcttcg tgtccactat ttttgtgtcc agctttcgtt tctggattac
    42721 ggtacctcca taaatctgaa ccacaaacgc acgcacgaac cacacgaata atcacatcat
    42781 ccgcttctat tatttgcgga cgttcaatgc tagcaagtcc aacctgacct gcctttgtat
    42841 atactgctga tttcatttaa aattttcctt ccttataaag tttaattttg agatttaaac
    42901 gatttaaagc tgtctgtagc tgagacaagc gctcctctaa tttttgcttt tcctcttcta
    42961 aaataccaag cctctcctct ctcgtttcat ctcccttttg gtagagcgac atatagtcaa
    43021 ctaaactatc tacagagaca cccgccgaac gaaaacactt aataaattcc agcgcttcga
    43081 tatcctgatc ttgaaaatca cgaatcccag tagcagtacg agtaatcggt ggcacaagac
    43141 caacccgttc ataataccga atcgtatccg ctgaaattcc caacaaatca ctggcagatt
    43201 taatattcac acgctaacct cctctcattt cattcactga attcacgcta ttctaactca
    43261 cttatcttat tatataactt tgagttgact ccaagtcaag cattttgtat ctaatcgaaa
    43321 aatttttatc attaacaatc atatatctgg agtttataca atgctcttct cttaccaatt
    43381 tttgaaatat ttaaataata aagaaattac tctattccaa ataagatagt acccaagtat
    43441 ttttcacttt tttctaatgt tgatgctcat aactccgttc caagtcacac acctttcgct
    43501 tatgggtttg gtgagtttct aggtcagcat caatttcaat ggtaatattt tgaaaaccac
    43561 aatcttttag gaaaattcga atagactctt tacaagtttc catatgttcc atttctttta
    43621 gacaaacatg gacaatggca tttttttcca aagcatccat agtccagaga ttaagctgat
    43681 taaggctggc cacattgtcc aatcgctcca ggccactctt tacttgcttg atatcaagac
    43741 cttctggcac agcatccaag aaaatcttga gtgtagacca aaaacgtgga agggcttttg
    43801 aaagaataaa gaaagaaatg acaagggaca aaagaggatc taggatatac cagtccgtaa
    43861 atcgaagaac aatcgccatc aggataacag ctacccaccc tagcgtatct tccagaaaat
    43921 gcagactcag aatagactca ttctttgtct ttcccttacc aaccaccaga ctcgctaaca
    43981 gattgatagt aatcgcaata attcctaacc agagaatccc ctcatcattg actggttgcg
    44041 gatgcaaaat cttcgtgaca ttttccaaaa tgactagaac agagcccgtt acgagaatca
    44101 cagctgttac caaggctcct agcaggctaa accgcttata gcccaaggtg tactgattgt
    44161 cttcttcacg attggagatt gtttctagaa aagctgatat tccaattgca atcgcatctc
    44221 ccaagtcatg cacagagtca gcaagaacag cgctagaacc aaatactcca cctgcaataa
    44281 actcaacaat ggcataagtc aaatttaaga aaaaagccac ccaaacagca tattttgcct
    44341 tcatatttct cattcctttg ttataataga tttatgaaca ccttgttcat tatcattatc
    44401 cactaaaact caaagaaagg atagaagcaa aacgtcagct ttattcagtt ctgaacaatt
    44461 tgcctcaagt gtccatatga ctaacattga ccgccgtatc agcaaaacca aaaaagccat
    44521 ctatcaagct tttatacaac ttttgaatgc taagggctac gaggccacta ctgttcagga
    44581 tatcattgat ctcgcagatg tgggacgatc caccttttac tgtcactatg agagtaagga
    44641 gcttcttctg gaccagctct gccgctacct cttccatcat ctttttgaaa gagagcaagc
    44701 catttcaacc gaggactacc tcgcccacct ctttctgcat tttcataaaa accaagacca
    44761 tatcaccagt ctgctatttt ccaaaaatga ctacttcctc cgtcaactcc ataaagagct
    44821 agaacaccat gtctattccg tgctagctga taatttaaaa gaagcccacc ctaatctgcc
    44881 tacttcttac ctccaacact tggtcatgtc caactttatc gagacattga cctggtggct
    44941 caaaaaaggt caagatttca cagaccagga agttgtccaa ttttatctag accttctcat
    45001 tcctaaaaat tgaatataga gtaaagctca gttgtcttat ttctagatta ctgagttttt
    45061 tatcttttca acaacaaaag aggacccgcc gatcctcttt ttcatactat aaatccttga
    45121 ttatcaacta tatctgtttt aatcgaaatc tcaaaacagc actttcaaac atcttttcct
    45181 agttaagtaa atcagtattc tgcttagctg ccttgctcca ttgataccaa ccaactagac
    45241 tgttaatgag ataaattaga tatttccctt gaatttgcag gctttctccc caccagagat
    45301 agattgaaaa gacattggta gccgcccaga atatccactg ttcacggtaa acagctgtca
    45361 tgaggatttg ccctacccca ttggttgcat ctgtgattga atcacgatag ggacgattgg
    45421 caccaataga ctgataaatg aagccaaagg ccaaccacca aagcacacta atggaaagat
    45481 actttgtcca gcccttgccg tccagtttac gcgcgacaaa ctcctgcttt tccttcttaa
    45541 actgtgcctg ataaatccaa actagaagtc caattggctg catgactgtg aagtaaagtg
    45601 tcgtcagcac ctcaccataa aagcctttct gtagggccaa aataaggtaa ataacagagt
    45661 taatcaagcc aaaaagataa ttacttgctc gaccttccga tacaaagatt acacagataa
    45721 tccctgtcaa gctacaaatc atcccaatcc agtcaacaat acgatgttcg taaaccaact
    45781 ccagccagag aggaaaactt cctaaaacca gcaaataaat ccactgggca aaactacgat
    45841 gggcaaagag gtcatcccag atagccttca tagttcctga aaatcctaaa tcagccatag
    45901 ccgcaaccat acgacggtaa ccacctgaca tttcacctag ggttgttttg atattttcaa
    45961 ttttcttttg caaataagta tgcatcattt ctccttttgt ttttaaagag ccgtgtctgg
    46021 atagactttc ggacgcaacg ctctattaga taatgaactg cctatacaca agatttctaa
    46081 ccttagtcga catgagctga aacctcttat ttgttaagta gttcacaaaa tattatacac
    46141 ctattttatg aatagtcaac tgtctttaca gtaaaatttt agaaaatcat gaaaattttc
    46201 tctttctttc cattttaagt gacattcagt cattctcaca tcaaaaaagc ccagacgaaa
    46261 ttgtctgagc attcttttat ctagtcgttt aaggaagttg agttcagtat gtttaaagtc
    46321 tctgtcccat catttcttca acaaaccttg ttcttggaga aactccttgg ctacttgctc
    46381 tgctgacttg ccttcaacac cgacttggta gttgagctgg ctcatctggt tttctgtaat
    46441 cttaccagcc aatgtattaa gaactctttc caactctgga tgtttcttga gaagagcttc
    46501 tttcatgagt ggagcccctt gataaggtgg gaagagttgc ttgtcatctt ccaagacctg
    46561 taaatcataa cgctccaatt ccgcatcagt cgaataggca tccgtgattt gaatatcccc
    46621 tgactgaatt gcctgataac gaagagctgg ctgcatagtc gccacattga gattgagacc
    46681 atacattgat tgcaagccct tatttccatc ttcacggtcg ttaaactcaa gcgtaaagcc
    46741 tgccttcagc tgcccttcca cttttttcaa atccgaaatg gtcttcaagc catattcttg
    46801 agcaatcttt ttcggaacag ctacagcata ggtattttga taagacatag gtttgagata
    46861 ggctagatga tcctgcttgg caatgccatc acgcgccact tgataaacct gctctggctc
    46921 atgactcacc ttgggtgatg gttgaagcaa actttcagtc accgtaccgg taaattcagg
    46981 ataaatgtca atatcacctt ttttcagagc ttcataaagg aaacttgtcg tcccaaaatt
    47041 cggtttaaca gtcgcagtca tgctggtatt ttcttcaatc agcaatttat acatattagc
    47101 caaaatttct ggttctgggc ctattttccc agcaataatc aagttttcct tctctttttg
    47161 agccaaaagg gctggactat aagacagacc cagtaataaa gccaccaagg caaaaccaga
    47221 gaaaatcgtc cgcaatttcg ctttttccat tacttttagt aggaagttaa aggcaatagc
    47281 tagcactgca gaagaaagtg ccccaatcaa aatcagactg gcattattac ggtcaattcc
    47341 caaaaggata aaggaaccta gtccccctgc cccaatcaag gtcgccaagg tagccgtacc
    47401 gataatcaag accgctgccg tccgaattcc agacatgata acaggcatgg caagtggaat
    47461 ttcaaacttc ttgagacgct cccatctggt catcccaaag gcaatcccag cctcttgcag
    47521 actcggatca attccattca gcccagtaat agtattttgt aaaatcggaa aaatcgcata
    47581 aatcactaga gctgtcaatg ccggtaaagt cccaattccc atcaaaggga taaagagccc
    47641 caacaaggcc agagacggga tggtctggaa aatacctgca atctgcaaga cccagtcggc
    47701 cagcttctca tgatagcgaa gataaacagc caagggaatc gcaagcaaaa tagctagtaa
    47761 caaggtcaaa agtgacaact gcaaatgttg agatagggct gtcaaccaat caccaaaacg
    47821 atcctgaaaa gttgcaatta aattagtcat gaatactacc tccaaacaag tctgcaacaa
    47881 agtctgttgc aggagctttt aaaatagtct caggattcga cacctgacga atctctccat
    47941 cctgcaagac agcaatacga tctgccaact ttaaggcttc atccgtatca tgagtcacaa
    48001 aaatcgttgt catcccaaac tctttatgta attcttttgt cagaacctgc aactgttttc
    48061 tcgaaatagc atccaaggct gaaaagggtt catccatgag gagaatcttg ggctgaccaa
    48121 tcatagctcg gacaataccg acccgttgct gttctccacc agatagctca cttggaagtc
    48181 gatgcccata ctcagctact ggtaaaccaa ccttagccaa aagctcttct gttttttgag
    48241 caatttcttc cttagtccaa cccttcattt caggaatgag agcaatattt tcctcaactg
    48301 ttagattggg aaagagagca atagcctgta aaacatatcc agtagaaaga cgaagttcac
    48361 gctcatcata gtctttgatg cgcttcccat ccatataaat atttccatca gttggttcca
    48421 aaagacggtt aatcatcttg agcatggtcg tcttacctga cccagaaggc cctactaaaa
    48481 ccataaattc cccatcctca atctgtaagt tgacatctct caagacatcc ttttctgtgt
    48541 agcgcagtgc tacatttttg tattcaatca ttctttgtcc tcaatttaaa acttccctcg
    48601 attagtcaag tcttctacct taggcatgac ttccttatta tcccaatgct ccacaatttt
    48661 cccgttctct aaacggaaga tatcgtactg ggcataagca acgccatcaa tctgagtctg
    48721 accatagcta accacatagt ttccttgtcc taagagttgg aaaacaaagt caaaagtgac
    48781 actatattca gccacatagt ttttataagc agcacttcct tgtccaatct catgattatg
    48841 ctgaatcaaa tcgtctgcca cataatcact ccactgctct agctccccat tttggaaaat
    48901 ttctgtcaag aaacggcgaa ccagcttttt attttctgct ttcttatcca aatccttgat
    48961 ttcaaaatct ccaaaaattt gatctagttg gtcattttca ggtgttcgat agtagtcaat
    49021 gacatcccaa tgctcaacaa tacgaccatt ctcatccgca cgaaaagtat ccgtcgtcac
    49081 ccattgagct tctccaccat tcagatattg atgaacatga acaaagacca gattgccatc
    49141 ctcaatggtg cggacaatct taatctgacg ctctggatga cgctcaaaga aatctgcaaa
    49201 gaaggctgca aatccttctt tcccgtcagg aacacctgtc gaatgttgga tataggtatc
    49261 ccctacagac tgggcttgag cctcagcaac tcgtccgtct tgaatggcat ggatgtatag
    49321 gttgtgagca tttttcactt gttgtgacat attctaaacc tcatttccct tctctttcaa
    49381 attcgccaaa attctttctt gaaaaccttc aaattggtga atttcttcct ctgaaaatcc
    49441 tttgtaaaag atagtatcca atttctgact gacacgatgc cccacttctt tctgggactt
    49501 gcctaactcc gttaaaacta aatacttctt acgcttgtct tttccacacg gactaacaat
    49561 tacaagcttt tgttcctcta gcttttttat catagtcgtc agcgtattat tcgcaagccc
    49621 agtcgcaagc gcgatatctg tcgcagttgc gcagccagtt tcactattcc ataaaaccgc
    49681 taaaatcttg ccctgttcac ccctataaag agcctcagga tcttgactca gtaacttttg
    49741 aaaaatccgc ccattcaaca aacgaatatg atgggctagc aaatgaccat ctttcataac
    49801 acctccaatt tatttcgata tcgaaatgaa taaaacaatt gtaacactca tcgttctaac
    49861 tgtcaactat ttcgatttag aaataatttt tgataattat ccacaccacc atactccggc
    49921 tcaactaact tttaacgaga gtttctaaac tccttcgtcc tccagtctac aaaagccttc
    49981 cattcgtact atcctatatt ttatgagggg acacattttt cctatcagac catttatttt
    50041 aaagatagaa gtaaatcata attgcttcca tctgttcttt tatagtatat tgaagttaga
    50101 ctagagcact gtatcttcta aaacattgat agaaagcgat ttgaatttcc caatcaattt
    50161 gttcgtattt atagcatttc gaaactggaa taggacacca tgactgctaa aagatttcta
    50221 taaattcatt tgattttcct aatcaatttg ttcatatctt atttcattcc gctataattt
    50281 caccttaccc tatctttttc gtagcaccct tcaaacagcc tatcccctac cgtttgacga
    50341 ttcctcactt cgctccactt ccattacaga agtttcttca ctactatggg ctcggctgac
    50401 ttctcatgat tccttgttac tactatttga acgctcacga gatagatctt acaaaaaatg
    50461 ctttgatcca caatggaatc aaagcatttt aaagagttcc tcatacataa gcgcagaagt
    50521 cgcagttcct ctgtacttgg cttcttctct tttgataaag cgagccaagt tgagcaactc
    50581 aggtgctgga tgtttgggat ttaggagcaa ttcacgattg accaggcctg agagacgaac
    50641 tgcctgcaat tgttcatttg tagtaggcag ttttttagca gtctctagga gagcagcaac
    50701 taaatcttca ctcaaatcat gtcgagcatg attgtaaaga tcttttataa ggctttctag
    50761 gtttggttct gccatcccta ccacctccct tatggtttaa taatgtttaa tcaaatcaac
    50821 cgttgaacga tccaatttct tcaccaaggc ttgtaagaaa gcttgcgctt ctaggaagtc
    50881 atccattgca tagagggttt ggtgagaatg gatataacga gcgcagacac cgatagttgt
    50941 tgatgggaca ccaccatttt tcagatgagc tgcacctgca tctgttccgc ctttaccaca
    51001 gtagtattgg tacttgatac cagcttcttc agccgttgtc aaaagaaaat ccttcatccc
    51061 tgggagaagc aagtgacctg gatcatagaa acgaatcaag gttccatctc caattttgcc
    51121 ttgaccaccg tagacatcac ctgctggtga gcaatcaact gcgaggaaga cttctgggtc
    51181 aaacttggtt gtagaggtat gagcgccacg cagaccaact tcttcttgga cgttagaacc
    51241 cagatagagt tcattgccga gtttttgacc tgataaagct tcagctagct cgcttaccat
    51301 gaggacaccg tagcggttat cccaagcttt tgagatgata tttttttcat tggctgtcaa
    51361 aattgcagaa ctatctggta cgatggtatc accaggacgg atgccaaaac tttctgcctc
    51421 agccttgtcc gcaaaaccac catcaaaaac gatatcggca atggctggca tggttggtcc
    51481 cccctttcca cgagtcaaat gcggaggaac agaacctgaa atcacaggaa tttcatgacc
    51541 atcacgagtc aagagtttga aacgttggct gctaaccacc atggggttcc agccaccgat
    51601 ttctacgaca cggaaggtac catctggctt gatttcgctg accataaaac caacttcgtc
    51661 catatgagaa gcgaccaaga cgcgcggtgc atccacagct tctgaatgtt tgataccaaa
    51721 aataccaccc aagccatctg tcaccacttc atccacatac ggtgtcaact tttcacgaag
    51781 ataagcacgg acaggcgctt catgacctga gactgcagca agttctgtta cttctttaat
    51841 ttttgaaaat aatgttgtca tttcagttcc ttctttcttt catccatttt accacttttt
    51901 ataggagaag gatagtggga aggtggattt ctaagttagt atcttagtcc tgctctatct
    51961 tagaaaagga tagtattctc ttgcatgtag tgcaaaatct agtaaacatt ccaaaattaa
    52021 ctcgaatatt tatttccaaa caaaaaaaca atacaccatc aaagttgttt agatttttca
    52081 tgaaatttac agaaaatagt tgacttccct ttcttctttc tttaaatata tagttggttg
    52141 agtttggaat agtacgctgt agctgctaaa acatttctag aaattaattt gactttccta
    52201 atagagttgt tcatatctta tttcaattta ctatagtaca aaactagaaa aggaaaaaat
    52261 catgaccaaa acaattcttg ttacaggtgg gactagctac attagctccc ataccgttaa
    52321 agctctttta aatgctggct atcaggtgca tgtcctcgat aatctctcca caggaaatcg
    52381 agcggctgtg gatagtcgtg ctagctttaa agaactggat gtttatgatg ctagcgcctt
    52441 aaaggcttac ttagaagaaa atcagattga tgctgtcctc cattgtgcag gtgaaattgt
    52501 tgtgagcgaa agtattgaaa atccaagtaa atacttcact gccaacgttg ctggtatgaa
    52561 ccaagttctc aaagtcttat ctgaagttgg cattcaaaaa atcatgttct cttcgactgc
    52621 ttctctctat ggaaataact gtattgacaa gccggtgact gaagataccc tgctcgaccc
    52681 tgtcaaccct tatgcagaga caaaactgat gggcgaacga atgatttact ggatggccaa
    52741 tcgctacgac tggaaatatg ttattttccg ttactttaat gctgctgggg ctgaaatgga
    52801 tgcttcaaac ggtctgcgtg tgaaaaatcc aactcacatc attccaaata tcaacaagac
    52861 cgcattggga caaaatgata gcttaaaaat atttggagat gactacgata cacgtgacgg
    52921 ttcatgtatt cgagattaca tttatgtctt ggaccttgca taggctcatg ttaaaggaat
    52981 gaactaccta tttcaagaag acagttcttc tcaaatcttt aacttaggaa ctaaaaaagg
    53041 ctatactatc aaagaaatct ttaaaactgc tgaagaatta ctaaattaaa aaatcccaca
    53101 cgagattgtt gctcgacgtg ctagtgaccc agccagtgtc ctagcagatg cttcaaaagc
    53161 taaacaatat cttgattgga cggctagcta ctccctcgaa gatattattt tatcagatta
    53221 aggtaaaaac attttagaat aggataacaa aggagaaagt cttgttgctc tctccttgtt
    53281 gtatttatta aattatcaga aattttattg acagattaga aaaataatgt tacatttata
    53341 tccgcagata tctttcgata ccaaatctac atgaaaggac ggggtatgaa actttctcat
    53401 tatttaattg gcttacttct actcctagtc tttctctcta ttagcattgg gaccagtgat
    53461 ttttcatggg gaaagctatt tgatttcgac cagcagacct ggctcctctt tcaagagtcc
    53521 cgtctcccaa gaactatcag tattctcctg actgcctcta gtatgagtat ggcaggcctt
    53581 ctcatgcaga ctattaccca aaatcagttt gctgcaccga gtacagttgg aacgactgaa
    53641 gccgccaaac tgggaatggt gctgagcctt tttgtctttc catcggctag tctgacccaa
    53701 aagatgctct tcgcttttgt ttcatccatc gtattcaccc tcttcttcct agcctttatg
    53761 accattttta ctgtaaagga aaggtggatg ttgcctctga ttgggatcat ctatagcggg
    53821 attatcggct cagtcacaga agttatcgcc tatcgtttca atctggttca gagtatgact
    53881 gcctggaccc agggctcctt ctccatgatt cagacccatc agtatgagtg gctcttctta
    53941 ggcctcatca tcctgataac cgtttggaaa ttatcccaaa ccttcaccat catgaatctg
    54001 gggaaagaaa ccagcgagag tttggggatt tcctactccc tacttgaaaa actggccctc
    54061 tttctggtgg cgctaacgac aagcgtcacc atgattaccg tgggtggctt accatttctc
    54121 ggagttatcg ttcccaatct tgttcgcaag cgctatggag ataatctaag tcaaaccaaa
    54181 ctcatggtcg cactggttgg tgccaatcta gttctggctt gcgatatcct atcccgagtt
    54241 ctgattaggc cctatgagtt gtctgtcagt ctcttgctag gaatcatcgg tagtctcgtc
    54301 tttatcctac ttctctggag agggggacga aaagatgcag actaaaagca aacataccaa
    54361 gctcttctgg attctcatta ttcttgccat cggagcttgt cttctctact tttggcccat
    54421 cactcacttg tcagcctttg cttggaagtt gcgttcccaa aagatcatcg tttatctctt
    54481 ggtagccatc gcgactggga tttcgaccat tagttttcaa accctgacgg aaaatcgctt
    54541 cctgacgcct agtattttgg gaattgaatc cttctacgtc ctactacaaa ccctactact
    54601 ggtttttgaa agcaagtttc ttcaacttgg caaatcccct atcttagaat tcctagtctt
    54661 acttcttgtc cagtccttct tctttctcgc cttacaaggt tacttgaaga cactgatgaa
    54721 gcaagacctg gtcttcatcc tgctgatctg tctagcgctc agaagtctct ttcgaaatat
    54781 cagcaccttc cttcaagtcc taatggatcc aaacgaatac gataaactgc aaaatagtct
    54841 ttttgcctcc tttcaacatc ttaacacttc catcctagcc atcggttctc tgatcatcct
    54901 cgctttgaca atctttttct ttcgaaaagc agtcgttcta gatgtcttgc acctgcaaag
    54961 agaaacggct cagatattgg gactcgatgt tgaaaaagaa cagaaagagc tcctctgggg
    55021 aatcgtgctt ttgacctcaa cggccactgc cttggtagga cctatggcct tcttcggctt
    55081 tatgctggcc aacctcacct acctgattgt caaagactat cagcacaagt tactctttat
    55141 agtggccatt ctggttggat ttattagctt aaccttgggg caagccttga ttgaacgagt
    55201 ctttgcactg gaaattcgta tcagtatgat cattgagagt gtgggtggct tcttattctt
    55261 tatcttacta tataggaggt ctcgtcagtg aaactggaaa acattgacaa atccattcaa
    55321 aaacaggata ttttgcaagg catttcgctt gaagtcagtc ctcaaaaact gacagccttt
    55381 attggtccaa atggtgctgg aaaatcgact ctcctctcca tcatgagcag actaaccaag
    55441 aaagatcagg gagttctcag tatcaaagga cgtgaaatcg agagctggaa ttcgcaagaa
    55501 ctggctcaag aactaaccat cctaaaacag aaaatcaatt accaagccaa attgactgtt
    55561 gaagaactgg tcagttttgg acgttttccc tacagccgag gtcgacttag atcagaagac
    55621 tgggaaaaaa tccgagaaac tctgaactat ttggaactga ccaacttaaa agaccgctac
    55681 atcaatagcc tgtcaggggg gcaactccag cgcgtcttta tcgctatggt actggcccag
    55741 gatacggact ttatcttgct ggacgaacca ctcaacaatc tcgatatcaa gcaaagcgtc
    55801 agcatgatgc agattcttcg acgactggtg gaggaactcg gcaagaccat tatcatcgtc
    55861 ctccacgata tcaacatggc cagtcagtat gcagatgaaa ttgtcgcctt caaggacggc
    55921 caggtcttta gcaagggaag aaccgatcaa atcatgcagg ctgacctgct cagtcaactt
    55981 tatgagattc ccatcacgct agctgatatc aataacaaaa agatctgtat ctatagctag
    56041 taacataaaa gctcaagtta gagaaccttc agtctcttag tcaataagat taagagactc
    56101 cctaaatcgt tatcacattt taaaaaggag aaattatgaa aacatccctt aaactttatt
    56161 tcactgccct agtggccagc ttcttgctcc tacttggtgc atgtagtaca aactcaagca
    56221 ctagtcagac agagaccagt agctctgctc caacagaggt aaccattaaa agttcactgg
    56281 acgaggtcaa actttccaaa gttcctgaaa agattgtgac ctttgacctc ggcgctgcgg
    56341 atactattcg cgctttagga tttgaaaaaa atatcgtcgg aatgcctaca aaaactgttc
    56401 cgacttatct aaaagaccta gtgggaactg tcaaaaatgt tggttctatg aaagaacctg
    56461 atttagaagc tatcgccgcc cttgagcctg atttgattat cgcttcacca cgtacacaaa
    56521 aattcgtaga caaattcaaa gaaatcgccc caaccgttct cttccaagca agcaaggacg
    56581 actactggac ttctaccaag gctaatatcg aatccttagc aagtgccttc ggcgaaactg
    56641 gtacacagaa agccaaggaa gaattggcca agctagacaa gagcatccaa gaagtcgcta
    56701 ctaaaaatga aagctctgac aaaaaagccc ttgcgatcct ccttaatgaa ggaaaaatgg
    56761 cagcctttgg tgccaaatct cgtttctctt tcttgtacca aaccttgaaa ttcaaaccaa
    56821 ctgatacaaa atttgaagac tcacgccacg gacaagaagt cagctttgaa agtgtcaaag
    56881 aaatcaaccc tgacatcctc tttgtcatca accgtaccct tgccatcggt ggggacaact
    56941 ctagcaacga cggtgtccta gaaaatgccc ttatcgctga aacacctgct gctaaaaatg
    57001 gtaagattat ccaactaaca ccagacctct ggtatctaag cggaggcgga cttgaatcaa
    57061 caaaactcat gattgaagac atacaaaaag ctttgaaata agccacttca aactcaattt
    57121 aatactcaat gaaaatcaaa gagcaaacta gaaaactagc cgcaggttgc tcaaaacact
    57181 gttttgaggt tgcagatgaa agctgacgcg gtttgaagag attttcgaag agtataaaat
    57241 tttgacattc taaaacgcat cctatcaagt tcactcaaac ctgataggat gcgtttttat
    57301 cattttgaaa tctatttacc ccacctcatt ccccttcttg atttcgttta agggaaaagc
    57361 ggtctggaac ggggtcctta cctgttttcg accagggatg acaacgtaaa atccgagcca
    57421 agcccatcaa taccccctta aaaccatgtt tttcaatagc ctgaatcatg tagttggaac
    57481 aagtcagctc aaagcgacaa gagggtggaa agactggtga gataaaacgt tggtaaaagc
    57541 gcacaggcgc tattaaaatt cgtttcatta tttcttagtt acagccatgg tgtgtagttg
    57601 gctgatttct tttttattaa gacgacggga ttctcctgga cggagtcctg tcaagtctag
    57661 gtgtccgaaa cgagtccgag acaacttatc tacttggaga ccaacagctt caaacatctt
    57721 tttaacctga tggttacgcc cttcatggat ggtcaactgc accacagagc gatttttgac
    57781 tgggtccact ttgagaattt cataaacagc tggcttggtt ttcttaccat caatctcaag
    57841 accacgggtc aaggggcgga gattgtcctt attgaccaca cctttaacac gcgcgacata
    57901 aaccttgtca atctcattac gagggtgaat catctcgtct gtaaagtccc catcattggt
    57961 caaaatcaag acacctgatg tatcccagtc caaacgaccc acagggtaaa tacgctcttt
    58021 gacattgggc aagaggtcga caaccgtctt gcgaccctta tcatctgtca cactggaaat
    58081 cacaccgcgt ggtttgttaa gcagatagta gaccttttct tcgttgtaga taggttgacc
    58141 ttcaacttcg accttgtcgc ctgacttgat agtggttgct agttcacgca ccacttggcc
    58201 gttaaccgtc accaagcctt gcttaatcag ctcttctgct tttctcctac tggccacacc
    58261 tgcgtgggca atatacttat tgattctcat cttcttctat cctttcacca aataattggc
    58321 tttcttgggc ttgaatctca agctcatcaa tcactggtaa ttcttctaaa tggtttatcc
    58381 ccatgtaatc taggaaataa tccgtagtca catagaggtt ggggcgcccc aatacttcct
    58441 ttttcccgtc ttcctttatc aggtcaaaag cctgcaactt tgccaaggct ccactcgagt
    58501 taactccacg gatggcatca atttctatcc gcgtaatcgg ctgtttgtag gcaataatgg
    58561 acaaggtctc aagggcagcc cgagacaagc tctggttgat aggcgcctta gagtattcct
    58621 tcaaaatctc tgcaaattga ggcttggtca ccaatctata agcaccactt gtctcaatca
    58681 aagccaaact ggaatctggg tccttttcat acttctgggc taattttcct aaactttgct
    58741 ggatgcctgt cggtggcaga gagaggagtt cagctaactg gcggacccga atcccatctt
    58801 cacccgctac aaacaagagc gcttctattt ttgctaaagt actcatcttt cctctctatc
    58861 aagtctagct ttgaggcact tgactttctt ccttcttttc catgagatag atatctccga
    58921 aactctcctc ttgcacgagg atcagctcct gggttttgat taactctagg gttgccaaaa
    58981 agagggtgat gacctcttgg acattctggg cttccttgaa caaatcctgc aagcgcaatt
    59041 gatctcgtcc aatcaaggac tctttcacga taatcatcat gtcctcaatc ttatactcat
    59101 cccgcaagat cgtcgtgtga ttttgtgcaa actcctcttt tttcttggct aggatatttg
    59161 aaaaagccaa aaagaggtca atggtcgtct tgtcatgcac aagctccgca tcttcgtaaa
    59221 tcaactctgt cggcgctttg gaataatact gggcccgttc ttggtgcttg gcttccaagt
    59281 gctcacccaa gagcttgaac ttgcgatatt cttcgatttg agagaggagg tcctgctcca
    59341 ggtcatcccc caagtctgtc acttctgcta ccttcggaag gagtttacga ctcttaatca
    59401 gcatgagctg actagccatg accatgtact cacccgtcac ttccagacgc atggcctgca
    59461 gggttgagac ataggctaga tactgttcga tgacttccgt aatgggcaca tcgtagatat
    59521 ccatctggta cttagaaacc agatgcaaga gcaagtccag gggtccttca aaatctttta
    59581 atttaatatc cattatctat atttttctaa ggtcaggact gtttttaatc ctaatttttt
    59641 tgcaatttcg tacaaatcga ccttgttttc tatttgtctt agaataaact gttcacgtaa
    59701 gacttgagct gataaggatg gaaaaccttt ctccttgaca aaagattcta actgacgaaa
    59761 ggcccactga cgagaatagg gtttctctcc tctttcaaaa agataggtct gccccatcaa
    59821 gggttccaat tctgaaagca aggccgtggg aatggtgaca atcctctgtt gggaagcctt
    59881 gctgattcgc aacacctgaa aatccagatt gatgtccgca accttgatgg ctaaaatctc
    59941 actgggcaaa agccccattt ctaggattaa gagcgctagc aagcggccct ctggatggtc
    60001 gctttcctgc caaaaagagt ctaggtatag aatctctggc ttttccgtct tcttttcagc
    60061 ttgtttggct aattccaagc ggtaaaagct gtccacctct cctttttgat agagaaagta
    60121 tagaaattgg ttacaggccg aaatctttcg cttctgggcg ctgattttta gattggctag
    60181 ctgggcttgg taaatcttga gactggtctc agaaatccgc tcacctacca tgtctaaaaa
    60241 ttgctccaaa tcatacttat aggactgctt ggaattgaca gacaagccct gcttttcctc
    60301 taaaaaggct gaaatcctgt ctctcattgg catcgaatct catattcctt actaaagtca
    60361 tgcaagaggg cattaacggc cttgaggatg gacttgcgcg taataatccc ttggaaaata
    60421 ccctctgcat ccacaaccgg taagaaggac tcatctacta gcttgtgcaa gacctccgta
    60481 atggtgaaat caggcgaaac aaccgctacg tccgtttttg tcatatgaac gatatccgta
    60541 tccgccatga tttcttggct caagtcatgc tccatctgat aggccataat atctctgagt
    60601 ccaatcgtcc caacaaactg tttttcatct gtcacaacgg gaacacgggt ataggtcatc
    60661 tgactgagca agagggtcgc atgatccgca ttgtgggtat caatcaacac agctagattt
    60721 ttagcagggg tcaaaaaagt ttcctcctgc cccaacaaga aagtctcaaa ctccttggca
    60781 atcatcggct aaactccttg gacaaacctg gatacacctc gtgatctcgt gtcaaaaagt
    60841 ccactttgaa gtaactatca tcaatctcca cacgagcata gagacattct ctgatggtac
    60901 ctcgtggttg gctgatagaa cctggattta gaaagaggat cttgccttcc atccaagcac
    60961 ttggcacatg caagtgacca tagaggcaga tagcggcctc ttcctcctga gcccagtagt
    61021 ccaacttttg aaagttgaaa ttgatgtcaa acaagtgacc atgagtttgg ataatcttgg
    61081 tcgaaccaag ctcagtcacc agacgttctg ggtagccggc gtagaagtcc atgttccctt
    61141 taacaacgcg gatgccctcc caaagtggag aatccggacg tagttcagaa tcgccgttat
    61201 gaaaaacggc atcgactttg cccacatagc gatcacggac ttcttccaca atcaagctat
    61261 cgccatggga atcgctcatt acaatgatgg tttgctttgc catgatggaa atacctccaa
    61321 aagtttctta acggctaagg cacggtgaga ttgactattt ttttcttcca gggttaattc
    61381 agctgatgac tcacctgtct ctcctacaag gaagagggga tcatagccaa agccattttc
    61441 acccttaggt tcaaagttaa tataacctga ccagtctgct tcaacaacta aactttcctt
    61501 atttgggctg gctacgacta gggttgtgtg gaactgagcc gagcggtcct tgagttcaaa
    61561 gaccatggcc aattcgtgca agagtttggc attattttca cggtcagttg ctcccacacc
    61621 tgcgaaacga gctgaccaga cgcctggtaa gccaccaagg acatcgactt tgagaccaga
    61681 atcatctgcc aaaaccatct tgcccgttaa ttgagaaatg gtttctgcct taaggcgggc
    61741 attttcttca aaggtcatac ctgtttctgc tacttcaggc aggtcagggt agtcattaag
    61801 attttccaca tcgtagccta acttatcaaa gatagctcgg aattccttgg ttttaccttc
    61861 gttacgagtc gcaatcaaca aggtttctct gaccttgctt gtctcaaaga aatcatgaac
    61921 attgacccct tctttaggca attctacata caagagttgc ccattttcaa ccaagagcag
    61981 ggccccatga cgttgaataa cttccaagtt tcgtcccatt tcttgattaa gcatgtctac
    62041 cacaaaggag aacaaacggt aggtagaacc atagcgtaaa acagtaactg aaagcgggaa
    62101 accatactct tcatctccaa atattttgga gaattcaaac agaggaaaat ctgtcttata
    62161 gtcgctcaaa ctgttaacgc caccaaaaat actataagac ccaacatacc agtcccggtc
    62221 atccttatat tcataaattt tatttgtcat aattctacat gctccacatg aatctctttt
    62281 tccagccatt cttcaccaat ttgtgcaaaa ctttggctac tggctgttgt gtaaaaacgg
    62341 tgatggagtg gtccagcatc gcgaccacga ttgatttcaa aataattgag taagactgag
    62401 atatcccgta cgcactctgc cccactatcg atgagctgaa cctttggccc catcacattt
    62461 tggataatag ggcgaaggag tggataatga gtacagccca aaatcaggct atccaccttt
    62521 ccaaccaagg gacgcagggt ttcatagacc accttcttgg taacactggt tgacagggca
    62581 cctgactcaa ccaagggagc aaacttggga caggccaagc tctccacctg taagtcggga
    62641 tccagatcat ggattttctg acggtatatg tctgattgta ccgtcatggg cgttccaatc
    62701 actcctattt tcccaccttg actggacttg atggctgccg aagctcctgg caaaattaca
    62761 cccaagacag gaatatctag ttgagccttg atttcttccc agacgaccgc agtcgcagtg
    62821 ttacaagcaa tgacaatcat tttgacatcc ttggtcaaga gaaagttgac cagctgccaa
    62881 gtatattcac gaatttgctc agcaggacgg gggccatagg gcgcccgcgc cgaatctcca
    62941 atatagacga tttcttcatg gggaagctgg cgcatgagct cgcgcacaac ggtcaagccc
    63001 ccgacacccg aatccaaaaa accaattggt cgattatcca tacagtcttc tttctagtct
    63061 tttttctgat tgatcgttca ttatgattcc ttgtactgaa cgaactgacc gacagcttga
    63121 tagaatgtca actacctctc tcttaatcat aatcaaatat caatagaatg caaggaaaaa
    63181 gtctcatccc taaaccataa ccaacatagt gagaagtctg gaactttcat cccagacttt
    63241 tccttattta ttttttcttt ttattgttag caagggctgc cttttgttgg cggatgattt
    63301 ggtggtaaac ttgttgtacc ttagcttcgc ttggtttttg accatttgca ctcaaaagag
    63361 tacgaactgc ttcagcattc aaacgtgggt tgtcagcaaa ttctttttcg atttgcttac
    63421 gaaccaagta cattcctcca agagctcctc ctagaaaagc tagcacaatc aatacaattg
    63481 ctaaaagtaa atccatcatt tttctcctgt ttctttttga gtccctttca ttataccaca
    63541 aactagccac cctgaccagt ttgttctaca ctttcaagga tggaatagac agcaaaaaga
    63601 accctgcttt tctgaaaaag aggtctcctt gctaagttta tactcaatga aaatcaaaga
    63661 gcaaactagg aagctagcca caggttgctc aaagcaccgc tttgaggtta cagataaaac
    63721 tgacacggtt tgaagagatt ttcgaagagt attaatttac ataaatagcc agtgtttgat
    63781 agggtttgag tagaattttc tcagacactt ctgcatcttc atagtttgaa atcaaaatct
    63841 gtccattttg gtagactgct ggcaagtcga tttccacttc tttggcataa aagttattga
    63901 gcactagtaa cttttgatcc tcaaactggc gttcaaaagc gtagacttgt ttgctatctt
    63961 caaaggctgg tttgtaattt ccttctgaaa tgattggcat ttccttacgc agtcgaatca
    64021 agtcttgata gaaggtgaaa atcagacctt tgatttcatt ttctacattg atatctttat
    64081 aggatttacc aactttcaac catggagtgc ctgttgaaaa tcctgcattt tcagaagtat
    64141 cccactgcat gggaatacgt gaattatcac gcgacttagc ttgaataatc tggaaggctt
    64201 cttgctgact ctttccttct tctaagagca tctgataggc attaagcgat tcgacatcca
    64261 cataatcagt catagaatca tagtctgggt caatcatccc gatttcctca cccatgtaga
    64321 tataaggtgt cccacgtgac aggtgaatgc tggctgctag catggtggct ccttccttgc
    64381 ggaagttttg aatatcgaca aaacggttca aggcacgtgg ttgatcgtga ttgttccaaa
    64441 agagggcact ccaaccgtct ttatcactca tttccttacc ccaactatgg taaagactct
    64501 tcaactcttc aaaatcaaag ggagccaagg tccacttttg tccatcctta tagtccacct
    64561 tgaggtgatg aaaattaaag gtcatggata attcctgacg atcaggcgac gaatagagga
    64621 cacagttttc catggtggta gaagacattt ccccaactgt cataaagcta tcgtcagatc
    64681 caaaagtggc ttggttcatc atacgcaaat agttatgaac gatgggtttg tctgtataag
    64741 ctggcttccc ttcattttca ggacagtcca ctgaaacctc gtccttaccg atcaaattga
    64801 tcacatcaaa tcggaaacct ttgacaccct tgtcgcgcca gaaattaaca accttgaaaa
    64861 gctccttacg gacattggaa ttgcgccagt taaggtcagc ctgggtctca tcaaataggt
    64921 gaagatagta tttcccagta tccccgaaag gcgcccatgc agaaccacca aacttagact
    64981 gccaatctgt tggttggtct tggatgaaga aaaagtcttg ataatactta tcaccagcta
    65041 gggctttctg aaaccattca tgctctgtcg aacaatgatt aagtaccatg tccagcataa
    65101 agtcaatctt gtgctcttta ccgacacaca ccatttcctc aaaatcagcc atatcaccaa
    65161 aaagaggatc cactgccata taatctgaaa tatcgtaacc attatcccgt tgagggcttg
    65221 gatagaatgg attgagccag accatatcca cacctagttt ggctaaatag ggaatttttt
    65281 cgataatccc acggaaatcc ccaataccgt tttcagtggt gtctttgtaa gattttggat
    65341 agatttgata gactactttt cctttatcaa gtgtcatctg tttctccttt tctgataaaa
    65401 gggaggaagc agtcttccgt ccctatttgt gctatttcaa ttatactcaa tgaaaatcaa
    65461 agaacaaact aggaagctag ccacaggttg ctcaaaacac tattttgagg ttgcagatag
    65521 agctgacgtg gtttgaagag attttcgaag agtattagat tcgtgtagcg accatgagag
    65581 atgctccagc ttggatcgtt gtcggataag ttccaggaat agtcgctgta taagcatctt
    65641 ggttggtgat gataacagga gtttctgtca ccagacctgc agccttaatg acatccatat
    65701 caaaacgaat cagttgctga ccaactgtaa cgtgatctcc ttggactaca agactttcaa
    65761 aacctttgcc atcaagacct actgtatcca taccgatgtg gatgagcaat tcaactccct
    65821 cgtcagagac aatgccgatg gcatgcttgg tagggaaaag aaccgtcact gtcccattaa
    65881 ctggagaggt caactcacct tggcttggtt caatgaccag accttgcccc atgacacctg
    65941 atgcaaaaat aggattcgtc gcttgactca attctttcac ttggccagtt agtgggctga
    66001 taatttctac cgaagtaagt tctactggtt catggttcac aaattctgct tcttcttgag
    66061 caacgaattc tgcctgcaag ttcgtatcgc cctctgtttt tgtaaagaga ccagccttgc
    66121 ggaagaagaa agtcaagagc attggaacaa caatcgcaac tagcatagtt cctgcaaatg
    66181 gcagcatgta ttgaggttga atagagagaa tacctggcaa accaccgata ccaatagaag
    66241 ccgcagttac attaaaagta acggataaca tgcctgcaag ggctgaacca gtcatcccag
    66301 caacaaatgg ataaatatat tttacgttaa ccccaaaaag agctggttct gtaacaccga
    66361 gataggctga aatggttgca ggaagtgaaa cctgagcctc acgctcatca tggcgatgca
    66421 tgaaataata ggcaaacacg gctgagcctt gagcaatatt agaaagagca atcattggcc
    66481 atagggcagt gccaccagca tccgcaatca attgtgtatc aatggcattg gtcatatggt
    66541 gcagacctgt gatgacaaat ggagcgtaga gggcaccaaa aattgcaccg aagagccatt
    66601 taactggacc agttaaacct gccaagacaa ctgatgaaag tccttgtcca attgtccaac
    66661 cgattggtcc caaaacagta tgagccaaaa tcaaggctgg aatcaatgac aagaaaggta
    66721 caaaaatcat agaaatgact tctgggatat gcttgcgcca gaagatttca agataagaca
    66781 gactcaaacc tgcaagcaag gctgggataa cttgggcttg gtaaccgata cgattaacag
    66841 taaaatagcc aaaattccaa acccagtttg ccgcgatatc agctgctggc gttgaagcaa
    66901 ccgcataggc attgagcaac tgaggcgata ccaaacagat tccgagaaca attcccaaaa
    66961 tttggctggt tcccatctta cgagaaacag accaagtaat ccctactggt aagaactgga
    67021 agatagcttc accaggcaac cagaggaagt gattaacccc tgcccaaaac tgagaggatt
    67081 ctgtgatggt cttgccatcc aacatcgacc aatggacacc ttccaagaca ttacggaaac
    67141 cgaggatcaa tccaccaaca atcaaggctg gaataatcgg agtaaagatt tccgccagag
    67201 tggtcataac acgttggacc acgttttgat tactcttagc tgcagacttg gctgcttctt
    67261 tggaaacacc ctcaatacct gaaacggctg taaaatcatt ataaaagatg ggcacgtcat
    67321 ttccaatgat tacctgaaat tgacctgcat ttgtaaaggt tcctttaaca gctggaattg
    67381 actcgatagc tttaacatta gccttcttat catctcctaa aacaaaccgc atccgtgtcg
    67441 cacagtgagt tacggcagtc acattttctt tgcctccgat tgcctgaagc agatctttgg
    67501 cttcttgttc aaattttccc atttgattct ccttatactt gtcaaagcaa gtttgatttg
    67561 ataagtatat tgtaaacgat accaaacttg tctgcaactt gtttggtata aaaagggtgt
    67621 ttttttgtaa attttctagc acttgtatgg taaaatagat acaggtgttc attaaactag
    67681 actaaaaacc tatttaagca ggcaaaatga agaaatacca acaattattt aagcaaatcc
    67741 aagaaaccat tcaaaacgag acttacgctg tcggagattt ccttcctagc gagcacgacc
    67801 ttatggagca atatcaagtg agtcgtgata ccgtccgaaa ggccctgtct ctcctccaag
    67861 aggaaggatt gatcaaaaag ataagagggc aaggttctca agtcgtcaaa gaagaaaccg
    67921 tcaatttccc tgtatccaac ctaaccagct accaagaact agttaaagaa cttggactgc
    67981 gctctaaaac caacgtggtc agtctggaca agattattat tgataaaaaa tcctcactga
    68041 taaccggttt cccagagttt cggatggttt ggaaggtggt ccgccagcgt gtggtggatg
    68101 atctggtatc cgttctggat acggactatc tggatatgga actaattcca aatctcactc
    68161 gccaaattgc tgagcagtct atctattctt atatagaaaa tggcctcaaa ctccttattg
    68221 attatgctca gaaggaaatc accattgacc actcaagcga ccgagacaag attctcatgg
    68281 acattggcaa agacccttat gtcgtttcga ttaaatcaaa agtctatctc caagacggac
    68341 gccaatttca gtttaccgaa agtcgccata agttagagaa atttagattt gtagattttg
    68401 caaaacgcaa gaaataaaag actgagacac cagatctcag cctttttctt tatcccaaaa
    68461 ctaattcatc actgaccaga ctttggccac tatttttctg gaagagatgc ataaggtctt
    68521 caactgtcag atgctttttc tcttctccct tgacatccac cactatcttg ccttgataga
    68581 gcataatgag acgattgccg tactcaatcg catgattcat atcatgggta atcatcaaag
    68641 tcgtccactg atggtgctcc acaatctttt gcgtcaagtt catcaccatt tgactggttt
    68701 tcgggtcaag tgccgcagta tgttcatcca aaagtaaaag ttttggtttc atcagatctg
    68761 tcatgactag agtcaaagcc tgtctttgtc ctcctgagag atattgagta tctactttta
    68821 agcggttttc aagaccaata ttcaactcct tcaaggcctc ttggaactgg attctatcct
    68881 tctccttcac gccccaacca agccctctct tctgcccgcg tctcaaggca atagccatat
    68941 tctcctcaat cgtcaaacga gaagctgttc ccatcttagg atcttgaaaa acacgggcaa
    69001 tatccttggc tctctttctg acactcagat ttttaatgga tttccctgcc agtagaaggt
    69061 ccccttcgtc caccgataga ttgccagcca agatattcat caaagtggat tttcctgctc
    69121 catttccacc aatcacagag ataaaatctc cctcttcaac ctctaaatct aatcctttga
    69181 ggacatggtt ctcattgacc gtccctgctt caaatgtctt gtgaatattt tcaagtgtta
    69241 acaaacttgt cataactttc tcctcctatt catttctcaa tttcagacca cgaatcttta
    69301 atctcttttg caattctggt gcaaataaaa ccaaagcgag caagattgca ttaaagagac
    69361 gtaccaagtt ttgatctaga tttggaattt catagatatt taaaataatc aaacggtaaa
    69421 caatagcacc gattccgatg gataataagc ggcctccaat ggtcaagtcg tgtatcaaga
    69481 cttccgcaat aatcaccgag ctcaaaccaa caacaatggt tcctgtccca gaagtcacat
    69541 ctgaaaatcc atcattttgg gcaaacaagg aaccacatag agcaatcaaa ccgtttgaaa
    69601 tcatgtaacc aacaatcttc atggtgtcta cattgactcc attggcctca ctcatcggga
    69661 tattatcccc agtcgaacgc aagaccaagc caatctctgt tttcatcaaa agggtcaaga
    69721 ccaaacaaac aagtaaaaaa caggccaaac taagtgagaa aacagttcct tcatttgtca
    69781 gacccaagct cgccaactgt ttaaagacgg ttgcagaatc tcccaaggaa agattgggta
    69841 cactgcccat gattttaata ttgattgaat agagccctgt caaggtcaca atccctgtca
    69901 agagagctgg gattttcatc ttggtgtgga gcattcctga tacaagacct gctaccatac
    69961 ctgccagcaa agcaagtaaa gtcgcaagcc aaggatttgc ccctgcctgt atctgtgata
    70021 caacgactgc tgcccccaga ggaaaggctc cctcagcagt catatccgca atatccaaaa
    70081 tacggaaagt caagtagacc ccaatcgcca caatcgacca caacaaacct tctgataaac
    70141 tagataacac aaaattcatc ttaatcctcc ttattccttg ccttctaact tactaatatc
    70201 aattcccaat gcatctgcca tttcttgatt ggtatgcaat tccagttttt caggcaactc
    70261 aactgctata ttttctggtt tctcaccttt taaaacacga atcagcatgc gagctgtctg
    70321 acgtcccaat tcttcataat tggttccgta gttatacaag ccaccaacag caatcatttc
    70381 tgttgaacca ccgaatactg gaaccttgtg tttaatagaa acctgcttaa ctgtttccat
    70441 ggttaacgaa atgatattat cagttgggac aaaaaccata tccacctctg ccatcaaact
    70501 ctctgctgcc gccttgacgt tattactgtc caagattgtt ttttcaacaa cggtaaagcc
    70561 tttttctttc agaagtcgct tagcttcatc cttttgaaca accgaattgg gctcgctctg
    70621 agtatagagg attccaatcg ttttagcctt tggcaacact ttctttatca aattgatttg
    70681 ggttgaaatg gcatctgatg actgatcgct tgtcccagtt acattgcccc caggatgttc
    70741 tcttgactca accaacttgg cactgactgg gtctgttaca gctgaaaaga taactggtgt
    70801 cgtttgcgtc gtattggcca agctctgagc agaaggcctt gcgatggcta gaacgacatc
    70861 gctggattct gctagttgct gggaaatcgt ttttagattt ctttgttctc cctgtgcatt
    70921 ttgcaaatca atctcaatat tttccccctc aacatagcct tgtttggcca gcttatccac
    70981 aaatccttct ctagtagcgt ataaggactg gtgggtaata aattgcgaaa taccgatacg
    71041 aaagacatct ttttcttatc tgccttcaac tgatgcaaac tgatcagaga agtcaagagg
    71101 agccccacta ccaagagggg gctagtgatt ttcgaacaac tttcataatg aaactccttc
    71161 tcagaaaaga taaaacaaaa aaccgcctag atactatcta aacggatact tgaaataacc
    71221 taacaagtta caacttagct agtccattta gatattcatc tatatggacc acaatcaaaa
    71281 atcttagcca catagataca aacaaattgc ttgaactgtt tgcatccatg gtgacatgtc
    71341 tacaaacact atctaaagta gctaaagtaa aagttttgat tcatagttac ggcttgtctc
    71401 ttattcattt ctttttctgc tttctttttt gatgcttcct gtcctaccac ctttttcatc
    71461 acctgtcaat aacatttcat aatttttaaa atttttcaaa aattctttca ggaagctttc
    71521 aaagtttttc aaatcagtcc aacaaaaaaa gttttataat ttccataaaa attgacatgg
    71581 aaattataaa accattacta gtttagtcct ttttgataac gtgccaattc ggcttggttc
    71641 gcccaaacat agtgacctgg acggatttct accatagatg gcttatcagt ctcatagtcg
    71701 tgttgacttg ggtcgtaaac cttcaagacc ttcttacgtt ccaagattgg atctgggatt
    71761 ggtaccgctg aaagcaaggc ttgagtatat gggtgaattg gattgttaaa caattcttct
    71821 gtttctgcaa cctctacaat aacacccttg taaataactg cgatacgatc tgaaataaag
    71881 cgaacaaccg acaagtcatg ggcgatgaag agataggtca ggccgagctc tttttggaat
    71941 tttttgagca agttcaagac ttgggcacgt acagaaacgt ccaaggctga aattggctca
    72001 tctgcaataa caaagtctgg ttgcatgacc aaggcacggg caataccgat acgttgacgt
    72061 tgaccgcctg agaattcatg agggtaacga gtcaagtgct cagcaagaag acctacttca
    72121 cggataatat tttgaacttt ctctttacgt tcttcttcat ccttaaataa acggtgattg
    72181 taaagacctt cagaaataat ataatcaaca gtcgcacgtt cattcaaact tgcggcaggg
    72241 tcttggaaaa tcatctggat tcgacgaatc aattccgcag cttgttcacg cgatttctta
    72301 ccattaatct tttgaccatc aaaaatgata tctccattac ttgtatcatt tagaccgatg
    72361 atagcacgac caatagttgt tttcccacta ccggactcac ctacaagcga gaaagtttct
    72421 cccttgttga taaagaagtt agcattttta accgcgacaa acttcttact tccttcaccg
    72481 aaggaaattt ctaaatcttt gatttctact aatttttcag acatttcctt cctcctagtc
    72541 agccagatgg gcaaatccca ttttttcacg gatcttatca tggagatttg caatcacagc
    72601 tggtttttct acttttggag catcctcatg aagaagccaa gttttagccc aatgtgtctc
    72661 tgatactgag aattgaggag ctttttgttc gaagtcaatc tgcattgcgt agtcagaacg
    72721 caaggcaaaa gcatcccctt tcaggtcagt ataaagtgac ggaggtgttc ctgggattga
    72781 gtaaagatcc cctttatcat cagcaagctg aggcaagcta gacaagagac tccatgtata
    72841 tggatggcga gggtcataga agacttcctc aaccgttcca tactcaacga tttctcctgc
    72901 atacataacc gctaccttat ccgcaatact tgccaccaca ccaaggtcgt gggtaataaa
    72961 gattgttgtg aaatgatact cgttttgtaa agattttagc aaatcaataa tctgagcttg
    73021 aatagttaca tccaaggcag ttgttggctc atcacagatc aagacatcag gtcggcaggc
    73081 aagggcaatc gcaataacga tacgttgacg cattcctcca gaatattgga atgggtattc
    73141 attaaaacgt ctatctgcgt ctggaatgcc aaccttattc atgtagtcaa tggccaattc
    73201 tttcgcttct ttagctgttt ttccttggtg ttttacaata acttctgtaa tctgactacc
    73261 aattgtttta atggggtcca aactagtcat tgggtcctgg aagatagtcg caatcttagc
    73321 accacgaatt tgttcccaat ccttgtgaga agataaagct gtcaagtcct gaccacggta
    73381 gtcaatacta ccttgggcaa tgcgaccatt ttcttcgagc atacctgtga aggtctttgt
    73441 caaaacagat ttacctgatc ctgactcacc taccaaggct aatacttctc cttcgactag
    73501 ttcaagggaa acgccgcgaa tggctgtcaa tactttgtca cgaacgtcaa attccacgac
    73561 aatatcgcga gcagtcaaaa ttacattttt ttcttttgtc atttctactc ctatctatgt
    73621 gtacgtggat cactagcatc cgctaagttt tgaccaacta cgaaaaggga caaggatacc
    73681 aagacaaggg ttgtcaatgg aatccagaac aagtaagcat tggttgttac gttttgtgaa
    73741 taatccgaaa tcaaacgacc caaacttggc actgtaatcg gtaatccaag accgaagaaa
    73801 gacaagaagg cttcgtatga gataaagctt ggaagcattt gagtcatggt tgtcacaata
    73861 acagatacca attgaggcat gatatttttg gcaacaatct tcaaggttgg tgttcccaaa
    73921 gtacgtgacg ccaagttgta ttccaagtca cgatagcgca agatttgcac acggatcatg
    73981 aaggcaatac caatccatgt tgttacgctc atggcaaaaa tcagattcca gaatccagct
    74041 ccgattgagt aagtcaagac aataacaatc aaaagaggtg ggatgtttga gatgacgttg
    74101 taaacttcca tcatgacacg gtcaactgat tttgaaatac cccaaatacc accgacaaaa
    74161 acaccgataa ccaagttaat cactgtcgca atcacagaaa tgaggatgga gttacgagct
    74221 ccgaaccaga caccgtcaaa gagcgattta ccgttactgt cagtaccgaa ccaatgctcc
    74281 gcatttggct tgatataacg aacactaaag tcgtttacct tgctgacatc attgaaatca
    74341 aacttagaaa acattgggta gatgaaactt atcaaaatga tggctaccaa gattcccaac
    74401 atgactacag ttgatttttt cttcataaat tgtttaaaca ctgatttcca gtaagaatat
    74461 gctggcgcat caatagtttc agaggcaaaa tcgtcacgtt ttacaaactg aaatttttct
    74521 ttatcgattg tagacattat ttgcctcctt tctcagtcaa tttaatacgt gggtcaataa
    74581 tagtcatcca aatatctccc aaaagacgtg agaagataga aatacatgta aagatgaaga
    74641 caagaccaac gaccatagag ttattagatg cttttacaga gtcaatcaac attttaccca
    74701 tacctgggaa ggcgaagact gtttcagtaa gggttgcacc accgataacc ccaataatgg
    74761 caccaggaat tcctgaaacc agcggaacca tggcattttt aaagatgtgt ttgtttgaaa
    74821 tttctttttc agacaaacct tttgcacgag cgaaacgaac aaagtcttga gattgcaagt
    74881 caatcatgta acgacgaatc caaatggctg taccaggagc acccaacaaa ccaaggatga
    74941 ctgctggtaa aacgtaagaa cgccaatctc cagctcccaa gatagggaat gaatctggaa
    75001 gggaaataga tgatccaatc aatcgaacga tgtaaaccaa ggcaatcgtt ggaagagcaa
    75061 gcaagaaggt caaagcccct gttgagaggc tatcaatcca agtgttcttg aaacgagcca
    75121 tggctgaacc aagtggcacg gcaagagcat aggcaagaac caaaccaatc aaaccagtaa
    75181 tagcagagct gacaatcata gatggatatt ggtaattact ttcagtcgct gtataaggat
    75241 catctttccc atagctagct acttcacgag agtcagcctg actaggtgac ttgtaggttc
    75301 ttgagtaaat atttacagaa gacgttttct tacctgttgg gaactgaact tgggcagttt
    75361 tggtttgtcc ttgaccttga gtaataacct gaagaactgg tgtattagca taggttgggt
    75421 aagagtcacc taaattcaag ttcacaaagt tttgatgaac aaatgggaac tgactgttaa
    75481 agtacaagag atatttatgt ttagttcctg aaccgaccaa tgaccatccg atagctggat
    75541 cattttcaaa acgaaggtag cgtttcaagt ctggattttc agggtcttgg attttatttg
    75601 tatggtcaat gtcaatcaag ttagcataga agtgaaaaac acgttcaaaa attggaattt
    75661 cacgagtagc atagaattga ccactttcag taaattctcc caaagtccaa ccatgaccta
    75721 attgattgat gtacttttca taaatagctt tattggtcgc atttgcttct actgttacag
    75781 aagaatccat gctacttgcc ttttcttgca actctttagt atcgtaatac tcaatgtagc
    75841 ccatacgctc aaacacagta ttttcatagt tatcacgttt atcagccgtt gtcgcaattt
    75901 tattatagtt aggatcctgc ttgaaaatca attttcgagg aaccaaggta tagataatcg
    75961 tgtaggtcaa agtcgttact aagaaaatcg aaaccaatga ccgcaaaaca cgcataaaaa
    76021 tatatttttt catattattt cctttaaaaa tcccaaaaga accttctcct catggagaga
    76081 aagttctatt agaaattatt tacttcacat gacttgccaa ttctttttga gctttctcat
    76141 ttgattcagc tttttctttc aaccattttt cacgagcttt ttcatactct tccttagtca
    76201 ccgctttatc ttgtaatttc aaatatttga agtaaacatc tgacccctta gagcctgttt
    76261 gcgcagaagc tccagtaaat ggaacaattc gtgaaagcac tggtgctgca ccagaagaag
    76321 ccatagcagg aataaagagt gaactatctg tcaaccatgc ttgagccgct gcatattttt
    76381 cataacggac attcaagtcg cttgtctctt tggcagcttc atcaactaat ttatcgtatt
    76441 ctttcaaacc aacttgaact actgaagggc tatttggatt atcaaatcct aaatatgttt
    76501 ttgtagtttc actgctagtt gtttttaaaa tatccaggta agtagatggg tcttgatagt
    76561 ctggccccca tgaaactcct cccgatacat cccaatcctc agatgaagca ttggcagcat
    76621 agtaagtaat attaaggaat tcatcacttg tcatttgttg aatatcaaca acgacatttt
    76681 caacaccaag aactgtttct acagattgtt taaaggactg aatacgagat atatagtttt
    76741 ttgatgcttg gtctactgga acgtccagat gaataggaaa ctgaacgccg tctgcttcta
    76801 aagctttctt agctttcgca aactctgcct tggccttgtc agcattgaat aaaccatcct
    76861 gcccatcagc taaattcaca cctttccact catcaccata agcaggaagt tgagcagcga
    76921 ctaaatcacc aaaggtcttc tcaccagctg aaacaaagtc tggttttaca aataaattac
    76981 gaactgctaa agctgctcca tctttaccat tgatttgagc tgagtaagct gagcgatcaa
    77041 gagcaaaatt caaggcttga cggaaatctt tgttaagcaa tgccttctta gtagctactt
    77101 tctctgaatc tgtagtttta gaagtatagt tgtaactttg gcgatcaata ttcacaccca
    77161 gaccagcaat cccagagcct gattgtgtgt aatagatatt gtccttgtat tcttctgcaa
    77221 ccttagaata gttggagctg gtagggtaaa gacgggcata actataagct ccactagtga
    77281 agttacgctc tagcgactcc tgatctgatc catcatagta agctagattg atagtatcta
    77341 ggtggacatt ttctttatcc caatattgct cattttttac aaactctaca gaagattttg
    77401 cagtcaaccc tttcaacaag aatggaccat tataaagcaa ggatgtcgga tctgttggtt
    77461 tagcaaaatc gcttcctttt gatgtttcga attcttcatt cagaggccag aaaatagaat
    77521 aggtcaactt agagttccag aacggttcag gctggttcaa agtgtattgt aacgtataat
    77581 catcaaccgc cttgacacca actgttgaaa aatctgttga agttcctgat agataatctg
    77641 ccaagccttt aaccgaattt tcagctaaat acatagcttc tgatttttta tctgctgcgt
    77701 gttttaaacc gttcacgaaa tctttagccg tcacctctgc atattcttct ccatcagagg
    77761 taaaccattt aaccccttta cgaatcttat aagtgtaggt caaaccatcc ttagagactt
    77821 cccaatcctc tgcaactgca ggagcaagat taccgtaatt atcgttagtg aataaaccat
    77881 caatcccatt tgaagtcact actgttgtac tatttttact tgaaatcagg tagtccaagg
    77941 tttctgggtc tgctgtataa acatagccat aagctttagg ggctgatgaa tcagatgatt
    78001 ttgaagaact gcatgctgca agtacacctg ctgctaataa aacaagacct gctgtagcaa
    78061 atacacgatt ttttttcatt ttctactcct ctgtttatgt gaattataga ttgacaacca
    78121 ttatatcaca ttatccatta aaaatcaaac aaattttcag aatatttagg cttgttggca
    78181 caaatttttc attttttttg aatatatgat tcaaattgtc gttcgaagtg tcaaagacta
    78241 cagtgaaaat aggaaatttg acacagaaat tttggagctt aggaagacat acagtaaaat
    78301 gaaatacgga cggaacaatg tgattttgga attcaaatta aattataaca atattgtaga
    78361 agtatcattc tagtattcaa gattcagttt actatgtctt ttcacaccaa ccttattccg
    78421 aattcaatta ctttcgtgat ttacacatat agattaagac tatcttttat actttaaaat
    78481 ttctcgctac cttgtccact atatgctcct cgctatcacg tttctattca tagcctacga
    78541 tttcactatt gctttctctg acaattctta tttcctgcgt cagacttaaa acgatctatc
    78601 cccagaccat tttaatccgc tacctcacga tagtcaggct tggggagcgc tattgtattc
    78661 accggtagtg gatccctaca gaggacttac acctcagatg cacgacatgc ccatcgtata
    78721 aaaaaatctc ctacccaagg tagaagattt caaacttata aaacttaatc cgtcatgtcc
    78781 gataccaaca ttcgatgctc caatggaata ctgcacataa ctagcaagaa aataaagcct
    78841 gactgaatcc agaagagagc caagtcaaaa attccgtgca cagcaaccac tgtaaggaaa
    78901 gatagataaa ggccgataat cggacgtttc cccgactcct gactcatatc catcatcaag
    78961 cgaacaggag caacagaaga caaaactaat aaaatggtac ccacaattcc gtaactcaga
    79021 atcgtatcaa tataaagact gtgggcatgt tcatgataag gagcatgtat ccgaggataa
    79081 gagtgcatat aggtcaatgg cccttcaccc caaaaaggat tttgcttaaa caaggccatc
    79141 ccagcatccc agatagaaat gcgttcttcc atagaagagt ctaaagtacc cattcgaact
    79201 cccaaatcac tagaaaagag gaaactcaaa ccaatcgcga agaccccaat actaagccaa
    79261 aaggccttcc agtttttaat agtcgtaaag agatagataa ttgctccagc gataatagca
    79321 ggaaaggcag ttcgattttg agtaaagttc aaaccaaaga gattaacaaa gcctgcaatc
    79381 acacagaata ctttcaacca attcaacttg gtcgttgtaa acagatagaa agcaatcata
    79441 atacagaaac aacaaataat tccataataa ttaggattaa agaaggtcac ttctgcccgg
    79501 ttctgatgcc acacctgcat attgggtgaa agaaaagcat agttaaattt cttcacaatt
    79561 tggaaatgtt ctaaactggc aaaagcagct gacaagacac taccaaacaa gacgaactgc
    79621 aaaatcaatc gaaagaattt atgggataaa atcgactgat agtgcaaaaa gaaaatagta
    79681 aatagaaaca ttcctactga agccacaaga cccatccaat tttgtgcaag aatggatata
    79741 acagtactat agctaagaaa aagaagcagc atcggatgct cccccatttt ctgaagaata
    79801 cttttcatgt ctcctgtaaa aatcaaactg ataatatata aacagagtac aactacaaaa
    79861 agataaaagg gtaaaaagat acttaggata attcccaata aaatcagctc tttactagac
    79921 aaccccttca gcttttcaat aaagcctatt gatttcaaaa tgaatccttt ctctccaaat
    79981 cagctgattc agataatagt aagctatcct atattgtacc acttttttag caatttgaaa
    80041 acaaaggaaa cgttttccaa aataaaaacc ctattttatc caccatatca aggcttcaaa
    80101 atgatacttc aactccattc tcaattaccc gataagtctg attttgcaaa tcaatttcta
    80161 ctactgctgt tacggactta tctttatttt gacgtttgat tacaatgctg tgagctgttg
    80221 gtgtctctat ctcagtagtc ccttctagat caaaggcttc tgaacggtta cggaaagaaa
    80281 atagattgag aagggccttc acaacaggtc gttgcacttc ttttgctatt tcctcgttgc
    80341 tatagtaatg acgattaata tttcgacctt ctttagtttc ttctaataat ttcaagtcat
    80401 tcttgcctgc taatagaccc acatagtaaa cctgaggaat acctggggca aaagcttgaa
    80461 ttagacgagc gagaaaatac ttgacatcat catctccaag cgctgaatag taggttgaat
    80521 tgatttggta gatatctaag ttgttatact cggcactaga gtacttacgt ttgacattgg
    80581 ctccaacctt atagagttca tttgaagcat agtcaatctc ctcatcggtc aggatatcct
    80641 tgacatctac tactccaatc ccatcatggg tatctagcat cgtaaattgc ttcatcgggc
    80701 tcatctttaa ccacttagcc aaacgctctg ttctggaact gtaaagagta taaagtgtca
    80761 ccattggaag agcaaaatca taaacatagt aatcatggtc tgctatttta aactgaatcg
    80821 aatagtgttc atgaatctca ggtaaaagct ctgtcccata ctcagcagcg atatctcgaa
    80881 ctttgtccaa taaatcccaa atatctggtt ccacaaagaa atcattagta tccaatttct
    80941 tcactgcata agcaaaggca tctagacgaa tcaaatcaca cccattactt gccaagtgct
    81001 gaatggtctt acggataaat tccatagtta cttctttggt cacatcaaga tcaatctgct
    81061 cctcaccaaa ggtattccac aaatgttcca ctgaaccatc ttcaaacaca atctcttgct
    81121 ttggtgcacg atccttacgc ttgtaaatta aatctacatc agactgtgtc ggacggtttt
    81181 ctggccaaaa cttatcccag tttaaaaaga gagctttaaa ttcactggct tcatgttttt
    81241 cttgatagtc cttataatac ttggattgac gagaaatatg attaatcata aaatcaaaca
    81301 taagataata tttctcacct aaacgcttaa catcctccca atcaccaaaa gctgagtcca
    81361 cttcgtcgta gtcaactggc gcaaatccac gatcacctgt tgatgggaaa aatggtaaaa
    81421 ggtgaactcc tccaatagca tctccaaaat gctcttccaa attatcatat aagtctttaa
    81481 gattatttcc aaggctatca gaataggtaa tcaacatggt tttattttga attggcatca
    81541 ttactctcct ttttctaatt gaagccaagt ctcatatgat ctggcttcat aaataaaatt
    81601 cattttaaat ctctatttat catcaaactc gtactaatat agactgtgat aaacaaagta
    81661 ctactttctt gttttctgca tagaattatc aacaagctaa actcttcctc tgtgtcaaag
    81721 actatagatt ccatgagctc ttcgaaaatc tcttcaaacc acgtcagctt caccttgccg
    81781 tactcaagta cagcctgcgg ctagcttcct agtttgctct ttgattttca ttgagtatta
    81841 cttcactgcc ccgttgctca ttcctgaaat gatatggcgt tggaagaaga gatagacaat
    81901 ggtgatactg ataatgccga ccacgtaaga ggcaaagctt ggtccgtagt cgttgaaata
    81961 ttggcctgcg tagttgtatt ggaacaaagg cagagtccac attttggaat cccggttcaa
    82021 gacaaggagt ggcaacatga agtcattcca gaaccaaagg gcattgataa tcatggttgt
    82081 cgcatgcatc ggtttcatca ttgggaagat gatgcggaaa taggttgtaa attgattagc
    82141 cccatcgatc tctgctgctt catccagact ttctggaatc gagattttga tatagccaac
    82201 atagagaaag agggtctgtg gaatcgcata ggtcaagtag agcaagatca aaccaaaggt
    82261 attagccaaa ccgagtttac tcatcataac cgtaatcgga atcatgatga cttggaaagg
    82321 tacgaagatt ccgaggatta agagggtata catgatggta aaggcttttc ttttactcat
    82381 attgcgagcg atggagtagg ctgccatagg gataaagatc attactgcaa gtaaagacaa
    82441 gacagtgatg acgacagagt tccaataata gcctccaatc ccatcagcta agagacggct
    82501 aaagttgtcc catgtgaagt tggttggaaa gccaaagaaa ttatctacaa tatccttagt
    82561 gggtttgaag gaactaaaga gggtagcaag gagcggcact aaaatcagaa ccgatcctag
    82621 aatcaataga atgtatttgc caatcagggc ttttctttca tcttgtttca tcatgcttct
    82681 cctcttaaat ttcaaatttc ttagatactc tcaattggat gatcgaaatc actacaatta
    82741 agaggaacaa gattacggca atggcattgg cataaccgaa ttggttgttt ttaaaggcat
    82801 agttataaac caagagccca agtgaggttg tggcattgtt tggaccacca ccggtcatgg
    82861 caaagacttg gtcaaaggca gtcagcccac cttttagggc taggataaag accatagaga
    82921 cacttggtag caagtaaggc aattcaatgt tccagaaaac ttgcttgcta gtcgcaccat
    82981 caatccttgc tgcctctgta atctcagttg gaatagattg caaaccagct aggaagatga
    83041 tgatgggcat agccacccct tgccaaagaa ggacaaaggc agccgcaaag attgctcccc
    83101 acttagtccc taaaagactg gtttggagaa attcaatatg aagggcattc ccaatcgctg
    83161 gaagaccgta gttgaagact tgcttgaaga tcaaagccac tgtcaaacca gataaaacag
    83221 ctgggaagaa gaaccaagca cggaagaagg tttggccttt gattttagag ttcaagacac
    83281 gcgcaatgaa gatcccgagt gcaatctcac caaccaccat ggcaatcgta atgattgcgg
    83341 taaagccaat cgcattcatg aattttggat ccatgaagag gagcttaaag ttgtttaagc
    83401 cgacaaattt gtagttataa gtcaatcctg tccagttggt aaaactgtaa aaggctcctt
    83461 gaaacatcgg cacatagaag aaaattgctt gtaacaagag ggggatgacc acaaaagccc
    83521 atgcccaata tttttgtaat acttttttca tagtctctct actcctaatc cacatccgct
    83581 ttcatcgggt taaagaaggc attcaaatca ttgaccatgc cttgtttatc accggtcaag
    83641 acatagttca tggtcaaggt atggaagtct gcttcactgg tccagtattg ttgcaaccag
    83701 accaagtgac gatccgtaaa ggcatattcg gtcataccag caagcggtga atcttctcct
    83761 gcttgtttga ccccttcgat cgctgttgga gatccgtcca catcgtagta tttttgcatg
    83821 acttctggac gggtcatata ttccacaaag gcattggctt cttttggatg tttggtggtg
    83881 gctgagatag accatgccaa gtctcccgca ccaacggtta agctttgtcc tttttctttt
    83941 cctggaatca tgaaggtccc aatcttaaag ttcggttttt gttcattaat cgctgtgatc
    84001 gcccaagacc catttggtgt catgaggaca tccccacgtg cgaaggctcc gataacatcg
    84061 gtatagccag caccttccca gttcttttgc ttagagccat tgatgcgaag gatgtccatg
    84121 accttgatat catctttcat aatcggatcc gacaatttaa tggcatttgg ttgagaataa
    84181 cgaaggtatt gatttgcttc ttttcctcca cctgttgctg tcgcaaaggc taattgattg
    84241 taaccattga gtgtccaagc atctgcacct gcaattccaa atggtgtttg tcctttagca
    84301 acgatatctt tgactaactg ttcaaattca tcccaggttt caggaacctt caagcccagt
    84361 tcttcgaatt tatctttgtt gtagtaaatt ccataagcat tagctgtaaa aggaacgttg
    84421 taaacttttt cgtttacagc atatttttca gcgtagccat ttttcacgcg tttcaggtag
    84481 tctttgttgc tcaaatcttc aaaaacacct gcttttgccc attcttgcag ttcgatggac
    84541 tgtgggtaaa tattgaccac atcaggcaca tctcctgcga gaacgcgtgt cttcaatact
    84601 tcaccagcat ttggtacatt gacgactttg accttgatct tagggttttc cttctcaaaa
    84661 tcacgagtga tttcttccaa ggttttggtc atttcttttt tctggttgaa atactcgatg
    84721 gtcactgtgc catccgcaga tttaccatag ttggagcaag cgccgagccc aaacaaagct
    84781 aaacctgtag ttgcaagaag tccgattttt ttataccatt ccattagaaa gcctccttta
    84841 taaatttata cacccttatt gaactgcacc ccaaaagtta gacagaataa atctaacttt
    84901 tggggtcagt acatatcata gttttctaaa aatatactgt ctactcaaaa aatctccttg
    84961 ggataagata acagttaagc ccgcatacat tagttctgca cctgagtaaa cttcgccatt
    85021 ttcctgtaat ttatatagtc cctcttcatc caaatctttt aattttaaag ttgtttccat
    85081 ggtctctaca acagataaaa cgcgaacgta ggttacaatc gtttgatttc cgtaattaaa
    85141 ttgtacagct gcttcattgg atgcagtatc aggattaatt agtctatact gctgtcctaa
    85201 ctgaactact ggtcgtaatt ctttatacaa gttcacctga ttagcaatcg tagctttctc
    85261 ttcatctgat aaatttgtca aatcaagctc atagcccaaa tttcccatca ttgctacatg
    85321 gccacgtgtt tctaatggtg tcattcgtcc catctgatga ttcggtactg ctgacacatg
    85381 agcccccata gaaatggttg gatagagata ggatgaaccg tattgaattg gtaaacgtgc
    85441 aatggcatca gtattatcac tagcccagac ttgtgggaaa tagcgtatca taccaagatc
    85501 atttcgtcca ccaccaccag agcaggactc aaagagaata tggctgtgct tctctgtcag
    85561 ataagaaacg agttcgtaaa gtcccagcat gtactgatga gattgcatct gtgtctctag
    85621 ataagttaat ccattcccta gcttagtgat attgcggttc atatcccatt taatgtaatc
    85681 aatctcatga taagatagga gttgatctaa gacacttttc aagtattcta ctacctgagg
    85741 attggcaaga ttaagtacta attgattccg agaataagta tgctcataat caggaacctg
    85801 aatagcccag tcaggatgtt gacgatacaa atcactatct acagaaatca tttcgggttc
    85861 taaccaaagt ccaaactgca aacctctttc atggatagct gaaatcagac tttctagact
    85921 tccacccagt ttttcctcat taacaaccca atcacctaaa gcacgattat catcaaaacg
    85981 attgccaaac caaccatcat ctaatacaaa aagttcaatg ccaactttct tagcttcatc
    86041 tgctaactct aacagttttt ctctctgaaa gtcaaagtaa gtagcttccc agttattgat
    86101 tagaattgga cgttcttttt tagaaaattc acttagagta atgtgcttca gtacaaaatt
    86161 ctgactttca tgactaatac cagttaatcc ctgatctgaa tgagtcacta aagctaccgg
    86221 tgtttcaaag tattcctcag gggctaactt ccaagaaaag ttttctggat taatgccaat
    86281 agccacccga acttcattca attgattttt ttgaacaaaa gcttcaaagt tgccactata
    86341 cattagttga atagcaaaca cattcccagc atcctctgtg actccttgtt cgcatagtag
    86401 aagagctggt gtttgagcat gaccagaagc acctcggttt gaactaatcg aaaagattcc
    86461 ttgttctacc tgttgacgtc taacagtctt ttcacgagca taagcaccct gcagagttac
    86521 tatttcgtaa tctgcagctg gaaaatcagc cataaaagaa aaatctttat ggatgacaac
    86581 ttcctgatta ctattattat ctaatttact gtagctagca atagtcgcat cattattaaa
    86641 agtagtataa tacaaagtca gactaagttg agccttagaa tcttctaaca ttaagacaag
    86701 agtctctgta tcgtccatgc tatgtggaga aggtaagccc tgtggaccat tctgaccttt
    86761 taaaatcttt gcttctacaa atcgaaagtc tgttacttca gttacactat gctgaacctg
    86821 tatagttggt ttcctaaaat ctcctaagcc atgttgtcca aaaatctgtc gctgagtatc
    86881 taaactaaag gttcgattag tagccgttgg atttcctgaa aaggcatggt ctcgttcata
    86941 aacactattg gaacctttat agttcttaat agtctttcct aaatgtttca aaagtaagta
    87001 gccatttcga ttttcaataa tcaaacttag atttttactc tcaacataaa atagattatt
    87061 ctctatccta actcccattt acttcacctc atcactttat tgattatatt ttatcacctg
    87121 aaatcgcttt ccaaaataga aaaatgtctc aagaatatgg taaaatgtta ggtaggaggt
    87181 agcacatgct agttttttca gaataccaga ctggaacaat tgaccttgcc ctaagctttt
    87241 atggatatga ggaatgcaca cctaattact cttttggtcc agccattcgt gatacatacg
    87301 tcctacatta cattagtaaa ggacaaggaa aatttcatta caagggtaaa attgttgatt
    87361 taaaagaagg agatttcttt ctattaaaac cagaggaact aaccttttat caagcagata
    87421 gtaaagaacc ttgggcctac tactggttag gaatcactgg agggaaatcc cctgattatt
    87481 ttgctctttc tcaaatttct gatcaatcct atctcatcca atctgaaact tgtcataccc
    87541 agactactgc aaaactcatc tcagacattg tccgcttcgc tcagattaca aaatcaagtg
    87601 aattagctca actccatatc atgggacaac ttcatgaact gatgtttcat ctgggaacta
    87661 ttgctcccaa tcagaaaaaa aagaatattt catcaaccca ccaactctat cttgaatgca
    87721 aacgattaat tgatagccac tatcctcaat cacttacaat tcaagattta gcaaaagaac
    87781 tatccgttca cagaagctac ttatcaagcg tattcaaaga atttaatacc ttatcaccca
    87841 aagaatacct actctacgtt cgaatgcacc gagctagaca acttctcgaa aatacccaag
    87901 agtccatcaa ggtaattgca tactcggtag gtttttcaga tccactccat ttttcgaaag
    87961 cttataaaca atactttaat cagtctccaa gtcatacaag aaaagaatac tctcaatacc
    88021 aactagtgag aaaggcaaca ttatgaaatc ctaccaagct gtctaccaaa tcctatctaa
    88081 agaaaccgac tatatcagcg gagaaaaaat cgcagaaaaa ctatccctaa gccgaacatc
    88141 aatttggaaa gctatcaagc gactagaaca agaaggcatt gaaattaata gtatcaaaaa
    88201 tagaggatat aaactaatga atggtgacct tattcttcca gagattctag aagaaaatct
    88261 tccaattaaa gtcagcttta aacccgaaac aaaatcaaca caactagatg caaaagaagc
    88321 aattgattta ggccatgaag caaatactct ctatctagct tcctatcaaa cagcaggccg
    88381 aggccgtttt caacgttcct tctactcacc acaaggtgga atttatatga cactccatct
    88441 taaaccaaat ctcccctatg acaaattacc atcctacaca ctacttgtag ctggagctgt
    88501 ctacaaagcc attaagaacc taactttaat agatgtcgat ataaaatggg tcaatgatat
    88561 ctatctaaac aatcataaaa ttggaggaat ccttactgaa gcaatgacct ctgtagaaac
    88621 tggcttagtc acagatatca ttattggagt aggtatcaat ttcactatta aagacttccc
    88681 tcaggaatta aaagaaaaag ctgccagctt atttaaagct acagctccta taacaaggaa
    88741 tgaattgatc atagaaatct ggcgtgcttt cttcgaaaca ccagcagaag agctattata
    88801 cctatacaaa aaacagtcat tcattctagg aaaagaagtc actttcacac tagagcaaaa
    88861 agactacaag ggacttgcta aagacatctc agaaaatgga aaacttttag ttcaatgtga
    88921 taacggaaaa gaaatctggc taaatagtgg cgaaatttct ctcaatagtt ggaagtaaaa
    88981 taacacaatt ataatataaa cgatataaaa ataacttcag attagtaatt caattaagtt
    89041 ttacggatct gaagttttat tgtctctaaa aacaaaaaag agagttacaa actctcatta
    89101 aaacggagaa taagggattc gaacccttgc gccagttacc cgacctaacg atttagcaaa
    89161 ccgtcctctt cagcctcttg agtaattctc caattaatgg gcacgagtgg actcgaacca
    89221 ccgacctcac gcttatcagg cgtgcgctct aaccacctga gctacgcgcc caagttaaaa
    89281 aacttggtaa tttgaacaaa gttcaaagcg ggtgacgaga atcgaactcg cgacaacagc
    89341 ttggaaggct gtagttttac cactaaacta cacccgcata aatactatca at
//
LOCUS       DAVHLA010000003        79061 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVHLA010000003 DAVHLA010000000
VERSION     DAVHLA010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 79061)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 79061)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..79061
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.003"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            1..133
                     /locus_tag="VVO77_000248"
                     /pseudo
     CDS             1..133
                     /locus_tag="VVO77_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            136..1149
                     /locus_tag="VVO77_000249"
                     /pseudo
     CDS             136..1149
                     /locus_tag="VVO77_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259617.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Dyp-type peroxidase"
     gene            1124..1702
                     /locus_tag="VVO77_000250"
     CDS             1124..1702
                     /locus_tag="VVO77_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron permease"
                     /protein_id="HEU5692327.1"
                     /translation="MVRNYWKAKSWLLVLALSFLILSPAGAQESLSFFFVKITDASKT
                     VKNGGQTETQKLVTKMASDFERVENKDSEVGKIVKEKLALSGDITEAKLTEISSALLA
                     FEKEQNPVDLDAEKEKLVNRLSPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVV
                     RDNSIAHYGRVETAISFLPSSMEIEPTDESGT"
     gene            complement(1759..2043)
                     /locus_tag="VVO77_000251"
     CDS             complement(1759..2043)
                     /locus_tag="VVO77_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEU5692328.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(2097..3032)
                     /locus_tag="VVO77_000252"
     CDS             complement(2097..3032)
                     /locus_tag="VVO77_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEU5692329.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQKILKQYNITDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKVHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            3136..3579
                     /locus_tag="VVO77_000253"
     CDS             3136..3579
                     /locus_tag="VVO77_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEU5692330.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG"
     gene            3695..3961
                     /locus_tag="VVO77_000254"
     CDS             3695..3961
                     /locus_tag="VVO77_000254"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEU5692331.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            3958..4332
                     /gene="crcB"
                     /locus_tag="VVO77_000255"
     CDS             3958..4332
                     /gene="crcB"
                     /locus_tag="VVO77_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEU5692332.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIFLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLV
                     LYLLLSIGGGLLLAYFLGRKKW"
     gene            4326..4655
                     /gene="crcB"
                     /locus_tag="VVO77_000256"
     CDS             4326..4655
                     /gene="crcB"
                     /locus_tag="VVO77_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEU5692333.1"
                     /translation="MVIVYLAIACGFGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            4774..5121
                     /gene="rplS"
                     /locus_tag="VVO77_000257"
     CDS             4774..5121
                     /gene="rplS"
                     /locus_tag="VVO77_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEU5692334.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            5163..5234
                     /locus_tag="VVO77_000258"
     tRNA            5163..5234
                     /locus_tag="VVO77_000258"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5196..5198,aa:Arg,seq:cct)
     gene            complement(5289..6095)
                     /gene="yidA"
                     /locus_tag="VVO77_000259"
     CDS             complement(5289..6095)
                     /gene="yidA"
                     /locus_tag="VVO77_000259"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEU5692335.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETDTGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGTYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYEHYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTLVL"
     gene            complement(6108..7412)
                     /locus_tag="VVO77_000260"
     CDS             complement(6108..7412)
                     /locus_tag="VVO77_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEU5692336.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSHRFVNRKVFKSITFSQEDQDQLTSMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            7484..7861
                     /locus_tag="VVO77_000261"
     CDS             7484..7861
                     /locus_tag="VVO77_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEU5692337.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTNRYQVDGQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            7952..8284
                     /locus_tag="VVO77_000262"
     CDS             7952..8284
                     /locus_tag="VVO77_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEU5692338.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDDFLQEQIEI
                     LTSIDNRE"
     gene            8296..9867
                     /gene="ffh"
                     /locus_tag="VVO77_000263"
     CDS             8296..9867
                     /gene="ffh"
                     /locus_tag="VVO77_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEU5692339.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKVLAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(10062..11345)
                     /locus_tag="VVO77_000264"
     CDS             complement(10062..11345)
                     /locus_tag="VVO77_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEU5692340.1"
                     /translation="MKQESTVDLLLDVDQRPSAGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMLATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLEANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(11599..12312)
                     /gene="rsmG"
                     /locus_tag="VVO77_000265"
     CDS             complement(11599..12312)
                     /gene="rsmG"
                     /locus_tag="VVO77_000265"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEU5692341.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            12406..12966
                     /locus_tag="VVO77_000266"
     CDS             12406..12966
                     /locus_tag="VVO77_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEU5692342.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            12968..13867
                     /gene="htpX"
                     /locus_tag="VVO77_000267"
     CDS             12968..13867
                     /gene="htpX"
                     /locus_tag="VVO77_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEU5692343.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSGMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(13911..15470)
                     /locus_tag="VVO77_000268"
     CDS             complement(13911..15470)
                     /locus_tag="VVO77_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU5692344.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLTMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLSKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYISKTGEKEELQKIHSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(15709..16026)
                     /locus_tag="VVO77_000269"
     CDS             complement(15709..16026)
                     /locus_tag="VVO77_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEU5692345.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EQLNNSILIDLEKFYQPTSLLIGLGSLKLNDQARTAWRNYDKFHYEHVKHVLSLYGPV
                     FEF"
     gene            16196..16738
                     /locus_tag="VVO77_000270"
     CDS             16196..16738
                     /locus_tag="VVO77_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEU5692346.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGELDLAESVSDNILLNIPIKVLTAEEEAGQGFISGNDWQIMTEEEYQAQKA
                     VKKEENSPFAGLQGLFDGDE"
     gene            16738..17367
                     /gene="nth"
                     /locus_tag="VVO77_000271"
     CDS             16738..17367
                     /gene="nth"
                     /locus_tag="VVO77_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEU5692347.1"
                     /translation="MVLSKKRARKVLEEIITLFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            17578..18099
                     /gene="pyrR"
                     /locus_tag="VVO77_000272"
     CDS             17578..18099
                     /gene="pyrR"
                     /locus_tag="VVO77_000272"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEU5692348.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            18118..19041
                     /locus_tag="VVO77_000273"
     CDS             18118..19041
                     /locus_tag="VVO77_000273"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEU5692349.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            19091..20170
                     /gene="carA"
                     /locus_tag="VVO77_000274"
     CDS             19091..20170
                     /gene="carA"
                     /locus_tag="VVO77_000274"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEU5692350.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            20483..23659
                     /gene="carB"
                     /locus_tag="VVO77_000275"
     CDS             20483..23659
                     /gene="carB"
                     /locus_tag="VVO77_000275"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEU5692351.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKDVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(23934..24743)
                     /locus_tag="VVO77_000276"
     CDS             complement(23934..24743)
                     /locus_tag="VVO77_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU5692352.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(24745..25548)
                     /locus_tag="VVO77_000277"
     CDS             complement(24745..25548)
                     /locus_tag="VVO77_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU5692353.1"
                     /translation="MKQLTVEDAKQIELEILNYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(25558..27045)
                     /gene="tacF"
                     /locus_tag="VVO77_000278"
     CDS             complement(25558..27045)
                     /gene="tacF"
                     /locus_tag="VVO77_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEU5692354.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFMYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            27381..28088
                     /locus_tag="VVO77_000279"
     CDS             27381..28088
                     /locus_tag="VVO77_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEU5692355.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLHKERIIITKGGADRNTSIEKIIEAIDAYRPL
                     TSEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            28093..29115
                     /locus_tag="VVO77_000280"
     CDS             28093..29115
                     /locus_tag="VVO77_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEU5692356.1"
                     /translation="MINQIYQLTKPKFINVKYQEEVIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEDLAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFENAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            29132..30001
                     /gene="licA"
                     /locus_tag="VVO77_000281"
     CDS             29132..30001
                     /gene="licA"
                     /locus_tag="VVO77_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEU5692357.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIEFAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            29991..30869
                     /locus_tag="VVO77_000282"
     CDS             29991..30869
                     /locus_tag="VVO77_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEU5692358.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            30881..31570
                     /locus_tag="VVO77_000283"
     CDS             30881..31570
                     /locus_tag="VVO77_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEU5692359.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEIFKNEN"
     gene            31666..32514
                     /gene="dprA"
                     /locus_tag="VVO77_000284"
     CDS             31666..32514
                     /gene="dprA"
                     /locus_tag="VVO77_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEU5692360.1"
                     /translation="MKITNYEIYKLKKSSLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPDSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            33398..34441
                     /locus_tag="VVO77_000285"
     CDS             33398..34441
                     /locus_tag="VVO77_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HEU5692361.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            34608..36695
                     /gene="topA"
                     /locus_tag="VVO77_000286"
     CDS             34608..36695
                     /gene="topA"
                     /locus_tag="VVO77_000286"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEU5692362.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNNEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIARYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQNGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMAVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            36801..37160
                     /locus_tag="VVO77_000287"
     CDS             36801..37160
                     /locus_tag="VVO77_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEU5692363.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            37253..37885
                     /locus_tag="VVO77_000288"
     CDS             37253..37885
                     /locus_tag="VVO77_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEU5692364.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGTLTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            37929..38585
                     /locus_tag="VVO77_000289"
     CDS             37929..38585
                     /locus_tag="VVO77_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEU5692365.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            38604..39698
                     /locus_tag="VVO77_000290"
     CDS             38604..39698
                     /locus_tag="VVO77_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HEU5692366.1"
                     /translation="MNFQLAKYSLLKKFSENIGFTTPEEYGAIFKYLIENVKTDRQII
                     YSPHCHDDLGIAVANSLAAVKNGAGRVEETINGIRERAGNAALEEIAVALNIRQDYYQ
                     VETSIVLTETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKIPLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALVDKKQEITDADI
                     RALVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEFNATGQGSVEAIF
                     NAIDKFFNQSVRLVSYTIDAVTDGIDTQERVLVTVENRDTETILNAAGLDFDVLKASA
                     IAYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            39710..40736
                     /gene="leuB"
                     /locus_tag="VVO77_000291"
                     /pseudo
     CDS             39710..40736
                     /gene="leuB"
                     /locus_tag="VVO77_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
     gene            40733..41002
                     /locus_tag="VVO77_000292"
     CDS             40733..41002
                     /locus_tag="VVO77_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEU5692367.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIPEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            41006..41365
                     /gene="leuD"
                     /locus_tag="VVO77_000293"
     CDS             41006..41365
                     /gene="leuD"
                     /locus_tag="VVO77_000293"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEU5692368.1"
                     /translation="MVGSSREHAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSKWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            41527..42150
                     /locus_tag="VVO77_000294"
                     /pseudo
     CDS             41527..42150
                     /locus_tag="VVO77_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276310.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            42316..44247
                     /locus_tag="VVO77_000295"
     CDS             42316..44247
                     /locus_tag="VVO77_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HEU5692369.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYTEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFSHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQ
                     KDQAVADDNEGDENDDADY"
     gene            44234..45550
                     /locus_tag="VVO77_000296"
     CDS             44234..45550
                     /locus_tag="VVO77_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HEU5692370.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYQRFSHNDSHVKGV
                     IDVRNHLKKNLPFTGNIAYATREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASFYSTFCKMMENSEENFKAIIDEEVGRK"
     gene            45725..46711
                     /locus_tag="VVO77_000297"
     CDS             45725..46711
                     /locus_tag="VVO77_000297"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEU5692371.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHNQGLIASISVGVKDYEY
                     DFVSQLKADTPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            46775..46846
                     /locus_tag="VVO77_000298"
     tRNA            46775..46846
                     /locus_tag="VVO77_000298"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:46808..46810,aa:Arg,seq:ccg)
     gene            47029..47727
                     /locus_tag="VVO77_000299"
     CDS             47029..47727
                     /locus_tag="VVO77_000299"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEU5692372.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            47718..51257
                     /gene="smc"
                     /locus_tag="VVO77_000300"
     CDS             47718..51257
                     /gene="smc"
                     /locus_tag="VVO77_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEU5692373.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENACKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDNLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDMHYQTALEIALGASSQHIIVEDENAATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDAIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHAREAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIVIKPELEQLQK
                     EIAADEASLGSEEAALKTLQDQMAALTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKEKCQESLATIASEKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEEVAQARLLKTELQGQKRYEVADIERLGKELDNLNIEQEEIQRMLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQNQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNLEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            51254..52048
                     /locus_tag="VVO77_000301"
     CDS             51254..52048
                     /locus_tag="VVO77_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU5692374.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFADVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNEHVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            52048..52866
                     /locus_tag="VVO77_000302"
     CDS             52048..52866
                     /locus_tag="VVO77_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU5692375.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGHEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVSEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            52870..54147
                     /gene="ftsY"
                     /locus_tag="VVO77_000303"
     CDS             52870..54147
                     /gene="ftsY"
                     /locus_tag="VVO77_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEU5692376.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAEVEIVEQAVFQEEEIQDTVEESLDLEPVVEVSQKEVEEFPHSEEGNTEFLETIE
                     ENNSEVLEAERPQAEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEEL
                     LIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQ
                     DNLTVMLFVGVNGVGKTTSIGKLAHRYKRAGKKVMLVAADTFRAGAVAQLAEWGRRVD
                     VPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGRIIKR
                     VVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREEL
                     NIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(54191..55678)
                     /locus_tag="VVO77_000304"
     CDS             complement(54191..55678)
                     /locus_tag="VVO77_000304"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEU5692377.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATANKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEELWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFDAKWTWQPDIAYRQDGRFE"
     gene            complement(55827..56567)
                     /locus_tag="VVO77_000305"
     CDS             complement(55827..56567)
                     /locus_tag="VVO77_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU5692378.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(56567..58732)
                     /locus_tag="VVO77_000306"
     CDS             complement(56567..58732)
                     /locus_tag="VVO77_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEU5692379.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            58905..59858
                     /locus_tag="VVO77_000307"
     CDS             58905..59858
                     /locus_tag="VVO77_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU5692380.1"
                     /translation="MKNKRIFKDFQASKMNLNIYTSPLLAFVFVFIGEFVAYTLYGIS
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            59935..61923
                     /gene="uvrB"
                     /locus_tag="VVO77_000308"
     CDS             59935..61923
                     /gene="uvrB"
                     /locus_tag="VVO77_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEU5692381.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            61933..62496
                     /locus_tag="VVO77_000309"
     CDS             61933..62496
                     /locus_tag="VVO77_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU5692382.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKMNDGYYQINGNS"
     gene            62462..62971
                     /locus_tag="VVO77_000310"
     CDS             62462..62971
                     /locus_tag="VVO77_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU5692383.1"
                     /translation="MTVIIKSMETPEEIEGKSLVHWQTWREAYDDLLPAEFQETMTLE
                     RCRFFSQKYPENTLIAIGDLKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SKIILKSRS"
     gene            63024..63491
                     /locus_tag="VVO77_000311"
     CDS             63024..63491
                     /locus_tag="VVO77_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU5692384.1"
                     /translation="MSRSQLTILTNICLIEDLETQCVVMQYRAPETNRWSGYAFPGGH
                     VENGEAFAESVIREIYEETGLTIQNPQLVGVKNWPLDTGGRYIVFCYKATEFTGTLQS
                     SDEGEVSWVQKDQIPNLNLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(63488..64003)
                     /locus_tag="VVO77_000312"
     CDS             complement(63488..64003)
                     /locus_tag="VVO77_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEU5692385.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHQVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(64015..64542)
                     /locus_tag="VVO77_000313"
     CDS             complement(64015..64542)
                     /locus_tag="VVO77_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU5692386.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(64824..65387)
                     /locus_tag="VVO77_000314"
     CDS             complement(64824..65387)
                     /locus_tag="VVO77_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU5692387.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(65371..65922)
                     /gene="coaC"
                     /locus_tag="VVO77_000315"
     CDS             complement(65371..65922)
                     /gene="coaC"
                     /locus_tag="VVO77_000315"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEU5692388.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETLDEKTL"
     gene            complement(65934..66623)
                     /gene="coaB"
                     /locus_tag="VVO77_000316"
     CDS             complement(65934..66623)
                     /gene="coaB"
                     /locus_tag="VVO77_000316"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEU5692389.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLFAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISAGQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            66853..68523
                     /locus_tag="VVO77_000317"
     CDS             66853..68523
                     /locus_tag="VVO77_000317"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEU5692390.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELEIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAAL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            68851..70026
                     /gene="mutY"
                     /locus_tag="VVO77_000318"
     CDS             68851..70026
                     /gene="mutY"
                     /locus_tag="VVO77_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEU5692391.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            70081..70785
                     /locus_tag="VVO77_000319"
     CDS             70081..70785
                     /locus_tag="VVO77_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU5692392.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            70778..72127
                     /gene="vicK"
                     /locus_tag="VVO77_000320"
     CDS             70778..72127
                     /gene="vicK"
                     /locus_tag="VVO77_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEU5692393.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            72129..72938
                     /locus_tag="VVO77_000321"
     CDS             72129..72938
                     /locus_tag="VVO77_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEU5692394.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            73029..73271
                     /locus_tag="VVO77_000322"
     CDS             73029..73271
                     /locus_tag="VVO77_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEU5692395.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            73273..73527
                     /locus_tag="VVO77_000323"
     CDS             73273..73527
                     /locus_tag="VVO77_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEU5692396.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEGPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            73574..74269
                     /locus_tag="VVO77_000324"
     CDS             73574..74269
                     /locus_tag="VVO77_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HEU5692397.1"
                     /translation="MKKKWLFADYYDTTIILLALISVILVLLGFAEMTDLDNPPYSII
                     DLVIWGVFVIDYSWRFFITKRKWRFILENIFDLLTILPLNAIFTVFRLGRIFRLARLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPVSLFGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLKDELSS"
     gene            complement(74618..75604)
                     /locus_tag="VVO77_000325"
     CDS             complement(74618..75604)
                     /locus_tag="VVO77_000325"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEU5692398.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            75798..78266
                     /gene="gyrA"
                     /locus_tag="VVO77_000326"
     CDS             75798..78266
                     /gene="gyrA"
                     /locus_tag="VVO77_000326"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEU5692399.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQILSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLTEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            78266..79009
                     /gene="srtA"
                     /locus_tag="VVO77_000327"
     CDS             78266..79009
                     /gene="srtA"
                     /locus_tag="VVO77_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEU5692400.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
BASE COUNT        24048 a        14190 c        17438 g        23385 t
ORIGIN      
        1 ccacgtccag aacatcctag gaaagcagac gctcaaacca ttgtcgcgtc taaaaataaa
       61 atctcaattc aagaagaaaa gaaagcgctt taaaaccagt agaccttttc ataaggttcg
      121 cttgatgtac caaatagtac gcccatgcaa aagaatatct attttgttgt cttggacctg
      181 catacgacgg atagagataa aattatccag ctattcaagg attggacgga ttatagtgcc
      241 aagttggtcg agggggaatt ggttaaaaaa gatggacaga atgctctctt tcctccgagc
      301 gatactggtg agacagttgg gctcaatcct catcgtttga cgctgacttt tggtgtatct
      361 gcaagtttct tgaaaaggat gaacttggaa aacaagcgcc ctcgactgtt cagggattta
      421 cctctatttc ctaaggagca attacgtgaa aaatatactg gtggagatat tgtgattcat
      481 gcttgtgcag atgatgagca aattgccttt cacgctattc gcaatctcat ccgtaagggg
      541 agaaatgcgg tgccccttcg ttggagtcag tctggatttg cagctatcgg ggatcgaatg
      601 gagactccgt ggaacctctt tggttttaag gatggaacag caaatccaac caaggagcaa
      661 gactttgacc gcgttatctg ggctgatagt aaggactgga tggaaaatgg ttcttatatg
      721 gcagttcgtc ggattcagat gtttttagag acctgggacc gcactagtct cgaagaacga
      781 gaaaatacct ttggtcgtta caaggaaagc ggtgccccct ttggtaagaa aaatgagttt
      841 gatgaagtgg atttgagtct cttacctgat gattcgcatg tttgtttggc caaagaagtg
      901 gataagccac ttttacgtcg ttcttattct tactcagatg gcattgatga aaagactggt
      961 cagtttgata cgggattgct cttcatttct ttccagaagg atcctgataa ctttgttaag
     1021 gttcaaacta acctaggtgc tactgataag atgaatgaat acatcactca cataggtagt
     1081 ggacttttta cttgctttgg tggtgtggag aaaggaggct acattggtca gaaattattg
     1141 gaaggctaaa agctggttac tagttttagc tttgtcattt ttaattcttt ccccagcagg
     1201 tgcccaagaa agcttgagtt ttttctttgt gaaaatcaca gatgcatcca aaacggttaa
     1261 aaatggtggt cagactgaga cccagaaact cgttacgaag atggcatcag acttcgaaag
     1321 agtagaaaat aaggattctg aggttggtaa gattgttaag gaaaagttag ctctatctgg
     1381 agatattact gaagccaaac tcaccgaaat ttcctcagct ctattagctt ttgaaaaaga
     1441 acaaaatcct gttgacctag atgcggaaaa ggaaaaattg gtaaaccgtc taagtcctcg
     1501 ttttgaaacc ttagagcagg ccattgcctc caaagatttg gaaaaagtcc gagaagcttt
     1561 taagaaaatg aattccactt ggaccatcaa tgaaagtgtg gttcgtgaca atagtatagc
     1621 tcattatgga cgtgttgaaa cagctatttc cttcctgcct agtagcatgg aaatcgaacc
     1681 tacagatgag tctggaacat gaaaacagca gttgatttca agaaacaaaa aagaacagcc
     1741 aaaactgttc tcttatcatt atttgagacc gtattttttg ttgaaacgat ccacgcgtcc
     1801 atctgcttga gtgaactttt gacgtccagt gtagaatggg tgtgagtctg atgaaatttc
     1861 cacacggatc aatgggtaag tttcgccttc gaactcaact gtttcgttag agcgttttgt
     1921 tgaaccgcta aggaattggt aaccagtagt tgtgtccatg aagacaactg ggcgatattc
     1981 tggatggata tcttttttca ttttgcaata tttcctttct gccatggtct ctttgcgagc
     2041 catagattgt tactatacta gtctatcaga ttctgaaaag tttggcaagt attttatcag
     2101 tttttaagca agttttttaa cttttggtag atgatttcgt tttcttctag gctataggaa
     2161 ttagcaccac ttgctagagg gtggcctcca ccatcatgct ccttggcaat ttcattgata
     2221 ggatggactt tactgcgtaa gcgaactcgg tagtggccat cagcctgttc gacaaaaatt
     2281 ccccagagac tcactctgtc aatgcgtcca ggtgcaccta caatggccgc agtttcagca
     2341 tcggttatat tgtattgttt caagattttc tgactcagga taacgcgagc agcaccattt
     2401 tcatccactt ccagatggtc gtagatgtag ccttgcagtt tagcaatttt gtagctcata
     2461 gtgtccattt tgcgagtgag agccgcaaag tcaaagttat gttctctcaa ataagcagcc
     2521 aggcgaagag tccgtgcagt ggtagaaggg tagaggaagc gacctgtatc accgacaatt
     2581 cctgcaaaga gcaactcagc atcgcgatct gccaaggcta gttgggttgt ttgggcaaat
     2641 agggtaatca tctcgctagc gctacttgaa ctagtatcga cccaagacag gtcaccgtat
     2701 acatcatcat ttggatggtg gtcaatctta atgagaaaat caccttgact atagcgctta
     2761 tcatcgatac gagcagtatt agctgtatca cagacgatga caagtgcgcc ttggtaggct
     2821 ctatcttcaa caagatccat ctcagccatc caagtaagag ttggttcatc aaaaccgacg
     2881 gctttgatgg ttttttctgg gaaatgatgt tccagcaagg ctttcaatcc cacctgactt
     2941 cccaaggcat cagggtctgg tttcatatga cgatgaatga taatggtgtc gtattcttta
     3001 attttttcta aaatttgttg gcaaatctcc ataaataacc tcaattcttt ctcatttcat
     3061 tgtagcacaa gaatttttat ttttaaaatg aaaaagatgt gatataatgg agaaagataa
     3121 attgaggagg acgatatggc attagcaaaa attgtatttg ccagtatgac cggtaatacc
     3181 gaagaaattg cagatattgt agcagacaaa ttacgtgact tgggcttgga tgttgatgtt
     3241 gatgaatgta caactgttga cgcttcagac ttcttggaag cagacatcgc tatcgttgcg
     3301 acctatactt atggtgatgg tgaattgcca gatgagatga tggacttcta cgaagaccta
     3361 gcagatctca acttgaatgg caaaatctac ggagtggtcg gctcaggaga taccttctac
     3421 gatgaattct gtaaggctgt tgatgacttt gaccgtgtct ttgtgtcaac aggagcagaa
     3481 aaaggttcag agtgtgttaa agttgatctt tctgccgagg aagaagatat tgaacgcttg
     3541 gaacaattcg cagaagaatt ggctgctaaa gtaggataaa cataaaagtg cgctgatgta
     3601 atcaatcagt gcatttttct tatcgagagt tgggatttta ctagcctaat tgatggcttt
     3661 ttgatacaat aattcaaata aaggaggaga ctgtatggat ttagatatta ttcgtcaaga
     3721 aatcgatcaa atcgacgacc aaattgtcaa actgttagaa gaacgaatgc atttagttga
     3781 gggggtggtt gcttataaga aagcttcagg taaaccgatt ttagatacta agagagaaga
     3841 agttattttt gaaaaggtta ggagtcgtgt agaggacaag cgctatcagg agactattgt
     3901 cgcgactttt tcggacatac tcaaacgttc gcgtgattat caggatcaaa atatcaaatg
     3961 aaaaaagaac aattttatcc gctaggaatt tttctagctg ctatgttggg cggacttgtc
     4021 cgatatctag tttccacctg gttaccagcc agtccagact ttccttgggg cactctcttt
     4081 gtcaactatc tgggaatttt ctgcttgatt tttcttgtca agggctatct ggtctataag
     4141 gggactagta agggcttgat tttagcactg gggacgggtt tttgcggagg tttaacaact
     4201 ttttccagcc taatgcttga tactgtgaag ctgcttgata cagggcgtta tcttagttta
     4261 gtcctgtatt tgcttttgag catcggtgga ggcctactct tagcttattt tctagggagg
     4321 aagaaatggt aatcgtctat cttgcaattg cttgtggttt cggagcactc gtacggtatt
     4381 tcttttctcg ctataatcaa gcttctaaat tgccactcgg aacgctcata gctaatcttt
     4441 taggttgttt tttaattgga gtattctaca atcatgtaga gtctaaggaa gtatatgcta
     4501 ttctagcaac aggattttgt ggcggtttaa caactttttc gaccttgaat gacgaacttc
     4561 aaagactgct aagtgataag aaggtctttt attcttacct gactttgact tacataggtg
     4621 gtttggttgc gattttttta ggaattttgc tataaatttc tttacttttt tttagaaatt
     4681 tggtaaacta tatcttgtgt gtaatggacg cacaaaaata cagtttatcc gctgaggaag
     4741 attcctcaag attgacaaag ataggagaat aaaatgaatc cattaatcca aagcttgact
     4801 gaaggtcaac ttcgtacaga tatcccatca ttccgtcctg gtgacactgt tcgtgtacac
     4861 gcgaaagttg tcgaaggtaa ccgtgaacgt atccagattt ttgaaggtgt tgttatcgca
     4921 cgtaaaggtg ctggaatctc agaaaactac acagttcgta aaatctctaa cggtgtaggt
     4981 gttgagcgta tcttcccaat ccacactcca cgtgttgaaa aaatcgaagt tgttcgttac
     5041 ggtaaagtac gtcgtgcgaa attgtactac ttgcgtgctc ttcaaggtaa agcagctcgt
     5101 atcaaagaaa tccgtcgtta attcgactaa aaaactctgc ttttcagcag agtttttatc
     5161 tagctccctt agttcaatgg atataacaac tccctcctaa ggagtagttg caggttcgat
     5221 tcctgcaggg ggcagtaatt agacatcaaa aaccgctcag ctgagcggtt tttatctatt
     5281 ctttcctttt acagtaccaa tgtacgaata gcatgggcaa cgccggattc gtcatttgtt
     5341 ttggtgatgt atttggcgat ttttttgatt tctggatttc cgttttccat gactacaggg
     5401 ttgccaacga cttccagcat ggcacggtca ttttcttcgt ctccgatagc catggtttca
     5461 tctttggtta atcctagttt ttcagctaag tgagtaatag ctgaaccctt gtctacattc
     5521 tttttaagga gttcgaggta gaaaggagca gatttgttga tagagtagtg ctcgtaaaat
     5581 tcggctggta ttttttcaat cgcagcatcg aggatttctg gttcatcgat gaacatacac
     5641 ttgacaattt ccttgccagc catttcttca ggagtgcggt agaagatagg catgctgacg
     5701 agggttgatt cgtgcacagt gtatgttccg atattgcgat tggcggtata gataccgtcc
     5761 ttagtaatag catgcatgtg aacaccaagc ttgcgactga gaaattccat atccagataa
     5821 tcctcatagg tcaaggattc gctgataatc tcatggccag tatcagtctc ttggacaagg
     5881 gcaccattga aggtcaccac atagtcacct tggtctctca actgcaagtc gtccagaagt
     5941 ttggcaacac ctgcgatggg gcggccagtt gcaatcacga ctttgacacc agcttctttg
     6001 gcatcttgga tggcagaaaa gacttcagga gtgatttcct tttggctgtt gactagggtt
     6061 ccgtcaatat cgacggcaat tagtttaata ctcataaaat tcctcttcta gtttttattt
     6121 ggggtaaaat gatcgttctc aatcaagtgt aaaaattgct gggtaatgct tgcaaagatg
     6181 ctgttttggt ccaacatttc ttttggaaaa taaaagcgat tatctccgtg gcgactgcca
     6241 gcaagggatt ggacgatagg agacaggcta gagagttcgg ccagttctcc atttttttgt
     6301 aaaatctcaa tctgtgtccg tgggttttca gattcgggac gatagatatc ataagggagg
     6361 tcaaagttct tatgaatggc agtgtagtag tcgggatcaa agccgatatc ctcaaccaat
     6421 tttctcatgc tagtaagttg atcttggtcc tcttgtgaaa aggtaatgga tttaaagacc
     6481 ttgcggttga caaagcgatg cgataaatct gcaagaatct tgtcaggact ggtcatccaa
     6541 agctggaagt aggtattcat cacgccatca tccagagcca gatagtcagt caaggtcaca
     6601 tttttttcga agaaaggcag gaggtgtgga gaagttcggg caaagaaatc cttgtcctca
     6661 ggatagagtt ccttggcgcg tttgagaaga ttctgtagga gaacttccat ggcgcgtgtt
     6721 gcggggtgga aataaacctg catgtacatc tggtagcgac tgaggacgta gtcttcgatg
     6781 gcgtgcatgc cattgcgctg aaaggcgata ccattttcga taggacgaat gactcggagg
     6841 attcgagtca ggtcaaattc cccataggat gctcctgtaa aataggagtc acgcaagaga
     6901 tagtccatgc ggtccgcatc aatctggcta gaaatgagct gcacgacctg cttattagga
     6961 taggtatggt caatgacact ggccaccttt tctgggaaat caggtgccac ttgtagcagg
     7021 acttggtgaa tctctgtctc aggattttga ataatctcct gagtaatggc ttcatggtct
     7081 gtatcaaaga gattttcaaa agtatgggag taggcaccat gcccaaggtc gtgtaggaga
     7141 gcagcggtca tggtcaagag agactcggca ggattccatt cctcaggata tttttcttcg
     7201 aaaatctctg tgatgcgtcg tgcaatttca tagactccta gacagtgaga gaagcgacta
     7261 tgctctccac cgtggaaggt ataactggaa gttcccagtt gtttgatccg gcgcaaacgt
     7321 tgaaattctt ttgtattaat caagtcatag atgatttgat tattgacatg gatgtagttg
     7381 tgaacagggt cacggaatac tttttcgttc atatgaccat tatagcaaaa tcctgctctt
     7441 tttggtaaaa tagtaggaca agagacaaga aagagggcct gatgtgaaga ttcggatgcg
     7501 aaatacaatt cagtttgatg agcagttgga agtgattgac cagctttatg atgtggaagt
     7561 gcatgaaaaa ggagattata gctacctgct tttctataat gaggaaaagg aaaaagtagt
     7621 gattaaattt catggtcaag aacttgtgat gagtcgattt tccaatccca agaccattat
     7681 gcgctttcta aaggatagtg atagtttagc ctatattccc acacctatgg gtatgcagga
     7741 gtttattatc caaacgaatc gttatcaagt ggatgggcaa aagattgaac tagattatca
     7801 actacaaaat caagagggac atccctttgc cagctatcaa ttggaaatta cttggggcta
     7861 ggctcatgtc tttttcaaat ttagctatct atcttcttgg atcggcttcc tagtgtggta
     7921 gattaggcta atttttggta taataaaagt tatggaaatc gaaaaaacca atcgtatgaa
     7981 tgcgctcttt gaattttatg cggcgctttt gacagataag caaatgaatt atatcgagct
     8041 ctactacgct gatgattaca gccttgctga aattgccgag gagttcggtg tcagtcgtca
     8101 ggctgtctat gacaatatca agcgaacaga aaagattctg gaagattatg agatgaaatt
     8161 gcacatgtac tcggactata ttgtccgcag tcagattttt gatcagattt tggagcgcta
     8221 tcccaaggat gactttctgc aggagcagat agaaatttta acaagcattg ataatagaga
     8281 ataagaggaa gaaaaatggc atttgaaagt ttaacagaac gtttgcagaa cgtctttaaa
     8341 aatctacgta aaaaaggaaa aatctctgaa tctgatgtcc aagaggcaac caaagaaatt
     8401 cgcttggcct tgctcgaggc cgacgttgcc ttgcctgttg taaaggactt tatcaagaaa
     8461 gttcgtgagc gtgcagtcgg gcatgaggtc attgatacgc ttaatcctgc gcaacagatt
     8521 attaaaatcg ttgatgagga actgacagcc gttttaggtt ctgatacggc agaaattatc
     8581 aagtcaccta agattccaac catcatcatg atggttggtt tacaaggggc tggtaaaaca
     8641 acctttgctg gtaaattggc caacaaactc aagaaagaag aaaatgctcg tcctttgatg
     8701 attgcggcgg atatttatcg tccagctgcc attgaccagc ttaagacctt gggacaacag
     8761 attgatgtgc ctgtctttgc acttggaaca gaagtaccag ctgttgagat tgtacgtcaa
     8821 ggtttggagc aagcccaaac taatcataac gactatgtct tgattgatac tgcgggtcgt
     8881 ttgcagattg atgagctcct catgaatgag cttcgtgatg tgaaagtatt ggctcaacca
     8941 aatgaaatct tgcttgtcgt tgatgctatg attggtcagg aagcagccaa tgttgcgcgt
     9001 gagtttaatg ctcagttgga agtgactggg gtcatcctta ccaagattga tggtgatact
     9061 cgtggtggtg ctgctctgtc tgttcgtcac atcactggaa aaccaatcaa gttcactggt
     9121 acaggtgaaa aaattacaga tatcgaaacc ttccacccag accgtatgtc tagccgtatc
     9181 cttggcatgg gggatatgct cactttgatt gagaaagctt ctcaggaata cgatgaacaa
     9241 aaagcccttg aaatggctga gaagatgcgc gaaaacacct ttgattttaa tgatttcatc
     9301 gatcaattag atcaggtgca aaatatgggg ccgatggaag acttgctcaa gatgattcca
     9361 ggtatggcca acaatccagc ccttcaaaac atgaaggtgg atgaacgcca gattgctcgt
     9421 aaacgtgcca ttgtgtcttc gatgacacct gaagagcgtg aaaacccaga tttgttaaat
     9481 ccaagccgtc gccgtcgtat tgctgctggt tctggaaata cattcgtcga agtcaataaa
     9541 ttcatcaagg actttaacca ggctaaacag ctcatgcagg gtgttatgtc tggggatatg
     9601 aataaaatga tgaagcaaat ggggattaat ccaaataacc ttcctaaaaa tatgccaaat
     9661 atgggaggaa tggatatgtc tgcccttgaa ggaatgatgg gacaaggcgg tatgcctgac
     9721 ttatcagctc tcggaggagc aggaatgcca gatatgagcc agatgtttgg tggcggtttg
     9781 aaaggtaaaa ttggtgaatt tgccatgaaa cagtccatga aacgtatggc taacaaaatg
     9841 aagaaagcga agaagaaacg caagtaagac aagagattga tgcaaatctc atttgatgag
     9901 aaaataaagt aaaaatttct atgataaaac gtacagtatc aaggttttag aatatctgat
     9961 attatacgtt ttttgatttt aataattttg ttaagacact tttattatgg tatacgaaaa
    10021 atccactcag ctgtctgagt ggattaggtg tatttagact cttagtcttt attttcgtat
    10081 ggcaagatca agttcaagat gattcctgtc atggctgaaa gggcagtacc tgaaagtgta
    10141 actggaccaa gtttaaggat agctcctcca agtccaagaa ccaacatagc acttgcgatg
    10201 atgaggtttc gcatttgagc gaaatcaaca cgttctttaa tcaagacttt caaaccattg
    10261 ctggcgataa ccccatagag aaggattgac ataccaccaa gtacagcgtt tggaatagtt
    10321 gaaatcaagg cagtgaattt accaaggaag ctgagggcaa tcgcgatgaa ggcagcgtta
    10381 cggataactg agacagaagc gatacgagtc ataccgataa cccctgtatt ttctccgtaa
    10441 gttgtattgg ctggtccacc aaggaaggca gaaacagaag ttgcgatacc gtcaccaaga
    10501 agagtacggt gaagacctgg ttcttttaag aattgacgac cacagatttg acccaaaaca
    10561 gtatggtctc cgatatgttc agaaattgtt acgatagcga ttggcaagat agcgatggct
    10621 tctggaccaa agtaaagatt gtactcttta aaggcaccac ctgtgctaaa tggcaagtag
    10681 aaaccaggaa tttcaaacca gttagcttct aggacaggcg taaagtcaac caaaccaaga
    10741 gttagtgcga agaggtaacc accgataatg gcaaagagga atggaatgat tcgtaggaag
    10801 ccttttcctt ttgtattgat aaaggcagca attaggaaag taacaacggc taccagagca
    10861 tttttccaat ttccgtctgc tacaagacct gcattggtaa cagctgaacc tgcaagtcca
    10921 agaccgataa cgatgatcat aggaccgata atgattggtg gcaagagttt atcaatccat
    10981 tttgttccta caaatcggat gctggtagca acaaggacat agaccaaacc agtcaagata
    11041 acccctgttt gagcagcaga tacatccccc cccatttctt tcatagccag tgacatagct
    11101 gtgataaagg cgaatgaaga acctagataa actggaactt taaaaccagt agcaagcatg
    11161 tagatgagtg ttccaacacc tgaagcaaaa agggcaacag atacaggcat tcccaaaatc
    11221 aatggtacca agatggtcgc accaaacatg gcgaaaacgt gttggaaact aaggagaatt
    11281 ccttttccag ccgaaggacg ttggtcaacg tctagtaaca aatcaacagt tgattcttgt
    11341 ttcatataaa cctcactttt gggcatcaaa aaagagccca ttattttaca gcaataggcc
    11401 ctcagagtaa gacttcttta aaatttagat tttaaagagt tttaaatatt tctgcgtctt
    11461 cgtcacctca cgggatgaca ttaaaaacct ttgcttagga tagtatagca gaaaaaaatg
    11521 attttgtaaa tcattttttc ccgagcctag aaataaaaga gcgaggctga ttttgtaaac
    11581 atttgtttac taaaaaattt aaagtgggcg tttatttggc ataccagcct tacgtggata
    11641 tttatttggt gtttcttttt tcttttctac cactgtgata tagcgcggat ctctattcgg
    11701 tagggcgtag ctgagattgt cttcgacctt actaaaaagg agattgaggg cattcttagc
    11761 ttctaataat tcctcaggcg cattgctggc cttgagtgcc aatagttttc caccaacctt
    11821 aaggtaggga atggtcaatt cagataggac ctgcatacgg gcaaccgcac gagctgttac
    11881 aaaatcatat tgagcacgga agttcttgtc ttgggcaaaa tcttcggcac gtccgtggta
    11941 gaaatgaact ccgttcaaat ccagttcttg agccaagagt tgtaggaagt tgatgcgctt
    12001 attgagtgaa tcaataatgg tcacatctaa ctccggatag agaattttca ttggtagact
    12061 aggaaatcct gccccagccc cgatatcaag aagtttgata gtttcattgg gaatcaaacc
    12121 ttgaagaatg ggtgcaatcg aatcgtaaaa atgtttgaga taaacttctt ccttgtccgt
    12181 aatcgccgtc aaattaatct tctcattcca ctcgaccaag agctcaaaat aacgttcaaa
    12241 ttgttctttt tgctggtccg aaagtggaag attctgctcg gcaagcaagt tgtaaaatgt
    12301 ttttggtttc atagttattt ccttctttag tatcatctta ttttaccaca atcatagaaa
    12361 atttgatata ctggtactaa tctaaaagca gaaaggactt atattatgac ttggattatt
    12421 cttggagtta tcgctcttat tgttattttt gtgattgtta gctataacgg tttggttaaa
    12481 aatcgtatgc aaaccaagga ggcttggagt cagattgatg ttcagttgaa acgtcgaaat
    12541 gacctcttgc cgaacttgat tgagactgta aaaggttatg ccaaatatga aggttctacc
    12601 cttgaaaagg tggcagaact acgtaaccaa gtggcggcag cgacttcacc agcagaagct
    12661 atgaaagcca gtgatgccct cactcgtcag gtttcaggta tttttgcagt tgcagaaagc
    12721 tatccagatt tgaaagctag tgctaacttt gttaaattgc aagaggagtt gacaaacaca
    12781 gaaaataaaa tttcttactc tcgtcaactc tataacagtg ttgtcagcaa ctacaatgta
    12841 aaattagaaa ctttcccgag caatattatc gctggaatgt ttggatttaa agcggcagat
    12901 ttccttcaaa cacctgaaga ggaaaagtcg gttcctaaag ttgattttag cggtttaggt
    12961 gactaagatg ttgtttgatc aaattgcaag caataaacga aaaacctgga ttttgttgct
    13021 ggtatttttc ctactcttag ctcttgttgg ttatgcggtt ggttatctct ttataagatc
    13081 tggacttggt ggtttggtta tcgcactgat tatcggcttt atctacgctt tgtctatgat
    13141 ttttcaatcg acagagattg tcatgtccat gaatggagcg cgtgaggtgg atgagcaaac
    13201 ggcaccagac ctctaccatg tagtggaaga tatggctctg gtcgctcaga ttcctatgcc
    13261 ccgtgttttc atcattgatg atccagcctt aaatgccttt gcgacaggtt ctaatcctca
    13321 aaatgcggct gttgctgcga cttcaggtct actagctatc atgaatcgtg aagaactaga
    13381 agctgttatg ggacatgaag tcagtcatat tcgtaattat gatatccgta tttcgactat
    13441 tgcagttgcc cttgctagtg ctatcaccat gctttctggt atggcaggtc gtatgatgtg
    13501 gtggggtgga gcaggtcgca gacgaagtga tgatgaccga gatggaaatg gtcttgaaat
    13561 cattatgcta gtggtttccc tactagctat tgtactggca cctctcgctg caaccttggt
    13621 tcagctcgct atttctcgtc agagggaatt tctggcagat gcatctagtg ttgagctgac
    13681 tcgcaatccc cagggaatga ttaatgccct agataagttg gacaatagca aaccgatgag
    13741 tcgccacgtc gatgatgcta gcagtgctct ttatatcaat gatcccaaga aaggtggggg
    13801 gttccaaaaa ctcttttata cccacccacc tatctcagaa cggattgaac gtttaaaaca
    13861 gatgtaaaag aatccagagg tcgtctctgg atttttgcta tgttgcaaat ttataaatct
    13921 tctaaattaa ctagcttcaa accgtgttct gtcatgcgat agatgatcga gcagacttct
    13981 tttaagaaac gacggtcatg cgaaacagtg atgagaccgc ctggataggt tgcaaagagt
    14041 tttctgattt ggggttgaga agtgggagaa aagtttcgtg tgggttcatc cagcaggaga
    14101 aagtttggtt tgcgcaggac tagatccaaa agcaggagtt ttccctgttg tccgccagat
    14161 aaggagcgaa tttgatgctg catttctgga taactgaaat tgagactggc taggtgagag
    14221 tggattttct gaagttcctc tttttcccca gttttgctga tataagctat tggtgataaa
    14281 tccaattgta gttttttgtg gtaatcttgt ggcataaaac caagggaaat ctctctttta
    14341 tcattcagaa gttgctttaa tttggctaac agagttgatt tcccaacacc atttggcccg
    14401 ataataccga ttttttcttg cccacggaca gttagttgta gtttttgaac caaaactcgg
    14461 tcgtcaatgg acaaattttc tttttccagt tggactaaga ctttagaagc tggtaatggt
    14521 tggatgtctg aaaagaaaag ttggatttgt tcctcttcaa gtggtttttg agtcatggac
    14581 tgagctgcct tttcgtagcg tttttcttgt gagaggacag ttttcatctt tttagacaat
    14641 aggcgaccgg cagtactatc tttggtagct cgaagcgcag tttctacatt ttgcttaact
    14701 ctccgatgtt tttccatggt tttatcgtag gctctttggt tgttagcagc ttgctgactt
    14761 tgtttggcaa aattagcctt tctctgctca ctatagctat catagtctaa atgctctact
    14821 agcgtttccg cttctttacg gtgtttgacc agtcgcaagt gaacaatagt gtctgccgtt
    14881 tcagaaagaa agtcttcatc atgggaaatg aaaataacgg tttgcctggt cttttgaatc
    14941 tggcctttta gccaatcaac tgtctcaagg tctaggtcat ttgaaggttc atctaaaaat
    15001 agaatctcaa agggtttggc taactcatgg ataagctgaa ttttcaaagc ttctccccct
    15061 gatagattgc caatctcttg gtcacttgcg aaacgattgc tatcaaaatg caattcctcc
    15121 gccaaacgat agaggatact gtagtctaaa tcaatagaat ctaaaaagaa gtagtcgtgt
    15181 aaagttttct ttttcagctc ctcgggaagt ttttgaggaa tgtaggccag tgactgatag
    15241 tcagattgga tgtttccctt gatagtgaaa tcagacaaag cttcccccat taaaatttta
    15301 agtaaggttg atttgccatt tccttcttca ccaataatag caaccttttc cccgtcttgg
    15361 atggtcatgg ttaggtcaga tacaagatct cgtaaatctt tgttttgtgt gatggttaga
    15421 tgattgattt ttatcatatg atttcccttt ctagaatgtt catagtgcat aacaaaaagc
    15481 tctactttac ctagtagagc ccaaagtcta tgtcaaaaaa actctattaa catgccagaa
    15541 aaagagcata aaagagcaca caaaaagaga caaaaacaag atctactaaa taaaggttct
    15601 ttatttgata gacttagttg ttcatgtctc ccttacctcc gagtattagt atctttatat
    15661 tataccttta aggaaatttt gtcaacagaa aactggaaat tctatgctct aaaattcaaa
    15721 aacaggtcca tagagactta gtacgtgttt gacatgctcg taatggaatt tatcatagtt
    15781 tcgccaagca gtgcgtgctt gatcgtttag ttttaggcta cccagtccaa tcagaagact
    15841 ggtaggttgg taaaatttct caagatcaat taagatactg ttgttcaact gttccgtttt
    15901 tttgagctct tgcatagtag tgtttagcag ctcttgtagt cgaatatcat ctgccgtacc
    15961 ctgtttacag ttttggtagc ttttatttaa cttggatagg agttgaatga gtttcttgtc
    16021 ttccatgtga gcatcctcct tgatctgatg tactctttcc ctatagtata gcactaaaaa
    16081 ataaaactat aatagtaaat atgttaaaat tttgaatttt aattacaaag tttggtgtgc
    16141 tgatttgtag ccttttcatg gtataatcaa gagagtaaat ctttatggag gaagtatgaa
    16201 attaaatatt caagaaattc gtaagcagtc tgaaggtttg aactttgaac aaacgttaga
    16261 tttagttgat gacctgcgtg cacgtaatca agaaatttta gatgtaaaag atatccttgc
    16321 agttgggaaa gtacaatatg aagaccgtat gtatttctta gattatcaac tatcttatac
    16381 cattgttctt gcttcgagtc gcagtatgga gccagttgag ttagttgaat cttatccagt
    16441 cacggaagtt ttcatggaag gcgcaactaa ccagctagat caagaagttt tagatgatga
    16501 cttggtcttg cccatcgaaa atggggagct tgaccttgct gagagtgtat cagacaatat
    16561 cctgctaaac attcctatca aggtcttgac ggctgaagaa gaagctggtc aaggatttat
    16621 ctcaggaaat gactggcaaa tcatgacaga ggaagaatac caagctcaaa aagcagtaaa
    16681 gaaagaagaa aacagtcctt ttgctggctt acaaggacta tttgacggag atgaataatg
    16741 gtcttgtcaa aaaaacgagc acgaaaggtg ctagaagaaa tcattaccct cttcccagat
    16801 gccaagccta gtcttgattt taccaatcat tttgaactcc tggttgcggt catgttatca
    16861 gcccagacga cagatgcagc ggtaaataag gccacaccag gtctctttgt tgcctttcca
    16921 acaccccaag ctatgtctgt agcgacagag agtgagattg cttcacatat ttctcgcttg
    16981 ggattgtatc ggaataaagc taaattcctt aaaaaatgtg cccaacagtt actagacgat
    17041 tttgatggtc aagtccctca gacacgtgaa gaattggaga gtttggcagg tgttggtcgc
    17101 aagacagcca atgttgtcat gagtgtagga tttgggattc cagcctttgc agtggatact
    17161 catgtggagc gtatttgcaa acaccacgat attgtcaaaa aatcagcgac gccacttgag
    17221 gtggaaaagc gggtcatgga tatcttgccg cctgagcagt ggttagctgc ccatcaggcc
    17281 atgatttatt ttggaagagc catttgccat ccaaaaaatc cagagtgtga ccagtaccca
    17341 caattatatg attttagcaa tttgtaagat gctacattga aactttttgc ttgattttaa
    17401 gcatgctttg tgctatagta aatgataact aaatattcct ttaaacctgt cccgtgaggc
    17461 aggcaaggag cgcgataaag tagaagggtg aagtctatac tgtgtgcagt agggctcgct
    17521 tggctataaa tttcaagtct ccttgtttaa ggagactttt ctttttggag gtttgtcatg
    17581 aaaacaaaag aagttgtaga cgaattgacc gtcaaacgag cgattacgcg tattacttat
    17641 gagattatcg aacgcaacaa agatttgaat aagatcgtct tggctggtat taaaactcgt
    17701 ggtgtcttta ttgcccaccg aatccaagaa cgtttgaagc agttagaaaa tctttcagtt
    17761 cctgttgtgg aattggatac taaacctttc cgtgatgatg ttaaaagtgg agaagatact
    17821 tctttggttt ctgtcgatgt gacagaccgc gaagttatct tggtggatga tgtgctctat
    17881 acaggtcgta ccatccgtgc tgctattgat aatattgtcg gtcatggtcg tcctgcgcgt
    17941 gtgagtttag cagttctagt cgatcgtgga catagagaat tgccaatccg tccagattac
    18001 gttggaaaaa atatcccaac cagtcgttct gaagaaatca tcgtagagat gacagaactt
    18061 gatgaccaag acagagttct gattactgaa gaagcttaga aagttaaagg agtagccatg
    18121 tcagaaaatc aacaagcatt gaaccatgtg gtgtccatgg aagacctcac tgtcgatcaa
    18181 gtaatgaaat tgatcaagcg aggaattgag tttaaaaatg gagcccagct tccctatgaa
    18241 gaccatccga ttgtttccaa tctcttcttt gaggattcta cacggacaca taagtccttt
    18301 gaagtcgcag agattaaact tggattggaa cgacttgact ttgatgtgaa gactagttcg
    18361 gttaataagg gtgagacact ttatgacacc attttgactc tgtctgcttt aggagtggat
    18421 gtctgtgtga ttcgccatcc agaggtcgac tactatagag aattgattgc tagtccaacg
    18481 attacgactt ccatcatcaa tggtggagat ggttcgggcc aacaccctag ccagagcttg
    18541 cttgatttga tgaccattta tgaggaattt ggccactttg agggtcttaa agttgctatt
    18601 gcaggtgact tggatcactc acgcgttgcc aaatccaata tgcagatttt gaaacgcttg
    18661 ggagctgaac tctttttcgc tggacctgag gaatggagaa gtcaagagtt tgcagactat
    18721 ggacagtttg taaccattga tgaaatcatt gatcaggttg atgtcatgat gtttctccgt
    18781 gtgcaacacg aacgccatga tagtggagct gtattttcaa aagaagacta ccatgcccaa
    18841 catggcttga ctcaagaacg ttacgatcgt ttgaaagaaa cagcaatcct catgcaccca
    18901 gctccaatca atcgtgatgt agaaatagca gaccacttgg ttgaagcacc aaaatcacgg
    18961 attgtccaac aaatgaccaa tggtgtcttt gttcgaatgg caatcttaga atccgtacta
    19021 gcgagtagaa acgccaacta aaacacaaga cgttaaaaga cgccagtgag cgtccacgag
    19081 aggtgaaaat atgacaaaaa gaattctagt attagaagat ggcacagttt ttgaaggcaa
    19141 ggccttcgga gcagatattg atgtaacagg cgaaatcgtc tttaatacag ggatgaccgg
    19201 ctaccaagaa tccattacag accagtctta taatggacaa atcttgacct ttacttatcc
    19261 tttggtagga aattatggta ttaatcgtga tgattatgaa tccattattc caacttgtaa
    19321 gggagtcgtt gtttttgaag aagcgcgtag agctagcaac tggcgcaacc aaatgacctt
    19381 ggatgaattt ttgaaagcca aaaaaattcc agggatttca ggaattgata cgcgtgctct
    19441 taccaagatt atccgtaagc atggtactat gcgtgcaacc ttgacccatg ttggggacag
    19501 tatggaccat gtgacggacc agctccaagc aacagtttta ccgacagaca atatcaaaca
    19561 ggtttctact aaaacgtctt atccagctcc aggagttggt ttgagcgtgg tgctagtgga
    19621 ctttggtctc aagcactcaa tcctacgtga actttctaaa cgcaactgta acgtgacagt
    19681 tgttccttat tcgacaacgg ctgaagaaat tctccatctc aatcctgatg gggttatgtt
    19741 gtcaaatggt ccaggtaacc cagaagacgt tccacaagca ctcgacatga ttcgcggtgt
    19801 acaaggaaaa attccaatct ttggtatttg tatgggacac caactctttg caatggcaaa
    19861 cggggctaag acctataaga tgaagtttgg ccaccgtgga ttcaaccatg cggtacgtga
    19921 aatcgcaaca ggacgagtag acttcaccag ccagaaccat ggttatgcag tcagccgcga
    19981 ggatttgcca gagcacttga ttattaccca cgaagaaatc aatgacaagt cagtggaagg
    20041 tgtgcgccac agataccaac ctgctttctc tgttcaatac cacccagatg cagctcctgg
    20101 gccacacgac gctagctacc tatttgacga gtttatcgag atgatggaag tttttaaaca
    20161 atcaaactaa gaacgagtaa aagctcgtcg gagaatttat gtaactgaac acggacggaa
    20221 agctcagaat gtagagaaat caacttggat tgtcaatcct tccttgattt tctaaaattc
    20281 aatcgctttc tattcgtcct ttgtatctta tttaatgtcg ccctgagagg cgacgaatag
    20341 aaaggagaag ggtgctccgt atttgctgaa ctgaatacgg gctacggacg gtgctaaaaa
    20401 gatagttatt cctagaactg acagttcttc gtcataactc ctattttagc tttgtccgct
    20461 tgacgccctt aatatcttat atatgcctaa acgtactgat attcaaaaaa ttatggtgat
    20521 tggttctggt ccgattatta ttggccaggc tgctgagttt gactacgctg ggactcaggc
    20581 ttgcttgtcg ttgaaagagg aaggttatga ggttgttttg gttaactcaa atcctgcaac
    20641 catcatgacg gacaaggaaa ttgctgacaa ggtttacatt gaaccgatta cacttgagtt
    20701 tgtgacacgt attcttcgta aggaacgtcc agatgccttg ctaccaacac tcggtggtca
    20761 gacaggtctc aacatggcca tggaattatc taaaaatggt atcctagacg agcttggcgt
    20821 tgaacttctg ggtaccaaat tatctgccat tgaccaagcg gaggaccgtg acctctttaa
    20881 acaattgatg gaagagcttg aacaacccat tccagaatct gaaattgtta acacagtaga
    20941 agaagcagtt gcctttgcag cgacaattgg ctacccagtc atcgttcgtc cagcctttac
    21001 ccttggtggt actggtggtg gtatgtgtgc caacgagaaa gaattgcgtg aaatcactga
    21061 aaatggtttg aaattgtcac ctgttaccca atgtttgatt gagcgttcga ttgccggttt
    21121 caaggaaatt gaatacgaag tgatgcgtga ctcagctgac aatgccttgg ttgtttgtaa
    21181 catggaaaac tttgacccag ttgggattca cacaggggat tccattgtat ttgcccctgc
    21241 gcaaaccatg tcagactatg aaaaccaaat gcttcgtgat gcgagcttga gcattattcg
    21301 tgccctcaag attgaaggtg gatgtaatgt tcagctagct cttgatccta acagcttcaa
    21361 gtattatgtt atcgaagtaa accctcgtgt atcacgttcg tcagcccttg cttctaaagc
    21421 gacaggatat ccgattgcta agttggctgc caagattgca gtaggtttga ccttggatga
    21481 ggttataaac ccagttacag gttcaaccta tgccatgttt gaaccagccc ttgactacgt
    21541 agttgctaag attccacgtt tcccatttga caagtttgaa aagggtgaac gccgtctcgg
    21601 tacacaaatg aaggcgactg gagaagtcat ggcaatcggt cgtaacatcg aggaatctct
    21661 tctcaaggcc tgccgctccc ttgaaattgg ggtgcaccac aatgaaatac ctgaacttgc
    21721 agcagtttct gatgatgcct tgattgaaaa ggttgtcaaa gcccaagatg accgtctctt
    21781 ctacgtatca gaagcaattc gtcgtggcta cacacctgaa gaaattgcag agcttacaaa
    21841 aattgatatc ttctatcttg ataaactctt gcatatcttt gaaattgagc aagaattggg
    21901 tgctcatcca caagatctag aagttttgaa aacagccaaa cttaatggtt tttcagaccg
    21961 taagattgct gaactctggg gaacgactga tgataaagtt cgccaacttc gcttggaaaa
    22021 caagattgtt ccagtttata agatggtaga cacttgtgcg gcagagttcg actccgaaac
    22081 gccatatttc tattcaacct atggttggga aaatgaatct atcagatctg ataaagaatc
    22141 tgtacttgtc ctaggttcag gtccaatccg tatcggtcaa ggggttgagt ttgactacgc
    22201 aaccgttcac tctgttaagg ctatccaggc agctggttat gaagctatca tcatgaactc
    22261 aaacccagag accgtttcaa cagacttctc tgtatcagat aagctttact ttgagccatt
    22321 gacattcgaa gatgttatga acgtcattga cttggaacaa ccaaagggag ttatcgttca
    22381 gttcggtggt caaacagcca tcaaccttgc ggagccattg gcaaaagcag gtgtgaccat
    22441 ccttggtaca caggttgctg acctagaccg tgccgaagac cgtgacctct tcgagcaagc
    22501 tctcaaagaa ttggatattc cacagccacc aggacaaacg gctaccaatg aagaagaagc
    22561 agctcttgca gctcgtaaga ttggcttccc agttcttgtc cgcccatctt atgtacttgg
    22621 tggacgtgcc atggaaatcg ttgaaaacga agaagacctt cgttcttaca tgcgaactgc
    22681 tgttaaggct agtccagatc acccagttct tgtcgactct tatatcgttg ggcaagagtg
    22741 cgaagttgat gccatttcag atggtaaaga tgtactcatt cctggtatca tggagcatat
    22801 cgaacgtgct ggtgtccact caggtgactc aatggctgtt tacccaccac aaaccttgtc
    22861 gcaaaaggtt caggagacca tcgcagacta caccaaacgc ttagcaatcg gtcttcactg
    22921 ccttggaatg atgaacatcc agtttgttat caaggatgaa aaagtctacg ttattgaggt
    22981 caatccacgt gccagccgta ctgttccatt cctatctaag gtaaccaata ttcctatggc
    23041 tcaagtagcg accaagctca ttcttggtca aagtttatca gaacttggct accaaaatgg
    23101 actttaccct gaaagcaccc gtgttcatat caaggcacct gtcttctcct ttaccaaact
    23161 agctaaggta gacagcttgc tcggtcctga aatgaagtca acaggtgaag ttatgggttc
    23221 tgatgctact ttggaaaaag ctctctataa agcctttgaa gcttcttatc tacacttgcc
    23281 aacttttggt aatgtcgtct ttaccatcgc tgatgatgcc aaagaagaag ccttgaactt
    23341 ggctcgtcgt ttccaaaaca ttggttatgg aatccttgcg acagaaggga cagcagcctt
    23401 ctttgctagc catggcttgc aagcccaacc tgttggtaag attggtgatg acgataagga
    23461 tatcccaagt tttgtacgca aaggaagaat tcaagctatc attaacacag taggaacaaa
    23521 acgaactgct gacgaagatg gtgagcaaat tcgtcgttca gccattgaac acggggtgcc
    23581 cctcttcaca gcgctagata cagctaatgc catgcttaag gtacttgaaa gtcgtagctt
    23641 tgttacagaa gcgatttaaa tagaaaaata agatatagca gactgaattt agaacagtac
    23701 acagggatac taaaatattt ctagaaatta atttgaattt tctaattgat tcgttcgcat
    23761 cttatttcaa tctactatag aaaaaagtct ttaaaattat aaaacgcatc atatcaaggt
    23821 ttttcaaaaa ccttgatatg atgcgtttta ttgtgggaat atgtatttca ttttctacta
    23881 aaattatgtt tttgaataac ctctatctta gtagtttgta taatacccct caatcagttt
    23941 ttgcgataag ctttaatgct atgactatac cactcttgca tttcttttga tggtggtgtc
    24001 atataatcgc catacatctg ggttaaaaat tggtcatatt ttttgggaac aggcaacata
    24061 cggccctcaa actcagttaa aatcagttct ttaaaggtat caactgggaa gatttctttc
    24121 atcccttcct taccgatccc aactcctcct tcatattgag gagtgttggt tacagcattt
    24181 ttgactagtt gatcaatttt cttgtaaaag tagcgaggat tgacaaatcg gagagcgtac
    24241 cagctacata atctaagaaa atcttttagt ttgctatcac cgtgaactgc tcgtgatttt
    24301 ttgatataag ctagttgacg aagagccaca tacttatagc tcttgtcgac aatgctcaag
    24361 tctgtaaatc gatcaattgg gaagacatcg atgaaaaggc tggtatcatg acgcttgtac
    24421 ttaacatggt cttctataac agtagaagtg tccaaaatcg atgcgaaatt atggaagtac
    24481 caagaagatg tatcgtagga aagaaccttg tagcgagggt gattttcttc ttcaataatc
    24541 ttcagtaaac gctcataatc ctcacgataa agggaaatat caatatcatc atcccaagga
    24601 atcatacctt tgtggcggat ggctccaagc atggttccat aactgagaaa ataaggaata
    24661 tcatgtttct tacaagtctc atcaatatag tccagcaggg ctagttgaat ttctttaatt
    24721 tctttttttt ctaaatattg catcctaatc ctccaattta taagcgtgaa attcatgact
    24781 gtagaagcgt ttttcttctg gtggtagggt catataatct ccataaaatt gtgtcaaaat
    24841 agtatcaaat ttttcaggtg caggaaggct taaattctca aagggtaaat cgattgtttt
    24901 atcaaaggta ccacttggga agacttcctt ttccttaaat tttgaaggaa taaaagccat
    24961 atactgccca ttttcacgac tatatttttg aatttctttc tcgattttat ttgcaaaata
    25021 acgaggagaa accggtcgaa ggagcaacca aaaggctgtt cgtatccaat cttttaaaag
    25081 gctatcctta tagacaatat ttttatgttt actgaaagac agcagtttga agctttccag
    25141 tttataacaa gtatcaatga ccttaggatc atcaaagcga tctataggga aaatatcgat
    25201 aaagatacca gactcatagg tttttgtatt tcgagtatca ataattttag ttgtactgtc
    25261 ggttatcttg ataaagttgt taaagtagtt cttatcagtt tctaaggata ggagcttata
    25321 cttgcttttt tccttttgaa aaatgttaat aaatcgttgg tagtcttctc taggcatgga
    25381 taaatcaata tcgtcgtccc aagggataaa gccctcatgt cgaaccgccc caatcagagt
    25441 accgtagtta ataatatagt tgatattgtg ctttttacag agagtatcaa tataattcaa
    25501 aatttctaat tcaatttgtt tggcatcttc aacggttagt tgtttcattt taaactccta
    25561 agatttttta aatttatttt ttaaggctag gacatggttt aaaaattcat agaaaatgct
    25621 atcttttgtg aagacaagta gactaatata agagatagct gatagcaaga caatcaaacc
    25681 agtattaatc aaaaatggca aattaatgac catatccaca ggatacatga aattaatcag
    25741 gaaataaatt gctacaaagg aaagtgaaaa gagagagtat cgaacagtat agctaaagat
    25801 atgtcccaag tggatgagtt gttttctatg gatgaaaatg atatagaaaa caagtagaga
    25861 agtctctgat aacatagttg tcagtaagta gtattcagga gccacgatat ggttgaaaaa
    25921 gaggagacta ttcaagccca aattgagtag cccagcaaag actgtataga ctgtgatacg
    25981 tttttcatag ccattggtaa agagaatttg ggaaccaaga atggtatcta aggccaggat
    26041 aatcgtacga aaagcgaaga gagaggtcaa gatgccgcct ccgatatatt tttcactacc
    26101 gtaaagtagg atggcatttg gtcctaaaac catgagtcca aaactcagtg gaatgataaa
    26161 gaagttaaag attcgactac ctctattaac cagagaaaca taggcttctt tgtctccttt
    26221 ccccagatag taactgagac gaggcacact cactccaatt gcacctgtta caaccccagc
    26281 tataacggtc acaattcgct gagctatggt atagtaacta acgttgacat caatccctgt
    26341 tttaacgagg aagaggcgat ctaaaaaagt gaagagcata ttggcattgg caaagactaa
    26401 catggctgtc agagggagaa agagtggttt aaaatcactt aggtgaattt taacaagttt
    26461 gatgtctctt ttaatccaaa aataactaat caggtagtta atcagcgtcg ataaactcat
    26521 cacaagtgta tagacaacaa tatcgtgttc atttttaaca aataagaaaa tagagaccag
    26581 catcaggata cggatgaagg cagttttgta aaagagaaaa ctgtaatttt ccagagcttc
    26641 attgacccat tcgattgaaa aaatctgggc aatgagttga atccccataa caaggtagac
    26701 ctttttgacg attggattat cagtaaagaa gagaggatag gctaggatat agacagcagt
    26761 ggtcaaaatc gtacaagcga tgcacaaata aaaaagacta gaaaaggttc tgttaagatc
    26821 ttttttgtta tccttgacat tactgatagc ccttaaaccg tagttataga caccataagt
    26881 tgcaaagggc aagaaaaatg acaaaatagt gtcgactgag ttgaagtaac catagtcagt
    26941 tcggtccaag acacgcgcga cataggttcc agttaggatg ggaaaaataa tattcaagac
    27001 acgaattccc atgtaagata gagcatttaa ttttatactt ttcattcaat ttacctcgtt
    27061 tttcattata tcataaagtt agctaataag aaatgaaggg cagtaagtca agtaatcact
    27121 ttgaagtttc aaatcttaaa ttttaagttt tctttaagga aagtatatta ttctgaagga
    27181 ctctaaaatt tcgcagccat ttattagtaa ttgctacaga attcctagtc attactagaa
    27241 atgaactagt ttctttgaat aatagaactg cataattctc ctattctaga aggggaggac
    27301 cagtatttct tttatgatag gactagattg tggtataata gagagaataa gtttttttag
    27361 taagacaaag gagaaaatag atgatttatg caggaattct tgccggtgga actggcacac
    27421 gcatgggaat cagtaacttg ccaaaacaat ttttagagct aggtgatcga cctattttga
    27481 ttcatacaat tgaaaaattt gtcttggagc caagtattga aaaaattgta gttggggttc
    27541 atggagactg ggtttctcat gcagaagatc ttgtagataa atatcttcct cttcacaagg
    27601 aacgtatcat cattacaaag ggtggtgctg accgcaatac aagtattgag aaaatcattg
    27661 aagccattga tgcttatcgt ccgcttactt cagaggatat cgttgttacc cacgattctg
    27721 ttcgtccatt tattacactt cgcatgattc aggacaatat ccaacttgcc caaaatcatg
    27781 acgcagtgga cacagtggta gaagcggttg atactatcgt tgaaagtacc aatggtcaat
    27841 ttattacaga tattccaaat cgtgctcacc tttatcaagg acaaacacct caaacattcc
    27901 gttgcaagga cttcatggac ctttatggat ctctttctga tgaagagaag gaaatcttga
    27961 cagatgcatg taaaatcttt gtgatcaaag gaaaagatgt ggccttggcc aaaggtgaat
    28021 actcaaatct gaagattaca accgtaacag atttgaagat tgcaaaaagt atgattgaga
    28081 aagactagta aaatgattaa tcaaatttat caactaacta agcctaagtt tatcaatgtc
    28141 aaatatcagg aagaggttat tgaccaagag aatcatatcc ttatccgtcc caactacatg
    28201 gctgtctgtc atgcggatca gcgttactat cagggaaaac gtgatcccaa gattttgaat
    28261 aaaaagcttc caatggcaat gattcacgag tcatgtggaa ccgtcatttc tgacccgacc
    28321 ggaacctacg aggttggtca aaaagttgtc atgattccca atcagtctcc tatgcagagt
    28381 gatgaagaat tctatgaaaa ctacatgaca gggacccatt tcttgtctag tggatttgat
    28441 ggctttatga gagagtttgt ttctctccct aaagatcgtg tggtggctta tgatgctatt
    28501 gaagatacgg ttgcagccat tacagagttt gtcagtgtgg gcatgcacgc tatgaatcgt
    28561 ctattgactc ttgctcatag caagcgggag cggatcgccg ttattggaga tggaagttta
    28621 gcttttgtgg ttgccaatat tatcaactat actttgccag aagcagagat tgtggttatt
    28681 ggtcgtcatt gggaaaagtt ggaactcttc tcatttgcca aagaatgcta tattacggat
    28741 aatattcctg aagatttggc ctttgaccat gcttttgaat gttgtggtgg tgatggtact
    28801 ggaccagcta ttaatgactt gattcgctac attcgtcctc agggaacgat tctcatgatg
    28861 ggagttagcg aatataaagt caatctcaat actcgcgatg ccttagaaaa gggcttgatt
    28921 ttggttgggt catctcgttc tggtcgcatt gattttgaaa atgctatcca aatgatggaa
    28981 gtcaagaaat ttgccaatcg tcttaaaaat atcctttatc tagaagaacc tgtaagagaa
    29041 attaaagata ttcatcgtgt ctttgcaacc gatttaaaca cagcctttaa aacagtgttt
    29101 aagtgggaag tataagtact ggaggttaat tgtggagaaa atcattaaag aaaaaatttc
    29161 ttccttactt agtcaagaag aggaagtcct cagtgttgaa caactggggg gaatgaccaa
    29221 tcaaaactat ttggccaaaa caacaaataa gcaatacatt gttaaattct ttggtaaagg
    29281 gacagaaaag cttatcaatc gacaagatga aaagtacaat cttgaactac taaaggattt
    29341 aggcttagat gtaaaaaatt atctttttga tattgaagct ggtatcaaag taaatgagta
    29401 tatcgaattt gcgattacgc ttgattcaac gtcaatcaag accaagttcg acaaaattgc
    29461 tccaatatta caaactattc atacgtctgc taaggaatta agaggagaat ttgctccttt
    29521 tgaagaaatc aaaaaatacg aatccttgat tgaagaacaa attccttatg ccaactatga
    29581 atctgttaga aatgcagtct tctccttaga gaaaagactg gctgacttag gtgttgacag
    29641 aaaatcttgt catatcgatt tggtgcctga aaactttatc gaatcacctc aaggacgact
    29701 ttatttgatt gactgggaat attcatcaat gaatgatcca atgtgggatt tggctgccct
    29761 ctttttagag tctgaattca cttcccaaga ggaagaaact ttcttatctc actatgagag
    29821 tgaccaaaca ccggtttctc atgaaaagat tgctatttat aaaattttac aagatactat
    29881 ttggagtcta tggactgtct ataaggaaga gcaaggtgaa gattttggtg actatggtgt
    29941 gaatcgttac caaagagctg ttaaaggttt ggcttcttat ggaggttcag atgaaaagta
    30001 aaaacggagt tccttttggc cttctctcag gtattttctg gggcttgggt ctaacggtta
    30061 gtgcttatat cttttcgatt tttacagatt tgtcaccctt tgtggtggct gcagctcatg
    30121 attttttgag catctttatc ttactagctt ttctcttggt aaaagaaggg aaagttcgcc
    30181 tctcaatttt cttaaatatt cgcaatgtca gtgttatcat cggagccttg ctagcaggcc
    30241 ctatcggtat gcaggccaat ctttatgcag ttaagtatat cggaagttct ttagcttcat
    30301 ctgtatcggc tatttaccct gcgatttcag ttctattggc tttcttcttt ttgaagcaca
    30361 agatttcgaa aaatactgta tttgggattg tcttgattat tggagggatt attgctcaga
    30421 cctataaggt tgaacaggtt aattctttct acattgggat tctttgtgct ttggtttgtg
    30481 ctattgcatg gggaagtgag agtgttctta gctcttttgc catggaaagt gaattgagtg
    30541 aaatcgaagc cctcttaatc cgtcaagtaa cttcgttctt gtcctatctt gtgattgtgc
    30601 tcttctctca tcagtcattt actgcagtag ccaatggaca attgctaggt ctcatgattg
    30661 tttttgcagc ctttgatatg atttcctact tggcttatta tatcgctatc aatcgcttgc
    30721 aaccagccaa ggctacaggc ttgaacgtga gctatgtagt atggacggtc ttgtttgcag
    30781 ttgttttctt gggtgcaccg ctagatatgc tgaccattat gacgtcactt gtcgtcattg
    30841 ctggagttta tattattatt aaagaataaa ggagattcgt gtgaaagcca ttatcttagc
    30901 agcgggattg ggaactcgct tgcgtcctat gactgaaaat acccctaaag ccttggttca
    30961 ggttaatcaa aaacccttaa ttgagtacca aattgagttt ctcaaagaaa aaggaatcaa
    31021 tgacatcatc atcattgttg gttatcttaa agaacaattc gattacttaa aagaaaaata
    31081 cggtgttcgc ctcgttttca atgataaata cgctgactac aataactttt actctctcta
    31141 tcttgtaaaa gaagaattgg ccaacagcta tgttattgat gctgacaatt atctctttaa
    31201 aaatatgttc cgcaatgatt tgactcgttc gacttatttt agtgtttatc gtgaagattg
    31261 taccaacgaa tggttcttgg tctatggaga tgactacaag gttcaagaca ttattgttga
    31321 tagcaaggca ggtcgcatcc ttagtggtgt atccttctgg gatgctccaa ctgcagaaaa
    31381 gattgtcagc tttatcgata aggcttatgc aagtggcgaa tttgttgatc tctattggga
    31441 caatatggtt aaggataata tcaaagagct agatgtctat gttgaagaat tagaaggcaa
    31501 tagcatttat gagatcgata gtgtccaaga ctatcgtaaa ttagaagaaa tttttaaaaa
    31561 cgaaaattaa agattccaac atctgacaaa atagtcggat gttttttgat tttttacgaa
    31621 cttttacgaa tagatagatg agtagaaaaa gaaatggagt tatttatgaa aatcacaaac
    31681 tatgaaatct ataagttaaa aaaatcaagt ttgaccaatc aacagatttt gaaagttcta
    31741 gaatacggtg aaaatgttga tcaggagctt ttgttgggtg atattgcaga tatatcaggt
    31801 tgccgtaatc cagccgtttt tatggaacgt tattttcaga tagacgatgc gcatttgtcg
    31861 aaagagtttc aaaaatttcc atctttctct attttagatg actgttatcc ttgggatttg
    31921 agtgaaatat atgatgcgcc tgtactttta ttttacaagg gaaatcttga cctcctgaaa
    31981 ttcccgaagg tagcggtcgt gggcagtcgt gcttgtagca aacagggagc taagtcagtt
    32041 gaaaaagtca ttcaaggctt ggaaaatgaa ctggttattg tcagtggtct ggccaagggc
    32101 attgacacag cagctcatat ggcagctctt cagaatggcg gaaaaaccat tgcagtgatt
    32161 ggaacaggac tggatgtgtt ttatcctaaa gccaataaac gcttgcaaga ctacatcggc
    32221 aatgaccatc tggttctaag tgaatatgga cctggcgaac aacctctgaa atttcatttt
    32281 cctgcccgta atcgcatcat tgctggactt tgtcgtggtg tgattgtagc agaggctaag
    32341 atgcgttcag gtagtctcat tacgtgtgag cgagcaatgg aagaaggacg cgatgtcttt
    32401 gctattcctg atagcatttt agatggacta tcagacggtt gccatcattt gattcaagaa
    32461 ggagcaaaat tggtcaccag tgggcaagat gttcttgcgg aatttgaatt ttaaaaatga
    32521 cctaagctag aattctaaga aaaaatcaat tttaagagaa aatgaaccca acatttccat
    32581 aataaaacgc atattagcaa gtttttaaca cttgataata tgcgtttttt ctaagtggat
    32641 tagtagagta gaggattttt ctcatataat actcttcgaa aatctcttca aactacgtca
    32701 gcttccatct gcaacctcaa aacagtattt tgagctgact tcgtcagtct tatctacaac
    32761 ctcaaagcag tgctttgagc aacctgtggc tagcttccta gtttgcgctt tgattttcat
    32821 tgagtataag ggaaagtata gtgaattgaa ataagatgtg aacaactcta tcaggaaagt
    32881 caaattaatt tatagaaata ttttagcagc caaggtgcac tgttatagat tcaatacact
    32941 ataatttagt gtaattgaga aaggagaaat gattgtgatt gatgttggct aggttatgtt
    33001 caatgattcc taccgtctca aatcttgtca gtaaggaaaa ataaattctt caaaagtaga
    33061 gattacaagg cttgtttaag aaagaattca aagaccttga caaataaaaa taaaatggtt
    33121 attataagaa atggtctaaa atagatgatg atacttttcg aaaatctttt tacgtcagct
    33181 cagctttgcc ttgctgtgtt ttgagcaagc tacggttagc ttccgagttt gattttcatt
    33241 tactagaaat gaaactgatg agagatatca gtagacattt gagtcaggat attatggaaa
    33301 atgataaaaa gagctcgtga gattggcata tcagactact aaagtattga gtttgttagg
    33361 attttagcga ctagttagct gggaaaggaa gatatttgtg acaaataata aactgtattc
    33421 gttgatagaa tttagaaata aaatatatga agaattagaa ctttccagaa gtgatttagc
    33481 gattttacta tgtgccatgc ttatcgcctc tatcggatta aatatggatt cgactcccgt
    33541 gattattgga gccatgttaa tctctccttt gatgacacct attctgggag tggggctctc
    33601 tctagctata tttgatttta aattgttaag aaaatctttt aaaatattag ctattcaaat
    33661 tcttgccagt ctaatagctt caacacttta tttttatctt tctcccattt cgtatgctag
    33721 ttcggagatt gttgctagaa cctctccgac tatttgggat gttctcattg cttttgtagg
    33781 agggatagca ggtattattg gtgctaggaa aaaagagacc aataatattg ttcctggtgt
    33841 tgctattgca accgccttga tgcctcctct ttgtacagta ggttatgcta ttgcttctgc
    33901 taatctaaaa tttatcatag gctcctctta cctattcctc atcaattgta gctttattgt
    33961 cattgcgact tatataggtg ttaggttgat gatggttaag aaacattatt ttaaagataa
    34021 cgaagaagac tctaaaatgc gtaggatttt gcttctagtt gctgttttgc tgatgattcc
    34081 gagtttcatc tctgcaacga ctttagtgag agaaacgttg aaaaaagagt cccttaagaa
    34141 atttatatca gagcagtttc aggggtataa tattttgaaa aaaacctatt ctaaaaagac
    34201 tcatacccta aagctaacca tttcaggaaa ttatttgaca gaagaagaac tcgatatgat
    34261 ttcaagtaag agaggtgact atggtttaag tgatgtttct gttcaagttt cacaattgtc
    34321 tgattcagaa caacttagta aggaagagct ggtggagtat ttcttccagt atatcaagga
    34381 taaggaagca aaagaaaagg agaaagccaa taaatttgat acagagtctg aggagcaata
    34441 atttcttgag aatagctggt ttctctcgtg agtcttctat gtatatcaaa ggaagactga
    34501 ggttttaagt ataaaacttt tcttctatta tagtagctaa gtcttgacag ggttcaaaaa
    34561 atggtttaca ctttataaag tttattactt tgaaaaggtg tgatactgtg gctacggcaa
    34621 caaaaaagaa aaaatcaaca gttaaaaaaa atctagtcat cgtggagtcg cctgctaagg
    34681 ccaagacgat tgaaaaatat ctaggcagaa actacaaggt tttagccagt gtcgggcata
    34741 tccgtgattt gaagaaatcc agtatgtccg tcgatattga aaataattat gaaccgcaat
    34801 atatcaatat ccgaggaaaa ggccctctta tcaatgactt gaaaaaagaa gctaaaaaag
    34861 ctaataaagt ttttctcgcg agtgacccgg accgtgaagg agaagcgatt tcttggcatt
    34921 tggcccatat tctcaacttg gatgaaaatg atgccaaccg tgtggtcttc aatgaaatca
    34981 ccaaggatgc agtcaaaaat gcttttaaag aacctcgtaa gatcgatatg gacttggtcg
    35041 atgcccaaca agctcgtcgg atcttggatc gcttggtagg gtattcgatt tcgcctattt
    35101 tgtggaagaa ggtcaagaag ggcttgtcag caggtcgcgt tcagtccatt gcccttaaac
    35161 tcatcattga ccgtgaaaat gaaatcaatg ccttccagcc agaagaatac tggacagttg
    35221 atgctgtctt taaaaaggga accaaacaat ttcatgcttc cttctatgga gtagatggta
    35281 aaaagatgaa actgaccagc aataacgaag tcaaggaagt cttgtctcgt ctgacgagta
    35341 aagacttttc agtagatcag gtggataaga aagagcgtaa gcgcaatgct cctttaccct
    35401 ataccacttc atctatgcag atggatgctg ccaataaaat caatttccgt actcgaaaaa
    35461 ccatgatggt tgcccaacag ctctatgaag gaattaatat cggttctggt gttcaaggtt
    35521 tgattaccta tatgcgtacc gattcgactc gtatcagtcc tgtagcgcaa aatgaggcgg
    35581 caagcttcat tacggatcgt tttggtagca agtattctaa gcacggtagc aaggtcaaaa
    35641 acgcatcagg tgctcaggat gcccatgagg ctattcgtcc gtcgagtgtc tttaatacac
    35701 cagaaagcat cgctaggtat ctggacaagg atcagctcaa gctatatacc cttatctgga
    35761 atcgttttgt ggctagccag atgacagcgg ccgtttttga taccatggct gttaaattgt
    35821 ctcaaaatgg agttcaattt gctgccaatg gtagtcaggt taagtttgat ggttatcttg
    35881 ccatttataa tgattctgac aagaataaaa tgctaccaga tatggctgtt ggagatgtgg
    35941 tcaaacaggt taatagcaaa ccagagcaac atttcaccca accgcctgcc cgttattctg
    36001 aagcaacact gattaaaacc ttagaggaaa atggggttgg acgtccatca acctatgcgc
    36061 caaccattga aaccattcag aaacgttatt atgttcgcct ggcagccaaa cgttttgaac
    36121 cgacagagtt gggagaaatt gtcaataagc tcatcgttga atatttccca gatatcgtaa
    36181 acgtgacctt cacagctgaa atggaaggta aactggatga tgtcgaagtt ggaaaagagc
    36241 agtggcgacg ggtcattgat gccttttaca aaccattctc taaagaagtt gccaaggctg
    36301 aagaagaaat ggaaaaaatc cagattaagg atgaaccagc tggatttgac tgtgaagtgt
    36361 gtggcagtcc aatggtcatt aaacttggtc gttttggtaa attctacgct tgtagcaatt
    36421 tcccagattg ccgtcatacc caagcaatcg tgaaagagat tggtgttgag tgtccaagct
    36481 gtcatcaggg acaaattatt gagcgaaaaa ccaagcgtaa tcgccttttc tatggttgca
    36541 atcgctatcc agaatgtgaa tttacctctt gggacaagcc tgttggtcgt gactgtccaa
    36601 aatgtggcaa cttcctcatg gagaaaaaag tccgtggtgg tggcaagcag gttgtttgta
    36661 gcaaaggcga ctacgaggaa gaaaagatta aataagagga ggggcccgaa agtaaatttc
    36721 aggctccttt tggttagaac ttgacaaaat acatcatttt atgcgaaact agaagaagat
    36781 tattttaact aggagaagtt atgcgtctta tctatctgat aattggtttt ttatcactgg
    36841 ccttggctat tgttggggtt gttttaccct tgttgccgac aacgcctttc cttttgttgt
    36901 ctattgcttg tttctccaga agttccaagc gtttcgaaga ctggctttat cataccaagc
    36961 tctatcaaac atatgtagct gattttcgcg agactaagtc tattacgcgt gaacgaaaga
    37021 aaaaaatcat cgtctctatc tacgtcttga tgggaatttc tatttatttt gcacctcttt
    37081 taccagtcaa aatcggtctg ggtgctttga ccatctttat cacttattat cttttcaagg
    37141 tcattccaga caaagaatag ttaaaacagt agttatttgc cttgataaaa ttgaaagcat
    37201 attcataata atatgatata ataaatttga agtaatattc aaggagaatc aaatgattta
    37261 cgaattttgt gctgaaaatg tgactttact tgaaaaagcg atgcaggctg gagctcgtcg
    37321 gattgaactc tgtgataatc tagcagttgg tgggacaaca cccagctatg gagtgactaa
    37381 ggcagcggtt gaactggcag ctaactacga tacaaccatc atgaccatga ttcggccacg
    37441 tggtggtgac tttgtctata atgacctaga aattgctatc atgctagaag acattcgttt
    37501 gactgctcag gctggaagtc aaggggttgt atttggaact ttaactgctg ataaaaagtt
    37561 ggataagcct aatctggaaa agttaattgc tgcatcaaaa ggaatggaaa ttgtctttca
    37621 catggccttt gatgaactaa gtgatgaaga tcaaccggaa gctattgact ggctcagtca
    37681 agccggtgtc actcgtatcc taactcgtgc tggtgtgtct ggcgactcct tagaaaaacg
    37741 ttttgttcac tatcacagaa ttttggagta cgctaaaggt aaaattgaaa ttctaccagg
    37801 tggggggatt gaccttgaaa accgtcaaac ctttatcgac caggtggggg taacacaatt
    37861 gcatggtact aaggttgttt tttaaaaaat agaaaggaac tgctagcttt gggtagcagt
    37921 tttcacttat gtttgaaatt tttaaatcct atcaatttaa tcaagaaaag gctcatgatt
    37981 atggttttat agaaaatagc gaagtctgga catatagttg ccagattttg caaggtgact
    38041 ttgtcatgac tgtgtccatc actgctgata atgtgaactt tcaagtcttt gaccaagaga
    38101 ctggtgacct ctatcctcac gttcatatgg aaagcatgag gggaagtttt gtcggaaatg
    38161 tccgtgaggc ttgtctggag attctttacc agattcggaa ggcttgtttt gatgtgcaag
    38221 attttatctg tcatcagact aagcgtatca tgactcaagt tcaggaaaag tatggaaacc
    38281 agttggagta tctgtgggaa aaatcgcctg atacagctgt attgcgccat gaaggcaatc
    38341 aaaagtggta tgccgtcttg atgaaaatct cttggaataa gctggaaaag ggcagagaag
    38401 gacaagtgga agcagtcaac ctcaagcatg accaagtagc taatttgctt tcacaaaagg
    38461 ggatttatcc agccttccat atgagcaagc gctactggat tagtgtgtcc cttgatgata
    38521 ctttatcaga tgaagaagta ctggaattga tagaaaaaag ttggaactta acctctaaaa
    38581 aatgaaatat tttaataatt ttcatgaact ttcaattagc taaatattct ttactgaaga
    38641 aattttcaga aaatatagga tttaccacac cagaggaata tggtgccatc ttcaaatacc
    38701 tgattgagaa tgtcaagacg gatcgtcaga tcatctattc gcctcactgt catgatgacc
    38761 tcggaatagc agtggcaaat agccttgctg ctgtcaagaa tggtgcagga cgtgttgaag
    38821 agactatcaa tggtattagg gagcgagctg gaaatgctgc tttggaagaa attgcagtgg
    38881 ctctcaatat tcgccaagat tactaccaag tagaaaccag tattgtccta actgagacca
    38941 tcaatacgtc agaaatggtt tctcgcttct ctggtattcc agttcctaaa aacaaagccg
    39001 tcgttggtgg caataccttc tcccacgaat ctggtattca ccaagatgga gtccttaaaa
    39061 atcctctcac ttatgagatc atcacacctg aattggttgg tgttaagatt ccgcttggaa
    39121 aattatctgg tcgccatgct tttgttgaga aactgagaga attggcccta gattttacag
    39181 aagaggatat caaaccactc tttgctaagt tcaaggcact ggtcgataag aagcaagaaa
    39241 tcacagatgc agatattcga gctttggtag ctggaaccat ggttgaaaat ccagaaggct
    39301 tccactttga tgatttacaa cttcaaactc atgcagataa tgacattgaa gcgctcgtta
    39361 gcctagccaa tatggatggt gagaaagtcg aatttaatgc gacagggcaa ggttccgttg
    39421 aagcaatctt taatgctatc gataagttct ttaaccaatc tgttcgtttg gtgtcctaca
    39481 ctatcgatgc ggtaacagat ggaatcgata cccaggaacg ggttttggtc actgttgaaa
    39541 acagagatac agaaaccatc ttgaatgcag cagggcttga ttttgatgtg ttgaaggctt
    39601 ctgctattgc ctatataaac gctaatacct ttgttcaaaa agagaatgca ggtgagatgg
    39661 gacgcagtgt ttcttaccac gatatgccta gtgtgtaaag gagaaggcta tggcaaagaa
    39721 aatagtagct ctagcaggag acggaattgg cccagaaatc atggaggctg gtttagaagt
    39781 tctggaggct ctagctgaaa aaacaggttt tgactatgag atcgttcgga ggtgcagata
    39841 ttgatgcagc aggatctccc ttacctgatg aaacccttaa ggcaagtagg gaagcagatg
    39901 ctatcctact agtagctatc ggtagtcctc agtatgatgg agtagcggtt cgccctgaac
    39961 aaggcctgat ggctctccgt aaggaactca atctttacgc taatattcgt cctgtaaaaa
    40021 tctttgacag tctcaagtat ttgtcaccac tcaaaccgga acgaatttct ggtgtagact
    40081 ttgtcgtggt gcgtgaattg acaggcgaga tttactttgg agatcatatt cttgaagagc
    40141 gcaaagcgcg tgatatcaac gactatagct atgaggaagt ggagcggatt attcgcaaag
    40201 cctttgaaat tgcaagaaat cgcagaaaaa tcgttactag tatcgataag caaaatgttc
    40261 tagcgacctc aaaactctgg cggaaagtag ctgaggaagt cgcacaggat ttcccagatg
    40321 taaccttgga acaccagctg gtagactcag ctgctatgct tatgattacc aatcctgcta
    40381 agtttgatgt tattgtaacg gagaatcttt ttggagatat tttatctgat gaatcaagcg
    40441 tcttatctgg tacacttgag gttatgccat cagccagtca ttctgaaaat ggaccaagtc
    40501 tctatgaacc tattcacggt tcagcacctg atattgcagg tcaaggaatt gccaatccta
    40561 tttccatgat tttattagtt gtcatgatgt tgagagatag tttcggacgt tatgaggata
    40621 cagagcgtat caaacgtgct gttgagacaa gtctggcggc aggaatttta acgagagata
    40681 taggaggtca ggcttcaaca aaggaaatga tggaagctat tattgcaagg ttatgaagtt
    40741 agacgaaaaa attactctag tccttttgat ttggaatgtc atcattttct tgatttatgg
    40801 cattgacaaa ttcaaggcaa gaagaagagc ttggcgcatc ccagagaaaa tcttactcat
    40861 tttagccctt acttgtggtg gttttggggc ctggttagct ggaatcactt ttcaccacaa
    40921 gactcgaaaa tggtacttta aaacagtttg gtttcttggg atggtgacca cactagtagc
    40981 cttatatttt atttggaggt aatggatggt agggtcttcg agggaacacg ctgcttgggc
    41041 tctagcggac tatggtttta aggtcgtgat tgcaggatct ttcggtgaca ttcattacaa
    41101 taatgaactc aataatggca tgttgccaat cgttcagcct agagaggtta gagagaaact
    41161 agcccagcta aaaccaaccg accaggtaac tgtggacttg gaacaacaaa aaatcatctc
    41221 accagttgaa gaattcacct tcgagataga tagcaagtgg aaacataaac tcctaaatag
    41281 tttggatgat atcggtatta ccttgcagta tgaagagttg attgctgctt atgaaaaaca
    41341 acgaccagcc tactggcagg attagaaaaa atagaaaagg aaatatagta aactgaaata
    41401 agatgtaaac aaatgaattg gagcttaaca tccatttcca gcaatttttt agaaactaca
    41461 gtggactatt ctggattcaa cacattataa aattatgaca aaacacattc acaagaaggc
    41521 tacgacattt taaaaggtga gggcggatgt atcgtttgcc ctactaaagt tggttacatt
    41581 atcatgacca gcaacaaggc aggacttgag cgtaagttcg cagccaaaga acgtaagcgt
    41641 aacaaaccag gtgttgttct ctgcggtagc atggatgaac ttcgcgcttt agcgcaactc
    41701 aacccagaaa ttgaagcatt ctactaaaaa cattggatga agatattctt cttggttgta
    41761 tccttccttg gaaaccagaa gcctttgaaa aactcaaagc atacggggat ggccgtgaag
    41821 aacttatgac tgatgtacgt ggtactagct gttttgttat caagtttgga aaagcaggtg
    41881 aacaattggc tgccaagctt tgggaagaag gtaaaatggt ctacgcctca tatgcttcaa
    41941 tgacaaaacg attgaaactc gctatgagag caaggtgtaa tggtgtctat ggtcgataag
    42001 gacggcaaac tcatcccaga acaaggagga gcacgttcaa cttcaccagc accagttgtg
    42061 atccgtaaag ggcttgacat tgataaaatc atgatgcacc tgtcagatac ttttaactca
    42121 tgggactact gtcaggttga gtattattaa gataaaaaaa gaagtctagt gttatgagat
    42181 attaaagctc ctaacactgg actttttgtt tagaatttct tttctttttc tataggatat
    42241 ggtattctat gtagaaaata tatgttaata agtaatgcca atatttaaac atcattagta
    42301 aaaggagtta gattgatgaa taaaagaaaa gttagtttag aagattttta taaatggtat
    42361 agtctaaata aagaagagtt attaaataag gcaactgttg gtgaaaagtt taatgataaa
    42421 ttaaaagaag agtttctcca ggaatggcct ttggatagga ttttaacaat gtcaatcgat
    42481 gaatatgtaa taggaaaggg acagcaaaat aagtctttat gctacgctct tgagaaggga
    42541 aaatacaaaa atctatttct tggaatttct ggtggctcag cttcaaaatt tggtatttat
    42601 tggaataaaa aaacaaacaa atataaagat caagctaata atgagatttc agagttggat
    42661 cagcgatttt caaaattaaa atcagatttg tatgaaatta tcaaagaagg tattcgtttt
    42721 aactttgaaa atcctatttt tgatatgaaa agatcaacaa atgaatttat tggtcgttct
    42781 gctatggtga caaaattact ttgtatctat actgagggag atcctttctt tggtgtaaat
    42841 attaatagtc agaaagaatt ttggaaccac tttgtttctc agacaaatca aggtggacct
    42901 tatctgcaaa atcataaaat aattgaactg gtgtccaaaa cttatcctga gttggagcca
    42961 tcgaaattag gaactatgct ttttgagtat tctaagcttt ttatggaaaa taaggaagac
    43021 aatagtacaa tggattcatc aaacaatttt agtcatcaat taactcaatc tctattaaag
    43081 tctccaaacc ttatccttcg tggtgctcct ggcacaggaa agacttatct tgctaaagaa
    43141 attgccaaag aattaacgga tggcaacgaa gaccaaatcg gatttgtaca atttcaccca
    43201 tcctatgatt atacggattt tgtagaaggt ttaagaccag tatcaaatgg ggatggagct
    43261 attgagttta ggctacagga cggtattttt aaagattttt gtcagaaagc aaaagaaacc
    43321 caattgattg gaggacaaga taattttgat gaggcttggg attcttactt agaatatata
    43381 aatgttgctg aagaaaaaga atatataaca aaaacatctt acttatctgt taatagtaga
    43441 caaaatttgt cagtaaatta tgatagtggt gttccaggat ggtcactacc tagcaaatat
    43501 gtttacgagt tgtataaaga taaaaattat aataagcaag aatactacaa aagtggtgga
    43561 aaaactgtcc tagaaacatt gagaaagaga tttggtttga aagactatgt ttccccaaca
    43621 gaaattgata ctgataagaa attcgtcttc atcatcgatg aaatcaatcg tggggagatt
    43681 tctaagattt ttggcgaact ctttttctct atcgaccctg gctatcgtgg tgaaaaagga
    43741 agtgtttcta cccaatatgc aaatctacac gaaactgatg aaaagttcta tatccccgaa
    43801 aatgtttaca tcatcggaac tatgaatgat attgatcgtt cagtggatac ctttgatttt
    43861 gctatgcgtc gtcgttttcg ttttgttgaa gttactgccg agggtcaagt tggcatgttg
    43921 gataaagagc tgaatatcca tgcagaagaa gcaaaaattc gtctaagaaa cttgaacgct
    43981 gctatcgaaa atgttcagga attaaacagt cattatcata ttggaccaag ttattttctt
    44041 aagttgaagg atgtagattt tgactatgaa ttactctggt ctgattatat taagcctctc
    44101 ctagaagact acttgcgagg ttcttatgat gaggttgaaa ctttggaaac tttgaaaaaa
    44161 gcatttgaac tgacaaataa tgagcaaaaa gatcaggcag tagctgatga caatgaaggc
    44221 gatgaaaacg atgatgcgga ttactgataa tcaacacaag attattaaag aaaaatttgt
    44281 tgaagaatat cctaaactaa gcaatcttct tttagacaga accttggaaa gtctatccca
    44341 agatgaacgt attttcattt ttccaaatga tttgactcat actcctgatt tggataagga
    44401 ccaaaagatt tttgaaacag tcaatcagaa aatcaagaca gggaacgtga ttggttttct
    44461 tggatatggt caggaaagat taacgatttc ctcacgattt tctgatgaga gtaatgacca
    44521 ttttttgcat tatctcttaa acaaggttct tcatatcaat ctcactagtt tagatgttgc
    44581 tttgtctcgt gaagagaggc tttatcaact tttgatgtat ctcttcccca agtatctaca
    44641 agctgctatt cgaaaaggtc tttataagga ataccagaga ttttctcata acgacagtca
    44701 tgttaaggga gtgattgatg taagaaacca tctcaagaaa aatcttcctt tcacgggaaa
    44761 tattgcctac gcaacgagag agttcaccta tgataatccc ctcatgcagt tggtccgtca
    44821 cactattgaa tacattaaga atcagaaaag cattggtcaa ggggtactag ataatctctc
    44881 aactagtcgt gaaaacgtat ctgaaatcgt gcgtgtaacg ccctcttata aactagctga
    44941 tcgtgctaag attattcggg gaaatcaatc taaacctata cgtcatgcat actttcacga
    45001 gtacagaaac ttacaagaac tttgtctgat gatcctaaac caagaaaagc acggtttagg
    45061 gtatcaagat caaaaaatct atggtattct ctttgatgtt gcctggcttt gggaagagta
    45121 tgtttacacc ttgttgccaa aaggttttgt acatcccaga aataaggata agacggatgg
    45181 aatttcagta ttttctgttg ggaaacgaaa agtatatcca gatttttatg acagagaacg
    45241 aaagattgtt ctagatgcaa aatataaaaa actggaattg actgaaaaag gaatcaaccg
    45301 tgaggactta ttccagctga tttcctattc ttatatttta aaagctgaga aggctggact
    45361 gatttttcct agtatggagc agtcagtaaa tagtgaaata ggaaaagtag ctggctatgg
    45421 agctcaattg aagaagtggt ctattcgaat ccctcagaat gcctcattct atagtacatt
    45481 ttgtaaaatg atggaaaatt cagaagaaaa ttttaaagcg attattgatg aagaagtggg
    45541 gagaaaataa tttcccctct ttcttttatt tttaacacaa gtaaaacccg aacgatatat
    45601 tttaattcat aaaataattt gacaaaaact gtactttgat ttataataaa ttaaggaaac
    45661 gtcggaaaag gcgtagtgat gcaagagcat aggtaggtca ttacaaaaga aacgagacat
    45721 cgatatgtta aatgaatttc caatttttga ttacgaagat attcaattga ttccaaataa
    45781 atgtgtcatt aaaagccgtg cagaagcgga tacaagtgtc actttaggaa atcacacctt
    45841 taaactacct gttgtgccag cgaatatgca gacgattttg gatgaaaatg tagcagagca
    45901 actggctaaa ggtggttact tctacattat gcaccgtttt gatgaggcag gacgcattcc
    45961 ttttattaaa cgaatgcaca atcaagggct cattgcttct atctctgtcg gtgttaagga
    46021 ttatgagtat gattttgtta gccagctcaa ggctgatact cctgagtata tcactattga
    46081 tattgctcat ggtcatgcgg atagcgtgat ttctatgatt caacacatca agaaagaatt
    46141 gccagatacc tttgtcattg ctggaaatgt gggaacacca gaagctgtgc gtgaattgga
    46201 aaatgctggt gcggatgcta ctaaggtcgg aatcggtcct ggtaaggttt gtatcaccaa
    46261 ggttaagact ggttttggta caggtggttg gcagttggct gctctacgct ggtgtgccaa
    46321 ggctgcgcgt aaaccgatta tcgctgatgg aggaattcgt actcacggtg atattgccaa
    46381 gtctatccgc ttcggtgcta gcatgatcat gattggttcc ctctttgcag gacacattga
    46441 aagtccaggg aaaacgattg aagtcgatgg tgaacagttc aaagaatatt atggttcagc
    46501 ctcacaatat caaaaaggtg cttacaaaaa tgtggaaggc aaacgtatct tgcttcctgc
    46561 taaaggtcat ctgcaagaca ctttaactga gatggaacaa gaccttcaaa gtgctatttc
    46621 ttatgcaggt ggacgtcagg ttgctgacct taaacacgtt gattatgtga tcgtgaaaaa
    46681 ctccatctgg aatggggatg cttcccacta agacggggtc tttgaccaaa aaacttgtta
    46741 ttagagcaaa tttctgttat aataaaacaa gtttccaccc ttagtgtaat ggatatcacg
    46801 taagattccg gttcttgaga tgggggttcg attccctcag ggtggatgta aacatcctaa
    46861 aaagccttta atagggcttt tttctttatc ctgacccaaa tttgccgcta aaactgagaa
    46921 tctctgtcta aagaattccc aaatgctttc cagtcccgtt ttagagtgac tcagggggct
    46981 ttttttgata taataaaaag gactattatc agttagaaag aggttggtat gaaagaatta
    47041 caaactgtac taaagaatca ttttgcaatc gaatttgcag acaaaaattt actggaaact
    47101 gcctttactc atacgagtta tgccaatgag caccgcctct taaaaatttc acacaatgaa
    47161 cgcttggaat ttttaggaga cgctgttcta cagttattga tttcagaata tctatataaa
    47221 aaatatccta aaaagcctga aggtgaccta tcaaaactcc gtgctatgat tgtccgtgag
    47281 gagagtttag ctggttttgc gcgtgattgc cagtttgacc agtttatcaa gttgggtaaa
    47341 ggggaagaaa aatctggtgg tcgcaatcgt gacaccattc ttggtgatgc ctttgaagcc
    47401 tttcttggtg cccttctttt ggataaggat gtggccaagg tcaaggaatt tatctatcaa
    47461 gtcatgattc ctaaggttga agcaggcgaa tttgagatga ttacagacta taaaacccat
    47521 ctccaagagt tacttcaggt caatggtgat gtggctattc gttatcaggt gatttctgaa
    47581 acagggcctg ctcacgataa ggtctttgat gtagaagttc ttgttgaagg taagagcatc
    47641 ggtcaaggcc aaggtcgttc taagaaatta gcagagcagg aagctgccaa aaatgccgtt
    47701 gagaaggggc tggattcatg tatttaaagg aaatcgaaat tcaggggttc aagtcttttg
    47761 ctgataagac caaggtcgtt tttgaccaag gtgtgacggc agttgttgga cccaatggat
    47821 ctggaaagtc caatattaca gaaagtctgc gttgggcttt gggggagtct agtgtcaaga
    47881 gtctccgtgg gggcaagatg ccggatgtca tctttgctgg aaccgaaagt cgcaaaccgc
    47941 tcaattatgc ttctgtagtt gtgactctgg ataatcatga cggatttatc aaggatgcag
    48001 gtcaagaaat cagggtggaa cgccatatct atcgtagtgg agatagcgaa tacaagattg
    48061 acggcaagaa agtccgtctg cgtgatattc atgacctctt cttggatact ggattgggac
    48121 gagattcctt ctctattatt tcccaaggga aggttgagga gatttttaat tccaagcctg
    48181 aggaacgacg agctattttt gaagaagctg caggagtttt aaaatacaag actcgcagaa
    48241 aagaaactga gagtaaactg caacaaactc aggataatct agaccgctta gaggacatta
    48301 tctacgagtt ggataatcaa atcaagcctc ttgagaagca agctgagaat gcctgtaagt
    48361 ttttagactt ggaaggacaa cgtaaggcta tttatttaga cgttctggtt gctcaaatca
    48421 aggaaaataa ggcagaacta gagtcgacag aagaagagct ggctcaggtt caagaactct
    48481 tgatgagtta ttaccaaaag cgtgaaaaat tagaagaaga aaatcaaact cttaaaaagc
    48541 aacgccaaga tttacaggct gaaatggcca aagaccaagg cagtttgatg gacttgacta
    48601 gtctgattag tgatttagaa agaaaattag ccctatcgaa actggagtcc gagcaagtgg
    48661 ccttgaatca acaggaggca caagctcgtt tggctgcttt ggaggataag agaaattcac
    48721 tcagcaaaga aaagtctgat aaagaaagct ctttagctct gttagaggga aatctagtcc
    48781 aaaataatca aaaactcaat cgtttagaag ctgaattgct ggctttctca gacgatcctg
    48841 atcagatgat tgagctctta cgtgaacgct ttgtagctct tttacaagaa gaagcggatg
    48901 tctcaaacca gttgacccgt attgagaatg agttggaaaa tagtcgtcag ctttctcaaa
    48961 aacaagcaga tcaactagaa aagctgaaag agcaattagc tatagctaaa gagaaggcta
    49021 gtcagcaaaa ggaagagctt gaaactgcca aggagcaggt tcagaaatta ttggctgact
    49081 accaagctat tgccaaggag caagaggagc agaaaacttc ctatcaagct caacaaagcc
    49141 aactctttga ccgtctggat aatctcaaaa acaagcaggc cagagctcaa agtttggaaa
    49201 atatcctgag aaatcatagt aacttttatg caggtgttaa gagtgttctc caagaaaaag
    49261 atcgcctagg tgggattatt ggtgcagtca gtgagcatct gacctttgat atgcattatc
    49321 aaactgccct agaaattgcg cttggagcga gtagtcagca cattattgta gaagatgaga
    49381 atgcggcaac caaggctatt gacttcctta aacggaacag agccggtcgt gcaacctttc
    49441 ttcctttgac cactattaag gcgcgtacga tttctagtca gaaccaagat gctatcgctg
    49501 taagcccagg tttccttggg atggcagatg agttggtgac ttttgatact agactggaag
    49561 ccattttcaa gaacttgcta gctacgacgg ctatctttga taccgtagaa catgcgcgtg
    49621 aagctgctcg acaagttcgt tatcaggttc gtatggtgac attggatggg acagaattac
    49681 gcacgggtgg ttcctatgcg ggtggtgcca atcgccaaaa taacagtatt gtcatcaagc
    49741 cagaactgga gcaattacaa aaagaaattg ctgcagatga agcaagcttg ggttcagaag
    49801 aagcggcttt gaagaccttg caagaccaga tggctgcatt gacagaaaga ttagaagcca
    49861 tcaaatctca aggagagcag gcacgtattc aggagcaagg cttgtccctc gcttatcagc
    49921 aaactagtca gcaagttgaa gaactggaaa ctctttggaa actccaagaa gaggaaatag
    49981 atcgtctttc tgagggagat tggcaagcgg ataaggaaaa atgtcaagag agccttgcta
    50041 ctatcgccag tgaaaagcaa aatctggaag ctgagattga agaaattaag tctaataaaa
    50101 acgccatcca agaacgctat caaaatttgc aggaagaggt ggcgcaagct cgcttgctta
    50161 agacagaact gcaagggcaa aaacgttatg aagtagctga tattgagcgt ttaggcaagg
    50221 aattggacaa tcttaatatc gaacaagaag aaattcagcg catgctccaa gaaaaagttg
    50281 acaatcttga gaaggttgat acagaattgc tcagtcaaca ggcggaagaa tccaaaactc
    50341 agaaaacaaa tctccaacaa ggtttgattc gcaagcagtt tgagttggat gatatagaag
    50401 gtcaactgga tgatattgcc agtcacttgg atcaagctcg ccagcagaat gaggagtgga
    50461 ttcgcaagca aacacgtgct gaagccaaga aagaaaaggt cagcgagcgc ttgcgccatc
    50521 tacaaaatca attaacagac cagtaccaga ttagctatac tgaagcacta gaaaaggcac
    50581 atgaattgga aaacctcaat ctggcagagc aagaggtgca ggatttagag aaggctattc
    50641 gctcattggg acctgtcaac ttggaagcta ttgaccagta cgaagaagtt cacaaccgtc
    50701 tggactttct aaatagtcag cgagatgata ttttgtcagc gaaaaatctg ctccttgaaa
    50761 ccattacaga gatgaatgat gaggtcaagg aacgctttaa atcaaccttt gaagctattc
    50821 gtgagtcctt taaagtgacc ttcaagcaga tgtttggcgg aggtcaggca gacttgatat
    50881 tgactgaggg cgacctttta acagctggtg tggagatttc tgttcaacct ccaggtaaga
    50941 aaatccagtc gcttaacctc atgagtggtg gtgaaaaagc tctatcggct cttgccttgc
    51001 ttttctccat tattcgtgtc aagaccattc cttttgtcat cttggatgag gtggaagctg
    51061 cgctggatga agccaatgtt aaacgttttg gggattacct caaccgcttt gacaaggaca
    51121 gccagtttat cgttgtaacc caccgtaagg gaaccatggc agcggctgat tccatctatg
    51181 gagtgaccat gcaagaatcg ggtgtttcaa agattgtttc agttaagtta aaagatttag
    51241 aaagtattga aggatgacaa ttaaactagt agcaacggat atggacggaa ccttcctaga
    51301 tgggaatgga cgctttgata tggatcgtct caagtctctc ttggcttcct acaaggaaaa
    51361 agggatttac tttgcggtgg cttcgggtcg gggatttctg tctctggaaa aattatttgc
    51421 tgatgttcgt gatgacatta ttttcatcgc ggaaaatggc agtttggtag agtatcaagg
    51481 tcaggacttg tatgaagcga ctatgtctcg tgacttttat ctggcaactt ttgaaaagct
    51541 gaaaacgtca ccttatgtag atatcaataa actgctcttg acgggtaaga agggttcata
    51601 tgttctagat acggttgatg agacctattt gaaagtgagt cagcattata atgaaaatat
    51661 ccaaaaagta gcgagtttgg aagatatcac agatgacatt ttcaaattta caaccaactt
    51721 cacagaagaa acgctagaag ctggtgaagc ttgggttaat gaacatgtcc ctggtgttaa
    51781 ggccatgaca actggctttg aatctattga tattgttctg gactatgtcg ataagggtgt
    51841 agctattgtt gaattagcta aaaaacttgg tatcacaatg gatcaggtca tggcttttgg
    51901 agacaatctt aatgacttac atatgatgca ggttgtggga catcctgtag ctcctgaaaa
    51961 tgcacgacct gaaattttag aattagcaaa gactgtgatt ggtcaccata aggaacggtc
    52021 ggttatagct tatatggagg gcttataatg gcagatataa aattgattgc attggacttg
    52081 gacgggacct tgctgactac tgataaaagg ctgacggatc gtaccaagga aaccttgaaa
    52141 gctgcgcgtg atcgtggtat caaggtcgta ttgacaactg gtcgtccctt aaaagccatg
    52201 gacttctttc tccatgagtt agggactgac ggccatgaag atgagtatac cattactttt
    52261 aatggtggat tagttcagaa aaatacagga gaaatccttg ataaaacagt cttttcatat
    52321 gatgatgtgg cacgtttgta tgaagaaaca gagaaattat cactgcctct tgatgccatc
    52381 tcagaaggaa cagtttatca aatccaatcg gaccaagaaa gtctttatgc caaattcaat
    52441 ccagctttga cctttgttcc agtggacttt gaagacttat ctagtcaaat gacctacaac
    52501 aaatgcgtga ctgcctttgc tcaagaaccc ttggatgcag ccattcagaa gatttctcca
    52561 gaattgtttg accaatatga aatctttaaa tcacgtgaaa tgttgctaga atggtcacca
    52621 aagaatgttc ataaagcaac aggtttggca aaactaatca gccatcttgg aatcgaccaa
    52681 agtcaagtga tggcttgtgg tgacgaggcc aatgacctct ctatgattga atgggcaggt
    52741 cttggtgttg ctatgcaaaa cgctgtttct gaagtaaagg cagccgcaaa tgtagtgacg
    52801 ccgatgacca acgatgagga agctgtcgcc tgggctatcg aagaatatgt gctaaaggag
    52861 aactaagata tgggattgtt tgaccgtcta ttcggaaaaa aagaagaacc taaaatcgaa
    52921 gaagttgtaa aagaagctct ggaaaatctt gatttgtctg aagatgttga tcctaccttc
    52981 acagaagttg aggaagtttc tcaggaagaa gcagaggttg aaattgttga acaagctgtg
    53041 ttccaagaag aggaaatcca agacacagtt gaagaaagtc tggatttaga gccagttgta
    53101 gaagtttctc aaaaagaagt cgaagaattt ccacactcag aagaagggaa tactgagttt
    53161 ctagagacta tagaagaaaa taattctgaa gttcttgaag cagaaaggcc tcaagcagaa
    53221 gaaaccgttc aggaaaaata tgaccgcagt cttaagaaaa ctcgtacagg tttcggtgcc
    53281 cgcttgaatg ccttctttgc taacttccgc tctgttgacg aagaattttt cgaggaactg
    53341 gaagaactgc tgattatgag tgatgttggt gtccaagtcg cttctaactt aacggaggaa
    53401 ctacgttacg aagccaagct tgaaaatgcc aagaaacctg atgcacttcg tcgtgtcatc
    53461 attgagaaat tggttgagct ttatgaaaag gatggtagct acgatgaaag catccacttc
    53521 caagataact tgacagttat gctctttgtt ggtgtgaatg gtgttgggaa aacaacttct
    53581 atcggaaaac tagcccaccg ctacaaacga gctggtaaga aggtcatgct ggttgcagca
    53641 gataccttcc gtgcgggtgc agtagctcag ctagctgaat ggggccgacg agtagatgtt
    53701 ccagtagtaa ctggacctga aaaagctgat ccagccagcg tggtctttga tggtatggaa
    53761 cgtgccgtgg ctgaaggtat cgatattctc atgattgata ctgctggtcg tctgcaaaat
    53821 aaggataacc ttatggctga gttggaaaag attggtcgta ttatcaaacg tgttgtgcca
    53881 gaagcaccac atgaaacctt cttggcactt gatgcatcaa caggtcaaaa tgccctagta
    53941 caggccaaag aattttcgaa aatcacacct ttaacgggaa ttgttttgac taagattgat
    54001 ggaactgctc gaggaggtgt ggttctagcc attcgtgaag aactcaatat tcctgtaaaa
    54061 ttgattggtt ttggtgaaaa aatcgatgat attggagagt ttaactcaga aaactttatg
    54121 aaaggtctct tggaaggctt aatctaatca gaagcaaaaa tcctgcaagg tacaaacttg
    54181 caggattttt ttattcgaaa cgaccatctt gacgataggc gatatctggt tgccaagtcc
    54241 atttggcatc gaatttttca agtaggtcaa agctggcttg aggtcccatg cttccagctt
    54301 tatagtcatg aagtggggca ccattttcgg cccagagctc ttcaatacgg tcaatcaact
    54361 tccatgacgc accaacttca tcccagtggc taaagttagt tgagttgtta tttaggacat
    54421 cataaatcaa tttttcgtat ggttctggag aagcaccagt tgcagtcgca tctgtacggt
    54481 aatcaagtga gttaggagcc aagttaaatt cttctcctac ttgcttccca tttaggctaa
    54541 gagagaagcc ttctgttggt tgaatataga tggtcaaaat atttggagca agtggttctc
    54601 caaagataga atccatttgt ttaaagacga tgttgacatg ggttcctttt tcagtcagtc
    54661 gtttacctgt acggaaaaag aaaggaacac cacggaatcg atcgctgtct acaaagaagg
    54721 cacctgatgt aaaggtttca gttgttgatt ctggattcac atttggctcg ctacgataag
    54781 agatgtattt catgccatca atcttaccag agcggtattg cccacggata aagtgttctt
    54841 tgagttcttc atcagttgga tgatagaggt ttttaaagac cttaatcttt tcagcacgaa
    54901 tctcgtcttt tgtgaagctt gctggtttgt ccatggcgag gagcgaaaga agttgtagag
    54961 tgtggttttg gaccatgtca cggagggcac cggattggtc atagtagcca ccacgttctt
    55021 ctacacccaa gcgctccgca aaggtaattt gaacattgtc gataaaatcc ttgttccaaa
    55081 cgttttcaaa aatcaagttt gcaaagcgaa ctgcaaagat gctttggatc atttccttac
    55141 caagataatg gtcgatacgg aaaatttgtt cttcgtcaaa tgttgctagg agttcgtcat
    55201 tcaacttgtt tgcagttgcg taatctgtac caaatggttt ttcaacgatc aagcgctcaa
    55261 aacctttgcc atcgacaatg ttttcagatt tgaggtgttt ggcaatggtt ccaaagaact
    55321 gaggtgccat agacaagaag aagagcttat tgtgttcagc ttggtatttt tcattaagct
    55381 cagcttgtaa ttgacgcaaa gcaatataat gttccgaatc attgacatca tggctttgat
    55441 agtagaagtg gctagcaaat tcttgggctt gctcggtact atctgccaaa tcaaggatgg
    55501 actcgacaac tacagattca aaatattcct tactccaagg tctacgggca gttccaataa
    55561 cggcaaagtg cttggaaaga ttgccggatt tatatagtct aaaaagggaa gggtagagct
    55621 tgcgtttagc caggtctcca ctcgcaccga aaattgtaac aataacctta gatgacatct
    55681 agctacctaa tttctatttt tattcctagt cttgctaggt atgaggaaac ctcatttcat
    55741 aaacttaatt ctaacataat tttccgaaaa atcaaaaatt ccaatacgag gtagaaaaac
    55801 tgcaaggaaa tccttacagt ttgagtttag acgtttaaga ccttatctaa gaactctttc
    55861 agacgagggt gttgtgggtt atcaaagatt tggtcaggtg ttccgtcttc aaggaactcg
    55921 ccatctgcag taaagataac gcggttggca acctgacgag caaatcccat ctcatgggtt
    55981 acgataatca tggtcatgcc ttgctcagcc aattccttca taacgttaag tacgtctcca
    56041 accatctcag ggtcaagggc agaagttggt tcatcgaaga gcatgatgtc tggattcatt
    56101 gctaggccac gagcgatggc cacacgttgt ttttgaccac ctgataggct atctggattg
    56161 gcattagctt tatctgctag tccaaccttt tcaagcaact ccattcccaa ttcctcagct
    56221 tcttccttag tcatcaactt gtgctcaata ggagcaaagg tgatgttgtc caatacagac
    56281 atatgaggga agaggttgaa gtgttggaat accatgccga tattttcacg gacgtggtca
    56341 acattggttg ttttttcagt taaatcatag ccgttcacag tgatgtgacc gctagtgact
    56401 tcttctaaaa gattgaggct acggaggaaa gttgacttac cagaacctga aggaccgatg
    56461 atacaaacaa catctccttc atagaactta gtcgtaattc cttttaggac ttcatttttt
    56521 ccatagtgct tgtgtaaatc atttacatca atttttaatt ttgccattaa cgaatcctct
    56581 tttctaagcg tttcgctagt ctagtcaaaa gtgtgataat tacaagatag aagatagcaa
    56641 ggattgcata catcttgaaa ctttggtagt tacgagcaat gataatctta ccagtttgga
    56701 agagttcaac caaaccgata gcagatacga tagttgtatc tttaagagcg ataacgaatt
    56761 ggttgacaaa gtttggcaac atcaatttag ttgcttgtgg caagataatc ttacgcatgg
    56821 tttttccata agagataccc aagcttcggc tggcttccat ttggccaact ggaacggcct
    56881 gaataccacc acgaacgatt tcagcgatat aagcagccgc attgagtgag agggcaatgg
    56941 ttccagctac aaagtcgtta attgggcttt gttggcctgt gatagactcg atgaagtttg
    57001 gaattcccca gaagatgaag gctgcaagaa tcatcaatgg aataccacga ataacgtcaa
    57061 cgaaaatctc agagatgacg cgaagagatt tgtatgggct aacgctaaac ataccgaaga
    57121 taattccgat gacaatggca atagcaaatg agataagagc tagagcaaga gtgataccaa
    57181 gaccgctaag gagttgtttg tagttgtttt gaagcaagcc ccagagcgtt gtttcgtcaa
    57241 cagtacttgt tgaagcagtt gaagattcgc tagctaggta tttgtcaaga atcttttgga
    57301 attcaccgtt tgccttaagg tttgcaagtc cgttgttgaa catttcaatc agttctggat
    57361 ttgctccttt tttaacggca aaggctgttt caccgattgg agttccagag attggagttt
    57421 tcaatttttg accttggctg atagaatatt tgagaacagg ttcatcatcc ataacggcat
    57481 caatggcacc agtgtttaaa ctgtcataca ttgaagaacc atcagcaaag gttttgattt
    57541 tgtaaccgta tttgctttga ttttctgtta ggaaggtttg agaagcagtt ccgtttttaa
    57601 caccgactgt ctttcctttt agatcttcat aagaagcaat attgcttgat tctttgacac
    57661 caagaatggt attagcagtg tagtatgatt ctgagaagtc aaaagttgcc ttacgagcat
    57721 ctgtgacaga cataccagca atgataccat cggcttgacc agcttggaca gcactgatag
    57781 cagcatcaaa accagggttg gtgatttcaa tttcaaaacc ttggtcttta gcgattgcct
    57841 taatcaattc catatcaata ccagtgtatt ggttgcttga attttggaaa acaaaaggtg
    57901 caaaagaaga atcgctggca atgatatatt tagccttaac aggaatagct tttaatcctg
    57961 cgagagtagt tgtagttggc actgctgaag atgatgaagc agtccatttc ttgataattt
    58021 tatcaagact accatctttt ttcatttcag ccaaggcttg gttaaattca gtaaccaggt
    58081 gctcgtattt acttcctttt ttcacaccga aagcaaaact tcctacagct tcaccatcca
    58141 tttcaatatg gaggtcttga ccttggttaa tggcatattc gataacaggt ttgtcatcca
    58201 tcatggcatc gatggcacca gcactcaagc tgttgttcat taaatcacca gtgtcaaatg
    58261 ttttaatagt aaagccgtat ttatctttga ttgtttcaag gaaacgttga gcggcagttc
    58321 cgtttttaac accaacggtt ttgccagtta attggtcgta cttgctaatt ttgtgtgact
    58381 ttgtagtagc aatgacaact tttgtatcat agtaagtatc agacatggtg aagacttttt
    58441 cacgttcttt agtctttgtc atccctgcca tgatagcgtc ggcttgccca gcttgaaccg
    58501 cattgaccgc tgcgtcaaat ccaggatagg acatctgaat gttccagcct ttaatctcag
    58561 cgactttgtt aataatgtca acatcaattc ctttataagt ttgatctgaa tctttaaact
    58621 caaaaggtgc ataggcggta tcagaaacaa tcttaatcgt ttctgctttg gcaataccta
    58681 atgagaaaat tgggaataaa attagcaaaa atgctagaaa ttttttcttc atttttagtc
    58741 tccttttccg aatattctct cattatatca gaaaaagtaa aaaaaggcaa atttttatat
    58801 tttccgtgtc agaaaatata acattgattt ttccttttct ttcttgaatt gctattaaaa
    58861 agtgctataa taatagtata tatagaagaa aagaggacgg ggatatgaag aataaaagaa
    58921 tatttaaaga cttccaagct tcaaaaatga atttaaacat ttacacaagc cccttgttag
    58981 cctttgtttt tgtcttcata ggagagtttg tggcttatac tttatatggt attagtttgt
    59041 tagctctcat cggacttgct agaaattttg gagaggctgg tcaaaatctt gcaagctact
    59101 tgcagacctt gcatcagagc ttgacggata aaacaagtga ctttcgttta attttaggat
    59161 tactggcctt tggttttatt cttaacactg tgttcagatg gacaagaaaa gttgagaaaa
    59221 gacctattcg aaccttggga ttttatagag agaatttcct cagcaatctt ctgaaaggat
    59281 ttagtctagg cctggcactt tttcttctga ccttgttagg tttagtggtc ttaggtcaat
    59341 atcgtttgga atccattcac ttgaatcctt attctcttgc ctttgtcgtc tttactatcc
    59401 cattttggat tttacagggg acagcagaag aagtggtggc ccgtgcttgg ctacttcctc
    59461 aattggcctc aagaaccaat ctaaaactag ctattcttat atctagcctg ttctttaccc
    59521 tgcttcatat gggcaattct ggcctcaccc ctctatctct agtaaatctc tttttattcg
    59581 gagttgccat ggctctttac cttctcaaaa ctgatacagt ttggggtgtt gcaggtattc
    59641 atggtgcttg gaattttgct cagggtaatc tctttgggat tttagttagt ggtcaaccgt
    59701 caggaacgtc tctgatgacc tttttaccac aaggcaatca agattggcta tcaggtggtt
    59761 cttttggcat agaaggttcc attatgacaa gtctggtatt actactgctg attgtctatc
    59821 ttgctaataa attaaagaaa gaaaatgaaa ggatgtgact tcggtccgtc cttttcttcg
    59881 tgaaaatact ataagtatgc taaaatagga atagcacatg gagagaggat tcttatgatc
    59941 aatcacatta cagataatca atttaaacta gtatcaaaat atcaaccatc aggagatcaa
    60001 ccccaagcta tcgagcagtt ggtggataac attgaggggg gagaaaaagc tcagattctg
    60061 atgggggcga ctggaacagg gaagacctat actatgagtc aggtcatttc taaagtcaat
    60121 aaaccaactc tggttattgc ccacaataaa actctggctg gtcagctcta tggggagttt
    60181 aaggaatttt tccctgaaaa tgcagttgag tatttcgtat cctactatga ttattaccag
    60241 ccagaggcct atgtcccttc tagcgatacc tatattgaga aggatagttc tgtcaatgac
    60301 gagattgaca agcttcgcca ctcagctacc tcagcccttt tggagcgtaa tgatgttatt
    60361 gtcgtggcct cagtctcttg tatctatggt ttgggttcgc ccaaggaata cgctgatagt
    60421 gtcgttagtc tccgtcctgg tctagagatt tctcgtgata aactcttgaa tgacttggtc
    60481 gatattcagt ttgaacgcaa tgatattgat ttccaacgcg gaagatttcg cgttcgtggg
    60541 gatgtggtag agattttccc agcttcccga gatgaacatg cctttcgagt agaatttttt
    60601 ggagacgaaa ttgaccgtat tcgtgaagtt gaggctctga caggtcaggt gttgggagaa
    60661 gtggatcatt tagcgatttt cccagcgaca cactttgtga ccaatgacga ccacatggaa
    60721 gttgccattg caaagattca ggccgagttg gaagaacaat tagctgtctt tgaaaaggaa
    60781 ggtaaactgc ttgaagccca gcgtttgaaa cagcggacag agtatgatat cgaaatgttg
    60841 cgtgagatgg gctataccaa tggggttgaa aattattctc gccacatgga tggacggagc
    60901 gaaggagagc ctccttatac gcttctcgac ttcttcccag atgatttctt gattatgatt
    60961 gacgagagtc atatgaccat agggcaaatc aagggcatgt acaatggaga ccgttcgcgt
    61021 aaagaaatgc tggttaatta tggtttccgt ttgccgtctg ctttggacaa tcgtcctcta
    61081 cgtcgggagg agtttgagag tcacgttcat cagattgttt acgtttcagc gacacctggt
    61141 gactatgaaa atgaacagac cgagacagtg attgagcaaa tcattcgtcc aacgggactc
    61201 ttggatccag aggtggaagt ccgtccgact atgggacaga ttgatgacct cttgggtgaa
    61261 atcaatgccc gcgttgaaaa aaatgagcgt acctttatca caactttgac caagaaaatg
    61321 gcagaggact tgaccgacta cttcaaggaa atgggtatca aggtcaagta catgcactcg
    61381 gatatcaaga ccttggaacg gacggagatt atccgtgacc tgcgcttggg tgtctttgat
    61441 gtcttggtcg gaattaacct gctccgtgaa ggaattgacg ttcctgaagt gagcctcgta
    61501 gctattctcg atgctgacaa ggaaggtttc cttcgcaacg aacgtggact catccagact
    61561 attggacgtg ctgctcgtaa cagtgaaggc catgtcatca tgtatgcaga cacggttacc
    61621 cagtctatgc aacgtgctat cgatgaaact gcccgccgtc ggaaaattca gatggcctat
    61681 aatgaagagc atggtatcgt accacagaca atcaagaaag aaatccgtga cctgattgcc
    61741 gtgaccaagg cagttgctaa ggaagaggac aaggaagtcg acatcaatag cctcaacaaa
    61801 caagagcgca aagaactcgt caagaaacta gaaaaacaaa tgcaagaagc cgtcgaagtg
    61861 cttgactttg aactggcggc tcagatccgt gatatgatgt tggaagtcaa ggccttggat
    61921 taggggaata gtatgattta tttaagaaag ttaaagagag aagatttgat gtctttatgg
    61981 gaaatggctt attcacaact taatccagtt tggaaacagt atgatgctcc ctattatgat
    62041 gattatcagt atttttcaaa ttttaaagaa ttcgaactac aaaaatcaga atccatttta
    62101 agcaactcaa atcgccttgg tatttttgtt gatgataaac tagttgggac tgtttcgcgt
    62161 tattgggtat gtaaacaaac aagatggatg gaattgggaa ttggtattta tgataaaaaa
    62221 ttctggaaca ctggtattgg gaaagttgct atgttgcagt ggatagatag gacgtttcag
    62281 gattacttgg agttggagca tctgggtttg acaacttggt caggaaatct tggtatgatg
    62341 aaacttgctg aaaaattaag aatgaaaaaa gaagctcata ttccaaaagt tcgttattat
    62401 caaggtaaat attttgatag tattaaatat ggtattttga gagaagactg ggagaaaatg
    62461 aatgacggtt attatcaaat caatggaaac tcctgaagag atagaaggta aatcccttgt
    62521 tcactggcaa acgtggagag aggcttatga tgaccttttg cctgcagaat ttcaggagac
    62581 aatgacatta gaaagatgtc gattctttag tcaaaagtat ccagaaaata cattgattgc
    62641 gataggtgat ctgaaggtag ttggttttat cagttatggt aactttcgtg atgagactat
    62701 tcaagctggt gaaattattg ctttatatgt tttaaaagac tattacggaa aaggcatagc
    62761 acaaaagtta atgaaagcag ctttgactgc tctgaatcat ttttctgaaa ttttcttatg
    62821 ggtattgaaa gataacaagc gagccattgc tttctatcaa aaaatgggtt ttacttttga
    62881 tggacaagaa aagatacttg aacttggaaa gcctataaag gaaaaacgaa tggtattcta
    62941 ttctaaaata attttaaaaa gtagaagcta atggcactgg taccaagtct gaaaatttaa
    63001 taaattagaa agcgagtaaa tttatgtccc gttcccaatt aacgatttta acaaatattt
    63061 gtctgattga agaccttgaa actcagtgcg tggttatgca gtaccgtgct cctgaaacca
    63121 atcgctggtc tggttatgcc tttcctggag gtcatgtaga aaatggtgag gcttttgcgg
    63181 agtctgtcat tcgtgaaatc tacgaagaaa caggattgac tatccaaaat ccgcaactgg
    63241 taggtgttaa aaattggcct ttggatacag gggggcgcta cattgtcttt tgttacaagg
    63301 cgaccgagtt tactggaact cttcaatctt cagacgaggg agaagtttct tgggtgcaaa
    63361 aagaccagat tccaaacttg aatctggcct atgatatgct accattgatg gaaatgatgg
    63421 aagctcccga caagtcagag tttttctacc ctcgccgtac agaagacgat tgggaaaaga
    63481 aaatcttcta gtcttttact aaataaccta gctgatccaa ggcttcctcg atatagtgga
    63541 ggtcttgttg tgtttcggct tcgactaggt ggtaatggat gccatctgtc aattcagata
    63601 gaggtctaaa gtcagaatgc tcgacttgtt ctagaaaatg ttgcacatct ctgcgacaag
    63661 acagtttaag caaggtttca atttctccat aaacgggatg gtcaatcaag gtattctgga
    63721 catgcccacc attatcgaca atagcaagga gttcctgacc gatttcttca acttgatgtt
    63781 tcactttgaa aagtttgtga acataaggat tggtatcaat ttgcttatag atgtagccac
    63841 gattggtgga taggatagga gcgccatcgg ctctcaaaat tgcaatgtcc tgcacaatga
    63901 cctgacgtgt gacatgaaaa tgttccgcca aactttggcc attaagggct ttaggagctt
    63961 ctttcaagag ttggagcagg gcttgtttgc gatcttttgt catagctttt ccttttaacg
    64021 gcgttttcga agcactttat agacagctag tgctaatgta tagtctacca tactatggat
    64081 aattgtgcca aatccaacta gtacaaatag aacatagaac atgttttcta cattggtacc
    64141 cgaagttgcg taaaaaagga cacaggctaa tacttcagca agggcatgaa caacagccaa
    64201 aacaaaattg aaaacccagg aagattttgg tttatctagg gtatcgggga atttttgtag
    64261 gtaaagagct cctaaagcac caaaagatat atgggaaaaa gcccgaaaaa cgataaccat
    64321 gggatagcca gccatcaaaa atccaaaact agaggctagg atgacaaaaa ctgccatcaa
    64381 gggcgacaag aacatggcta taaaaatagc gatgtggctc cccaaagtat aggaagcagg
    64441 tggaatgaca atcttgaaag gcataacaat tggaatcaaa atcgcaatag ccgttaaaag
    64501 ggctgtcatt gtcataaatt gtgtcttttt ccgtgtattc acaagaatct cctttttaac
    64561 tgcatataca ctagtatggt acaataaacc agacaataaa gcaagaattt acttgggttt
    64621 atagatcatt ttttagttaa aagttatagt agattgaaac tagaatagta cacctctact
    64681 tctaaaacat tgttagaaat cgatttgact gtcctgatcg atttgtcctg ttcttatttc
    64741 gttttactat agtaaagatt tcattaaaaa gaaactgtat agagcaaaat ctccaccttc
    64801 aggtttgaaa gcggagattg tttttatttt ttcaaggttt gtagtcgtgg aacaatggct
    64861 agggttagaa ttgcagaaat gaccaattca gcaattgaat ttgttgagat aacggttgcc
    64921 agaagaagtt ggatatttcc attataaaca tttccaaata ggaagaagat tcctccaagg
    64981 acaaagatag tatttgtcaa ggaaccaagg gctccagcta aaatcagacc agtcttgttt
    65041 ttcatcagtt tatagactaa gtaaggagtt aaaccaatca aaatacgtgg gacgatggca
    65101 atgatagctg agtagatgtt tccgtttggt acgaagggag agaagaggta gcttgtcggt
    65161 agaatcgtaa tcgtgttaac cgtcaagcta agtagcccca tcaaaaatcc aagtgtaacc
    65221 ccaactcgtg gaccataaat aatgctggca ataatgacag gaatatgaac aatggtcggt
    65281 ttgattggaa atggaaaaag gttaaagata agtgagctca gaaagtgtat cacgagcatg
    65341 gtagcaaaaa agatagcaat gggtgcaata ttagagcgtt ttttcatcga gagtttcctt
    65401 tattctttct aaaataattg tgaggtcagc taaagctcct cgtccgtggt ctccacaagc
    65461 tagtagggat tccttaggag caatcagctg atagccgtag gtttctaatg ttttcagatt
    65521 attctgagtt actggatggt catacatttt tgtattcata gcaggagcta ttagtttggg
    65581 aatatgactt ggcagggcta gagctgtact ggttaccatg ttgtccgcaa atccgtgagc
    65641 tagttttgca atagtgttag cagttgcagg taccacgata aataaatctg ctttttttcc
    65701 aagttcgata tgattgacct gatcaggata gggttccttc atgacatcca agtggacagg
    65761 attctgtgag agtacctgta gtgtcaaagg ttggataaac tctgtagcag cctgagtcat
    65821 taagacagtg acttgatggc cttgtttttt tagagaactg actaaatctg ccgacttata
    65881 agaggcgatt gaacccgtta cagccaagag aatgtttgcc atagttttcc tttctaagaa
    65941 tgataggctt gaattttttc aaggaggagt tctgcaattt cttctttagt ctggactgtt
    66001 tgaagctgat ttttctcaac aaatatagct cggtgctgac ctgctgaaat ttgagtcagg
    66061 tcattcgcga tgattaaatc tgcttgattc ttgataagac tttttcgtgc aatgtcaacc
    66121 agatgatctt cggtaacatc aaccagcagt ttgaaaccaa tcagatgaat agtaggattc
    66181 cattccttga ctagggatat gattttgggt gtctttttaa ggaacaaaac ctgaacctca
    66241 tcagttgaag aaatcttggc ctgatgattc tgcttgctta aaaattcttt tagattggag
    66301 ctagcctgaa cttcctcaag ccctgtcata taaacaggag tgtagtcaga aacagccatt
    66361 gagtggatca agacctgata atcctgaaca cgttcttgca tttctattag aaggtccttg
    66421 gtattggtaa tttctcgaat acttaggtta ggatgaggct ctggcttcag agctcgtttt
    66481 gtcgtaatta aacaaacttc atgccctgca aaaagcaaag tctctgtgat aattttcccc
    66541 aagtgacctg tagaatggtt agtgatagag cggacgctat cgatagcttc actggtaccg
    66601 cccgatgtaa ctaaaatttt catagcacta ttgtacacaa aaataagcgg taagtaaaat
    66661 gaaagtgata aatttttggt aaaaacgaag atttactata gtttcaaact ataaaaccat
    66721 ataaaattta agaaaggact ctaaaagcct taaaaacaga gatatttacg aacgtttaga
    66781 gagttttagg atgttaaaaa tcttgttttg tgatataatg aattatcata taagaggtta
    66841 gaggaatttt gaatgaaaac agatattgaa atcgcacaga gtattgagtt gaagccaatt
    66901 gttgatgttg tagagaaact tggtatttct tatgacgatt tggagttgta cggaaagtac
    66961 aaggctaaac tcagctttga taaaattcgt gcagttgaga gcaatccagt cggtaaattg
    67021 atcttggtta ctgccatcaa cccaacacct gcaggtgaag gaaagtcgac acttaccatt
    67081 ggtcttgcgg atgccttgaa caagattggc aagaaaacca tgattgctat ccgcgaaccg
    67141 tctcttggtc cagtcatggg gatcaagggt ggtgctgctg gtggtgggta tgcacaagtt
    67201 ctgccaatgg aagacatcaa cctccacttt actggagata tgcatgctat tacaactgcc
    67261 aacaatgccc tttctgcctt gattgacaac cacttgcacc aagggaatga gctggaaatt
    67321 gatcaacgtc gtatcctctg gaaacgcgtt gtggacttga acgaccgtgc gctccgccat
    67381 gtgactgttg gtcttggtgg tcctctaaac ggtattccac gtgaggatgg ttttgatatt
    67441 acagttgctt cagaaatcat ggcaattctt tgcttggcaa cggacatcga ggacttgaaa
    67501 cgtcgtttgg cgaatatcgt tattggttat cgctatgacc gtacgcctgt ttctgtaggt
    67561 gatttgcagg ttgagggtgc cttggctttg attttgaagg atgctattaa gccaaacttg
    67621 gttcagacaa tttacggtac acctgccttt gtacacggtg gtccatttgc caatatcgct
    67681 catggctgta actctgtttt ggcgacgaca acagcccttc acttggctga ttacactgtt
    67741 actgaagctg gttttggtgc ggaccttggt gctgagaaat tccttgatat caagacacca
    67801 aacttgccaa catctccaga tgcagttgtt attgtcgcaa cccttcgtgc ccttaagatg
    67861 aatggtggtg tggctaaaga cgctctgact gaagaaaatg tagaggcagt tcgtgcaggt
    67921 tttgctaact tgaaacgcca cgttgaaaat atccgtaagt tcggtattcc agcagttgta
    67981 gctattaacg aatttgtatc tgatacagaa gctgaaattg cagccttaaa agaactctgt
    68041 gcctcaatcg atgtaccagt tgaattggct agtgtctggg ctgatggagc agaaggtgga
    68101 gtagcacttg ccgaaacagt tgttaagaca attgctgaaa atccagctaa ctataaacgt
    68161 ttgtacgata atgacctttc tgtccaagaa aagattgaaa aaattgtcac tgaaatctat
    68221 cgtggtagca aagtgaactt tgagaagaaa gctcaaacac aaattgctca aatcgttcaa
    68281 aacggttggg acaaattgcc aatctgtatg gctaaaactc aatacagttt ctcagacaat
    68341 ccaaatgcgc ttggagcacc agaaaacttt gaaattacca ttcgtgaatt ggtaccaaaa
    68401 ttaggtgcag gcttcatcgt tgccttaact ggtgatgtta tgaccatgcc aggtcttcca
    68461 aaacgtccag cagctctcaa catggatgtt gaaagcgatg gaactgtact aggcttgttc
    68521 tagtggattg aaattgactt taagtgagtt tggaaataat atccaagctc attttttctc
    68581 agactgcaag cagttcatca ataagattta tactcttcga aaatctcttc aaactacgtc
    68641 agcttcacct tgccgtaggt atatgatact gactctgtca gttctatcca caacctcaaa
    68701 acagtgtttt gagcaacctg cggctagctt cctagtttgc tctttgattt tcattgagta
    68761 taagtagata gaaaagttat atactatcta ttgaaaatat tataaatcag atacaaagac
    68821 aggtgaaacc ttctgtgtta tactagagat atgttagatt tgaaagaata cggtatcgtc
    68881 atgtggccgg aggagaaagt catttctttc cgtgagaaac ttctcgcttg gtatgatgaa
    68941 aacaaaagag atttgccttg gaggagaagt aaaaatcctt atcacatctg ggtatctgaa
    69001 atcatgcttc agcagaccag ggtggataca gttatccctt actacgaaag attcctggac
    69061 tggtttccaa ctgtcgaaag tctggcaact gcgcctgagg agagtttact gaaagcttgg
    69121 gagggcttgg gctattattc tcgagttcgc aatatgcagg ctgcagccca gcagattatg
    69181 actgactttg gtggccaatt tccaaatacc tatgaaggaa tttccagctt gaaagggatt
    69241 ggaccttaca cagcaggagc catttccagt attgctttta acttgcctga gccagctgta
    69301 gatggtaatg tcatgcgggt cttggcgcgt ctgtttgaag tcaaccacga tattgggatt
    69361 ccaagtaatc gaaaaatttt tcaggcaatg atggagatct tgattaatcc ggatcgtccg
    69421 ggtgatttta atcaagcctt gatggactta gggtctgata ttgagtctcc tgtaaatccc
    69481 agacctgaag aaagcccagt caaggacttt agtgcggcat atcagaatgg aaccatggac
    69541 cgttatccaa ttaaatctcc taagaaaaag ccggttccta tttatcttaa agccttagtt
    69601 gtgaaaaatt ctcaaggaca atttttactt gaaaaaaatg aaagcgaaaa gctcttggca
    69661 ggtttttggc atttcccctt tatagaagtt gataactttt cgcaagaaga gcagtttgac
    69721 ctctttcatc aggttgcgga agaaagtgtg aactttggcc ccagtccaga agagagtttc
    69781 cagcaggact atgacctaga tgttgattgg cttgatgttt gttttgatac agtccagcat
    69841 gtttttagtc atcgaaaatg gcatgtacag attgtagcag gtcaggtgag tgacttccat
    69901 gatttttcag atagggaagt tcgttggctt tcaccagaag aattcaagaa ttacccactt
    69961 gccaaacccc aacaaaaaat ctggcaggct tatgcacaag ccaacttaga cagtagccaa
    70021 gactagctat tgtgtcttct gactattttt tggtataata gtagagaaaa aggtgaacat
    70081 atgaaaaaaa tactaattgt agatgatgag aaaccaatct cggatattat caagtttaat
    70141 atgaccaagg aaggttacga agttgtaact gcttttaatg gtcgtgaagc gctagagcaa
    70201 tttgaagcag agcaaccaga tattattatt ctggatttga tgcttccaga aattgatggt
    70261 ttagaagttg ctaagaccat tcgtaagaca agcagtgtgc ccattcttat gctttcagcc
    70321 aaagatagtg aatttgataa ggttatcggt ttggaacttg gggcagatga ctatgtaacg
    70381 aaacccttct ccaatcgtga gttgcaggcg cgtgttaaag ctcttctgcg tcgttctcaa
    70441 cctatgccag tagatggtca ggaagcagat agtaaacctc aacctatcca aattggggat
    70501 ttagaaattg ttccagacgc ctacgtggct aaaaaatatg gcgaagaact agacttaacc
    70561 catcgtgaat ttgagctttt gtatcattta gcatcgcata caggtcaagt catcacgcgc
    70621 gaacacttgc ttgagactgt ctggggttat gactattttg gtgatgtccg tacagttgat
    70681 gtgactgtac gacgtctgcg tgagaagatt gaagatacgc ccagccgacc agagtatatc
    70741 ttgacgcgcc gtggagtagg gtattacatg agaaataatg cttgatttac tgaaacaaac
    70801 catttttacc agagatttta tctttatcct gattttgtta ggtttcatcc ttgttgtgac
    70861 cctcttatta ctggaaaata gacgtgataa tattcagttg aagcaaatca atcaaaaggt
    70921 taaagatttg attgcaggag attattccaa ggttcttgat atgcaaggtg ggtctgaaat
    70981 caccaatatt accaataatt tgaatgactt gtcggaggtt attcgtctca ctcaggaaaa
    71041 tctagaacaa gagagtaaga ggctaaatag tattctgttt tatatgacag atggggttct
    71101 tgcgaccaac cgtcggggtc agattatcat gattaacgat acagccaaga agcaactggg
    71161 gttggttaag gaagatgttc tgaatagaag cattttggaa ttgctcaaga tagaagaaaa
    71221 ctatgaattg cgtgatttga ttacccaaag tccagaattg ttgctagatt cccaagatat
    71281 caatggcgaa tatttgaacc ttcgagttcg ctttgccttg atacgtcgag agtctggctt
    71341 tatttcaggt ttggtggctg ttttgcatga tacgacggag caggagaagg aagaacgcga
    71401 acgaagactc tttgtttcca atgttagcca tgagttacgg actcctctga ctagcgtaaa
    71461 atcctatctt gaagccttgg atgagggggc tttgtgtgaa actgtagcac cagactttat
    71521 caaggtttct cttgatgaga ccaaccgtat gatgcgcatg gtgacggatc tcctccatct
    71581 ttcacgtatt gataatgcta ccagtcacct agatgtggaa ctgattaact tcactgcttt
    71641 tattaccttt atcctcaatc gttttgacaa gatgaaagga caggaaaagg agaaaaaata
    71701 tgagttggtg agagattatc ccatcaattc tatctggatg gaaattgata cagataagat
    71761 gacgcaggtt gtcgacaata ttttaaataa tgctattaag tattcgccag atgggggtaa
    71821 aatcactgtc agaatgaaga caactgaaga ccagatgatt ttatccattt ctgaccacgg
    71881 tttggggatt cctaagcagg atttaccacg tatctttgac cgtttctatc gtgtggatcg
    71941 tgctagaagt cgtgcgcaag gtggtacagg tctaggactg tctatcgcta aagaaattat
    72001 caaacaacat aagggcttta tttgggccaa gagtgaatac ggcaagggtt caacctttac
    72061 cattgtgctc ccttatgata aggatgcagt gaaagaagaa gtatgggagg atgaagtaga
    72121 agactagaat gagtgaaata ggctttaaat acagtatttt agcgtcgggt tccagtggaa
    72181 attcttttta tctggaaacc tcaaaaaaga agcttttagt agatgcaggc ttgtctggca
    72241 agaaaattac cagtctgcta gctgaaatta accgtaagcc agaagacctg gatgccatct
    72301 tgattaccca tgagcattca gatcatatcc atggagtagg cgttttggct cgcaagtatg
    72361 gtatggatct ttatgccaat gaaaagacct ggcaagctat ggaaaatagt aaatatcttg
    72421 gcaaggtgga ttcttcgcaa aagcatattt ttgaaatggg taaaaccaaa acctttggag
    72481 atatcgacat cgagagtttt ggtgtaagcc atgatgcagt cgcaccgcag ttctatcgct
    72541 ttatgaagga tgataagagt tttgtccttt tgacagatac aggttatgtc agtgaccgta
    72601 tggcgggcat tgtcgaaaat gcggatggct atcttatcga ggccaaccat gatgtagaga
    72661 ttttgcgatc aggttcttac gcttggcgac tcaaacaacg aatcctatct gaccttggtc
    72721 acctttctaa cgaggacggt gctgaagcta tgattcggac gctaggaaat cgtactaaga
    72781 agatttacct tgggcattta tctaaggaaa ataatatcaa ggaactggct catatgacca
    72841 tggtcaatca gctggctcaa gctgatctgg gagtcggagt agactttaag gtttatgata
    72901 cctcaccaga taccgcaaca ccattgacag agatatagaa agaacgctga gaaggtgttc
    72961 tttttatatt gactgaacac ctaaaaagta atacaatggt gttaccatta aaaaagggag
    73021 cacaaaagat gactactatt acattaaaag tttctgaagc tgataaaaca tttatgaaag
    73081 caatggctaa gtttgaagga gtttcccttt cggaacttat tcgcaccaaa actcttgaag
    73141 ccctagaaga tgaatacgat gctcgtgtgg cagatttagc ctatcaagag tatttagaag
    73201 acttggaaaa aggagttgaa cccattactt gggaagaaat gatgcatgat ttaggcttga
    73261 aggatgaata atttgtataa attagttcca acaagacgtt ttatcaagca attgaaaaaa
    73321 ttggaccgtt atacgcagaa gctaattaca aactatttac aaaccaatgt tttggaaggt
    73381 ccaagacgac acggaaaggc tttggttggt aatcgcgttg gtcaatggcg ctatagaatt
    73441 ggtaattatc gagttatcgt acaaattgta gatgatgaat tagtcgttgc tactctagaa
    73501 gttggtcatc ggagagatat ttattgaatt aaagctgagt aataacaata tagaaagtaa
    73561 ggagagtaaa aatttgaaga aaaaatggtt atttgcagat tattatgata caacaattat
    73621 tttacttgct ttaatctctg ttattctggt attacttgga tttgctgaga tgactgattt
    73681 ggacaatccg ccttatagta ttattgattt agtaatctgg ggtgtttttg taattgatta
    73741 tagttggcgc ttttttatta ctaaaagaaa atggcgcttt attcttgaaa atatttttga
    73801 tttattgacc attctccctt taaatgctat ttttacagtg tttcgattag gacgtatctt
    73861 ccgcttagca aggctgacaa aattactgaa actgactcgt ttacttagaa taattggact
    73921 tacaggtaaa ctagaaagaa aaattagtag attcttacga acaaatggat tgatttatat
    73981 cttgtatgtt aatatcttta ttgttctagt agggagttcg attttatccg ttgttgaaga
    74041 aaaatccttc tcagatagtc tttggtgggc tcttgtgaca gtaactactg ttggttatgg
    74101 tgatattgtt ccagtttccc tttttgggaa atggctagca gttttactga tgcttgtcgg
    74161 tattggaaca atagggatgc taacaagtgc tttgacgaac ttttttgtaa aggataatcc
    74221 agatgaacag ataaaacttg ataaactcaa agacgaatta tcgagctaaa gaatattaat
    74281 agagaaacaa tctgaaaaaa tcgaagaact acattgaatg ataaaagact tagttgaaaa
    74341 aatatcataa aggtgagaca aaataaaact tgattcgagg agaaatcaag taagttttga
    74401 cacaatagaa cgcatattat caggtataaa aacttgatac tatgcgtttt atagagaaat
    74461 aaaataaaat ctgaacaaat caattaggaa tttaaagcat tttataacaa cgttttagag
    74521 taatggggtg ctatttcaac ttcaacctac tataatacag aaaaaaatac agaaaaaaac
    74581 aactccctga tgattcaagg agttgtctat agttaaatta gtttttagaa gcttcttgga
    74641 attctggatt tttccatgct tcgtcaataa tagcttgcaa ttctttagca gatgcttgca
    74701 ttttttgagt ttctgcatcg ttcaatggaa tgtttactgg acgaacgata ccatgtgcac
    74761 caacaacagc tggttgaccg ataaagacat tctcaactcc gtattgacct tcttggaata
    74821 ctgaaagtgg aagtactgcg ttttcatcgt caaggattgc tttagtgata cgagcaaggg
    74881 ctactgcgat accgtagtat gttgcacctt ttttgttgat gattgtgtag gctgcatcac
    74941 gaacaccttc gaacaattca atcaattcag cttcttgaac attttgagtg tctttaagga
    75001 attcttcaag atttacacca gcgatgttag cgtgtgacca aacagcgaac tcagagtcac
    75061 cgtgttcacc catgatgtag gcgtgcactg aacgagcatc cacatccaat ttttcagcaa
    75121 gtgcttgacg gaaacgagct gagtcaagtg aagtacctga accgataacg cgttctttag
    75181 ggaaaccaga gaatttccaa gttgagtaag tcaaaacgtc aactgggtta gcagcaacaa
    75241 ggaagatacc tttgaaacca gattcaacaa cttgagttac gattgatttg ttgatagcaa
    75301 ggtttttacc tacaaggtca agacgagttt cacctggttt ttgaggtgca cctgcagtga
    75361 tcacaacaag gtcagcgtct gcacagtcag agtattgagc tgcatagatt tttttaggtg
    75421 aagtgaaggc aagggcgtga ctaaggtcaa gcgcatcacc aacagctttt tcatgcaatt
    75481 gtggaatttc gataattcca agctcttgtg caattccttg gttaacaagt gcaaaagcgt
    75541 aagatgaacc tacagcacca tcaccgacaa ggataacttt tttgtgttgt ttagttgaag
    75601 tcattgtttt aaacatctcc ttaattttat taggggattt tccctagaca acttcattct
    75661 atcactttta aaaaactttg tcacgaatat gccttatagt tctcgatgta aacgttttag
    75721 tggtttagag gctgaaatag atgggaattt atggtataat gttgttactt actaattgtg
    75781 aaatgaggca tttattaatg caggataaaa atttagtgaa tgtcaatctg acaaaggaga
    75841 tgaaggcaag ttttatcgac tacgccatga gtgttatcgt agcgcgagct cttcctgatg
    75901 ttcgagatgg cttaaaacct gttcaccgtc gcattctcta cggaatgaat gaattgggtg
    75961 tgaccccaga caaaccccat aaaaaatctg ctcgtattac aggggatgtc atgggtaaat
    76021 atcacccaca cggggattcc tctatttatg aagccatggt ccgtatggct caatggtgga
    76081 gctaccgtta catgcttgta gatggtcatg ggaattttgg ttccatggat ggagatagtg
    76141 ctgccgctca acgttatacc gaggcacgta tgagcaagat tgctctggaa atgcttcgtg
    76201 atatcaacaa aaatacagtt gatttcgttg ataactatga tgccaatgaa cgggaaccct
    76261 tggtcttgcc agcgcgtttt ccaaaccttt tggttaatgg agcaactggt atcgcggttg
    76321 ggatggcaac caatattcca cctcataatc tgggtgaaac cattgatgca gtgaagttgg
    76381 tcatggataa tcctgaagtg actaccaagg acttgatgga agtcttgcct ggaccagatt
    76441 ttccaactgg tgctcttgtc atggggaaat caggtatcca taaggcttat gaaacaggta
    76501 aaggttcgat tgtcctacgt tctcgtacag agattgaaac gactaagact ggtcgtgagc
    76561 gtatcgttgt aacagaattt ccttacatgg tcaataaaac caaggtgcat gagcatattg
    76621 ttcgcttggt tcaggaaaaa cgcattgagg gtatcacagc agtacgtgat gagtcaaacc
    76681 gtgaaggtgt tcgatttgtt attgaagtca agcgcgacgc ctcagccaat gttattctca
    76741 ataacctctt caaaatgacc caaatgcaaa ccaattttgg attcaatatg ctcgctatcc
    76801 aaaatggtat accgaaaatt ttgtctcttc gtcagatttt ggatgcttat attgagcacc
    76861 aaaaagaagt ggttgttcgt cgtacacgtt ttgataagga aaaagcggaa gcgcgcgctc
    76921 atatcttaga aggtctcttg attgcgctag accatatcga cgaagtgatt cgtatcatcc
    76981 gtgctagtga aacggatgcg gaagctcaag ctgagttgat gagcaagttt aagctttctg
    77041 aacgtcaaag tcaagctatc cttgatatgc gtcttcgtcg tttgacaggt ttggaacgcg
    77101 ataagattca atctgagtat gatgacctct tggctctgat tgcggattta gcagatattc
    77161 ttgctaagcc tgaacgtgtt tctcaaatta tcaaagacga attggatgaa gttaaacgta
    77221 aattttctga taaacgccgt acagagttga tggttggaca gatcttgagt ctcgaggatg
    77281 aggacttgat tgaagaatcg gatgtcttga ttaccctttc taacagaggc tacattaagc
    77341 gtttggatca ggacgagttc actgctcaaa aacgtggggg tcgtggtgtc caaggaacgg
    77401 gagtgaaaga tgatgacttt gttcgtgagt tagtgtcaac tagcacccat gatcatctgc
    77461 tcttcttcac aaacaaggga cgtgtctatc gtcttaaagg ttatgaaatt cctgagtatg
    77521 gtcggactgc caaagggcta ccagtagtca atctcttgaa attggatgaa gatgaaagta
    77581 ttcagacggt tatcaatgtt gagtctgatc gcagtgatga tgcttatctc ttctttacaa
    77641 cccgtcacgg tattgtgaag agaactagtg ttaaggagtt tgccaatatt cgtcaaaatg
    77701 gtctcaaagc gctgaattta aaggatgaag atgagttaat caatgtcttg ttgacagaag
    77761 gagatatgga tattatcatt ggtaccaagt ttggttatgc agttcgcttt aatcaatcag
    77821 ccgttcgtgg tatgagccgt atcgccactg gtgtgaaagg tgttaacctt cgtgaaggag
    77881 acacagttgt tggtgccagc ttgattactg atcaagatga ggttcttatt atcacagaaa
    77941 aaggatatgg taagcgtaca gtcgctactg aatacccaac aaaaggtcgt ggtggtaagg
    78001 gaatgcagac agctaaaatt accgaaaaaa atggcttgct ggccggtctt atgactgttc
    78061 aaggggatga ggatttgatg attatcactg atacaggtgt catgattcga accaatcttg
    78121 ccaatatttc acaaacagga cgtgcaacta tgggagttaa agtaatgcgc ctggatcaag
    78181 atgctcagat agtgactttc acaacggttg cggtggcaga aaaagaagaa gttgggacag
    78241 aaaacgaaac agaaggtgaa gcataatgtc tcaaaaaaat aataaaaaga aaaacaagcg
    78301 aaaaaatctg ctgacaaata tcctagcagg atttctgata ttactgtcac tggctttgat
    78361 ttttaatact caaattcgaa atattttcat agtctggaat accaataagt atcaagttag
    78421 ccaggtatca aaagaaaaat tagaagaaaa tcaggataca gaaggcaatt ttgactttga
    78481 ttctgtcaaa gctatctctt cggaagctgt tctaacttct caatgggatg ctcaaaaatt
    78541 accagttatt gggggaattg caattcctga attggaaatg aatttgccga tttttaaagg
    78601 acttgataat gttaatctct tctacggagc tggtacaatg aaacgcgagc aagtaatggg
    78661 agaaggaaat tatagtctag ctagtcacca tatctttggt gttgataatg ctaataaaat
    78721 gttattttct cctttagata atgctaaaaa tggcatgaag atttatctaa ccgataaaaa
    78781 taaagtttat acttatgaaa tacgtgaagt caaacgtgtg acaccggatc gtgttgatga
    78841 agttgatgat agagatgggg tcaatgaaat cacattagta acctgtgaag accttgctgc
    78901 tacagaacgt attattgtca aaggtgattt gaaagaaaca aaagattatt cacaaacatc
    78961 tgatgaaatt ctaacagctt tcaatcaacc atataaacaa ttttattaat acaaatcagt
    79021 gaaatcatgg atttcactga ttttttaaga ttttcataaa a
//
LOCUS       DAVHLA010000004        69906 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVHLA010000004 DAVHLA010000000
VERSION     DAVHLA010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 69906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 69906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69906
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.004"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(1..435)
                     /locus_tag="VVO77_000328"
                     /pseudo
     CDS             complement(1..435)
                     /locus_tag="VVO77_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(815..1675)
                     /locus_tag="VVO77_000329"
     CDS             complement(815..1675)
                     /locus_tag="VVO77_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEU5692401.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            complement(1691..2968)
                     /locus_tag="VVO77_000330"
     CDS             complement(1691..2968)
                     /locus_tag="VVO77_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU5692402.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIDRLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            complement(2961..3512)
                     /locus_tag="VVO77_000331"
     CDS             complement(2961..3512)
                     /locus_tag="VVO77_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU5692403.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLFIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            complement(3528..4787)
                     /locus_tag="VVO77_000332"
     CDS             complement(3528..4787)
                     /locus_tag="VVO77_000332"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEU5692404.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            complement(5837..5995)
                     /locus_tag="VVO77_000333"
     CDS             complement(5837..5995)
                     /locus_tag="VVO77_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692405.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            complement(6005..7315)
                     /gene="obgE"
                     /locus_tag="VVO77_000334"
     CDS             complement(6005..7315)
                     /gene="obgE"
                     /locus_tag="VVO77_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEU5692406.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLSENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            complement(7379..7513)
                     /locus_tag="VVO77_000335"
     CDS             complement(7379..7513)
                     /locus_tag="VVO77_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEU5692407.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            complement(7572..7748)
                     /locus_tag="VVO77_000336"
     CDS             complement(7572..7748)
                     /locus_tag="VVO77_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEU5692408.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            complement(7779..9104)
                     /locus_tag="VVO77_000337"
     CDS             complement(7779..9104)
                     /locus_tag="VVO77_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEU5692409.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGILIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGALYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFRTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            complement(9120..10163)
                     /gene="cpoA"
                     /locus_tag="VVO77_000338"
     CDS             complement(9120..10163)
                     /gene="cpoA"
                     /locus_tag="VVO77_000338"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEU5692410.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAVLKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            complement(10278..10607)
                     /locus_tag="VVO77_000339"
     CDS             complement(10278..10607)
                     /locus_tag="VVO77_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEU5692411.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            complement(10621..11730)
                     /gene="rpoD"
                     /locus_tag="VVO77_000340"
     CDS             complement(10621..11730)
                     /gene="rpoD"
                     /locus_tag="VVO77_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEU5692412.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            complement(11733..13493)
                     /gene="dnaG"
                     /locus_tag="VVO77_000341"
     CDS             complement(11733..13493)
                     /gene="dnaG"
                     /locus_tag="VVO77_000341"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEU5692413.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVPFIEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKTSEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            complement(13583..14341)
                     /locus_tag="VVO77_000342"
     CDS             complement(13583..14341)
                     /locus_tag="VVO77_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5692414.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            complement(14338..15204)
                     /locus_tag="VVO77_000343"
     CDS             complement(14338..15204)
                     /locus_tag="VVO77_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5692415.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            complement(15273..16277)
                     /locus_tag="VVO77_000344"
     CDS             complement(15273..16277)
                     /locus_tag="VVO77_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU5692416.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     IELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTIKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     misc_binding    complement(16390..16607)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(16690..19386)
                     /gene="ppc"
                     /locus_tag="VVO77_000345"
     CDS             complement(16690..19386)
                     /gene="ppc"
                     /locus_tag="VVO77_000345"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEU5692417.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     gene            complement(19406..20635)
                     /locus_tag="VVO77_000346"
     CDS             complement(19406..20635)
                     /locus_tag="VVO77_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEU5692418.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGITIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            complement(20779..21017)
                     /locus_tag="VVO77_000347"
                     /pseudo
     CDS             complement(20779..21017)
                     /locus_tag="VVO77_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(21420..22316)
                     /locus_tag="VVO77_000348"
     CDS             complement(21420..22316)
                     /locus_tag="VVO77_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEU5692419.1"
                     /translation="MTKISFEIQQQIIQCFGLCFHYKDTVVSFMQTSGVPNDLILKWK
                     SEPKFVWAKNVINELNKTENGRLIIRRIATEFYKMKNIPDEVQDRDRGLDALRKLKRL
                     IGDTQQNKVNETLNNSYHRSRQEMKIQLRQQLLQKIEELKTEYYSLFSSDNPQERGYR
                     LEKIVANLFRINDIDYHDSYRNRTNTQQLDGYFRFEGFDYLVEMKWEKNPVNSPKIAS
                     LKQKVDTKLTSTRGLFLSINGFRDEVIQDFSNKDAKILFMDGQELAYILENRISLYEA
                     LKVKIIGASKTGNPNVSIINQE"
     gene            complement(22341..25424)
                     /locus_tag="VVO77_000349"
     CDS             complement(22341..25424)
                     /locus_tag="VVO77_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU5692420.1"
                     /translation="MIEFGRRSLYFSKLVRSKAKMIEFDIPLESHLPISEDAQKSFLG
                     ALAIVADTARKYFEVYINRKSFNLQLKNQLHNAAEYFDALLVSGLGNSAEYQDYIAIL
                     GTTAYYLCDYNGSSRVMINYISDDIQLLEDCMTLIKVFIDVVTDELFLNHTPIEGKYS
                     SELNTLVESYRNYILSKTEFSIDIYRDLQDKVYRNGSDFSVIIVNCLLAVVCKKINSS
                     STKLLPEFSGLDFSLWQDYIQSTGSIKELWPSQIELGKQGIFSGKSGIVQMPTSSGKT
                     ASINLTLRSAFYSNRIDNALIVAPFRALCREIYRDINAHFVDENNVIVSEVFDLPEIP
                     QDFSIFNDGKKRVFILTPEKLLFLLRNHQSFIDEIGLCIFDEAHLFDDPSRGTNFELL
                     LSTVKQIFPKGIQKILISAVIPNSEAINRWFNEDGVIVSNNSIKTTEKRVAFSDLNGS
                     NEQLYFIDPITFEEEFFVPRTVSVSELEQLGKERKQKVFPELTNANDISIYYGTKLIN
                     NGGVGIFCGRKDTVNVILRRFIDLNNRNYDLTDFLKNSDRSEVEKIGNLIGQNLGYDS
                     VEYTCSQLGVFSHHSGIPMGIRIAIEYAFSKSKINNVVCTSTLAQGINLPIKYLIISS
                     VYQAGDAIKVRDFQNLIGRAGRAGKYTEGTIILTEPNIYKSPKNKWKKQNYKALLNPI
                     NTEGCQSNILSIIQFKSVVPTDYRFAPIKFDFWNLIKERFDSSVDYRTKINNILSKLK
                     RKNSLYFKDFNSKIDQIDNTLIAIENYIASMYATELETDSLAENTFGYFLGNEEEKEK
                     IKELFILIKSKIITSSVETEIIAKNSIGLYQSELLKEWVQENKTSILSCEKEEELLGV
                     LTKKIIDFSNNKEMRKLSIENLNYISQLWIKGISYFQILESCTEKSISIEKRGKSKPI
                     DMSDIISICDNGLGYETSMVLNAINNILEKLVGEELDVLTMLIKRLKYGLPLEKEINI
                     YELGFSDRIVVQVIGQEINSVSKNQIRNEIKQKSARLEDKLSDFPSYYTQIINEM"
     gene            complement(25421..26230)
                     /locus_tag="VVO77_000350"
     CDS             complement(25421..26230)
                     /locus_tag="VVO77_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1837 domain-containing protein"
                     /protein_id="HEU5692421.1"
                     /translation="MEKMHSYIKYLTQEDPIITDEGKQIEILHLDIQDDPEIFEDWAK
                     QFRRNYCSDDELAEMIGFMNISPKEYLENFKLPSDSGIGLSTMSGDFGEILVSDYLQY
                     IEEYVVPRTRYDSKVNKNTSTQGSDVLGYKQDSSNVSNDEVVVIEVKSSASDSSSSKA
                     KNKLQEAINHSDKDFERFSTSIVASYLRLKKSNSDQANVVERFLNITDKPFNVIYGAV
                     AVYSNQSYDIDVIKTVVSKNHRDFQKLRLLVIHSNELMKFIRELYSKASEV"
     gene            complement(26214..26990)
                     /locus_tag="VVO77_000351"
     CDS             complement(26214..26990)
                     /locus_tag="VVO77_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEU5692422.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQSIAILLGGQSGAG
                     KATIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQENGKDSVEYTKDFAGKMVESLV
                     TELSHLGYNLLIEGTLRTIDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYAINPNPARATPKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSCVYDSKENTT
                     SAAEVLQEYLFGKWSKVEEEMLKVGEERMRDMSKSNGKDA"
     gene            complement(26990..27466)
                     /locus_tag="VVO77_000352"
     CDS             complement(26990..27466)
                     /locus_tag="VVO77_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU5692423.1"
                     /translation="MIGKNIKSLRKTHDLTQHEFARIIGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIQTNIYLVENFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            complement(27911..28366)
                     /locus_tag="VVO77_000353"
     CDS             complement(27911..28366)
                     /locus_tag="VVO77_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692424.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNVIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
     gene            complement(28641..30380)
                     /locus_tag="VVO77_000354"
                     /pseudo
     CDS             complement(28641..30380)
                     /locus_tag="VVO77_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
     gene            complement(30543..31427)
                     /locus_tag="VVO77_000355"
     CDS             complement(30543..31427)
                     /locus_tag="VVO77_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEU5692425.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVIANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            complement(31539..32393)
                     /locus_tag="VVO77_000356"
     CDS             complement(31539..32393)
                     /locus_tag="VVO77_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEU5692426.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGMWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEATYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            complement(32451..33209)
                     /locus_tag="VVO77_000357"
     CDS             complement(32451..33209)
                     /locus_tag="VVO77_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEU5692427.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVYDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDVRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            complement(33270..33458)
                     /locus_tag="VVO77_000358"
     CDS             complement(33270..33458)
                     /locus_tag="VVO77_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEU5692428.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            complement(33780..34346)
                     /locus_tag="VVO77_000359"
     CDS             complement(33780..34346)
                     /locus_tag="VVO77_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692429.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPGENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            complement(34614..36293)
                     /locus_tag="VVO77_000360"
     CDS             complement(34614..36293)
                     /locus_tag="VVO77_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEU5692430.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSDKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGRIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGCKHRQMIRGHKCTFSKQIIEELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYKEKQSNGQWLKSITFKLPIIEENLNIGLDNDEQVECVSLLEKRS"
     gene            complement(36385..36546)
                     /locus_tag="VVO77_000361"
     CDS             complement(36385..36546)
                     /locus_tag="VVO77_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692431.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQDMKNSFD
                     MAKTQIETD"
     gene            complement(37230..37952)
                     /locus_tag="VVO77_000362"
     CDS             complement(37230..37952)
                     /locus_tag="VVO77_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HEU5692432.1"
                     /translation="MATNKRYYWIKLKEEFFTDKRIKRLRRISGGDTYTIIYLKLLLL
                     SLKDEGKLYYDGVESDFIKELALTIDETDDDVMVTVNYLINQGLLEVVTENDEYYLTE
                     IPNLIGSETAWAEKKRRYRQNKQRTLSLMSPTHVRQEIEKDIEIDKEREGEIDKKSTP
                     IFYGEFKNVRLSKEEYKNLKEKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEE
                     DKDKLRQKGLNKKMNYDVGESL"
     gene            complement(38126..39346)
                     /locus_tag="VVO77_000363"
     CDS             complement(38126..39346)
                     /locus_tag="VVO77_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000785359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="HEU5692433.1"
                     /translation="MADSFHFSVNIISRGKGKSAVASAAYISGEKIKNEWDGVTHDYT
                     RKEKILVKNIILPDHIPKEFNDKSTLWNKVEMAEKNSNAQLARQFIIGLPKELSLSEN
                     KNLVERYIKENLTSQGMIVDYAIHDESQDKNGNIHCHIMTIMRPINEKGEFLAKSKKE
                     YILDEKGEKVLNKNGKPKTRKVELTTWNDTGNVEKWRENFSDLCNKYLERAGAEKRVD
                     HRSFKRQNSDYLPTIHLGSAASAMERKGIETDKGNYNREIRKYNQLVKTIKEEIKTLK
                     GWIGNLLDNLSTAYEKFKDIERDKVIDNPKLFNLTNYLLTYSEIQKEKSKYLKGYAKT
                     NKEKYDFKKLTSAYSYLRKNNIETIGQLQTKIETLKSNSYRLNKKEKESIQKQIKKYK
                     DLSKNKDKTKEKGK"
     gene            complement(39656..39973)
                     /locus_tag="VVO77_000364"
     CDS             complement(39656..39973)
                     /locus_tag="VVO77_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000968321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3847 domain-containing protein"
                     /protein_id="HEU5692434.1"
                     /translation="MMASKRLSIEEQIEKKEESIKQLQNQKRQLKKKLNEQERKARNK
                     RLIEKGAVFESIFEESIDLTKDEFYKLIKTLNDEEIRLNIMEILEERIDDNVEKSSKD
                     EIT"
     gene            complement(40029..40454)
                     /locus_tag="VVO77_000365"
     CDS             complement(40029..40454)
                     /locus_tag="VVO77_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU5692435.1"
                     /translation="MPKRYLLDGKTPRISATNIDNGILGYYEDIDDKNYRVFENFISV
                     SFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTV
                     LPDIKIKLPIDSRGTPDWNYMERYIEDLKLKCNIANYNI"
     gene            complement(40842..41636)
                     /locus_tag="VVO77_000366"
     CDS             complement(40842..41636)
                     /locus_tag="VVO77_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5692436.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVNS"
     gene            complement(41636..42643)
                     /locus_tag="VVO77_000367"
     CDS             complement(41636..42643)
                     /locus_tag="VVO77_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU5692437.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            complement(42643..43650)
                     /locus_tag="VVO77_000368"
     CDS             complement(42643..43650)
                     /locus_tag="VVO77_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU5692438.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            complement(43640..44665)
                     /locus_tag="VVO77_000369"
     CDS             complement(43640..44665)
                     /locus_tag="VVO77_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HEU5692439.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            complement(45058..45276)
                     /locus_tag="VVO77_000370"
     CDS             complement(45058..45276)
                     /locus_tag="VVO77_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU5692440.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(45567..45800)
                     /locus_tag="VVO77_000371"
     CDS             complement(45567..45800)
                     /locus_tag="VVO77_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit M"
                     /protein_id="HEU5692441.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEVLELACWFRVIIVIEANSYV
                     NIRSSRLLPKFKTQKINSWCAAYSIHFNNGYCN"
     gene            complement(46014..47645)
                     /gene="rlmD"
                     /locus_tag="VVO77_000372"
     CDS             complement(46014..47645)
                     /gene="rlmD"
                     /locus_tag="VVO77_000372"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEU5692442.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVIIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMNLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(47719..48693)
                     /locus_tag="VVO77_000373"
     CDS             complement(47719..48693)
                     /locus_tag="VVO77_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEU5692443.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSAHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDVRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(48767..49381)
                     /gene="pmp23"
                     /locus_tag="VVO77_000374"
     CDS             complement(48767..49381)
                     /gene="pmp23"
                     /locus_tag="VVO77_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEU5692444.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(49381..50355)
                     /locus_tag="VVO77_000375"
     CDS             complement(49381..50355)
                     /locus_tag="VVO77_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEU5692445.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSSKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(50363..51619)
                     /locus_tag="VVO77_000376"
     CDS             complement(50363..51619)
                     /locus_tag="VVO77_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEU5692446.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPKTELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYESLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(51681..52112)
                     /locus_tag="VVO77_000377"
     CDS             complement(51681..52112)
                     /locus_tag="VVO77_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU5692447.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEEEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIC"
     gene            complement(52114..52716)
                     /locus_tag="VVO77_000378"
     CDS             complement(52114..52716)
                     /locus_tag="VVO77_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEU5692448.1"
                     /translation="MMDRIRQELEKGGAVVLPTETVYGLFSKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLSEISFEEA"
     gene            complement(52700..53539)
                     /gene="prmC"
                     /locus_tag="VVO77_000379"
     CDS             complement(52700..53539)
                     /gene="prmC"
                     /locus_tag="VVO77_000379"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEU5692449.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKRVRTLKDQFGQNRMVVVDD
                     GQD"
     gene            complement(53539..54618)
                     /gene="prfA"
                     /locus_tag="VVO77_000380"
     CDS             complement(53539..54618)
                     /gene="prfA"
                     /locus_tag="VVO77_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEU5692450.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEELAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(54615..55205)
                     /locus_tag="VVO77_000381"
     CDS             complement(54615..55205)
                     /locus_tag="VVO77_000381"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEU5692451.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            55329..55511
                     /locus_tag="VVO77_000382"
     CDS             55329..55511
                     /locus_tag="VVO77_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEU5692452.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            55648..57021
                     /gene="mnmE"
                     /locus_tag="VVO77_000383"
     CDS             55648..57021
                     /gene="mnmE"
                     /locus_tag="VVO77_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEU5692453.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(57068..58003)
                     /gene="dapA"
                     /locus_tag="VVO77_000384"
     CDS             complement(57068..58003)
                     /gene="dapA"
                     /locus_tag="VVO77_000384"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEU5692454.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAVLNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(58059..59135)
                     /locus_tag="VVO77_000385"
     CDS             complement(58059..59135)
                     /locus_tag="VVO77_000385"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEU5692455.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDMDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(59477..59549)
                     /locus_tag="VVO77_000386"
     tRNA            complement(59477..59549)
                     /locus_tag="VVO77_000386"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(59514..59516),aa:Thr,seq:ggt)
     gene            complement(59649..60158)
                     /locus_tag="VVO77_000387"
     CDS             complement(59649..60158)
                     /locus_tag="VVO77_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEU5692456.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(60156..60252)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            60281..60712
                     /locus_tag="VVO77_000388"
     CDS             60281..60712
                     /locus_tag="VVO77_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEU5692457.1"
                     /translation="MKKPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            60794..61171
                     /gene="mscL"
                     /locus_tag="VVO77_000389"
     CDS             60794..61171
                     /gene="mscL"
                     /locus_tag="VVO77_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEU5692458.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(61213..62307)
                     /gene="hemH"
                     /locus_tag="VVO77_000390"
     CDS             complement(61213..62307)
                     /gene="hemH"
                     /locus_tag="VVO77_000390"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEU5692459.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGMRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENIKMPYLIKKMLEKAGKLPKE"
     gene            62461..63684
                     /gene="pepT"
                     /locus_tag="VVO77_000391"
     CDS             62461..63684
                     /gene="pepT"
                     /locus_tag="VVO77_000391"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEU5692460.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTSLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(63720..64052)
                     /locus_tag="VVO77_000392"
     CDS             complement(63720..64052)
                     /locus_tag="VVO77_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001834557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692461.1"
                     /translation="MDALLDQLSANSKDKTALLESTKAILVLNHQIQSKASASEETSP
                     ARNAEANGDNTSAENQPNATAESNIETASDENKPSNTRDSKPAESTSENKTTESSTTT
                     GNQEKPVE"
     gene            complement(64057..64350)
                     /locus_tag="VVO77_000393"
     CDS             complement(64057..64350)
                     /locus_tag="VVO77_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692462.1"
                     /translation="MSKANQLLERIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDPQTLVLYQKLYDILMSLHFYLESNNGSDADF"
     gene            64315..64536
                     /locus_tag="VVO77_000394"
     CDS             64315..64536
                     /locus_tag="VVO77_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692463.1"
                     /translation="MDSFQELICLAQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(64673..64882)
                     /locus_tag="VVO77_000395"
                     /pseudo
     CDS             complement(64673..64882)
                     /locus_tag="VVO77_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809565.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="histidine triad protein"
     gene            complement(65003..65145)
                     /locus_tag="VVO77_000396"
                     /pseudo
     CDS             complement(65003..65145)
                     /locus_tag="VVO77_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262445.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(65179..65319)
                     /locus_tag="VVO77_000397"
     CDS             complement(65179..65319)
                     /locus_tag="VVO77_000397"
                     /inference="COORDINATES: protein motif:HMM:TIGR01363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEU5692464.1"
                     /translation="MLEITLKSPYQFAHILFQSTIVPHGGHYHFIPESDLSAGELAAA
                     KV"
     gene            complement(65363..65923)
                     /locus_tag="VVO77_000398"
                     /pseudo
     CDS             complement(65363..65923)
                     /locus_tag="VVO77_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(66149..69268)
                     /gene="phtE"
                     /locus_tag="VVO77_000399"
     CDS             complement(66149..69268)
                     /gene="phtE"
                     /locus_tag="VVO77_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HEU5692465.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNLADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
     gene            complement(69478..>69906)
                     /locus_tag="VVO77_000400"
     CDS             complement(69478..>69906)
                     /locus_tag="VVO77_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEU5692466.1"
                     /translation="DHVRKNKADQDSKPDEDKGHDEVSEPTHPESDEKENHAGLNPSA
                     DNLYKPSTDTEETEEEAEDTTDETEIPQVEHSVINAKIAEAEALLEKVTDSSIRQNAM
                     ETLTGLKSSLLLGTKDNNTISAEVDSLLALLKKSQPAPIQ"
BASE COUNT        20537 a        14395 c        11366 g        23608 t
ORIGIN      
        1 gacaatcgct tgagccttca tagcgtggca tttcttttta ccagaataat tcgctaattc
       61 tttttttagg gcgattgatt tttacttccg tcgcatcaat cattaccgtg tcctcagaac
      121 tgagaggagt tcttgaaatc gtaaaaccac tttgaacaag agttacttca acccattggc
      181 tccgacggag taagttgctt tcgtggatac caaaatcagc cgcaatttgt tcataagttc
      241 gatattctcg cactattgaa gagtggccat aagaaggtct tctaggctta atttaggttt
      301 tcgtccacct tttgcgtgtt taagttgata agctgttttt aatacagcta acatctcttc
      361 aaaagtggta cgctgaacac caacaagacg cttaaatcgt gcatcagtta gttgtttact
      421 tgcttcatca ttcatagaac tactatacca tattttgttt cgcaggaagt ataatataaa
      481 aaaataaatt taagattggc aatacaaacg ttaaacagaa ttccatttct ctttttagaa
      541 tcaaaacgac aatattgtgg aatctctaca ggaacaatag actgcgacac taaaatatcc
      601 tcccttagtt ttactttact aatagtatat aggaggagag ccctgaatcc tagacccttt
      661 gttatgatgc gcttacaaac aaagttggaa aaaatcttaa aagcagaaaa acgcatgata
      721 tcagccccta acacttgata caatgcgttt tattatgaaa agatctactg gattttttat
      781 caaaataaac ttccagtagt cttttcactt tttattaata agttccttct tcaccttggc
      841 tagtcaagat aacaggtcca tctttcgtaa tgacaaattg gtgttcatac tgacatgaca
      901 atccaccgtc aatggtctta tgcgcccaac cagttttcat atctgtatca atttcccaat
      961 cgcctgtatt gatcattggt tcaatggtta agaccattcc ttcacgaaga cggagtccac
     1021 gacctgcaat accatagtta ggaaccattg gttcttcgtg catagttggg ccaacaccat
     1081 gaccaaccaa atcacgcact acaccgtaac cacgactttc agcgtattct tgaatagccg
     1141 caccgatatc accgatacga tttccaacaa cagcttgctc aatacccttg tacatagctt
     1201 ctttggttac atccatcaag tttttgactt cttcggacgg tgtaccaaca gcataagccc
     1261 aacatgagtc tgctaaacca ccagaatagc tctgagtgta ttttttcatt tgttcaacat
     1321 tgttgaagtt taattttgag acattcaggt cggatttagc aatgggacct cccaaaacca
     1381 tatcaacttt gagcaaatca ccatctttca agatataatg acgagggaaa gcgtgagcca
     1441 cttcatcgtt aagagagcaa caggtagcat aaggatagtc catcatggca ccgtcaaccc
     1501 caatctgaag tggaaggaaa ttttcttctt tacaacgacg gcggacatat tcttcaactt
     1561 cccacatatc tacgcctggc ttaatcaaat cacgtaagcc tatatgaata cttgctagaa
     1621 aatcaccagc cttgtccata gcttcgattt cacgagctga ttttaatgtt atcatctttt
     1681 ctcctagttt ctaattaatt ttaacagtca catttgcttt tgaaacaatc tggtgaccat
     1741 gataaatatc gtaatcaatt atagctgacc gtctcgtatg atgaataatc cgtgcctgaa
     1801 tgcgcaatat atcatctatc tgaacagcct gcaaaaagta gatcagcatc tgctcgataa
     1861 tgagattgcg accactatta acaactaaat cttgggtcat gtgggtcaga atttctgcca
     1921 atacaccatt agccaaaact ccattttttt ctagcataaa gggttccact gtaatgacta
     1981 cttcatcatg gtgataagag agcttttgtc caatctgctc agaaaaagtt ggtagagccg
     2041 aaacttggga acggctcatc ttctccatga catctcgtcg cgtcacaacg ccaagcaaag
     2101 tttgattgct tcgaacaact ggtaccattt caaagtcttc tgcgatcatc cgttgactca
     2161 cattggcaat atttgtcgat aatccaacca aaaatagact acgagacata accttatcaa
     2221 ttgtcgtgct tggtgattta tcaccagcgt ctctcatggt tacaacgcca acaacgacct
     2281 gatgttgatt gataacaggg aaacggctgc tacgattctt acgaaccaag tccaaataat
     2341 ctttaactgt atctgtctct ctcagaaaac catactcatg actagggcga taaagtttct
     2401 caactgtcag aatatcagtc ttgatttgga catttgacaa ggctttattg atcatggtag
     2461 cgacggtaaa ggtatcatgc ttacttctta gaacaggaat ccctttttga ttggccagtt
     2521 taagcacatc atcatgaacc tgaaatcccc ctgtaaccag aactgcattt tcattttcca
     2581 aggctagcaa ctgaatacgg gttcggtctc cgacaatcaa gagcccccca tcatgaaggt
     2641 aagacaagat attttgttca gtcatggcac caattgaaaa cttactaaat tctctctcta
     2701 aaccttcttg cccagccaga acctcagaag aagtcacttc tgcaatttca gcaaacgtta
     2761 atctatctat agcaactttc tgggatttaa cacgaattgt tccacttcta ggacgggtct
     2821 ccacaattcc acggttttca gcttctttaa tagctcgata ggctgttcca tcactaactc
     2881 ctagatgatt cgaaatgcta cgaacactga cccttttacc tactggtaat tcctccaaat
     2941 agcttagaat ttcctgatgc ttactcattg aactctcctt ttacataccg aaattcaaga
     3001 taatcccgca tttttcttgt gtaacgatca cttcccttaa actgacggaa caaactaaat
     3061 ccagacttaa gagcaactct ttggctagct tcattttcaa ggtgggtaat gataaataat
     3121 tgttttaagc caaattcctc aaaagaaagc tgacaaattt ttctaacaac ctctgtcata
     3181 aatccttgcg accaagcatc ttttctcaaa aaatagccaa gctcagcttc ttttttgatt
     3241 tcatctaact tctcaaattt aatagaacca atcatttgtt gatttttctg gtcacaaatt
     3301 gcccacactc ccaaagggga cttcataaag taattggcca gtgcatattg actttcttcc
     3361 agacttgcct gcgttgggaa aataaattga agattttctg gatttgaagc tatctcgcgg
     3421 aagtcctgac tatcactaaa aaagaaagga cgcaaataca agcgatccgt ttcaaaaaaa
     3481 gaaaacattg ctaatttggt ccaaatattc ataaacacct ctacggttta atcctcaaca
     3541 agtctaatat ccgctcctaa attacgtaat ttttcgataa tatcagaata accacgtaag
     3601 ataaactcga tattggtaat ttcagtttta ccttcagcca taagcccagc aatgactagt
     3661 gcagccccag ctcttaagtc ggtcgcttta acactggccc cacgtaaatc acgtccaccc
     3721 gtgtacaaaa tatgaccatt tgttgtcgaa atatccgcat ccatctttgc tagttcaaaa
     3781 acatgattta cacgtttttc gtaaatcgta tcgacaattg taccacgacc attcgctctt
     3841 agtaaaagag gggtaagcgg ttgttgcaaa tcagttgcaa agcctgggta aggagctgtc
     3901 ttaatattga ttgctttcaa attagactgt tcctcgacaa aaatgctgtc ctcagataca
     3961 gtcattctca ctcccatttc ttccaactta gcaataaacc cttccaggtg ttcgtaaaga
     4021 acattattta tacgaattcc tttaccaact gcagcagcta aagatatata tgttccagct
     4081 tcaatacggt ctggaatcac ctgatgacgt gtcccatgta atctttcaac accatcaata
     4141 atgatgatat tagttcctgc cccacggata tgggcaccca tattattcaa gagagtagct
     4201 acatcaataa tctcaggttc acgggctgca ttttcaataa tagtacgacc atttgcttta
     4261 accgcagcaa tcatcgtatt aatcgttgct cccacactaa ccgtatccat gtaaatactt
     4321 gcaccatgaa gtcctgtatc tttagcagat aacttcatgt tatctccctc gtagctagca
     4381 gtggcaccca tagcttcaaa cgccttaagg tgtaagtcaa tcggacgagg accaagatca
     4441 catcctcccg gtagaccaac tgtcgcttca ccaaaacggc ctaagaggct cccataaaaa
     4501 tagtaagatg cacgaagact gttaatttta ccataaggca ttggaatatt ttgaacacct
     4561 cttgggtcaa tctccaatac atcgtcataa cgcttaacag tagctcccat caattccatg
     4621 atttcgacaa gactggctac atccgaaata tctggaacgc aatccaaagt caccacatca
     4681 tcagccaaga taatagctgg aattaaggca acgacactat ttttagcacc actaatagtg
     4741 atttcacctt gcagtggtaa tccaccattg ataacaattt ttctcattct aagttttcaa
     4801 tactctttca agatttctaa taaggtcttc aaaataaagt atatcataaa tttatccttt
     4861 tttccatcct tttcaatttt attggataaa tcagagttga cgagttagta actgaattac
     4921 taatactcaa tgaaaatcaa agatcaaact aggaaactag ccgcaggttg ctcaaaacac
     4981 tgttttgagg ttgtagatgg aactgacgta gtcagtatcc tacacatacg gcaaggcgat
     5041 attgacgtga tttgaagaga ttttcgaaga gtataatctt tctcgaatcg ctatttcccc
     5101 ttttttatcc cctaaaactg agtaggagct aagactagat ctcttatcta agtatcggaa
     5161 tacggctgtt caactaaatt ttagcaagaa cttctccccc ttctctcagt tcacagaagc
     5221 gttttataca taccgtccta tcagacaatc tattttaaag ataaccgtga ctcaggatca
     5281 cttctatctg tcgttttctc tttatagtga tagacctcac gggataagtc gtacatcttt
     5341 cctcgtgtat acaagatata aggacgttaa aagcttacag tgaaaataga aaatcttagt
     5401 acgaattcaa ttactctcgt gatttacgca tataggttac gactaccttt ttggacttta
     5461 gagtttgagg ccctcttatc cgctatatac gccttattat cacgttcctg ttcgtagagc
     5521 cacgatttcg ctatcccttc ttctgacaat tcttatttcc agcgtcagac ttaaaacggt
     5581 ctatccccag accattttaa tccgctacct cacgatagtc aggcttggga atcgctattt
     5641 gactcgccga gaactttgac atcagatata ctataacaaa ttgagataag aatcaaacaa
     5701 tttaattttg aaattcaaat caatttataa caatatttta gaagatatgc tgtgctattc
     5761 cagattcagt ttgctataca tgcctgtcgt accacaaaat cccgtgtctg atgaggcacg
     5821 ggatttttta gcttctttac tgagatggat tttccttttt agttcgtgcc aatctcaagg
     5881 cacgatttgg attgagacga ttaaatagtt cttccaattt cttttcattc caaacgtctg
     5941 cggcggaaac aaaattacca tccgcatctc ggaaagatat cggtttatct cccataccag
     6001 tctcctagtc tacaaattca aactcaaatt taccaatgcg gaccaaatcc ccatctttag
     6061 ctccacgcgc acgaagggct tcatcaaccc ccataccacg aagctgacgg gcaaatttca
     6121 tgacagattc atcacgatca aagttggtca tattaaagag tttcatgagt ttttcaccag
     6181 aaagtaccca tgtcgcatcg tcatcacgac taatttcaaa ggctttttct tcttcgtcaa
     6241 atccatagta agcttcttct tccatatcgg actcgtcgta gagcaaaaat tctggtgtct
     6301 tgtctaacaa ttcagctgta gcatctaaaa gtgttgccag accttgcttg gtcaatccag
     6361 aaattgggaa gatagctggt aactcttcaa attcatcata attttcagac aattttttct
     6421 taaattcttc aagattttcc tgactctcag gcatgtccat cttattagct acaataatct
     6481 gtggacgctc catgaggcga agattgtaag actccagctc tttattgata gctaggtaat
     6541 cctcatatgg atcacggcct tcgctagctg acatatcaat gatgtgaagg ataacacgtg
     6601 tacgctcgat gtgacggaga aactgagttc ccaaaccaac accttgacta gccccttcaa
     6661 tcaaacctgg caagtcggct actgcaaagg attcacctga ttgggtgcga accataccta
     6721 aatttggtac aatagtggta aagtggtagg caccaatttt aggcttagct gaggtaataa
     6781 cacttaaaag tgttgacttc cctacagatg ggaatcctac taaaccgaca tctgccaaga
     6841 tttttagttc caattgtaac tcacgttcct gacctggttc tccattttca gagatttccg
     6901 gtgcaggatt ttttggtgtc gcgaaacgaa tatttccacg tccaccacga ccaccgtggg
     6961 caacgataaa ttcttgccca tgttcaatca aatctgttaa aaccttgcca gtctccgcat
     7021 cacgaacagt cgtaccttgt ggtactcgaa ctctaaggtc ctcagcacca cgaccatgca
     7081 tccctttggt catccctttt tcaccagaat cagccttgaa atgacgattg tagcggaaat
     7141 ccatcaaggt acgtagtcct tcgtctacaa cgaagaccac attgcctcca cgaccaccat
     7201 caccacccca agggcctcca ttagggacat atttttcacg acgaaaggca accataccat
     7261 cgccaccatt accagccttg accttaatct tagctgtatc taaaaacata ctcattattt
     7321 cttctcactt taaaaaaggg ctgggaaatc ccagtcacta aattttcttg aatctatttt
     7381 atagattact gagggcacca attgcagttg caaaaattcc caataaactt gctactagca
     7441 tgataatcac gataaacaag gttattttct caaacatagt ttttttacga tttccattat
     7501 ctccaaatgc catttttctc tccttcgtta cattctattt tctattatct tagcatgaat
     7561 tgagctagtt ttcaatagtc agttgctact ggtgcgataa tccataaaat aatgtaagct
     7621 acaattccag ctccgtaaca gcaagtaaga acaccccaaa tgacttgaac gatagtcgga
     7681 tccatatcca gataatgggc caccccagca caaacacccg caatcttttt atcacgaccg
     7741 cttctcatta attgtttttt tcatagctgt tcctctttct attcttcatg gtctttccaa
     7801 tagtctctca tactgatcaa ctgtgttttt gaagccttca acatgcgtct agatcctttt
     7861 acaggtacag caaccacctg ttgcggaaga tacaaaactg tcctaaagat acgctgactg
     7921 accgtatcat ctttagccaa atctttctgg aagttatttg aaataatggc atccagataa
     7981 aactcatgca ctcgtttccc aaagttctca gctgaaatct catacaattt ctctgataag
     8041 gtatgctcat tcatgtctgg tgttgcaatc agggcttcca aaatagcacc agccaaatca
     8101 tgttctccat agtacaaggc tccaaacatt ttatcactga tgaggttgtt caaataagga
     8161 tttccgtgag caatgacagg tgttccactg gctaagcttt ccaagtaggt caaaccttgc
     8221 gtttcgcttg tcgatgccga aatgaagaaa tccgccgctt tatagtaaag agccgtctca
     8281 ctaggagcaa tcatccctgt aaagatgact gagtcttgaa tctctaggtt ctgggcttgc
     8341 tctttgaggt cattcagata agggccatcc ccagctacta ccagtttaac cttgtcttcc
     8401 tctttcagaa catcagcaaa ggctgctaaa actgcttgaa tatttttttc ataggagatt
     8461 ctcgaaagac taagcaacgt cttttcacca tcttgaatcc ctagtttact acgcagttct
     8521 ttcaaatttt cctgcttgat ttccggacgc tcaaacttgg ctaattcaat cccagtagga
     8581 atgacccgtt tttcaacctt gaccttataa tcagatagca agtcacggac aatctcacta
     8641 gggcaaataa ccccatccac atcatgcagg aaacctctaa ccagatactt gaccatactc
     8701 ggccggatca atatcccctt agcaatataa tggacatagt cttcatactg ggtgtgatag
     8761 gtatggatga ctggaatttt caattcacgc gcaatccaaa tccccaacag gccaagagaa
     8821 aattctgtct gagtatggat aatatctagc tgatactgtt tagcaatttc aagtgccttg
     8881 ctaaaacctc ggtaggcaaa gcgacgatcc ttaaaagcaa agaaaggaac acttggaatg
     8941 cggataattt gccaatcttc gtagcgattg acatccttat ctgtcgtcgt aaagataaaa
     9001 acagcatgtc cctgcttttc aagttctgtt ttcaaggttc gaatactggt cgcaacacca
     9061 gaaacctgag gaaaataggt atctgtaaat aaaccaattc gcatagatta cctcactttt
     9121 tactttctcc ctaaagcggc ttgtttctca taaaagtcca accagatttg taacagatgc
     9181 tcttcagaat actctctgga aatattctta gccttttctt tgagatcttt taagacagca
     9241 ggatttgctt gatattccaa aatagcctct ttcatctctt ctctacccgc tgtcgcccga
     9301 taatttccct ccaaaatcac cttatagaga tctaaatcac gcaacataat aggagcctca
     9361 caactcgcag cttctaaaat agtcatagga aagagctcat tgtaactagg caacaagaaa
     9421 agatccgcta gagcatacaa ttcgcgcatc cgctctggcg atacaatgcc tggaaaaatc
     9481 aaatttttag ggggattttc cataattttc ttatagtgtt cataaccatc tgtcatacca
     9541 ccaaaagaga agccaccagc ccagataaag gtaatctgag gcaattcctc agccagacgg
     9601 ataaagtcat caatcccttt acgtttctga acttgcccag cacctactac gataaactga
     9661 ttgtcactaa gaccaagatc tgtgcgcagt ctgactacct cttcttgtgg tagaggatgc
     9721 catttttcct tgttgacaaa gttaggaata taggtcactt tttcacgtgg aataccagct
     9781 gctaccaaat cctcaataaa cataggattg accacaacca agtgctccat ccggttgtaa
     9841 aaagaaaata catagcgttt cacaattccc tttaagaaaa atggaatttt caaacttcct
     9901 tcaagtgtag ctggcaagaa atgcacatag ccaatctttc tccctgagcg tttcttttgg
     9961 aaggttgata aataataggg aaaatcaatc gtatgaaagt gagtcacatc tgcctcgatt
    10021 ggaagatttt ctgtaacaat caattggtcc ttggcagcac ggtgaagaag acgaactaat
    10081 tcacggtaag cacctgaaac tccctgtcct gctactttct cacttgaact caacatattg
    10141 atgcgtaatt tctttttctc cataactact attatatcat tttctttgaa taaaatcagc
    10201 aaaagaaagg agagactaga ggaaaagagg ggaaatttcc tcgcttttcc tctagtctct
    10261 cacatgcttt tatatgttta cttaatgcct agggcaatgc gggcatagcg actcattttt
    10321 tcaactgtcc aggctggata ccagactaat ttaacctcag tatccgttac ttctggaacc
    10381 tctatcatag catcataaat ctggtctgtc aaaaggtctg ctaagggaca acccatagtt
    10441 gtcaaagtca tgtcaatctc tgtttgccct gtgtcaccgt caaaacgaat ctcatagatc
    10501 aaaccaagat tgacaatatc gattcccaac tcagggtcga tgacttcttc caaggctgtt
    10561 aaaatccgtg ttttgatgtt ttcaatttgc tcttctgtat aagccatatt ttcctcactc
    10621 ttagtcttca ataaaatcac gaagcggttt gctgcgactt ggttggcgta gttttctcaa
    10681 agcctttgct tcaatctgac ggatacgctc acgagttacg ttaaagactt tccccacatc
    10741 ttcaagtgtg cgcatttttc catcatctag tccaaaacgt agacgcagaa cattttcttc
    10801 acggtctgta agagtatcta agatttcatc caattgctca cgcaagacga tacgagtcgt
    10861 ataatccact ggattttcaa tcacttcatc ttcgataaag tctccaaggt ggctatcgtc
    10921 ctcttcaccg ataggagttt caagagatac tggttcttgg gcaatcttca agatttcacg
    10981 aaccttatca ggtgtcatat ccattcgttc agcaatctgt tctggtgtcg gatcttgccc
    11041 caattcttga aggagattcc gctgttcacg aaccaattta ttgatagttt caaccatgtg
    11101 aactgggata cggatggtac gagcttggtc cgcaatagca cgagtgatag cctgacgaat
    11161 ccaccaagtt gcataagttg aaaacttgaa ccctttagaa tagtcaaact tgtcaaccgc
    11221 cttcatcaag cccatatttc cttcttgaat caagtcaagg aactgcatgc cacgaccgac
    11281 atagcgtttg gcaatggaaa caaccaaacg aagattggct tccgcaagac gttgtttggc
    11341 ttcgatatcg ccagcttcaa cagccagtgc caactctttc tcctcttcat tggtcaagag
    11401 aggaacgacc cctatttctt tcaagtacat acggacaggg tcattgacct tagcagaagt
    11461 tgatccaatc aagtcctcat cgctgagttc tggttcttct tcattgctaa gaacacgcgc
    11521 acttggattt ccttcgttat ctgtgataga aatccctgca tcctgaatcc gttgcaagag
    11581 atcttcaatc ccatcagcgt ccaaggtaaa aggaataacc agacttgcat tgatttcatc
    11641 atctgttgct gtcccttttt gcttatgatt acggataaat tctgctacct gtacgtcaaa
    11701 tgttgttact tctttttgtt ttgttgccat tattactcca ttcttctctt ttgggaaatt
    11761 aaacgttcca attcttctag ggctgtatct gtatctccta catggctagc ttcctgcacc
    11821 ttctttttga ttctcatatt gtcctgattc aagagagcct tgtttcgagt catctctact
    11881 tcactaagtt cctgcggcga tatctcagca ggcaaatcct gagctaaaac ttggtaccaa
    11941 gctctttcaa cttcctctgt ctgctctgct aaaacttctg gaggaagatt tccatactgg
    12001 ccaagcaagt catataagac ctgaaattca ggtgtagcaa atgcaaagtc ttctcgcaaa
    12061 cggtaatcgt tcaaaacaag aggggattcc atcatccgat agagtagatg ggcttctgcc
    12121 ctcataatag ccgataactg cttggtgaca ggcatggtga ttggcgtcgg tctggaaatt
    12181 ctttccatgc gattctgcct ttgcacctga cgactctcat taacaatctg ctcaatctgg
    12241 gtataatcaa aggacgccag actgtcagct aaaatatgaa tatagctgtt ttgagcagcg
    12301 atggactttt cttgaacaat caagggagct attttttcaa taaactcaat ctgagcctgc
    12361 agattttcac tgttttcagg tttgtactga tgaatgtaga actcaatcgg actaatacga
    12421 gtttttgtta atagataggc caagtcttct ggaccatttt tttgtagata ctcatcagga
    12481 tccaagttat caggcatgct aacgatttgc acaggcatat caccaatttc atccaatgct
    12541 ttcaatatcg cggcttgccc agccttatct ccatcgtaaa caagaaccaa tttcttggtt
    12601 aaccttttca gatgctcaac atgctctcga ctcaaggccg ttcccatcga cgccacagca
    12661 ttttcgattc cagcccgata ggctgcaata acatccatga atccttccat caggtaaatc
    12721 tcactagttt ttccagaaga tttttttgcc ctatccatat gatataattc gtaacttttg
    12781 ttaaaaattg cagtcgatcg gctgttttta tacttagaag tttgtgaatc cgttttttgc
    12841 cagatacgac ctgagaaggc aatgaccttt ccttggtcat ttgtcagggg aaacataatg
    12901 cgattgtgaa aggtgtctac aaattgattg gcatccgaga gataaaacag gcctgaatcc
    12961 agtaaatcct cttcacgata ctgatcagac aaacgttgat agagatagtt tcgttctgga
    13021 ggtgctaaac caatccaaaa atgtttaagc acttcatctg tcaaaccccg ctgataaagg
    13081 taatttctgg cctcttcgcc catagtcgtt gtcatgagaa tagcatggta aaatttagcc
    13141 gcatcttcgt gcatatcata aagagcttgg tgaggcgagg ctggcttctg ttcactataa
    13201 agcggttttt caacctcaat cccgacacgc tgacctaaga tttggacagc ctctataaag
    13261 ggaacccctt ggtactcctc gatgaattta aagacatcac ctgagcgacc acaaccaaaa
    13321 cagtggtaaa actgcttgtc ctctacaacg ttgaaagaag gtgttttttc accatgaaaa
    13381 ggacagagcc ctagatagtt ccgtcctgcc ttttgtaaag aaatcacatc tcctatgact
    13441 tccacaatgt tggcattgtt tttgatttct tcaatgactt gtttgtcaac catacacaat
    13501 acctccatgt tatcatagtt tactttatat agtatacttt atttcagaaa aaaagtaaac
    13561 catttcactc attttcccta ctttattcaa agagttgata ataatcagag attttcattt
    13621 ttgctttttc ttcttggttt aaatcttgga taatccgtcc ttctttcatg acaatcaagc
    13681 gattgccgta tttgagagca tcttccatat gatgagtaat cataagggct gttagctgat
    13741 ctttcttaac aaattcatct gtcaattcca tcaaagcaac actagtcttt ggatccaggg
    13801 cagcagtatg ctcatctaac aggagtaatt caggtcgctt caaggttgcc atcaagagac
    13861 tcaaagcctg tctttgtcca cctgataaga actcaatcgg tgtattcaag tgtttctcaa
    13921 gaccatttcc tactttttca atggttgcct gaaattcatc cttatagcta gtcaagcgtc
    13981 gtggtaacaa tccacgcttc tcaccacgaa acttggcgat taaaagattt tcagcgaccg
    14041 tcatacgggg agctgtcccc atctttggat cttggaagac acgagacagg tacttggcac
    14101 gcttctcggg tgaaaactta gtgagatctt cacctaaaat acggatagtt ccactagtta
    14161 gtgataaggt ccctgctata gtgttaaaga gggttgattt tccagcacca tttccgccca
    14221 aaatcgtgat aaagtcccgt tcaaaaattt ctaaggaaac atcatttaaa ataatctttt
    14281 cttcatcaaa gccattttta acaattttgg ttgcattttt taattctaca attgctgtca
    14341 tttgcttaac ttggctcctt tcaagattgt ttgcttaaat gttggaatca tgaggcagac
    14401 tgctaaaatc aaggcactgt ataaacgaag gtaacttgta ttaaagccaa gtgcgataac
    14461 tgcccacact aaaaattgat aagcgataga acctacaacg atagtaacca aacgctctgc
    14521 caagctcaaa ctcttgaaaa taacttctcc aataatcaaa cttgcaagcc ccacaacgat
    14581 aaccccgatc cctcgagaca catcggcata gccttcttgc tgagcaatga gggcacctgc
    14641 aagggcaatc acaccatttg ataagaccaa gcccatgagc tccatgcgtc cagtatgaat
    14701 cccgaaactt ctagccatat caggattatc ccctgtagca atataggctt gtccgagttt
    14761 agtgtccaag aaaaagagca tgagagcaat aacaatgctc acaaagatga gacctgtcaa
    14821 gagttgattc aaatccgaat caaaaggcaa aacatcctga atttgcttgg ttccaagcag
    14881 gcctaaattc gcacgtccca taatcaagag catgattgag tgacaagaag tcatcaccaa
    14941 aatccctgag agcaaggttg ggatcttccc ttttgtataa agaaggcctg ctgccattcc
    15001 agccaaacaa cctgctccta cagcaacaag tgtcgctaaa aatgggttca cgcctttggt
    15061 tatcaaagtg acagcaacag ctcccccaag agggaaggaa ccttctgtcg tcatatctgg
    15121 aaagtttaaa atcctaaatg tcataaagat tcccagacct agaatagccc agacaaatcc
    15181 ttgagaaata atggaaacaa tcatatttta tttaatcctt tctatattca tctttttaaa
    15241 aaatgggaag agtctcctcc tccctacctt atttattcga tgacttgtcc tgcttctttg
    15301 agaacagact caggaatagt aatacctagt tcttgtgcta tttttttatt gatgactgac
    15361 ttaccagttg aaaagacatt gactggggta tcggctggtt ttgcaccttt caagacttgc
    15421 acaatcattt tacctgttgc cacaccaagg tcatgttggt caattacaac tgatgccaaa
    15481 ccacctactt ctaccatagc tgtcgcactg ggataaattg gtttcttaga actttgattg
    15541 ctagagacaa ccgttggaaa tcctgatgca atggtgttat caattggaac ccaaatagca
    15601 tctaccttga tagtcataac agtgacagtt gaggcaattt catttgttga aggaactgca
    15661 aatgtttcca ctgtcagacc tgctttttca gcataagcct taaattcttc aacctgtgtt
    15721 tttgaattgt cttcgctact tgagtaaaga gctccgattg ttttcacatt cggtgtcaga
    15781 gccttgatga gttcaatttg ttgttgagct ggattgtggt cagatacccc tgtaacgtta
    15841 ccacctggtt ttttcaaatc tttaaccaag ttagcaccaa ttgggtctgt aatagcggcc
    15901 atgataactg gtaggtcttt tgttgcacta gccaaccctt gggctgctgg tgttgcaata
    15961 ccaaccacaa ggtcattccc atttgcaacc aattgtttac tcattgtcgc aaccttactt
    16021 tgatcacctt ctgagttcat aaaatcaatt ttaacttgat catctttata tccttcttct
    16081 gcaagtccat cttggatccc tttataaatc aaatcaaggg atggatggct cacaaattga
    16141 agcacaccaa tcttggttat tttcttctca tccttattat tctgagcttc tgatttattc
    16201 attgaagaat aaatcaagct tcctgctact aagactgcta atgcagcaat aattccaatt
    16261 aaacgtttat ttttcattct gtttctcctt tttatttcct ttaacatatt tcacttatct
    16321 aaacaagcga cgccatcgtt ttctttccat actaacctcc atcaaaaaaa tcctcacaca
    16381 aaaaacttgt gtgaggacgt cgatgcgcgg taccacctca attataggga atttccctat
    16441 cgctcagtct cgcaataacg agatgcactg taaggtgtgc ttaccgaatt tttataattt
    16501 caaattctaa atagcattca gcccaatttt catcatcgcc acttatctgt tttcagctac
    16561 cacagactct ctaaaaagtt tgtatgatta cttttctgaa tggttaaatt atatcatttt
    16621 taaactactt gtcaatagtc tattagaatt tttttgatat tcacttttag cattcactct
    16681 tgaaaattat caacctgaat tacgcaatcc tgtcgcaatt ccgttgatgg tgatatgaat
    16741 caatcgttct tgatcactgg acaattctcc acgacgttgg cgtttaatca actctaactg
    16801 aatatagttg agaatattaa agtaaggcat acggtaatcc agactagctt ttagatatgg
    16861 attgtcagct aagagttcgt catgtccttc aatagccaag ataacgttct tagtaacttg
    16921 ccattcattt aaaatagtct catagatggc cttaacttgc tcgtcttcac aaagtttagc
    16981 atattcaaaa gcaatattca tatttgattt tgacaaaacc atatcaacat ttgaaagaag
    17041 cgattggaag aaaggccaat tttggtacat atctcgtaag atagcaatat tctctggatt
    17101 tttattgata aattccttga agcttgaacc aaccccgtac catccaggga acataacacg
    17161 actctgtgac catgagaata cccaagggat ggcacgcaaa ccaccgattt cagtaatagt
    17221 cttacgagcg gctggacgag aaccaatatt aaaacttgaa atagccttga ttggacttga
    17281 ctcgaagaaa taatcataga aatgctcatt accaaagacc aaatcacggt agatatcgta
    17341 actacggtcc actacttgat ccataatggc ttcataacga tttggggtat tggtatcgct
    17401 cttcttctga gtaatcatac ggttaatagc tgccgatact agcatttcaa ggttatagta
    17461 agcggcgtct ttgttaccgt atttattccc aattacttca ccctgctccg tcaagcggat
    17521 acgatccttg atagacttga gcggttgaga tgtaatggct tcataggttg gcccaccacc
    17581 acgaccgaca gtaccaccac gaccatggaa gaaggtaacc ttaacgccaa attcatctcc
    17641 aatagcagtc aattgttgtt gagccttgta gagggtccaa catgatgaca ggtaaccgcc
    17701 atctttatta ctgtcagagt agccaagcat gatttcttgg tagttatttc gtgagtcaat
    17761 ccattttttg gcaaggctaa gagaaagata ttttctcatt gtttcctctg aatgatccaa
    17821 gtcttcaatt gtttcaaaaa ggggaacaat ctgaacacgc gccctttccg tatccaccag
    17881 tcctacttct tttaacagaa tagctaattc tagcatatca gaaaggctgg ttgcatgtga
    17941 aatgatggtc tgacggatga catcatctcc caacttatct ttcaaaacac gagccgtctt
    18001 aaaaatagct aattcttttg ctaataattc tgatttttct gcgtgagtcg cagaaagaat
    18061 tcggggatct tcttctaatt ctttcaagag aaggtcacac ttttcttctt cgctcaactc
    18121 gctataacga gaatgaattc ctgctgattt caagagttct gccacacagg cttcatagac
    18181 gctagagtct tgtcgcatat caattgacgc taagtaaaaa ccaaatatct ctactgcctg
    18241 caataattcc acaaaatcac ctgaaatcaa ggactcaccc ttattttcta gtagagaatc
    18301 tcgaatggca atcaaatcct tgtagaaatc attggcggtt tcataacgag tcccaacttc
    18361 ttcatcctca atcagatagg ttttagttgc ctgaattttt gattgaatat caaacaaggc
    18421 acgacggtaa agctcttttt cgcggtaaat cgagttatcc ttggattgac gagccatttc
    18481 tctgacttgc ttgctgacgt tgacaatgct agttgaaaga gaaaattcac gataaagttg
    18541 gtaaatcttt ttatcatagt agttcatgat gacttcacac tgagtgagtg cagactgctt
    18601 caaggtcttt gctgtaacaa atggatttcc atcacggtca ccacctatcc acatacccat
    18661 ggtgattggt ttagcctgtt ttaaattcag accatgcgct tgcgctaagc gcttatactc
    18721 cgtcgtcaaa tgaggtacag ctttcaaaaa ggagctgtta taatattcca tagcattcgt
    18781 gatttcgtta gtcactttta attttttctc acgaatcatg tctgtctgca tgataatttc
    18841 gatgtaacga cgcaaatcat tgtaccattt atctttatta atcaacccca acttaacatc
    18901 acggtattta cgcaaaagac tatgaatatg atttgttaaa tccaacatac ttttgcgttg
    18961 cacttgtgtt ggatgggctg tcaaaacagg gacaacattc aagtgttcta ggatctcaac
    19021 ggcattttcc ttttctgcta ccaatttaat cgttgtagat aatttaccta aatagtcctg
    19081 atcaatatta ttttgatgat tgatttcata agctaaatcc acatcctctg aaatattaat
    19141 caaaagaggc aagatagaga aatagcgtga aatatagacc atttcatcat ttgataagct
    19201 agtcactaga cggtttagac cttgataatc ttcctgcgtt gataattctt tcaactgtat
    19261 tattttttca aaggtctctg gggcaagcat atttttagta atatcttcca gtaattctgt
    19321 tagaatcaag acttcttctt gcacaacact tttattacta taattttcta atttttgaag
    19381 agacataaac tatcctttct ttatcctact tcaacagaag gttcattggt tgattttcca
    19441 attctcggta caatttagcg cgtttttcac tggcatcaat atttaagaca aaggctactg
    19501 ccactgataa gactagaaga ctatttccac cctgggataa gaaggggaag gttactcctg
    19561 tagatggaat caagcccgaa atccctccga tattgacaaa tacctgaacc aacatcatcc
    19621 ctccgacacc gagtgcaacc atggcattga aaggattctc cgctcggata ccgaccaaga
    19681 taatccgcaa aatcatgaaa aataagagag ctaaaataag actggcacca acaaagccaa
    19741 attcttcaat cacgatagaa aagacaaagt ctgtatgagc ttctggcaaa taacctcgtt
    19801 tttcaatcga gtttccaaga cctagaccaa accaaccgcc attgaccatg gcaaaataag
    19861 aattagctaa ctggtgacct gcatcagcac gatcggcaaa aggattaaaa aaggcactaa
    19921 agcgcttggc tacatagcca aatactggaa tttttgaaaa ggtctcaaca ccgattaggc
    19981 tgatagtggt caagacaaag acagaagcgg cagatacgag cgccagaatg gttgaaaacc
    20041 agcgataagc gattccacta actgtataca taatcaagga aaccaagact aaaatagtcg
    20101 catttcctaa atcagggaaa attcccaaac ttccaatcag aactaggaga acgaatcgcc
    20161 aatcattaaa agcacgggga agccattgat tttgagtcaa aacttgaaaa tcataagtag
    20221 ctatttcttc ttgctgtttg gagaatcggt gagctaaata ccaaataata atgattttta
    20281 agtactcagc tggctgaata gttattcctg caaccgaaat ccaaccgtat gccccgttta
    20341 cggaaatacc aataaaacga gccaagaaca ataaaagcat ttctattaat ataactaaaa
    20401 tgattagtcg ctcatttctc aaaaaatcta gtctcaattt ataaattaag gcaatcagta
    20461 tcaaactaac aatccaaaag attccttggt ttcgaaccaa ctgcaaggcg ctcttgcctt
    20521 cttcaattaa aatagcactg gtggtcgaat agaccacaat caagcccaaa atagataaaa
    20581 gcaagtaggg aatcaagatg gaataattta ataagtgcct cttactaatc ttcatagtat
    20641 caccactcta ctaggataca gacaaatctg ttccaaattc cgttttattt tctagttttg
    20701 attgctatta taccattttt tcagaaagaa aaaaactctt accttacaat ccttcgaatt
    20761 ttactgtttt tacagaatta aggcagaatt tgaaatcgta aaaccatttt gaataagagt
    20821 tgcttcaatc cattgactcc gactaattat gttgctttcg tgaatgccaa aatcagccgc
    20881 aatttgttca taagtgtgct attctcgcat gtattgaata gttaccatga ggagatcgtc
    20941 taggcttaat ttggtttttc gtccaccttt tgcgcgttta cgttgcgttg ataagctgtt
    21001 tttaacacag ctaacatctc gtgcgctgaa cacctacaag gctcttgaaa cggctatcgc
    21061 ttaattgttt acttgcttca tcatccatag ttttattgta ttgtattttt gtttcgcagg
    21121 aagtctatta ttcctttcgt tccaaggttt ttacgctttt agcaacaagc ttacacactc
    21181 cacgtgatgc gtctgtggaa ctcaaaaggt tcggggaacc ttttgaggat taattgcgtt
    21241 tctctaacaa actcacacat ttaacgtggc atgactgatg aagtcatcat aagaatttca
    21301 cttgctgctc ttttacgatg gcagcctgaa cggtcagaag tatcattgta tatcatttgt
    21361 atcatggcat ataaagtatc gctctatttt attgatggtt ttaatatctc tcggaaaagt
    21421 tattcttgat taattataga aacatttgga ttgccagttt tagaagcacc aattatctta
    21481 acttttaaag cttcgtacaa actaattcta ttttctagaa tataagctaa ttcttgtcca
    21541 tccataaata aaattttagc atctttatta gaaaaatctt gtattacttc atctctaaaa
    21601 ccatttattg aaagaaacag tccccgagtc gaagttagtt ttgtatcaac tttttgtttt
    21661 aaagaagcta ttttcggaga atttactgga tttttttccc atttcatttc aactaaataa
    21721 tcaaaacctt caaacctaaa atagccatct aactgttgag tatttgttct atttctatac
    21781 gaatcatggt aatcaatatc attaattctg aataaattag caacaatttt ttctaaacga
    21841 tatcctcttt cttgaggatt atcacttgaa aatagcgaat aatactccgt ctttagttct
    21901 tcaatttttt gaaggagttg ttgcctgagt tgtattttca tttcctgtct ggaacgatga
    21961 taagaattat taagtgtttc gttaacctta ttctgttgag tatcacctat cagtcgcttt
    22021 aattttctta acgcatctaa tcctctatct ctatcttgaa cttcatcagg aatatttttc
    22081 atcttataaa attcagttgc tattcgtcta attatcaatc ttccattttc tgttttatta
    22141 agttcattta taacattttt cgcccaaaca aacttcggtt ccgatttcca ttttaatatt
    22201 aaatcatttg gaactcccga agtttgcata aatgaaacga cagtatcttt atagtgaaaa
    22261 cataatccaa aacattgaat aatttgttgt tggatttcaa aagatatttt agtcattttt
    22321 tctccttttt atcaacaata ttacatttca ttaattatct gtgtataata acttggaaaa
    22381 tcactcaatt tatcttctag tctagctgat ttctgtttga tttcatttct aatttgattc
    22441 ttacttacag aattaatctc ttgaccaata acttggacca caattctatc tgaaaaacct
    22501 aattcataga tattgatttc tttttccaga ggtagcccat atttcagcct ctttattaac
    22561 atagtcaata cgtccaattc ctctccaact agtttttcaa gaatattatt aatcgcattt
    22621 aaaaccattg atgtttcata ccctaatcca ttatcacaaa tagagattat gtcagacata
    22681 tcaattggtt ttgacttacc tcttttctca atactaattg atttttcagt acaactttcc
    22741 aatatttgaa aataagaaat ccccttaatc cagagttgag aaatataatt tagattttct
    22801 atacttagtt ttctcatctc tttgttattt gaaaaatcta ttattttctt ggttaaaaca
    22861 cctaataact cttcttcctt ctcacaagaa aggatagatg ttttattttc ctgaacccat
    22921 tcttttaata actcagattg atataatcca attgagtttt ttgcaattat ttcagtttct
    22981 actgaactgg taattatttt agattttatc aagataaata attcttttat tttttctttt
    23041 tcctcttcat tacctaagaa atatccaaat gtattttcag ctaaactatc agtctccaat
    23101 tcagtagcat acatagaagc aatataattt tcaattgcaa ttagggtatt atcaatctgg
    23161 tctatcttag aattaaaatc cttaaaataa agactgttct ttctttttaa ttttgataaa
    23221 atattattta tttttgttct gtagtctaca gaactgtcaa atctctcttt aatcaaattc
    23281 caaaaatcaa attttatagg agcgaatcga taatcagttg gaactactga tttaaactgt
    23341 ataatactga gaatattact ttgacaaccc tctgtattaa taggatttaa caatgcttta
    23401 tagttttgtt ttttccactt attttttggt gatttataaa tattgggctc tgttaaaatt
    23461 attgttcctt ctgtatattt tccagccctt cctgctctac ctatcaaatt ctgaaaatca
    23521 cgaactttta ttgcatctcc tgcttgatac acacttgaga taatcaagta tttaataggt
    23581 aagtttatac cttgtgctaa ggttgaagta catactacat tatttatttt actttttgaa
    23641 aaagcatact ctatagcaat gcgtatcccc ataggtatac ctgaatgatg tgaaaaaact
    23701 cctagctgac tacatgtata ttcaacacta tcatatccta aattttgacc aattaaattt
    23761 cctatttttt caacttcaga cctatctgag ttttttaaga aatcagttag atcataattt
    23821 ctattattta agtctataaa tcttcgtaaa ataacattga ccgtgtcttt tcttccacaa
    23881 aaaattccta ctccaccatt attaattagc ttagtcccat aataaatact tatatcattt
    23941 gcgtttgtca gttctggaaa aactttttgt ttgcgttctt ttccaagctg ctctaattca
    24001 ctaacactaa cagtacgtgg aacaaaaaat tcttcttcaa atgtaatagg atctatgaaa
    24061 tataattgct cattactccc gtttaaatca ctaaacgcaa ctcttttctc tgttgtttta
    24121 atcgaattat tagaaacaat tactccatct tcgttaaacc accgatttat agcttcacta
    24181 tttggtatta cagcagatat taaaatcttc tgtattcctt ttgggaaaat ttgtttaacc
    24241 gttgacaaca gtaattcaaa attggttcca cgacttggat catcaaaaag atgtgcttca
    24301 tcaaatatac aaagtcctat ttcatcaata aaactttgat gatttctcaa taaaaacaac
    24361 aatttctctg gagtaagtat aaaaactctt tttttaccat cattaaaaat tgagaaatcc
    24421 tgtggaatct ccggtaaatc aaaaacttca ctaacaatca cattattctc atcaacgaaa
    24481 tgtgcattaa tatctcgata tatttctcta cataatgctc taaaaggtgc aacaatcaat
    24541 gcattatcaa ttctatttga ataaaatgct gatcttaaag ttagattgat tgaggctgtt
    24601 ttacccgaac ttgttggcat ctgaacgatt ccagatttac ctgaaaaaat tccttgcttc
    24661 cctaattcga tttgagatgg ccaaagctcc tttatgcttc ctgttgattg tatataatcc
    24721 tgccataaag aaaaatctaa tcctgaaaat tcaggtaata atttcgttga tgaactattt
    24781 atttttttac atacaactgc taagagacaa tttacaataa ttacagaaaa atcgcttcca
    24841 ttcctatata ctttatcttg taaatctcta taaatatcta tagaaaactc agtttttgat
    24901 aaaatataat ttctatatga ttcaactaga gtatttaact cactagagta tttaccttct
    24961 attggcgtat gattcaaaaa gagttcatcc gttacaacgt caataaatac ttttataaga
    25021 gtcatacagt cttctaataa ctggatatca tccgatatat agttaatcat aactctcgaa
    25081 ctaccattat aatcgcatag ataataagct gtggtaccca atattgcaat atagtcttga
    25141 tattcagctg aatttcctaa tcctgacacc agcaatgcat caaaatattc agcagcattg
    25201 tgtaattgat tttttaattg taaattaaaa ctcttacgat tgatataaac ttcaaaatac
    25261 ttcctagcag tatctgcaac aattgctagt gccccaagaa acgatttttg agcatcctct
    25321 gaaattggta aatgactttc taaaggaata tcaaattcaa tcatctttgc ctttgaacgc
    25381 actaattttg aaaaatataa tgaccttctc ccaaattcta tcatacctca ctcgctttcg
    25441 aatagagttc tctaataaat ttcattaatt cattagaatg aatgaccaat agtcgtaatt
    25501 tctgaaaatc tctgtgattt tttgaaacta ctgtcttgat aacatcaata tcatatgatt
    25561 gattggagta gactgcaaca gctccataga ttacattaaa cggtttatcc gttatgttta
    25621 aaaatctttc tactacattt gcttgatcac tattagattt ctttaacctc aaatagctgg
    25681 ctacaattga ggttgaaaat cgttcaaaat ctttatcaga atgattaata gcttcttgaa
    25741 gcttattttt cgctttagag ctactagaat ctgatgcaga tgattttact tcaataacta
    25801 caacctcatc attcgacaca ttcgaagaat cttgcttata tcctagaaca tcacttcctt
    25861 gagttgaagt atttttattg actttactat cataacgagt cctaggaacc acatattctt
    25921 caatatactg aagataatca gatactaata tttctccaaa atctcctgac atcgttgaaa
    25981 ggccaatacc actatccgag ggtaatttaa aattttcaag atactcttta ggggagatat
    26041 tcataaaacc tatcatttca gcaagttcat catcagaaca ataatttctt ctgaattgtt
    26101 ttgcccaatc ttcaaaaatt tctgggtcat cttgaatatc taagtgaaga atctcaatct
    26161 gcttaccttc atcagtaata ataggatctt cttgagttag atactttata taactatgca
    26221 tcttttccat tacttttact catatccctc atccgttctt ctcccacctt caacatctct
    26281 tcctctacct tgctccattt tccgaagagg tattcttgta gcacttctgc tgctgaagtt
    26341 gtattttctt ttgaatcata tacacaactt ctatctcgtt ggtaaatttg aattctttca
    26401 aaaatagcta gttcttccaa ttgtcgtgta ttatcaacta gatgatttac aatgaaatca
    26461 tgatgttctt ttggagttgc gcgtgctgga tttggattga tagcatacag ttcttcgtat
    26521 cggataaggg tgctcagata ggacaattcg ggcttggttg caattaaggc taattgtacc
    26581 tcatacccct tattttttaa tagttgtgct gttttctttg gaacatcaat agttcgtaaa
    26641 gttccctcta tcaaaagatt gtatcccaaa tgactcaatt cggttactaa agactctacc
    26701 attttccctg caaaatcttt ggtgtattca acgctatctt tgccattttc ttgctgcagt
    26761 tctaaatagt gtggatgctg agaacgaaaa ctatcaccat ctatgataac aatatttcct
    26821 tgaaattctt tctgtttaat acgatgaatt gtagccttac cggcaccact ttgacctcca
    26881 agcaaaatcg ctatagattg tttactggac ttttttcctc ttgtcagtga acgaagattc
    26941 cttgctaaag catgtttgaa ttcactatca gtataatctt ggatttccat taagctacca
    27001 tccgcttttc agatatctct aacatacgtt caattccatc caaatagccg ctatatctct
    27061 ctatttcatc aaaattttct actaaataga tatttgtctg aatcaagtca gatagatcat
    27121 cactcattaa aatccaagga ttagattcat catcaatgct aattccctga ctatcttgat
    27181 aacgatagag tcgagataat agattagcac ctctttcttt cacaatttca attttcaaag
    27241 tcaattcata atcttcaaca ggattgagca ttttatcttc tcctacaata tcgacataag
    27301 atacattaaa cttctgacaa atgatgtcaa ttaattccgt agagactgaa ctagttccat
    27361 tttcataacg actcaagcta tttcgagaaa ttcctataat tcgtgcaaat tcgtgttgtg
    27421 ttaagtcatg tgttttacgt aaggatttta tgttttttcc aatcatggca aactccttta
    27481 tttttataaa tccattatag cataaaaaag cataacgcac caaaaatggt gcgttattga
    27541 ctgtttttct atcctaaact ttacttctat aaaagtcacc taaagagcca taaatattta
    27601 ttcttgtatt aattttttcg atgcgcaaac gatatctaca aatacatcta taacgattca
    27661 ccttttagga tttttattgt caaaattgcc tttatctaca aagacaaaat gcttataaaa
    27721 tagcttgaaa tcaaggatta tcaccttttt cgttgtagca acactccaca tgtgattatt
    27781 aggctattag caaagcgtat ccaatacctc aataaagtgt tgtttttact gatattttaa
    27841 ctatattgta tagtctacta tttaaatctc aattaggata ttttatagaa tacccaaaat
    27901 tcaacaataa ctaaaagtaa gattccattg tatttccttg ttggtctttc atatcacgaa
    27961 ttttattttt cagaatatta aagttacaaa tttcatctct aatatcgtta tccgctctgt
    28021 agccattaat catctcagtc agagttttcc ctttactacc attctttata gtagtattta
    28081 ctctttttat actgctttca aaaggctcat atgttttata cttaattact tcgtctttaa
    28141 aattaaataa aggtgtatcc ggcttagcat tccataaaat aatcaaccac attataacat
    28201 tataaagctg ctttgcagtt tcattccact tttcaggttg taaatttcca ctccctgtat
    28261 tgtcatattc ttgtctatta tttacatgag aatcacctac aagcggatta aaaagaggta
    28321 gccctttgtg attaattagt tctaaaaaat cccttgccgc acccatgcaa cactgaataa
    28381 cttccttctt gccatcaatt ttactctcag cgataaatac ataatattca tcttcaatag
    28441 ttgctcctgc atcactatgt ttttgttgat ttgctaacag cttaatatgt gctttaggct
    28501 aaacttcaaa atctctaaca attctttgtc ttgtttcatg tcctctacaa ttcatttaag
    28561 ttctccttta caagtttagt aactagcctt attatactat ataagatatg aaatgtacca
    28621 taatcttcat caactagttt ttagaaaatc acaaatccat ctggagagat gacaagctga
    28681 ttctccaatt cttggcaatt gcttgctagt actactgctt ctttctctaa aagataatct
    28741 tctgttgatt ggttgaatat tgctttgagg atccgtcctt cgtatttcca ttccagagct
    28801 actagatcag atttgatttc ttgaaggcta tacttgccat gcgaaatgat tactgacgcg
    28861 tatttccgaa tcttaatcag cctcttcata aagttcagca tatcattgtc acttgataca
    28921 cgttcccaag gcatacaacg acgacaatct ggatctggtc ctccagtcaa ggctagctcg
    28981 gttccgtaat aaatgcacgg tgttcctttt tgtaaaaaga gaaaggctaa ggctgattta
    29041 accagttgaa catcttcatt ggccgtccac aggattcgct ctgtatcatg tgaatccaag
    29101 agattaaaca tgacctctga aatctgctgc ttgtaataca tagactctcc attgatttca
    29161 tcgatgaact ggtctgtatt cttaattcct cgtaagaaat agtccttgat actatcagat
    29221 aaaggataat tcatgacggc atggaactca tctccattta gccaaggctg agatgtatgc
    29281 cagacttctc ctaggatata aagatcagga tttttagcta aaactgcctt acgaaaatcc
    29341 ttccagaact gatggtcaat ctcattagcc acatccaaac gccaagcatc gatattaaac
    29401 tcttcaatcc aataagtcgc aacctttaaa agataattct tgacctctgg attggctgta
    29461 tttagcttag gcatatagtc ctcgaaacca aaaacatgat agggtaagtc tctcttatta
    29521 actagctttt cagttgtcac tgggaattgt tgaatatgga accaatcctt ataagcagac
    29581 tgttcaccat ttttgacgac attttttcat tgaagagatt gcgaaccaat atgattaaat
    29641 accgcatcca gcatgacttt catgccacga tgatgcgctt gatccaccag ttcccgaaag
    29701 gtctccttgt ctccaaaatg acggtcaatt tcaaagtaat ctgtcgtatt gtacttgtga
    29761 ttgcttgtag attcaaagat gggacaaaga tatagtccag taatacccaa gtcttgcaag
    29821 taatccatat gatcaataat cccctgtaaa tcaccaccaa agaaatcatc actcttaggt
    29881 gtgacagatg aatcccagtc taaagtccct tctgggttta atagagcatt gccattggca
    29941 aatctttcag gaaatatctg ataccatacc gtatttgaaa ccccgtcagg aaccttgcag
    30001 gcatcaatct catgaagata aggcaactta aatccattcc caattgcatg aagattttct
    30061 agagaatttt ccacacaccc tttatcgcca tacaaaatat tttgaccttc tgtatctctg
    30121 agctcaaaga gatactggat acgtgcaaag tcaactgaca cttcaacctg ccaatggtca
    30181 aataaggtac cagaagttat cttgaccatt tcttttgtat cctgataaaa ctcctccata
    30241 aagataaaag ggtccccata gtgcaagttg atgctttcaa tgtccccttt cttagttcga
    30301 attcgaatat ggagtttctt atccttataa agataggcat actccgactc aggcccatgg
    30361 taaatagcac ttaattccat caatttgtct cctaaagtat tcattcaaat tttacgcaaa
    30421 cgttttcaaa ctcaataaat ccagtatact atttttgtaa actatttgca aggaatgtcc
    30481 gttgttaaag gaactatctt ttaaagtata caaaaagcct taaaaaaggc tttctctata
    30541 tactaatcct ctttcggttt tgaaaatact tctactcgct gagctaggac tttgatttct
    30601 acaggtaggt tatctgattt atctccgtca acatctgact ccaattcact atctgaagag
    30661 attttaatat tacgcgcttt gatatactcg atattatcat ttgcgataac atcccctttt
    30721 aataaatcag gaatgacgga taatttggag aatatagagg catctttcag aatcaaaatg
    30781 ttggcatagc cgtccttgtt ttcttcaaag attttcttat cagcgaagta atttgtcaaa
    30841 aggaccaaaa catggctagc ttcaccaaca taatttccat tttctgtctc aaccttaatg
    30901 ttaaagacct gatctgtcat gacagacttc atggtattta cagcataggt taaaataccg
    30961 aattttgttt tgtcctctat ttcaacattg tgaatcgcct caggcagaga accgatacta
    31021 aagatataac caaaatagtt gtcatttgct ttaccgatat caatcttatt ggttaaatca
    31081 aaatccagtt cgtcaattgc gccatcgatg tcttgattga tttccaaaag ttttgtaatg
    31141 aggttacccg taccgcctgg gataatccct aacttaggaa tgtagtctct ctcatcaata
    31201 cctgaaatga cttcattgac agttccatct ccaccaaaca caaccactgc atcatactgc
    31261 tcacgagaag cttcttcagc aaaatgtgtt gcatccagcg ctttttcggt aattttggtt
    31321 tcaacatatt caaagtattc ttttgcttta ttctccagct tttctttgta atccaaagcc
    31381 ttctcgccac cagaagtagg gttgataatt accattgctt ttttcattga ttttatcctt
    31441 aattttaaac agaaatgttt acatttcgtc gtatgcaagt aaatgtaatc ctattataca
    31501 atgaaaatac agaaaagaga aatctgacgt actggagatt aatacgcttt tattctattt
    31561 tcccatcgcc taactacatc ctttaagggt tcatccaagt aagaataggc cttatccttg
    31621 atccaatcag gaataccgta agttgcctct gctatgctac aagtgattgc tgcgagagta
    31681 tcactgtcgc caccaagtga gatggcattt cttatcgcat cttcgaagtc tctactttca
    31741 agaaaggcga taatggcttg agggacagtt tcctgacatg tttcgttaaa acgatagtta
    31801 ggacggattt catctaaagt ttgagataga ttgtaatcgt attctttttc tatataatcc
    31861 ttaattcgtc ttttacactc tgtaggattg tcgttaattg attgctcgta ctctctacaa
    31921 taaccaccaa agtaaaaacg acatagaaag atagcatcag ctgtagccat agcgcctttg
    31981 acaccttctg gatgattatg agttacctct gcagaaagac tcgtaagtcc tctagatgat
    32041 ggccacatac cagttttcgc ataaaaacca cagtccatga tccaagcaca tggagaaata
    32101 cgcatagctg atccattccc aaagctatta taaggttcac ggttatcgct gtttagccat
    32161 gcattaaacc gagcaccgta atcagcattc ggatacattc tgccatattt cttcatcgcg
    32221 tcaatgaaat cgtctttttg tccaccattc ataattgctt ctgcaacagc acaggtcata
    32281 accgtgtcat ctgtaaaaaa gcagtccttc cgaaataaag gaaagtcctt tgttttgata
    32341 ttgttccatt cgtaaacaga accgacaata tctccaataa ttgctccaag catcagattc
    32401 ctccttgttc attttgatgc tttttatatt ggttatctac catatttatt ttagaaaata
    32461 acatcctgtt ggattttaaa aatttcattt ttttcaaaat agggttttac catttctttc
    32521 cacctagctc tatgaaaatt gattgatttt aaaggagata ggccataatt tcccaatgca
    32581 taaccatcat ttacttcaac aacaagtgtt ctgccatcgc gagtaacacc gatatctagt
    32641 ccataagcta ttggcgcatc tttccaacat gatatcgctt catcaattac acttgcatca
    32701 aattgtgcat gataatcacc tgtatagggt cgaacatcta atacgcgaac atctaacaca
    32761 aaacaacgcc attcagctat gaattctaca acctcactaa tccatatagg atagtcgaaa
    32821 ggtagaccaa tacctattaa atcatgggtt ccattaacaa ctcttccagt aaagactttt
    32881 gaaccagctt taggcttaat aaattttccc caattatcag gtatattcac aatctctcct
    32941 aaaataccag cataaatctt tcgaccataa aactctttaa gctcaatagg atagtcataa
    33001 accggaacgt ttaagcccat catttttagt aatgctctag tctccattat ataatctaca
    33061 actatatctt cacttgttaa ctcttttatt tcagaaaaag attgatataa aataacttct
    33121 tctccttgta agtaggcacc tacttgagca ttgtatttat taattgaaac ctcacttggt
    33181 aatttacttt gtctaatata aacaaccatt tcatcactcc tatatcacta gtgttacacc
    33241 aatttgtaaa aataatagca attttgctct tatttttttg agtaaatagc ccccataata
    33301 tcatcgaaat aatcaacggt atttaggagt aattcaataa cctgggactt tgttagtcgc
    33361 attccccttc tatctctagc atcttctact aaattttcaa gtttctctag atttttatca
    33421 tccaaactaa tcattattct atttttatcg gttgccattt tcatcacctc aagttaattc
    33481 tatcacaggt gtaacacttg tgtcaactgg cttttataat acattagttt aaaagtggag
    33541 aggatttttt acacagtaac tttaaatctt tggtattaaa aaattttcac aatatttata
    33601 gaaataaaat ctgtctcaaa tcagttatca aatctagtat aaattatgag cggctactct
    33661 aatactttcc ctctaaacaa gaaaaagact tacactcaag gattttcttc ccccccttcg
    33721 ttataacgtt ttgactcttt tactagcaaa ggtatatact cacaaggaac tttggttgac
    33781 tattgaatct ctccaacttc ttctttaaca tatccttcta catcttcaat ctctacaaac
    33841 attgggtcta agtgacacaa gaaatgccaa acttcgatcc ctttttttct gtaaagaatc
    33901 gcttcaccgt cttcacttcc gaaaaagctt ctgtcgattt catatccgcg gctttctaag
    33961 aagtcttttg ctttacgata gttcgtttct cttgtttcga cataggcttt aacttcatgg
    34021 ttgttaacga catatgcatc aatttttgaa tatccttcga tcactctatc atttttgagg
    34081 gataaatttg aaatctcttt ccaaataatg tttacatttt ccccaggatc gaacataaat
    34141 ttagataaag gaacaatatt tccgttaaaa ataatttcca tataatccgg tatgttttta
    34201 ggattaaaat actccacttc aaaaccatct tctgtttcca gagtgtatcc cgggatttga
    34261 gctacaaagg ctttcccatc ttctatggaa tcaaatgcta ctaaatcttt agaataatca
    34321 ttttggtaca attccaatat aaccatcgat aatctctcca ttttcattat caggctaatg
    34381 taaataagca cgtcacctga ccaattcagg ctctctgtat catctcatca tatttcctac
    34441 ttactttacg agtcctatac ccagaacaca ccttatcgac cttcggtctc acctcgtcgc
    34501 attggctgaa catctacttt tactttgctg atgcttcaac tcgtacaagc agtgataccg
    34561 cctcagcgtg atgcgtcagt gggactcaaa aggttcgggg aaccttttga ggattaacta
    34621 cgtttctcta ataaacttac acattcaact tgttcatcat tgtccaaacc tatgttgaga
    34681 ttttcttcta taattggtag cttaaaagta atggatttta gccattgtcc gttagattgt
    34741 ttttctttat aaacttgaat ttcagaaatc aaagctgaaa ttaactgcct acgctctaca
    34801 tcattcatga ctttatagag cttatcaaaa tagatcagaa ccttatatat gttatctcct
    34861 gtaagctttt cagcttcaat agtctgtttc tttgctttcg catcaattag tgatgattct
    34921 aattcatcta ttttgtcata catacgatat agtctatcat ctaaatcctg tttccttctc
    34981 ttataatgct tatcttcaac atctaaatta tctatttcct caattagctt aaactttgta
    35041 gaatgactct ttctcaattc cttttggtaa ttatctattt ctttttctat ttcagaggta
    35101 tccaccttca tgttgatttt ttcttgcatc atagaagcaa atttcggatt acttactatc
    35161 ttgacaatca cctctgcaac agcatcatct aacaattctt ctataatttg cttactgaat
    35221 gtacacttat gacctcttat catctgccta tgtttacaac catagtaata aaaatcttta
    35281 tactttgtgc catctttctt tttcttgata cacttgttcc caaacattcc cactccacat
    35341 atcgggcatt ttacaattcc agaaagcaag tgtgtgcgtg tatcttttcc tttattcaca
    35401 tgctcatatt tctttgcttg agattttagc ttaacctgag cagcttgcca aacttcatcg
    35461 gaaactatag cttcatgtat cccttcagat attagatatt catcttgttc aacctgctta
    35521 tattcatttc ttgtaccatg aactttttct aaagttcttc ttccaaatgc tattttccca
    35581 ttatatacag gattctttaa tatctttctt ataagacctg catcaaacaa aggattctta
    35641 ccattctgtc ttgggatttt tctaattcca tgattctcta agtatttaga tatcccattg
    35701 gctcctatcg tagtatttac atactggtcg aaaatcgttc ttattgcaac tgcctcttcc
    35761 tcatttataa acagcttgcc gtcttcaagt ttatatccat acggagcaaa gccaccattc
    35821 cattttcctt cccttgcttt ttgaatgcga ccttccattg tttgaatacg gatgttttct
    35881 ctttctattt cagccacagc tgataaaaca gaaatcatta gtttcccagc atctttagat
    35941 gaatcaatgc catcttcaac gcagataaga ttaactccat aatcctgcat tatctgaagt
    36001 gtagaaagaa catcagcggc atttcttgca aatcttgata acttaaacac aagaacaaaa
    36061 gatactccat cttttccaga ttttatatct tccatcattc gattgaactg tattctacct
    36121 tcaatagact tgtcagactt cccggcatct tcatactctc caacaatttc ataatcgttg
    36181 taaatagcaa aagctttcat tcgtgatttt tgtgcctcta acgaataccc ctctatctgt
    36241 attgacgtag atactcgtgt atagaggtat acttttattt tttcttttga catagtatta
    36301 acctcaatat aatttttcta tatcatatat aattttttta atttaagttt ggactatcat
    36361 ttcaagtata ttataacact tttattagtc cgtctcaatt tgtgtttttg ccatgtcaaa
    36421 actatttttc atatcttgat tttttgctgg cgttggatcg ggtagattat ctaaatctaa
    36481 agcaccagca tattttgcaa tcagatttgc tattaaatca gccaatccat tccagtcatt
    36541 gtccaatata tacctcctct aaagttttat atctaataat tatttgttta attaagtttt
    36601 ttgacattga caagtgcttt ggattagcaa cataggaatc tcacctccgc ctctattccg
    36661 gatgagccgg cttcaacctt agaagtatca ttatcctcat tttcttcata gcggataggg
    36721 tatccctccc tatattcaaa ctcttactta tcgctcactt tctttttgct tagcagaact
    36781 ttttttgccg aattattcag ccgaaagatc ttgacggata ggttattacg ctcaaaaaat
    36841 aattaacgtc ttgtcttggt ctattcaatt gttaaggttc aaaatttatc gagagttatt
    36901 aatcttttta aaatttgacc atcagaaaat atttatcttg atgtaacaaa attctataaa
    36961 ttaccctctt atacttaaca gtgaaaagaa gtctttcttg gtaaccaatt ttgaaataga
    37021 atttgcttat ataaaaaggt tcaattccca ctgcataagt agcagtgaaa attagaccct
    37081 cttggtaact gtcatctaaa agtcttctag catttcttta attttctaat cgcctttaaa
    37141 gtgtcatatt tatatttttt tatctctggc atactttgat acctttttag acttaaagtc
    37201 tttaatagtg cctttccacc tctttttatc tataaagatt ctcctacatc ataattcatt
    37261 tttttattta aacctttctg tcttagtttg tctttatctt cttcatacca ttttaatatt
    37321 gtcacatagt ggttttgata ggtcttacca ctgctttcca tgtatctgga tagtttattt
    37381 atcattatat ctgtgtgtga gtttaatttt tcttttagat ttttatattc ttctttgctt
    37441 aaccttacat ttttgaattc tccataaaaa atgggggtgg actttttatc tatctctccc
    37501 tctctctctt tatctatctc tatatctttc tctatctctt gtcggacatg ggttggactc
    37561 attaaggaca atgtcctctg tttattttgt ctgtatcttc tttttttctc tgcccaggct
    37621 gtttctgatc cgattaagtt tggtatttca gttaggtagt attcatcatt ttctgttaca
    37681 acttctaata agccttgatt gattaaataa tttactgtta ccattacatc atcgtctgtt
    37741 tcatctatgg ttagtgctaa ctcttttata aaatcacttt ctactccgtc ataatagagt
    37801 ttgccctcat cttttaggct tagtagtaga agttttaggt agattatcgt ataggtatct
    37861 cctccagata ttctccttaa cctttttatc cttttgtctg tgaaaaattc ttcttttaat
    37921 tttatccaat agtatctttt gtttgttgcc atatctgctc ctttcttgat tttcgataat
    37981 cgaaattctt gatttccgat tttcggaatt ctggacttct gtttttcgga agtcttgtta
    38041 ttatggttat ttaagggtgt aacttttcgt tactcccttt agatttctct ggtcatatct
    38101 tttttgtttg gttttacttt ttcttttact ttcctttttc ttttgtctta tctttgtttt
    38161 tggataggtc tttgtatttc tttatttgtt tttggatact ttctttttct tttttattta
    38221 gcctataact attagacttt aaagtttcta tttttgtttg taactgacct atggtttcta
    38281 tgttgttttt tcttaaataa ctatatgcac ttgttagctt tttgaagtca tatttttctt
    38341 tattagtttt tgcatatcct tttagatatt tacttttttc tttttgaatt tctgaataag
    38401 ttaatagata atttgttaga ttaaaaagtt tagggttgtc tattacctta tctctttcga
    38461 tatccttaaa tttttcataa gcagtagata agttatctaa taaatttcct atccaaccct
    38521 ttaatgtttt tatctcttct tttattgttt ttacaagttg attatatttt cttatttctc
    38581 tattatagtt tcccttgtca gtttctattc cctttctttc cattgcactt gctgctgatc
    38641 ctaaatggat tgtcggtaga taatctgaat tttgtctttt aaaactccta tggtctactc
    38701 ttttttctgc tcctgctctt tctaaatatt tgttacaaag atctgaaaaa ttttctctcc
    38761 atttttctac attgcctgta tcgttccagg ttgttagttc tacttttctt gtctttggtt
    38821 ttccattttt gtttaatact ttttctcctt tttcatctag gatatattct ttttttgact
    38881 tggctaagaa ctctcctttt tcgtttattg gtcgcattat ggtcattata tgacaatgga
    38941 tatttccatt tttatcttga ctctcatcat gaattgcata atctactatc attccttgtg
    39001 atgttaaatt ttcttttata tatctttcaa ccaggttttt attttcactt aaagataact
    39061 cttttggtag tcctattatg aattgtcttg ctagttgtgc attagaattt ttttctgcca
    39121 tttctacttt attccataag gtagacttat cattaaattc ttttggtata tgatcaggca
    39181 atattatatt ttttactaat attttttctt ttcttgtgta gtcatgggtt actccgtccc
    39241 attcattttt tattttttct ccacttatat atgctgcact tgctactgca cttttgcctt
    39301 ttcctcttga tattatgttt actgaaaaat gaaaactgtc tgccattttt atcacttcct
    39361 ttctttgttg ttttaggtgg aggcttaata gtttttttat atcctctttg tgaatgagcg
    39421 ttttgaaatg atagaattaa aaaagccgac tactgaatta atttttgttg tttcagtatg
    39481 ttggcttaat tgttactttc atttcaaatt ttaaaagtca agggcgagcc ttagcgagtt
    39541 tatttaccct tgacttttaa aaagcgaatg gttgttgctc cctgcaaggg tttgactccg
    39601 caggacgcaa gcacccttta gggtgtataa ttgcgccctt gtaaccaagg gacaattatg
    39661 ttatttcatc tttagatgat ttttctacat tatcatctat tctttcttct aaaatttcca
    39721 ttatgtttaa tcttatttct tcatcattta acgtttttat taacttataa aattcatctt
    39781 ttgttaaatc aatactttct tcaaaaatac tttcaaacac tgcacctttt tctataagtc
    39841 ttttgtttct tgcttttctt tcttgttcat taagtttttt cttcaactgt cttttttgat
    39901 tttgtaattg cttaatgctt tcttctttct tttcaatctg ttcttcaata cttaatcttt
    39961 tacttgccat catgtatcct ttcttaaaat aaaaaacgac tagattttta tttctaatcg
    40021 ttcttgtttt aaatattata atttgctata ttgcatttta attttaagtc ttctatatat
    40081 ctttccatgt aattccaatc tggagtacct ctactgtcta tcggtaattt aattttgata
    40141 tctggcaata ctgtgctaga tatttgatct ttatattcag tattttttaa agcttgccta
    40201 ataattgaag ttaaatagaa tgctacttct ttattcaatt ctttattttt taattttaaa
    40261 caatgaattt tcatatctag gcttgcttta tatttatgat aaaagactgc tcctaaaaat
    40321 gaaacagata taaaattttc aaagactcta taatttttat catctatatc ttcgtagtaa
    40381 cctaagatac cattgtcaat atttgtagca ctaattctag gagtttttcc atcgagtaaa
    40441 tatctttttg gaatagatga gcctgttggt acttaactcg atttcccctt tttttcggta
    40501 ataaatattt ctttttattt tgttgtctga tatttttcct acctgtcctt tgtaggatga
    40561 gtattttcta gattttcttg aataactttt tacttgaagt tttagctttt gaactagtcg
    40621 ttgtactttc tttttgttta ttatcagtcc tgatcttttt aatattgctg ttattctcta
    40681 tatcctattt ttcattcatg atattctttt actaatttta tcttaaattc tgtgctgtat
    40741 ttgccattaa aaaactgacc tcctttagtt agttttttgg cctaactttt gagggtcagt
    40801 tcaaaatttg cgacttttaa atgaattcca atattcaatt attaagagtt aacatggtgc
    40861 ttgccaatag gaatcattag aggcgaattg gaaatagggt cacgtataat ttttgcttca
    40921 agattaaaga tatctttaac tagtttatca tttagtatat cttcaggctt tccctctgca
    40981 acaagtttac cttctttaat tgcaaatagg taatcagcgt atcttgctgt tagatttata
    41041 tcgtgcaaaa tcatgcaaat ggttgtctta tatttttggt ttagatcagt caagaggtct
    41101 aatagttcta tttgatatga gatatccaag taagtagttg gctcatctaa aagtaggata
    41161 cttgtatctt gggctagggc tagagctatc catactcttt gcctttgacc cccagaaagt
    41221 tcttcaacta ggttatttgc tagatcttca acattggcct taaccattga tctgtttatt
    41281 atttcaaggt catcttttcc aagactctta aaaggctttc tgtaggggaa acgaccacgg
    41341 cttacaagat cagctactgt tattgattca gggattattg gagattgagg taatatagct
    41401 atgtgttttg ctaaatcttt ttctttataa gaattaattg atttattatc aagcaatact
    41461 tctccctcta atggctttat aagtcgagac aaggttttaa tgagtgttga tttcccacaa
    41521 ccatttgacc caataataac tgatattttt tcttcaggta tttttatatt tatattttcc
    41581 aagattattt tttcatcata accgcaggta agattatttg accacagacc tttcattata
    41641 tattcctcct gttcattttt attagtaagt atattaagta tggtgaacct aacaagccag
    41701 ttacaacacc tactggatat ctagctggta aaatattttg agagaatatg tctgataaca
    41761 aaactagtaa aattccaacc aatccagcta atattgggct tcttttcttg ccaatattta
    41821 aggctatggg accagctaaa aaagatatac aagctattgg tcctgtaatt gaagtagaaa
    41881 aagcagttaa agatacagcg caaaaaatta aaacaagcct tgaaagctcg ggatttgctc
    41941 caagtccgat tgctatttct tcaccaagtt caataatttc tagtctttta ttaaaaaata
    42001 aaactaatat agtagcaata atacttacta ttagaacaag aggtatgtca tctaactttg
    42061 taaaagataa agagccactg agccatctca taacttcttg taattcatat cttgctactt
    42121 tcaacaataa aaatgaggtg cctgctcttg tgacagcttg aaaaccaata cctaatatta
    42181 tcagtcttgc tgctgaaaaa ccatcttttt tagctagtaa aaataatatt aaagatgatg
    42241 ttagtccaca agttattgaa ataattccag tagttaaact atttgttttt aataccaata
    42301 tgcaaaagac cgctgcaata gatgaagaac ttgtgacacc gattatatca ggacttgcaa
    42361 gaggatttct taacatagtt tgaaagataa atcctgccaa tccaaaagac cagccagcta
    42421 taattcctgc taataatttt ggtaatctaa tttccataat cgaaaaacta gctccaggaa
    42481 cagtttcact atttaagact ttaatcaaag ttgaaaaaga ataactttca tctccgataa
    42541 gtaaaatgaa aaatgataga ctgattatta ttaataaaaa tagtgaggaa aatagtgtta
    42601 ttctattttt tcttttttga atacctataa ttaaattttg cattagttat taacccctct
    42661 atttttcata gttacataaa taagtactgg acccccgatt attgcagtaa ttatccctac
    42721 ttcaatttca cctggtttac ctaacatacg gccgattata tcacatataa gcaagagctc
    42781 tgcacctata aaagatgaag aaatggtcat tgtgcgtata tctttgctta taaataagcc
    42841 acaaaagtga ggaactataa gacctacgaa gccaataggt ccaccaattg cagtaatact
    42901 tgaacataaa agcacacttg caattattgc aagtgatctt atcctattaa cattaactcc
    42961 aagaccaaca gccatttcat cacccatagc taaagcgttt aaatctgatg aaataaatat
    43021 agctatcaag tgacctaaaa ttataaaagg tagtagtgta gatatagaag ataatgtagc
    43081 tgctccaagg ctacctattt gccaaaatct aaatttgtct aagacgttat tattcggtaa
    43141 aattaaaaaa cttacaaaac tgcttaaagc catactaaca caagttcctg ataaggcaag
    43201 ttttataggg gtaaggcctg cttttccgct tacagcaatc gcgtatacaa aaattgcact
    43261 tactaagcca ccaatgattg caaaacttat atggcttatg cttgatgaaa ttcctaaaaa
    43321 agaaagacca attactacac taagacttgc tcctgtgttt ataccgagta tacctggatc
    43381 agctattggg tttctagtaa ctgattgcat caatacaccg cttatggcaa gactagaacc
    43441 tgctaaaatt gcaaaaatag ttctaggtat tcttttatat ataattgatt taataaaatc
    43501 atcatttgta ttacccattc caaaagctgc taaaaaatct ctgatattaa tttcttttgt
    43561 tccaagcttt aatgacaaaa atattgtaat aagaagacct aggcagatta caaaaattat
    43621 gcctaggttt atttgttttt tatttcgcat ttttgcatgc atttcctaaa agatttagat
    43681 attcttcaat agtatagttt attgaaagtg gtgttggagt gcatgaggct gctaacggtg
    43741 tattatctgg aattacagca acggcaccat ttttaattgc atttatttta cctaaaagag
    43801 gatctttttg taaagcttca agagttttat catcaccata agttatgatt acatcagcat
    43861 catttatctt atttgcttct tctgcagaaa tttcctttgc aaaactatct tcactctcaa
    43921 attcttttaa tgattcaggg aaaactagac ctaaatctgt taaataattt gctcttggat
    43981 ctttgctagt ataaatccag aattttgatg tatctgcagc attaatcata gtaaataata
    44041 ctttttttcc tttgattttt cctttgattt ctggatgttt ttctaattct ttggatatac
    44101 gagcttcagt atttttgatt aactcatcac cttctttttc catacctaag gcttttgaat
    44161 caattttaat catatctctc cataaagttt gccaaggttt agatttgtat gctgctacag
    44221 gagcaatttt tgatagagtg tcataatctt ctttagttat accagaataa cctgctaaga
    44281 taacatctgg tttagaattt gatattgctt caaagttaag tccatccaaa tcgtcaaata
    44341 ggttagcttt accatttagt tctttgattt tttcttctgt ccatggtaaa actcctttat
    44401 cagcacttac accgtaattt gcttttgaaa atccaacagg aactattcct aaagctaatg
    44461 ctacatcatg atttccccaa gcaatagttg caactctttc aggtttttta tctaatatag
    44521 tttgaccgaa agcatgatct aaaactattt tatcaggcgc atgctcttta gaagtatttt
    44581 cttcattttt aacagaatta gaagaacaag cgctaaaaac tatacacata gctaaaatag
    44641 ctattagaaa aaatttgttt ttcataaaaa ctccttaaac atatttcaag tctattgtat
    44701 cgataataat tatcattgtc aatagataca gttacaaatt taataatata attttttcaa
    44761 aaaaggatct agtttttatt tttagttaaa ttatgtctat atttttcatt aactcatcaa
    44821 taaaaatttg tttgctaata tctctttctt ctgattttgt ttcaaggatt attgctacat
    44881 cattcatatt tttaggtaaa taccaaccat ctggcttatc tgaatatccc ttgaagccta
    44941 attgattaaa agtagttatt tgaccagtac cttgattgat gttttcttca acttcattaa
    45001 agcctatact tctcttgcat aatccctaac ttgatcttct gtccttaaag tcattttcta
    45061 ttcctcgtca ctaaaattat cttcaaaact aataatatca ttaggagtgc aagataaagc
    45121 cttacatatt ctttctaaat tcttaaatgt aattggttta tcctttccca tttgtgccat
    45181 aacatttgtt gtaagtcctg ccatagctat tacatctgtt ttctttagtc ctttttttgc
    45241 taactgtatc cataatggtt tatagttaag tgccataata tccctctttt tttcttcatt
    45301 agatttattt aattatagca taaatattga tttcattcaa tcttacattg atttagtgat
    45361 ttgttttaga gaatttgttg tgttattccg tccttatttt gccataaatt gttttaagtg
    45421 ggacctctta tccttaccat ttttacctcc taattttgag tataaaaaag acgatagagt
    45481 ttttaatttc tatcgtctga gatttacata ttaaattttc atcacaaaat aagactcttt
    45541 aaagaatctt taaattcatt ggtatgctaa ttacaatatc cattattaaa atggatacta
    45601 taagcagcac accaactatt tattttttga gttttaaact ttggtagaag tcttgaactc
    45661 cttatattta cataactatt tgcctctata actattatga cacgaaacca acaagcaagt
    45721 tcaagcacct ccatatcttt attcaaatga ggactaagat attcacaaac tttatcataa
    45781 acctctttat cttttttcat aaaaggggca tacaacttag caaatttatc ctaaaatttt
    45841 ttgttgcctt tatcaatcat ttcaacactc ctttaaatat aaaaatgatc ctatcaatct
    45901 ttatattgag cctattttct aattgatacc ttgcaagaaa ggaataatag ctgttcctat
    45961 accaagtagg aatgtaataa atgcagaaag tcatatactg tcattctttt ctattaaatc
    46021 attttgaagt gtctcaaagc atccatgatg gcttcttctt tttcaggtgt acactgtgga
    46081 ataatttgtt tatccttttt agacttgttg taatgttctc gtaattctat tccacatttc
    46141 ttttttatct gtgcaatata taatgtcgaa acttttaatt caaatttatt ccaaacatat
    46201 tctttgattt gagcatatgt tgctttgctc tccgcacttg tcaaattcat ctcatccagc
    46261 tcaatttcaa cacttatgtg cttatcgaca tcgagtttgg acaaaagtgc taccgtctcg
    46321 acgtgatgcg tttgaggaaa tagatccacc ggctggactt tcttcaattc atatcccaat
    46381 tcttggtaga gtttgatatc acgcgccatg gttgcgacat tgcaggagat ataggcgatg
    46441 cgatcggctc ctgtttgggc gcttgctttg ataaagcttt ctgtcaagcc cttgcgtgga
    46501 ggatcaacca agataacggt tggttgaatc ccatctttaa gccaattctt catagcattt
    46561 tcagctgtgt cacagacata gtgggcgttt gaaatattgt tcagctgagc atttttttta
    46621 ctattctcaa ccgcttctgg aatcagttca acaccgtaga cttctttgac atgcttggcg
    46681 actgataaac caatggttcc aataccagaa taggcatcaa taatcacgtc atcttttttt
    46741 aactctgcaa agtcaatggc tgtttgatag agtttctccg ccatttcagt attgacttgg
    46801 taaaaggctg ggccagcgat ttggaagtca tttcccaaca tctggtccgt aatatagtct
    46861 tgaccataaa gagtgcgcca ctccttacca aaaatcgcat tggtattctg gtcgttgata
    46921 ttttgcatga cagacacaat ctctgggaac tgcttgataa cttgttcaat caattggtca
    46981 acacgaaaaa cttttggacg agttgtcacc aaaacgacca tgatttgtcc tgaatagtga
    47041 ccacgacgca ccacaagatt ccgaatcaat ccagactgtt ccttttcgtc ataaggtttt
    47101 aaatcaaaac gacggagcag gtctcgaaga gctactacga cttggtcaat gacaggatcc
    47161 tggataaaga aatcttcaag gggcatgagg ttgtgcgaat tcttacggaa aaatcctgtt
    47221 tccaagacac cattcactcg acgaacgggc acctgcgcct tattgcgata cttgactgga
    47281 tgttccatac caagcgtttc agcaacttct acatctgcaa ttccagcaat cttgtagaga
    47341 ctgtccttga cttgcttggt tttaaacttg agctgttctg gataagaaag gtgtcctaaa
    47401 tccgcgattc ctgaacgcag gtaagccaaa tctagatctt gattacggtg tggtgactgg
    47461 acaaggtatt tttcaacttt tccaaagcca atctttttat tgaccttgag gacacgcatg
    47521 agaatttttt cactcggtaa agcattctct acaaaaaaga ccaaaccatc taccttggca
    47581 actcctgccc cttcatgggt caagtcaaca atttcaactt ctacaatatc atttttcttt
    47641 aacattcttt tctctttcta ttggccgaca aaaaagacgg caacgttacg gttaccatcc
    47701 attataccat gaaatttctt aagaaccaaa actcttgaag aagttgacaa gggcttgcca
    47761 gagggagctt aagaagttac caccgtcctc tagcgcctta tccgcatcaa agttaaggtt
    47821 gatattttta aaactgtcgc cagcttgtga tacgatgctt tgtttaaggt catttagggt
    47881 tttagtgaaa tctgcattgc tgaggatatc actctttgag agattcaagg caaaattgat
    47941 gatgatattg atctggtttc ctgttatgac ctgatcaagt ttgtaatttt ttaaggtatc
    48001 ttcaacaatc ttgcgtacat cttcttctgt cagatttccc ttgctttctt tagctttggc
    48061 gagtcctgac ttgatatcag ctagggcaac gtttaattta ttagcatcat agcctgattt
    48121 gtccttgttt tcagcattga tatctgacaa agcctttagc tcttcttgag ccaaatcttt
    48181 attggcttgc ggcaccttgg ctccattagc ttctagcgaa tagtagatcc cagccaaagc
    48241 actctcacct gtaactggaa taggggctgc tacagtgatt ttggcatgtt ccatacccag
    48301 cgttactgct gcgtttcggt acatatcctg agtcacctta gtgatatttt ctggtgtttc
    48361 aatcttgacc tcaagtggcg atttgtcacc tagcttttga atcttggctg atgaatacaa
    48421 ctgtaagcta gagtcattgg ccacattcat gattttagaa taaacatcag gtgtcatggt
    48481 cttgagttct ttggtatctg ttgaggcatt gtagcccagt tttttaagag tttgattttt
    48541 ttggtcttca gatagggagg aacctaggac atattcaggt tggacatagg tttcatcgat
    48601 aactttttga acatctgttg ctgcatgggc gctattcata gctgttactg cccacaagac
    48661 cgcagcactg gtcagaaaga gtttctttct catagggaat ttcctccttt acttttctag
    48721 agtaatatat ctatcttaaa gaaaacttat aacaaaaaca cctggtctag ccagatgttg
    48781 aaaagagagt gaaacatttg atgatgtaaa ggttaagtcg tacctgtcta gaataataat
    48841 agtttcctcc atttacatag agttcagcac cgtgaaaaat ggaaatgggg tgaatataac
    48901 tataagtctt tccagtcgta ttaccaagca agggggcaac agtctcacga gagtactgtt
    48961 tggctagagc caaggtattt tccttgccat tttgggcgat aaaatcgata taggcaggtc
    49021 caaaattata ggcttgaaca gctgtccaga tatctacacc cttcttctgc gccagataga
    49081 gattgcctgt cagagtttga atgccttgcc gaatgctaga ggcattatca ttgatggtat
    49141 tggtggaacc acttgcagac tcactagact gcataacatc gccttctttt ccttttgttt
    49201 cagtataaat catagcaagc acaagctctt cgtttgctgg ggtgtctttt tcactcaata
    49261 tttctcgcac catgggttga taggtcatga cttgtttgac atcttgatga acgcggtaag
    49321 ctttatatcc agcaaaaagg aagactgcta gtacaagcac tcttcgaatt cgtttaaaca
    49381 ttatttactt tggatatcct cgatattttt gattaagata gagtaggttc cattttcgtt
    49441 ttggataaac tcaacagact cggcgtcttg atagacgtta ttgggaacga tgagctcaat
    49501 tccatttgat aaggagagtt tttggttttc aaatttcttt aattggcgac tggcatcaat
    49561 ttcatcaaat tgaacaggtt ctggtacggc ttctttgact tggtcaataa agctcaaacg
    49621 agccgtcaga ttgttgtcaa aaaggtcatt agccaatttc tcaggtgaca attcattgct
    49681 ttcttctagg ttgttgaaaa tagctgattt gaccttggat tgaaattgaa aatcatctgt
    49741 gttaaaagat tcagcaattc tctgggctgt tttttccagt tccttgatag attttttagg
    49801 agaaatctta ggagcgacag caagaagatt atctgaaaaa tagttcaaaa aagtcccgtt
    49861 gtacttgatt cgtttttcaa tcaggtgata cttgctactc tgaagattga ccaccaaggc
    49921 ctcatcagct cctgttccaa atccaggcag gttattctga gttagcttga ttggattatc
    49981 aacttctcct ccgaggtggg tcaaggtctc ccgcagggca attcgcaaga aagcgaaatg
    50041 ttctacacct tctttagaaa attgaacaaa aatcaagtca ttggtcttga gattttcaga
    50101 aatgctaaac tcctctttcc agagattagc cagcgttact gatgtctcca acaaatcgtc
    50161 tgtaatatga ttgaagaagg gattttcttc ttcgaaaatc ccagtcttgg cttcatctga
    50221 atacacatgt tcaatttttt tacgtaggta ttcttcgatt tttggagtaa tattgagaaa
    50281 cttatctgct aagaacagct cggtatcatc cggactgaac tggtgaataa tggctttctt
    50341 aatataaatg tccataaaag ttttattcct cgtataatgg gaaggcatct gtcaattctt
    50401 tgactgcact tctcacttct tctaatacag cctcattttc tgaattctta agggttttaa
    50461 tgatgagttc agccactttg cgactttctt cttcaccaaa tccacgtgca gtaatagctg
    50521 ctgctccgat acgaatccca cttgtcttga atggtgacaa gctttcgtaa gggattgagt
    50581 ttttatttaa ggtaatattg acttcatcca acaagttttg agcaactttg ccgttttcta
    50641 caactttagt cacatcaaca aggaagagat ggttttcagt tccacctgaa ataatacgga
    50701 aatcagggtc ttgcaagaag acatctgcca tagccttgct gttcttaatt acattggcag
    50761 catattcctt gaaggctgga tccaaaactt ctttgaagga aactgcctta gccgccacaa
    50821 catgctctaa aggaccgccc tgaatacctg ggaaaatagc tgaattgatt tttttagcaa
    50881 gttcttcgtc attggtcaaa atcaaaccac cacgaggtcc acgaagggtt ttgtgggtcg
    50941 ttgttgttgt gatatgagcg tatggaactg ggcttggatg aaggccagcc gcaaccaagc
    51001 cagcgatatg ggccatgtcc accatgagct tcgcaccgac agcatctgcg atttcacgga
    51061 attttgaaaa atcgataatt tgagaatagg ctgaagcacc agctacaatc agttttggtt
    51121 ttacttcttg ggcttgtttc aagatagcat caaagtctaa gagttccgtt ttaggatcaa
    51181 cactataaga aacaaagttg taggtttgac cagagaagct aacaggagcc ccatgagtca
    51241 aatgaccacc tgatgccaaa tccattccca taaccgtatc acctggctca atcaaggaca
    51301 tgtaagccgc acagttagct tggcttcctg aatgtggttg aacattggca aatttagcac
    51361 cgaaaatttc ttttgcgcgt tcaatagcaa gagtctctac aacgtctact acatcagttc
    51421 caccataata acggcgtcct gggtaaccct cggcatattt atttgtcaag atagaccctt
    51481 gagctgccat aacagccttg gaaactacgt tttccgaagc aattaactcg atattatttt
    51541 gttggcgttc ttcttctttg gcaatagcat tccagagatc agcatcatat gctttaaaat
    51601 catctttgtc aaaaatcata ggtcttctcc tttattgtgt gactagtcca ttagtttgat
    51661 tttacaataa gaaaatcaaa ctaacagatg cgaataaacc gtttctgcat tttatcacaa
    51721 gtatagccaa ctttttcata aaatgcatga gcacccagac gatgattggc agaatttaag
    51781 cggataaacc cataaccaca tctttttgct tcttcttcca acccttgtag taaactttta
    51841 ccaatacctt gaccttgcgc ttgaggtgaa actgctaaag ctaagatatt aaatcctgct
    51901 ttggaataga gtgattcgta aacttcagcg tggacatatc caagtaagac atgattagct
    51961 gcatcctcat agccaagtag gaaatgatgg gaatcctgag acagtctagc tagttggcta
    52021 gccgtttcct ctggactaaa agtataaccc aaagcctctt ggttgatgtc acatatcgct
    52081 ttcacatctg tttcttgcaa atctcttagc atttcaagcc tcctcaaaag aaatctctga
    52141 caaccgagca agaatatctt ctcgtttaat tgcgccttgg cgtaagattt tcaccttgtc
    52201 tccagacaaa tccacaatag ttgaatcctg tccagttaga aaagcatcgt cttccagacc
    52261 cagaacctct tggtcaaaat ccttcagaat ttgttcaaag gttacaccac ttgcctgacc
    52321 tgagatattg gcagacggcc caatcaaggg acctgtctct cgaattaaat ccagtgtgat
    52381 agggtgactg ggcatccgaa atccaatagt tgcaaggtca gaatttaccc aatagggaac
    52441 tcggtcattg gcttcgagaa taatggtcaa gggacctggc aaaaaggtct ctacaagttt
    52501 ttgtagataa gctggctgat tctttgaaaa gtgcaagatg tcctcgaaag aggcgatatt
    52561 gagattgagt gccttatctc taggacgacg tttgagttgg taaacatggt caactgcttt
    52621 ttcatctaag gccttggaaa aaagaccata aacagtctct gtaggtagaa cgacagctcc
    52681 acccttttcc aactcttgtc taatcctgtc catcatcaac cacaaccatc ctattttgac
    52741 caaattggtc tttgagtgtt cgaactcttt tttcaggaag atgttttcta aaaagttcgg
    52801 gaacactttg accttgcttg tatccaattt caaggtaaat cttaccacca tccttgagat
    52861 agtcttttgc atcttccgca attctacagt aaatagctag gccatcctcg tctgcaaaga
    52921 gagctagatg aggctccgaa tgcaaaacat tcaagcctac ctctgactca tcttcacgag
    52981 agatataggg tggattggat acaattatat catatttttc agaaatttct gcaaaacaat
    53041 cagatttttt aaaaaatata ttaagatttt gatcgctagc attctctgat gcaagctcta
    53101 aggcctcttg agaaacatct gctgctgtca ctgaccaatc tggtctattt tttgctagag
    53161 cgagagcaat agctccacta cctgttccaa tatccagaac tgagagattc gtctcaagat
    53221 tttcagttag aataagctcc actaactcct ctgtttctgg acgaggaatc aaaacccgtt
    53281 catccacctt taaatgcatt ccataaaaat ctgcctgtcc aatgatgtac tgagctggct
    53341 tgtgagctgc tagttgctgg taaatatctt ctacaaattg tttttcttcc tctgttgtca
    53401 cctcctgctg gagggcaaaa ataaagtctg taaaagatag atttttcaga ctacgataga
    53461 caaaagagag gctttccgct tcctctcctt gtcttatcaa ctcttcttca aaatttgaaa
    53521 ataattgagc taatttcatt atttgtttaa ttcttctagt ttttgtgttt ggtcataaag
    53581 caccaaggca tccacaactt cgtccaattt accagacaaa atcgtatcta gtttttggag
    53641 ggtcaagccg atacggtggt ctgtgacacg gttttgtggg aagttataag ttcggatccg
    53701 ttctgaacgg tcaccagtac cgattgtcga cttacgctca gcgtcttgtt catcctgagc
    53761 aatctgagca aagtggtcag cgacgcgtgc acggataatc ttcatagcct tctcgcggtt
    53821 cttctgctgg gtacgttctt cctgcatctc aaccttgata ttggttggca agtgaacgat
    53881 acgaacggca gtcgcaacct tattgacgtt ctgtccacca gcaccagagg cgtgatagat
    53941 gtcgacacga aggtcttttg gatcaatgtc gtattcaacc tcttcaactt ctggcataac
    54001 aagaactgtc gctgtcgaag tatgaacacg gccttggctt tctgtcacag gaacacgttg
    54061 cacacggtgg gcacctgatt catacttaag cttagagtat acagactgac ctgaaaccat
    54121 agcaaccact tctttaaaac caccgacacc attcatagag gcttccatga cttcaaagcg
    54181 ccaaccttgg gcttccgcat acttttggta catagttagc aaatctccag cgaaaagtgc
    54241 cgcttcgtct ccaccagctg ctccacggat ttcaaggatg atattcttgt catcgtttgg
    54301 atcctttgga aggagcaaaa ttttcagttt ttcttcatat tcttcttttt cagccttggc
    54361 atctttgagt tcttgcttgg ccaattcttc caagtccgca tctccgcctg attccttaat
    54421 catctcttcg gcatcgacga tattttgaag gacttgttta tactcacggt aggctattac
    54481 ggtgtcacga ttggaagctt cttcttttga aagctccata aaacgcttgg tgtctgaaac
    54541 gacatcaggg tcactcagca attctcctag ttcttcataa cggtcttcta cagcttgtag
    54601 ttgatcatag atgttcattt ttcttcattc tccttattga tttcaggggc aaaataatgt
    54661 ttacggcaaa ccgagatata ggtttcatta ccaccaatct ggatctgttc tccatcgtaa
    54721 acgggcagtc catcctgtgt tcgcaacacc atggtcgcct ttttcttgca atactgacag
    54781 atggtcttga tttcgtcaat cttgtccgct aaaagcaaga gatatttgga accttcgaac
    54841 aattcattgc gaaagtcatt tttcaagcca aaagccatga cgggtatgtc taactcgtcc
    54901 acaacacgag ctaggtcata aacatggtgg cgtttgagaa actgggcttc atcgaccaaa
    54961 acacagtaag gtttttctgg taggtctcgg atatagccaa agatatccgt tgtttcctca
    55021 atcgcaaggg cagggcgttt catgccaatt cgactcgaca catagccaac accgtcacgc
    55081 gtatccagag ccgaggtcat aatgacaaca ccttttcctt gctcctcgta gttataggcc
    55141 actttgagaa tctcaatcgt tttaccagag ttcatggtcc cataacgata gtacaactgt
    55201 gccatgtttc ttgcttcacg tccatttcta aatttttgct acattctagt atatcataat
    55261 tttcttaagc tttaaacggc aaaatgtggt aaaatagaag aaatcaaaaa ctagtggagg
    55321 aagctattat gccatttgta cgcatcgatt tatttgaagg acgcacgctc gagcaaaaga
    55381 aagctcttgc taaggaagta acggaagcgg ttgttcgcaa cactggagca cctcaatctg
    55441 ctgtccatgt catcatcaac gacatgccag aaggaactta cttcccacaa ggggaaatgc
    55501 gtaccaaata agctagctta agcagaattg cttaggcttt ttcaatctcc aagtagcatt
    55561 cattgaagaa atatcctaaa tttgttacaa tttgaaaaga aacttggaga atttccaaga
    55621 aaagagcaat taattaaagg aaacattatg attacacgtg aatttgatac catcgctgct
    55681 atatctactc cactaggtga aggggctatt ggtattgtcc gcctgagcgg aacagacagt
    55741 tttgctattg cgcaaaagat ttttaaagga aaagacttga acaaggttgc cagccacact
    55801 ctcaactacg gtcacattat cgatcctctg actggtaaag tcatggacga ggttatggtt
    55861 ggggctatga agtctccaaa gaccttcact cgtgaggata ttatcgagat taacacccac
    55921 ggtgggattg cggtgaccaa tgagattctc cagctagcta tccgtgaggg agctcggttg
    55981 gcagaacctg gtgaatttac caaacgtgcc tttttaaacg gtcgcgtaga tttgacacag
    56041 gccgaggcgg tgatggatat catccgcgcc aagacagaca aggccatgaa cattgcagtt
    56101 aagcaattag acggctccct ttctgacctc attaacaata cccgtcaaga aatcctcaat
    56161 acacttgccc aagttgaggt caatatcgat tatcctgaat atgatgatgt tgaggaagct
    56221 actactgccg ttgtccgtga gaagactatg gagtttgagc aattgctaac caagctcctt
    56281 aggacagccc gtcgtggtaa aatccttcgt gaaggaattt caacggctat cattggacgt
    56341 cccaacgttg ggaaatcaag ccttctcaac aacctcttgc gtgaggacaa ggctatcgta
    56401 acagatatcg ctgggacaac acgagatgtc atcgaagagt acgtcaacat caatggtgta
    56461 cctctcaaat tgattgatac agccggtatt cgtgaaacag atgacatagt ggaacaaatc
    56521 ggtgttgagc gttcgaaaaa agccctcaag gaagccgact tggttctact agtgctaaat
    56581 gccagtgaac cactgactgc gcaagacaga caacttcttg aaattagcca agataccaat
    56641 cgcattattc tacttaataa aaccgacctg ccagaaacga ttgaaacttc gaaactacct
    56701 gaagacgtta tccgtatttc agtccttaaa aaccaaaaca tcgacaagat tgaagagcga
    56761 atcaacaacc tcttctttga aaatgctggc ttggtcgagc aagatgctac ttacttgtca
    56821 aacgcccgtc acatttccct gattgaaaaa gcagttgaaa gcctacaagc cgttaatcaa
    56881 ggtcttgagc tggggatgcc agttgatttg cttcaagttg acttgactcg tacttgggaa
    56941 atcctcggag aaatcactgg ggatgctgct ccagatgaac tcatcaccca actctttagc
    57001 caattctgtt taggaaaata agaaaaatcc atgatccttc attcggtcat ggattttatt
    57061 gtctttatta gtaatctggt cttaagaccc ctgttacagt tgccttagtt gcttcgtagt
    57121 cgccatctac gacaaccttg ataatgcgtt tggcatcttc ttctggtgct ggaacaagag
    57181 gtagacgagt gggtccagct tcaaatccca tatagttaag aactgcctta actggagcag
    57241 gacttggata agagaagaga gcattaacct taggaatgaa tttacgctga attgctgcgg
    57301 ctttcttcat atcgctttct gcaatggcag taaacatctc gtgcatttca tccccatttg
    57361 tatgagaggc aacagaaata accccatccg ccccaaggtt catggcatgg aaagcatctc
    57421 catcctcacc tgtataaatc aagaactctt caggcttgtg ctcaatcaag taagccatat
    57481 tagccaagct agtacattct ttgacaccga taatatttgg atggtcagcc aaacgaagca
    57541 tggtttctgg agtcaattcg acaactacac gccctggaat gttatagata ataattggta
    57601 ggtcagaagc atctgcaata gccttaaagt gctgatacat cccttcttga gaaggtttgt
    57661 tgtagtaagg aacaatagca agcccagctg cgaaaccacc aaattccgct acttctttga
    57721 caaactcaat agagtcacgc gtatcattag tacctacacc cgcaatcaaa ggaacgcgtc
    57781 cattgacaac cttttgtaca gccgcaaaca actccaactc ctcatcgtgg gtcaaagttg
    57841 gactctcagc agtcgttcct gcgagaagaa ttccatccgt atgatgggcc aataaatgct
    57901 caatcaaggc tggaatagca tcaaagttaa tggaaccatc ctcatggaag ggggtaataa
    57961 aggctgtaat gattttacat tcttttaaat cttgataaga cacgaaaaca cctctctatt
    58021 tcaaagaagg agttcatctg aactcctaaa cgatatgact attttaattc aaatttcaat
    58081 tcggctgttg gacgaaccaa tccacgttca tgaagagttt cagcaatctg aactgagttc
    58141 caagcagcac ctttgagaag gttatctgaa acaacccaca tgtgaattcc tttttctgca
    58201 tccatgtctt tacggatacg accaacaaag gtatcacgcg aaccaactgc attgatagct
    58261 tgaggataga tttgatgagc tacatcatct tcaagaacag cacctgggaa ggctgcgata
    58321 gctgctttta cttcttcgat tggagccact tcttttgttt cgatataaac agactcagag
    58381 tgagctgaca agactggaat acgcacacat gttgcagata ctgcaatgct atcatcttcc
    58441 ataattttct tagtttcctt ggtcatcttc atctcttcgt acgtgtaatc attatcagtg
    58501 aaaacatcaa tttgtggaag agcgttaaag gcgataggat aatgtttctt gtcaccacct
    58561 gaaggcaaga tttccgcatg caaatcacgt ggtttcacac catcattcaa gacttcacga
    58621 agttcacgtt gtgtctcaag aattgctccc ataccagcac ctgaaacggc ttgataagtt
    58681 gaaacaatga tacggtccaa gccccatttt tggcgaaccg gctcaagagc caccatcatt
    58741 tggattgttg aacaattagg gcaggcaatg attccgttgt gagcatcaag tgcatgagca
    58801 ttgacctctg gaacaaccaa aggaacatct ggattttgac ggaaataaga tgtattatct
    58861 actactacca cgccagcttt tactgcgtat ggtgcatact tagctgatgt agaactacct
    58921 gctgaaaaga gagcaatatc aactccttca aaagctgttt cagtcgtttc ttcaattgta
    58981 atatcttgat ctttaaattt caatgactta cctgctgaac gtgcagaagc aaggtaacgg
    59041 attttatcga ttggaagtgt tgattcttcc aacattttta tcatctgagc accgacagca
    59101 cctgtcgcgc cgactacagc aactgtatat cccataaata acctctttcg gaattttcta
    59161 aaaatttcta taatagaagt attatactac tttttccatg aattgcaaag ctttttcatt
    59221 attttttgga aaataaaaat cccagtcgct agactaggga ctaagaggca tcttcatgtg
    59281 atgagcaggt tcacacaact catcaaggtc cgctcctgcg ttatgacctc cttatgctca
    59341 atagtagtcc gaagactacc tatcgactca tcgcatattc tatattacta gagatacttg
    59401 attttgtcaa taagaaattt tttcgatcga gtataacaaa aaactcttgt attcaagagt
    59461 ttccctatac atatcatgct aattgccggg attgaaccgg cgacctcatc cttaccatgg
    59521 atgcgctctg ccaactgagc taaatcagct tacttaagaa gtatactata atcagaaaaa
    59581 cttgtcaagt ttccttagaa attttccata ggaaaaagcc aggtaagaac tacctagctt
    59641 atcttcttct atttacttaa atcaattcga cgaccaattt taccaataat aatcgctcca
    59701 ataatcaatg aagcaaattc accgattcct gttgtaaacc aagtaaggaa gaatggtaat
    59761 tctgctacaa tatttaactc tgcagcgata gtaaacatgg aaattgaaaa gaggattgaa
    59821 aagaagaaat gatcttttcg aatcaatccg ttaaagaggt aatccttgct atattttgca
    59881 aaaagccaaa cacctaaact gaggaatact aaggttgaac caccaccaac aaagacatct
    59941 agcagtccga agctaaagaa attagcaatc atacaaccga tggtaactcc gatgatgtac
    60001 ttaggattgt aaaaagccat aaagttcatc atttctgaaa tacgaaactg ataagcacca
    60061 tagctgatgg catttagggg cggtgtgaca gtcaaaacga cgtagatagc agcgacgatt
    60121 gcaatatctg caacatcacg aatagttaat tttttcatct tttctccttt ggcggttatc
    60181 cgcgtgtaat atgcttggtg aaagaagcta agcaccaagg gttgattcat tcaaccttac
    60241 tagtatagca caatagcctg ctttatgcta tacttaaagc atgaaaaaac ctattcaaaa
    60301 attttttaac aatgaaatct tagcctatct cttttttggc cttgcgacaa ctctagtttc
    60361 gattctctca cgactagtca tttatcaact aagtcatcag gaactccttg ctacggcctt
    60421 ggcaaatatt atcggtatct tatttgcctt tatcacaaat gatacgattg tatttaagca
    60481 aaaaaagaaa aatagactta tccgtttagt gaaattttct cttgctcgcc tttctacttt
    60541 tctgttagac ttgtttttaa cttttctctt tgtaacccaa tttcctcaca tcatagggca
    60601 attcgtaact gaaaacattg ataagataaa tgctattgaa acaataattg cacaaatatt
    60661 cattattatc atcaattata tcttgagcaa ggtctatatt tttagaaaat aatgctccat
    60721 ttatgagcct tttaattgcc ttctataatg atttaggata caatgaaaca cgaaacattg
    60781 aaaggaaaac agtatgttaa aaaatctaaa atcgttcttg cttcgaggaa atgttattga
    60841 ccttgctgtc ggtgttgtca ttgcctctgc ttttggtgct atcgttactt cacttgtaaa
    60901 cgacattatc actcctctta ttttaaatcc cgctttgaaa gctgctaaag tcgaacgtat
    60961 cgctcaactt tcttggcatg gagtcggcta tggtaacttt ttaagtgcta ttatcaattt
    61021 tatctttgta ggtaccgccc tcttctttat tatcaagggc attgaaaaag cacagaaact
    61081 gactggcata aagaaagaaa aaactgccga aaaaaaacca accgaattgg aagtccttca
    61141 agaaataaaa gctctccttg agaaaaaata atcgattaaa aggatctagc gcaaagctaa
    61201 atcctttttt ctttactctt tgggtaactt gcctgctttt tcaagcattt ttttgataag
    61261 ataaggcatc ttaatattct cccgcccttt tttctcaatc agttttttca caaattctgg
    61321 catttgtaaa tcttcagatt cagctaaaat gtttttcgtc tcgtctgaag gaactaactc
    61381 atcaaaggtc tcttcttctg ggagaaattc cttaaactct tgattttcat tgactctaac
    61441 tgtattgacc aaagcatcaa tcaaacgaga atctgtattt ggcattggtg gacgatggta
    61501 gtttacccca aattcctgac ataaatcata acattccaca tcattgtcaa acaagacctc
    61561 aatatgctca ctgatgaaac taataggtac aaaaatataa tggtctggat gttctgtctg
    61621 ttctctgaga tactccaaaa catctggttt aatccatgga ataccaatat cactctcact
    61681 ctgccaagtg ttggtatatt gttctgaact caagcccagt ttttcagcga ctagcttgct
    61741 attttcgaaa atttggtcta tataaggatc tccaaagtcc aaggcaaaaa taggcacact
    61801 atgggctgaa aagatgactt taaagctgtc ttgctttact tcttctttta aaatcttagc
    61861 aatttcatct gcccaatagt ttaagagcgc ttcttcctga taccagtcct taatgaccaa
    61921 aaattgaatt tgtttgcttt ctaaaaattt ttcatagccc atgacagagt agaaagaata
    61981 atggggctcc aaaatcaagc aaatacactg ttcaattccg tctgcttcca tttgaccgat
    62041 cacatctgga ataaagggac tggaaaactt attagcaaag tagacactgt attcattccc
    62101 cagcctagct tctaccaagg caacctcttg acgggtaatt ttttgcagag gcgtgcctcc
    62161 aattcgtaca taattatcat agagagtctg aatctcgtgg tcttggggtc tcatcccacg
    62221 acgaatattt gtgaaaaaat cagctacacc ttcaaaggta atctcttctg gtgaaccgaa
    62281 ggtcatcatt aaaattgctt ttttcatgac tgcttccttg tgatgttttt atcaagttta
    62341 ttttatcatt aattcatcga taagtaaacg ctagcatagg gacattctca atcttctgtc
    62401 ttttgttttt ctcttctttc tatgatacaa tggaaaaaat aaattcaaaa ggagtttttt
    62461 atgacttatc caaatctctt ggaccgcttc ttaacctacg ttaaggtcaa cacgcgctct
    62521 gatgaacact ctactactac tccaagtaca cagagtcagg ttgacttcgc aacaaatgtc
    62581 ctaattcctg aaatgaaacg tgttggactg caaaatgttt actatctacc gaatggtttt
    62641 gctattggaa ccttgccagc caacgatccg tctttaacac gtaagattgg ttttatatcg
    62701 cacatggata ctgctgattt taatgctgaa ggagtcaatc cacaggtaat tgaaaactac
    62761 gatggtggtg tgattgaact agggaattct ggtttcaaac tcgatccagc tgacttcaag
    62821 agtcttgaaa aatatccagg acaaacgctc atcacaacag atggaacaag cttgctaggc
    62881 gctgatgaca aatcaggaat tgctgaaatt atgacagcca ttgaatatct aactgctcat
    62941 cctgaaatta agcactgtga gattcgtgtt ggttttggtc cagatgaaga aatcggtgtt
    63001 ggtgccaata aatttgatgc agaagatttt gatgtggatt ttgcctacac tgttgatggt
    63061 ggtccactag gtgaacttca gtacgagact ttctcagccg ctggtgctga attgcatttc
    63121 caaggccgta atgtccaccc tggtactgcc aaagggcaga tggtcaatgc ccttcagcta
    63181 gcaattgatt ttcataatca acttccagaa aatgaccgac ctgagttaac tgaaggttac
    63241 caaggttttt accatctaat ggatgtgaca ggtagtgttg aggaggcgcg tgcaagctac
    63301 atcattcgtg attttgaaaa agatgccttt gaagcgcgta aagcatccat gcaatctatc
    63361 gctgataaga tgaatgaaga acttgggagc gaccgtgtca ctctcaactt gacagaccag
    63421 tactacaata tgaaagaagt cattgaaaaa gatatgactc caattaccat tgctaaagcc
    63481 gttatggaag atctaggtat cacgcctatt atcgaaccaa tccggggtgg aacagacggc
    63541 tctaagattt cctttatggg aatcccaact ccgaatatct ttgcaggtgg cgaaaatatg
    63601 cacggacgtt ttgaatacgt tagccttcag actatggaac gtgcagttga taccatcatt
    63661 ggcatcgtag cttataaagg ctaaaaagac gaggtagctc agctacttcg cctttctttt
    63721 tattctactg gtttttcttg atttccagta gttgtagaag attctgttgt tttattttct
    63781 gaagttgatt cagcaggttt agaatctctt gtattgcttg gtttgttttc gtcgctagca
    63841 gtttcaatgt tagattctgc agttgcgttt ggttggttct cagcactggt gttatcacca
    63901 tttgcttcag catttcttgc tggacttgtt tcttcacttg cgctagcttt tgactggatt
    63961 tgatgattca aaactagaat agcttttgtc gattcaagta aagctgtttt gtctttacta
    64021 ttagcagaaa gttgatctaa taatgcatcc accttatcaa aagtccgcat cagatccatt
    64081 attactttct aaataaaagt gaagcgacat gagaatatcg tagagttttt gatagagtac
    64141 aagtgtctga ggatcttgct cagcattttc cttttcttgt tgaagggcgc tagcgatacg
    64201 agtcaagaca tcttttacct gactgtttac ttcatccaag tctgcatcag ccttgtttgt
    64261 ggcagctttt agattttcta cttcttctgc caaagattgt ctgattcctt cttcatggat
    64321 tcgttccaag agttgatttg ccttgctcaa aagactttct acttcttcct tgctatctgt
    64381 cgcagattat tggttgctat ctaccatgta ctcctaaaac aggagagtta taatccaaga
    64441 ttacaaggcc ttacagaaat aagaaatcca gataagacaa tgttcgtcca agacgctatt
    64501 cgcttcgcac agcagcacgg attcaatatg ctttaatttt aaagtttagg tgtcaagacc
    64561 tctttttagt gtgcccaaaa tttagagaag taatcaatca actaactttt atttttttca
    64621 aactttcagt aaactgacct aaagctaact caatctgtct ttgttcgata ggcttgtctt
    64681 tgtagatgct tctgctatca gctagaagtt gatctacttt tgccaagact gccttctcat
    64741 caaaagttcc aggttgatag ttggattgca gggatggaat cttgtttttc aaagccgctt
    64801 catatccctt agtttgaacc ttgatgtagt gattgtggtc gccacgagga atcacaaaac
    64861 cttctgaatc ttcacttata attcgattgg catcaaaacc atgaccatct tcttcctcat
    64921 ggtggacatg tagtgacgga ttacttaata cagaactaga agaacttcct acctcttccg
    64981 tgttagagtg tgatggggga ttgttaagag atgacttagg aatatagtga tagtgacccc
    65041 atgtcttact atataagcat cacctgtatc tctgacaata tcattagggt taaagacata
    65101 accatcatct gctgcagaaa caccattatt cggtgtcacc gacaaagatt gactgagagc
    65161 tgtagtattc tctgataatt atacttttgc agctgctaat tcacctgccg acaagtcact
    65221 ctcaggaatg aaatgatagt gaccaccatg tggtactata gtagattgaa atagaatatg
    65281 agcaaattga taaggggatt ttaaagtaat ttctaacaat gatttagaaa ctatgatgtg
    65341 ctattctaaa ttcaactcac tatatataac catcatcggt agtataacgt ccctgtaatt
    65401 ttactacaga tacttctgca ctagctcctt tatcgtcttt accatgttct tgtttttggc
    65461 gattgatttc atcttttatt cgtacatttt ctgcatgagc ttgatcttta aggtaaacat
    65521 aatactttcc atctacctta ataatatatc ctcccttaac ctaactgacg atatcttgat
    65581 ctttcggctg atagttgggg gctttcatta atagctcttc actaaagagc gcatccaaag
    65641 gaactttacc attatagcag tgataatgat cgccatgaga agttacataa ccttgatctg
    65701 taatcttaat aacaatttgt tttgcttgaa ttccttcttt ttgactaacc tagtctggag
    65761 tcaaattttc agtcttctta gtgtctttat tactgtttac atatgaaaca cgatttttat
    65821 ctgtattggc ctgttagcta tgttggttca gagcataaac acacagactt aaggaaagga
    65881 taacaacaga tccagctgct atatatttct ttttaaattt cataattacc tcatttctat
    65941 aattatttat atgatgtctt cattattaaa tgattaaata aattaattaa ccaattaatt
    66001 aactagtaaa tattccacct ctttttaagt tgtatgtcaa gaaattttat atattaataa
    66061 taaaatgaaa ttctcccaaa gtcagagttt tatttctaac ttttgagaga acttcatttt
    66121 tgattcagac tttttctact gctattcctt acgctatgag atcagataaa ttctttttta
    66181 tcacttctcc acttggcaat cttaattcaa tcgttccatc catattgaat ataacactat
    66241 ctaaacctaa tccgtaacta gctgtaaatt tttctaattt ttcttgtaca ggatctactg
    66301 ctggagcttc ctctaatgct ggatctaaca tagggtcact ccccacattc ccttctggat
    66361 tcaacattcc attatccgtt gagttttctg gttttacagg tttttcgttt ggtgcctctg
    66421 gtaaagaatc tgctggttta ttttctgttg gttggttctc aactgttcca gtagatactt
    66481 ttccattttc agatggttta ttttcaccat ttccttgagg tgcttctcct gtaaaatctg
    66541 ccatattctt tttaatgact tctcccgatg gtaaatataa ttcaattgtt ccgtccatat
    66601 taaacaagac attttctagc ttcatcccat aactttcagc aaattttgct actttttctt
    66661 gtacaggatc cactgtagga acttcttcta acgttgaatt actagtacta ttcccagttt
    66721 cagaaagttt ttctttttct accttctcac tagtctttgg ttcttctacc ttttcatcaa
    66781 gttttgagtt ttcttgtgct ttattccttt taaattgtgg tagaatactt ggtttatcag
    66841 tttgattttc tttttccaag ataggtactt ccacaatata agtcgattga ttgtccaaat
    66901 aagcatttgc catgaaggtt acaggaattt tatttccggc cgttctggtt gttccttggt
    66961 ttaatttcgg aatcggtaat ttaatttcac caactttata gttattttct aaataagcat
    67021 ttccatgaaa ttcatcaaac actctgacta aagcatcagt tcctttaggc actgcaaatt
    67081 gagggttcac tcttaaataa gtatcccctg catggaaagg atagaaaatc gtttgactgg
    67141 ccattttgta agctaaagag gttggaactg taaatgtacc atcataactt acttctggat
    67201 aatcttttga agcgatagta tacttaaatg tttgtcctgg taaataaggt tgatctaatt
    67261 caaagtttgc aatattccct actccttctc caaatacttt accagatact ttctccaata
    67321 cttttccatc tggtgttatt aattttacta gcatattgat acctaatttt ttctccaatt
    67381 caggcggaaa actaaaagaa acgcgttttt gaccattggc tagagtaaag ttttgattat
    67441 taaacgtact attttttaac aaattaacaa cattcgttaa ttcttctcca gtataaactt
    67501 tattcccttc ttttttagca actccttctt cgggtttaaa cagttcatag ttactgtgag
    67561 aatgaccaat tccaaccggt ttatgttcat caatcggatc tgcatgatgg tgatctccat
    67621 gcggataaat aatcgcattt ttttctttat tcacgacaat actttcacgt ttgacaccat
    67681 attgtttcat aatgccagca attttttctt cgattttttt atctaaatct ttcatttctt
    67741 tggcattact tggataatcc tgttcatgag atgacaaaga atctaatcca ttatgactag
    67801 ttttaacttc ctctaaatgt ttttgcgcag ccttaatttg ctcttctgtc aagtccttct
    67861 tgaagaaata atgattgtgg tctccgtgac tcatgacaaa acctgattca tcttcagcga
    67921 taatacgatt agcatcaaat ccgtatccat cttcttcatg tttctcatgt gaagttcctg
    67981 gattgattgg aagagatgga gaaggtgttg ctagactatt gtttggaaga gtcggttgcc
    68041 caatttgatt tgattttgga atgtaatgga aatgatcacc atgtcttaca atataagctg
    68101 tagccgtttc ttcaacgata tcttttggat taaaaatata accatcagat gctgaagaga
    68161 gctccttact tgtcgttaaa gaagaaggat tgcttgaaag actgcctaga ctagacacta
    68221 cttcattagg ttttgcattt gtagaaactg tagaaccagt tccactgata ggcaccattc
    68281 tggcaatctt ttcttctaag gcagaaagct tgctgtaagg aataaagtgg taatggtcgc
    68341 catgcggaat cgcaactcca tttggtgtac gactgataat cttagcaggg tcaaagacca
    68401 ggccatctga ttcactgtaa cgttgggcgc taggtgaatc atagagttcc ttcaaaagac
    68461 tctggagatt ttcagattta tttgctggct tgctagttga tccttttgct acagattgcg
    68521 tgttattgtc actagctgtt gaagaatagc ttaactgact cggttgcata ttttttccag
    68581 ccagatgtgc tttagctgct gctaattcac tagcagataa atcgcttttg ggaatgtagt
    68641 gatagtgacc tccatgagga acgatataag cattacccgt atcttcgata atatcagcta
    68701 gattaaagac ataaccatca tttgtcgtat atcgtccctg agaccttgct acagcaacat
    68761 tagagttaac cttctcatta tctttgacat gttcttgttt ttgacgattg atttcatctt
    68821 tagttcgaac attatcagca tgagctgcat ctttcaggta gacataatat tttccatcga
    68881 ccttgatgat ataaccaccc ttgacttcat tgacaatatc agcgtcttta agttgatagt
    68941 ttggatcctt catcaagagt tcttcactaa agagggcatc ataaggaact ttcccattat
    69001 agtaatgata gtggtcaccg tgtgacgtta catagccctg atctgtaatt ttgattacaa
    69061 tttgctcagc ctgaattcct tctttctggc taacctggtc tggtgtcaag ttttcacttt
    69121 tctgacttga ctggctgcca tccacataag agacacgatt attgtcctta ttttcctgcg
    69181 aacgatgctg gtttagtgca taggcacata gactcaagga tacgataaca gctgatccag
    69241 ctgctatata ttttttacta aatttcataa atccctcatt tcaataaatg atgaagtttt
    69301 ttctcaactt cttttacttt attaaatagt tttctaaacc ggttatttaa ccatttaatt
    69361 aaccagtaaa tagtttacta tttaaaatta cttttgtcaa gtttctgtta cgtttttcta
    69421 aaaaagagaa gtaacacgaa aggttacttc tccataaaat atgctccatt cattttacta
    69481 ctgtatcgga gccggttgac ttttttttaa caaagccaag agactatcta cttctgctga
    69541 aatagtgtta ttatctttcg ttccgagaag aagactactt tttagaccag tcaatgtctc
    69601 catagcattt tgtctaatac tagaatctgt tactttttct agcaaggcct ccgcctctgc
    69661 tatcttagcg ttaatcacag aatgctctac ttgaggaatt tcagtctcat ctgtagtatc
    69721 ttcagcttct tcctctgtct cttccgtatc agtgcttggt ttataaagat tatctgctga
    69781 aggatttaaa ccagcgtgat tctctttttc atcagattca gggtgagttg gctcacttac
    69841 ttcatcatgt cccttatctt catcaggttt actgtcttgg tctgccttat ttttacgaac
    69901 atggtc
//
LOCUS       DAVHLA010000005        67983 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVHLA010000005 DAVHLA010000000
VERSION     DAVHLA010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 67983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67983
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.005"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            <1..379
                     /locus_tag="VVO77_000401"
     CDS             <1..379
                     /locus_tag="VVO77_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
                     /protein_id="HEU5692467.1"
                     /translation="TGFYYGTPSENEQLFGARRKIPEYKFVAEVVSYDDATQTATIRQ
                     RNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELLTIKVPQPVQAGDM
                     VRALKEGLINLYKEDGTSVTVRA"
     gene            814..1605
                     /locus_tag="VVO77_000402"
     CDS             814..1605
                     /locus_tag="VVO77_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5692468.1"
                     /translation="MNFALNKGEIVGQVGRNGVGKSTLMKILVQNNQPTSGNIISSDN
                     VGYLIEEPKLFLSKTGLENLKYLSNLYGVDYNQERFRSLIQELDLTQSINKKVKTYSL
                     GTKQKLALLLTLVTEPDILILDEPTNGLDIESSQIVLSVLKNLALHENVGILISSHKL
                     EDIEEICERVLFLENGLLTFQKVGKDSHNFLFEIAFSSATDRDIFITKQEFGDIVQEE
                     GLRITMSGNIQSSELFKFFNENSIKVVDFETKKEMLKDIYLNRSK"
     gene            1621..2349
                     /locus_tag="VVO77_000403"
     CDS             1621..2349
                     /locus_tag="VVO77_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5692469.1"
                     /translation="MKLNKFNFIKENIRDLYSSGVIYLGLIISFIPPILLTFFILKTQ
                     GTSLGIKHISNFYAMLGMLMAVIHANRIISRDFSHNTISLFYNQQKNRMIYLLSNFLY
                     AISVSIIYALNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLVFGILVALLLFIPNILNTMMMNTSNDLFIKAIELLPFYSLPVFVTSNTMSISQ
                     YLVVITTIILLYFFTLKKSKKYSF"
     gene            2735..2944
                     /locus_tag="VVO77_000404"
     CDS             2735..2944
                     /locus_tag="VVO77_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU5692470.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            2934..3422
                     /locus_tag="VVO77_000405"
     CDS             2934..3422
                     /locus_tag="VVO77_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692471.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            3538..4998
                     /locus_tag="VVO77_000406"
     CDS             3538..4998
                     /locus_tag="VVO77_000406"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEU5692472.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISYMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            4995..5819
                     /gene="nadE"
                     /locus_tag="VVO77_000407"
     CDS             4995..5819
                     /gene="nadE"
                     /locus_tag="VVO77_000407"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEU5692473.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            6116..6667
                     /locus_tag="VVO77_000408"
     CDS             6116..6667
                     /locus_tag="VVO77_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU5692474.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGHGMMTEALKAVLDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            7381..8074
                     /locus_tag="VVO77_000409"
                     /pseudo
     CDS             7381..8074
                     /locus_tag="VVO77_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846497.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
     gene            8128..8517
                     /locus_tag="VVO77_000410"
     CDS             8128..8517
                     /locus_tag="VVO77_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU5692475.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(9178..10206)
                     /gene="queA"
                     /locus_tag="VVO77_000411"
     CDS             complement(9178..10206)
                     /gene="queA"
                     /locus_tag="VVO77_000411"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEU5692476.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            10357..11064
                     /locus_tag="VVO77_000412"
     CDS             10357..11064
                     /locus_tag="VVO77_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEU5692477.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            11142..11651
                     /locus_tag="VVO77_000413"
     CDS             11142..11651
                     /locus_tag="VVO77_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692478.1"
                     /translation="MNKEEFLKIKEAYKSARTEERKSIIGFITKKKDKEGNFLFTKSK
                     DKPYTTRNQYSGGGGNKKYTSGSRLSRPYDLSNHMWIDLSYKGNDILISLQSFDIDPN
                     SKELHVLYDRIGILFEQSKKIPIFKDCYTITKVSDAFLKMETTNWELPLSKADMEEMV
                     NYIINHYEE"
     gene            11731..11907
                     /locus_tag="VVO77_000414"
     CDS             11731..11907
                     /locus_tag="VVO77_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEU5692479.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            12037..12972
                     /locus_tag="VVO77_000415"
     CDS             12037..12972
                     /locus_tag="VVO77_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEU5692480.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINIADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            12965..13753
                     /locus_tag="VVO77_000416"
     CDS             12965..13753
                     /locus_tag="VVO77_000416"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEU5692481.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            13754..14137
                     /locus_tag="VVO77_000417"
     CDS             13754..14137
                     /locus_tag="VVO77_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEU5692482.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            14153..14542
                     /locus_tag="VVO77_000418"
     CDS             14153..14542
                     /locus_tag="VVO77_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEU5692483.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIHITEE"
     gene            14626..15756
                     /locus_tag="VVO77_000419"
     CDS             14626..15756
                     /locus_tag="VVO77_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEU5692484.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            15761..16498
                     /locus_tag="VVO77_000420"
     CDS             15761..16498
                     /locus_tag="VVO77_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEU5692485.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKV"
     gene            16509..17282
                     /locus_tag="VVO77_000421"
     CDS             16509..17282
                     /locus_tag="VVO77_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEU5692486.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            17272..17889
                     /locus_tag="VVO77_000422"
     CDS             17272..17889
                     /locus_tag="VVO77_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEU5692487.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLTLVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            18099..18500
                     /locus_tag="VVO77_000423"
     CDS             18099..18500
                     /locus_tag="VVO77_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEU5692488.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            18500..18778
                     /locus_tag="VVO77_000424"
     CDS             18500..18778
                     /locus_tag="VVO77_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEU5692489.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            18768..19541
                     /locus_tag="VVO77_000425"
     CDS             18768..19541
                     /locus_tag="VVO77_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEU5692490.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSSTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRSVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            19542..20846
                     /locus_tag="VVO77_000426"
     CDS             19542..20846
                     /locus_tag="VVO77_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEU5692491.1"
                     /translation="MQFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQTFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            21420..22298
                     /gene="pstS"
                     /locus_tag="VVO77_000427"
     CDS             21420..22298
                     /gene="pstS"
                     /locus_tag="VVO77_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEU5692492.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            22298..23215
                     /gene="pstC"
                     /locus_tag="VVO77_000428"
     CDS             22298..23215
                     /gene="pstC"
                     /locus_tag="VVO77_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEU5692493.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            23205..24089
                     /gene="pstA"
                     /locus_tag="VVO77_000429"
     CDS             23205..24089
                     /gene="pstA"
                     /locus_tag="VVO77_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEU5692494.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            24100..24903
                     /gene="pstB"
                     /locus_tag="VVO77_000430"
     CDS             24100..24903
                     /gene="pstB"
                     /locus_tag="VVO77_000430"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU5692495.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKDFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            24916..25674
                     /gene="pstB"
                     /locus_tag="VVO77_000431"
     CDS             24916..25674
                     /gene="pstB"
                     /locus_tag="VVO77_000431"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU5692496.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            25686..26339
                     /gene="phoU"
                     /locus_tag="VVO77_000432"
     CDS             25686..26339
                     /gene="phoU"
                     /locus_tag="VVO77_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEU5692497.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            26496..27311
                     /locus_tag="VVO77_000433"
     CDS             26496..27311
                     /locus_tag="VVO77_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU5692498.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKNEGTYQSYLEKAASLTEVEE"
     gene            complement(27331..28602)
                     /locus_tag="VVO77_000434"
     CDS             complement(27331..28602)
                     /locus_tag="VVO77_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEU5692499.1"
                     /translation="MKKQSKYKEVVSYLKNGIESERFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            28744..29475
                     /gene="budA"
                     /locus_tag="VVO77_000435"
     CDS             28744..29475
                     /gene="budA"
                     /locus_tag="VVO77_000435"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEU5692500.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            29485..30237
                     /locus_tag="VVO77_000436"
     CDS             29485..30237
                     /locus_tag="VVO77_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HEU5692501.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWLEKKR
                     SLEKADALAYGLGHGGLELIFLGLISLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            30349..31299
                     /gene="murB"
                     /locus_tag="VVO77_000437"
     CDS             30349..31299
                     /gene="murB"
                     /locus_tag="VVO77_000437"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEU5692502.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESLSVAKMYAGGFTPCKR"
     gene            31358..32515
                     /locus_tag="VVO77_000438"
     CDS             31358..32515
                     /locus_tag="VVO77_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5692503.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFEPEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            32496..33302
                     /locus_tag="VVO77_000439"
     CDS             32496..33302
                     /locus_tag="VVO77_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5692504.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            33299..34072
                     /locus_tag="VVO77_000440"
     CDS             33299..34072
                     /locus_tag="VVO77_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5692505.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIIAGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            34069..35139
                     /locus_tag="VVO77_000441"
     CDS             34069..35139
                     /locus_tag="VVO77_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU5692506.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYEAFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKLEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDPQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQDS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            35400..35639
                     /locus_tag="VVO77_000442"
     CDS             35400..35639
                     /locus_tag="VVO77_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692507.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTAILFHLNDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            35914..36399
                     /locus_tag="VVO77_000443"
     CDS             35914..36399
                     /locus_tag="VVO77_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEU5692508.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            36421..39039
                     /gene="alaS"
                     /locus_tag="VVO77_000444"
     CDS             36421..39039
                     /gene="alaS"
                     /locus_tag="VVO77_000444"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEU5692509.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNTSQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKIVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVDNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAIAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(39129..40583)
                     /locus_tag="VVO77_000445"
     CDS             complement(39129..40583)
                     /locus_tag="VVO77_000445"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEU5692510.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKEQGIQPMADVVL
                     NHKAAADNREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNGFHWHWYHFT
                     GTDYDAKRSKSGIYLIQGDNKGWANKELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            40762..41511
                     /locus_tag="VVO77_000446"
     CDS             40762..41511
                     /locus_tag="VVO77_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5692511.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLTSSDLETSLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSAPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVEN
                     LRKDHPDQFLESIYLSLAGRKEEVADASQGH"
     gene            41492..43126
                     /locus_tag="VVO77_000447"
     CDS             41492..43126
                     /locus_tag="VVO77_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692512.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMLICFSNIAIHFPFEEMPIYFSSMVAILLVLAFSTSFTAFYNVFYESK
                     DLASYRPYAFKESEIIMAKGLSVLLPALTGIVPILAYFLALYISLAPSLWLGLPLMLL
                     SLTLLFVSVTLVTVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEALVGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVITVLFTSAFLPYL
                     MMISLISKIRDSQIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIFAVQSFLPVLTLLGLSLYLGLPILSMIYLLVVWIIASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAINLGVGALIVLLALAIFGYHYYLSRILAEIEKR"
     gene            43811..44974
                     /locus_tag="VVO77_000448"
     CDS             43811..44974
                     /locus_tag="VVO77_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEU5692513.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQAFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            44971..45648
                     /locus_tag="VVO77_000449"
     CDS             44971..45648
                     /locus_tag="VVO77_000449"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEU5692514.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            45638..46492
                     /locus_tag="VVO77_000450"
     CDS             45638..46492
                     /locus_tag="VVO77_000450"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEU5692515.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDELSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            46511..47578
                     /locus_tag="VVO77_000451"
     CDS             46511..47578
                     /locus_tag="VVO77_000451"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEU5692516.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     IAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSAIIHPVSLEEMKDYLVK"
     gene            47588..48754
                     /gene="aroC"
                     /locus_tag="VVO77_000452"
     CDS             47588..48754
                     /gene="aroC"
                     /locus_tag="VVO77_000452"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEU5692517.1"
                     /translation="MRYLTAGESHGPRLTAIIDGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIENDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            48764..49867
                     /locus_tag="VVO77_000453"
     CDS             48764..49867
                     /locus_tag="VVO77_000453"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEU5692518.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSEIILDRIEDFKERLEAIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            49878..50216
                     /locus_tag="VVO77_000454"
     CDS             49878..50216
                     /locus_tag="VVO77_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEU5692519.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTDY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            50308..51591
                     /gene="aroA"
                     /locus_tag="VVO77_000455"
     CDS             50308..51591
                     /gene="aroA"
                     /locus_tag="VVO77_000455"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEU5692520.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLSPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKEYTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIAPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEICGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            51584..52060
                     /locus_tag="VVO77_000456"
     CDS             51584..52060
                     /locus_tag="VVO77_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEU5692521.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGESAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIVADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            52057..52905
                     /gene="pheA"
                     /locus_tag="VVO77_000457"
     CDS             52057..52905
                     /gene="pheA"
                     /locus_tag="VVO77_000457"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEU5692522.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            52902..54176
                     /gene="psr"
                     /locus_tag="VVO77_000458"
     CDS             52902..54176
                     /gene="psr"
                     /locus_tag="VVO77_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEU5692523.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     RNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSSPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            54455..55300
                     /locus_tag="VVO77_000459"
     CDS             54455..55300
                     /locus_tag="VVO77_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU5692524.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGTLR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSYKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKDPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            55290..56393
                     /locus_tag="VVO77_000460"
     CDS             55290..56393
                     /locus_tag="VVO77_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEU5692525.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLARRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            56395..57381
                     /locus_tag="VVO77_000461"
     CDS             56395..57381
                     /locus_tag="VVO77_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU5692526.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQIYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            57397..58830
                     /locus_tag="VVO77_000462"
     CDS             57397..58830
                     /locus_tag="VVO77_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEU5692527.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFIAKMLTKEN"
     gene            58859..59893
                     /locus_tag="VVO77_000463"
     CDS             58859..59893
                     /locus_tag="VVO77_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEU5692528.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            60035..60772
                     /gene="mecA"
                     /locus_tag="VVO77_000464"
     CDS             60035..60772
                     /gene="mecA"
                     /locus_tag="VVO77_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEU5692529.1"
                     /translation="MKMKQISDTTLKITISLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFAEDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            60923..62209
                     /locus_tag="VVO77_000465"
     CDS             60923..62209
                     /locus_tag="VVO77_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEU5692530.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVVHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILAPDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            62211..63080
                     /locus_tag="VVO77_000466"
     CDS             62211..63080
                     /locus_tag="VVO77_000466"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEU5692531.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            63330..64268
                     /gene="msrB"
                     /locus_tag="VVO77_000467"
     CDS             63330..64268
                     /gene="msrB"
                     /locus_tag="VVO77_000467"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEU5692532.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            64326..66050
                     /locus_tag="VVO77_000468"
     CDS             64326..66050
                     /locus_tag="VVO77_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5692533.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISTELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISVKRIEEVFVEAPEDIHSELEQKQATRDKVLQV
                     QELTFTYPDAAQPSLRYISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGFNQEVSDQELWQALEIAQAK
                     DFVSEKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYCEIN
                     ASQHGKED"
     gene            66052..67803
                     /locus_tag="VVO77_000469"
     CDS             66052..67803
                     /locus_tag="VVO77_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5692534.1"
                     /translation="MKRQTVNQTLKRLAVDLASHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKKSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGSA
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     TSDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKVAIVGPTGAGKSTLINLLMRF
                     YPISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVI
                     AAAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATS
                     SIDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMD
                     RKGKYYQMQKAAAFSSE"
BASE COUNT        19836 a        12585 c        15274 g        20288 t
ORIGIN      
        1 tacaggattt tactatggta caccatctga aaatgagcag ttgtttggtg ctcgtcgtaa
       61 aattcctgag tacaagtttg tcgctgaagt ggtttcttat gatgatgcga cacaaacagc
      121 aaccattcgt caacggaacg tcattaacga aggggaccaa gttgagtttt atggtccagg
      181 tttccgtcat tttgaaacct atattgaaga tttgcatgat gccaaaggaa ataaaatcga
      241 ccgcgctcca aatccaatgg aactattgac tattaaagtc ccacaacctg ttcaagctgg
      301 agacatggtt cgagctctta aagaggggct tatcaatctt tataaggaag atggaaccag
      361 cgtcacagtt cgtgcttaat gtagttgttt agttttaaaa aattatgcaa agctccatat
      421 acaacactta aacgagatta aagaatggcg aaatcccctg atgcgcaaga gattagctgt
      481 cttttttatt ttttaagtga taaagtcgga gcttaggtat caaagcctat caaattaaac
      541 aaagaagcga tgtcttagat attttgaaaa aaattaataa gcagaaaact ctctattatt
      601 ttgttgtata gagttttttg ttaataaaat ttcacaaaat gacatttata tattgcatta
      661 agttagatat atgatataat attgttaaaa agaggcgcaa ctttttaaaa ttaatgagaa
      721 tcaaagagaa aaccaataat attaatggag gaataaaaaa tgtaagttat aaatgtaagt
      781 aagcattatg gtcattcaat cattctcaaa gacataaatt ttgcacttaa caagggtgaa
      841 attgttggtc aagtagggag aaatggagtt ggtaagagta cgttgatgaa aattcttgtt
      901 cagaataatc aaccgacttc aggtaatatt ataagcagtg ataatgttgg gtatttaatc
      961 gaagaaccaa aattattttt atctaaaaca ggtttagaga atttaaaata tttgtcaaat
     1021 ttatatggtg ttgactacaa tcaagaaaga tttagaagtt tgatccaaga gttagatttg
     1081 actcagtcta ttaataaaaa agtaaagacc tattctttgg gtacaaaaca aaaattagct
     1141 ttgcttctaa ctctcgttac ggaacctgat atattgattt tagatgaacc gactaatggt
     1201 ttagatattg aatcatcaca aatagtttta tcggttctaa aaaatttagc tttacatgaa
     1261 aatgtgggaa ttttaatatc gagtcataaa ttagaagata ttgaagaaat ttgtgagagg
     1321 gttcttttct tggagaacgg gcttttgaca tttcaaaaag taggaaaaga tagtcataat
     1381 ttcttgtttg agatagcttt ttcatcagct acagatagag acattttcat taccaaacaa
     1441 gaatttgggg atattgttca ggaagaggga ctgagaatta ctatgtctgg gaatattcaa
     1501 agtagtgagc tttttaaatt ttttaacgaa aactctatta aagtagttga ttttgaaact
     1561 aaaaaagaga tgcttaaaga tatttatcta aatcgttcaa aataaaggaa ggttataatc
     1621 atgaaattaa ataaatttaa ttttattaag gaaaatataa gggatttata ttcatcaggc
     1681 gtaatatatc tcggtttgat tatctcgttt ataccgccga tattgcttac attctttatt
     1741 ctaaagactc aagggacatc gcttggtatt aagcatattt caaactttta tgctatgctc
     1801 ggtatgttaa tggctgttat acatgctaac cgaattatta gcagggattt ttcccacaat
     1861 acgatcagtt tattttataa tcaacagaaa aatcggatga tttacctctt gtctaatttt
     1921 ctatatgcca tctcagtttc cattatttat gctttgaatg gcattgtgtt actagtcata
     1981 gtaagtaaat tgggtattcc aggtgattta ggattagatt ttatagtagc tattgtagtc
     2041 aatacaattt tgttagtcct gttttatttt ctattatctt acattttcta tttatacaaa
     2101 ttgaaaagtg gcttggtatt tggtatttta gtagctttac tactctttat ccctaatata
     2161 ttaaatacga tgatgatgaa tactagtaat gatttgttta tcaaagcaat tgaacttctt
     2221 cctttttatt ctttacctgt atttgtgact tcaaatacga tgtctattag tcagtatctt
     2281 gtggtaatca ctacaatcat tttattgtac tttttcactc tcaagaaaag caagaagtat
     2341 tcattttagt ttcatttagt attattttgc atacctaaaa tacaataaaa aaatcagtca
     2401 tcttggtatg ctcctgcttt cactattcaa cacgtttttg acttatacta ggctcatttc
     2461 caaaagcatt atataatagt gatatgaaac caactaaact aaacaagaaa tataagcaat
     2521 aaaaactcgt ttaaaagatt ctactaaagc taatactaaa taaaaataaa agagtaaact
     2581 aggaagttta tttcaaacaa cctaaaatac tgattttcgg ctgaagataa tactggagtg
     2641 caaattaatg gggttataat aaatagctga tagcttgtgt tggttttgga ttttttaaga
     2701 gtagatgagt attaaaacta taaggaggac gaaggtggct aaaaatttaa aattaaaatt
     2761 agctcgggta gagcgtgatt taacacaagg tcaactggca gaggctgtcg gggtgacacg
     2821 ccagactatt ggtttgatag aggcgggaaa atacaatccc agtctctcgc tctgccagtc
     2881 tatttgcaga tgtttaggga aaaccctaga ccaactattt tgggaggaag aagatgaaaa
     2941 atagatttta ttattatcaa ttactagacg aaagagaaga acaactgttc aataaagcgg
     3001 gctctgaaag tttctatatc tgcattgctt tgtcgctcct atcttatatc atttcagtat
     3061 tagcaccaag cctttttaat tctaatatgc tgctaatcgt tatcatcata gggacatttt
     3121 actttttcaa tcgtgcccgt tatctgggag tgacctacta tagtcgtttt cattttacga
     3181 ttttgggttg ttttttccta accttggcta ttacggctct tttgatgttg cagaattatc
     3241 aattcaacat agaaatttat cagcacaatc ctttgaattt taaatacctg tctgcttggg
     3301 tcattactta tgtcatttac cttccgtggg tctttattgg caatcttggt cttaagagct
     3361 atggcgaatg ggctcagaaa aaatttgaac aagatatgga tgaattggag agtggagaat
     3421 agcttgttac tcttttctca atccagctaa aatgtgatat aatagtatta atttattgga
     3481 atacatgaaa gttcttgaaa attttcatgg gtttctagct aaggaagtag gaaaagtatg
     3541 tatccagatg atagtttgac attgcacacg gacttgtacc agatcaacat gatgcaggtt
     3601 tactttgacc aagggattca caataagaag gcggtctttg aggtgtattt ccgccaacag
     3661 ccttttaaga acggctatgc ggtttttgca ggtttggaaa gaattgtgaa ctatcttgaa
     3721 gacttgcgtt tttcagatag tgatatagcc tatttggagt cgcttggtta tcatggggcg
     3781 ttcttggatt accttcgcaa tttcaagttg gagttgaccg ttcgttctgc ccaagaaggg
     3841 gatttggttt ttgctaatga accgattgtg caggtggaag gacctctagc ccaatgtcag
     3901 ttggtcgaaa cggctctttt gaacatcgtc aactaccaga ccttggtggc gacgaaggca
     3961 gctcgtattc gttcggttat cgaagatgaa cccttgatgg agtttgggac acgtcgggct
     4021 caagaaatgg atgcggccat ctggggaaca cgcgcagctg tgattggtgg cgccaatgga
     4081 accagcaacg tgcgtgcggg taagctcttt gacattcctg ttttgggaac ccatgcccat
     4141 gccttggtac aggtttatgg aaatgactat gaagctttca aggcttacgc tgcgacccac
     4201 aaaaattgtg tctttcttgt ggatacctat gacacccttc gcatcggtgt accagctgcc
     4261 attcaggtgg cgcgtgagct gggtgatcag attaacttta tgggtgtgcg gattgactct
     4321 ggggatattg cctacatttc taagaaagtc cgtcagcaac tggacgaggc tggatttaca
     4381 gaggctaaga tttatgcttc taatgatttg gacgaaaata ctatcctcaa cctcaagatg
     4441 caaaaggcca agattgatgt ctggggcgtg ggtaccaagc tgattacagc atatgaccag
     4501 ccagctcttg gggcggttta caagattgtt gcaatcgaag atgaaactgg tcagatgcgc
     4561 aatacgatta agctgtctaa taatgctgaa aaagtctcta cgccaggtaa gaagcaggtg
     4621 tggcgcatta ccagtcgtga aaaaggtaag tcagaaggtg actacatcac ttatgatggt
     4681 gtggatatta gctacatgac agaaatcaag atgttccatc cgacctatac atacatcaag
     4741 aagacggttc gtaattttga tgccgttcct ctcttggtgg atatcttcaa agaaggaata
     4801 ttagtttaca acttgcctag tttgactgac attcaggatt atgcccgtaa agaatttgac
     4861 aagttgtggg atgagtataa gcgtgtgctc aatccgcagc actatccagt ggatttggcg
     4921 cgtgatgtat ggcaagataa gatggacttg attgataaga tgcgcaagga agcccttggt
     4981 gaaggagaag aagaatgagt ttgcaagaaa cgattatcca agagctgggt gtcaaaccag
     5041 tgattgatgc ccaggaagaa atccgtcgtt ctattgattt cttaaaaaga tatctgaaaa
     5101 aacatccctt cctaaaaacc tttgtactag ggatttctgg gggacaagac tcaaccttgg
     5161 cagggcgttt ggcgcaatta gctatggaag aactgcgagc tgaaacggga gacgacagct
     5221 acaaatttat cgctgtccgc ctgccatacg gagtgcaagc tgatgaagca gatgctcaaa
     5281 aagccctagc cttcatccag ccagatgtca gcttggttgt gaatatcaag gaatcagctg
     5341 atgccatgac agctgcagtt gaagcgacag gtagtcctgt ttcagacttc aacaagggga
     5401 atatcaaggc acgttgccgt atgattgctc agtatgccct tgctggttcc catagcggag
     5461 cggtcattgg aacagaccac gccgcggaaa atatcacagg tttctttacc aagtttggtg
     5521 acggcggtgc ggatattctc cctctttacc gcctcaataa acgccaagga aaacagctct
     5581 tgcagaaact tggcgcagag ccagcccttt atgaaaaaat cccaacggca gacctagaag
     5641 aagataaacc aggcctagct gacgaagtcg cacttggagt cacctatgca gagattgacg
     5701 attacctaga aggcaaaaca atcagcccag aagctcaagc gaccattgaa aactggtggc
     5761 acaaaggcca acacaaacgc cacttaccca tcaccgtatt tgatgacttt tgggagtaaa
     5821 aacctccatt ggaggttttt accctgagcc tagaaatgag aaagtgagag aaagtccggg
     5881 ggatcttgaa ccccgagttt agaaataaga aaatgaggca gattcggtaa ctcgaagagt
     5941 tcgatttcat cgtcttaccc ctgcaacgat gactaggttt gaaaaagctt gctagatcgc
     6001 atttcaaacc aggcagcgac tgcgtcaaga aattagaaga caaactcgtt ttctagctgt
     6061 tactgagttg agtcttttta ctacgagcat agaaataagg aagtgaggta gcatcatgaa
     6121 atctatcggt acgcaaatat tacagacaga acgtttgatt ttaagaagat ttgtggagag
     6181 tgatgcagaa gccatgtttc aaaattgggc ttcatccgct gagaatttga cctatgttac
     6241 ctgggatccc catcctgatg tcgaaatcac tcgaaactcg attcgcaatt gggttgcttc
     6301 ctatactaat ctcaactatt acaaatgggc catttgtcta aaagaaaacc cagagcaagt
     6361 gataggagat atcagcatcg ttaagataga cgaggctgat ttaagctgtg aaatcggcta
     6421 tgtgctaggc aaggcttact ggggacatgg tatgatgaca gaggccttga aagctgtctt
     6481 ggacttttgt tttactcaag caggttttca aaaggtcaga gcacgttatg ccagtctcaa
     6541 cccagcttca ggtcgtgtca tggaaaaggc tggaatgtcc tatctacaaa ccattgttaa
     6601 tggtgtagag agaaaaggct atcttgcgga tcttatttat tatggtataa gtagggaaga
     6661 atgttgaatt ctattttctg tttctatcga agtcaactat ttattgtaaa tataataatt
     6721 agcattccaa gtttatttga aactttaaaa tagcatattg attagtacaa gacagatgtt
     6781 ctagttcctt ctttaatctg gtttagtatt agttaaaaaa tcgcttgaag cttgtaacta
     6841 agagggagct aatcgactag gttctccagc cgaacaggtg gtaatgtact ttttatagtg
     6901 taatcctagc tgttgttaaa tttaaaatag aatcctctat cgagttaggg aattaaattc
     6961 aaccaatttt atttatgttt ttctatcaaa ttatctaata ttaaaatagt ctcattctga
     7021 tgagaaaact attctattta tactgcatag ttgtataagg aatgatgaaa gatgagtgaa
     7081 agttatcaag ttggaatgtt tgtatctaaa tatattagca tgtatttaga taagatgtct
     7141 gcaatccttt atatatgaga ttgattacga tatagttaaa gtgttagttc aataatcaat
     7201 atatcattct aagtctattt tatatataaa gtatattgtt taacgtttga tagaaaagat
     7261 gctatactag aagtaggatg taatggcaaa atctaatact aataagcgct atgcaatacg
     7321 taaactcgga aagatttttg gttctgcggt aatcgggcta actttatttt taggaggaat
     7381 ctgaatacaa gttttgttca tgctgctgat gggattcaat atgtcagaga tgatactaga
     7441 gataaagaag agggaataga gtatgatgac gctgacaatg gggatattat tgtaaaagta
     7501 gcgactaaac ctaaggtagt aaccaagaaa atttcaagta cgcgaattcg ttatgaaaaa
     7561 gatgaaacaa aagaccgtag tgaaaatcct gttacaattg atggagagga tggctatgta
     7621 actacgacaa ggacctacga tgttaatcca gagactggtt atgttaccga acaggttact
     7681 gttgatagaa aagaagccac ggatacagtt atcaaagttc cagctaaaag caaggttgaa
     7741 gaagttcttg ttccatttgc tactaaatat gaagcagaca atgacctttc tgcaggacag
     7801 gagcaagaga ttactctagg aaagaatggg aaaacagtta caacgataac ttataatgta
     7861 gatggaaaga gtggacaagt aactgagagt actttaagtc aaaaaaaaag actctcaaac
     7921 aagagttgtt aaaaaaggaa ccaagcccca agttcttgtc caagaaattc caatcgaaac
     7981 aaaatatctc gatggcccaa ctcttgataa aagtcaagaa gtagaagaag taggagaaat
     8041 tggtaaatta ctcttactac aatctatact gtagatgaac gtgatggaac aattgaagaa
     8101 actacttctc gtcaaattac taaagagatg gtaaaaagac gtataaggag agggacgaga
     8161 gaacctgaaa aagttgttgt tcctgagcaa tcatctattc cttcgtatcc tgtatctgtt
     8221 acatctaacc aaggaacaga tgtagcagta gaaccagcta aagcagttgc tccaacaaca
     8281 gactggaaac aagaaaatgg tatgtggtat ttttataata ctgatggttc catggcaaca
     8341 ggttgggtac aagttaatgg ttcatggtac tacctcaaca gcaacggttc tatgaaagtc
     8401 aatcaatggt tccaagttgg tggtaaatgg tattatgtaa atgcatcggg tgagttagcg
     8461 gtcaatacaa gtatagatgg ctatagagtc aatgataatg gtgaatgggt gcgttaacag
     8521 attcctccct gcgacaaaat tgataatagt atgtctgaat atataattat atataaaaag
     8581 ctatagataa ggtcatctta tagcgactat aaaaaagtga acaagcctag tcttctgtac
     8641 attagaattc agatttgttc actttttgtt taatactcaa tgaaaatcaa agagcaaact
     8701 agaaaactag tcgcaggttg ctcaaagtac tgctttgagg ttgtagatag aactgacgaa
     8761 gtcagtcaca tatataatcc aaggtgacgt tgacgcggtt tgaagagatt tttgaagagt
     8821 ataagtcttt gattttgaga ctaaggagag tcagggtcaa agtagtgaat gattctgaaa
     8881 taactcataa tagtctcttg agaggacaga taagagtaac aaatatggtg ctactcatgt
     8941 gtcttgcatt ttgatttaca aacagcgaag aaaatatagg aagctgaaat aaaatataga
     9001 tgaatcaatt tggagagtca acgcaatcta tggcaatatt ttcgaagcta gggggaagca
     9061 ttttaatttc aatgtactag gcctcttcta cagctagcta gagtttcaat tgtagatgtt
     9121 ctttgaaata atatcttagc gatttattgg tattagaaga tttagagaaa ttctttctca
     9181 ataaataaac atggcgtcac caaaactgaa gaagcggtag tgttcttgga tggcatggtg
     9241 gtaggcatct aagactaatt cacggcctgc aaaggcagaa accaacatga ccagagttga
     9301 ttttggcagg tggaagttgg ttgagaaggc atccacgacc ttccactcat acccaggttt
     9361 gataaagata ttggtccaac cagaatctgc ttggatttgc ccatcaaact tggaaccaat
     9421 agtttccaag gtgcggatag aagtggttcc gacagcgatg acacgaccac cattttcttt
     9481 gacagagcga agggtggcag cagcttcctc agaaagttga tagaactctg agtgcatttc
     9541 gtgttcgtcc agattatcca cagaaacagg tctaaaggtt ccgagtccga catggagagt
     9601 cagatagact agatgaacac ccttagcttg gatttctgcc agcagttctt tggtgaagtg
     9661 aagaccagca gtcggtgctg cagcagagcc gctttccttg gcgtagacgg tttgataacg
     9721 ttcacggtca tctaattttt cgtggatata aggtggcaga ggcatttctc ccagactttc
     9781 caagacttct aggaaaattc cttggtattc aaagcggaca atgcgtcccc cgtgggtcaa
     9841 ttcttctgta acgacagcgc tgaggcggcc atcaccaaag ctgatacgag taccgacctt
     9901 gaggcgtttg gcaggtttag ccagaacttc ccactcgtct ccactagtgt tcttaaggag
     9961 gagaagttcc acatgacctc ctgtctccac tttttgacca tagaggcggg cagggagaac
    10021 tcgggtgtcg ttcatgacaa gggcatcacc aggttccagc atatcaataa tagagtggaa
    10081 gtgtttatct tgcatttctc ctgtctcacg gttgacgatg aggagtttgg aggcatcacg
    10141 tttttcaagg ggcgtttggg caatcaattc ctctggcaag tggaaatcaa aatcagctgt
    10201 attcatatat ttgttcattc tttctaagtt ctaatcctat ccattataac acgtttcaag
    10261 tttggacgct ctttttttag aaattaaatc gttttcactt gacaaaaatt ggtctatacc
    10321 atataataaa tatagacaga aatggaggat gaaaagatga aagttattaa agttgaaaac
    10381 caagttcaag gtggaaaagt tgcttttgag attttgaagg aaaaattggc taatggagct
    10441 caaactctag gacttgcgac aggaagtagc ccacttgaat tttacaagga aattgttgag
    10501 agtgaccttg atttttcaaa tctaaccagt gtcaaccttg atgagtatgt gggccttgat
    10561 ggggacaatc cacagtctta tcgttacttc atgcaagaaa acttgttcaa ccaaaaacca
    10621 tttaaagaaa gtttcttgcc tcgtggtgtt aaggacaatg ctgaagctga agttgaacgc
    10681 tacaaccaaa ttttggctga ccatccagtt gacctccaaa tcttgggaat cggtcgcaat
    10741 gggcatatcg gctttaatga gcctggtact ccatttgaca gtcaaacgca tctagtagaa
    10801 cttgaccagt ctactatcga agccaatgca cgcttctttg ccaagattga agacgtccca
    10861 acccaagcta tttcaatggg gattaaaaac attttggatg ccaagtctat tattcttttt
    10921 gcttacggtg agtcgaaagc agaagccatt gccggaacag tatctggccc agtgactgag
    10981 aacctacctg caagtagcct ccaaaatcac cctgatgtaa ccatcatcgc agatgctgaa
    11041 gcgcttagct tactcgaaaa ataaaaagta taagaaccgc ttgctctttg gagtgagtgg
    11101 ttttagacat ataaaacttc aacttaactt taggaggaca catgaataaa gaagaatttt
    11161 taaaaataaa agaagcatat aagagtgcta gaacggaaga aagaaaaagt ataataggct
    11221 tcattacaaa aaagaaagat aaggagggga attttctttt tactaagtca aaagataaac
    11281 catataccac aagaaatcaa tattcaggag gcggaggaaa taaaaagtac acctcgggta
    11341 gtagattatc taggccatat gatttatcaa atcacatgtg gattgatttg tcatataaag
    11401 gaaatgacat cttaatctct ttacagtctt ttgatattga tccaaatagt aaagaacttc
    11461 acgtcttata tgatagaata ggcatcttat ttgaacaatc taaaaaaatt ccaattttta
    11521 aagattgcta tacaataact aaagtcagtg atgcttttct taaaatggaa acaacaaact
    11581 gggaattacc tttatctaaa gcagatatgg aagagatggt gaactatatt attaatcatt
    11641 atgaagaata aaaaacttag tttcctcttg acaattattc cttttacgtg tagaatgaaa
    11701 tagatattga acttgaaggg agtgaaaaaa atgtctaaaa cagtagtacg taagaatgaa
    11761 tctcttgacg acgcacttcg ccgtttcaaa cgtgcggtta ctaaagctgg tactcttcaa
    11821 gaaacacgca aacgtgaatt ctatgaaaaa ccttctgtaa aacgtaaacg taaatcagaa
    11881 gtagctcgta aacgtaaaaa attctaattg aaatgaaagg ctagagaaat ctagtccttt
    11941 ttcttttaaa taaatactcc aaagcctgca aaaatctgaa acttcctcct acaatttgat
    12001 ataatagaga gaagaactca tttgaaggag gaaatgatgt cggttttagt aaaagaagtg
    12061 attgaaaagc ttagactaga cattgtctat ggtgaaccag aattgcttga aaaggaaatc
    12121 aatatagcgg atattacgcg acctggtctt gaaatgacag gctattttga ctactataca
    12181 ccagagcgga ttcaactttt ggggatgaag gagtggtctt atctgatcag catgccttcc
    12241 aacagccgtt atgaagtttt gaaaaaaatg tttctacctg agacaccagc agtcattgtt
    12301 gcccgtggtt tggtggttcc agaggagatg ttaaaggctg ctagagaatg taagattgct
    12361 attttaacca gccgtgcagc taccagtcgt ttatctggag agttatctag ctatctggat
    12421 tctcgtttgg cagaacgtac cagtgtgcac ggtgtcttga tggatattta tgggatgggc
    12481 gtcttgattc agggagatag tggaattggt aagagtgaga caggtcttga gcttgtcaaa
    12541 cgtggtcacc gtttggtagc cgatgaccgt gtcgatatct ttgccaagga tgagattact
    12601 ctctggggtg aaccagctga aattttgaaa cacttgattg aaattcgtgg ggttggtatt
    12661 atcgatgtta tgagtctcta cggtgcgagt gctgtcaagg attcttcaca ggttcagctt
    12721 gctgtctatt tggaaaatta cgatacgcat aagacctttg atcgtcttgg aaacaatgca
    12781 gaggaacttg aagtttctgg cgtagccatt cctcgtattc gtattccagt taaaacaggt
    12841 cgtaatatct ctgttgtgat tgaggcagct gccatgaatt atcgtgccaa ggaaatgggc
    12901 tttgatgcga cccgtttgtt cgacgaacga ctgacaagtc tcatcgctcg aaatgaggtg
    12961 caaaatgctt gatccaattg ctattcaact aggaccccta gccattcgtt ggtatgcctt
    13021 atgtattgtg acaggcttga ttcttgcggt ttatttgacc atgaaagaag cacctagaaa
    13081 gaagatcata ccagacgata ttttagattt tatcttagta gcctttccct tggctatttt
    13141 aggagctcgt ctctactatg ttattttccg atttgattac tatagtcaga atttaggaga
    13201 gatttttgcc atttggaatg gtggtttggc catttacggt ggtttgataa ctggggctct
    13261 tgtgctctat atctttgctg accgtaaact catcaatact tgggattttc tagatattgc
    13321 ggcgcctagc gttatgattg ctcaaagttt ggggcgttgg ggtaatttct ttaaccaaga
    13381 agcttatggt gcaacagtgg ataatctgga ttatctacct ggctttatcc gtgaccagat
    13441 gtatattgag gggagctacc gtcaaccgac tttcctttat gagtctctat ggaatctgct
    13501 tggctttgcc ttgattctga tttttagacg gaaatggaag agtctcagac gaggtcatat
    13561 cacggccttt tacttgattt ggtatggttt cggtcgtatg gtcatcgaag gtatgcgaac
    13621 agatagtctc atgttcttcg gacttcgagt gtcccaatgg ctgtcagttg tccttatcgg
    13681 tctcggtata atgatcgtta tttatcaaaa tcgaaagaag gccccttact atattacaga
    13741 ggaggaaaac taaatgttag aagttgcata tattcttgtt gccttagctt tgattgtctt
    13801 tttggtctat ctgatcatta ctgtacaaaa gcttggtcgt gtcatcgatg aaacagaaaa
    13861 gacgattaaa accttgactt cagatgtgga tgtgaccttg catcacacca atgagttgtt
    13921 ggctaaggtc aatgtcttgg cagatgatat caatgtcaag gtggctacga ttgatccact
    13981 cttcagtgct gttgcagatt tatctctatc tgtttcagac ctcaatgacc atgcgcgtgt
    14041 cttgagcaag aaagcttcat cagctggttc aaaaacactc aagactggtg caagtctgtc
    14101 agctcttcgt cttgcaagta aatttttcaa aaaataaaaa aggagaatcc ttatgggtaa
    14161 attatcctca atccttttag gaacggtttc aggtgcagct cttgccttgt ttttaacaag
    14221 tgataagggc aaacaagttt gcagtcaggc tcaagatttt ctagatgatt tgagagaaga
    14281 tccggagtat gccaaggagc aagtctgtga aaaactgaca gaagttaagg agcaggctac
    14341 agattttgtt ctgaaaacaa aagaacaggt tgagtcaggt gaaatcactg tggacagtat
    14401 acttgctcaa gctaaatcct atgcttttca agcgacagaa gcatcaaaaa atcaattaaa
    14461 taatctcaag gaacaatggc aagaaaaagc cgaagctctt gatgactcag aagagattgt
    14521 gattcatata acagaagaat aaaccatcac catctccgga cggactatgt atctggggat
    14581 ggtgattttt atctggaatc tagtctttgt ggtataataa ttactatgca gaaaaaacca
    14641 acgtcagcct atgtgcacat cccattttgt acccagattt gttattattg tgatttttca
    14701 aaggtcttca tcaaaaatca gccagtcgac agctatttag agcatctgct ggaagagttt
    14761 cgttcttatg atattgaaaa gttgtcaacc ctttatatcg gtggtggaac accgacagcc
    14821 ctgtcggctc cgcaactgga ggtgttactg aatggcttga ctaaaaactt ggatttgtct
    14881 gtcttggaag agttgaccat tgaagccaat ccaggcgatt tggatgcgga taagatagct
    14941 gttttgaaaa attcggctgt caatcgtgtt tcgctaggtg tccagacctt tgatgataag
    15001 atgttgaaaa agattgggcg cagtcatttg gagaaggata tttatgaaaa tatcgatcgc
    15061 ctgaaactgg ctggttttga caacatctcc attgatttga tttatgctct gcctggtcag
    15121 accatggagc aagtaaagga aaatgtggct aaagccattg gattggatat tccccacatg
    15181 agtttgtata gtttgatttt agaaaaccat acggtcttta tgaaccggat gcgacgtggg
    15241 aaattgcctc tgcctaagga ggaactagaa gcggagatgt ttgagtacat cattgcagag
    15301 ctggagcgag cgggttttga gcattatgag atttctaatt tctccaaacc cggttttgaa
    15361 agtcgtcata atctcatgta ctgggacaat gctgaatact atggtattgg tgcaggggca
    15421 tctggttatg tcaatggagt acgctataaa aatcatggtc ccattcgtca ttatctcagt
    15481 gcggttgagg aaggcaatgc ttgtattaca gaagatcacc tgagtcaaaa ggagcaaatg
    15541 gaagaagaaa tgttcttggg actccgcaag aaatccgggg tttccatggc gcgatttgag
    15601 gaaaaatttg gacagtcttt tgctggactt tatggagaaa ttgtcagaga tttggttcaa
    15661 caaggcctca tgcagattga gggtgaccac gttcgcatga caaagagagg tctctttttg
    15721 ggagatactg tagcagaacg atttattttg gagtaggatc atgggcttaa cttatcaaat
    15781 gaaaatgaaa attccttttg atatggctga tatgaacggt catatcaaac ttccagatgt
    15841 gattttgctg tcactgcaag tttcagggat gcaatcgatt gaactgggag ttagtgataa
    15901 ggccattttg gaagactata atctggtctg gattatcgca gaatatgata ttgaggtggt
    15961 tcgtttgcct cgttttgcgg aagaaattac catcgaaacg gaagccttga gctacaatcg
    16021 acttttttgc taccgtcgct ttactattta taatgaagcg gggcaggagc tcatccatat
    16081 gatggcgacc tttgttctca tggaccgcga cagtcgaaaa gtccatgctg ttgaacctga
    16141 gattgtggct ccttaccagt ctgattttga taaaaaactt atccgtggac cgaagtatga
    16201 atccttggaa gagccgatca gcaaggatta ccatgttcgt ttttacgact tggatatgaa
    16261 tggtcatgtc aataacagta aatacttgga ctggattttt gaggtcatgg gagcggattt
    16321 tttgacccac tatattccca agaaaatcaa cctcaagtat gtcaaggaag ttcgaccagg
    16381 tggggtgatt acatcggctg ttgaacggac tggactggaa agcaagcatg aaattacaag
    16441 tgatggggtt atcaatgccc aagcaatcat tacttggcaa gaaataaaaa aggtttaggg
    16501 agaaatagat gaaatataaa ggctatttaa tcgatttaga cggaaccatt tataagggga
    16561 aagaccgaat ccctgctgga gagacttttg ttcatgaatt gcaaaagcgg gacattccct
    16621 atctctttgt aaccaacaat acaacccgca ctccagagag tgttaaggag atgttggctc
    16681 agaattttaa tatcgatacg cctctatcga ctgtctacac agcgactttg gcaaccatcg
    16741 actatatgaa tgatttgggg cttgaaaaga ccgtctatgt cgtcggagaa gcaggactca
    16801 aggaagccat caaggcggct ggttatgtgg aagacaagga aaaccctgcc tacgtggtag
    16861 ttggtctgga ttggcaagtc gactatgaaa aatttgccac agcaactctt gctattcaaa
    16921 agggtgccca ttttatcgga accaatcctg acctcaacat cccgacggaa cgtggtcttt
    16981 tgccaggtgc tggctcactg attacgctgc ttgaagtagc gacacgagtg aagccggttt
    17041 atatcggaaa accaaatgcc atcattatgg acaaggcggt tgagcactta ggtttggaac
    17101 gtgaagagtt aatcatggtt ggggacaatt atttgactga tatccgggct gggattgaca
    17161 atggcattcc aacactcttg gtgacgacag gttttaccaa ggcagaagaa gtagctggcc
    17221 tgccaatcgc accgacacat gtggtttcta gccttgcgga gtgggatttt gatgaaaact
    17281 aaattgacct tttggggctc tatgctcttt ctcctctccc tctcaatcct tctgaccatt
    17341 tatctggctt ggattttcta tcctatggag attcagtggc taaacttaac gaatcgagtc
    17401 tatctaaaac cagaaaccat tcaatacaat tttcatatct tgatgaatta tctgaccaat
    17461 ccttttagtc aggtcttaca gatgcctgat tttcgttcgt cagcagctgg tctgcaccat
    17521 ttcgcagtgg tcaagaatct ctttcatttg gttcagctag tagctctagt gacactgcca
    17581 agtttctatg tctttgtcaa taggattgtg aaaaaggact ttttgtctct ttatcgaaaa
    17641 agtctcctga ctctagtagt cttacctgtg atgattggac ttgggggagt tttgattggt
    17701 tttgaccaat tctttactct tttccatcaa attctctttg tgggagatga tacctggctt
    17761 tttgatccag ccaaggatcc tgttattatg attttgccag agaccttctt tcttcatgcc
    17821 ttcctcctct tttttgccct ctatgaaagc ttctttgggt atctgtgtct gaaaagtcgt
    17881 aggaagtgaa atgaaagatg tttttaattt gcatatataa aaatatatat cgtttaaaac
    17941 catcgttaag agtgaattaa ccaaatccaa ttgtgtcaat cgttcgcaaa cagcctattt
    18001 ttcttgaaaa aataggcttt ttttctaaaa atccctagtc aagcgcctta tttttttgta
    18061 taatagaagt agcaaagtat agataagaag agaaaagcat gattacacta tttctatcac
    18121 cgagctgtac atcatgtcgt aaggctaagg cctggttaga aaaacataag gttccctttg
    18181 tggaacacaa tattatgacc agtcctttaa caagaaaaga attgcaacac atcctttcct
    18241 tgaccgaaaa tggtactgat gacatcattt caactcgttc aaaaattttt caaaaattga
    18301 atattgatgt agagagtatt tcggtatcgg aattgcttca tttgattgag cagtatccta
    18361 gtcttttgcg tcgtccaatt attattgatg ccaagcgtat gcaaatcggt tttaatgaag
    18421 atgagattcg tgcttttctc cctcgtagtt atcgtaagca agaactaaaa gaagcaagaa
    18481 tgagagctgg tattagttaa tgaacaaaca gtatagttac ccactagatt tgtcgtggag
    18541 cactgaagaa cttgcttcag tgctttcttt ttttaatgat gttgaagctg cctatgaagg
    18601 caaagtagag gctaaaaagt tactggactc ctataaggga ttcaaagcgg tcgtgccaag
    18661 caagagcgaa gagaaacgtt tgggacgaga atttgaaacg gttagtggct attcacttta
    18721 ccgagcagtt caggctgcca aagaaaaagg ggaaggaaag atttctcttg gaaagtaaat
    18781 ttgaatttgc taaagagctt gttaagaaag caggccagta cattcttgac catatgcagg
    18841 aagacttgcg tgttgaaacc aagtcctctt caacagattt ggtgaccaga ctggacaaag
    18901 aagttcagga actcttggtt ggtgagattt tgtcccgtta tcctgaggat aagatttgtg
    18961 ctgaagaagg ttgtctgcga gcctcggttc aagagggcaa ggtttgggtc attgatccca
    19021 ttgatggtac caataatttt gtagcccagc aggaagattt tgctgttatg atggcttatt
    19081 ttgaaaatgg tcagggacag tttggtctga tttatgatgt ggtcaaaggg gattgttacc
    19141 acggtggtgg ggaatttcca gtttgtctaa atgataggcc cctagctcct tttaaaacta
    19201 aaccacttgg agattttctc attgcaggga atagtggtat gctggaaacc aatgaatggg
    19261 ggctggctga tttgagccga tcggttcttg gtgttcgtgt ctatggaagt gcggccatta
    19321 gttttgccaa gattttgtca gggcgtttgt tgacctatct cacttatctg caaccatggg
    19381 attatgccgc agctagtatt ttaggggaaa gtctgggcta tcgggttgtg accctttttg
    19441 gtgaagctcc tgattttcaa accagacagc cggtcatgat ggtgcctctt gagatgcagg
    19501 aggaaattca gtcctatatt tacgaaagga aaagaactta aatgcaattt ccagaaggat
    19561 ttgttgaaaa atataaagag atactaggag atgaggcaag agattttctt gcctcttttg
    19621 aggaggaagc ggtttcggcc tttcgggtca atcccttaaa agaagagcaa ctttcctttt
    19681 ctgatgccat tactcaaacc ccttggggcc actatgggaa ggtttcaggg aaatcgcctg
    19741 agcatgctac aggtttagtt tattcgcaag aacctgctgc tcaaatggtg gctcaagtag
    19801 cccaacccag tcctggtatg aaggtcttgg acttggctgc tgcaccgggg ggcaaatcaa
    19861 ctcaactggc agcctatcta gcaggtgagg ggctacttgt ttccaatgaa atttcaagca
    19921 aacgggctaa gattttggtt gaaaacatgg agcgttttgg agcgacaaat gtcgtggtga
    19981 ccaatgaatc tgccgaccgc ttggtcaagg tctttaaagg ctattttgac ttaatcgttc
    20041 ttgatgcccc ttgctctggt gaaggaatgt ttcgtaagca acctgatgct atggactatt
    20101 ggagcttaga ttatccgagt caatgtgcta gcttgcaaag agaaattctg gaggatgcag
    20161 tgaccatgtt agctgaaggt ggtcgtctgg tttattcgac ctgtacctgg gcacccgagg
    20221 aaaacgaaga gattgtcaat tggttgctgg aagagtatga ttttgacttg ttgccagtag
    20281 agcatatcaa tggaatggta gctggtattg acctgccaga aacggctcgg atgtaccctc
    20341 atcagtttaa gggagagggt cagtttgttg cccatctaca gtttaagggt aacaatccag
    20401 ctcctaaatt taaggcaagt aagagtaacc tcagccgtga acaagttgcc ttgtggcagg
    20461 aatttgccca aaaccatttg aaggtcaatc taccgggtat cttgcagact tttggagacc
    20521 agctttatct cttgccagaa cttttgccag atttagggaa gctcaagatt gctcgcaatg
    20581 gactgcatct gggcactttt aagaagaaac gctttgagcc cagtttcgct cttggtttag
    20641 ccttgaaacc gagtcaggtc gaacagtcgg ttgaaattgg ccaagaagcg tttgtcaagt
    20701 atgcggctgg agaaaccgtt cagctggcag aaagtctgcc aaatggttgg taccaagttt
    20761 tggttaaagg caatggcttg ggctttgcaa aggttactgg aaatgttttg aaaaattatt
    20821 ttccaaaagg cctcagattc aaatgaaaat gctagtcaaa tatcttattc tatgttatag
    20881 tgaaagtatg gattttttta gtaggatgat tcttgatatc ttgattgcca tcacatgtag
    20941 ttttactact cgatgaaaat caaagagcaa actaggaagc tagccataga tagctcaaaa
    21001 cactggtttg aagagatttt caaagagtac aagaagttta gttattagcg ttcttaccgc
    21061 ttgtaaacta gatttctcat aaaatagaat cttttccttt tagttgtaaa ctagtctggg
    21121 agagtagaga ggtttgagat acctttctag cttttggatt atcatctgag gagagtaatt
    21181 tcccttgcat taaaaagggg aaaaagagac acgaaatgat tataatgggt gacaatgggg
    21241 gaagggatag acaagagatt ttatccacat atgaaaaaag gaggttagga aagagtaata
    21301 tagcctatat tatataaata atcaattgcg cagaaatttg gtaagaattc atgcgtcaac
    21361 tcataaagaa ctacttaaaa aattcacagt attcataatt attttcgagg agaaaaacag
    21421 tgaaaaaaag aaaaaagctt gctctgtctc ttatcgcttt ttggctgacg gcttgtttag
    21481 taggctgtgc tagctggatt gatcgtggag aatccataac ggctgttggc tcaactgcct
    21541 tgcaaccctt ggttgaagta gcggcagatg aatttggcac gatccatgtt ggaaaaacgg
    21601 tcaatgtcca agggggaggt tctggtacag gcttgtccca ggttcagtct ggggcagttg
    21661 atataggaaa ctcagatgta tttgctgagg aaaaagacgg aattgatgct tctgctcttg
    21721 ttgaccacaa ggtcgcggta gctggcttgg ctctgattgt caataaggag gttgatgttg
    21781 ataacctaac gacagagcaa cttcgtcaaa tcttcatagg tgaggtaacc aattggaaag
    21841 aggttggtgg taaggactta cccatctctg ttatcaatcg ggcagccggc tctggttctc
    21901 gtgctacctt tgatactgtc attatggaag gtcagtctgc catgcaaagt caggagcagg
    21961 attcaaatgg agcggtaaaa tcaatcgtat caaaaagtcc aggagctatc tcttatttat
    22021 ctcttaccta tatagatgat tcggtcaaaa gcatgaagtt gaatggctat gacttaagtc
    22081 cagaaaatat aagtagcaat aattggccct tgtggtctta tgagcatatg tatacattgg
    22141 ggcagcccaa tgagttggct gcagaatttc tcaattttgt tctctcggat gagacccaag
    22201 aagggattgt caaaggattg aagtatattc cgattaagga aatgaaggtt gaaaaagatg
    22261 ctgccggaac tgtgacagtg ttggaaggga gacaataatg aatcaagaag aattagctaa
    22321 gaaaatgttg cttccatcaa agaattctcg tctggagaaa ttaggaaaag gtttgacctt
    22381 tgcctgtctt tctttgatag tcatccttgt ggccatgatt ttggttttcg tagcgcaaaa
    22441 aggcttgtcg accttctttg tcaatggtgt gaatatcttt gactttcttt tgggaggaac
    22501 ttggaatcct tctagtaaag aatttggtgc ccttcctatg attttgggtt cctttatcgt
    22561 taccattctc tcagccctta tcgcaacacc ctttgctatt ggtgcagcag tttttatgac
    22621 cgaagtatca ccaaaagggg cgaagatttt gcaaccagct attgaactcc tggttgggat
    22681 tccttcagta gtgtatggat ttattggctt gcaagtcgtc gttccctttg ttcgcagtgt
    22741 ctttggtggg actggttttg ggattttgtc agggatttcc gtcctctttg tcatgatttt
    22801 gccgaccgta acctttatga caacggatag cttgcgtgcg gttcctcgtt attatcgtga
    22861 agccagtttc gctatgggag ccactcgctg gcagactatc tggcgtgtga tcttgaaggc
    22921 ggcccgttct ggtattttca ctgcagtggt ctttgggatg gcgcgtgcct ttggtgaggc
    22981 tttagctatc cagatggttg tcggaaactc agctgttatc ccaacttcct tgaccacacc
    23041 agctgcaact ttaacttcta tattaactat gggaattggg aacactgtca tgggaactgt
    23101 aaataataat gttctctggt cactggcctt ggtactgctc ttgatgagtt tagtttttaa
    23161 cagtgtgatt aaattgatta cgaaagaaag aggaaagaaa aattatgcgc gctaagaaat
    23221 tagataaact tgcaacagct gtcctctata cgattgctag catcattgtg acaatcttgg
    23281 cttccttgat tctctatatc ttggttcggg gcttgcccca tatctcttgg tctttcttga
    23341 ctggaaggtc ttctgctttt caagcaggtg gtgggattgg cattcagctt tacaattcct
    23401 ttttcctatt ggtcattacc ttgattattt ctgtacctct ttctatggga gctgggattt
    23461 acttggctga atatgctaaa aaaggtcctg ttaccaactt tgtgcggact tgtattgaaa
    23521 tcttgtcctc tttaccatca gtggtggtgg gtctctttgg ttacttgatc tttgtagtcc
    23581 agtttgagta tggattttca atcatttcag gtgccttggc cttgacagtc tttaacttgc
    23641 ctcagatgac gcgtaatgta gaggatagtt tgaaacacgt tcaccatacc caacgtgagg
    23701 ctggtctggc tcttgggatt tctcgctggg agacagtggt tcatgttgtt attccagaag
    23761 cgcttccagg tattgtaacg ggtgtcgtct tggcatctgg tcgtatcttt ggcgaagctg
    23821 cagctctgat ctatacagca gggcaatcgg cgccagctct tgactggtct aactggaata
    23881 tcctcagtgt gactagcccc atctctatct tccgtcaagc agaaaccttg gctgtccata
    23941 tctggaaagt caatagtgaa ggcactattc cagatggaac cattgtatca gcaggttctg
    24001 ccgctgtgct cctgatcttt atcctgattt ttaactttgg agctcgtaag ttcggaagct
    24061 atctacacaa gaaattaacc gctgcctaaa ggagaagcca tgtcaacata taactgggat
    24121 gagaagcata tccttacctt tcctgaagaa aaagtagccc tttctactaa ggatgtccat
    24181 gtttactatg gtaaaaatga atccattaag gggattgata tgcaatttga aagaaataaa
    24241 attacagctt tgattggtcc gtcgggatcg gggaaatcta cctacttacg cagtctcaat
    24301 cgcatgaatg ataccattga tattgctaaa gtaactgggc agattctcta tcgtggaatt
    24361 gatgtcaacc gtccagaaat caacgtttat gaaatgcgta aacacattgg aatggttttt
    24421 caacgcccca atccatttgc taagtcaatt taccgtaata ttacctttgc gcatgaacgt
    24481 gctggagtta aggataagca agtcctagat gaaatcgtag aaacctccct tcgtcaggct
    24541 gccctctggg atcaggttaa agacgatctc cacaagtcag ccttgacctt atcaggtggt
    24601 cagcaacaac gtctctgtat cgctcgtgcc atctctgtta agccagatat cctcttaatg
    24661 gatgagccag cttcagcctt ggatccgatt gcgaccatgc aactagaaga gaccatgttt
    24721 gagctcaaga aagactttac catcatcatt gtaacgcata atatgcagca ggctgctcgt
    24781 gcaagtgact atacaggctt cttttacttg ggtgatttga ttgagtatga caagactgca
    24841 actattttcc aaaatgccaa gctacagtcc accaatgact atgtatctgg tcactttggt
    24901 tagaaaggaa accgtatgac agatgcgatt ttacaggtat cagacctgtc cgtttattat
    24961 aataaaaaga aggctttgaa tagtgtttcc ctatctttcc aacctaagga aattacagcc
    25021 ttgattggtc catctggatc agggaagtca accctcctca agtctctcaa ccgcatggga
    25081 gatctcaatc cagaggtgac cacaactgga tccgtggtgt acaatggtca caacatctac
    25141 agtccgcgta cagatacggt tgaattacgt aaggaaatcg gaatggtttt ccaacaacct
    25201 aatcctttcc ctatgactat ctatgagaat gttgtctacg ggcttcgtat caatggaatt
    25261 aaggataagc aggttctgga tgaagccgta gaaaaagcct tgcaaggtgc ctctatctgg
    25321 gatgaggtca aggatcgtct atatgattca gctattggat tgtcaggtgg tcaacagcag
    25381 cgtgtctgcg tggcccgtgt cttggcaact agtcctaaaa tcatcctctt ggatgagcca
    25441 acttcggctt tggatccgat ttcagctggt aaaattgagg aaaccttgta tggtctaaaa
    25501 gacaagtaca ccatgcttct ggtaacccgt tccatgcagc aagcttcacg tatctctgat
    25561 aagacaggat ttttcctaga tggagatttg attgaattta atgataccaa gcagatgttc
    25621 cttgatcccc aacacaagga aacggaagac tatattacag gaaaatttgg ataaggagat
    25681 gaaagatgtt acgatctcaa tttgaagaag atttagagaa attacataac cagttctacg
    25741 ctatgggaca agaagtgctc tcacaaatca atcgtacggt acgtgctttt gtcacgcatg
    25801 accgtgacct ggcaaaagag gtcatcgaag atgatgcaga agtaaatgaa tacgaagtga
    25861 aactggaaaa gaaatcattt gaaatgatcg cactccaaca accagtctct caagatttgc
    25921 gtacagtctt gactgtcctt aaggctgtat cagatgtgga gcgtatgggg gatcacgctg
    25981 tagccattgc ccaggcaacc atccgtatga agggggaaga acgcatccca gctgtagagg
    26041 aagaaattaa aaaaatggga cgtgaagtta aaagcgttgt tgaagcagca cttgatcttt
    26101 atcttaatgg ttctgttgac gacgcatacc gggtggcctc catggatgag caaattaacc
    26161 actattttga aactatccgt gaccttgcga ctgaagagat taagaaaaat ccagaagcca
    26221 ttgttacggg tcgtgattat ttccaagtta tttcctactt ggagcgtatc ggtgactatg
    26281 ctaaaaatat ctgtgaatgg gttgtctact ttgaaacagg taagattgtc gaactataaa
    26341 atagtttaat tctgtataaa aaggagcttg aaatcaactg atggctcctt tttttgaacg
    26401 aaaacatatt tttgagataa aaatttaaaa aacacttgac aagtaacttg gatatcgtta
    26461 taattataca aaattaacag agaggttgtt tatttatgaa atcaaaaaaa tggatatttg
    26521 ttttatgtaa ttttcttgca agtttcttct tagtagcttg ccagtcaggt tctaatggtt
    26581 ctcagtcagc tgttgaggcc attaagcaaa aggggaaatt agttgtggca accagtcctg
    26641 actatgcacc ctttgaattt caatcattgg ttgatggaaa gaaccaggta gtcggtgcag
    26701 acatcgacat ggctcaggct atcgctgatg aacttggggt taagttggaa atctcaagca
    26761 tgagttttga caatgttttg accagtcttc aaactggtaa ggctgaccta gcagttgcag
    26821 gaattagtgc tactgacgag agaaaagaag tctttgattt ttcaatccca tactatgaaa
    26881 acaagattag tttcttggtt cgtaaggctg atgtggaaaa atacaaggat ttaactagcc
    26941 tagaaagtgc taatattgca gcccaaaaag ggactgttcc agaatcaatg gtcaaggaac
    27001 aattgccaaa agctcaatta acttccctaa ctaatatggg tgaagcagtc aatgaattgc
    27061 aggctggaaa agtagatgct gttcatatgg atgagcctgt tgcacttagt tatgctgcta
    27121 aaaacgctgg cttagctgtc gcaactgtca gcttgaagat gaaggacggc gacgccaatg
    27181 ccgttgctct tagaaaaaat agtgatgatt tgaaagaagt ggtagacaag gtcatccaaa
    27241 aacttaagaa tgaaggaact taccaaagct atcttgaaaa agcagcaagt ctaactgaag
    27301 ttgaagaata agaaaaagca gagttggatg tcattccaat tctgctttta aatagtttaa
    27361 aacattttcc agattgtcta gggacacctt ggcaaattga taaggacagg tgcttaaata
    27421 ggcctcttca aagaagtcca agcccagttg actgtgtttg agactggcga ttttaggata
    27481 ctgtctcagg tctagcaata aaccatcgtg taggggataa tgaggaaggg gacaaggtgt
    27541 tttagttatc ctttcctcga tttgtttttg gtaagattca tgattggtca agcgagccaa
    27601 acgatttttt tcaaacaatt gactgtcaat atagagtgac agggcctttt gcataatgag
    27661 gttgctgtcg tagtctagga tatttttgta ggccacaaat gcttctttga tagcatttgg
    27721 aagaatgagt gctgtaatac gaagggcagg aaaaaggctg gtcgagaagg acttgatata
    27781 aatgacatgc tcctctgtat caagatagtg gaaggtttgg cccttcttgg agtccaaatc
    27841 acccagataa tcgtcctcta cgatatagac atcatacttg gcagctaagt taagaataga
    27901 tcgtttgtct tgctcagaat aggaatgtcc cagaggatag tgaaatctag gaatggtgta
    27961 gaaaaattta atttttcctg ttttgaagtg gccttccagc tcctccaagt caatcccatc
    28021 aatgcctcgt tcaatcgttt gatagtccag cccctgtgca atcaagaggc gattcatccg
    28081 atggtaggtt ggctgttcca ccaagatttc cttggcttgt ctaggaaagg atatttgaga
    28141 gaggataaac aaggcttgtt gggttccaga agtcagtact agttggttag ccttgcagta
    28201 gagagcttgc tcaaatagga gtttgtgaat ggactgtctt aggtcttcta atccttcttg
    28261 attgtcatag tagttgaaga ggtagttttc tcgtccaatc aaggtttcat tgacacagag
    28321 tcggaaatcg tcataggcac tggcatgttc gtcggtaacc tcgatttcta ggtcttgatg
    28381 ttgcccttgt tctaatacat agtagccact ctgaggcttg gcatagaggt attgttcgtg
    28441 ccgtaattcc agcagggctc gttgaatggt gtccttgctg cagtgaaagt caaggctcag
    28501 ttgacggata gaaggcaggc gactacccgt cggaaatcgt tcagactcga taccattttt
    28561 cagataggaa acgacctctt tgtacttgct ttgtttcttc attccagacc tcccttgatt
    28621 ttgttacatt gtaccctttt ttttccttct tggcaatgtc tagagcgttt ctctcgttca
    28681 catctagggg caaatgtggt atacttagga gtaagattta tagaataaca gacaagaaag
    28741 tgaatggata agaacgtgca ggaaccagtg aaattatttc aatacaatac tcttggagcc
    28801 ttgatggctg gcctttatgg tggtactatg acagtaggag aattgctaga acatggtgac
    28861 cttggtttgg gaaccttgga ttccattgat ggggaattga ttgtcttgga tggcaaggct
    28921 tatcaggcca aagggtcagg agaccagcca gaaattgtgg aagtgtcacc agatgccctt
    28981 attccttacg ctgcagtggt accgcatcag gcagaggtca ttttccgcca gcgctttgag
    29041 atgacagaca aggaattgaa agaacgaatt gagtcttatt atgatgggga aaatcttttc
    29101 cgctctatca agattcgggg ggaattttca catatgcatg tgcgtatgat tcctaagtca
    29161 acacccgata ccaagtttgc tgatgtcgca acccatcaac cggaatatag tcgtgacaat
    29221 gttgcgggga ctattgttgg tttctggacg cctgagattt tccatggggt cagtgtggca
    29281 ggctaccatc tgcacttcat atcagatgat ttgaccttcg gtggacatgt catggatttt
    29341 gtcatcaagg aaggcattat cgaggtggga gcagttgacc agttggacca acgtttccca
    29401 gtccaagacc gtcaatactt gtttgctaag ttcaatgttg acgagatgaa aaaagatatt
    29461 gaaaaggcag aataggagaa gaaaatgacc attcatatca ttattaccat gttgctgttg
    29521 ctagcttttc tgataggaag catttggttt gccaaaaaga aataccagat taatctagct
    29581 gtcttgggct tgggtgcagt cgctttcttt gtctcttcgc agattttgga aaaactggtg
    29641 catatcttga ttttgcatcc tcaaaaagac ggtagtattg ccctcttgca agatcatccg
    29701 cttatctata ttatctatgg cctagccatg gcagcatttt ttgaggaaac ggctcgtctt
    29761 gttttcttca aatggttgga gaaaaagaga agtttggaaa aggcagatgc cttggcctat
    29821 ggcctagggc atggtggctt ggagttgatt tttctaggcc ttattagttt actcaatctt
    29881 tacatcgttc tttcggcagt tcaaactcag aatccacagg ttatgcaatt actgtctgaa
    29941 aatatgttaa aaaccattca gtcactttcg gtctggcaga tttatttgct tggttttgag
    30001 cgaatcttgg cgcttggttt ccaattactt ttgacagttt gggtttacca agctgttcgc
    30061 cagaagaaat ggatttatct cctagcagcc tatggcttgc atgccttctt tgatctggca
    30121 ccatctcttt tccaagtagg ctggttgaca aatccagtct tggttgaagt gattctagca
    30181 ctggagctcg ttctggtcgc ctatggaacc aaggaaatct tttgtaaaaa atcataaaaa
    30241 ggggggaacc tctttttctt atgcaaaatc caaacaaggt atttttatgg tcgtcaaatg
    30301 tctctaaaaa tggtataatg gaatgaattt tgtaaaagga agagtgacat gtctgtaaga
    30361 gaaaaaatgc ttgaaatctt agaaggaatt gatatccgtt ttaaggaacc cttgcatagc
    30421 tatagttata caaaagtagg tggagaggct gattatttgg tctttccacg aaatcgtttt
    30481 gagttggctc gcgttgtgaa atttgccaac caagaaaata tcccttggat ggttcttggc
    30541 aatgcaagca atatcatcgt tcgtgatggt gggattcgtg gatttgtcat cttgtgtgac
    30601 aagctcaata acgtttctgt tgatggctat accattgaag cagaagctgg ggctaacttg
    30661 attgaaacaa ctcgcattgc cctccgtcat agtttaactg gctttgagtt tgcttgtggt
    30721 attccaggaa gcgttggcgg tgctgtcttt atgaatgcgg gtgcctatgg tggcgagatt
    30781 gctcacatct tgcagtcttg taaggtcttg accaaggatg gagaaatcga aaccctgtct
    30841 gctaaagact tggcttttgg ttaccgccat tcagctattc aggagtctgg tgcagttgtc
    30901 ttgtcagtta aatttgccct agctccagga acccatcagg ttatcaagca ggaaatggac
    30961 cgcttgacgc acctacgtga actcaagcaa cctttggaat acccatcttg tggctcggtc
    31021 tttaagcgtc cagtcgggca ttttgcaggt cagttaattt cagaagctgg cttgaaaggc
    31081 tatcgtatcg gtggcgtaga agtgtcagaa aagcatgcag gatttatgat caatgtcgca
    31141 gatggaacgg ccaaagacta cgaggacttg atccaatcgg ttatcgaaaa agtcaaggaa
    31201 cactcaggta ttacgcttga aagagaagtc cggatcttgg gtgaaagcct atcggtagcg
    31261 aagatgtatg caggtggttt tactccctgc aagaggtagt ggggacctga cagagccccg
    31321 atcggttaat ctatgaaaaa gaaggaattt atgccaattg aaaaaaccaa ttatcgaatt
    31381 caaaaacgtc tctaaagttt ttgaagacag caacaccaag gttctcaaag acatcaactt
    31441 tgagttggaa gaagggaaat tctacaccct tctaggtgca tctggttcgg ggaaatcaac
    31501 tatcctaaac attattgcag gtttactgga tgcgacgaca ggagatatca tgctagacgg
    31561 tgttcgtatc aatgatattc caaccaacaa gcgcgacgta cataccgtct tccaatccta
    31621 tgccttgttc ccacatatga atgtgtttga aaatgttgcc tttccacttc gcttgcgtaa
    31681 aattgataag aaagaaattg agcagcgtgt agcggaagtt ctcaagatgg ttcagttgga
    31741 aggttatgaa aaacgttcca tccgcaaact ttctggagga caacgtcagc gtgtggccat
    31801 cgcccgtgct atcatcaacc aaccccgtgt ggtcttgttg gacgagcctt tatcagcgct
    31861 ggacttgaaa ttgagaacag acatgcagta cgaattgcgt gaattacaac aacgattggg
    31921 cattaccttt gtctttgtca ctcacgatca ggaagaagct cttgccatga gtgactggat
    31981 tttcgttatg aatgatggcg agattgtcca gtctggaacc cctgtggaca tctacgatga
    32041 gccaatcaac cactttgttg ccacctttat cggggagtca aacatcttgc caggtaccat
    32101 gattgaggac tacttggtcg aatttaacgg caaacgcttt gaagcggttg atggtgggat
    32161 gaagccaaat gaacctgttg aggtcgttat tcgtccagag gacttgcgca ttacccttcc
    32221 tgaagaaggc aagctccaag ttaaggtcga tacccagctc ttccgtgggg tgcattatga
    32281 aattatcgcc tatgacgaac ttggaaatga atggatgatc cactcaaccc gtaaggccat
    32341 cgtgggtgag gaaatcggtc tggactttga accagaagac atccacatca tgcgtctcaa
    32401 tgaaaccgaa gaagagttcg atgctcgtat cgaagaatac gtggaaatcg aagagcaaga
    32461 agcaggtctg atcaatgcga tcgaggagga aagagatgaa gaaaacaagc tctaaactct
    32521 ttgtagtgcc ctacatgctt tggattgccc tctttgtatt ggcacccttg gtcttgattt
    32581 tcggacaatc ctttttcaac attgaaggcc agtttagttt agaaaattat aaatcttact
    32641 ttgcgtcaca aaacttgacc tacctcaaaa tgagtttcaa ctcagtgctt tatgcaggga
    32701 ttgtgacctt tgtaaccttg cttatcagct atccaacagc cctctttttg acccgtctca
    32761 agcaccgtca actctggctc atgctgatta tccttcctac ctggatcaat ttgctcctta
    32821 aagcctatgc ttttatcggg atttttggtc aaaatggctc tattaaccaa ttcttggaat
    32881 ttatcggaat tggttcacaa cagttgcttt ttaccgattt ttcctttatc tttgtcgcaa
    32941 gctacatcga gctccccttt atgattttgc cgattttcaa tgtcttagac gatatggata
    33001 ataatctcat caatgctagt tacgaccttg gtgcaactaa gtgggagacc ttccgtcatg
    33061 tcatcttccc tctatctatg aacggtgtgc gaagtggggt tcagtcggtc tttatcccaa
    33121 gtttgagtct cttcatgctg acccgtttga ttggtgggaa ccgcgttatc accttgggga
    33181 cggctattga gcagaatttt ctaaccaatg acaactatgg tatgggttca actatcggtg
    33241 tgattctcat cctgaccatg ttcatcacca tgtgggtgac taaggaaagg agagaacgat
    33301 gaaaaaattt gccaaccttt atctgggact ggtctttctg gtcctctacc tgcctatctt
    33361 ttacttgatt ggctatgcct ttaatgctgg tgatgatatg aatagcttta caggttttag
    33421 ctggactcac tttgaaacca tgtttggaga tgggagactc atgctgattt tggctcagac
    33481 atttttcttg gccttcctat cagccttgat agcgaccatt atcgggactt ttggtgccat
    33541 ttacatctac cagtctcgta agaaatacca agaagccttt ctatcactca ataatatcct
    33601 catggttgcg cctgacgtta tgattggtgc tagcttcttg attctcttta cccaactcaa
    33661 gttttcactt ggctttttga ccgttctatc tagtcatgtg gccttctcca ttcctatcgt
    33721 ggtcttgatg gtcttgcctc gactcaagga aatgaatggc gacatgattc atgcggccta
    33781 tgacttggga gctagtcaat ttcagatgtt taaggaaatc atgcttcctt acctgactcc
    33841 gtctatcatt gctggttatt tcatggcctt cacctattcg ttagatgact ttgccgtgac
    33901 cttctttgta acaggaaatg gcttttcaac cctatcagtc gagatttact ctcgtgctcg
    33961 caaggggatt tcgctagaaa tcaatgccct ttctgctcta gtctttctct ttagtattat
    34021 cctagttgta ggttattact ttatctctcg tgagaaggag gagcaagcat gaaaaaaatc
    34081 tattcatttt tagcaggaat tgcagcgatt atccttgtct tgtggggaat tgcgactcat
    34141 ttagatagta aaatcaatag tcgagatagt caaaaattgg ttatctataa ctggggagac
    34201 tatatcgatc ctgaactctt gactcagttt acagaagaaa caggaattca agttcagtac
    34261 gaggcttttg actccaacga agccatgtac actaagataa agcagggtgg aacgacctac
    34321 gatattgcca ttccaagtga atacatgatt aacaagatga aggacgaaga cctcttggtt
    34381 ccgcttgatt attcaaaaat tgaaggaatc gaaaatatcg gaccagagtt tctcaaccag
    34441 tcctttgacc caggtaataa attctccatc ccttacttct ggggaacctt aggaattgtc
    34501 tacaacgaaa ccatggtaga tgaagcgcct gagcattggg atgacctttg gaagctggag
    34561 tataagaatt ctatcatgct ttttgatggg gcgcgtgagg tgctgggact aggactcaat
    34621 tccctcggct acagcctcaa ctccaaggat ccgcagcagt tggaagagac agtggataag
    34681 ctctacaaac tgactccaaa tatcaaggct atcgttgcgg acgagatgaa gggctacatg
    34741 attcagaata atgttgcaat cggcgtgacc ttctctggtg aagccagcca aatgttagaa
    34801 aaaaatgaaa atctacgtta tgtggtaccg acagaggcca gcaatctttg gtttgacaat
    34861 atggtcattc ccaaaacagt taaaaatcaa gactcagcct atgcctttat caactttatg
    34921 ttgaaacctg aaaatgctct ccaaaatgcg gagtatgtcg gctattcaac accaaaccta
    34981 ccagcgaagg aattgctccc agaggaaaca aaggaagata aggccttcta tcccgatgtt
    35041 gaaaccatga aacacctaga agtttatgag aaatttgacc ataaatggac agggaaatat
    35101 agcgacctct tcctacagtt taaaatgtat cggaagtagg agataaacgt aagaagacga
    35161 atcagtcaag ctggttcgtt tttaaggaat agaagtcagt ttttagagcc ctatcttttt
    35221 ctattctagt tgtttatttg tttatttgct tatttgcttg cctagtagta tactaagcct
    35281 atactcttca aaccacgtca gcgttgcctt gccgtactca agtacagctt gaagctagct
    35341 tcctagtttg ctttttgatt tttattgagt attaacctta cagaaagcgg caacaaataa
    35401 tgaaaatgtc tacttttttc aaaaaaagtt tctggccaac ctttatgatt gttaaccaaa
    35461 ctgctatact attccattta aatgatggct tggatcgaca atacctaaca actgagtcca
    35521 tatattgggt gataggcacc tttatatttg gaaatattct agtagctgtg tttagtaata
    35581 tgaaaatttg ggataaaaag aaaaatggca gtaagaaaaa atatatcctg aaaaagtaat
    35641 cagagatgta gggaattggt ctaattcaac ggagatcatt tccagttgac gcaagcttaa
    35701 aaaaacgtta taataagaaa gttgagaatt gattttcact tgtcttagtc cagagaaatg
    35761 gcggtgctgc gagccatcta agctaggaag tcatgctact caatcataca attgcataag
    35821 aacaagagaa tgacaagttc attgaatgaa ggtggtaccg cggtttttcg cccttcgtga
    35881 tatgagcttg tcttttgatt tttggaggtg ttgatgaaaa catttcttgt caaacaaaag
    35941 tttcgtcttg gaggcgaacg cttcgctatc aaggatgaca ggggagaaat tgcctatcag
    36001 gtggagggat cattttttaa gattcccaaa acttttacca tctatgatgc ggctggtgaa
    36061 caagtcagtc agatcagtaa agaaatcttg accttgcttc ctcgttttga gattcagctt
    36121 cgggatggct cgagttttgt cattcgtaag aagttgacct tctggcgaga taagtatgag
    36181 tttgataatc taggtcttcg tatcgagggc aatatctggg atttgaattt caaattgctg
    36241 gatgatcgcg atcagttgat tgcggaaatt aagaaggaac tcttccatct gacctctacc
    36301 tataccgtaa cggttcttga agacgcttat gcagacctag tcatttccct ctgtgtcgcg
    36361 attgactatg tggaaatgct ggaaagccaa tcacattaaa caagtgaata aggagacaat
    36421 atgaaacaac tatctagtgc acaagtacgc caaatgtggc ttgatttctg ggcgaccaaa
    36481 ggtcactcag tagaaccatc agtaagtttg gttcctgtaa atgacccaac tcttttgtgg
    36541 atcaactctg gggtagcaac ccttaagaaa tactttgacg ggaccattat ccctgaaaat
    36601 ccacgtatta ccaatgccca aaaggctatc cgtaccaacg acatcgaaaa cgtagggaag
    36661 actgcgcgtc accataccat gtttgaaatg ctggggaact tctctatcgg ggattacttc
    36721 cgtgacgaag ctatcacttg ggcttatgag cttttgacaa gccctgaatg gtttgatttc
    36781 cctgctgaaa aactttacat gacctactat ccagacgata aagattctta caaccgctgg
    36841 attgaagtgg gagtggatcc aagtcacttg attccaattg aggacaactt ctgggaaatc
    36901 ggtgcgggac cttctggacc agatacagaa atcttctttg accgtgggga agcctttgac
    36961 ccagaaaata tcggtcttcg cctgcttgca gaagatattg aaaacgaccg ttatattgaa
    37021 atctggaaca tcgttttgtc acaatttaac gcagaccctg ctgttcctcg tagcgaatac
    37081 aaggaattgc cacataagaa cattgatacg ggcgctggtt tggagcgttt ggtggccgtt
    37141 atccaagggg ctaagaccaa ctttgaaacg gacctcttca tgccgattat ccgtgaagtc
    37201 gagaaattgt ctggtaaggt ttatgaccaa gatggcgaca acatgagctt caaggttatc
    37261 gcagaccaca ttcgttctct ttcatttgct atcggtgatg gtgcccttcc aggaaatgaa
    37321 ggtcgtggtt atgttcttcg tcgtcttctc cgtcgtgctt ctatgcatgg tcaaaaattg
    37381 ggtatcaacg agcctttcct ttacaaattg gttccaactg ttggaaaaat catggaaagc
    37441 tactacccag aagtgcttga gaaacgtgac tttattgaga aaatcgttaa gagcgaagaa
    37501 gaatcatttg cccgtaccct tcactcaggt caacactttg cccaaggcat tgtggcagac
    37561 ttgaaagaaa aaggtcaatc tgtcattgct ggtcaagatg tctttaaact ctatgatact
    37621 tatgggttcc cagttgaatt gactgaagaa atcgctgaag aagctggtat gactgtagac
    37681 cgtgaaggtt ttgaagcagc catgaaagaa cagcaagaac gcgcgcgtgc gtcagctgtc
    37741 aagggtggct caatgggtat gcaaaatgaa actcttcaaa acatcactgt agaaagtgtc
    37801 ttcaactaca atactagcca attgtcttct aaattggtag ctatcgttgc tgacaatgca
    37861 gaagtaggag ctgtttcaga aggaactgcc tctcttatct ttgcggaaac gtcattttat
    37921 gctgaaatgg gtggacaggt agctgactac ggacaaatct tggatgagtc aggtaagatt
    37981 gtggctactg tgaccaatgt tcagaaagcc ccaaatggtc aagcccttca tacagttgaa
    38041 gtccttgcac cgcttgcctt gaaccaagaa tataccttgg caattgatag caatcgccgt
    38101 caccgtgtca tgaaaaacca cactgcgact catttgcttc acgctgccct tcacaatatc
    38161 cttggaaacc acgcaacaca ggcaggatct cttaacgaag ttgaattcct tcgctttgac
    38221 tttacccact tccaagcagt aactgctgag gaacttcgtg cgattgaaca gcaagttaac
    38281 gagaaaattt gggaagcact tgaagtgaag acagttgaaa cggatattga cactgctaaa
    38341 gaaatgggag ctatggccct ctttggtgag aaatacggca aggaagttcg tgtcgtgact
    38401 atcggtgact actctattga actttgtggt ggtactcatg ttgacaacac ttctgagatt
    38461 ggtctcttca aaattgtcaa agaagaagga atcggttcag gaactcgccg tatcttggca
    38521 gtgactggta aggaagcctt tgaagcctat cgtgaacaag aggatgctct taaagctatc
    38581 gcagcaacct tgaaagcacc tcaagtcaag gaagtacctc acaaggtaga aggacttcaa
    38641 gaacaacttc gtcaacttca aaaagaaaat gctgagttga aagaaaaagc cgcagctgca
    38701 gccgcaggcg atatcttcaa agatgttaag gaagtcaacg gtcatcgtta cattgctagt
    38761 caagtgtctg tatccgatgc cggtgccctt cgtacttttg cagataactg gaaacaaaaa
    38821 gactactctg atcttcttgt cctagttgcc gctatcggtg acaaagtcaa tgtccttgta
    38881 gcaagcaaga caaaagacct tcatgcagga aaccttgtca aagaattagc accaatcatc
    38941 gatggacgtg gtggtggtaa accagacatg gccatggcag gaggaagcaa ccaagctaag
    39001 atccaagaat tgttggatgc agtagcaggt aaattgtaat caagtaaaga tctatccatt
    39061 tgggtaggtc tttttgtgaa tacaaaaaag ccaaatccgc ttggacctag cttggttatt
    39121 atgagctatt agatggtatt gactgcccag acacttacgg atctagctga gacagggaat
    39181 tgtccataac cttcctcatc aattgtaact tgaccttggt ggttaccaag taaatctaca
    39241 aaggtttgat tagtccattc ttgaccgaca aacattgact tgctgttttc ttggtcattt
    39301 gagataagga ctgcgattgg ggattgattt tcagcacctg aacgtaccca accgatacag
    39361 ttagcatggt caaagtagtc attttgttct ccataggcca agtcttttcg gatggctagg
    39421 aggcggtcaa ggatttcttt gaaatcttct tgagcatact ggcctgaaat cccatagtag
    39481 tctccgtaaa agacacatgg aaggccgtct tggcgtaaca aaatgagggc ataggctgct
    39541 ggcttgaacc attcttcaac ggtagactca agggcttgtc ctcgttgggt atcgtggttg
    39601 tcgacaaaag tcacagcctt gtcaggcttg agttcaacca ggctatctgt gaaaatgcca
    39661 cgaaggtcat agtttgcgcc agcttgactg gcttcaaaga gattctggtg gagacgaaca
    39721 tcgacaaggt caaagtgttc ttccgttttt tcgagatagt ccagattggc ttccttgtct
    39781 gggttccaaa attcaccaaa aacatagaaa tcgtcaccgt atttttcctt catatcgcgg
    39841 atgaagttgc gcataaagaa agagtcaata tgcttaacgg catccaaacg gaaaccagct
    39901 acaccagtcg tttccatgaa ccaatcagcc cagtcataga tgttttggat gacttcagga
    39961 tgtttaaagt ctaggtcggc atacatgagg tagtcgtagt ttccgttttc gttatcgacc
    40021 aattccttgt tagcccagcc cttgttgtcc ccttggatca gataaatccc agatttactg
    40081 cgtttggcat cgtagtctgt accggtgaag tggtaccaat gccagtggaa gccattatag
    40141 gtatcttggc gaccatcgaa ggtaaaacta gtccagccat tgatggtgaa gggttctcca
    40201 agttcaactg tacggtctac aggatcaact tcgataacct gaaaggcttc cctgttatcg
    40261 gcagcagcct tgtggttgag aactacatcg gccataggtt gaattccctg ttctttaagg
    40321 gcttgaatgg cttgaagata gtcttctttg aaaccatact tggtgcggac agtccctttt
    40381 tggttgaact ctcctaagtc aaataagtca tagaccccat agccgacatc tttttcgttg
    40441 gttgccttga aggctggtgg catccagacg tgactgatcc ccagatgagc taggtgtgga
    40501 gcattttcag ccagacgcgt ccagtgttga ccgtcgtggg gcagatacca ttcaaagtat
    40561 tgcatgagtg tttgattttg catgatgttt cctcttactt gtcaatcttg ttctttattc
    40621 tatcataaag tatctctcgg cgcaaacgtt tgcgtaagat agaaggaaac tattttaact
    40681 acttaaaata aagtattgat ttttttgtat caaagtgcta gtatagcgat gtataataca
    40741 gataaagata ggagttgtcc catgattgaa tttcaaaatg ttagtaagtt gtatggtgat
    40801 aaagaggcct tgagtaatct caatttgcag attgaaaatg gagagattat gggcttgatt
    40861 ggtcataatg gggctggaaa atcgaccacc ataaaatccc tagtcagtat catttcaccc
    40921 agcagtggtc gtattttggt agacggtcag gagttatcgg aaaatcgctt ggcgatcaaa
    40981 cgaaagattg gctacgtagc agactcgcct gacttatttt tacgcttaac ggccaatgaa
    41041 ttttgggaat tgatcgcttc atcctatgat ctgactagct ctgacttgga gactagtcta
    41101 gctaggctat tgaacgtttt tgattttgct gaaaaccgct atcaggttat tgaaactctt
    41161 tctcacggaa tgcgtcagaa agtctttgtc attggggcac tcttgtctgc tcctgatatt
    41221 tgggttttgg acgaaccctt gactggtttg gatccccagg ccgcctttga tttgaagcaa
    41281 atgatgaagg aacatgcaca aaaaggcaag acggtcttgt tttcaactca tgtccttgag
    41341 gtagccgagc aagtctgtga tcggattgct attttgaaaa aggggcattt gatctattgt
    41401 ggtagtgtag agaacttgag gaaagaccac ccagaccagt ttttggaaag tatctacctt
    41461 agtcttgctg gtagaaaaga ggaggttgcg gatgcgtctc aaggtcatta aaaaattagt
    41521 tgatatcaat atcctctatt catctcaaga agctaatctg gctaatctac gaaagaagca
    41581 ggctaagaat cctgggaaaa aagtaaatgt ttctgctaga gtcctaagtt cttacatttt
    41641 ttccagtctc ttgatgctca tctgttttag taatatagcc attcattttc cttttgagga
    41701 aatgcctatt tattttagct cgatggttgc tattttactg gtgctggcct tttcaacttc
    41761 tttcactgcc ttttacaatg tcttttatga gagtaaggac ctggcctcct ataggcccta
    41821 tgcctttaaa gaatcagaga ttataatggc caaaggtctg tctgtcctct tgccagctct
    41881 aactggaatt gtaccaatcc tagcttattt tctagccctc tatattagtc tagctccttc
    41941 tctttggctg ggtttgcctt tgatgctact gtccttgacc ttattatttg tctctgttac
    42001 tttagtgacg gtagtggcag tacatttctt ggctcagact agggtcttca gaaagtatca
    42061 gtctattttt tcgaatgtga tgattgggat aggagttctc atacctttaa tatttatctt
    42121 ctttcttcag tcgacttttg gaagtattgt tgacaaagtt agagacattc catttctcct
    42181 ttatcctctt catatctttt acaaaatagc agtggagcct ttttcgacag aagccttagt
    42241 gggtctgctc gcttggatag gactaactct cttcctgctt tatctgacca aaaagaaggt
    42301 ccttcctcgt ttttatgacg tgatcctgct taacagtgag gagaaggtca aaaaagaacg
    42361 tcgcagcaag gagaggattt caactactaa aaagggcttt ttccgtatgg ttttacgcta
    42421 ccacctcacc ctcttgggac aggggactgg tgtgattaca gtgcttttta caagtgcttt
    42481 ccttccttat ctcatgatga tcagtctgat ttccaaaatc cgagattctc agatagttcc
    42541 agacattcat cctccatact ggttaccctt gttttttgta ggagtgttta tagcagttgt
    42601 caataacaat atcaccagcc tgcattcaat tgccttgtcc ttggagaggg aaaatgttga
    42661 ttttctgaag agtttaccct ttgactttgc tcgttatgtg aaagtgaaat tttggattat
    42721 ctttgctgtt cagtcctttt taccagttct gactttgctc ggtctttctc tatatctagg
    42781 cttgcccatc ctttcgatga tttaccttct tgtagtctgg atcattgcca gtgtcatcct
    42841 ttcttgccac cattacttta aggacgttaa aaatctgtca accaattgga gtagcattac
    42901 ggacctggtg aatcgttcaa atggcatagt cgccatagtt ttattgttta tttatagtgc
    42961 aatcctgatg gcccttgtaa ttgggagcat attcttggtt cagtctctct cccctatcct
    43021 tgccatcaac ttgggagtag gagctcttat cgtcttgctt gctcttgcta tttttggcta
    43081 tcattattac ctgtcacgca tattggcaga aatagaaaaa agatgagata gttggttgct
    43141 tgcttgataa attcaattcg acaaacgctt ttatagtttg ttagaatgta gttgtaaatg
    43201 attaagattg gtaatcaaaa atatagggag gaatgttttg aataagaaat ataatatagt
    43261 tctattattg ttgtttatag tttatttatt gggatatttt tcaatttcaa aaacgttaat
    43321 tcctataatg tgtgtgatcc aagtattttt gatagaacat atatttagag ttcgaaatag
    43381 aatgatgcaa ataggtgaaa ttttaattat tgttgcttct ataatattat ttattgatag
    43441 tatattgagt ttgtaacaaa aggcttttct ataaaatcaa attttccaga tacctattga
    43501 agcagattta tttcttcatc tttcttctac tacctttgtc actaaatttg acagacacat
    43561 attgctgatt caacctctct acctataatc tcacagttaa cctgaggcta gtttcatagt
    43621 ttgctatttg attttcgttg ataaaaagaa atgctcctcc aagatggaag agcatttttt
    43681 attgtgattc ttacacattt acttcctagt tttgcaggaa gtctagtata ccatttttta
    43741 aaagaagagt aaaaaagcaa gggtagtttc ttttttgaga attgtctaaa agtttgatat
    43801 aatggtagtt atgaatagaa taagagtcag caaaagggtt gaaaagaagc ttgctaaggg
    43861 gctagtttta ctagaagcca gtgatcttga gaatgtcaat cttaaggatc aggaagtaga
    43921 ggtgcagggt caggaaggaa actttcttgg gactgcctac ctttctcagc aaaacaaggg
    43981 cttgggctgg tttgtcagca aagacaaggt ggccttcaat caagctttct ttgaaacgtt
    44041 gtttagaaaa gccaaagaaa agagaaacgc ctactatcaa gatgatttga caactgcctt
    44101 tcgtctcttt aatcaagagg gagatggctt tgggggtctg acagtggacc tttatggcga
    44161 ctacgccgtc ttttcttggt ataactctta tgtttatcag attcgtcaga ctatatcaga
    44221 agcctttaga caggttttcc ctgaggtttt aggagcttat gagaaaatcc gctttaaggg
    44281 tttggactat gaatctgccc atgtttatgg tcaagaagca cctgactttt tcactgtttt
    44341 agaaaatggt gtcctgtatc aagtctttat gaatgatggc ttgatgacag gaattttcct
    44401 agaccagcat gaggttcgcg gtagtttagt tgacggcttg gctatgggta aatccttact
    44461 caatatgttt tcctacacag cggctttttc agtagctgcg gccatgggag gagctagcca
    44521 gacaacttct gttgatctag ccaaacgttc acgagaattg tctcaagcgc attttcaggc
    44581 aaatgggctc agcacagacg agcatcgttt tatagtcatg gatgtctttg agtatttcaa
    44641 atatgccaaa cgcaaagact tgacctacga tgtgattgtc ctagatccgc ctagctttgc
    44701 tcggaataaa aaacaaactt tctctgtggc caaggattat cacaagttga tttcccagag
    44761 tcttgagatt ttaaatccgg gagggattat cattgccagt accaatgctg ccaatgtttc
    44821 ccgtcagaaa tttacagaac aaattgataa aggttttgca ggaagaagtt accagatttt
    44881 aaacaaatat ggtcttccag cagattttgc ctataataaa aaagatgaaa gtagtaatta
    44941 cctcaaggtg attagtatga aggttagtaa atgaaattaa tcgtttcagt aatgccaaga
    45001 agtttagagg aggctcaggc tctggatgcc acgaggtact tggatgccga catcattgaa
    45061 tggcgtgccg actatctgcc taaagaagcg attttgcagg tagctccagc catttttgaa
    45121 aaattcgcag gccgtgagtt ggttttcacg ctacgaactc gctccgaagg tggagaaatc
    45181 gacctttctc cagaagagta tatccatcta atcaaggaag ttgcgcaact ctatcaacca
    45241 gactatattg attttgagta ctatagctac aaggatgttt ttgaggaaat gctggacttc
    45301 ccaaatcttg ttttgagtta ccataatttc caagaaacac ctgagaacat gatggaaatc
    45361 ttgtcagagt tgacgatcct aaatccaaaa cttgttaagg ttgcggtgat ggctcacacg
    45421 gagcaggatg tcttagactt gatgaactat acacgaggct ttaaaaccct caatcctgaa
    45481 caggaatatg tgaccatttc tatgggtaag gtgggcaagg tctctcgtat cactgcggat
    45541 gtgactggtt cgagttggtc ttttgccagt ctggatgagg ttagtgcccc tgggcagatt
    45601 tctctagcta gcatgaaaaa aatcagggag attttggatg aagcttgatg gctatacacg
    45661 tttagctgca gttgttgcca atcctattaa gcattctatt tctcccttca tccacaatag
    45721 agcctttgag gcgacagcta ccaacggtgc ttatgtggct tgggagattg aagcgagtga
    45781 cttggcagaa acagtggcca atattcgtcg ctaccagatg tttggcatca atctgtccat
    45841 gccctataag gagcaggtga ttccttattt ggatgagcta agcgatgaag cgcgcttgat
    45901 tggtgcggtt aatacggttg tcaatgagaa tggcaattta attggatata atacagatgg
    45961 caagggattt tttaagtgct tgccttcttt tacaatttca ggtaaaaaga tgaccctgct
    46021 gggtgcaggt ggtgcggcta aatcaatctt ggcacaggct attttggatg gcgtcagtca
    46081 gatttcggtc tttgttcgtt ccgtttctat ggaaaaaaca agaccttacc tagacaagtt
    46141 acaggagcag acaggcttta aagtggattt gtgtgcttta gaatatgttt ctgaactgca
    46201 agcaaggatt gccgagtcgg atttgctagt taatgccacc agtgtgggca tggatggcca
    46261 atcctctcct gttcctgaaa acatagtctt accagaaact cttttagttg cagatatcat
    46321 ataccaaccc tttgaaacac cgtttttgaa atgggctaga agtcagggca atccagcagt
    46381 caatggtctg ggaatgttgc tctatcaagc tgcagaagct tttcaactgt ggacaggcaa
    46441 ggaaatgccg acagaagaga tttggcagtc tttaacagaa aaataccaat aaagaaaggg
    46501 agactctcct atgaaaatca gaatcgatat tcctcatcat ccttatgata ttcagattga
    46561 aaaaggttgt atggcccagg ctggtcagtg gttgcgagaa ctctggcaac cgcaaaaggt
    46621 agtcattgtg acagataacc atgtagcctc tctctatgca gagaaggtca agctcagcct
    46681 agaagatgct ggttttcagg tagctgtttt tgatttctta gaaggtgaag aaagaaagaa
    46741 tttaactact gttcagaaag tctatgaatt tctagtcaag caaggtctga ctcgtagcga
    46801 tggaatcgtt gctcttggtg gtggcgttgt tggggacctg gctggctttg tagcctctac
    46861 ctatatgcgg ggtattcact ttgttcagat tccgactagt ttgacagctc aggttgattc
    46921 ttctatcggt ggaaagacag gcgttaacac accatttgct aaaaatatgg tggggacctt
    46981 tgcccaacca gatggggttc tgattgatcc acttgttctt gaaaccctcg gaaaaagaga
    47041 gttgattgaa gggatgggtg aagttatcaa gtatggcttg attgaggatc cagaactgtg
    47101 ggctctcttg acgggactga atggttctgt tgagagtatt ttggaacatg cagagacctt
    47161 gattgaacat tcttgtcagg tgaagcgcaa gatggtggtt gaagatgagt tggacaatgg
    47221 tattcgtctt tacctcaatt ttggccacac tattggccat gccatcgaag cgactgccgg
    47281 ttatggcaag gtcatgcatg gagaggctgt tgccatggga atggtacaga tttccaagat
    47341 tgctgaggaa aaaggcctca tgccagctgg cattacccaa tctatcacag agatgtgtca
    47401 gaaattcggc ttgcctgttg actatgaaaa ttgggaagtt gacaagcttt atcaggctct
    47461 tactcatgac aagaaagcgc gtggcaacac cttgaaattg gtcttggtgc cagagcttgg
    47521 ttcagcgatc attcacccag tttctctgga agagatgaaa gactacttgg taaaataagg
    47581 agagtgtatg agatatttaa ctgcaggaga atcacacggc ccccgtctaa cagctattat
    47641 tgatggaatt ccagctggac ttccattgac agctgaggat atcaatgagg accttagacg
    47701 ccgtcagggt ggctacggtc gtggtggtcg tatgaagatt gagaatgacc aggttgtctt
    47761 tacttcgggc gttcgccacg ggaagacgac aggggcgcct attactatgg atgtcatcaa
    47821 taaggaccac cagaaatggc tggacatcat gtctgcggag gacattgaag accgtcttaa
    47881 aagcaagcgg aaaattactc atcctcgccc aggtcatgcc gatttggttg gggggattaa
    47941 gtaccgtttt gatgatttgc gaaattcttt ggagcgttca tcagctcgtg aaaccaccat
    48001 gcgggtggca gttggtgcag tagccaaacg cctcttggct gagttggata tggagattgc
    48061 caaccatgtc gtggtctttg gtggcaagga aatcgatgtt cctgaaaatc tgacagtcgc
    48121 tgaaattaag caaagagctg cccagtctga agtttctatt gtcaaccaag aacgagaaca
    48181 ggaaatcaag gactatattg accaaatcaa acgtgatggt gataccatcg gtggggttgt
    48241 ggagacagtc gtcggaggcg ttccagttgg tcttggttcc tatgtccaat gggatagaaa
    48301 attggatgca agattggctc aagctgttgt ctctatcaat gcctttaaag gggtggaatt
    48361 tggtcttggc tttgaggctg gttatcgtaa aggcagccaa gttatggatg aaattctctg
    48421 gtctaaagaa gacggttata ctcgccgtac caataatcta ggtggttttg aaggtggtat
    48481 gactaatggg caacccatcg ttgttcgtgg ggtcatgaaa cccattccta ctctttataa
    48541 acctcttatg agtgtggata tcgaaaccca cgaaccttac aaggcaaccg tggagagaag
    48601 tgatccgact gctcttccag ctgcaggaat ggtcatggaa gcagttgtag caacggttct
    48661 ggcgcaagaa atcctcgaaa aattctcatc agataatctt gaggaactaa aagaagcggt
    48721 agccaaacac cgagactata caaagaacta ttaaggagtt cctatggcaa aaacaatcta
    48781 tatcgcaggt cttgggttga ttggagcctc tatggcactt ggtatcaaac gcgatcatcc
    48841 agattatgaa attttaggtt ataatcgtag tcaagcttcg agagatatcg ccttgaaaga
    48901 aggcatgatt gaccgtgcaa cggatgattt tgctagtttt gctcctttgg cagatgtcat
    48961 tatcctcagc ttgccaatca aacaaactat tgctttcatt aaggagttgg ccaatttgga
    49021 tttgcgagaa ggcgttatta tttcagatgc tggttcgacc aagtcaacca ttgtggatgc
    49081 ggcggagcag tatttggctg gcaagtctgt tcgctttgtc ggggcccatc ccatggctgg
    49141 tagtcacaag acaggggctg cttcggcaga tgtcaatctt tttgaaaatg cctattatat
    49201 ctttacacct tcaagcctga caagtcagga cacgcttaag gaaatgaagg atctgctttc
    49261 aggtcttcat gctcgtttta tcgagattga tgccaaggag catgatcgtg tcacttctca
    49321 gattagccat tttcctcata ttttggcttc tagtctcatg gagcagactg cggtctatgc
    49381 tcaagagcat gagatggcaa ggcgctttgc ggcaggtggt tttcgagata tgacccgaat
    49441 tgcggaaagc gagccaggaa tgtggacctc cattctcttg tccaatagcg agatcattct
    49501 ggatagaatt gaggatttca aggaacgttt ggaagcgatt ggtcaggcca ttagtaaggg
    49561 agatgaagag caaatttgga acttttttaa ccaagcgcgt gaacaacgcc agaccatgga
    49621 aatccataag cgtggtggtg tggatagctc ttacgacctc tatgttgacg ttcctgatga
    49681 agaagatgtc atcctgcgga ttttggaact gctacgtgga acttccttgg ttaatatcca
    49741 catcaacgag gaaaatcgtg aggatattca cggaatccta caaatttcat ttaaaaatgc
    49801 tcaagacttg gaaagagctg agcatctcat aacagaaaat actgactata cagtcgtcat
    49861 caaataagga gaagaacatg tcaaatattt acgatagtgc aaacgaactc agtcgcggtc
    49921 tacgcggatt accagaatac aaggctgtta aagcagctaa agatgcgatt gcagcagatg
    49981 ctgaggcaag caaaatcttt acagattatc ttgcctttca agaggaaatt caaaaactag
    50041 cacagacagg tcaaatgcca gatgcgtcct tccaagctaa gatggaaggc tttggtaaac
    50101 agattcaagg aaatagcctc ttgtcagaat tctttaccaa gcaacaacaa ttggccattt
    50161 acctttctga cattgaaaaa attgtttttg aaccagtttc agaattgctg aaataagaaa
    50221 agaactatcc taaagtcagg aatttttaag gaatttctgg ctttttatga taaaataggt
    50281 aaaagtattg caagtatgag gtccagtatg aaactaaaaa caaacattcg ccatttacat
    50341 ggtagtatcc gcgtcccagg tgacaagtct atcagccacc gttccattat ctttggaagt
    50401 ttggctgagg gtgagaccaa ggtttatgat attctgcgag gcgaagacgt tctttcgacc
    50461 atgcaggttt ttcgtgacct tggtgttgaa attgaggata aagatggggt tattaccatt
    50521 caaggtgtag gcatggctgg cttaaaagcg ccgcaaaatg cccttaatat gggaaattct
    50581 ggcacctcga ttcgcctgat ttcaggtgtc cttgctggtg cagatttcga agtagagatg
    50641 tttggagatg atagtctttc caaacgtcct atggaccgtg tgacccttcc actgaaaaaa
    50701 atgggcgtca gcatttcagg gcaaactgaa cgagacttgc ctccccttcg cttaaaaggg
    50761 acgaaaaacc taagccctat tcattatgag ttgccaattg cctctgccca agtcaagtca
    50821 gccttgatgt ttgcagcctt acaagctaag ggggagtcag ttattatcga aaaagaatac
    50881 acccgtaatc atactgaaga tatgttgcaa caatttggtg gtcatttaag tgtggatggt
    50941 aagaaaatca cagtccaagg gccacaaaaa ttgacaggac agaaggtggt cgtaccagga
    51001 gatatttcca gtgcagcctt ttggttagtc gcaggtttga ttgctccaaa ttctcgtcta
    51061 gtgctgcaga atgtggggat caacgaaact cgcaccggta ttattgatgt cattcgtgcc
    51121 atgggtggaa aattggaaat aactgaaatc gatccagtcg ctaaatctgc aaccttgatt
    51181 gttgagtctt ctgacttgaa aggaacagag atttgtggcg ctttgattcc acgtttgatt
    51241 gatgaattgc ctattattgc cctacttgcg acccaagccc aaggtgtaac agttattaaa
    51301 gatgctgagg agctcaaggt caaggaaaca gaccgtattc aggttgtggc agacgcctta
    51361 aatagtatgg gagcagatat tactcctacg gcagatggga tgattatcaa aggaaaatca
    51421 gctcttcacg gtgctagagt caatacgttt ggtgaccacc gtatcggcat gatgacagct
    51481 atcgcagccc tattggttgc agatggagag gtggagcttg accgtgcaga agccatcaat
    51541 accagctatc ctagtttctt tgatgatttg gagagcttga ttcatggcta aggtgttatt
    51601 agggtttatg ggggctggaa aatcaactat tgcaagaggc ttggacccta attaccttga
    51661 tatggatgct ctgattgaga agcgcctagg tatgtccatt gcgaattttt tcgctgaaaa
    51721 gggagaatca gcctttcgtc aggtagaatc agaagtccta gctgatttac tacaaacaga
    51781 ccaagtcgtg tcaactggag gaggagtggt tatttctcag agaaatcgtg acttactcaa
    51841 gactaataca gataacatct acctgaaagc agattttgaa accctctacc tacgtatcgt
    51901 agctgataag gacaatcagc gaccgctttt tctaaataat agcaaggaag aactagtagc
    51961 tatttttcaa gaaagacagg cttggtatga ggaagtggct agtcgggttt tggatgtgac
    52021 caagctaagc ccagaggaaa ttatagagga actaagatga aaattgctta tctaggtccc
    52081 aaaggatcat tttcacacca cgttgtgcag acagcttttc ctcatgagga attgcaggct
    52141 tttgccaaca ttacagatgt tatcaaggct tatgagcaag gattagtgga ctattctgtg
    52201 gtgccagttg aaaattctat tgagggtagt gttcatgaaa ccttggacta tctttttcat
    52261 caggctcaca tccaagcagt agcagaaatc gttcagccta ttcatcagca gttgatggtg
    52321 gttccaggcc atactaagat tgaaaagatt ttttcacatc cacaggcctt ggctcaagga
    52381 aagaaattca tcgatgaaca atatccagag gctcaaatcg aggtaacagc tagtacagct
    52441 tatgcggccc gttttatttc cgaacatcca gaccagccct ttgcagcagt tgcacctaga
    52501 agttctgctg aagaatatgg attggaactg attgccgagg atattcagga aatggaagcc
    52561 aatttcacac gtttctgggt tctaggagct gaaaagccta gtattccctt gcaagcacaa
    52621 actgaaaaga tgagtttggc cttgacatta cctgacaacc ttccaggtgc actttataag
    52681 gccctgtcga cctttgcttg gcgaggaatt gacttgacaa aaattgaaag tcgtccactc
    52741 aagacagcac tgggtgaata ctttttcatt atcgatgtgg attataccga taaggacttg
    52801 gtccactttg cccaaaaaga attagaagcg attggaatcc agtataaaat tctgggtgcc
    52861 tatcctattt atccaatatc agaccatgga aaggagagaa gatgagtaaa gaaaatccct
    52921 taagtcatca tgagcagttg cgttatgatt atttgctaaa aaatattcac tacctcaatg
    52981 agagagaaaa aaatgagttt gcctatttgc aagaaaagct aactcttgct aggagaaata
    53041 gtagctctag cttggaacaa gaaagagaag agcaggttga cttaccaagt tatgcgaacc
    53101 ggagtcgctc acaatccaaa tcacaagcac tctcttcccc tccaaaaaag aaaagacgga
    53161 agctccgtct taaacgaatt tttatggtga ttttttcact tttggtctgt gtggctttgg
    53221 ccatggtatt catgtttttg cgtggttacc aagatgctag cgcaaagaaa actgctgatg
    53281 cccgggcagc tcaagtagaa gtctttaatg gtcaggacac tagagatgga gttaatattt
    53341 taatcatggg tactgatggt cgaatcggcc agaacagtgt tgagacacga actgactcta
    53401 ttatggtatt aaatgtcggg ggctcagata agaaaatgaa gctagtcagt ttcatgcgtg
    53461 ataatttggt ctatatagat ggttatagtc aagtgattaa cggtagaaaa cagacagata
    53521 acaagttaaa cgtagcctac gagttaggag aacaagaggg gcaaaaaggg gcagaaatgg
    53581 ttcgccaagt cttgaaagat aattttgact tggacattaa gtactacgcc ttggttgatt
    53641 tccaggcctt tgccacagcg attgacacac ttttccctga tggggtgacg attgatgctc
    53701 aattttcaac attgaatggg cgtcccctaa cagaagctac agtcggagat gatttatacg
    53761 ctaccgagac tgagtctcca acccaaacca ttaaagtcgg aaaacagcag atgaatggct
    53821 cgaccctgct caattatgct cgtttccgtg atgatgatga ggcggattac ggccgtacaa
    53881 aaagacagca acaagtttta acagcaattt tagagcaaat taaagatccc actaaacttt
    53941 tcactggttc tgaagctctt ggaaaggttt ttgctatgac ctcaaccaac gtaccctata
    54001 ctttcctcct aacaaacggt ttatctgttt tggatggagc aaaaaatggt attgaaaaat
    54061 tgacgattcc agaactgggt gactgggtag atgcctatga tgtttatgga ggcttgggct
    54121 tgctggttga tcaaaacaaa tatcaaacca agctcgctca aatgggcttg agataagata
    54181 atactcaatg aaaatcaaag tgcaaactag gaagctagcc gcaggctgct aaaaacacag
    54241 ttttgaggtt atagataaga ctgacgaagt cagttaccta tacctacggc aaggtgaagc
    54301 tgacgtgctt tgaagagatt ttcgaagagt ataagacaga aaaatcaaag tttgatagct
    54361 atttggatag cagtcaggct ttgatttttt acagtctgca atagattttc accccttgtt
    54421 tgtggtataa tgaaacgata cgatagaaag aataatgaac aatatgactg atttaaaagc
    54481 aattcaggct cgtagtctgg agatggctga atattttgtg gccttttgta aagaacatga
    54541 tttgctctgt tatctctgtg gcggaggcgc tattggtacc cttcgaaaca agggatttat
    54601 tccttgggac gacgacctag acttttttat gcctcgtaaa gattatgaga aattagcaga
    54661 attatggcct cgttatgcag atgaacgtta tttcttgtca aagagttaca aggattttgt
    54721 tgatcgtaat ctttttatta ccattcgtga caaggaaacc acctgtatca agccttatca
    54781 gcaggatttg gatttgccac atggtctggc cttggatgtt ttgcctttgg attattatcc
    54841 gaaagatcca gctgagcgga aaaaacaggt tcgttgggcc ttgatttatt cactcttttg
    54901 tgcgcaaact attccagaaa agcatggtgc tctcatgaaa tggggaagtc gcattttact
    54961 gggtttgact ccaaaatctc tccgttatcg catctggaaa aaagctgaga aagaaatgac
    55021 taagtatgat ttggctgatt gtgatggcat tacagaatta tgctcaggtc ctggctacat
    55081 gagaaacaag tacccaatca catcttttga agacaatctt ttcttgccat ttgagggaac
    55141 agagatgcct attccaatcg gctatgatgt ctatctcaga actgcttttg gggattatat
    55201 gacgcctcca ccagcagaca agcaggtacc gcatcatgat gctgtcatcg ctgatatgga
    55261 taagtcttat acagaataca agggagaata tggtggctaa gaaaaaaatc ttatttttta
    55321 tgtggtcttt ttctcttgga ggtggtgcag agaagattct atcaaccatt gtttcaaatc
    55381 tggatccaga aaagtatgat attgatattc ttgaaatgga gcactttgac aagggatatg
    55441 aatctgttcc aaagcatgta cgcattttaa aatcccttca agattatcgc caaaccagat
    55501 ggttacgagc ttttttgtgg agaatgagaa tttattttcc aagactggct cgtcgtttgc
    55561 ttgtaaaaga tgattatgat gttgaagttt cttttaccat tatgaatcca ccactgttgt
    55621 tctctaaaag aagagaagtc aagaagatat cttggattca tggaagtatt gaagaacttc
    55681 ttaaggatag ctctaaaaga gaatcacata gaagccagtt ggatgctgcg aatacaattg
    55741 tagggatttc aaaaaagacc agcaattcta tcaaggaagt ttatccagat tatgcttcta
    55801 aattacagac aatctacaat ggatatgatt ttcagactat tctagaaaaa tctcaagaga
    55861 agatcgatat cgagattgct cctcaaagta tctgtactat cggacggatt gaggaaaata
    55921 agggttctga ccgtgtagtg gaagtgatac gattattaca ccaagaggga aaaaactatc
    55981 atctctattt tatcggggct ggtgatatgg aagaggaact gaaaaaacga gtcaaagagt
    56041 atgggattga ggactatgta catttccttg gttatcaaaa aaatccttat cagtatttat
    56101 ctcagacgaa agttctcttg tctatgtcta aacaagaagg ttttcctgga gtgtatgtgg
    56161 aggccttgag tctgggactc ccttttatct ctacggacgt tggaggggct gaggaattat
    56221 cccaagaagg acgatttgga caaatcattg agagcaatca agaggcagct caggcgatta
    56281 ctaattacat gacttctgcc tcaaactttg atgtcgatga ggctagccaa ttcattcaac
    56341 aatttacaat tacaaaacaa atcgaacaag tagaaaaact attagaggag tagcatggaa
    56401 actgcattaa ttagtgtgat tgtgccagtc tataatgtgg cgcagtacct agaaaaatcg
    56461 atagcttcca ttcagaagca gatctatcaa aatctggaaa ttattcttgt tgatgatggt
    56521 gcaacagatg aaagtggtcg cttgtgtgac tcaatcgctg aacaagatga cagggtgtca
    56581 gtgcttcata aaaagaacga aggattgtcg caagcacgaa atgatgggat gaagcaggct
    56641 cacggggatt atctgatttt tattgactca gatgattata tccatccaga aatgattcag
    56701 agcttatatg agcaattagt tcaagaagat gcggatgttt caagctgtgg tgtcatgaat
    56761 gtctatgcta atgatgaaag cccacagtca gccaatcagg atgactattt tgtctgtgat
    56821 tctcaaacat ttctaaagga atacctcata ggtgaaaaaa tacctgggac gatttgcaat
    56881 aagctaatca agagacagat tgcaactgcc ctatcctttc ctaaggggtt gatttacgaa
    56941 gatgcctatt accattttga tttaatcaag ttggccaaga agtatgtggt taatactaaa
    57001 ccctattatt actatttcca tagaggggat agtattacga ccaaacccta tgcagagaag
    57061 gatttagcct atattgatat ctaccaaaag ttttataatg aagttgtgaa aaactatcct
    57121 gacttgaaag aggtcgcttt tttcagattg gcctatgccc acttctttat tctggataag
    57181 atgttgctag atgatcagta taaacagttt gaagcctatt ctcagattca tcgtttttta
    57241 aaaggccatg cctttgctat ttctaggaat ccaattttcc gtaaggggag aagaattagt
    57301 gctttggccc tattcataaa tatttcctta tatcgattct tattactgaa aaatattgaa
    57361 aaatctaaaa aattacatta gaacgggggt gaccaagtga ttgatgggaa acgattatta
    57421 tttagtttga ccatagtcag ttatgccttg acgctagtaa gtggaattgt gtatctgttt
    57481 aataataata atgttagctt actttctact ttattgttct tgttggttag tagcttaatt
    57541 gcttgttgga atgatatcaa gtattactta atccatttta ttttctattt aaccattttt
    57601 gtatttctgg tatcaagacc gaccattgat tattttaggg atggtgcttt ggatacctat
    57661 catccaatag cctatcgttt tgcctttata gttgtcatgg tttcgattct gggcttgacc
    57721 acaggaggca ttctggctcg ttacttcata gctaggaaga aaataaaagt agcaaatata
    57781 ggaaattctc taaaagaggt ttatatcaag cggttacgct ttgtatcact aggagttttt
    57841 cttctaacct atcctttcta tttcattcgg ttatttgaac ggctcttgta tcgtttgcag
    57901 acttcctact atgcctacta tgcaaatttt gaaagtaaac tgccttattt tacctacatt
    57961 ttgtctacct ttacggtcta tgcaatgtgt atgtatctgg caaccaagcc aaagaaattg
    58021 caggccacag cagtgcttgt ctcctttatt gcagctaata ctattcattt ggcaattggg
    58081 acacgaaatc cctttatttt aagtatttta tttgcttttg tttattactt tatgcgggag
    58141 caaactgaaa aaggaaaatg gattgggttt aaagaaaagt tagcgatttt tgtaggttct
    58201 cctattctca tgttagcgat gggagtactc aattatgtac gggataatgt ccaagtttcc
    58261 catacaggtt tctgggatat cttacttgac tttatctata aacaagggac tagttttggt
    58321 gttctggctc gaggttttct atttaacagt agcctccctt accgagattt ccgtaatttt
    58381 acttttggtc ctgttcttga ttattttgca agggggagtt tgggagccat tttcggagga
    58441 aaagcctttg aacatacaac caatagtgtg gaactagcta ttgatagtaa tagttatgcc
    58501 cacaatctat cctatcttgt cttgaacaag gaatacctga aagggcatgg tatcggaagt
    58561 agttatatca tggagttgta taccgactat ggtatgattg gagtctttct gcttagtttc
    58621 ttactcggcg tattatttat agccatgctg caagtagcct atcgctcaag gacaatccta
    58681 tttgctttat ccctactcat cttgaataat ctattcttta tgccaagaag cagcttttca
    58741 gaaagtttct tcaatttatt tacaatgcaa ttctggggaa ttgttcttgt gattatattt
    58801 atagcaaaaa tgcttacaaa ggaaaactag tatctactaa acaaaggaga aaaaaatcat
    58861 gtttgaacat tattcagtag ctgatttgtt tgcaaatctt tataaaaagc gaaaagcaaa
    58921 tattttagct ctcatcgctt tatttgctct cattgctgta ccatttacaa ttaaagcagt
    58981 taggaataaa aacactgtca aagatacaac aagttattca acttatctta tctataaaat
    59041 cactcctcca aaagagtcgg ccaaaacgat tttgaatcat caaattggtg gttatagtga
    59101 tttttatggg aaattgattg atggtaattt gaatggagct tatcttttca atgatgtaga
    59161 acccagtgag ttgaaaaaaa ttgccagtga attagacacg acagaaacaa ccttgaaaaa
    59221 ttcaacgaat gactattggt ggaaaaaatt gaccgtctac tatatgattg acgatgcagg
    59281 ggttggtgtg aaaattttga catcaagtaa agatgccaat gacttgttag agaaaaaaat
    59341 tgatgggttg attgagaaat ttaaacatgc ctatgcaaat gtgaaaattg aaaaactgga
    59401 aaccatcaac tctaaagaat tgaacgcaaa tggtgaaaca gcgcttggct taaatgtgaa
    59461 aaatctgatt cttcgtttag ttgttattgg agtggtttgt gtgattttgg ttgtgatggg
    59521 aaatgtgtta gtttatctct ttaatccaac aatcaataga gtaggtgatt tttctcagta
    59581 tcaaattgat tttgtaacag agattacaac aattgctaac ctagcagatg ttttgtcata
    59641 caaaaatact ggacaggaat tgaccatcgt tagctcaaat aaagctatcc tagataaatt
    59701 gaaacagagt caagaagctt taaaaggaat gcattttgta gatttacagg atgtatcatc
    59761 tcttttggaa agagatacag tccttcttgt tgaagagtac ggagtgactc gttataagaa
    59821 atttgagcaa agtcttcaaa ttctcagaaa cttaaatcgt tctatcctcg gtgtagcaac
    59881 ctttaaatta taagtattct gatgtataag gtcttcaaag tcggctaaga gccgattttg
    59941 aaggcttttt ctatctgtct gcagaaattt tcttttgata aaatcgtaaa aatctagtat
    60001 aatagataga actgaaagta tgaggttact agcaatgaaa atgaaacaaa ttagtgatac
    60061 aactttaaaa atcacgatat ctttagagga tttgatggat cgtggaatgg agattgctga
    60121 ctttctcgtt cctcaagaaa aaacagaaga gttcttttat gctatcttgg atgagctaga
    60181 gatgcctgat agctttctgg atacaggcat gttgagcttc cgtgtgactc caaaacctga
    60241 taaggtagat gtctttgtga ccaagtcaaa gattgaccaa aatctagatt ttgaagactt
    60301 atcggatttg ccagatatgg aagaattggc tcaaatgtct ccagatgaat ttatcaaaac
    60361 cctggaaaaa agcatcgcag acaaaaccaa ggatgatatc gaagccattc aatctcttga
    60421 gcaagttgaa gccaaggaag aagaacaaga gcaggctgaa caagaagctg agagtaagaa
    60481 agaaccttac atctactaca tcctttcttt tgctaagttg gctgacttgg tagcttttgc
    60541 caagacagtg acttttgaaa tggaaacttc tgaactctac aaaatgaacg agcgctatta
    60601 tttgaccatt ttagtggata ttgaaaatca tccaagccca tatccagctt ggctgttggc
    60661 ccgtatgcgc gagtttgcag aggatagtga tatcagtcgc tcagtcttac aagagtatgg
    60721 tcaagttttg atgagtcacg atgcagtgct caatctgcaa aaaatcggct aatcttttct
    60781 ggaaagctat tttcagattt taagaagagc gaatcgtctg attcgttttt tctttttata
    60841 ctgaaatagt gatttactat aataggaatt ttcacaaaat tctgttataa tggctatatt
    60901 agaaaatttc gaggagataa agatgacagt taaaattgct ttactaggat ttggtaccgt
    60961 tgcaagtggt gtgcctttcc tcctaaagga aaatggagga aaaatcaatc aatcagcaca
    61021 ttcagatatc aaagttgcta aggtattggt caaggatgaa gatgaaaaaa atcgcttgct
    61081 tgcagcaggg aatgacttta actttgtaac caatgtggat gatattttat cagaccagga
    61141 tattactatc gtagtggaat tgatggggcg tattgagcct gctaaaacct ttatcactcg
    61201 tgccttggaa gctggaaaac acgttgttac tgctaacaag gaccttttag ctgtccatgg
    61261 cgcagaattg ctagaaatcg ctcaagctaa caaggtagca ctttactacg aagcagcagt
    61321 tgctggtggg attccaattc ttcgtacttt agcaaattcc ttggcttctg ataaaattac
    61381 gcgcgtgctt ggagtagtca acggaacttc caacttcatg gtgaccaaga tggtggaaga
    61441 aggctggtct tacgatgatg ctcttgcgga agcacaacgt ctaggatttg cagaaagcga
    61501 tccgacgaat gacgtagatg ggattgatgc agcctacaag atggttattt tgagccaatt
    61561 tgcctttggc atgaagattg cctttgatga tgtagtccac aagggaatcc gcaatatcac
    61621 accagaagac gtagctgtag ctcaagagct tggttacgta gtgaaattgg ttggttctat
    61681 tgaggaaact tcttcaggta ttgctgcaga agtgactcca accttcctac ctaaagcgca
    61741 cccacttgct agtgtgaatg gcgtaatgaa cgctgtcttt gtagaatcta tcggtattgg
    61801 tgagtctatg tactacggac caggtgcggg tcaaaaacca actgcaacaa gtgttgtagc
    61861 tgatattgtc cgtatcgttc gtcgtttgaa tgatggtact attggcaaag acttcaacga
    61921 atatagccgt gacttggtct tggcaaatcc tgaagatgtc aaagcaaact actatttctc
    61981 aatcttggct ccagactcaa aaggtcaggt cttgaagttg gctgaaatct tcaatgctca
    62041 agatatttcc tttaagcaaa tccttcaaga tggcaaagag ggtgacaagg cgcgtgtcgt
    62101 tatcatcaca cacaagatta ataaagccca gcttgaaaat gtctcagctg aattgaagaa
    62161 ggtttcagaa ttcgacctct tgaatacctt caaggtgcta ggagaataag atgaagatta
    62221 ttgtacctgc aaccagtgcc aatatcgggc caggttttga ctcggtcggt gtagctgtaa
    62281 ccaagtatct tcaaattgag gtctgcgaag aacgagatga gtggctgatt gaacaccaga
    62341 ttggcaaatg gattccacat gatgagcgta atctcttgct caaaatcgct ttacaaattg
    62401 taccagactt gcaaccaaga cgcttgaaaa tgaccagtga tgtccctttg gcgcgcggtt
    62461 tgggttcttc cagctcggtt atcgttgctg ggattgaact agccaaccaa ctgggtcaac
    62521 tcaacttatc agaccatgaa aaattgcagt tagcgaccaa gattgaaggg catcctgaca
    62581 atgtggctcc agccatttat ggtaatctcg ttattgcaag ttctgttgaa gggcaagtct
    62641 ctgctatcgt agcagacttt ccagagtgtg attttctagc ttacattcca aactatgaat
    62701 tacgtactcg cgacagccgt agtgtcttgc ctaaaaaatt gtcttataag gaagctgttg
    62761 ctgcaagttc tatcgccaat gtagcggttg ctgccttgtt ggcaggagac atggtgaccg
    62821 ctgggcaagc aatcgaggga gacctcttcc atgagcgcta tcgtcaggac ttggtaagag
    62881 aatttgcgat gattaagcaa gtgaccaaag aaaatggggc ctatgcaacc tacctttctg
    62941 gtgctgggcc gacagttatg gttctggctt ctcatgacaa gatgccaaca attaaggcag
    63001 aattggaaaa gcaacctttc aaaggaaaac tgcatgactt gagagttgat acccaaggtg
    63061 tccgtgtaga agcaaaataa agaatagaag ataggatggg gaaactcttg accagagggt
    63121 ttcatatcct ttttgtgaaa agaagtttat actcaatgaa aatcaaagag caaactagga
    63181 agctagccgc aggctgctca aaacagtgtt ttgaggttgc agatagaact gacgaagtca
    63241 gtaacatata tacggtaagg tgacgctgac gtggtttgaa gagattttcg aagagtatta
    63301 gttaaaaacg tgataaagga gaaataaaga tggcagaaat ttatctagca ggtggttgtt
    63361 tttggggcct agaggaatat ttttcacgca tttctggagt gctagaaacc agtgttggct
    63421 acgctaatgg tcaagtcgaa acgaccaatt accagttgat caaggaaaca gaccatgcag
    63481 aaacggtcca agtgatttac gatgagaagg aagtgtcact cagagagatt ttactttatt
    63541 atttccgagt tatcgatcct ctatctatca atcaacaagg gaatgaccgt ggtcgccaat
    63601 atcgaactgg gatttattat caggatgaag cagatttgcc agctatctac acagtggtac
    63661 aggagcagga acgcatgctg ggtcgaaaga ttgcagtaga agtggagcaa ttacgccact
    63721 acattctggc tgaagactac caccaagatt atctcaggaa gaatccttca ggttactgtc
    63781 atatcgatgt gaccgatgct gataagccat tgattgatgc agcaaactat gaaaagccta
    63841 gtcaagaggt gttgaaggcc agtctatctg aagagtctta tcgtgtcaca caagaagctg
    63901 ctacagaggc tccatttacc aatgcctatg accaaacctt tgaagagggg atttatgtag
    63961 atattacgac aggtgagcca ctcttttttg ccaaggataa gtttgcttca ggttgtggtt
    64021 ggccaagttt tagccgtccg atttccaaag agttgattca ttattacaag gatctgagcc
    64081 atggaatgga gcgaattgaa gttcgttctc gttcaggcag tgctcacttg ggtcatgttt
    64141 tcacagatgg accgcgggag ttaggcggcc tccgttactg tatcaattct gcttctttac
    64201 gctttgtggc caaggatgag atggaaaaag caggatatgg ctatctattg ccttacttaa
    64261 acaaataaaa cagagagtgg ggcttcccac tttcttcatt tctagaatat gaatagaagg
    64321 gatttatgaa acacctatta tcttacttca aaccctacat caaggaatca attttagccc
    64381 ccttgttcaa gctgttagaa gctgtttttg agctcttggt tcccatggtg attgctggga
    64441 ttgttgacca atctttacct cagggagatc aaggtcatct ctggatgcag attggcctgc
    64501 tccttatctt tgcagtaatt ggcgttttag tggccttgat agctcaattt tactcagcaa
    64561 aggcagcagt aggttttgct aaggaattga caaacgatct ttatcgtcat attctttcct
    64621 tgcccaagga cagcagagac cgtctgacaa catctagttt ggtcactcgc ttgacttcgg
    64681 atacctacca gattcagact ggtatcaatc aattcctgcg tctctttttg cgagcgccca
    64741 ttatcgtttt tggtgccatt tttatggctt atcgaatctc aactgagttg actttctggt
    64801 tcttagtcat ggttgccatt ttgaccattg tcattgtagg gttatctcga ttggtcaatc
    64861 ctctctacag tagtctcaga aagaaaacgg accaactggt tcaggaaacg cgccagcaat
    64921 tgcaagggat gcgggttatt cgtgcttttg gtcaagaaaa acgagagtta cagatttttc
    64981 aaacccttaa ccaagtttat gctagattac aagaaaagac aggtttctgg tctagtttat
    65041 taacacctct gacctatctg attgtcaatg gaactcttct cgttattatc tggcaaggct
    65101 atatttcaat tcaaggagga gtgctcagtc aaggtgctct cattgctctt atcaattacc
    65161 tcttacagat tttggtggaa ttggtcaagc tagccatgtt gatcaattcc ctcaaccagt
    65221 cctatatctc agtcaagcga atcgaggaag tctttgttga ggctccagag gatatccatt
    65281 cagagttaga acaaaagcaa gctaccagag ataaggtttt acaagtccaa gaattgactt
    65341 ttacctatcc tgatgcggcc cagccttctc tgagatacat ttcctttgat atgactcaag
    65401 gacaaattct aggtatcatc gggggaactg gttctggtaa atcaagcttg gtgcaactct
    65461 tacttggact ttatccagta gacaagggga acattgacct ttatcaaaat ggacgtagtc
    65521 ctcttaattt ggagcagtgg cggtcttgga ttgcctatgt acctcaaaag gtcgaactct
    65581 ttaaaggaac cattcgttcc aacttgactc taggtttcaa tcaagaagta tctgaccagg
    65641 aactctggca ggccttggag attgcgcaag ctaaggattt tgtcagtgaa aaggaaggac
    65701 tcttggatgc tctagttgag gcaggggggc gaaatttctc aggtggacaa aaacaaagat
    65761 tgtctatcgc ccgagcagtc ttgcgccaag ctccgtttct catcctagat gatgcaacct
    65821 cggcactgga taccattaca gagtccaagc tcttgaaagc tattagagaa aattttccaa
    65881 acacgagctt aattttgatc tctcaacgaa cctcaacttt acagatggcg gaccagattc
    65941 tcctcttgga aaaaggtgag ttgctagctg ttggcaagca cgatgacttg atgaaatcca
    66001 gccaagtcta ttgtgaaatc aatgcatccc aacatggaaa ggaggactag aatgaaacga
    66061 caaactgtaa accagacgct caaacgttta gccgtagatt tagcaagcca tcctttcctc
    66121 cttttcctag cctttctagg aactattgct caagttggct tatcaattta cctacctatt
    66181 ctgattgggc aggtcattga ccaagtccta gtggctggtt catcaccagt tttttggcag
    66241 atttttctcc agatgctctt ggtggtaata ggaaatactc tggtacaatg ggccaatcct
    66301 ctcctctata atcgtctaat cttctcttat accagagatt tacgggagcg aatcatccat
    66361 aagctccatc gtttaccgat tgcctttgta gataggcaag gtagtggaga gatggttagt
    66421 cgtgtaacca cggacatcga acagttggca gctggcttga ccatgatttt taaccaattt
    66481 ttcattggtg ttttgatgat tttggtcagt attctagcca tgctccaaat tcatctcctc
    66541 atgactctct tagtcttgct gttgacgcca ctgtccatgg tgatttcacg ctttattgcc
    66601 aagaaatcct atcatctctt ccagaagcaa acagagacga ggggaattca gactcagttg
    66661 attgaagaat cgcttagtca gcagactata atccagtcct tcaatgctca aacagaattt
    66721 atccaaagat tgcgtgaggc tcatgacaac tactcaggct attctcagtc agccatcttt
    66781 tattcttcaa cggtcaatcc ttcgactcgc tttgtaaatg cactcattta tgccctttta
    66841 gctggagtag gagcttatcg tatcatgatg ggttcagcct tgaccgtcgg tcgtttagtg
    66901 acttttttga actatgttca gcaatacacc aagcccttta acgatatttc ttcagtgcta
    66961 gctgagttgc aaagtgctct ggcttgcgta gagcgtatct atggagtctt agatagccct
    67021 gaagtggctg aaacaggtaa ggaagtcttg acgaccagtg accaagttaa gggagctatt
    67081 tcctttaaac atgtctcttt tggctaccat cctgaaaaaa ttttgattaa ggacttgtct
    67141 atcgatattc cagctggtag taaggtagcc atcgttggtc cgacaggtgc tggaaaatca
    67201 actcttatca atctccttat gcgtttttat cccattagct cgggagatat cttgctggat
    67261 gggcaatcca tttatgatta tacacgagta tcattgagac agcagtttgg tatggtgctt
    67321 caagaaacct ggctcacaca agggaccatt catgataata ttgcctttgg caatcctgaa
    67381 gccagtcgag agcaagtaat tgctgctgcc aaagcagcta atgcagactt tttcatccaa
    67441 cagttgccac agggatacga taccaagttg gaaaatgctg gagaatctct ctctgtcggc
    67501 caagctcagc tcttgaccat agcccgagtc tttctggcta ttccaaagat tcttatctta
    67561 gacgaggcaa cttcttccat tgatacacgg acagaagtgc tggtacagga tgcctttgca
    67621 aaactcatga agggccgcac aagtttcatc attgctcacc gtttgtcaac cattcaggat
    67681 gcggatttaa ttcttgtctt agtagatggt gatattgttg aatatggtaa ccatcaagaa
    67741 ctcatggata gaaagggtaa gtattaccaa atgcaaaaag ctgcggcttt tagttctgaa
    67801 taagccattc tcttttgaaa gtttatggac gaaaaaagtt gccttcgagt gacttttttg
    67861 ttacaatagc tagaaaaatt gttcactgta atactcaatg aaaatcaaag agcaaactag
    67921 gaagctagcc gtaggttgct caaagcacag ctttgaggtt gtagataaga ctgacgaagt
    67981 cag
//
LOCUS       DAVHLA010000006        65471 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVHLA010000006 DAVHLA010000000
VERSION     DAVHLA010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 65471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65471
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.006"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(1..410)
                     /locus_tag="VVO77_000470"
                     /pseudo
     CDS             complement(1..410)
                     /locus_tag="VVO77_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255532.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
     gene            complement(412..1449)
                     /locus_tag="VVO77_000471"
     CDS             complement(412..1449)
                     /locus_tag="VVO77_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEU5692535.1"
                     /translation="MNQTINYIKELTAIASPTGFTREISDYLVHTLEKLGYQPVRTAK
                     GGVNVTIKGQNDEQQRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQTVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDAKVTNEKETRALGIEVG
                     DFISFDPRTVVTETGFIKSRHLDDKVSAAILLNLLRVYKEEGIELPVTTHFAFSVFEE
                     VGHGANSNIPTQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLRSNLVD"
     gene            complement(1547..2872)
                     /gene="brnQ"
                     /locus_tag="VVO77_000472"
     CDS             complement(1547..2872)
                     /gene="brnQ"
                     /locus_tag="VVO77_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEU5692536.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAVAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(3043..3135)
                     /locus_tag="VVO77_000473"
     CDS             complement(3043..3135)
                     /locus_tag="VVO77_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU5692537.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(3178..3330)
                     /locus_tag="VVO77_000474"
     CDS             complement(3178..3330)
                     /locus_tag="VVO77_000474"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU5692538.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDELAALHLEGTHNLPLSQ
                     LADSYD"
     gene            complement(3490..4068)
                     /locus_tag="VVO77_000475"
     CDS             complement(3490..4068)
                     /locus_tag="VVO77_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEU5692539.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFVAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     DFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMSKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(4122..5522)
                     /gene="pepV"
                     /locus_tag="VVO77_000476"
     CDS             complement(4122..5522)
                     /gene="pepV"
                     /locus_tag="VVO77_000476"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEU5692540.1"
                     /translation="MIAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFDFAGPAKEYLDITGKILLNDHEGESLKIAHVDEKMGALSMNAGV
                     FRFDETCADNTIALNIRYPKGTSPEQIKSILENLPVASVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLQGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(5535..6140)
                     /locus_tag="VVO77_000477"
     CDS             complement(5535..6140)
                     /locus_tag="VVO77_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEU5692541.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVCEKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            6311..7111
                     /locus_tag="VVO77_000478"
     CDS             6311..7111
                     /locus_tag="VVO77_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU5692542.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKESSSQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTYLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATIDFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSTDSPSN
                     YIVFSSDQKEFKEKFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(7289..8122)
                     /locus_tag="VVO77_000479"
     CDS             complement(7289..8122)
                     /locus_tag="VVO77_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEU5692543.1"
                     /translation="MNHKIAILSDVHGNATALEAVIADAKNQGASEYWLQGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEVLDGEYGLEYPKEIQSMRMTQFLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPDKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSKGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELLNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRREDNYQRHNLKLLASLIEKHRYVEDVKNFFDF
                     L"
     gene            complement(8112..9956)
                     /gene="uvrC"
                     /locus_tag="VVO77_000480"
     CDS             complement(8112..9956)
                     /gene="uvrC"
                     /locus_tag="VVO77_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEU5692544.1"
                     /translation="MNNLIKPKLELLPTSPGCYIYKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNEHYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKNDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVTAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGRPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSLTKIKEA
                     SVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP"
     gene            complement(9995..10696)
                     /locus_tag="VVO77_000481"
     CDS             complement(9995..10696)
                     /locus_tag="VVO77_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HEU5692545.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWPQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETNE"
     gene            complement(10775..12007)
                     /gene="murN"
                     /locus_tag="VVO77_000482"
     CDS             complement(10775..12007)
                     /gene="murN"
                     /locus_tag="VVO77_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEU5692546.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQNKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(12012..13232)
                     /gene="murM"
                     /locus_tag="VVO77_000483"
     CDS             complement(12012..13232)
                     /gene="murM"
                     /locus_tag="VVO77_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEU5692547.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(13344..14123)
                     /locus_tag="VVO77_000484"
     CDS             complement(13344..14123)
                     /locus_tag="VVO77_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEU5692548.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALTTNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(14192..15853)
                     /locus_tag="VVO77_000485"
     CDS             complement(14192..15853)
                     /locus_tag="VVO77_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEU5692549.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEDYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(16028..18250)
                     /gene="recJ"
                     /locus_tag="VVO77_000486"
     CDS             complement(16028..18250)
                     /gene="recJ"
                     /locus_tag="VVO77_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEU5692550.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKTYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            18527..19285
                     /locus_tag="VVO77_000487"
     CDS             18527..19285
                     /locus_tag="VVO77_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU5692551.1"
                     /translation="MVLVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAKKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLARDRMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            19325..20089
                     /locus_tag="VVO77_000488"
     CDS             19325..20089
                     /locus_tag="VVO77_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU5692552.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLKFK
                     FVELGSYPELITSLHAHRIDAFSVDRSILSGYTNKRTALLDDSFKPSDYGIVTKKSNT
                     ELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            20102..20779
                     /locus_tag="VVO77_000489"
     CDS             20102..20779
                     /locus_tag="VVO77_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU5692553.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLITLPQTFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGATLLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            20789..21448
                     /locus_tag="VVO77_000490"
     CDS             20789..21448
                     /locus_tag="VVO77_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU5692554.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLCILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            21706..22896
                     /locus_tag="VVO77_000491"
     CDS             21706..22896
                     /locus_tag="VVO77_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEU5692555.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHSLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVSSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTKNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(23217..24098)
                     /locus_tag="VVO77_000492"
     CDS             complement(23217..24098)
                     /locus_tag="VVO77_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEU5692556.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(24237..25565)
                     /gene="vncS"
                     /locus_tag="VVO77_000493"
     CDS             complement(24237..25565)
                     /gene="vncS"
                     /locus_tag="VVO77_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEU5692557.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(25562..26218)
                     /gene="vncR"
                     /locus_tag="VVO77_000494"
     CDS             complement(25562..26218)
                     /gene="vncR"
                     /locus_tag="VVO77_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEU5692558.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASFADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(26267..26350)
                     /gene="pep27"
                     /locus_tag="VVO77_000495"
     CDS             complement(26267..26350)
                     /gene="pep27"
                     /locus_tag="VVO77_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198524447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEU5692559.1"
                     /translation="MRKEFHNVLSSGQLLADKRPARDYNRK"
     gene            complement(26530..27909)
                     /gene="vex3"
                     /locus_tag="VVO77_000496"
     CDS             complement(26530..27909)
                     /gene="vex3"
                     /locus_tag="VVO77_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEU5692560.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(27961..28608)
                     /gene="vex2"
                     /locus_tag="VVO77_000497"
     CDS             complement(27961..28608)
                     /gene="vex2"
                     /locus_tag="VVO77_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEU5692561.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(28621..29898)
                     /locus_tag="VVO77_000498"
     CDS             complement(28621..29898)
                     /locus_tag="VVO77_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5692562.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNAITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
     gene            complement(30255..30425)
                     /locus_tag="VVO77_000499"
                     /pseudo
     CDS             complement(30255..30425)
                     /locus_tag="VVO77_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(30568..30714)
                     /locus_tag="VVO77_000500"
     CDS             complement(30568..30714)
                     /locus_tag="VVO77_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692563.1"
                     /translation="MKEANKNHPAGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVT
                     KYAR"
     gene            complement(30711..31166)
                     /locus_tag="VVO77_000501"
     CDS             complement(30711..31166)
                     /locus_tag="VVO77_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692564.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGHNFSSVSSS
                     SQTAKYEETGYNNNSSLYITIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEITVKIVSAKPTYPDKILVKNPDNIKDTEKMPLLKN"
     gene            complement(31303..32187)
                     /locus_tag="VVO77_000502"
     CDS             complement(31303..32187)
                     /locus_tag="VVO77_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEU5692565.1"
                     /translation="MRAKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            complement(32191..32577)
                     /locus_tag="VVO77_000503"
     CDS             complement(32191..32577)
                     /locus_tag="VVO77_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEU5692566.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            complement(32570..33913)
                     /locus_tag="VVO77_000504"
     CDS             complement(32570..33913)
                     /locus_tag="VVO77_000504"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEU5692567.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLDLGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLAAQGIKLLDTKDGVRWTRD"
     gene            complement(33995..34879)
                     /locus_tag="VVO77_000505"
     CDS             complement(33995..34879)
                     /locus_tag="VVO77_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU5692568.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEILLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKAGQVIGTCTVDLSTNT
                     NYLYGLAILEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            complement(34891..35508)
                     /gene="cysE"
                     /locus_tag="VVO77_000506"
     CDS             complement(34891..35508)
                     /gene="cysE"
                     /locus_tag="VVO77_000506"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEU5692569.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHGFKLLARMYSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            complement(35524..37737)
                     /gene="pnp"
                     /locus_tag="VVO77_000507"
     CDS             complement(35524..37737)
                     /gene="pnp"
                     /locus_tag="VVO77_000507"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEU5692570.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYANHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRLELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDYKPKKEFTETPKDSE"
     gene            complement(38296..39162)
                     /gene="metF"
                     /locus_tag="VVO77_000508"
     CDS             complement(38296..39162)
                     /gene="metF"
                     /locus_tag="VVO77_000508"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEU5692571.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            complement(39226..41475)
                     /gene="metE"
                     /locus_tag="VVO77_000509"
     CDS             complement(39226..41475)
                     /gene="metE"
                     /locus_tag="VVO77_000509"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEU5692572.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEANRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            complement(41736..42002)
                     /locus_tag="VVO77_000510"
     CDS             complement(41736..42002)
                     /locus_tag="VVO77_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU5692573.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGKTSPQLDTVLKVLASLGKTLAIVPLEQGKS"
     gene            complement(42128..42543)
                     /locus_tag="VVO77_000511"
                     /pseudo
     CDS             complement(42128..42543)
                     /locus_tag="VVO77_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            42699..43700
                     /locus_tag="VVO77_000512"
     CDS             42699..43700
                     /locus_tag="VVO77_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEU5692574.1"
                     /translation="MIKTFLSALSVILFSIPIITYSFFPSSNLNIWLSTQPILAQIYA
                     FPLATATMAAILSFLFFFLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NALPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            complement(43768..46173)
                     /locus_tag="VVO77_000513"
     CDS             complement(43768..46173)
                     /locus_tag="VVO77_000513"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEU5692575.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQINVGEEEERQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKKFTLTETNEAAADALSVSIETDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARDGEKLVTLDGEERDLAETDLVITVADKPVALAGVMGGQATEISEKS
                     SRVILEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASMIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVIQKLRRQVRTIAE
                     GAGLTEIITYALTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLQVTYTATSEIVSLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEGALQPAVPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(46250..46759)
                     /locus_tag="VVO77_000514"
     CDS             complement(46250..46759)
                     /locus_tag="VVO77_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU5692576.1"
                     /translation="MIRKVEMADVEVLAKIAKQTFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            complement(46759..47805)
                     /gene="pheS"
                     /locus_tag="VVO77_000515"
     CDS             complement(46759..47805)
                     /gene="pheS"
                     /locus_tag="VVO77_000515"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEU5692577.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            complement(48287..49702)
                     /locus_tag="VVO77_000516"
     CDS             complement(48287..49702)
                     /locus_tag="VVO77_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEU5692578.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWVDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDELNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGSGTLNRY
                     KKMSFTWYKEVIESNGESLFK"
     gene            complement(49715..51553)
                     /locus_tag="VVO77_000517"
     CDS             complement(49715..51553)
                     /locus_tag="VVO77_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU5692579.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGAPVTPASYGSSVVPILIMV
                     WLMKYIEKIIAKLTLAITKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVEAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(51571..52410)
                     /locus_tag="VVO77_000518"
     CDS             complement(51571..52410)
                     /locus_tag="VVO77_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEU5692580.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGIIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELAYLMAHIRRLTK
                     NLD"
     gene            complement(52710..54404)
                     /locus_tag="VVO77_000519"
                     /pseudo
     CDS             complement(52710..54404)
                     /locus_tag="VVO77_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268095.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            complement(54507..55492)
                     /locus_tag="VVO77_000520"
                     /pseudo
     CDS             complement(54507..55492)
                     /locus_tag="VVO77_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268095.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
     gene            complement(55595..55756)
                     /locus_tag="VVO77_000521"
     CDS             complement(55595..55756)
                     /locus_tag="VVO77_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000270801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692581.1"
                     /translation="MKEREVLTGQRLNELEINGIRLTKFKNGEIGIEFIWIDTENPPS
                     DAIGWVAKK"
     gene            complement(55778..56533)
                     /locus_tag="VVO77_000522"
     CDS             complement(55778..56533)
                     /locus_tag="VVO77_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HEU5692582.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSLEDLY"
     gene            complement(56604..59255)
                     /locus_tag="VVO77_000523"
     CDS             complement(56604..59255)
                     /locus_tag="VVO77_000523"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEU5692583.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VNLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIGKA
                     TANFDKFEFGVAGHILYNFIWDEFADWYVELTKEVLYSDNEEDKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAAYPTVNLAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIYLPLADLLNVEEELDRLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVARIDEMKKLVK"
     gene            complement(59267..60229)
                     /locus_tag="VVO77_000524"
     CDS             complement(59267..60229)
                     /locus_tag="VVO77_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-binding factor A"
                     /protein_id="HEU5692584.1"
                     /translation="MSDVKEEVSSLSEKQLRQIDVEYAELNDSDIIERLAYLEINNNE
                     KRIVISDIEPTKEIMSVSDQIFEIQKNFQKIKNMFELFISDVSDFLSIKNKLESKELE
                     IEEADVNRFMIHLLSSGKLFVDFNENQIKQKYSKDSEEFDCIHGFASYQYDTNFAYRF
                     CHSLRNYSQHTDLPINEVKAVSPDDETVIIDFYIDLDYLLNSNFKWKKLKGELIKLNQ
                     ETSKIDAIALVKEYFNALTELYGNYNKLFLKLNHNTLVDIKSKLESLKLKHSRYYISK
                     ISKYDLKYNPGNYTMSPLAAFAEIEEIYIELSKIGLVKIVNKSN"
     gene            complement(60231..60788)
                     /locus_tag="VVO77_000525"
     CDS             complement(60231..60788)
                     /locus_tag="VVO77_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU5692585.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSVDFNHRHEDDVLEIGY
                     TLHPDYWGRGYVPEAACALIDLAFKELGLHKIELTCFGYNLQSQRVSEKLGFTLEARI
                     RDRKDVQGNRCDSLIYGLLKSEWEE"
     gene            complement(60775..61224)
                     /locus_tag="VVO77_000526"
                     /pseudo
     CDS             complement(60775..61224)
                     /locus_tag="VVO77_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
     gene            complement(61637..62032)
                     /locus_tag="VVO77_000527"
     CDS             complement(61637..62032)
                     /locus_tag="VVO77_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEU5692586.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            complement(62128..62382)
                     /locus_tag="VVO77_000528"
     CDS             complement(62128..62382)
                     /locus_tag="VVO77_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEU5692587.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKAGKGFHDLPEGLFGERNY"
     gene            complement(62392..63726)
                     /locus_tag="VVO77_000529"
     CDS             complement(62392..63726)
                     /locus_tag="VVO77_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEU5692588.1"
                     /translation="MTDERIHILRDILLELHNGASPESVQDRFDATFTGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKGLREGSKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(63726..63959)
                     /locus_tag="VVO77_000530"
     CDS             complement(63726..63959)
                     /locus_tag="VVO77_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEU5692589.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            63990..64064
                     /locus_tag="VVO77_000531"
                     /pseudo
     CDS             63990..64064
                     /locus_tag="VVO77_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(64407..64589)
                     /locus_tag="VVO77_000532"
     CDS             complement(64407..64589)
                     /locus_tag="VVO77_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692590.1"
                     /translation="MNPIKAFAKIYGNYFLTVQGVKVMKTIKKADHVVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            complement(64591..65370)
                     /locus_tag="VVO77_000533"
     CDS             complement(64591..65370)
                     /locus_tag="VVO77_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692591.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELDPKDIPTL
                     LEQDPTTLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYAF
                     SLKLAQELGYIYGYEDLWASREELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLKIFGVNLTKGGLAKGIGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIKGE"
BASE COUNT        18944 a        14725 c        11913 g        19889 t
ORIGIN      
        1 tctcatccgg ttttgcttgg cgggtttctg cggtcatttt ttcaaaaggg acccaccaga
       61 ctggcccaca gtccttgaga ccgtggccat tcatatcacc tcttcgtcta gggaaaaggt
      121 gccagtggag atgggcatcg ccatttccta gaagttcaat attcattttc tcagcagtaa
      181 agcccttggc aactgcctct tggactaaac tcatttcttc tagaaaatgg agtcttgtgt
      241 ccttttctaa aatggtgcaa ttccgtgaca tgttccttgg ctagaaagag actatagctt
      301 gcaaaatact gatggtctcc aatcacaaga tagcctgttc ccaactcttt gacaaagtag
      361 ggattttctc ccttcttgat gagctcaatt ctctggcaaa taaggcacat atcaatctac
      421 taaattgctt ctaagatagg catcgaccat tcgttctgtt gcgaccaccg agtcaatatg
      481 agtgcgctca taagaatgac tagactcgat acccgcacca agaagggcat gcttgacctc
      541 tgcccctgca gacatagccg ctgaagcatc cgaaccataa aatggataga tgtccagctt
      601 aaaaggaata tcttgctctt tagccaaggc aaccaagtgt tgacggaagt catagtgata
      661 aggacctgaa gcatccttga cacagataga tactgtgtac tcatctgtct gctggtcatc
      721 tcccattgcc cccatatcga cagctagata ttccaccact tgagttggaa tattggaatt
      781 agcaccgtgg cccacctctt cgaaaactga aaaagcaaaa tgagttgtta ctggcaattc
      841 aattccctct tccttataaa cacgaagaag attgagcaaa attgctgcgc tgaccttgtc
      901 atccaagtgg cgagacttga taaaaccagt ctctgtcaca acagttcgcg gatcgaaact
      961 aataaagtct ccaacctcaa tacccaaggc gcgcgtttct ttttcattgg ttacttttgc
     1021 gtccaaacgc acttccatat tgtcctgcgt acgttctgca gttcctgcat ccttgtagac
     1081 atgacaagaa gtctggtgga tgaggatggt cccagatacc gtttgacctg tgctagccac
     1141 atgaacggta cagttttctc cttcaatcat gttccaagga aaaccaccaa tacgatccaa
     1201 tttgagacgg ccatctggtt tgactgcacg aacaatagca cccagcgtat ccacatgggc
     1261 tgtcacatag cgttgttgtt catcattttg acctttaatg gtcacattga caccaccctt
     1321 agctgtacga acaggctggt aaccaagttt ctctaaagta tggactagat agtctgagat
     1381 ctcacgagta aagcccgttg gagatgcaat agcggttagt tctttgatat agtttatagt
     1441 ctgattcatt tcttcacctc tttcgctacc tattataaca catttatcat cggataaaaa
     1501 aagaaaatca ctcctgtaga cttggctaca aaagtgattt aagtgattat tccatttcaa
     1561 aaacatcgct ttcttgcttg tttggtagaa ccaatgagag caagattcca acaatggctg
     1621 gcaccaacca tgggagagat gccttggcaa aaggaagaac gctaacaaga tttgcaagaa
     1681 actcaacctt aaacgagctt cctagtacgc ttgcaatggc aataactgta accacagcaa
     1741 ttgtcaactg catacctggt tttgaaaggg caacaaattt gttgacaatg acaatcataa
     1801 cgatagcaat cgtgattggg tacaagataa ccagtactgg aattgagtac ttgataatcg
     1861 catcaagacc caaattggca atagcaaatc caatcaaggt aaaggctgtc gcataaacct
     1921 tgtagctgat ttgtgggaag cgctcattaa agaactcagc tgttgacaca atcaaaccaa
     1981 cagtcgttgt gaagcaggtt acggtaacca tagctgcaag gaagagttga gctgttgagc
     2041 caaagatttc ttgagtggct tgtgacaaga tgtaaacacc tggtgttcca cccttcatcg
     2101 cttcagctgg tactgggaaa tgatttccaa gaaaacctaa accgatgtaa agagcgctga
     2161 aggcaagggc aacaacgata ccaacaaccc aaatagttga aatgtattct ttcttacttg
     2221 aaaatccaag ttgtttcaag gtttgaactg cgattacgct aaaggccact gaggcaaggg
     2281 cgtccaaggt attataacct tctaggaaac ctgtaccaaa ggcagaagct tgataagcag
     2341 ctgaagcagc ttgaggactt gttccaccat atttgatagc tcccagaacg accaagataa
     2401 caatcaaaat tgcaaagact ggcgttaaaa tacgtccaat gcggtctaag atttttgatg
     2461 gattaagcga aatcaaatag gctaccgcaa aatacagaac cgtaaataca atcaagccaa
     2521 gtcctttatt tgcatccgac aaaagggggc taatccctac ttcgtaagct gttgtagcag
     2581 tacgtggggt agcaaagaat ggaccgattg acaagtaaag aactgagagg taaagagtcg
     2641 caaaccaagg cgctatcttc gttgaaatct cgtagatata tcctttagga tttagcgttc
     2701 caataataag ggtcaagacg gcgataccaa cgcctgaaaa gacaaaacct gcgatggcag
     2761 gaagaaaatg ttctccagat agagcaccta gagaaggcgg aaaaatcaag ttccccgcac
     2821 caaaaaatat tccaaacagg agcaaacctg ttagggtacc ttttttagcc ataaaaatct
     2881 ccttcatatt tataaaatac tgacctagta taccacgatt aggagtctga aaaaagcatc
     2941 acgaggcaaa tattaaatgt tttcaatttt cttaaaaata agaattatct aaaaacaaaa
     3001 ctctcctacc cagtccacac caagtaggag aaatgcaaaa ttttaaagtt cttcaaaggc
     3061 taacatgcca ccctggacat tgataacatt ataaccttgt tctaacagga attggcaagc
     3121 acgcgccgat ctcattccag atttgcaaat aatataatgc aagcgatctt tgtccaatta
     3181 atcataacta tcagccaatt gactaagcgg taggttgtgg gtaccttcta aatgaagagc
     3241 tgcaagctca tccacttctc tcacatccac tagagaaagc tggtcgtttt ggtaaagctg
     3301 ataaaatgcg tcaaaggcta tttctttcat tctttttctt ctaatactct tcgaaaatct
     3361 cttcaaacca cgtcagcgtc gccttaccgt gcgtatgtta ccgacttcgt cagttttatc
     3421 tgcaacttca aagctgtact ttgagcagcc tacgactagc ttcctagttt gctctttgat
     3481 tttcattgac tataaaatgg ttttaattct ttttttcaaa tctggcacta cttctgcctc
     3541 aaaccaagga tttttggaca tccagatttg atttcgtggt gatgggtgaa ctagcggaaa
     3601 ataggctggc agatagtctt tatagtgttt caccctctcc gttaccttcc cactgatttt
     3661 ctcctgtaaa tagtaggctt gggcatattg cccaatcaag agggttaact gaatatcagg
     3721 caattcctgt aagagctgcg gatgccattt ttctgcaaaa tctgtacgag gcggaagatc
     3781 acccgacttg ccatgtcctg gaaagtagaa atccataggc aaaacagcaa aataacctga
     3841 attgtaaaag gtatcttcat ccacacctag ccagtcccgc aagcggtcac cacttttatc
     3901 tttccagtaa aggcctgctt cttgagtttt aagtcccgga gcctgaccga tgatattgat
     3961 gcgagcagtt tttggcgcta caaagagagg ctcaatgcca cgctctgtat agctggcatt
     4021 ctgcgaatcc gccatgatag cctgtttgat tctttcgatt tgagacatct actttccctc
     4081 caaaaagaag tccaagcata agatctcaga cttctatcgt tttatttgat caattcgtaa
     4141 atagcttcgg cataaattgc tgctgctcgg aagagatcgt ccaaggcaat aaattcattg
     4201 gcttggtgca tagtatcaat tgagtctggg aacatagcac cataggcaac tccgcgctct
     4261 aacaagcgac caaaggttcc accaccgatg acttgttcat gaccttgtag gcctgtttgt
     4321 ttttcataga cattcaacaa ggtttgcaca agtggatctt ccattggcac atagtgaggg
     4381 gtatgaccat gttctgatag actgacagaa gcaactggca agttttctag gattgacttg
     4441 atttgttctg gacttgttcc ttttggatag cggatgttga gggcaatggt attatcagca
     4501 catgtttcat cgaagcggaa gacgcctgca ttcatagaaa gggcacccat cttttcatcc
     4561 acatgagcaa tcttgagact ttcaccctca tggtcgttca agagaatttt accagtgatg
     4621 tcaaggtatt ctttggctgg accagcaaag tcaaactggc taaggaagag ggctaggtaa
     4681 gtcgcaccat tgacacctga agcaggcata gcaccgtggg ctgatttacc aatgatcgtc
     4741 accttgtatt tgccagcttc ttcttggagt tctcctctaa gtttgtgttc tgcaacaaag
     4801 gcatctagtt tagcttgcaa gtcagccaaa tcacctgaaa cgactgctgt tgctgattct
     4861 ggtaccatat tttcacgtaa accacctgta aagctgtgaa gacgggcagc acctgtattt
     4921 tctcctgcaa agtggaggta ttccgtgata tttccttttt caccattgat gatagggaat
     4981 tcagcgtctg gagagaaacc gaaatctggt ttggcaagtc ctacgtgctc aaagtagtag
     5041 tccatatctg cccagcctga ttcttcgtct gttccaacga tgaagcgaac tttcttagaa
     5101 gttggaagac ccaattcttt gatgattttc aaaccatagt aacaagctgt tgtaggaccc
     5161 ttatcgtccg aagccccgcg cgcataaagg cgaccatctt tgatagttgg tgtgtaagga
     5221 tctgtatccc aaccgctacc agctggaacc acgtccatat gggcaaagat tccgagaact
     5281 tcttctccat caccaaactc aaaatgtcct gcatagttat caacattttt agttggataa
     5341 ccatcacggt ctgcgatttc aaggaatttt tccaaggctt ttactggacc aggtccaaat
     5401 ggatgttggg catcagcctt gctatcatca cgttctgagt tgatttccaa aaggctaaac
     5461 aagtcagcca agaggtcttc tttgcgtttt tctacttctg ctgtaaaatc aattgctatc
     5521 attttttctt cttcctatct tttttcgatg atttcatcta ctggcaagcg gtagcttggt
     5581 tccaatttgt cgtctgtgta acccactgtg atcaagagtt ctgggcggaa acggtcttcg
     5641 atttccaaaa cttcattaac ttttgatttg tcaaaaccaa ggataatatt ggaaccaatt
     5701 ccttggtctg taagagcgag aaccaagttc atagcaacca aacctgcatt gagtgctagg
     5761 tagtcgctga cttgttgttc attgtagcgt gcaaattcag ctggcaaatt tttcatgaag
     5821 tattgaagtt gttcttctga gaaattgtta gcaccaccaa ctcgggcaat cttacgagcg
     5881 cgtttggcaa ggtctgtatc tgtaaatagg gcaatggtta caggtgctga tgatacctgt
     5941 tcaaaattgg aaccataagc taactttgcc agttcagcat ttttctcaca taccaccaca
     6001 aatttccaag gctggctgtt gtgggcgctt ggcgccaagg ttgcaatttc gatagccgta
     6061 cgcacatctt ttggatcaac aggcttatca gtgaaatgct tggtcgcatg acgtttttta
     6121 tttaattcaa gaaatttcat aatcgatttc cttttctaat tctactgctt ccattctacc
     6181 ataatttgaa agagcttgca gggatttttc atgattaagt ttttctatca cagacataaa
     6241 agatatatat tggtttatca ggaaagtttc tgataaacta gcaagtactt tacatttgaa
     6301 tggagacagt atgaaaaaat ttagcctatt actagctatc ctaccatttt tggttgcctg
     6361 tgggaatcaa gctacaccca aagagtccag ctctcaaaag acaatcgtcc ttgctacagc
     6421 tggcgatgtg ccaccatttg actacgaaga caagggcaat ctgacaggct tcgatatcga
     6481 agtcctaaaa gcagtggatg aaaaactcag cgattacgag attcaattcc aaagaactgc
     6541 ttgggagagc atcttcccag gacttgattc tggtcactat caagcagcag ctaataattt
     6601 gagttacaca aaagagcgcg ctgaaaaata cctctactcg cttccaattt ccaacaatcc
     6661 cctcgtcctt gtcagcaaca agaaaaatcc tttgacttat cttgaccaga tcgctggtaa
     6721 aacaacacaa gaggataccg gaacttctaa cgctcaattc atcaataact ggaatcagaa
     6781 acacactgat aatcccgcta caattgattt ttctggtgag gatattggta aacgaatcct
     6841 agaccttgct aacggagagt ttgatttcct agtttttgac aaggtatccg ttcaaaagat
     6901 tatcaaggac cgtggtttag acctctcagt cgttgattta ccttctacag atagccccag
     6961 caactatatc gttttctcaa gtgaccaaaa agagtttaaa gagaaatttg ataaagcgct
     7021 caaagaactc tatcaagacg gaacccttga aaaactcagc aatacctatc taggtggttc
     7081 ttacctccca gatcaatctc agttacaata acactcttcg aaaatctctt caaaccacgt
     7141 cagctttatc tgcaacctca aagctgtgct ttgagcaacc tacggctagc ttcctagttt
     7201 gctctttgat tttcattgag tataagatat ataaaagcga ttggactacc aatcgttttt
     7261 agtttgcatt ggttatttta ggaaactctt acaaaaaatc aaaaaaattc ttcacatcct
     7321 ctacatacct atgcttttct attaagcttg ctaatagttt cagattgtgc ctctgatagt
     7381 tatcttcacg acgtagttct tcatacattt cgataaaggg aagccccttg gatttggcca
     7441 attctaactc agcctcgtaa tcataagcaa ctttacgaaa ttggatattg agtaattccc
     7501 catcttcaac ctctatcacg gcatactggg cacggtgatt ttttaacgcc tcccaattaa
     7561 aatagggcat gccaatcgac cctggattga tgatttgttg ccctttactg ccgtagcgaa
     7621 gcaactgctt gtgaacatga ccataaactg ccacgtccgt ttccgcatct agcagttggt
     7681 caaatttctc tgtatcattc tcaactagca agtcaccacc atagtttttg tcaggtaaat
     7741 tatgagagat agaaaagcgc aatccgtcaa tttctttctt ttccagcaaa ggcaagcttc
     7801 gtagccagac aatcgttgca ggatccattc gctccatcaa aaactgggtc atgcgcattg
     7861 actggatttc tttcggatat tccaaaccat attcgccatc caagacctca aggacacgat
     7921 catcccaatt gcctcgaaca cttgctgtga taggaaggtc ctttagcagg gcgactaagt
     7981 catttgcgcc tggaccagga agaaaaatat ctccctgaag ccaatattca ctggcccctt
     8041 gatttttagc atctgcaatc actgcttcta gcgccgtcgc attgccatga acatctgata
     8101 aaattgcgat tttatggttc attgtggttt ccttccgttt ggtaatctac tctttcttct
     8161 gctacttgag gcaaggcttc tccctgcggg ttcaactttc tttgcacagc ctctgcaacg
     8221 actctaggta ccccaacttc gacaatctca tccacactgg cttccttgat tttggtcaaa
     8281 gacttgaaat gcttcataag attctgcttg cgtttaggtc ccagaccgtc aatcccatcc
     8341 aattgagatg agaaagaatt tttggagcgc agttggcggt ggaaagtgat agcaaagcgg
     8401 tgcacctcat cttggatgcg ttggaggagg aaaaattcct gagaattgcg agacaagtcc
     8461 accacctcaa gcggatctcc aaagagcaat tcatgggttt ggtgcttatc attcttttgc
     8521 agcccagcaa ttggaatatc caagcccagt tcctcttgga tgacttgctt agcaatattg
     8581 acttgacctt gccccccatc aatcacaatc aaatctggag gagtcaaagc ctcacgctgt
     8641 actcgaccat agcgtctgcg aatgacttct ctcatactag catagtcgtc cggcccaaca
     8701 acggttttta tcttgtactt acggtaatct tttttacttg gcctgccgtt aacaaagacc
     8761 accatggctg aaacaggact ggtccccatg atgttggagt tatcgaagga ctcgatgcga
     8821 actggagtcg gaatttggag caaacgtcct agattttcaa tagctccttg ggtcttttcg
     8881 actgattttt ctagcagatt gaacttctgc tctagactaa cacgagcatt ttttatggct
     8941 agattgacca gctgtttttt ctctccacgt tggggtttga gaatcttggt atccaccaaa
     9001 gccttgacag cttcttcgtc aatatcctgc ggaatcagta cctcattggg aactaggtga
     9061 gatttttctt gatagaattg tcccacatag gtcaagaaat cctcatctgg atcattgaag
     9121 taggggaaga gattgacatc gcgctcgatg agcttgccct gacgaacaaa gaaaacctgc
     9181 acacacatcc agcccttatc cacatagtag ccaaagacat cgcgattttg gagatcctta
     9241 gccatgaccc gttgcttggt tcgaagtgtt ccaatggcct gaatcaggtc acggtattcc
     9301 gctgcccgtt caaactccat actttgtgct gttactgcca ttttactctt gagatcatcg
     9361 atgattttgt catcctgacc tttcagaaaa tcagacacct cctgggccat ggacttgaaa
     9421 taggcctcgt cattcttaca gatggtgtgg gccatacatt ggccgatatg gtagtaaaaa
     9481 cagaccttag agggcgggtt ggtacatttt cgaaaaggga aaatcctatc tagaagtcgc
     9541 ttgatttcat tggctgcccc cacatctgga taagggccaa aataaagacc accgtccttt
     9601 ttgacctgac gagtaatgat aagccgtgga tagtgctcat tggtgatttt gataaaagga
     9661 taagacttgt catccttgag catgatattg tacttgggct tattttcctt gatcaggttg
     9721 atttccagca gaagcgcctc aatattagac tccgtaacaa taaattcaaa atccacaatt
     9781 tcagacacca aggcctctgt tttggtatca tgacttccac ggaaataaga cctcacgcga
     9841 ttacgcagat ttttagcctt tcctacatag ataatggtgc cgtttttatc cttgtaaatg
     9901 tagcaaccag ggctggtcgg caagagctct agttttggtt taatcaagtt gttcatagtt
     9961 ccattatagc aaaaaagtag ggaaagatag taccctactc attagtctca tatatttttc
    10021 ggaggtttgc aacatcctct tcctggatac cataaaagga acctgctggt tgcatgacag
    10081 acttctcatc tgtatggtcc aagccaatcg catgacctaa ctcatgttct gccgtatgga
    10141 caaggcgttc ataggaatag ccatagtatg gattggacaa ataataatga ttcaaccgca
    10201 ccgttacgga caagaattgc cctgttaaga gattagtttg actttccgcc tctcctgcca
    10261 caggagtgcc tccgtcgttc atctccgtag ccgtaatatc cgccttacta gactcagtca
    10321 cgagttcaaa gttaaaagca ccagtttgat tccagttctg gattgcttct aaataagcct
    10381 cttgaaagcg tgaatccatc tgcggatcca ggtaaatacg agcagaggcc tgtggccacc
    10441 ttccttcaga atgctggtga ctatctgtct ggcttaactt aggcagttgc cctgttttct
    10501 cccattggtc aatactttgt tgaccaattt ttactgaccg ttctgcttgc tttagcgctc
    10561 cttgaaaatc cccgttcaga taccagagaa gtccgaaagc aagcacacat aagagcacaa
    10621 ctatccaaac cagacgccaa aacaaacgcc acacaaaaga aaagaaagcc cctatcaaac
    10681 gaaaaagcca gcgcatgtct ctccaccttt ctagcaaata aaaattattt tactaaaaga
    10741 agctaaaaga aatctaaata ctgacttttt catcttaacg tcctactatt tttttgagta
    10801 actggatagc tttgtatttt aaaggagatg gatggtaacg gaaagtacct gctttgcgta
    10861 caatatagcc attaaaattc tgtttaaaac gcaaaacacc atcacttcca tcaaaaatcc
    10921 cttgaatgcc taggaagttg tatttaggta ttccacgttt tatgctttcc aacataacat
    10981 atttttgaag cagtgcaggg gcatagaact tattaaactc agtgtaggaa ccactaaaga
    11041 gataagtcgt ttcctgaggc atataaacaa ataaactccc agctaaaaca atatcttctt
    11101 ctccatattt ttcaatcaag tctcgcgctt ctgcttttcg aacttcaaac gtttcaaatt
    11161 gactagaata ttctctcagt tgattttgtt ttttctcaga atgaggattt ttactcaaat
    11221 caagtcgcaa cttgtccaag ttttcttcta gtttattttg ttcaccttgc aatttgctca
    11281 tatagtccga aaaatttaag cttgctatga gaaactccgc ttgttctcca aaagtatcat
    11341 aaaaatgctc ataatattct aaacttttat cactatattc tctacgttca gaggtttctt
    11401 ttgttatatt cttaaaaatc gatagttctt cacgttttaa ctttttcaat cgaatgccaa
    11461 aggtttcagc ctttttcacc aagggtttac cctttttgct aaaactttta agcaaactct
    11521 tttcagttaa ttcagttaaa tctttatagt ataaccaatc tggttctcca cctgggtaac
    11581 ctgttgttaa gccatcaaat tgataaccta aatcagtcaa accttgaata atactttttt
    11641 tctcagcatc tattggatta ccttggctat caaaagtttg ataagtttca taaggtttta
    11701 caagcaactc taatacacca ttttgcttgg catattcttt taactctgca taaaaaactg
    11761 gaagagcatc ttgttgggta taaatcggcc ccgaattgag ttccatatgc agaccaccca
    11821 gcatgggcaa gctataaacc agagctgcaa cttgaatttc tccttcttgt ttcaaagcaa
    11881 gataaacaat tcgagcccct cttttttcta gcaaatcccc catctggaca gattgcataa
    11941 aggaacgaga agaaacctga tcagaataag tctgaaactc ttctttcgtg agtgttgtta
    12001 gtgccatata cttactttct atgttttttt cttaatgttt tacggaaatc aagagcaagt
    12061 cttaacagag gatagagagg atgagtgggc attgtaaatt cacccaagta ttcttcaatc
    12121 gttggattaa atttttcctt aaaatgataa agtccaccat tgagagagtt ttcaacacca
    12181 cctaaatttt gccagaccat acctcgctca aaggcatagc gagccgtttc ataccatgtt
    12241 aaaattggtg cattgtaacg tttaaaatca tcatccatac cagcatatat attgacagag
    12301 gtagtaccaa attccaaact caaagtagcc gctaaaggaa ctctcgcttg acctacatct
    12361 atatattcct gcaagaaggt caattcctct aacaaacgtt ctttttcctt cttctgcgct
    12421 tctacttttg aagttcgagt cgactcagta aaggtctctt ccaaggctct atttttcgct
    12481 aactgttctt ctaattcttg cgaacgttta gaaacatcca aggtggccaa ggtgatatag
    12541 gccttgtcct taaaattatc taacaatttt ttataatagg cttcattcct caaatgaatc
    12601 tcttttcgct tctcagtttt tttcatcaac tccgaaaatg aatctaatag ttccagtcca
    12661 ccatattgaa tctcaagccc tttgtttcgt gctgttcgaa tagcctgttt tgttgacttg
    12721 gaaagtttat cttcttcaaa attttccttg tatattttcg cctgaatacg aggttgaatg
    12781 gtgtctccca tttcctccgt ttttcctgac caccttactc ccatttgttg caaactatca
    12841 ataatagcca gattttcagg aaattctgtc ttttcctgat tgattaaact ttgagatagg
    12901 caaatacttg ggtcaaaagt cacaaaaacc gctctcttac tgcgagcata ggacttaata
    12961 gactgaatgg caaaattcaa gagttcttta tccccataat ccaatatagg tcctcttggg
    13021 atgtaaaaca ttttatagcc tagcggaaga gttctaatca aaatactagc tgtcgccagt
    13081 aatttttctt ccctgtaaac accaaacttc tcatgttgcc aattagactt aacttcctcc
    13141 caagcactac tttgtaatac attggctaat tcatgttctt tgacaaactg atcatattct
    13201 aatgtgggaa tgccaatttg ataacggtac atttcctact ctctttcctc cagtatttta
    13261 ttactattct actactttcg tttgaaaagt ctagtgaaaa catattttat tttagttcta
    13321 ctccccctat gctgaagttc aaactaagtc agtctctctt ctaatttgaa atcaattggt
    13381 agggttgtta aaaaaacttc caattgtttt tcccagtagt accactcgtg agttccagca
    13441 ctatggctat aggtcacatc aaaacctagt tttttgagat ttttcactgc gagattattg
    13501 gcttcgtaca agaaatcctg ttcgccacac cacgcccaaa gtttggtctt tttatccgat
    13561 tttttagcca gactttcaag agaataggga ctagttgtcc agtctctaat ctctccaaaa
    13621 acacctctcc agtaggctgg acttcccaga ttttgacttt caggagaaaa gttttgaaag
    13681 ctgagggcac ctgaaaaact agctgcatga gaaaaacgat ttgtcgtaag agccagtttg
    13741 aagcagccgt agcctcccat agaaagacca gcgataaagg tcttttcacg cttgctagtc
    13801 atattaggga agaagcgttt cagaacctgc ggcaattcct ctgctagagc cgtgtagtag
    13861 tcaaaaccat actgggtatc ggtgtaccaa ccattgctgg tattgggcat aacaacgatg
    13921 agattagttc ctcgaagcaa gcgttctaca ttggtccgct taagccaact attatgattt
    13981 ccagacatcc cgtgcaaaag gtacaagacg ggaatatctt cacactctgg ttcttccact
    14041 cgattggcat cagggtagag gacattcacc ccccactcca tatccaatac ttgtgagtaa
    14101 tactcgattt tcattactgc catgattttc tccttctatt tttctataag aaaaagccga
    14161 aactcgactt tctctctgtt tatttcaacg attattttgc ttccatgact actggtaaaa
    14221 tagctggacg acgcttggtt tggtcaaaga gatacttggt caaattatct cgaaccttcc
    14281 ctttaagatc tgcccagtca aagtcatctc cttgaagata atcttctacc gtttggttaa
    14341 tcaattctga actttcacgg agaatatcgc gactcttctt gagataaaca aatccacgcg
    14401 tgtgaacacg agccctagcc acaattttct tctcacgacg gttgactgta atagccacga
    14461 tgaaaattcc atcctctgac aagaccttac ggtcacgaag aacaacattt ccaacatcac
    14521 caatggcatt cccatcaatc aagatatctc ctgctgaaac cgatccagct ggaacaaagt
    14581 ctccattctc gtaagccatg gtcgtcccct ttttaggaat gaaaatgcgt tctggcaaca
    14641 tcccaactgc catggcagcc ttagcgtgag catccaactc acgatactcc ccttggacag
    14701 ggaagaggta cttaggttgc aaaagattga tcatcagctg caaatcacgc acatttccgt
    14761 gccctgatac atgtaaactt tgggtaatca atttgacaac cccacctgcc tgataaatca
    14821 tattttccac acgcgcaaca aaggcttctt tagcaataga cggagccgta gcaatataga
    14881 ccaggtcccc atccttgatt tctacataac gatggcgacc aatcgacatc ttacgaagtc
    14941 cattgatagg ttcacccata cgacctgtct caagaataat caactcatgg tcttcaaagc
    15001 gagacatatc tttaggctta atcaagagaa tttcgttggc taaagacaac ttcttaagac
    15061 gaatcgctgt gcggacgata ttttcaatat caaatcctgt caagacgata cgtcgacctg
    15121 ttttatccgc agcgtcaaaa atctgctgaa tacgagaaag attactggaa acagctgcaa
    15181 cgatgatacg accttcccag tcagcaatag tttgggtaat ttcatcccta acttcacttt
    15241 cactagccac ctgaatattg ctgtctgcat tggccgaatc actgaggaga gccaggacgc
    15301 cgtcacgacc aatctctgcc aaacgagcaa aatcagttgc ataagattca ctagccgttt
    15361 ggtcaaattt gaagtcacct gtataaacga tgcttccttc cgatgtcttc aagacaattc
    15421 ccagactctc tggaacggag taagtcgtag ggaagaagga aaccactgtc ccaccaaaat
    15481 caatctccgt attctcatca atgacatgga aatcattaaa tttcttaacg gcatcatttc
    15541 ctttgacaaa gagctttgcc aactcaatgg tcaactcaga cccaaataca ggaactttag
    15601 cctctgccaa gagataaggt agagcaccaa tggcatccgc atgcccgtgg gtcaagaaaa
    15661 ccccagcaat acggtcgcta ttttcaaaaa ggtaatccat gtttggaatc accacatcga
    15721 cccctaattg ttcattttca ggatatttta accctacatt caaaacaaaa atggactctc
    15781 caatttcagc aatgtacata ttttttccat tctcacgcac accaccaagt gttgttaaac
    15841 tgatattact catttttcct ccaaaatctt agtttatctt gattataggg caattctacc
    15901 ctcttattct aaaagttctg atactttcag ccgaatcttt tcctaccatt ataccatttt
    15961 tttgatgatt ttcaaaatga aggtctgttt tcaaaaaaga gttgatttcc caactctttc
    16021 ctaacttcta ctctttttcc atcaaaaaat cataaatttc ttgcaccgta cccagcgcca
    16081 tcatttcttg gtctttaacg gtttgtttga gattttggta aatttgactt tctcctatct
    16141 cccgctttgg cgcctcttta ttgactgtca tcacaccatc ttttatcgtc acaaagccta
    16201 gttcttcaaa tacttgaatc atcttgacca gcaagatttg ttgaatatta agatatgcag
    16261 ccaaatcttt cagcttgtag cgaatatcaa actctgggaa ctggtaaata gtcttgtaca
    16321 atttagcaaa ctgatctcta gtcccataac ctgtcagata ataggtcttg tcaatatcat
    16381 ttttgaaata gacagcagag aaatgctgtt cctgaaaaat ggtcttcagc tgagtaatat
    16441 cctctggaat gttttttacg acaacagctt cactagccgc aagatttggc agttctccag
    16501 gaaaatccaa gactggaaca ccttctggca agactgcatt ttttccacga atgttaaaaa
    16561 gttgaacacc ttccactcgc gcatccacca tcatcaactg gagggcagtt tggccattcc
    16621 attggttgac agacaattta accgctaact ctagattctt ggtttgagaa aactctgtcg
    16681 cccatctgcc ttgaccaaag gctaccactt caaaactcgc ctcacccttg gaaattttca
    16741 gctttagatg ggcattacct gcccccatag tacgagcact ttcgacctga aaattcttga
    16801 tataaaaaat aggtttctga ttatccattc caaaaggagc taaacgttca aaacttttga
    16861 ccgtttccaa gctaagtgcc tccaaatcca actcttcatc taggtttaac ttattcttgc
    16921 caccagcatc tgcacctttt tcacgaacat aatcttccaa aacctgagat aaatctgaga
    16981 gttgctcaac ttccagcgtc atacccgctg cacctgcatg acctccaaag gcgatgaaga
    17041 ggtctcgatg gggatccaga gcttcaaaaa tatcgaccgc ttccacacta cgagcactgc
    17101 ccttggcacg accgtcttct atattaagaa caatgactgt ctgtcccaat tcttccaata
    17161 aacgaccagc cacgattcct agaaccccag gattccagcc ttccttggcc aagacctgaa
    17221 ccttcttctc aggatccacc atggtcttgg cttcttcata gatagactga acgatttcct
    17281 tgcgctcttc gtttttctgg tgaatcataa gggcaatctc atgcgcttcc tcatcatcaa
    17341 atccagtcaa caaatcaatg gcaggattgg gatcatccaa gcgacccaag gcattcaaac
    17401 gaggagcaat ctggaaacca accgtttctt ctgttacttc gttggcagca atcccagcca
    17461 tgtccagcat ttcttgcaga ccaatgcgct gggtatgacc caacatttcc agaccatatt
    17521 gaactaagat acgattttca tccgtcagac tcaccatatc tgcaatagtt ccaatagcga
    17581 ccaaatcaag caattccact tgcacttctt ctaacagggc acaagccaac ttgaaagcaa
    17641 ctccacaacc agccaaatat ttaaaaggat aatccgcatc tggatgttca ggatggacaa
    17701 tagcataagc atctggcagg gtttcaggca tggaatgatg gtctgtcaca atgacatcta
    17761 ctcccataga ctgagccaat gcaatagcct catgaccagc aaccccattg tccaccgtca
    17821 caatcaagga aattccttct tgctcgataa agtatttata aacactagca ttagggccat
    17881 agccatcggt aaaacgattt ggcaggtaaa ctcggcactc agcaccaagt tgttccaaac
    17941 tttccttcac aatagaagcc gaagtcatgc catccgcatc atagtctcca taaacgagaa
    18001 tattttcccc ttcttcaata gcctgacgaa tccgctccac tgccttgtcc atatcatgga
    18061 gcagataagc atcatgtaag tcctccaagg aaggttctaa aaacttcttc agactttctt
    18121 ggtcctgaat ccctctctca aacaataacc gagccacctc aggacccagt ccagccttct
    18181 tggctatctt tgtaaaatcc gcatcttcta cctgcagggc aaactgccat tcataagtag
    18241 gtgttatcaa aaagacatcc actctttcta agaattctat tgcttcatta taacatgatt
    18301 tagacgtttt ctctatccag attgcttttt tataacattt tatagtatat tgaaactaga
    18361 atagtacacc tctacttcta aaatattgtt agaaatcgat ttgactgtcc cgatcgattt
    18421 ttcctgttct tatttcacta tagtgaattt tttcagatat gatttgacaa gaacattctt
    18481 ttattgcaga atcgtgttat aaaatctaac ataaaggagt tctctcatgg ttttagtaga
    18541 atttaaaaac gtcgaaaaat attacggaga ctaccacgca ctccgcaaca tcaatctccg
    18601 ttttgaaaaa ggacaagttg ttgtcctgct tggaccttct ggctctggga agtccactct
    18661 tatccgtacg atcaatggtt tagaggctgt tgacaaagga agtctcctag tcaatgggca
    18721 ccaagttgct ggtgccagcc agaaagattt ggtacctctt cgcaaggaag tcggcatggt
    18781 ttttcaacat tttaaccttt atccacacaa aacagtgtta gaaaacgtga cacttgcgcc
    18841 cattaaagtt ctaggaattg ataaaaaaga agctgaaaaa accgccaaaa aatatctgga
    18901 atttgtaaat atgtgggaca agaaagattc ctatcccgcc atgctatctg gtggacaaaa
    18961 acagcggatc gccatcgctc gtggtcttgc tatgcatccg gaactcctcc tctttgatga
    19021 accaacatct gctcttgatc ctgagactat cggagatgtt ctagcagtta tgcagaaact
    19081 ggcgcgtgat aggatgaaca tgatcatcgt tacccacgaa atgggctttg ctcgagaggt
    19141 tgcggaccgc attatcttta tggccgacgg agaagtttta gtagatacga cagatgtcga
    19201 taactttttt gacaatccaa gcgaacctcg tgcccaacaa ttcctcagca aaattatcaa
    19261 ccacgaaagt gacaaagtca aataaggagg cgcctatgaa aaaaaattct ttttatcagc
    19321 attattgatt agccttttcg gccttgctgc tgccaaacca gtccaggctg atacaagtat
    19381 cgcagacatt caaaaaagag gcgaactggt tgtcggtgtc aaacaagacg ttcccaattt
    19441 tggttacaaa gatcccaaga ccggtactta ttctggtatc gaaaccgact tggccaagat
    19501 ggtagctgat gaactcaagg tcaagattcg ctatgtgccg gttacagcac aaacccgcgg
    19561 cccccttcta gacaatgaac aggtcgatat ggatatcgcg acctttacca tcacggacga
    19621 acgcaaaaaa ctctacaact ttaccagtcc ctactacaca gacgcttctg gatttttggt
    19681 caataaatct gccaaaatca aaaagattga ggacctaaac ggcaaaacca tcggagtcgc
    19741 ccaaggttct atcacccaac gcctaattac tgaactgggt aaaaagaaag gtctgaagtt
    19801 taaattcgtc gaacttggtt cctacccaga attgattact tccctgcacg ctcatcgtat
    19861 cgatgccttt tccgttgacc gctctattct atctggctac actaataaac ggacagcact
    19921 actagatgat agtttcaagc catctgacta cggtattgtt accaagaaat caaatacaga
    19981 gctcaacgac tatcttgata acttggttac taaatggagc aaggatggta gtttgcagaa
    20041 actttatgac cgttacaagc tcaaaccatc tagtcatacc gcagattaag gaggataccc
    20101 tatgacagat ttatcatctt ggacagccta ttttcaggat tttggacaat ttttcaatgg
    20161 tttcctcttt actcttgccc tagcgattgg atcctttatc ctcgccatgg tcttaggaat
    20221 cttctttggt gccatgtcaa ccagtaaacg tccaatttta cgcattttag ctcgcatctt
    20281 tgtggaattt taccaaaata ctcctctctt ggtgcagttt gttattgttt tttatggcct
    20341 acctcttatc agtgaccata tcatcatgat tccaatttat tggacagccg ttctctgcgt
    20401 gggactctat cacggcgctt atatcgctga ggttattcgt tcagggattc agtctattcc
    20461 tagtggtcag atggaggccg ccttgtcgca aggttttacc tatatcagtg ccatgcgctt
    20521 gattaccttg cctcagacct tccgcatcat tctccctcca ttgaccaacc aaattgttaa
    20581 cctcatcaag aacacctcta ctgtagctat catctctgga gtagacttga tgtttgtgac
    20641 taagtcttgg tcggctctca acggaaacta tatcccagcc tttttaggtg ctactcttct
    20701 ctactttgcc ctatgcttcc ctgttgccca gtttggtcgc aagatggagc aagccaacaa
    20761 aaaagcctat tcactttagg aggttactat ggaatctatt ttagaagttt taaccccaga
    20821 taacctagtc tttatcttta aaggatttgg cttgaccctc tatatttctc tgattgccat
    20881 catcctctct actatcatcg gtacggtgct agctgtcatg agaaatggca aaaatcctgt
    20941 cttgcgaatc atctccagca tttatatcga atttgtgcgc aacgttccca accttctctg
    21001 gatttttact atctttttgg tgttcaaaat gaaatccaca ccagcaggta ttacagcctt
    21061 tactctcttt acatcagcag ccttggctga gattattcga ggcggtctca atgccgtaga
    21121 caagggacaa tacgaagcag gaatgtcaca aggcttcacc tcagcccaaa tcctctacta
    21181 catcattctc ccacaagcca tccgcaaaat gctaccagcc atcatttctc agtttgttac
    21241 cgtgattaag gataccagcc tcctctactc tgttatcgcc ctacaagaac tctttggagc
    21301 cagccaaatt ctcatgggcc gttatttcga accagagcag gtcttcagtc tttgcatcct
    21361 gattgccctc atctacttca gctttaacct agcaatttct agcctgtctc atatgctagc
    21421 caaacgttgg caacaagctg cagaataata ctcttcgaaa atctcttcaa accacgttag
    21481 ctctatctgc aacctcaaaa cagtgttttg agcaacttgc ggctagcttc ctagtttgct
    21541 ctttgatttt cattgagtat aaacagccac tctccagttc aattggagag ttttttgatg
    21601 agagtagata tttatagacc tcaatttgac accatacatt ttctatgata aaatgtaaca
    21661 aatttattta caacaaatcg aaatctaaat gaaatggaat tttctatgaa atcagtcaaa
    21721 ggactactct ttatcatagc tagttttatc ttgactcttt tgacttggat gaacacttct
    21781 ccccaattca tgattccagg actagcttta acaagcctat ctctgacttt tatcctagcc
    21841 actcgtctcc cactactaga aagctggttt cacagtttgg agaaggtcta caccgtccac
    21901 aaattcacag cctttctctc aatcatccta ctaatctttc ataactttag tatgggcggt
    21961 ttgtggggct ctcgcttagc tgctcaattt ggcaatcttg ccatctatat ctttgccagc
    22021 atcatccttg tcgcctattt aggcaaatac atccaatacg aagcttggcg atggattcac
    22081 cgcctggttt acctagccta tattttagga ctctttcaca tctacatgat aatgggcaat
    22141 cgtctcctta catttaatct tctaagtttt cttgttagta gctatgccct tttaggctta
    22201 ctagctggtt tttatatcat ttttctatat caaaagattt ccttccccta tctagggaaa
    22261 attacccatc tcaaacgctt aaatcacgat actagagaaa ttcaaatcca tcttagcaga
    22321 cctttcaact atcaatcagg acaatttgcc tttctaaaga ttttccaaga aggctttgaa
    22381 agtgctccgc atcccttttc tatctcagga ggtcatggtc aaactcttta ctttactgtt
    22441 aaaaattcag gcgaccatac caagaatatc tatgataatc ttcaagccgg cagcaaagta
    22501 accctagaca gagcttacgg acacatgatc atagaagaag gacgagaaaa tcaggtttgg
    22561 attgctggag gtattgggat cacccccttc atctcttaca tccgtgaaca tcctatttta
    22621 gataaacagg ttcacttcta ctatagcttc cgtggagatg aaaatgcagt ctacctagat
    22681 ttactccgta actatgctca gaaaaatcct aattttgaac tccatctaat cgacagtaca
    22741 aaagacggct atcttaattt tgaacaaaaa gaagtgcccg aacatgcaac cgtctatatg
    22801 tgtggtccta tttctatgat gaaggcactt gccaaacaga ttaagaaaca aaatccaaaa
    22861 acagagctta tttacgaagg attcaagttc aaataagtaa tcatactctc ctgggatttc
    22921 ccaggagagt tttttatagc caaatgaaat aagacaggaa cgatggaatt ttggcattca
    22981 aatcaattga taagaatgtt ttatagtgga gtgaaatagg atacgaacaa attgattagg
    23041 aaaatcaaat gaatttatag aaatctttta gcagttatgt tgtcctattc tagtttcaaa
    23101 acgctataga agcagcattg tgctagtcta gattcagttt actatactaa aacgagtagc
    23161 ttgaaatcaa aaaacccacc ctcacaggca ggttttatct gtattattca gctagattat
    23221 gctttacctt ctgaaccgaa tacgtcgata cgttcttcaa ccgatgcttg gatagctttt
    23281 acaccgtcag ccaagaattt acgtgggtcg aagagttttt tcttgtcgta ttctgcttcg
    23341 tttgcttcgt agtcacgagc aaatttacga gttgcgttag cgaatgcgat ttggcattct
    23401 gtgttaacgt taactttggc aacaccaagt ttgatagctg cttggatttg ctcatcagga
    23461 atacctgatc caccgtgcaa tacgattggg aatcctggaa gagcttctgt caatttttgc
    23521 aagtggtcaa ggtctagacc ttcccagttt actgggtaag ggccgtggat gttaccgata
    23581 ccagctgcca agaagtcgat accagtttca accattgctt tagcgtcttc gattggagcc
    23641 aattcacctt taccgatgat tccgtcttct tcaccaccga tagtaccaac ttcagcttct
    23701 actgagatac ctttagcgtg tgctttttca acaacttctt tagccaattt aaggttttct
    23761 tcaactggaa ggtgtgaacc gtcaaacatg attgaagtat aaccaacttc gatacactca
    23821 agtgcatctt cgtagtgacc gtggtcaagg tggatagcta ctggtacagt gatacccatt
    23881 gattcaacaa ggttagcgat caagttgcga gcaactttgt aaccacccat gtatttagca
    23941 gcacccattg aagtttggat caaaactgga gcttttttag cttctgctgc gcgcaagata
    24001 gcttgagtcc actcaaggtt gtttgtgtta aatccaccaa ctgcataacc gttgtcacgg
    24061 gctgcttgga caaatttttc tgctgaaacg attgccattt tatcaggcct cctgtatatt
    24121 tttatgggtc atcccattta cattgttcat tttatcactt tttgccaaaa aaatctagtt
    24181 tttcccgcag tttcgattga ttttcttcta actccatcta tgtaaaccct ttctccctag
    24241 tcttggacga cttttggaaa atctataaag aaggttaaac gattctcctc catctcgaaa
    24301 cgataagcta atttttcatg ttctaataga ctcttaacca caaagagccc cataccagac
    24361 cccttgacct tgcgactagc attgtcagaa aaagactggg ctagtttttc ttgttcctct
    24421 gagctacagc tattttcgat aaaaagttct ccttctcttt ctccaattcg aactaagcca
    24481 cctggaacag agtgcttaat ggcattgctg atgagattag aaagaatcaa cttcataact
    24541 gatgggttta gataagcctg ctgatgggtc aaactattgt ctatctggag ctctctttcc
    24601 tttgctagca aggcataatc tttgaccaga ttttgcgtca tctggaggag gtcaattgtt
    24661 tccctatcat ctcgcaattc ctgcacagaa gagagggaaa gtatctgcag aacatggtga
    24721 ttgagttcat ccacaatccc caaggcaact cccagatact ggtctctatc cttataacga
    24781 ccgatattct ctctcatatt ttcgattagg attttcaaac tagccagcgg tgttttcaat
    24841 tcatgagaag ctcctcgtag gaattcgacc ttcatcttct ccagctggag aatggcttca
    24901 ttcttttcat gcaagtccgc aataacagtc aagagatgct ggtagaggct attgatttgt
    24961 tccttgagat tacctatctc atccttagaa tccacgcgca atcgcacttg ggaatccagg
    25021 tccatcatcc gacgggtcac ccgcttgatt tccaaaatcg gtgcaacaat agtccgagcg
    25081 tagatgtagg ccaccaagag ggaaatcaga aaggaggcca gcaaggtata gggaagaaac
    25141 tggagactga tttgctccgc ttccttttgt aaatccatgg aagctagaaa ctggagaatc
    25201 atagtaccac cgtcttgcgt tttcacctcg cgctcctcaa taaagagaga ggttgtctgg
    25261 cggtctgtgt ccagaggaag actgtccttg acttctaact tgtcctcggt catctcacct
    25321 ttgacggtcc ccttgatatc actagtctgg gaatacaagt ctaacacttg ctcgatactc
    25381 tgcctatctt tcccttctag ggactgggca atggctgttg ccttttgacc aatggtttcc
    25441 tgacgatgac tcagataagt cgaaggaaaa agaaaataaa tagctaaatg aaggcagata
    25501 accagaacac taaatatcga gaaggtatag ataaatatct ttgcaaataa acctgttcgt
    25561 ttcattttcg ctccaattta taaccaacat tgcgcacagt gaggatacaa tccaagtcta
    25621 gctttttccg caattccttg atataaacat caataacacg gtcaaaggga acctcatctg
    25681 tcgctttcca gacggcatcg ataatctgag atcgagtcaa ggcccggcct tcatttttca
    25741 ctagatagtc cagaatttcc aactctttgg cattgatagg cacttcttga cctgcgaggc
    25801 ttgcactgta gctttcaaag tccaccttgg tatccttgta agaaaagatt cgtcctgtat
    25861 cgtagtagcg cttgaaaatc gcgtccaccc tcacttttaa aagggagagg gagaaaggtt
    25921 tttccagata gccatctgca aaagaggcaa aggcactcat cttgtattcc tcatcttgaa
    25981 aagctgtcaa catcaagaca ggaacctgac tggttttacg aatctcagct aggacttcta
    26041 agccgttgag cttgggcatc tggatatcca gtaaaaccag ggccacctca tagctagaaa
    26101 attgctccag agcttcctga ccgtccgctg cctcaatagt ttcatagcca caatccgtca
    26161 aataatcact gaccccctca cggatcatct cttcatcttc tacaattaaa attttcatac
    26221 tttaactgct ctctattttt tatttttctt agaataaata cctaccctat tttctattat
    26281 agtctcttgc tggccttttg tctgcaagca actgaccact agataaaacg ttgtgaaatt
    26341 cctttctcat aaattccata actttagtat attatattta agcactaaag tacaaagaaa
    26401 gcaactgaaa gcaatgattt tcaccactgc tttcggattt attttgaatt gttaaatagc
    26461 cattcctatc cactattctt gaatagaaac acaagatgca atctttattc tagactcatt
    26521 ttttcaaatt tattcaccat ccagcaagag ctcttttggt tgttttctaa ggagattgct
    26581 tgaagcaagc gccataacga gaaccactag aaccaaggca aggacaaaaa tgatgataaa
    26641 gtctgatgtc tgaatggaaa tgtctaggct cgacaaggtc ttgctaaagc catctacttc
    26701 tgcaccacca ccaaggttag aggcttgagc cgccttacta gcctgtttgg caacacctga
    26761 agtcacattg gcaaggacag tgtttccaat tgcacgggca gtgtaattag ctaggaagta
    26821 agcagaaact agagcaggga tagcaatcaa gatagattcg gtgatgaatt gacccaagat
    26881 acttgcctgc ttgaggccga tagagaggag aattcccact tccttgcgac gggcgttgat
    26941 ccaaaggctg agcaagaggg caaggaggag aactgagaag ctcaagctac cccagaagag
    27001 gaggttggcc atcttgtaca taccagagat agattgctca agagctgggt agttagagga
    27061 gctcttgacg agtgtgtagc tcttccagtt gataccactg atgccattca actctttcat
    27121 aacatcatcc aagttcttgt ctgctgttac aaagaaggtt gcgtccccat aaatggctgt
    27181 gtcttctgtg tatccataaa gttttgcagc agtgtgaatg tctgtaatag ctgtgttttc
    27241 gtaaagttct tgtgagtagg ttactgctga cttattatga ccatcaaaga gtcccttgat
    27301 tgtcacttca actgtttcct tggctccttt ttcattatct gcatcgtaga tattagagtc
    27361 cagtttaacc ttgtccccta ctttccagcc gtgtttggct gccaagtcct tgtgcaagag
    27421 gattttatcc ttgtcgtcgt tggttaagtg ctctccttcg actagtttat aagaaccaga
    27481 gacaaacttg tcttctttag aggagtcatt gacacctgta atcatcaagc tacttccaaa
    27541 acgcttggca cgatcagcag tgagattctt cttggtttct ggcgtttcaa tcaggtcata
    27601 tccagtcaaa tctccgatag cgttgatacg tttgacataa gactcaatgg ccttgttttc
    27661 ggtgattttt ttgatgtctt cacccttgat attcccagca ccacgaggcg ttccttggtt
    27721 gacgcgacga ttgatttgca tggagaagct attggtgata tttttaaagg tctcctgaga
    27781 agccttggca gtagctccct tgattgacaa gccgaccaaa ctcaagctcg ccatgaggag
    27841 aataatcagg aagatgacaa tcgatttgaa aaacttcctt gtaacatagg caaatgcgtt
    27901 gtgtaacata gattcccttt ctagattttg ttttaatcat tctattaaaa taagctcaaa
    27961 ttatttacta gtattgcgcg tttcagtcag tttcttatcc tttaattcaa gtgtaatatc
    28021 tgacgcttgt gccacttctt tactgtgagt tacgacaatc acacatttac ctgttttctg
    28081 ggcaagtgat ttgagtagtt cgacaatatc tccagcagtt ttaggatcca gatttcctgt
    28141 tggctcatca gctagaataa ctggagcttc tgagaccaaa ctgcgagcaa tggcaacacg
    28201 ttgctgttga ccacctgata actggagaac attccgcttg atctggcttt catccaaacc
    28261 aagctcaaga agtgtattct tgcttgcctt tttgttgacc aatcggatat tttccagcgg
    28321 agaaagataa tctatcaagt tataattttg aaagaccagg gaaatatggt gcatgcgatg
    28381 gtaagaatag cccttcttac gaatatcctc tccttgaaaa aggatagaac cttcaacagg
    28441 actatctaga ccagcaagta gggacaagag tgtggatttt cctgctcctg actccccaat
    28501 aatactgtaa aattttccgg gttcaaaatt ataattgatc tgatatagga ctgcttcagc
    28561 agtattctta taacggtagg taacatcttg taattgtaat aaagtcatga tttctccttc
    28621 ttaactaata gatgataaaa tttctttcgg tgattttcta aataagaata ggaaacaaag
    28681 ggctacagat aagcaactaa gcagaactag aaaaacatag gattctgcaa aagataagat
    28741 gctagttgat aaactgcttg ctttggctag tgtatcttgt aagcttgcct gatctccact
    28801 tgctagtaga gtttggagta ggtaagttgt gattgcgttt cctgcaacaa atgctggaag
    28861 caaagctcca agagatacca aaactacctc taaacagaat tgtaggaaga tcgagctctt
    28921 gccttttcca agtgcaagta aaatccccac ttcatagacc cgttctctca accagagaga
    28981 caaaaccaga attaaggctc cagctcctgc tatcaacatc ccataaagga agatggtcag
    29041 gaaggtttgg aaagttgcaa ctgagtcttt gatttgttca aaagccttgt tttccttttc
    29101 gacttggtag ccttgatttt ccaaagccaa gttttctacc tgcttcatga gtccgtccat
    29161 ttccttagga ttttctacat agaagcgtgc tgcactgact tgagcttcac tattgcccaa
    29221 aagggtttgg ctactttcat agtctgtaaa gacttgattt tcactgaagt cagaagacaa
    29281 gcctgtgaat ttctcttgtt ttttaccaga aaagatgccg ataatctcaa actctactgt
    29341 ttgtcctttt ccagattcag actgaccagc atccaagcca atcttgtcat gaagcgaaag
    29401 accgttcttc ttagccaatt cttcgtggat aaggattttc ttggaatccc ctttttgaag
    29461 gtgtcgccct tcttttagat tgaaagccga actggtaaag gttacatcct tggatgaatc
    29521 ctcaagagcc gttaagctaa ccaagttatt gtctgcagct gataaatcat cacgctccac
    29581 gctctgctcg ccagtcactg cttccttgtc ttttagtttt gcgaccgtct caagttcagg
    29641 agagacattt tccagcccct taatcttgct tacagatgct aggtctgaca acttgaatgt
    29701 ctgaccattc tctatcttct taatagaaaa agatgtattg agtgatttat aaagattgct
    29761 ttctactgtt ttgttggact tcatcagagt caaacaggct gaaattccgg ccaataagac
    29821 caataaaatc agaaataaaa taaaacttct cagtcgcttt ctgctgacat aagcccaaga
    29881 tctttggatt ggattcattt gtcacctcca tatttgtaag actattataa aacccaaata
    29941 tgaaatgttt atgaaatacg aaaaaaaaat atcgagtagg ggataatctc tagcccctct
    30001 cacaccacca tacgtgccgt tcggcatacg gcggttcaac taacttttaa cgcatgtcgt
    30061 tcaaggtaat aatccaaaca cgaaaccagt ccacgttttt caaggactgg ttttgatata
    30121 gcacgtttaa gtaccgactt ctgagctact atagtagatt gaaactagaa tagtacacct
    30181 ctacttctaa aatattgtta gaaatcgatt tgactgtcct gaacgattcg tcctattctt
    30241 atttcatttt actataattg atagtggtcg ccccagccag ataccttatc tgctatccat
    30301 ttaggaaccc ctaacttaag caatccccat aatcgtctcg atttcttctt ccattgcttc
    30361 cagataatca ctcgtaggcg agtacgcaag cgctcatcta tgctagtgac tatacttttc
    30421 atatttataa ttcattcctt tcgtttcact caaggcacaa cacagaatga aaaagtgttg
    30481 tgatctttat tttgttttat aataatagtg agaaagccta tcactactac aaatcacggg
    30541 gaggtgaata agtgagtggt acagccacta cctcgcatat tttgtcacat catttaacgg
    30601 tacataataa gttgtaccat ctgaataagt tgctacaata tcatttgcat gctctccttc
    30661 acctttagca aaggttggag ctcctgctgg atgattttta tttgcctctt tcaatttttc
    30721 aataatggca ttttttctgt atcttttata ttatcaggat ttttcactaa gattttgtct
    30781 ggatatgtcg gtttagcaga aacaattttt actgttattt cttttttatt cgaagcactt
    30841 gtccagtttc cagcattatc tttagcattt aattttacag taattcctga actaggaact
    30901 tcagtagcag gttgattatc aacattattc aactttaatt tcaaaagagc tgttgcatca
    30961 gacgttttat caatcgttat atataatgat gaattgttat tataaccagt ttcttcatat
    31021 ttagctgttt gtgagctact tgaaacagaa ctgaaattat gcccactacc tccctgatta
    31081 tcttcaatgc ttacgtctaa atgaacttcc ccactattat ttggcttagc aacaactgtt
    31141 atagtaaaat aacataaaat ttgcataaat agattaggta aatcaaagca acttctagga
    31201 atgttttagc agtcacagtg tactttccca gcatcaagcc actataactc tgcacataaa
    31261 aatggagaag atggcaatcc tcttctccaa atattaactt ctttacaaac caactatagt
    31321 tgacaaagaa cctaaaatca attgataaca caaggtcagg tcggtcaact ctttcaactg
    31381 aagccctgtc aactcttccc atttatcaat cttgtattgg agagaattgc ggtgcagata
    31441 gagttgctgg gctgttttag tgagaacagc actattttcc caaagagaga gaatgatttc
    31501 ctgaatctga tcttgatcca aaatcatctg gtgtagacat tctttaattg gcttcaagtc
    31561 cacgagtctt tctcccatac tccaaagata gagctgagaa aaagtatgaa caccttggtg
    31621 accctgacgc caccatgtct tgaacaaatc ccgctcagct ttgattaagt ctgatagggc
    31681 ttgatgtcct gtctgagacc aaacctgacc caacatgata gaaagacgaa gtccaaagtc
    31741 atactcaacc gcttcaatcg tatcacttaa aatatctctt acagaagtgt atttgtcttg
    31801 ttgaagcacg aaaacataat cctgagctcc gacctgtagc actgtctgac aattcggaaa
    31861 aagagtccgc atcatatcta gccaagaagc cagattttcc tgctgaaaat aagaaagatg
    31921 gcaataaacc aactgaatct ttttaaaaac ttgcggtgcc tgtcccttgc cttcaaccag
    31981 ataggaatac caagggttta gcgaacgagc ctgctcctgc tgggtcaaaa gggcaaccaa
    32041 ctgcttttca cgctcgctga gcccagcttc ctccagcaaa atccactgct gagaagctaa
    32101 agggagcgtg agatagccct ctttctctac tggttggtct gaaatccgag cctcaggaaa
    32161 ccagtcttgt agttcttttg ccctcatgtt ctagccctcc actttttgga tgcaccatga
    32221 aaccaaactc tcaagacgtt ccagattctc agtcatatgg agatagccca taaccgcttc
    32281 aaatcccgtg gacatacgat aagtcacgac atctgcattt ttagcctttg tgtggctatt
    32341 ggtattgcgg ccacgtttat agatttcttc ttctttttcc gttaggacct gctcctccaa
    32401 catgagagca atcaggcgag cctgagcctt ggctgacaca tacttggttg cttcttgatg
    32461 gagtttattg ggtttggtca tacctttgag gatgaggtga cggcgaatat acatagaata
    32521 caccgcatcc ccctcaaagg ctagcgcaat cccgttaatg agattgacat caatcacgtg
    32581 tccacctcac tccatctttt gtatccaata gtttaatgcc ttgagcagcc agttggtctc
    32641 ggatttggtc tgctgtctca aagtctcgat tggcacgcgc ctcttggcgt ttttgaatca
    32701 agtcttcaat ctctgcatcc aaaacttcct caacaaagac aattccaaaa atttctaaca
    32761 tatctgcaag agcttgcttg acacttgcat catagttccc tgagttgatc catttggcca
    32821 tttcaaagac aactgtgata ccgttggcag cattaaaatc ttcatccata gctgctacaa
    32881 acttatcttt aaagttttgt aactcttggg catccacgtt tcctgtaaat ggttgttcgt
    32941 aagtattctt cagatacttg agattggtct cggcatcgcg aactgccttt tccgtgaagt
    33001 tgataggctt acggtagtgc tgggtcgcaa agaagaaacg aagtacttgc ccatcaagag
    33061 ttttaagggc atcgtgtacc gtaatgaagt tacccaagga cttagacatt ttgacattgt
    33121 cgatattgac aaagccattg tgcatccagt agttagcaaa agccttgcct gttttagctt
    33181 cagattgggc aatttcattg gtgtggtgtg gaaactctag gtcagctcca ccaccgtgga
    33241 tatcaatggt atcacctaaa atctctgtcg acatgactga acactcaata tgccaacccg
    33301 gacgtccagg tccccaagga ctatcccaag aaatctcacc tggtttggaa gatttccata
    33361 gagcaaaatc tacaggattt tccttacgag ccgtttcttc atcggtacga cctgaagcac
    33421 ctagatccaa atcttccaag gttttattag ccaatttagc atagttgtgg gatttttcta
    33481 cacggaaata gacatcccct tgactctcat aggcaaagcc tttctcgatc aagtcttcca
    33541 caaaacggat gatgtctgcc ataaactcca ctacacgcgg atggcgagtc gcaggtttca
    33601 cgcctaaggc cgtcacatcc tcacgaaagg cagcgatgta cttatccgca acctcctgag
    33661 gcgtgatgcc ttcttccctg gcacggttga taatcttatc atccacatct gtaaaattgg
    33721 aaatataggc aaccttatac ccacggtact caaaatagcg acgaatcgta tcaaaagcta
    33781 ctgtcgaacg ggcgtttccc acgtggatat agttgtacac cgttggccca caaacataca
    33841 tcttgatctt gccgtcctca atcgggacaa attctcgcaa atcacgagac atggtgtcat
    33901 agattttaat cataaatcat aatcaggaaa gctgaaatcc aagaacaatt agtttcatca
    33961 ctaaaagttc aagtaaattt cagtccgaat atctctacac ttcggaatcc cttgctcctt
    34021 tctcattcag ataaaccacc tgagtctgtt tgacaaagcc aattttttca tacaaacgtt
    34081 tggcacctac attgctatct tccactgcaa tctgaaattc cttgtcattt tgctcaatta
    34141 gttggttgac gagggatttt gctaagtagc ttccatagcc ttttccacgt tcaggttcca
    34201 atattgctaa accgtagagg taattcgtat tagtcgataa atcaaccgta caagttccaa
    34261 taacctgacc agcttttaat aaaatatata gtcggctttc tggatctttc agagcttcag
    34321 cgacatatct atccacaact tctctcgatt catgttcctc tgaaaatgcc tgaaatttta
    34381 attgactaat ttgatcctga tacgaactat ctgctaacaa aatttcaaga tgggaaacat
    34441 ttgctaacgg ataaggtctt ctatccttac ctaaccaagt ttctgtctct tcatcctcga
    34501 ttagtcccca gttactggca aagtcaggat gattctctaa aaaaatacgt tctgtctgaa
    34561 aagtgactga ccgaatgggg aaagaagctg tttctctctc aaaactagta aacaatgcac
    34621 gcgcaatccc ctgacggcga tgacctggat gaaccagtat cgtcacttct acatcttggt
    34681 catctgcata gacagttaat aaaccaacaa gttcgccttt ttcataataa aggaaaaagg
    34741 cgggcatgtt tgggtcaaaa ttaagcatgt tagagagata gggatcgcga taggtaccgt
    34801 catagttttg gcaacagtta attacttttt tcgcctcaga tagctcctct tggcttaact
    34861 tgtttcttgc ttgaatcata taggtatcct ctacaaacca gacgatctgt gactggcatc
    34921 tttagcctgc tcgagtttat tgacataata ctctcgtttt tcttcgactt cgtgaatgac
    34981 aggctcatct ttcttaccat gaagacggac aatcttggcc ggaataccga caaccgtcac
    35041 gtcactaggt acatctgcta cgacaactgc tgcagcaccg accttggcat tttcaccaat
    35101 ttccacaggc ccgataactt gggcatgggc tgatatgagg gctccctttc gtacagtcgg
    35161 atggcgtttg ccacagtctt tccctgttcc cccgagagtc actccgtgat agagaagaac
    35221 gcctttttca acaatcgctg tctctccaat caccagacca gaaccatggt caataaaaac
    35281 acctgaatca atctgggctc ctggatgaat ctcaatctga gtccaaaagc gccaaaactg
    35341 actgtacata cgagctaata gtttgaagcc gtgcttccag agaaaatgcg agagacggtg
    35401 ggccgccaag gccttgacac ctggataagt cagcaaaacc tccaaagtgg tgcgggccgc
    35461 tggatcattt tcttttacaa tatcaatggt ttcgcgccac caccccatac atttctcctt
    35521 ttcttattct gaatcttttg gtgtttctgt aaattctttc ttaggtttgt aatccttgtg
    35581 atgacgtggg cggtgagggc gctcagactt ttcacctttt tcatcatgct caggttttgg
    35641 cggacgaggt agaagagcct tcatagaggc atcgatacgg cctttttcat caatcttgat
    35701 aaccttaaca tcaacttcat ccccgatttc taccaaatcc tctacacgat tggtacgagt
    35761 ccaagccatc tcagagatat gaacaagggc atctgtctta tcaaagaggt taacaaaggc
    35821 accaaatttc tcgatacgaa cgactttagc acggtaaact tcatccactt tggcttcacg
    35881 aaccaaacca gcaataattt ctttggcacg gttaatagca tcttggtcac tagagtagat
    35941 agacacattt ccttcttcgt ctatatcaat cttaacacct gtttcagcga taatcttgtc
    36001 gatggtttct ccacccttac cgatgacaat cttaatcttg tccacatcaa tcttgatcgt
    36061 atcaattttc ggagcagttg gagccaattc tagacgaact tctggaatgg ttgcttcaat
    36121 gacatcaagg atttcaaaac gcgctttctt ggcttgagca agagcctccg tcaagatttc
    36181 tgcagtaatc ccttgaatct tgatatccat ttgaagggct gtaatcccat cacgagtacc
    36241 tgcaaccttg aagtccatat ctccaaagtg atcttccaaa ccttggatat ctgtcaatac
    36301 tgtgtagtta tttccatctg agataagtcc catagcaata ccagctactg gcgccttgat
    36361 tggcacacca ccagccataa gggcaagagt tcccgcacag atagaagctt gagatgaaga
    36421 accgtttgat tccaaaactt ctgctactag acggatagcg tatgggaatt cttccaagct
    36481 tggcaagact tgagcaagag cacgctcacc aagggcaccg tgaccgattt cacgacgacc
    36541 tggcgcaccg taacgacctg tttcccctac agaatattga gggaagttat agtggtgcat
    36601 aaagcgtttc ttgtactctg gatccaaacc atcaatgatt tgagtttctc ccatcggagc
    36661 caaggtcaag actgaaagag cttgagtttg cccacgagta aagagacctg aaccatgtac
    36721 acgaggaagg aagtcaacaa ccgcatccaa aggacggatt tcatcgacct tacgaccatc
    36781 aggacgcacc ttgtcttctg taattaaacg tcgcacttct gcgtgttcca tttgttccaa
    36841 gatttcagcc acatcacgca taatacggtc aaattcttcg tggttcgcat atttttcttc
    36901 gtaaacggca gtcacttggt ctttcactgc ttgagttgca gcttcacggg ccaatttctc
    36961 ttctacttga actgcctttt ggaggtcact gttgtaggct gcaatgattt cagcttgcaa
    37021 ttcagcatcc acgtgaagca attccacttc tgctttttct ttaccgacag cagcaacgat
    37081 ttcttcttgg aaggcaatca attctttgac agcttcgtgc cctttaagaa gcgcttccaa
    37141 catgatttct tctgacaatt ctttggcacc agactctacc atgttgatag cgtgcttggt
    37201 tccagctact gtcaattcaa gaagagattg ctctgcttgt tcttgacttg ggttgatgat
    37261 gatttggcca tctacatatc ccacttgtac cccagcaatt ggtccgtcaa atggaatatc
    37321 tgaaatagac agtgccaaag atgaaccaaa catagcagcc attggtgcag atgcattttc
    37381 atcataagaa agcactgtat tgatgacttg gacttcatta cggaaacctt ccgcaaacat
    37441 aggacgaatc ggacggtcaa tcaaacgcgc tgtcaaggtc gcatctgttg aaggacgtcc
    37501 ttcacgtttc ataaagccac caggaaactt cccagccgca tacatttttt cttcgtagtt
    37561 gacttggagt gggaaaaaat ccccagttgc cattttctta gacataacgg cagcagtcaa
    37621 gacagttgac tcaccgtaac gtacgacaac agagccattt gcttgcttag caacctgacc
    37681 agtctctaca attaactcac gacccgcaaa agtcgtttga aacacttgtt ttgccatttt
    37741 aatccccttt ggattgatga aattatacgc cttgcctaca aagatcaaga taccaaggac
    37801 gtcaaaagca aagtaaaaat aggaaactga cgaagtcttc gatgaagaca agacagttta
    37861 tcttttttac acagcttttc ggccgtgttc aattactcaa gatgctaagc cgtcaagcaa
    37921 ctcaaaggaa aataggaaat cgaacgacgg agcgactgct cctaggcaga tttatctttt
    37981 tccacagagt tgtaggcgtg ttcagttttc aagatacatc attagaaagg tttaatatta
    38041 aagtatctaa acctttcacg ctaatcgcta tcgggcgatt agctaaatgc tttactaact
    38101 ctttcgtcaa ataacatcga tttgactcac tcgtgtcgtt aaatcttaca gtttaaatgc
    38161 attgtattat ttaatacctt catctttgta tcaagtacgt acagaatcta ttttatcata
    38221 tttttcttaa aaagtgaggt ctttaccatt aaaaaggaac cattcccctc acctgagaag
    38281 aatggtttgc ttttattatc ctagagactg gtgattaaac aaggcatggg ttgcttgatg
    38341 gatgtatttt gctgtatcag cattattcat cgtatagaga tgcacaccgg caacatcctg
    38401 agttaccaag tccacgattt ggtccactgc ataggcaagt cctgctgctc tgagcgactc
    38461 agggtcatgc tcatacttgt ctaagatggc tttaaatttg cgtggaagat ggatattctc
    38521 acaagtcttc aagagtcgga gagcctgatt tcgattcaga attggcataa ttcctgcatg
    38581 aatgggaaca tcaatcccag ccaagataca cttgtcctga aaatcataga agcgctcatt
    38641 gtcaaagaag agctgagtta cgaggctcga acagcctgca tccactttct tcttaagatt
    38701 ttgaatatct gaaatctgat ttggcgaatc tggatgccct tctggatagc aagctccaat
    38761 aatatcaaag tgaggggttt gttccttgat aaactcaatc aagtcggttg catagcggaa
    38821 atccttttgt ggttccacgt ctggaataat atccccacga agagccaaga ttttctgcac
    38881 cccaactttg tccaagtcag caatagtttc agcaaccttg tccttagtta gataaatagc
    38941 tggcaagtgg gcaatggtcg gaatcgccaa atcattttgg ataaagtcag ccaaacgaac
    39001 cgtcgtttcc ttgatattaa atttattatt gctggcagtt acactgataa aatggggagc
    39061 caactcctgc atatcctgca aggctgaaat aatgttatca ttacccacgg ctgggtttgg
    39121 agggaacact tcaaatgaga gtgacggtgt ttggcgtgac atatgtaata accttttcta
    39181 gttgatttct ttttgaacaa ccactgtatg gagagaaatc caatcttaca atttctcacg
    39241 cgcagcttta gctgcttcaa caaggcggat caagctttct tttgtttctg ggataccacg
    39301 tgttttcaaa ccacagtcag ggttgatcca aactttcttg cttggcactt tagcaaggat
    39361 ggcttcgatt gtgttgtcga tttcgccttc atttggtaca cgaggtgagt ggatatcgta
    39421 aaccccaggt cccacttctg tttggaagtt tttcgctttg agttcgtcca agatttcaag
    39481 gtttgaacgg ttagcttcaa aggaaataac gtctgcatcc atgttatcga tagctgggat
    39541 gatatctgta aattctgagt aacacatgtg agtgtggatt tgtgtgtctg gcgctactgt
    39601 tgagtgtacc aagcggaagg caggaatagc ccagtcaagg tagtcttcgt accagtcgct
    39661 acggcggagt ggcaattttt cacgaagagc agcctcgtcg atttggatga ttttcacacc
    39721 agcagcttca aggtcaagta cttcatcctt gatagcaagg gcgatttgga gagttgaatc
    39781 cttgatagag atgtcttcac gtgggaatga ccagttaagg atggtaacag gtccagtcaa
    39841 cataccttta acaggtttgt ttgtacgact ttgtgcatag ctagaccatt taacagtgat
    39901 agggttaaga cgagtgacat caccccagat gattggtggt tttaccccac gcataccgta
    39961 tgattgtacc catccatttt tagagaagag gtatcctgac aagttttgac cgaagtactc
    40021 aaccatgtca ttacgctcaa attcaccgtg aacaaggaca tcaaagtcaa tatcttcttg
    40081 ccacttgatc cattcgtcaa tcgtttcagc aaggaaagcg tcgtactctt tttgagacaa
    40141 ttcaccttta cggtaagcca aacgtttggc acgaacttct tttgtttgag ggaatgaacc
    40201 aatcgttgtt gttggaagag ctggaagttt gaaagcttct tcttggatag cttcacgttc
    40261 tgcaaaggct ggcaaacgag tgtagtctgc gtctgtcaag ccagcgatac gcgcacgaag
    40321 ttcagcattt tcaccaacac gctcagtcgc aaagagttct ttgttggctg caagagcttc
    40381 tgaaccttga ccatttcgga tagcatccaa gtcacggatt tcatccaatt tttcaactgc
    40441 aaaggcaaag tggttcaaga gtgctggttc aaattcttca ttagcagttg taaatggcac
    40501 atgaagaagt gagcaagagc ttgtcaaaac gatgttttca gctggaattt gctcaagaac
    40561 agccaagctc ttttcgtagt tgttgcgcca gatgttttta ccattgacaa tacctacata
    40621 gagagtcttg tcagctggga agccaccttt aacgagttca agagttttct taccttcaac
    40681 aaagtcaaga ccgatagcat ctactggtaa gtttacaagg tcagcgtata cgtcacgaac
    40741 atcaccgaaa taagtttgaa gcaagacttc aagacctttt ttgtcagcca agagtttgtt
    40801 gtaaaggttc aagaagagag ctttttcttc agctgtcaag tcttttacaa gagccgcttc
    40861 atccaattgg atgcgagtcg caccaagttc agccaattta gcaaaaactt cttggtaagc
    40921 agccactaag ctatctacga agtcgtctgc tttcacgcct tcttcaaagt ctgacaattg
    40981 aaggaaagtg aagggaccta caagaacagg acgagtgttc aatccaagtt ctttggcttc
    41041 ttggaactca tcgaaaatct tgtgaccagc caattttact tgagtgtctt tttcaaattt
    41101 aggaacgatg tagtggtagt tagtgttgaa ccatttcttc attggaaggg cgcgaacgtc
    41161 ccctttttct ccctggtaac cacgtcccaa agcgaagtag cgctcaaggt cagacaagtc
    41221 caagttttga acggatgcag gcaccacgtt gaaaaggaaa gccgcatcta ggaagttatc
    41281 atagtgagaa aagtcatttg atggaatttc agtgatgcct ttttctttga caatgttcca
    41341 gtgtttagca cgcaagtctt ttgctgctgc taaaagttct tcttctgaga tttcttttct
    41401 aaagtatttt tcagttgtaa attttaattc acggaattcg cccaaacgag ggaaaccgat
    41461 gattgtagtt gacatgatgt gtcctccaaa atttgttgtt gaaactatct taacagaaaa
    41521 gaaagcgtct gtataattgt aaaaaattag ggtttgatat agtttgaaac tatatatctg
    41581 tttcggacaa aagaaaaaga cttgaagcaa acgtctcaaa tcctttgtaa ttcttacttt
    41641 acagctatat tccaattaga atactaaaac atgttattag taattcttat aagtgactat
    41701 gacctgttat tagaaaagac tataactgat tctagtcaac tttttccctg ttcaagtggg
    41761 acgattgcta gtgtctttcc taaactggct aggactttta agactgtatc caactgagga
    41821 ctagtctttc ctgtctccat cctagctatg acaggctggc ttattccact gacttcttcc
    41881 agctttttct gactgattcc ttgttcatac ctagcctcaa tcaactcgct catgatagcc
    41941 actcgcatat cactttcaag gatttcctcc ttgctaaaga gctcagatgg acatccttcc
    42001 aattactccc aatagcacta ttcttcatca cttaaccctc ttttttttac gtctatgtat
    42061 ttttaaaaaa atgagcgaat tatgattcga tagattgacc agtgggttta aagttggtgc
    42121 tagcctattt cttaagcgat tttccttttc taggataaag cagttcctgc ttgcttaacc
    42181 ccaattttcc acgatgaatc caatagtaaa tggttgaaat tcccacgtta acccctttag
    42241 ccatcaccat catttcaggc gaaaattttt ggttatgttt ttggttatgt atagtggaga
    42301 atcttttcct ttagtttctt aagactgttg agcgtagtcg gcagaataaa tctctttgaa
    42361 gcgccctttt ccaagacatt gtcggactgt cccacgcttg atttcagtgt ggatagtttg
    42421 aggagctttt ccaagtagag aggcaatttc tctatttgat tttccttctt ttttccatcg
    42481 ttcgattaag cgacggctat cgattgtcaa atgtttgcct tttgtagtat aattgtcttg
    42541 catttctgtg ccttttaatc atttcaatct taaattggac tttttttact tgggttgtac
    42601 ttaatctatg aggaagacaa gaaaaagaat atcaatcaag taaagtcaca aagtcacatt
    42661 agctccgagc aaccattgca aattgaggta ctcacacaat gattaaaaca tttctctctg
    42721 ccctttcggt cattctcttt tctatcccta tcataactta ttcttttttc ccatcttcta
    42781 atcttaacat ttggctatct acccaaccta tcttggcaca gatttatgcc ttccccttag
    42841 ctactgcaac tatggctgct attttaagtt tcttattttt tttcctatct ttttacaaga
    42901 aaaataaaca aatacggttt tactctggca ttttgctctt actatcgctc atattactat
    42961 tattcggaac agataaaacc ctttcttctg catcaaataa gactaaaacc ttaaaattag
    43021 taacttggaa cgtcgctaat caaatagaag cacaacatat tgagcgaatt tttagccatt
    43081 ttgacgccga tatggctata ttccctgaac tagctaccaa tatcagaggt gagcaagaaa
    43141 accagagaat caaactattg tttcatcaag ttggactttc tatggccaac tatgatattt
    43201 tcacttctcc acctaccaat agtggaatag ctcctgtgac tgtgattgtc aagaaaagtt
    43261 atggtttcta tacagaagct aaaacttttc atacaacacg gttcgggaca attgtattac
    43321 attcgagaaa acaaaatata ccagatatca ttgccttgca tactgctcct cctctgccag
    43381 gtttaatgga aatctggaag caagacttaa acatcattca taatcaattg gcttcaaaat
    43441 atccaaaggc tattattgca ggtgatttta atgcaactat gcgtcatgga gcacttgcaa
    43501 aaataagctc tcatagggac gcattaaatg cactgccacc ttttgaaaga ggaacttgga
    43561 atagccaaag tccaaaactt tttaatgcaa caatagatca tattttattg cctaaaaacc
    43621 actactatgt taaagattta gacattgtaa gttttcaaaa ctctgatcat agatgtattt
    43681 ttacagaaat cacattttaa ttattttata taaaatcacc cctctaatgt tcataaacta
    43741 gagggggaat ttgtatccta ctatcgttta acgcacttct gcattcactt tttcttcgag
    43801 agacgcttgg attttttcca tatagcgtgc gacttcttcg tccgttaagc tgtcttctgg
    43861 attttggaag gtcaagctat aagccattga cttcatacca agtcccagtt tttcacctga
    43921 gaagacgtca aagagtttga tatctgtcaa acgtttcacg ccggcagctt ggatagcatc
    43981 tacaacttct tggtgagtca cttctgcctt gaggagaagg gcaacgtcac ggctgactgc
    44041 tgggaatttg gtgatttcca caaatggaac agcaggttgg agcgcccctt cgatggctga
    44101 aaggttaagc tcagctacat acgtttctgg aatatcgtaa gccttggcag tgactggatg
    44161 cacttggcca aggaaaccaa gaacttggtc accgagtgaa atcacggctg tacgacctgg
    44221 atgaaggcta acgatttcag atgttgctgt ataggttact tggagtccca aacgagtaaa
    44281 tagggcttca aggattccct tagcatagaa gaaatcaact ggaactgctg ctgtttggaa
    44341 atctttttca gcaaccaagc ctgtcaaggc aaaggcaaag ctgttgatct catttggaag
    44401 ttcttctttt ggattacctg tttgttcaaa gacttttcca atctcataaa gggccaagtt
    44461 tttattctta cgagccacgt tgtaggcaac ggtatcaagg atccctgaaa tcatattttg
    44521 acggaggact gaacgatcca cagtcattgg ccacatgagt tcagtaaggt tacttggttg
    44581 agctgtgaac tcaactgctt tttcaggagt tgtcagagca taggtgatga tttctgtcaa
    44641 acctgctcct tcagcaatgg tacgaacttg acggcggagt ttttgtatca cagtcaattc
    44701 accagctgta ccatcgtctt ttggaaggct ggttggcaag cggtcatatc catagatacg
    44761 agcgatttct tcaaagagat cagcttcgat tgtgatatcc caacgacgac gtggtacgct
    44821 gactgtaaag ctgtctgcat ttccagaaag accaaagcca agacgacgga agacgtcttc
    44881 tacatcagca taagacagct cagttccgag gacacggtta acatcagcaa gggttgaaga
    44941 aacttccaca tcagaggtat caagctcacc cgctgaaacg atacccttac gcaccgtcgc
    45001 gcctgcaagc tctgcaatca tgctagctgc cgcatcaagg gcttcattaa ctgttgccac
    45061 attaattcct ttttcaaagc gagaagatga ctcagaacga aggttcaggc gaccacttgt
    45121 cttacggata gatttgccat taaaaacagc agcttcaagg ataacacgac tagatttttc
    45181 agaaatttct gtagcctgac cacccataac accggcaagg gctactggtt tgtcagcaac
    45241 tgtaatcacg aggtctgtct cagccaagtc tcgttcttca ccgtccaggg tcactaattt
    45301 ttcaccatca cgcgcttcac gcacacggat gtcagtccct tcaaatgtgt ccaagtcaaa
    45361 agcatgcata ggttgaccaa agtagagcag gatgtagttt gtcacgtcta caacgttatt
    45421 gatgggacgg atgccttcgt tcatgagaag gttttgcaac cattgtggac ttggtgcgat
    45481 agtcacattg tccaagatac gagctgcata gtaaggcgcc ttgtctgtct caatgctgac
    45541 agaaagggca tctgccgcag cttcattagt ttctgttaga gtaaattttt taaagttgac
    45601 tgccttgtca tagatggctg ccacttcgtg agccactcca cacatagaaa gggcatctgc
    45661 acggtttggt gtgatggaaa gttcgatgat ttcatcatcc aagtctaggt aagaaaagac
    45721 ttcctcacct ggcacggcat cttcaggcaa gatttggatg ccatctgcga attccttagg
    45781 cacaactgag tcagaaattc ccaattcacc aagtgaacag atcattccaa gtgactccaa
    45841 accacggatt tttccttttt tgattttgta gttatcagcg atacgagctc ctggaagagc
    45901 caccatgacc ttgatcccag cacgcacatt tggggcacca caaacgatct gacgctcttc
    45961 ttcttcgcca acgttaatct gacaaacatg gaggtgagtc tctggcacat cttcgcaaga
    46021 caagacctca ccgacgacaa tttttgagag accagcagct ggtgattcga caccctctac
    46081 ctcgatccct gtagttgaca ttttttcagc caactcttgt gatggcacat caatgtccac
    46141 caattctttt aaccatttat aagatacaag cataatttag ttctccagaa tgacagttgt
    46201 cactctagtt cttttccttt cctatcattt caatagaaga atcctcttct taccttaatt
    46261 tctttctcag taaccaatcc gtatctactt tttgaccaac cataaaatga tgttggctaa
    46321 atttttcaaa accatatcgg ttataaaacg cttgagcttt tgtattatgc tcccaaacac
    46381 ctagccaagc ccaagaaaaa ctattttttg tagcaagttc aagtgcgaat tcaaacagtt
    46441 gcttacctag tccaaatcct tggaattttt gtagcacata gaggcgttga atttcaaaag
    46501 cgtcctctaa ttctctctca gtttgagcac ttccccagtt gactttgaga aaaccagcta
    46561 tctcctcctc atgcataatg aaataggttt cagagtcagg atttcccaac tcagttgaca
    46621 aagttttcag actataagcc tcttcaaagt attcctgtaa ctgctcttcc gtattatcat
    46681 acgcaaaggt ttcacgaaag gtttgtttgg caattttagc caacacctca acatctgcca
    46741 tttctacttt tctaatcatt atttaaactg ttctgagaag cggacatctc cttggtagaa
    46801 tccacggata tcgttgattc cataacggag catagctaca cgctcttgtc caagaccaaa
    46861 ggcaaagcca gagtatacag tcgcatcgat accactcatt tcaaggacac gtgggtgaac
    46921 cataccggcc cccataattt cgatccaacc tgttttctta catacattac agccttctcc
    46981 accacacttg aagcaagaaa catccacctc aacagatggc tctgtgaatg ggaagtaaga
    47041 tggacgcaaa cgaatttgac gctcttcacc aaacattttt tggacaatca actgaagcgt
    47101 tccttgaaga tcagccatag agatattttt cccaactacc aagccttcga tttggtggaa
    47161 ttggtgactg tgggtcgcat cgtccgtatc gcgacggaag acacgccctg gcgagatcat
    47221 cttcaaagga cctttagaaa aatcatgggc atccatagca cgcgcctgaa ctggagacgt
    47281 gtgggtacgg agcaagattt cttcagtgat atagaaagta tcctgcatat cacgagctgg
    47341 gtggtctttt ggaaggttca tacgttcaaa gttatagtag tcttgctcca cttcaaaacc
    47401 atccacgact tgataaccca taccgatgaa gatatcttcg atttcttcac tggtttgtgt
    47461 caaaacgtga cggtgaccag tcgcaactgg acgacctgga agcgtcacat ctatactctc
    47521 gctagccagt tgagccgcga ctttcttttc ttccaagagc ttagctgttt cttcaaaagc
    47581 agcagtcaag acatcacgag cttcattgac gtgtttcccg atgattggac gcatctcagc
    47641 agaaacatct ttcatccctt tgaggatttc agtgagcgaa ccctttttac caaggacaga
    47701 gacacgcaaa tcttgcatct ctttttcatt tccagcagta atctgcttca agctagccag
    47761 cgtttcttcg cgaagcgctt ttaattgttc ttcaatagtt gacatatttc ctccatcagt
    47821 ctctcgtaga taaaaagaaa accacatgcc aaaaactcca ctcggagcgt tgacacgcgg
    47881 taccatccgt tttcatctga caagtcagac cttcatttct aaatccatgc gcaagtgaat
    47941 tcacccagct ttcatataga gagcttgcag tcacggctct cctccctgat atacttccct
    48001 tgggctacta gtctttcaga ttcctattca attactactt agtttatcag atttttacca
    48061 ttcttgcaag acctatctta cttctgcttg ttagcttatt cttatctaaa tttatataaa
    48121 caatttatct aaattaacta tttataattt ttgtaacaaa attaaattaa ttgacactcc
    48181 cctataaaat aaagaagttt agaatttaat gtcttccaaa cttctttatt ccatatttaa
    48241 tgaaatgcca ccttaaccgt gataatagct agtcatcaat aaaaaactat ttgaataagg
    48301 attctccatt tgattcaatc acttctttat accaagtaaa agacattttc ttatatcgat
    48361 ttaatgtacc acttccatca tcgtttcgat caacataaat gagaccgtac cttttagaaa
    48421 gttgtgcagt ggacatagaa acacagtcaa tacatcccca agacgtatag cccataattt
    48481 caacaccatc ctgtagagct tcagcaactt gcaataaatg ttctttcata tactgaattc
    48541 tataatcatc ttggacggtt aagttattaa gttcatcttt tattagttga tctttagcac
    48601 ctaatccatt ttctactata aataatggga tttgataacg gtcataatat ctatttaaaa
    48661 ttatacgtag tccaattgga tcaatttgcc atccccactc tgaagactct aaataaggat
    48721 ttactaaacc accaataata ttcccttctc ctgaattata ctgtgttgga agagcagatt
    48781 gagtcacact catgtaatag ctaaaggata aaaaatctac ggtataattt tttaataact
    48841 ctgcatcttc agctgcaaac tctatgttaa tgtcattttc cttaaaatat ctttttgcat
    48901 aattcggata ataacctcta acatgcacat ctgaaaatag ataatttaga ttctcatact
    48961 catgagtcgc ccatacatct tttggatttg gagtcattgg ataagctggc atagctaata
    49021 ccatacatcc caccttaaac tctgaattaa tctcacgagc aatttttgta accaaacttg
    49081 aggcgactaa ttcatgatgt atagcttgat ataattcttg tttcgaaaga ttctccttag
    49141 gtatatctat tcctccacta gtaaatggta attccaaaac agagtttact tcgttaaatg
    49201 taagccaata tttaacttta tctttatacc tttctaaaac tgttcgagca aatttttcat
    49261 aaaaatgaat cattctccta tcaacccatc catgatattt tcttgctaaa tataatggag
    49321 tctcatagtg tgaaagagtt acaagtggtt ctatcccgtg agcatgtagt tcatcaaaca
    49381 attcatcata atatttcaac ccagcttcgt taggttcttc ctcatctcct tttggaaaaa
    49441 ttctactcca tgcaatagaa gtacgaaaaa cattaaagcc catttcagaa aacaaggata
    49501 tatcttcctt atatttatga taaaaatcaa tacctatcaa ttttaagtta tcttctgtag
    49561 gattttctgt tgcttctcct aatccacctt tgggtaacac atcctgaact gataagccct
    49621 taccatcttc attatatgct ccctctactt gattagctgc aacagctcca ccccaaagaa
    49681 aatcatctgg aaaaatggtc ataactttcc tccattataa tattaccagt aattccttag
    49741 aatgctcgat tgtctgatta ttaggtaata ctaatacatc tagaaaatca ttggtattcg
    49801 ttacaattac tggtgtaact gtttcgtagc ctttagtctt gattaaattc aagtccattt
    49861 caaaaatcaa ctgatttttg aaaactctgt ctccttcttc tacatgacta ataaaacctt
    49921 gaccttttag ctcaacagta tctaatccaa tatgaattag taactcaaca ccctcatcac
    49981 tcttcaatcc aattgcgtgc ttagtcggaa aaatatttgt aattttccca tcaaatggtg
    50041 cataaacctt accttcactt gggataatcg ctactccgtc tccaattagt ttatctgaaa
    50101 atgttttatc ctggacatcg cttaacggaa tgatttctcc tgatatagga gaaaatatca
    50161 tttttttatt tgaaactcca gcttcaactt ctaaattgct agaactctct tcttcatcga
    50221 ttccaaatat ataagctaat acaaaggtaa taacaaccga aatgaccgcc acaattaaag
    50281 catttacaat atttgatggc acatcagaat aaataaattg aggcaacgct atcaaagatg
    50341 ggacagcaaa tagatatgct ttaacactag taagacctgc aaataatccc gctaatccac
    50401 caccaatcat agctgcataa agcggttttt tatattttaa agtcacacca tataatgcag
    50461 gttcggtaat ccctgcaagt aaggctgaga aacctgctgc aaaagcaatt tgttttgtat
    50521 tattattttt actctttaat gcaacagcca tcgaagcagc cccttgagct aagtttgacc
    50581 ctaacattgc tggaagaatt aatacgtctg gagtagcaat agatgccgcc aaaaaaatag
    50641 gtgcaaaagc ccaatgcatt ccagtcataa caataaatgg cataatagca ccaagaatag
    50701 ctaatgtaag ccatccagct acaccataca tttgcccaac tagatttgat aatccttcac
    50761 caacaattac tccaataggt ccgactacaa ctaaggcaat acagcttgat actaataata
    50821 ctagcgtagg ttgcaaaaaa ctcttagtaa tagctagtgt taatttagca attatttttt
    50881 caatatattt catcaaccaa accataataa gaattggaac gactgatgaa ccataactag
    50941 ctggtgtcac aggtgcacca aataaactaa gaggattccc tgattgcacc atttgaacaa
    51001 aatttggatg gagaagtaca cctgctacag acatagctaa tgtagatgtt acttttaatt
    51061 tttgtgatgc agaataagct aataacagcg gtaagaaata atatggagca tccccaaaaa
    51121 atgtcaaaaa agcaatagtc tgagaatctg attgcaatat accaagcatt ggtaaaatga
    51181 ttaccaagac tttcaacata cctcccccta acattgctgg aatgattgga gtcatggaac
    51241 cagcgatata ctcaatgatt ctttctaaaa tattcccttt gtgcccttga acaactgaat
    51301 cggattcaaa attgccaagt ttaacgaatt ctttataata attagctaca tcattaccaa
    51361 gtataatttg atattgtcca ttctttttca taatacctat tacacctggt atcttcttca
    51421 catcatcatc attgactaaa ttttcatctt ttaattctaa tcttaaacgt gttacacaat
    51481 gggtaactct attgacattt ttttcacctc caattacatc gaggattttt tgtaccgtat
    51541 ctttataact catggtattc tcctattcta ttaatctaaa ttttttgtta agcgacgaat
    51601 atgagccatc aaataagcta attcactaga agtcagcaaa taattgtact ccgtttgtat
    51661 aaacattgct acctgttcac cacattcata ttctctagga tatttatttt tcattaatgc
    51721 taacaagtct tcatcatcat cgtcacaata agttgtattt tcaaccaagc gatgggcaaa
    51781 taattttata tgagttatga atctataata atcaatagaa tcttggttaa actcagtaca
    51841 atagaaatct tgaatgattt tctcaattcc cataattatt tcagtgattt tatacgactc
    51901 ttgaaaatta ttttctaaat tagcattaac aaaatgtagc gctatgaatg cagcttcgtc
    51961 aattggaagt tcaataccta actctttttt tattatttgt aaagcccttt tcccaagttc
    52021 aaattcttct ttataatatt tcgatatttc ccagcgtagg ggattcgaaa taataatccc
    52081 ttctttataa cgttctatgc tcgaagaaat atgatccgtt aaattaatat agataatttc
    52141 atcaaaatta ttacccaatg ttattttacc taggttaatt attttttcgg tgatgtacac
    52201 caactccaaa ggaacgttaa taaacatctc tgtaaaacgg gtcatattat ctctattttt
    52261 gagaaaaaaa cttttctcaa tatcaattgg atttacttta tctccagttt ttcttccaaa
    52321 agctattccc cttccaaaaa gaagaatatc gatatctttt ttactttgcg caattacggc
    52381 attgtggttt agtattcgtt ttatgatcat aaaatttccc ttttaaaata aaaggaacct
    52441 acttaaaaac atcaagaaac ttcttctgat gtgattaaat aggttcctgc tcacttgtat
    52501 tagtgataac atccttttat ttcaattttt aatggtgaca tgaagcttaa ataattaata
    52561 actctgtaac cgtttttatt ttatgatatt tcaatctatt tgtcaagtac ttataaaaat
    52621 ttttttattt tgtgtgattc gaatgtgata atggcaacag tctcactaaa gaaatgaaaa
    52681 tcatacatag aaatttttaa aaattttctc tatcgtaaac ctgccactag ttcagaaact
    52741 atactagctg attccaaacg taatatggtc atctcatcta ccttccctaa taatggcatt
    52801 gcaccatacc aaacaatagt cttattcacc aaaagaatag gcgttactat ttttgattga
    52861 gtaaaagaca ctttaatttt ctggctcttc aactggtcta gccatgcttt atttgcaacc
    52921 gtctctggta tacatatctc aatttgacta atcctaaatt cttttagaaa attcatcagt
    52981 tttgtctggt gcacataagg taaaataagc agacattcct gtctttcccc tgctaagtcc
    53041 tctctcaaca ccttctcata tctactatca acataaacga attgtttctc ctcaccctca
    53101 atggcacgat aatccatctt tcgataagct acttgtcgtt tctgaaacat cttttctaaa
    53161 taaggaacat gaatatccac ataatcgaaa atacgcacca aagacttatc cttgtagttt
    53221 ctatgaatcc aacctgcata ctgaatcaaa ttatttttcc aagaaaaggg tgctgccaag
    53281 ataagcgtgt ccaactgagg taagtcaaaa ccttcgccaa tgtattttcc agtagacaac
    53341 aaaacaaacc ctttatctaa ctgttctaac gtctccagta aactcgttct ctctcggact
    53401 ttggtttttc cgctaataat gtaacagtca tcaacctctt tctctttcaa taatttttca
    53461 aagacatcta tctgttgaat tcgattaact aaaaccaaga tattccgtcc ttctgccact
    53521 tgggctagaa tatccttgag aatcatctga ttcctcactg agtcagtagc aatccaatca
    53581 ctaagctgta taaaattact tgctttggtc ttttcaattt ccaaatgacc aaaagaagtg
    53641 aatcttaatt gcaattgccg tttaaaatcc gtttccctct tatcagcagt atggagtatc
    53701 tcaccaattc tctgaaaaac aataggctca tgaccattct tacgctcagg cgtagccgtc
    53761 aaaccgtaaa gatacttccc tctaaactga gcaacaactt tttcaaacat caaggcagag
    53821 acatgatgac actcatccac aatcatcatc tcatactcat ccaaaagact ttgactattt
    53881 tccaacttaa atagagattg aatcataacg acatcaacca gtttactcag ccatttctta
    53941 gtcccaccgt actgcccaac atagccgatt accttttcac gacctgatgc cgtataacgg
    54001 atagcctcct cctcttcgaa agtcaaaaag cagtttaagc aatctagcca ttggtctaag
    54061 agttgcttat tatggactag aataattgtt tttgttttcc gttcagagat aagagcagca
    54121 cctaaaacgg tcttcccaaa accagtctcc gcatgaagta aaccattttc tttagaagtc
    54181 atatctgaca gggctaactc ttgctcaaaa gtgagttctc ccttaaattc cacgctaata
    54241 gacctttgta cctttctcct atcttccaca gatacctgct taaatttatc ttgcaatgga
    54301 tacagcaaac ctcttggcaa ccataaataa tgatcggatt ctccaaataa atacattctc
    54361 tcaggaattt gataggttgg ctgtcgcata gcctgcttta aatatagtaa aatgaaataa
    54421 taacaggaca aatcgatcag gaaagtcaaa tcgatttcta acaatgtttt agaagcagag
    54481 gtgtactatt ctagtttcaa tctactataa aattcgggat tagaaaagga agccatattt
    54541 ttcaagaaaa aagtgccttg gatgtcacag acgatttttc aagttggatc atattggata
    54601 aaacgacctt caactcctta tccaattctt gcttgcctaa ctcctcttgg attaacagtg
    54661 ccactttagc agttgaaatc ctctgaattt cttgtagata cctccattgg tcttcataag
    54721 gctgaaactg ttcatccaca aagaccgttc gcccttgatg gtaagcttct ccttgaaaag
    54781 gcaaggcaat caaatttcca aatcccccct taggaaggac atcctgattt ggaaacatgc
    54841 gatcaaaaga atcaaaggac agttgcatac tttcctgcat tgccaattct aatagtttct
    54901 ttccaaacag gcgagccttt cgactcagaa tcgcttcctc aaagaagaac caaatatgga
    54961 gtccgtaacc cgaacgagaa atctctaaat gggcttccat ctggcgttcc ctggctattc
    55021 ttcgaatggt taaaccagct tctttccaat ctccttcatc caaatccagt accaaaaaat
    55081 aacagctatc atctaagtgc ataggaaaga taccgatagc tgcctcccca cgaaaatgag
    55141 atttcaaaac ggaatccgtc aatgtctgga aactccgttt ttcaggtagc aactgcttcc
    55201 aaccataatc ataggaagga aaatactgaa ttttcccttg atcattgata aaactcttag
    55261 cataaacatc ataacggcca gcaaacacag aggtaaacaa ttgtaatttt tcttgcgtcg
    55321 tcaagcgact actttgaagt tggaacatct cctcgaactg agagcgttcc ataacaaact
    55381 gactcttgtc tttaagacgt ttacacaaga aaaactcact atccccatca aaagaagaaa
    55441 agacatcaag tacttctacc acaattccat ccaaagacac aaaaacagcc ataagagtca
    55501 cctccttgat tcctataggc tgattataac aagaatagct gaaattgtac acgaaaataa
    55561 aatcccttat ttgttacaat acctttgaaa acttttattt ctttgctacc cagccgatgg
    55621 catcgcttgg gggattttcg gtatcaatcc agataaattc aataccgatt tccccatttt
    55681 taaatttagt taaacgaata ccgttgattt ccagttcatt gagtcgttga cctgtcaaga
    55741 cttctcgttc tttcaactgg aaaagttaag gggggaacta atacaaatct tctaagcttc
    55801 tatattcaat gatttcattt ttgataatat tctttttaaa ctcaaaatgt tttaaaggat
    55861 tatcgattaa cactaacttt ggaatatcat ctagatttgt gaccaaggat aaaataaaat
    55921 ccgattgaaa ctccttgact ttttcaaatt cttttgcagt taaacgcaca cgccccttag
    55981 attttcggat accttttact tcggcaaggt aagaatactc ttggacatct acctgaaagt
    56041 catatccatc accataaaga cgggcatcgg ttaactgtcc accttggaat ttttcttctt
    56101 tatcaaaatg aaggataaaa taattctcag cctccattcc cgtttcctgt agacgtttga
    56161 atttagttcg aactattggt ttttcaacga tggttatgcc tgttttcttc ccttcactgg
    56221 caagtaacat tttaactatt tcagcataac tatgaacatc ttcatttcca aacatcatat
    56281 caattaaatc tttacgaaaa cgataaactt cagctttctg ccaccaacct tttcgattat
    56341 tgtcaaaata aggatcaaat aaatccattc tattttttac aactccagtt gtttcagcaa
    56401 ttcccagaga aaccacataa cgataaaact ccgacttgct agagcattga aattctttta
    56461 taaaaagctt gtcaaacttg gcaagaccgt agccaattaa atttaacaat tcataatgag
    56521 ggtgtttgga catcactttc tccatcaata gatattgatt tcattatacc aaaaaaacac
    56581 ggctcatcac cgtgtttctg tgtttattta acgagtttct tcatctcatc aatacgtgct
    56641 acggtcgcat catacttggc ttggtagtca gcttgtttgt cgcgttcttt ttggacgact
    56701 tctggtttgg cgttggctac gaagcgttcg ttagagagtt tcttaccaac catgtccagt
    56761 tctttttgcc atttagcgag ttctttgtcg agacgatcta gttcttcttc aacattgagg
    56821 agatcggcca gtggcaggta gatttctgct cctgtgatga cacttgacat agccagttca
    56881 ggtgcaggga tggttgatgc gatttccaaa tgttctggat ttgtaaagcg tttgatgtag
    56941 ttgacattgc tgttaaagaa ggcttccaag tcactatcgc tagtcttaac aaggattgta
    57001 ataggtttgc ttggtgctac atttacttcc gcacgcgcat tacgaacggc acggatcaag
    57061 tctttgagac tttctacacc agtgtgagcc gcaaggtctt caaaggctag attaacagtt
    57121 gggtatgcag ctgtcacgat agaaccttct gagatttgtc caaagatttc ctctgtcacg
    57181 aatggcatga ttgggtgaag gagacgaagg atcttgtcca gagtgtaaag gagaacagat
    57241 cgagtaatta ccttatcttc ttcattatcg ctataaagga cttccttggt caactcaaca
    57301 taccagtccg caaattcatc ccagatgaag ttgtagagga tgtggccagc aacaccaaac
    57361 tcaaacttat caaagttagc agttgctttt ccaatcgttt cattgaggtt gtggagaatc
    57421 cagcggtccg tcacattacc agcctcacct gttgcaactt ttgtgacatt gtcatgcgcc
    57481 acatccagcg tcaaacctcc attgttcatg aggatatagc gagaaatgtt ccaaatcttg
    57541 ttaataaagt tccatgaagc atccattttc tcataagaga aacgcacgtc ttgtcctggc
    57601 gcagaaccgt ttgaaaggaa ccatcgaagg gcatcggcac cgtatttctc gataacatcc
    57661 attgggtcaa tcccgttacc gagagactta gacatcttgc gtccttgctc gtcacgaata
    57721 agaccgtgga taaggacgtt ttggaatggt tgacggcctg tgaattccaa tgactggaag
    57781 atcatacgag acacccagaa gaagatgatg tcgtaacctg ttaccaaggt tgaagttggg
    57841 aaataacgtt taaagtcttc tgagtcgact tcaggccagc ccatggttga aaatggccag
    57901 agggcagaac tgaaccaagt atccaagacg tcttcgtcct gagtccatcc gtcaccttct
    57961 ggagcttctt cgccgacata catttcacca tcagcattgt accaggcagg gatttggtga
    58021 ccccaccaaa gctgacgaga gataacccag tcgtggacat tttccatcca ttgaaggaag
    58081 gtatcgttga aacgaggtgg gtagaattcg accttgtcct ctgtgtcttg gttggcaatg
    58141 gcgttcttag ccaattggtc catcttgacg aaccattgag tagacaagcg tggctcaact
    58201 acgacacctg tacgttctga gtgaccaaca ctgtggacac gtttttcgat tttgacaagg
    58261 gcaccgattt cttccaactt agcaacgact gccttacgag cttcaaaacg atccatgcct
    58321 gaaaattcaa aggcaagctc attcatagtt ccgtcgtcgt tcatgacgtt gacttgtggc
    58381 aagttatgac gttggccaac caagaagtca tttggatcgt gggcaggtgt gattttcacg
    58441 acaccagtac caaactcagg atctgcgtgc tcatctccaa cgattgggat gagtttatta
    58501 gcgattggaa ggatgacgtt tttaccaatc aagtccttgt agcgcgggtc ttctggatta
    58561 accgcaaccg caacgtcccc aaacatagtc tcaggacgag ttgtagcaac ttcaagggcg
    58621 cgtgaaccat cttccagcat gtaattcatg tggtagaagg caccttccac atccttgtga
    58681 atcacctcaa tatcagaaag ggctgtgcga gctgctgggt cccagttgat gataaactca
    58741 ccacggtaga tccagccttt cttgtaaagg ttcacaaaga ccttacgaac agcttttgac
    58801 aaaccttcgt caagagtgaa acgctcacga gaatagtcta cagagagccc catcttgccc
    58861 cattgttcct tgatggtagt ggcatattcg tctttccatt cccagacttt cgtcaagaaa
    58921 gactcacgac caaggtcata gcgggaaatg ccctcaccac gcaagcgctc ctcaacctta
    58981 gcctgagtgg caatccctgc gtggtccatc ccaggaagcc aaagggtatc aaaaccttgc
    59041 atgcgttttt gacggatgat aatatcttgc aaagttgtat cccaagcgtg accaaggtga
    59101 agtttacctg taacgtttgg tggtggaata acgattgaat aaggcttagc cttttgatcg
    59161 cctgaaggct tgaaaacatc ggcatcaagc catttttggt aacgaccagc ctcaacctcg
    59221 gctggattgt atttagatga aagttcttta gacatgtgtg ttctccttaa ttacttttat
    59281 tgacaatttt aaccaaacca atttttgaaa gttcaatata aatctcttca atttcagcaa
    59341 atgctgcaag tggtgacata gtataatttc caggattata tttaagatca tacttgctta
    59401 tctttgaaat ataataccta gagtgtttca attttaatga ttccaacttt gatttaatat
    59461 ctactaatgt attatggttt aactttaaaa acaacttatt ataattacca tagagctctg
    59521 taagagcatt aaagtattct ttcactagag ctatagcgtc aatcttagat gtttcttggt
    59581 ttagttttat caactcccct ttcaattttt tccatttaaa gttggaattt aaaagataat
    59641 ctaaatcaat atagaaatct attataacag tctcatcatc tgggctaaca gcttttacct
    59701 catttattgg taagtcagta tgttgcgaat aatttctcaa agaatggcaa aatcgataag
    59761 caaaattggt atcatactga tagcttgcaa aaccatgtat acaatcaaac tcctcactat
    59821 ctttggaata tttttgttta atttggtttt cgttaaaatc gacaaacaat tttccactgg
    59881 ataataaatg aatcatgaaa cgatttacat ctgcctcttc aatttctaat tcctttgact
    59941 caagtttatt tttaatactt aaaaaatccg agacatctga aataaacaat tcgaacatat
    60001 tcttgatttt ttgaaaattc ttttgaatct caaaaatttg gtccgatact gacattattt
    60061 ccttggttgg ttcaatatca gagatgacaa tacgtttttc attgttgtta atttctaaat
    60121 aagctaatcg ctcgataata tcactatcat ttaattcagc atactcaaca tcaatttggc
    60181 gtaactgctt ctcagataga gagcttactt cctcttttac atcgctcatc ttattcctcc
    60241 cactcgctct tcagcaagcc atatatcaga ctgtcacagc ggtttccttg aacatccttt
    60301 cggtctctta tgcgagcttc gagggtaaag ccaagctttt ccgagactcg ttgactttga
    60361 aggttatatc caaagcaagt tagttcaatc ttgtgaagac caagttcttt aaaagctaga
    60421 tcaatcaagg cacacgctgc ttctggaaca taacctcgcc cccaatagtc tgggtgtaag
    60481 gtatagccga tttccagcac atcatcttca tggcgatggt tgaaatcgac agagccaacg
    60541 atcttatccg ttcctttgac gacaatcccg tagcctgctg ggagattttc cttttgatta
    60601 cgctccggaa gaatgtgctc cagataataa atctcatctt ccaaggtctt gactggagga
    60661 aaacctgctg gataggcaac ctctggcaaa ctagcatagt caaagatatc ctcagcatcc
    60721 gccacagtac ggactcgtaa aacgagacgt tctgtttcga ttttatctgg cagctcagtt
    60781 cttgccatcc ttcttcctcg cttttttgat gaaactgccc ttcatatcta cacgcttgtc
    60841 cagatagcga taaacgcgct gatatccatc tcccatgaaa taggttgggg caaacagttg
    60901 atttttaaaa tgtccctttt catccaggag ttctggaaca acaagtcgct caagaatctt
    60961 ggcaaagatg tggcaaatac cgtcttcctc aacaatccta tctacccgac aatctaaaac
    61021 aagtggacag gcgtctaaaa taggagtctg agttcattca gaaatttcat aatgcactcc
    61081 caaacgttcc aatttctcct gatgactgat aaaaccagcc tgctccatcg caagcataga
    61141 agtttcatca gaaatattca cagtaaattt ttgatactgt ttgatctgct ctgcggcatt
    61201 ctctcttgca acgactccaa tcacaaccca atctcctaga ctataagagg aactacaggt
    61261 cgtgatgtta tagccaaaat tctaatcttg atatcctaaa ataaaaacag gaaaaccata
    61321 atatagttta cttgtgttaa aagattgctt cataacaacc ccctttgact aagacgtaaa
    61381 agaaaagccc tgccatctac atgacaggga cgaatgtgtt tatccgcggt accacccaat
    61441 ttcgggcagt tgcccgcaac tctcgtcttt aaagcaaaaa gacactttta tttcaatttt
    61501 tcatccatta gcaaccagtt ttgacacatt tgtggacttc tcagcgccgc cactttctgt
    61561 aaaatgtggg attcaaaaca cctctaatgg ctctattgta gcaagatttt ttcggaaatg
    61621 caaggctcaa gaaaaattac ttgaacttga tgccattttc tttcaatttc ttgatggtag
    61681 ctgggccgat tcctttcaag gcaaggagtt ctttttcagt ccagtttttg aaatctgaag
    61741 cagacttgat tccttcatca tagaaagtct tggcacgatc aagtggaagt ccacccaaat
    61801 ttgctgcaaa atcttctaca gaattagcta ctttttgagc ttgctctttg gtagcttcta
    61861 ctgcttgttc aactttttta gaaacagcct taccagctgc gcttgctgac tgttctgcac
    61921 gcttcacgac tttttttgtc tcatctacaa ccttagtcac agtacttgaa aaggcacctg
    61981 cgcgacggag gccatttcgt aattgttttt tacgattgag tttctttgac atgataaaat
    62041 cctttcaata aaaaatccct gctctgacaa ggatttaaca taaacattct atcaagattt
    62101 tagtgaaaaa tcaagaatct ttctcgttta ataatttcgc tcaccaaaca agccttctgg
    62161 caaatcatgg aatcccttgc ctgctttgaa gttttcaaac ttaccaagca agaactgata
    62221 agcatccaag cgactctcgt agcgaatcat ggcatctttg gcacgctcgt cctggtcttc
    62281 ttcgtaaact ttttgacttt ccttgtgcgc catatcgtta atcatgattt gggtattgac
    62341 ccaagcttca aattccttca taaattcttg ttcgtaactc attttttctc cttattctaa
    62401 tccacgaaaa tagtccgtat caatctcacg gtagggctgg atatcctgaa catactccaa
    62461 cactccttgg aattctccgt cttcatcgtg tactgcagca taggtgatgt ggacaaactt
    62521 acctcgcgac tcagacttga accacatttc atacttgtct ttgcttccct cacgaagccc
    62581 cttcatgata gttttgacct tgtccaagta cttaggcgga tggcagagtt cgacattgcg
    62641 cccgacttgg gacggcgtcc gtttgaaaat catctcatca gctggcgtat tgtcattgta
    62701 atactggaaa atatcttctt tattgacaaa ggtaatctcc atagggagat gattgaggat
    62761 gagattggcc tgctcgactg aaagatagcc attaccaaaa gcctgttgac tatggcggtc
    62821 cagcacagct tccttttcct taggggtaaa ggtaatggta aaatggcctt ctggcgtatc
    62881 tatgacttgt tgaacttgac cttctgccgt atctagctgt acaggctcct ctgcaatctt
    62941 ttcctcaata aagctctgtc gttctggcac ccatttctct gacggacgga tgatggcata
    63001 gccataggca tcgctctcct ccgcaatctg aagccagtca tcctgagtaa aagactcaag
    63061 gagaatcatg aggaggatgg actcttcctt gaaaatcata ctttcaaact ctgtcgcaaa
    63121 agcttcaaaa gcttccttta cactgctaat tgacacttct ggtagtgact tggctgtcgt
    63181 tagagctgtt tgaaagagtt ccctaatctg atcatccact ccccacataa ctttgggagg
    63241 tgaatcgtgt ccatagcgct ccatgatagg aaagaagagt tcttccttac gttggtaatg
    63301 gatgtcaaat tgacccacaa gtcccatctg acgcaccaaa cccttacgca tctccgccag
    63361 catttcctcg tcttccatag actcataggt atctaacaat ctacgaatgc gaatcaaggc
    63421 cgcacggaga gccagatttt cttctttgaa gacacgaact gggtgacctg gatgctcagt
    63481 atctgaaact tcgacacctt tgatagcatt tttaaaaaga ttggcatgga catcacagag
    63541 ttccataaca tcttcaaaag tgacgcccga atccgagttc atcagctcgt gctccataag
    63601 ggaaatctcg atggctgaca cgcccgtaaa ggtcgcatca aagcgatctt gaaccgactc
    63661 aggagaggcg ccattgtgca attctaacaa aatatcccgt aggatatgaa tccgttcatc
    63721 tgtcattagt ctaatccaat cacttcgtag ccattcgctt ccagtgtgcg tacaatcttg
    63781 tccataggag ttcctgctag cttagaaccc tgtttaagtg atactttacg accaactgta
    63841 ttgcgcatta agggattggc aaggggttta aaacccaact ccactagaat ttccaagact
    63901 tctggatgct tgtccaccac ttctgcaaca ggaattgaca catcgatgat attgtccatg
    63961 acgacctcca ttgtatgttc taatactcaa tgaaaatcaa agagcaaact aggaagctag
    64021 ccgcaggttg ctcaaaacag tgttttgagg ttgtagatag aactgacgaa gtcagctcaa
    64081 aacaccgttt tgaggttgtg gatagaactg acgaagtcag taacatatat actgcaaggt
    64141 gaagctgacg tggtttgaag agattttcga agagtataaa atgattttac tgcttatatt
    64201 ataccatatg gaaagagaat aaaaaactag cagtggagtt cctgctagtt ctctgcaact
    64261 tggattacca tctagataag tttaaagaac caatccaata tcttgtaaaa cagcaattga
    64321 actgcaaaag aaatgatcat ccaaaagaat ttcacaatcc caataatcgg tttgataaaa
    64381 agaatagcaa gaagaccaaa aaaatttcat tctctctcct ctggcttaat gagccaccga
    64441 gccgtatcca ttagcttatc tgcaataaaa agtttgccca gaccaacaac gacatggtca
    64501 gctttcttta tcgttttcat cacttttaca ccttgcacgg tcaaaaagta attaccataa
    64561 attttagcaa aagctttgat aggattcata ttactctcct ttgatgattt cagcctcttt
    64621 tcggattgtt tcaacatctt cttgatattg aacttcacta tagttgacta gcttggataa
    64681 ttctttctgc aagctttccc ccattggttt catagttgca aaggttaaac cacctgaaat
    64741 gataccaccc aagataggaa taaatttccc tattcctttg gccagccctc ccttggtaag
    64801 attcacacca aatattttta agactttttt caaaataggg taccaaagcg tctttgttaa
    64861 agctttatta ggcactgttt tcattacctg tttggcaatt gttataccac cagcacgtag
    64921 caaagcagcg gttccattca cccctaacat tacgcctaga taaagcaaga gggtattttg
    64981 agcatcttca ctcaactcct cgcgtgaagc ccaaagatcc tcataaccat aaatataacc
    65041 taattcttga gccaatttca gagagaaagc ataaaattga gccacatcag ctggaatggt
    65101 aattgccata gcaagccctc caggtaatcc tgccaaaaca gaagtcccac tcgctaataa
    65161 tacattgtcc cgaatacaag cattagctac acgatctaat atttcttgag atagaagagt
    65221 cgttgggtct tgttccaata aggtaggaat atcttttgga tccaattctt tggaaaactt
    65281 atccactaaa aatttcgaac gatcaacctt aacaacaggt agtttcacca cttgttgcaa
    65341 tacttgcata gctaagtctt gttcagccat atacaaactc cttatttctt ttttgcacct
    65401 tatcatatta tatttcctac aaaaaaagca ttttctaatt agataacatt aaaaaataca
    65461 gaaccccttt t
//
LOCUS       DAVHLA010000007        64217 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVHLA010000007 DAVHLA010000000
VERSION     DAVHLA010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 64217)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64217)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64217
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.007"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(91..1227)
                     /gene="lctO"
                     /locus_tag="VVO77_000534"
     CDS             complement(91..1227)
                     /gene="lctO"
                     /locus_tag="VVO77_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEU5692592.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(1852..3342)
                     /gene="lysS"
                     /locus_tag="VVO77_000535"
     CDS             complement(1852..3342)
                     /gene="lysS"
                     /locus_tag="VVO77_000535"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEU5692593.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKTIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(3470..3616)
                     /locus_tag="VVO77_000536"
     CDS             complement(3470..3616)
                     /locus_tag="VVO77_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HEU5692594.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TSFQ"
     gene            3649..4566
                     /locus_tag="VVO77_000537"
     CDS             3649..4566
                     /locus_tag="VVO77_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275026.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEU5692595.1"
                     /translation="MYIAVWGSLGSFLLGLIVSIIRHYRIPVLAQVATAYIELSRNTP
                     LLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSAMQDSGIQVLFQGNNLLRILQGL
                     GVTIGISILSVLLSMMFGTVMGIIMTSHSRIIRFLTRLYLDFTRIMPQLVLLFIVYFG
                     LARNFNINISGETSAIIVFTLWGTAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYY
                     HIIIPQVLRRLLPQAINLVTRMIKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTASFW
                     IYGTILVLYFAVCYPISKLSTHLEKHWRN"
     gene            4567..5325
                     /locus_tag="VVO77_000538"
     CDS             4567..5325
                     /locus_tag="VVO77_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU5692596.1"
                     /translation="MSETILEIKELKKSFGDNPILQGLSLEIKKGEVVVILGASGCGK
                     STLLRCLNGLESIQGGDIFLDGQSIVENKKDFHLVRQKIGMVFQSYELFPHLDVLQNL
                     ILGPIKTQGRDKKEVTEEALQLLDRVGLLDKQHSFARQLSGGQKQRVAIVRTLLMHPE
                     IILFDEVTASLDSEMVREVLELINDLAQEGRTMILVTHEMQFAQAIADRIIFLDQGKI
                     AEEGTAHAFFTNPQTKRAQEFLNVFDFSQFGSYL"
     gene            5337..6209
                     /locus_tag="VVO77_000539"
     CDS             5337..6209
                     /locus_tag="VVO77_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU5692597.1"
                     /translation="MKLFKPLLTVLALAFALIFITACSSGGNAGSSSGKTTAKARTID
                     EIKKSGELRIAVFGDKKPFGYVDNDGSYQGYDIELGNQLAQDLGVKVKYISVDAANRA
                     EYLISNKVDITLANFTVTDERKKQVDFALPYMKVSLGVVSPKTGLITDVKQLEGKTLI
                     VTKGTTAETYFEKNHPEIKLQKYDQYSDSYQALLDGRGDAFSTDNTEVLAWALENKGF
                     EVGITSLGDPDTIAAAVQKGNQELLDFINKDIEKLARKTSSTRPMKKHFTQPTVTLLK
                     QMTWLLKVEKLISH"
     gene            complement(6289..6936)
                     /locus_tag="VVO77_000540"
     CDS             complement(6289..6936)
                     /locus_tag="VVO77_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5692598.1"
                     /translation="MNEIITLKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(6933..7631)
                     /locus_tag="VVO77_000541"
     CDS             complement(6933..7631)
                     /locus_tag="VVO77_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692599.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLANWDIGVLFIVDSLNACVLSLLCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            complement(7641..8393)
                     /locus_tag="VVO77_000542"
     CDS             complement(7641..8393)
                     /locus_tag="VVO77_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692600.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLNNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(8393..9157)
                     /locus_tag="VVO77_000543"
     CDS             complement(8393..9157)
                     /locus_tag="VVO77_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692601.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQFLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKLGAIFIPVAYMVVGGILWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(9253..9656)
                     /locus_tag="VVO77_000544"
                     /pseudo
     CDS             complement(9253..9656)
                     /locus_tag="VVO77_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(9836..10468)
                     /locus_tag="VVO77_000545"
     CDS             complement(9836..10468)
                     /locus_tag="VVO77_000545"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEU5692602.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            complement(10502..11203)
                     /gene="pyrF"
                     /locus_tag="VVO77_000546"
     CDS             complement(10502..11203)
                     /gene="pyrF"
                     /locus_tag="VVO77_000546"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEU5692603.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QLIKQATNPDFICLTPGIRPQGAAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            11524..11616
                     /locus_tag="VVO77_000547"
                     /pseudo
     CDS             11524..11616
                     /locus_tag="VVO77_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011516271.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(11938..12651)
                     /locus_tag="VVO77_000548"
     CDS             complement(11938..12651)
                     /locus_tag="VVO77_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5692604.1"
                     /translation="MLKRFLALVWLRCQIILSNKSILLQVLVPFAFTYFCKYLMETQG
                     KVNDQQELVLLMMCLPFSLALAVGSPITIILSEEKEKYNLQTLLLSGVKGSEYILSTM
                     FLPFLLTFVIMGTTPLILGVTIVHTFNYITIVLLTSLSIILFYLLIGLTAKSQVVAQV
                     ISLPAMILVAFLPMLSGLDKTVAKITDYSFMGLFTKFFTKWEGFSWNETLIPNLTLLI
                     WIVLLLTLITITIRKKKIS"
     gene            complement(12644..13483)
                     /locus_tag="VVO77_000549"
     CDS             complement(12644..13483)
                     /locus_tag="VVO77_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5692605.1"
                     /translation="MSMIEVSHLSKSFGDKIALNNISFTVKEGQIFGFLGPSGSGKTT
                     TINILTGQFLADKGQSIILGQKSQNLTSGELKRIGLVSDTSGFYEKMSLYNNLLFYSK
                     FYNISKSRVDNLLKRVGLYDSRKMVAGKLSTGMRQRMLLARALINKPAVLFLDEPTSG
                     LDPTTSRTIHELILELKTAGTTIFLTTHDMNEASLLCDYVALLNKGKLVEQGAPSELI
                     QRYNKDKKIKVTDYNGNQITFDFTSLEQVSQADLENIFSIHSCEPTLEDIFITLTGGK
                     LNA"
     gene            complement(13959..14834)
                     /locus_tag="VVO77_000550"
     CDS             complement(13959..14834)
                     /locus_tag="VVO77_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HEU5692606.1"
                     /translation="MDSRYSRTKGYYSLFYNEEYNKIQNKTVLVLGAGALGCYISLSL
                     SMYGVRKLIVADYDIIEPSNLNRQILYTESDVGKEKINVLSEKIHKYNSDVQVVPISI
                     KVSSLEELEKIVAEYGSIDFIVKAIDTPIDIIKIVNQFAVSHKISYISGGFNGCYLII
                     DNIYIPTIGSCFGCRNINKDINKYTLSDKTKWPTTPEMPAILGGIMTNLIIKIFLGCY
                     NETLIDNAYVYNMRNHALSQEKYVLENGECPICKKNNKVKDNNIRAKTFIRSVCFCLL
                     SGGVAFYLLLGSSLL"
     gene            complement(15029..15826)
                     /locus_tag="VVO77_000551"
     CDS             complement(15029..15826)
                     /locus_tag="VVO77_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M50 family protein"
                     /protein_id="HEU5692607.1"
                     /translation="MGLIDSMKSRKKINIFKISWDFNITLSEKLNYKRFNKNFEKILF
                     GIFPLALILQCFIMYIYRADILTNFQNFPITLNILLFWLLVVIISATIHEFSHAIIAN
                     NYQIEIPNCGIMLLLFNLAFFVDLSGVQFLKNKKQFLKIMLAGIASNSILSLTGLLVL
                     LFTSYKLLGLLFFIINLGMIFINSIPFFQYDSGIILRYLNSNNNNLNFQYIVQLLIAF
                     VIIYFPLSQLLQFLTPNIIVRSIGGVVVSILLSILYMIGRTKYVLRK"
     gene            complement(16617..17816)
                     /gene="divIB"
                     /locus_tag="VVO77_000552"
     CDS             complement(16617..17816)
                     /gene="divIB"
                     /locus_tag="VVO77_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEU5692608.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEESES
                     KEKEEQDKKLAKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     NQRSSRR"
     gene            complement(17826..18884)
                     /locus_tag="VVO77_000553"
     CDS             complement(17826..18884)
                     /locus_tag="VVO77_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEU5692609.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLAKVEHVGA
                     VTKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            complement(18888..20240)
                     /locus_tag="VVO77_000554"
     CDS             complement(18888..20240)
                     /locus_tag="VVO77_000554"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEU5692610.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIATD
                     KNTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGLFEEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLASKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRDVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(20344..20985)
                     /locus_tag="VVO77_000555"
     CDS             complement(20344..20985)
                     /locus_tag="VVO77_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5692611.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(20987..23008)
                     /locus_tag="VVO77_000556"
     CDS             complement(20987..23008)
                     /locus_tag="VVO77_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU5692612.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLNYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLTSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDTENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLTDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            complement(23079..23378)
                     /locus_tag="VVO77_000557"
                     /pseudo
     CDS             complement(23079..23378)
                     /locus_tag="VVO77_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
     gene            complement(23742..23996)
                     /locus_tag="VVO77_000558"
     CDS             complement(23742..23996)
                     /locus_tag="VVO77_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEU5692613.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            complement(24016..25857)
                     /gene="typA"
                     /locus_tag="VVO77_000559"
     CDS             complement(24016..25857)
                     /gene="typA"
                     /locus_tag="VVO77_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEU5692614.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            26019..26744
                     /locus_tag="VVO77_000560"
     CDS             26019..26744
                     /locus_tag="VVO77_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HEU5692615.1"
                     /translation="MRLDNLLAQEKVSRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            complement(26784..27011)
                     /locus_tag="VVO77_000561"
     CDS             complement(26784..27011)
                     /locus_tag="VVO77_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692616.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLEYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(27100..27480)
                     /locus_tag="VVO77_000562"
     CDS             complement(27100..27480)
                     /locus_tag="VVO77_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU5692617.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILRARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            complement(27480..27749)
                     /locus_tag="VVO77_000563"
     CDS             complement(27480..27749)
                     /locus_tag="VVO77_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEU5692618.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            27813..28721
                     /locus_tag="VVO77_000564"
     CDS             27813..28721
                     /locus_tag="VVO77_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEU5692619.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLSHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            complement(28775..29530)
                     /locus_tag="VVO77_000565"
     CDS             complement(28775..29530)
                     /locus_tag="VVO77_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEU5692620.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(29551..30480)
                     /locus_tag="VVO77_000566"
     CDS             complement(29551..30480)
                     /locus_tag="VVO77_000566"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEU5692621.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTVRPRKISKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTNASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            complement(30495..31118)
                     /locus_tag="VVO77_000567"
     CDS             complement(30495..31118)
                     /locus_tag="VVO77_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEU5692622.1"
                     /translation="MTDIKALALKYGGYTSLDKVYLVQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     DSDGLGRIFSENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            complement(31111..32349)
                     /gene="hflX"
                     /locus_tag="VVO77_000568"
     CDS             complement(31111..32349)
                     /gene="hflX"
                     /locus_tag="VVO77_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEU5692623.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKFQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDS
                     EVITGYISEKNKWRLEEFYD"
     gene            complement(32342..33226)
                     /gene="miaA"
                     /locus_tag="VVO77_000569"
     CDS             complement(32342..33226)
                     /gene="miaA"
                     /locus_tag="VVO77_000569"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEU5692624.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVLHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHFVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQETLYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTFEEASESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            33347..33517
                     /locus_tag="VVO77_000570"
     CDS             33347..33517
                     /locus_tag="VVO77_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEU5692625.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            complement(33565..34404)
                     /locus_tag="VVO77_000571"
     CDS             complement(33565..34404)
                     /locus_tag="VVO77_000571"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEU5692626.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRIDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(34501..35460)
                     /locus_tag="VVO77_000572"
     CDS             complement(34501..35460)
                     /locus_tag="VVO77_000572"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEU5692627.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTVGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            complement(35587..36585)
                     /locus_tag="VVO77_000573"
     CDS             complement(35587..36585)
                     /locus_tag="VVO77_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU5692628.1"
                     /translation="MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYS
                     DIHEGEPGYSAKLDRDHDGVACELKNAPKGAFKAKQSTAIQINTSSATTSGWVKQDGA
                     WYYFDGNGNLVKNAWQGSYYLKADGKMAQSEWIYDSSYQAWYYLTSDGSYAKNAWQGA
                     YYLKSNGKMAQGEWVYDSSYQAWYYLKSDGSYARNAWQGNYYLKSDGKMAKGEWVYDA
                     TYQAWYYLTSDGSYAYSTWQGNYYLKSDGKMAVNEWVDGGRYYVGADGVWKEGQASTV
                     SSSNDSNSEYSAALGKAKSYNSLFHMSKKRMYRQLTSDFDKFSNDAAQYAIDHLDD"
     gene            complement(36635..37252)
                     /locus_tag="VVO77_000574"
     CDS             complement(36635..37252)
                     /locus_tag="VVO77_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU5692629.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALTLELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCSYPTLLICGSKDKPNL
                     SSMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            complement(37253..38974)
                     /gene="pabB"
                     /locus_tag="VVO77_000575"
     CDS             complement(37253..38974)
                     /gene="pabB"
                     /locus_tag="VVO77_000575"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEU5692630.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKNLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANQDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQHLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            complement(39035..44746)
                     /locus_tag="VVO77_000576"
     CDS             complement(39035..44746)
                     /locus_tag="VVO77_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU5692631.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGTMGLVVLPSAGAVDPVATLALASREGVVEMEGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPAEES
                     KVEQAGEPVAPRKDEQAPVEPENQPEAPEEEKAVEETPKQEESTPDTKAEETVEPKEE
                     TVNQSIEQPKVETPAVEKQTEPTEEPKVEQAGEPVAPREDEQAPTAPVEPEKQPEVPE
                     EEKAVEETPKPEDKIKGIGTKEPVDKSELNNQIDKASSVSPTDYSTASYNALGPVLET
                     AKGVYASEPVKQPEVNSETNKLKTAIDALNVDKTELNNTIADAKTKVKEHYSDRSWQN
                     LQTEVTKAEKVAANTDAKQSEVNEAVEKLTATIEKLVELSEKPILTLTSTDKKILERE
                     AVAKYTLENQNKTKIKSITAELKKGEEVINTVVLTDDKVTTETISAAFKNLEYYKEYT
                     LSTTMIYDRGNGEETETLENQNIQLDLKKVELKNIKRTDLIKYENGKETNESLITTIP
                     DDKSNYYLKITSNNQKTTLLAVKNIEETTVNGTHVYKVTAIADNLVSRTADNKFEEEY
                     VHYIEKPKVHEDNVYYNFKELVEAIQNDPSKEYRLGQSMSARNVVPNGKSYITKEFTG
                     KLLSSEGKQFAITELEHPLFDKIKAGTVKNINFENIDINVSNQDNIATIANEINGTTR
                     IENIKATGTITARNNVAGFVNNIKENAALENVAFIGNINSVGNNSTVGGIAGSNYMGF
                     VNKAYVDANITAANASASMLVPLVTYMLNSYQYGTKSKVTNSVAKGTLDVKNTRFVGG
                     VVAKTWPWGVIKDIVTYAKVIKGEEVYGSNEINDGDARQFLSDIYRVNGASSGANNFT
                     NLQKIKQLTKEQADAKVATFNITADKLESELSPLAKLNEEKAYSSIQDYNAEYNQAYK
                     NLEKLIPFYNKDYIVYQGNKLNKEHPLNTKEVLSVTAMNNNEFITNLDEANKIIVHYA
                     DGTKDYFNLSSSSEGLSNVKEYTITDLGIKYTPNIVQKDNTTLVNDIKSILEPVDLQS
                     QTMYQHLNRLGDYRVNAIKDLYLEESFTAVKKNLTNLITKLVQNEEHQLNDSPAARQM
                     LRDKVEKNKAALLLGLTYLNRYYGVKFGDVNIKELMLFKPDFYGEKVSVLDRLIEIGS
                     KENNIKGSRTFDAFGEVLAKYTKSGNLDVFLNYNRQLFTNIDNMNDWFIDATKDHVYI
                     AERASEVEEIKNAKYRAYANLNVAQHRKMILPLLNITKSHMFIASNYNAIAIGSAEKL
                     GKKSLEDIKASVDYAADGYRNYYDFWYRLVPDNVKQYLLRDTVIPIWEGYNAPGGWVE
                     KYGRYNTDNVYTPLREFFGPIEKYYGYNGTGAYAALYDNPMDPRSDVSYVALNMIGDY
                     GISVYTHETTHINDRKIYLGGFGRREGTDAEAFAQGMLQLPVPGSGFNEYGSLGLNTV
                     FKKPNDGNQWYDTDPKSLTTRDDIDKYMRGYNDALMLVDHLEADAVINQNNKELNGAW
                     FKKIDKKFRDASQLNQWDEIRNLTTEEKDNLNITSIDSLIDQQLMTNRQIGNRVYKPE
                     VVSQYDQSPYVGVEMTAGIYGGNTSKGAPGAVSFKHNAFRLWGYYGYLNGFLGYTSNK
                     YKQQSTKDGESVLSDEYIIKKISNNTFNTIEEFKKAYFKEVKDKATKGLTTFEVNGSS
                     VSSYDDLLTLFKEAVKKDAETLKQEANGHKTVSMTNTVKLKEAVYKKLLQQTDSFKTS
                     IFR"
     gene            complement(44768..45331)
                     /locus_tag="VVO77_000577"
     CDS             complement(44768..45331)
                     /locus_tag="VVO77_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001006373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEU5692632.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALTSRPKLIGGARAHYPQDAIRKF"
     gene            complement(45447..47138)
                     /locus_tag="VVO77_000578"
     CDS             complement(45447..47138)
                     /locus_tag="VVO77_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU5692633.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            complement(47135..47872)
                     /locus_tag="VVO77_000579"
     CDS             complement(47135..47872)
                     /locus_tag="VVO77_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU5692634.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            complement(48140..49252)
                     /gene="msrB"
                     /locus_tag="VVO77_000580"
     CDS             complement(48140..49252)
                     /gene="msrB"
                     /locus_tag="VVO77_000580"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEU5692635.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            complement(49263..49829)
                     /locus_tag="VVO77_000581"
     CDS             complement(49263..49829)
                     /locus_tag="VVO77_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEU5692636.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            complement(49849..50559)
                     /gene="ccdA2"
                     /locus_tag="VVO77_000582"
     CDS             complement(49849..50559)
                     /gene="ccdA2"
                     /locus_tag="VVO77_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEU5692637.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGFLVLFGNASILSQLFE"
     gene            complement(50770..51630)
                     /locus_tag="VVO77_000583"
     CDS             complement(50770..51630)
                     /locus_tag="VVO77_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEU5692638.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSINFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQFLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGVLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDQVFKKD"
     gene            complement(51809..53863)
                     /locus_tag="VVO77_000584"
     CDS             complement(51809..53863)
                     /locus_tag="VVO77_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEU5692639.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            complement(53875..54129)
                     /locus_tag="VVO77_000585"
     CDS             complement(53875..54129)
                     /locus_tag="VVO77_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692640.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERSVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            complement(54122..54679)
                     /locus_tag="VVO77_000586"
     CDS             complement(54122..54679)
                     /locus_tag="VVO77_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU5692641.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            complement(54663..55619)
                     /locus_tag="VVO77_000587"
                     /pseudo
     CDS             complement(54663..55619)
                     /locus_tag="VVO77_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            55711..56070
                     /locus_tag="VVO77_000588"
     CDS             55711..56070
                     /locus_tag="VVO77_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEU5692642.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSILAIILVFFFLLKKLSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            56282..57136
                     /locus_tag="VVO77_000589"
                     /pseudo
     CDS             56282..57136
                     /locus_tag="VVO77_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(57384..64070)
                     /locus_tag="VVO77_000590"
     CDS             complement(57384..64070)
                     /locus_tag="VVO77_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEU5692643.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SSQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVEEYEVDKWEIAEEDKAKLAIPGSRIQATGYLEGQPIHATLVVEEGNPAAPAVPTV
                     TVGGEAVTGLTSQKPMQYRTLAYGAKLPEVTASAKNAAVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLNAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQEPSLPATVTVEYDKGFPKTHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAIRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTANVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLTVEWEEVPAEN
                     LTKAGQFTVRGRVLGSNLVAEVTVRVTDKLGETLSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPSKLVLERYVGPGFEVPTYYSNYQAYESGHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IQLTKEKPVSAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKVGKERIFT
                     VINPDGSKEEKLREVVEVPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSEADQTN
                     KAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
BASE COUNT        19073 a        13810 c        11461 g        19873 t
ORIGIN      
        1 ttatttcatt ttactatagt tttcgatagc aatttattct tccaatacac gaagaaaaac
       61 ctccacattc agtggaggca atctgtttta tcaatacaat tttaagtcac gagggtcaac
      121 tgggaaggtt gggttgtatg gattgtgacg gagcttaaag tgtttgacat cttcaatggt
      181 ctgagctcca gacaattgca taactgtctt caattccgca ttcaagtgtt caaagacttg
      241 acgcacaccg acactaccac cgagagccaa gccataaata acagggcgac caatagctac
      301 caagtctgct cctgaagcca aggctttaaa gacgtgttga ccacgacgaa caccagagtc
      361 aaagacaatc ggcacacgtc tatcaactgc ttctgccact tcttgaagcg agtcaaaggc
      421 agctggtcca ccgtcgattt gacgaccacc gtggttggtt acccagatac cagaagctcc
      481 tgcagcaagt gaacgttcaa cgtcctcacg gcattgtggt cccttgacat acacaggaag
      541 accagagtat tcagcgataa attctacatc gcgtggagac aagcgttgtt tagctgattt
      601 gtaaacaaag tccattgatt taccagcacc ttctggcagg tattcttcaa caatcggcat
      661 gccaactggg aagacaaaac cattacgctt atccacttca cgattccccc ctacagtagc
      721 atctgccgtc aagacaatcg ctttataacc ttcagccttc acacggtcca tgatgtggcg
      781 gttgataccg tcatccttac taaagtaaaa ttggaaccaa tggggtgtcc cttgaagggc
      841 ttcagaaatc tctggaaggt caacagtaga gtaagagctg gttgtataaa gagaaccaaa
      901 ctcatgcaca ccacgcgcag tcgccacttc cccctgttca tttgccaatt tatgagccgc
      961 aacaggcgcc ataatgattg gtgaagatag tttttcacct gcaaattcaa tctctgtact
     1021 tggattttca acatcgcaaa gtgtatgagg aacgatgagt ttgtggttaa aggcgcggat
     1081 attctctctt aaagtgaaag tatcttccgc cccactagcg atatagccaa atgctgcttt
     1141 aggaataact tgttgcgcca ttggctccaa atcataggta ttgatgaagt ctacatgacc
     1201 ttctgcattg cttgttttgt atgacataaa atgccctcct tgattaagta agcgtttgct
     1261 ttttactaca caactataat aactcttttt tcaatcattt tcaagagttt tgcttaaaaa
     1321 ccatcttatt ttttcataca atatactagc cctactttcc ttaaactcta aactttagtc
     1381 tatattaagt gaatcgttga gattttttgc tgccaggcat ttgaactact tttttatttg
     1441 cggattctat ctactaatac tataaaaaaa caagtgaata agacaccaga acatcctcta
     1501 ataggaccta tggacttata tcagtcccat atatactgtt taagcaagat actatcctag
     1561 ttgacgctaa cttcctatcc cacttattaa ttttttattt atagtgaatc tgaacaaatc
     1621 aattggggaa tccaagtcaa tttctagtac tttttgaaca gtttcagcgt actatcgtaa
     1681 aatgaaataa aacatgcaca aattgcttag ggaatttaaa ccaatttcta acaatgtctt
     1741 agaaatcaaa gtgtactatt tcaacttcaa tatactacac ttcattttct ccttaaattc
     1801 agtctctttt tgaatcaaaa aatcccctgg taagagccag aggataagaa tttatttcat
     1861 tgttgggaag agcaatacat cacggatagt tgttgtatca gtgaggagca tgcagagacg
     1921 gtcgataccg attcccaaac cacctgttgg tggcataccg tattcaagag cttcaatgta
     1981 gtcatagtcg attcctgtcg cttcatcatc accaagttct ttggctttag cttgggcttc
     2041 aaaacggcta agttggtcga ttgggtcgtt caactcagta aaggcattac cgtactcctt
     2101 agtcatgata aagagctcga aacggtcagt aaagcgttgg tcttcaggat ttttcttagc
     2161 gagtggagat acagctactg gatgtccata gacaaaggtt ggttggatta aagtttcttc
     2221 aacaaactct tcaaagaagg cattgatgat gtgaccaacc tcagtgtagt gtttctcaac
     2281 tggaactttc ttctcagcag cgatagtttt agcttcttcc aaagtcatgt cttgccagaa
     2341 atcgacacca gtaatttctc tgatagcatc caccatatga acacgcttaa atggttcgtt
     2401 aatcttgatt tcagtacctt ggtagttgac tgggccatcg cctttgactg atttagcagc
     2461 atgttggata atgccttccg tcaagtccat gatatcttgg aagtctgcat aagcttggta
     2521 aacttcgata gaagtgaact cagggttatg agtagcgtcc attccttcgt tacggaagat
     2581 acggccaatt tcatagacac gttccatacc acccacaata aggcgtttta agtgaagctc
     2641 agtcgcgata cgaagcacca tgtcaatgtt ttgggcattg tggtgggtga taaatggacg
     2701 ggcagcagca ccaccggctt cattatgaag aacaggtgtt tccacttcaa ggaatccttt
     2761 ttggtcaagg taacgacgga tttcagagat gatttttgaa cgagtgacaa agcgttcaaa
     2821 gctttcacga ttagaaatca agtcaaggta acgtttacgg taaattgttt caacgtctgt
     2881 caaaccatgg aatttctcag gaagaggacg aagagcctta gacaagtgtg tgatgtgggt
     2941 tgccttgata gagagttctc ccatatccgt acgcatcact tcaccttcga caccaaggaa
     3001 gtcaccaagg tctgcttttt tgaagatttc gtagttttct tcaccgacag catccttacg
     3061 aacatagatc tgaatctggc cttcgcggtc ttgaaggtgg gcaaaaccaa cttttccttt
     3121 accacgtttg gttaccaagc gtcctgcgat agtagctgtt tcgtttttat cgtgtaattg
     3181 ttctttatcg aggttggcat atttatcttt taattcttgt gaatttgcag tacgttcaaa
     3241 acgttttccg aaaggatcga ttccttgttc gcggagcgca gccatttttt cacggcgaac
     3301 gatctgctgg tcatttagtt cttccatatg ttctgtagac atgggatcct cctagtttta
     3361 ctcaaaattg aatacgatga gtcatttttt gcgatactcc cattttatca taaataagca
     3421 agaaattcac ggataatctt taaaaactaa aaagaacctg acgctaaaat cactggaaag
     3481 aagtgaaagt atcttccgcc ccactagcga tatagccaaa tgctgcttta ggaataactt
     3541 gttgcgccat tggctccaaa tcataggtat tgatgaaatc tacatgacct tctgcattgc
     3601 ttgttttgta tgacataaaa tgcactcctt gataagtaag cgtttacttt gtatattgca
     3661 gtttggggaa gtttgggatc ctttctgctc ggtttaatcg ttagtatcat ccgacattat
     3721 cgaatccctg ttttggcgca agtagcgaca gcctacattg aattgtcacg taatacgccc
     3781 cttttgattc aactcttctt tctctacttc ggtcttcccc gaatcgggat tgtcctatct
     3841 tcagaagtct gtgcaacgct tgggcttgtc tttttaggag gctccgccat gcaggattcg
     3901 ggaatccaag tactctttca aggaaataat ctcctgagaa tcttacaggg attgggcgtt
     3961 acgattggga tatccatcct gtctgtcctc ttatccatga tgttcggaac agtcatggga
     4021 atcatcatga cctcccattc tagaatcata cgatttttaa cacgattgta tctggacttt
     4081 acccgtatca tgccccagct ggtgctactc ttcatcgttt actttggctt ggctcgaaac
     4141 tttaatatca atatctcagg tgagacttca gctattatcg tttttaccct ctggggaaca
     4201 gctgaaatgg gagacttggt acgtggagct atcacttctc tccctaaaca tcagtttgaa
     4261 agtggacaag cactcggctt gactaatgtt caactttact accacatcat catcccacaa
     4321 gtcttgagaa gactgctacc gcaggctatc aatcttgtca ctcggatgat taaaaccact
     4381 tcattagttg ttttgattgg ggttgtggaa gtgaccaaag ttggacaaca aatcatcgat
     4441 agcaatcgcc tgaccatccc aactgcttca ttttggattt atggaaccat tctagtctta
     4501 tatttcgcag tttgctaccc tatttccaaa ctatccactc acttagaaaa acattggaga
     4561 aactaaatgt ctgaaactat cttagaaatc aaggaactaa aaaaatcctt cggagacaat
     4621 cccatcctcc aaggactttc tctagaaatt aaaaaagggg aagttgttgt catcctaggg
     4681 gcatctggtt gtgggaaaag taccctcctt cgttgcctca acggcttaga aagtattcaa
     4741 ggtggagata tttttctgga tggtcagtct atcgttgaaa ataaaaaaga ttttcaccta
     4801 gttcgccaaa agattggcat ggtctttcaa agttatgaac tctttcccca tctggatgtc
     4861 ttacaaaacc tcatcctagg ccctatcaaa actcaaggaa gggacaagaa agaagtaacg
     4921 gaagaagctt tgcaattact agatcgtgtc ggtttgctgg ataaacaaca tagctttgcc
     4981 cgtcaattat ctggtggaca gaagcaacgt gttgcaattg tccgtaccct cctaatgcat
     5041 ccagaaatca tcctttttga cgaggtgact gcttcgctgg attcagaaat ggtgcgtgag
     5101 gtgctggaac ttatcaatga tttggcccaa gaaggccgta ccatgatttt agtaacccac
     5161 gaaatgcagt ttgcccaagc cattgctgac cggattatct tcctcgacca agggaaaatc
     5221 gctgaagaag gaacagctca tgccttcttt accaatccgc aaaccaaacg agcccaggaa
     5281 tttttaaacg tctttgactt tagccaattt ggctcatatc tataaaggag attcttatga
     5341 aactattcaa accactctta actgttttag cacttgcctt tgcccttatc tttatcactg
     5401 cttgtagctc aggtggaaac gctggttcat cctctggaaa aacaactgcc aaagctcgca
     5461 ctatcgatga aatcaaaaaa agcggtgaac tgcgaatcgc cgtgtttgga gataaaaaac
     5521 cgtttggcta cgttgacaat gatggttctt accaaggcta cgatattgaa ctagggaacc
     5581 aactagctca agaccttggt gtcaaggtta aatacatttc agtcgatgct gccaaccgtg
     5641 cggaatactt gatttcaaac aaggtagata ttactcttgc taactttaca gtaactgacg
     5701 aacgtaagaa acaagttgat tttgcccttc catatatgaa agtttctctg ggtgtcgtat
     5761 cacctaagac tggtctcatt acagacgtca aacaacttga aggtaaaacc ttaattgtca
     5821 caaaaggaac gactgctgag acttattttg aaaagaatca tccagaaatc aaactccaaa
     5881 aatacgacca atacagtgac tcttaccaag ctcttcttga cggacgtgga gatgcctttt
     5941 caactgacaa tacggaagtt ctagcttggg cgcttgaaaa taaaggattt gaagtaggaa
     6001 ttacttccct cggtgatccc gataccattg cggcagcagt tcaaaaaggc aaccaagaat
     6061 tgctagactt catcaataaa gatattgaaa aattagcaag gaaaacttct tccacaaggc
     6121 ctatgaaaaa acacttcacc caacccacgg tgacactgct aaagcagatg acctggttgt
     6181 tgaaggtgga aaagttgatt agtcattaac tcttaaaagg aactggattt taagctccaa
     6241 tcccttttta agattttacc tataacatcc tgagtctatc taagatgttc aatctgaaca
     6301 cagtgtacat actttatctt ctattgcata tactttatca cataagatac gaatatcctc
     6361 ttcactatga ctagcaatca aaattgttgt ccctttttca ctagagagct ttctaaacaa
     6421 tgttctcata ttttctacac ttgatttatc caaggcattc ataggttcat ctagtaaaag
     6481 aatagaggga ttctccataa ttgcttgagc aatccctagc tttttcctca tacctagcga
     6541 ataagtttta actttctggt ctttttgctc atatagacca actattttca gtgtatcatt
     6601 gatttcctga ttaccaacta ctcctcgtat gcttgccaaa tattgtaaat tcttaaagcc
     6661 actataataa tttataaaac caggttcttc aatcaaagct cccaaattag ctggaatttt
     6721 tctctcagga acaatatttt ccccattgat taacacttct ccataagacg gactatataa
     6781 accagctatt aatttaaaca atacactttt acctgagcca ttcgcaccag taattcctat
     6841 aatttccccc tgtttacaac taaaattaag gttttgaaaa acacatgttt tttttaattt
     6901 caactcaata ttttttaatg taattatttc attcattcta taaacctcct cttttgacga
     6961 gtgaaataga aaatgctttt aaaaagaaag actaaaaata gcaactgaag aaataaatct
     7021 cgtcctatat ctccattccc tcgattcaaa atataaaata gataattagt tcgatttcct
     7081 acaaatagac caccaaacac aatcatgagt aaaaagaaac taacgcaagc aaagttcatt
     7141 tgtacattcg ctcctagtgc gtataacata aagcaaagca aggatagcac acaagcattc
     7201 aaagaatcaa ctataaacaa aactcctata tcccagtttg ctaactgtaa cataaattga
     7261 atcactagaa cttttaccat gattaaaatg agtccataaa gaaaacaggt ccaaatctga
     7321 tacctaatcc agagcttaat agaagaaaat cgaatcactt ccataaagaa atcggatgct
     7381 cttctacgat atacaactgc tagaaaaaat gtatgaataa taaaccaatg aagcaaccat
     7441 atagataaga ctaaaaaaga gttttgactc agattaggcc cttttaaaat ttctataaca
     7501 agtctatcat ttccttctaa ccaataccat aatcctaaac aaatcaatat ccaaaaaaga
     7561 acataacccc aaaagtactt ggtatagatt atctgattca acctccacat gtgactactt
     7621 aactttccca tttccaactt ttacactctc ctccagtttc tatgaacaga aaatacagtc
     7681 aatggaatta tgatagatag taatgtaagc caataaatca atgcatacgg attggaattt
     7741 accatatact gaaaaattgg caataatcca attatcccat tgttcaactg ataaatccag
     7801 aataaggatt ctacaaataa aaaagtaaac agaaatacta agctcatgtt tgatttttta
     7861 aaccaagaaa aactgctaat agtaagtaag gataaaaaga aatagtatgc tatataagag
     7921 aaaaaaaatc ctataaagaa actagcattg tttgcaatac ttataccata aaattctctt
     7981 aaaaaatcaa cctcctttat ctccaaagag aagctaaaac cattactaaa tgcaattaga
     8041 aaaatcaata aaaataaagt cgccgtccaa atccccgtac taagagctgc taatttgaaa
     8101 ctaaaactgg taaagtgctt aattgatttc agacgaatgc gacactccaa cctattaaaa
     8161 tagttattca tcaaataaaa aaagaacaat atatatgtga acggaaagca atatactcca
     8221 gtcgtcatat cttgaagtaa aactaaaatc cattctaata catttggatg gattgaatat
     8281 tggcgacagc gcaataaata tactgtacta gataaaacac aggatagcag taatataaaa
     8341 taaaccaata ctgctaagaa atctttttta taaaattgaa caaattgttt cattatacat
     8401 agtcctctga atgtagaaaa aatgtaccat aaacaaccaa acaactaaca aataaaataa
     8461 aagcaagatg cccactaact aaggaaagac tgatatcttt ctgatatccc aaagctagcg
     8521 ttgtcacagg ttctaagtaa gatagcccta aaatagccca taaaatacca ccaaccacca
     8581 tataggcaac tgggatgaaa atagctccta attttttctt cactagcaaa gcactagcta
     8641 gtccaaaaat agagaacaca gcgccccaaa ctccatacca gagagtcgtc acaagactat
     8701 agagaaactg attagaatca aataattctt ttaaggcacc actataatct ccaatataaa
     8761 tttcctgata aggagtcact aaaagattaa ttcctaataa taataaatag gggagaaaaa
     8821 agactagaaa agaagaaata attgcagtac tacctacaat agctagatac ctctttttag
     8881 aaattcggca caattgtgct gttagaaaat gactctcagc atcctctatt atctgactag
     8941 aatagggcag tgtacagata agtgcagcta ctaggctaat cggtgaaaat cctcgaatag
     9001 aagaagcggc aaaaaaaatc gataaacctt caattttata aataccattg aaagcaagga
     9061 aatttcctaa actcatgcaa agaagggtca aaaataaaga catataaaac cgaggtgatt
     9121 gaacgactcg tacaagatta caaatgaaaa attccatcct tactcctcct tataataaaa
     9181 atagggtgta gcattctttt ttcatgctac acccacaatc aaccatcttt aaggcttact
     9241 ctgacaagta agttaataag aatctggact ccaagaacct gaagtatgaa ttcttacatg
     9301 atttccaaat tgtggcgcca tagctaatct agtaccagaa ccaatataat tgtcaccacc
     9361 tccattatag tacatgacaa tcctagagcc agaccccaat gaatataccg gggtaatatc
     9421 tgacccacta taggcgctac gaatagaggt atttaacctt ttaccgccac cagtgctgtc
     9481 actattatta attccagcag aggcgttttc tttctcaagc tcactagttg tatccgaacc
     9541 ccaacgcggc aacgttaaat cataatttcc aatctgtcta gctaaaactg tagggagaaa
     9601 caaactagat gcaattgtaa ctacgcaaaa aaggaatata tttttcttct tttcatgaca
     9661 tcgtcctctt aagaagtgat aaacaagata gttgattgat caatttgata catattacat
     9721 tttcattata tcaataaaag aaagcgttgt caattatttt atttaaaata ttatcatatt
     9781 ttaaataaaa tggtaaaaga gactcggtag cctcgtctct ctttatctta ctgacctaac
     9841 cttcttgcca attttcttgg tcttctttaa agcgttttag aagatcaagg ccctctggcg
     9901 tgatgtaacc ttcttcttgg gctagatgga taagctcgct atagtttgaa agcgtcacaa
     9961 gtttaacacc agcatctgca aagttcttat ctgcttttgg caattggtag ctgaaaatcg
    10021 ctacaactcc aagtacatct gctccttctc gcttggctgc tgctacagct tcaagaactg
    10081 aaccacccgt tgaaataagg tcttcaacca ctaccatttt ttgaccttga gctacgcgac
    10141 cttcgatttg attaccagct ccgtggtctt ttggtttgct acggatgtag gcaaaaggca
    10201 agtccatctt atcagcaata atggctccgt gtggaatccc tgctgttgca gttcctgcaa
    10261 tcacttctac ttcaggaaag gcttctttga tagcttccac aaaaccattt tcaattaggg
    10321 tacgagtttc tggataggct agtgtcacac gattatcagt gtaaatcggt gacttgatac
    10381 cagacgccca agtgaagggt tcctctggtt tgaggtaaac ggcttggatt ttcaagaggt
    10441 ggctagcgat atctttagca agtgtcatgg tattctcctt ttatttttct aatctagttc
    10501 tttaattcca gtcctgtgtc cattcatcct tgatggcatg ataagctgca acaggatcct
    10561 cagcttgggt aatgggacgt cccactacga tatagtcact accaatttga taagcatctg
    10621 ctggcgtcat gacgcgtttt tggtctccaa cagcagctcc ctgtgggcga atccctggtg
    10681 tcagacagat aaaatctgga ttggtggcct gcttgataag ttgaacttcc tgtgccgagc
    10741 aaacgacacc atccaagcct gcttcagctg tcttcttggc atagtggatc acagactctt
    10801 gtaggcttgt ttggatattt tgaaactcct gcatctgggc ttctgatgtt gatgtcagct
    10861 gcgttacagc gatcaatttt gcttgacttc caagaccttc acgcgcagcc ttcatcatct
    10921 ctacaccacc agccgcatga acattggtca tatcgacacc aagctgagac aagaccttca
    10981 tggctgactt gactgtatta ggaatgtcat gaagtttgag atccaaaaag acactatgac
    11041 ccaaaccttt taagtaggac acaatctcag gccccgctgc gtaataaagc tccatcccta
    11101 ccttgagata aaggctttct tctgctggga aaagagctaa aaattccttg accgcctcaa
    11161 aactaggaaa atcaagagca atgattggac gatgttctcg cataggtttc tccttttacc
    11221 tttactagtg agagagtctg gccaacagaa gccacgaaaa aaggaacctg ccaacagcaa
    11281 ggttccacga aaaatgggta gtctccaccc tttcaccgtc taaccttagc tgcctctctg
    11341 gactgcttta aaggttttct attattctat tatttctact agcacttgtc aagtaaaaac
    11401 atggtcacgt atgtgttgac tgctattgaa cacctcacaa gactctttcc aaaagaatag
    11461 ttaaagactt tcactgagga cagagaaaaa gagtttgctt gttacccttt aattgaacaa
    11521 atgggaattc tgttttattt tgcggatgcc tattcatctt ggcaaagggg aagtaatgag
    11581 aatgcgaatg gacttcttcg tgagtatttt cttaaaccga tttggcaaca attaccgaaa
    11641 aaatccttaa tggtgctttg ctagcttatt aatcaccgtt cccaaaaata cttggattac
    11701 aagacaggtt ttgaagcact tatagaggag atttaaaaat gttgcatttt ttattgcaat
    11761 ttatcagtta tcttatcacc caaaacttct gcaattagta tgagcactat tgttattttt
    11821 cttttttcgt acactcaaat caaaatatag caataagact attctgtaga attgctgtca
    11881 aaaagatcag ttcatttttc cttcccactt gtgtttataa tcattaaaat aactcaatta
    11941 agaaattttc tttttcctaa tagttatcgt aattaaagtt aatagaagaa caatccaaat
    12001 aagtagtgtt agattaggaa ttagagtttc attccatgaa aatccctccc attttgtgaa
    12061 aaacttagta aacagtccca taaaactata atctgttatc ttcgcaactg tcttatccaa
    12121 accagatagc atcggtaaga aagcaactaa aatcatagca ggaagactga taacctgagc
    12181 tactacttgg ctcttcgcgg ttaaacctat caataaatag aataaaatga tggataaaga
    12241 ggttagaaga acgattgtaa tataattaaa agtatgtaca attgtaactc ctaaaataag
    12301 aggagtagtt cccataatca caaaagttag caaaaaagga agaaacatcg ttgataaaat
    12361 gtattcggat cctttaacac cactcaacag aagagtttgt aaattgtact tttctttttc
    12421 ttcagacaag ataatagtta taggacttcc aacagccaaa gccaaagaaa aaggtaaaca
    12481 catcatcaaa agaactaatt cctgttgatc gttgaccttc ccctgtgttt ccataagata
    12541 tttacaaaaa tatgtgaaag caaaaggcac taaaacttgc aataaaatac tcttattgga
    12601 aaggataatt tgacaacgca accataccaa agccagaaac cgtttaagca tttagctttc
    12661 ctcctgttaa tgtgataaaa atatcttcta aagtaggctc acatgaatga attgaaaaaa
    12721 tattttccag atcagcctga gatacctgtt ctagtgatgt aaaatcaaaa gttatctgat
    12781 tcccattata atctgtaacc ttaatctttt tatctttatt atatctttga atgagttcag
    12841 aaggagctcc ttgctcaact aatttccctt tatttaataa ggcaacataa tcacataaaa
    12901 gacttgcttc attcatatca tgagtcgtta gaaaaatcgt tgtccctgct gttttcaatt
    12961 ctaaaattaa ctcatgaatt gttcgagaag ttgtgggatc tagacctgag gtcggttcat
    13021 ccagaaagag tacagcgggt ttgttgataa gagctcgtgc taaaagcatt cgttgcctca
    13081 ttccagtgga taattttcct gctaccatct tgcgactatc atataatcct actcgcttta
    13141 acaaattatc aacacgtgat ttactaatat tataaaattt actataaaaa agaagattgt
    13201 tatacagaga cattttctca taaaatccac ttgtatcgct aaccaatcca attctcttta
    13261 attcaccgct tgttaaattt tgagattttt gtcccaaaat aatagattgt cctttatcgg
    13321 caaggaactg cccagtcaga atattaatcg ttgtggtttt tccagaacca gatggtccta
    13381 aaaatccaaa aatctgacct tctttaacag tgaagcttat attatttaaa gctattttat
    13441 caccaaaact ttttgataaa tggctaactt caatcatact cattgcacct cctttatatt
    13501 ctacattttt acttaacatc tatttactta gctttatcaa ataaacgtct taaaaaaaac
    13561 aataacatta agcatataac cgttagcaag attgtttcaa tattattgat aatatgatac
    13621 attctcaagc agtataaaat aattatatat atgcaaatgc tcattatacc tattttttta
    13681 aacatactaa gcctccttgc caaataataa agttatataa taactaagac acactatacc
    13741 taacataata aatatccaca gcattaaaaa tattatcata caaataaaaa tatccactgg
    13801 taactgaata aatgttctaa aattaacaag caaaaataaa atctcaaacg atgaaaaaag
    13861 ccatactata ttttccaatg atgtttgaat atttttattg tagtaagcat aatatatagc
    13921 aaaaataata cccaagaaca atactattaa ttgtgtttct ataacagtga actgcccaat
    13981 agcagataaa aagctactcc tcctgataat aagcaaaaac aaactgaacg aataaatgtt
    14041 ttcgctctaa tattgttatc tttcacttta ttattttttt tacaaattgg acattctccg
    14101 ttttccagaa catatttttc ttgacttaga gcatgatttc tcatattata aacgtaagcg
    14161 ttatctatta gggtttcatt ataacatccc agaaatattt taattattaa attagtcatt
    14221 atccctccca aaatagcagg catctctggt gtagtcggcc actttgtctt atcagataaa
    14281 gtgtacttat ttatatcttt gtttatattc cgacaaccaa agcaagaacc gatggtaggg
    14341 atatatatat tatcaataat aagatagcat ccattaaacc ctcctgatat gtaggatatc
    14401 ttatgcgata cagcaaattg attgacaatt tttataatat caatgggcgt atcaattgct
    14461 ttaacgataa aatctatact cccatattcc gcaacaattt tttctaattc ttctaatgaa
    14521 gaaactttaa tagaaatagg tactacctga acatctgaat tatacttgtg tattttttca
    14581 gaaagaacat taatcttctc cttaccaaca tccgactctg tataaagaat ttgcctattt
    14641 aaatttgatg gttctattat atcgtaatca gcgacaataa gtttcctcac tccatacata
    14701 cttagactta aagatatata acatcctaag gctcctgctc ctaatactaa tactgtttta
    14761 ttctgtattt tattatactc ttcattataa aataacgaat agtaaccttt agttctagaa
    14821 tatctactat caatatctat ctcatccgaa attaaaattt gttcatttaa tagttcaaat
    14881 gttagtttac tgcctaatac ttcttctatc tctaatagtt ccttgatcgt tgataaattc
    14941 ttgcgaaatt tgaggttcta tagctatttc ccgcatactc cgaccacgta aatacattat
    15001 accttctttt ttataagcaa aaacataact atttacgtag aacatatttc gtccttccta
    15061 tcatatataa tatagaaagc agtatagaaa caaccacccc tcctatacta cgaacaataa
    15121 tattgggtgt caaaaactgt aatagttgac tcaaagggaa ataaataata acaaatgcta
    15181 ttaaaagttg aactatatat tgaaaattca agttattatt gttagaattc aagtatctta
    15241 aaataatacc actatcatac tgaaaaaaag gaattgaatt aataaaaatc atacctaagt
    15301 taatgataaa aaataagagt ccaagcaatt tatacgatgt gaacaataaa acaagtaaac
    15361 ctgtaagtga taaaatcgaa tttgaagcaa ttcctgctaa cataattttc aaaaattgtt
    15421 ttttattttt taggaattgc accccactta aatctacaaa aaaagccaaa ttaaacaaaa
    15481 gtagcattat tccacaattt gggatctcaa tttgataatt attagcaatt attgcatgac
    15541 taaattcatg tatcgttgca gatataataa caacaagcaa ccaaaataaa agaatgttta
    15601 gcgttattgg aaagttttgg aaattagtca aaatatccgc cctataaata tacataataa
    15661 aacattgcaa aataagagcc aatgggaaaa taccaaatag gattttttca aaattcttat
    15721 taaatctttt atagtttaat ttttcagata atgttatatt aaagtcccaa gatattttaa
    15781 aaatatttat cttttttcgt gatttcatag aatctataag tcccatttta ctaagaacaa
    15841 tataaaatct taaataatat ttcttcccta ctaacactaa taagtccgat atggtaaatt
    15901 cttgacctat tagttgctct aaccattttt ttcctgtttc ccaactaata catgtttctt
    15961 actggatggt atatatagat gatactgtcc ctcataagga gtaggtaata tcttaatctt
    16021 atcaacaatt ctcataacaa acctaacctt taataaataa aagaggggct aagtaaaaca
    16081 tactctagtc cctcagtccg caatcaataa aataatgact aattctatta atctcttgct
    16141 gcaagactaa tacggaaaat tcaaatgact gtctaaaatg aaattgaaaa agcttgatgt
    16201 tagtaaatga acaaacttca acaaccagca agagcaagga ttgctaaacc aaatccgata
    16261 cctgttgcaa gtccagctga aaaatcacta actggtactg aaatttcttc aatttcctca
    16321 aataaaaagt tatcttgcat gattatcact ccctatcttt ttaacaacag gctactccaa
    16381 ttaagagaac taccccagtt ccaagtaaaa cttcccccaa aaattcacca tctgtagggg
    16441 ctacgatttc ttcaatttct tcaaataaga atacttcatc tgacatatgt gttaccttct
    16501 tcatcaaaaa ttattttgta atcgattaca ttgcagatgt aacataaaga aaaacaaatg
    16561 tcaaatatta aacgtaaaaa catggtcact aaagaactat aagagaaaag gtaaacctag
    16621 cgacgcgatg aacgctgatt tgtttgattt cgattgctct cttcctcttg ttttttctgt
    16681 tcttcttctt gttttttctc agcttccttg gcctcttgtt tggctttttc ctcagcctcc
    16741 ataattaatt tatccgccac agtgtaactg taaattccag cttccatgtc gaccacactc
    16801 ggttctgaca attgtggctt aatcttactg taatatggca gtttcttact catttcagat
    16861 agaggaacca agacttcgtc cgaatcattc atggtcaatc gaattaaatc ggatgtcacc
    16921 ttgcttgggg ctaattccac cttttggata gccgccttga gttctgggct aatttgagca
    16981 agttctgaga caaaaacctt gatttgttca ctatcattaa agagaactga taaataagtt
    17041 tctggtaaac tgttcagact cacagaacta gtctcaagct gaccactgga aagaatagga
    17101 taatgatttt caccagaaat atagtaggcc acaatatcat attccttgac cttaatagtg
    17161 aacttagttg gaaattgata gacaagttga gctgattcaa cccaatagtt agacttaatc
    17221 tgcttttcat attttgcctt gtctagcaga aggttaatcg tataatccga atcctgaatg
    17281 cctgaagcct gtcgaatatc atcagctgta gtttgcaccg ttccctcaac acgaatatct
    17341 ttcatggtcg cataaggact gagcaagtag gcagagacaa tcaataaaag cagacttgga
    17401 aataaaatcg tgaaggctcg caagatatgg ataccaggaa tctttgcttt ggctggtttt
    17461 tcctttgtag cctttttagc aagcttttta tcctgttcct ccttctcttt agactctgat
    17521 tcttctttct cttctttctc tttgtcagcc tctgaggatg ctactttttc ttcagactct
    17581 tccttagctg attctgaatc ttcctggtct gtttcactct cctggtcctg tttgtcctct
    17641 gacttctcag attcttctcc catccgagct tgtctttcct tttccttctc ctcagctaga
    17701 gccgcttctt cttcagcctt cttttttaga tattcttggt ttcgtttctg ccattctgat
    17761 aactctttca attcttcgag gatttctttg tcctcatttt tcttatcttt tgacatttac
    17821 tttccttatg ataaatcttt tttcaacaat tgataaaaat ctgctagaga tttcaattcc
    17881 ttagaagctt tcatcttagc ttggtaatct tccttgtgac ttagtaagtg agaaagcttc
    17941 tcttccaaac tatccaaggt caaatcgctt tcttgaaggt cttctgcata gcctttctta
    18001 acaaagtaag ctgcattttc aatctggtca ccacgactag cttcacgacc aagtggcaca
    18061 atgacatgca attttgctat cgccaagagc tcaaaaatcg tattggcacc accacgtgtc
    18121 acaacaatat cagccaattc catcaagggt tgatagagat cggtcacata gtcaacacga
    18181 aaaagatttt ggctcaactc attcaggcta gaatctccag ttagattgat aatattgtag
    18241 cgctctgtta gttctttctt atggtctgtc accaattggt taaagacacg agcacctgca
    18301 gaaccgccaa caaacaatac agtcggcaat ttatgattaa agtggctttg aatatccacc
    18361 aattcatctg gttctggatt tttttgatcc gaaaccttgg tcaccgctcc cacatgctcg
    18421 accttagcca aactcgaagc ttgttcaaag gttgaataca tcttagtcgc aaatttatag
    18481 gcgattttat tggccaagcc catagacagg tcagattcgt gaataaagac aggcactcct
    18541 gacacacgcg cagcgataac aggcggtact gagacaaagc ctccctttga aaaaagggtc
    18601 tgtggacgaa gtcgcaacat gataaagagc gattggacga ttccccagcc aactttgaag
    18661 acgtccagca tattttgcca agagaaatag cgacgcaatt tcccagtcgc aatagaatgg
    18721 aaggtgacat ccaaacctga cttaaggatt tcttggtgtt cgataccacg cttgtccccg
    18781 atatagtgga cttcccaacc atcttcgatg aacttgggca ttaacaaaag attgagggta
    18841 acgtgtccaa ccgtcccccc acctgtaaag acaatttttt tcatatttta ttcttttaac
    18901 tccgctactg tgtcgataaa gaggtcgcca cgtacttcaa agttagcata catatcccag
    18961 ctggcattgg caggactaag aagaaccaca tctccttgag tcgcaagttc ataggcctta
    19021 cgggtcgcat ctgcaatatc tgtcgcctcc acataagcga caccagcctt gtctgctgcc
    19081 cgtttgacac gttctgcaga ttgacccagg atgaccatct tcttgagtcc agtaatgtct
    19141 ggcaccaatt cgtcaaactc attgccacgg tccaaaccac ctgcaatcaa gacgaccttg
    19201 ctgttgtcaa atcctgataa ggctttttga gtagccaaga tattagttga tttactgtcg
    19261 ttatagaatt taacaccctt gatgtcatcc acaaactgga gacggtgttt gacaccaccg
    19321 aaggctgaaa gagtttcctt gatggtttga ttgtccacat cacgaagctt ggctacagca
    19381 atagtcgcaa gggcattttc cacattgtgg ctacctggaa caccgatttc attcgctgcc
    19441 atgactactt caccacggaa gtagagttga ccatcttcca gataagctcc atcaaccttt
    19501 tcaagtgttg aaaatggtac aacagtggct tctgtcttgg aagccaagtc ttttgccaag
    19561 tcttgattaa agttcaagac aaggaaatca gctgctgtca tcttgttctg gatattccac
    19621 ttggctgcta catattcctc aaataatcca tgataatcga tatgagttgg cataaggtta
    19681 gtaataaccg caatctcagg atggaattct tgaacaccca tgagttggaa agaagaaagt
    19741 tccataacaa gcgtgttctt gtctgtcgct atttgagcaa cctgactagc tggatagccg
    19801 atattccctg ataaaagacc atgttgccca gcagcagtca aaacttcccc aatcatagtc
    19861 gttgtggttg tcttaccgtt cgatcctgtg ataccaataa tcggtgcttc tgaaatcaaa
    19921 taagccaatt ccacctcagt caagactgga attcccttgg ccaaagcctt ttcaatcatg
    19981 ggattgttgt aggggatacc tggatttttc accataagag caaactcttc atccaagagt
    20041 tccaaaggat ggccacctgt aatgaccttg atcccttctt ccagcaaact ttgggcagct
    20101 ggattgtcct cgaaaggctt cccatcattt actgtcacaa tggcacctag cttgtccaac
    20161 aaacgagctg cagattcacc agacttggcc aaacctaaaa caaggacttt cttattttta
    20221 aattgatcta ttactttcat gtctcgaact ccatttctac tcctactatt ttaccatttt
    20281 tatggaaata aaaaagccac aaagtgtgtt tgtgactctt tcttctagct gaatcttgcc
    20341 atatcatcta tgtgataaat cggtaactcg aataacttgg tccacttgtt cccaaataag
    20401 aggattgtgg gtcgcaataa taatagttcg attcggattt tttaaagatt ctaggatgga
    20461 aagtaattcc tcagagtttt tggggtctaa ggaagcggtt ggttcatctg cgaggatcaa
    20521 aggtggatcc tttaaaatta tcttcgctaa tgcaacacgt tgtgcttctc ctcctgataa
    20581 ctcaaatata ggttgcttca aatccaaata agagaggttt acacggttta gagcttgttt
    20641 catcaaagag attttctctt tttccttcaa ctttttacca actaaaccca gattgagatt
    20701 ctctttgacg gtttggcttt caattaagcc aaaatcttga aataagtatc ctaagtaatc
    20761 tctaaagaaa acagaaggct tgatgtcctt aagagaagtg ccatcataga tgatttgccc
    20821 tttgtcatat ggctctaatc gtccaatcat attcaagagt gttgtcttac cacagccact
    20881 tgtaccgatt aaggcataaa ttttcccacc ttcaaaatga agattcgtat ctgaaaatag
    20941 ctgacggctt ccaaattttt tagatatatt ctttagttca atcatcctat tttcctttca
    21001 taattgtcat agaaacacga gattctttct gcgcttgacg gtaaagcgtc agaactgcac
    21061 tagctagaaa gactaataaa gtgagcaagc caatcaccaa gtctcgactg cttaaaataa
    21121 aaagactagc accaaataca aaactggcaa attgactaac catatactga gcatgtgttt
    21181 caaaaaatcg taaacctgaa attcgtttaa tcaagatatc tcggcggaat tgctcgaaat
    21241 atagaagatt gacagaataa aatagtaaca aggaactagc tatccccaca atagctccta
    21301 agattaaagt tgctgtttca gtttgaactt cattataacg agttagataa acacttcttc
    21361 cttctttaag ataggatact tgctcataaa ttccagcttt cttcaaaagt tctagcccac
    21421 tctcatatcc tttgataaag agttgttttc cagcattgat agaccaacta gatagggata
    21481 taaaactatc acctgtagaa gtcggcgtga ataccactaa aatcggatca gtcaaatact
    21541 gagtggatac gggattctca ccgttattat aaacaaaccg cttttctccc attgaaagat
    21601 aactaacgtg cgctttcatc tcataatcca aaggagcact tgcctcctca ccagattttc
    21661 cataataact caatctttct tcaaaaactt tcttaagttc tgcttctcga gagcgcaaat
    21721 gttctgggag caagaggata aactcacctt tttggagatg ggctaacttc tgtttggtct
    21781 cagcatctac cacgaccttt tccttgtcca aataactggg actaacatag agcgtattag
    21841 catctggact ataggtatcc agtgtctctc cctgttcatt ttttccttgt ggattggcaa
    21901 aatggagcag attatccttt acataaagag cttgttcttc ttcgattgct tccttggcaa
    21961 aggcatacca cttgctctga ttttctgtat cttttcctct atcacctaag ccaaaagaaa
    22021 tttgataata gtctgctcta tcctgccatg cttgttttga aatttcaagt tctttcaatc
    22081 gttggtaaga cgtcaaacct gtcttaacag cgtatcctac tgtaaagaca gcaaccaact
    22141 gacacaatag ggttaaaatc atcaggcgtt taaggggtaa tctcccctta ataacgggaa
    22201 ctaatgcttt gtaattcaaa ctcattagat aaagaagcat tagtaaaatt gaaatcgcca
    22261 ataaaaacaa cagatagaaa ctaatcccaa aaccataggt ggctaacaag ataggataaa
    22321 acaaaccttg actaaaaaga acgactcccc cacctaggaa ggaaaggagg gctgatagaa
    22381 ggagccattt gatatcagta gataaagaat gccccatgat ggataagaga gtctgaccag
    22441 aaaagagttt tatacctgct gctctcattt ccttaatccg agtgataatc actaaagcaa
    22501 agaaagataa gccaaatatt gctaaactaa ttaaaataag gggatttagt aatattcgaa
    22561 aagcaagaaa atagggcggt atctttcggt cagcacttgc tttataaccc aaatctccta
    22621 atttatcggc aagcttttct ttcgtcaagg agcctgacaa aaggagataa ctatttagcg
    22681 gatcactacg ttcacgactt tcttggctag cttcttggaa ttcttttggt aaagttccct
    22741 gaccataagt tgcataagta aagtgagtcg tcccatcctt actcggctct acaattcttc
    22801 tagctattaa actctgttct gagtttgcaa aattctccaa ttcctgttca aatacctcac
    22861 gcgtcggttc ctgagtatct tttttgacac gaagtaaaga aacggaatca tagcttgcat
    22921 ataaatattg tggcgcacgt aagacaataa tccaagcaag gaagaagctg agaaaaaaag
    22981 ttgataataa tatgaatagt ttcttcatag tagactcctt gtaaacaaaa ttccccctgt
    23041 aatttcttac aaggggaacg atttaaatca atgaacgatt agtcataatc acagtaaaat
    23101 gctacttgtt ctccccattt agtccaaatc catgcatagg aggtttttcc agcaggagct
    23161 tctcctttat cagaatgacc atcccatctg ctcacgatgg atgaataatg atatttttta
    23221 ccatgatagt aatttgaaaa agcctaacca cctcctgaac cttctccata tgtccatact
    23281 cctccatctg gatattgtac agcagctgat gcagctccca ataatgtaaa atttgaaata
    23341 agagctagag caagtaatct atgttttttc gttttcattt tattttttct ttcaaaaaaa
    23401 gcacaccttg agcaacaatg caacaaaata aatcctcctc tctcttttat tgaaaccgct
    23461 ttcttatgtg ataagaataa cttttttatt atttgttgtc aaggaaaaaa tcgaattttt
    23521 tagatatttt actatattac ctctgtgaat aatattatat agtagtttta tttcaaaata
    23581 atatgcaacc agtactaacc aaatataaaa tagatgccat taacgaattt tattcaagtt
    23641 tttcccattc atactataca agtaaaagag atggtgttaa ctaaaaagca attcaaacta
    23701 ttgtaaaatt cctagcaaaa agagagccga aactctcttt tttatcttct tttacttttt
    23761 ttgactggca tgagtgtgat gtctctaaca ctaaagtaag ctaggatcaa catggctatt
    23821 gctaggaata tttctgttgg taattgaaaa attttcagaa aagatagaac caataaaatc
    23881 aagagtgcca ctaaaataca taccatagcg acgatattga cagtcccttt aatgctttct
    23941 ggtgtcgcaa atacatagag taggagcagt aaaattccta ggactaaata gaccatcttt
    24001 ctctctttct agctcttatt cagctgattt tttcttcttg ttagctttct cacgctctgc
    24061 tttgttaagg atttgtttac gcaaacggat agactcaggc gttacttcca tgtactcatc
    24121 gtcgttcaag aactcaagag actcttcaag tgtcaagata cgaggcgtct tgataacagc
    24181 tgtttggtcc ttagtagctg aacgaacgtt ggtcatttgt tttgccttcg tgatgttaac
    24241 tgtcaagtca ttttcacgag agttttcacc gatgatcatt ccttcataaa cctcagtacc
    24301 tgggttgaca aagatcgtac cacgttcttc gatagacatg attgagtaag ttgtagcctt
    24361 accagcatcg atagaaacaa gggcaccacg gtgacgtcca ccaatttccc ctggaatcaa
    24421 tggcaagtat tggtcgaagg tatggttcat gataccgtaa ccacgagtca ttgataagaa
    24481 ctcagttgag tatccaatca aaccacgcgc tggaacaagg aagaccaaac gagtttgacc
    24541 attaccagtt gaaatcatat ccaacatttc acctttacgt tcagaaaggc tttggataac
    24601 agacccttgg tattcttctg gagtgtcgat ttgtacacgt tcaaatggtt cacatttaac
    24661 accgtcgatt tcttttacga taacttctgg acgagatact tgaagttcat agccctcacg
    24721 acgcattgtt tcgataagga ttgacaagtg caattctcca cgtcctgaaa cagtccattt
    24781 atctggtgaa tcagttgggt caacacgaag ggaaacgtct gtttgcaatt ctgcctgcaa
    24841 gcgttcttcc accttacgag aagttaccca tttaccttct ttaccagcaa atggtgagtt
    24901 gttgaccaag aaagtcattt gaagagttgg ctcatcgatg tgtaggattg gaagagcttc
    24961 tactgcatct gtcggagtga tggtttcacc gacaaagatg tcttccatac ctgaaacggc
    25021 aatcaagtca cccgctttgg cttcttggat ttcacgacgt tccaaaccaa agaaaccgaa
    25081 gagttttgta acacggaagt ttttagttgt accgtcaagt ttagaaaggg taacttggtc
    25141 cccaacctta actgtaccac ggaagacacg accgataccg atacgtccaa cgaagtcatt
    25201 gtagtccaaa agtgacactt ggaactgcaa aggctcatct gagttatcta ctggagctgg
    25261 gatatggtcg ataatcgtgt caaagattgg tgccatagtc gcttcttggt cagctggatc
    25321 atctgacaat gaagaagttc cgttgatcgc tgaagcataa accactggga aatcaagctg
    25381 gtcgtcatct gcaccaagct cgatgaaaag ttccaagact tcatccacta cttctgctgg
    25441 acgagctgat ggcttatcga ttttgttaac aaccacgatt gggacaaggt cttgttccaa
    25501 ggcttttttc aatacgaaac gagtttgtgg catggttcct tcataggcat ctacgaccaa
    25561 gacaacaccg tcaaccattt tcatgatacg ctcaacttct ccaccaaagt ccgcgtgtcc
    25621 tggtgtgtcc ataatgttga tacgagttcc gttgtaagca acggcagtat ttttagcaag
    25681 gatggtaatc ccacgctctt tttcgatatc gtttgagtcc atagcacgct ctgccaattc
    25741 agtacgtgca tcaagcgttt ctgattgttt caataattcg tcaaccaggg ttgttttacc
    25801 gtggtcaacg tgggcgataa tcgcaatgtt acggatatct tctcttaatt ttgtcatgat
    25861 ttcctctata atattcaaaa tttattttct aactgaacga ttataccata atttcaaata
    25921 aataacataa ctcaagcaag tgtaaatgtt ttcactccgc ttttcttttc acgtcaagcc
    25981 ttttcaaagc aagcgactta tgataagata ggcacagtat gcgtttagat aatttattag
    26041 cccaagaaaa agttagccga aaggccatga agcaagcact cctcagaggg gaaattctag
    26101 tcgatggttg cccagcccgc tccctagctc aaaatatcga tacaggacta caagaactcc
    26161 tttttcagga tcgaatcatt caaggctatg aacacaccta tcttatgctt cataaacctg
    26221 ctggtgtcgt tacagccaac aaagacaagg aacttccgac cgtcatggac ttgcttccat
    26281 ctgacatcca gtctgacaag ctctatgccg tcggccgact ggaccgagat acaacaggac
    26341 tccttctctt gaccgataac ggtcccttgg gcttccaact cctccatccc caatatcatg
    26401 tcgataagac ttatcaagtt gaggttaatg gacttctaac acctgaccat atccaagcct
    26461 ttcaaaaggg aattgtcttt ttagatggta ctgtctgtaa acccgcaaaa ctagagattc
    26521 tatctgcaag tccctccctc agtcaagcct ctatcaccat ttcagaagga aaatttcatc
    26581 aaatcaagaa aatgttcctc tcggttggtg ttaaggtgac tagcctcaaa agaatccaat
    26641 ttggggactt cacattgaac ccagatttag cagaaggtaa ctaccgccct ttgaaccaaa
    26701 aagagttaca aatcattaaa aactatttag agatgagtcg ataaaacaaa aaaagcttta
    26761 aaactaaagc ttttttcttt tatttaccga aaaattaagg cgattgctac aatccagtta
    26821 actacagaaa tcacaattcc taagatatta agaatctttt ctattttata ctctaattgt
    26881 gactcttttt ggtatgaaat agccaagacc aatcctatga tacccaaaat caggcctaca
    26941 attggaaata acaaaccaag aataatcgac aagataccca caaaaagtgg atttttcttc
    27001 ttttctttca tgttctaaga actctttaaa ttttatacaa attaattata ctataaaaca
    27061 atagcttcat cctatcattc gactaatttg gaaataaggt tagctagtct tcactttccc
    27121 tttccaagaa tccaagccat aagaaaggat ataaatctca gaaaaacctt gttttttcaa
    27181 gtaaagagct gcatttgtaa ctcgttgcgc acgttggttc tcgtagagaa ggacaggttt
    27241 atctttacga agggctgcaa gactagtttt caactgactt gaaggaatat tgcgtgcacg
    27301 aaggatatgt tttctgtgga attctgctgg gtcgcgcaaa tcaatcaatt gacccgtacg
    27361 aatcaaggct tcaaactcct cattgtccac aattttagcc gcacggcgaa tacgaagata
    27421 gttaaagccc atccacgcca acattgctag tataagtgcc cacaaaatcc aagtaaccat
    27481 tagttctttt ctccattttt ctcaatataa tccaattcta ccttgtgctc tctgcgaaga
    27541 actgcttctg cctctagata gtctaattta tccatcaacc ctgcatcgta aatccgagat
    27601 agttccaact tcatcagttc aatatcatat aagcgttttc ccatgtaaac aataatacca
    27661 aatcgtttga ggaattgctg cacatcatag aatgttttca taagactcat tctagcaaaa
    27721 ttttgtgttt ttttcaagaa gagactcaca caatgctcct tattttccta tcttctttgg
    27781 cgattctaag gcaagtgtgg tacaataaaa acatgagaat tcaacaatta cattatatta
    27841 tcaaaatcgt cgaaactggc tctatgaatg aggcagccaa gcaactcttt atcactcagc
    27901 ccagtctctc caatgcagtg cgagatttgg aaaatgaaat gggcattgaa atctttatcc
    27961 gcaatcccaa gggtattacc ttgacccgtg atgggatgga gtttctctct tatgcccgtc
    28021 aggttgtcga gcaaactcag cttctggagg aacgctataa aaatcctgtc gcccaccgcg
    28081 aactctttag cgtttcgtct caacactatg cctttgtggt caatgccttt gtctctttgc
    28141 tcaagaaaag cgatatggag aaatacgaac tcttccttcg tgaaactcgg acttgggaga
    28201 ttatcgacga cgtcaagaac ttccgcagtg aggtcggggt cctcttctta aacagttaca
    28261 accgtgatgt tttaaccaag atgctggatg acaatcacct gctatcccac catctcttca
    28321 cagcgcaacc gcatatcttt gtcagcaaga ccaaccctct ggcaaagaaa gacaaggtga
    28381 aactgtctga tttggagaat ttcccttacc tcagctatga ccaagggacg cacaactcct
    28441 tctacttttc agaagagatt ctttctcaag aacaccacaa gaaatccatt gtggtcagtg
    28501 accgtgccac cctctttaat ctcttgattg gtttggatgg ttataccatt gcgacaggga
    28561 ttttgaacag caacctaaac ggagacaata tcgtttctat cccactggat attgatgacc
    28621 cgattgagct ggtctatatc cagcatgaga aaaccagcct atctaagatg ggcgaacgct
    28681 ttatcgacta tctactagaa gaagttcagt ttgatagttg agaaatgata agaaccaata
    28741 tgtaggctag caacaacctg cacattggtt ctttttactt ataattaaaa gtttcccctg
    28801 ccaacttatc agctagcttg ggaaagagag tataaaactt atgggctagg ttcaacaaaa
    28861 tcgggagatt gagttctcgt ttattttttc ctataatctt gacaatcttt ttagccactg
    28921 catctgcctc taagaggaag cggtcaaccg atttaagata agttccatct gggtcagctt
    28981 ggtcaaaaaa tcctgttcgg attggacctg gattgactgt tgtcacatag actccatagg
    29041 gcataagttc gagtcgcaga gcatttgaaa aaccaatagc cgcaaacttg gtcgctgagt
    29101 aaagactaga cttgccagta gctattagac ctgccatgct gacgatgttg atgatatgcc
    29161 ctttgctgct ttccttcata cgagccgcaa ggtgacgaga cagattcatc agggcaaagg
    29221 tattgacctc aaacatctgg tgaatgtctt tatcagcaat ctggtcaaat ccctcaaaaa
    29281 tcccgtaacc agcgttgtta atcaagacat caatcttgcc atagcggaga taaagatcag
    29341 ttaccagagc ttctagggct gaatcgtcgg taatatcaat ttcaatcaat tctgcatggg
    29401 aataatttcc gtagagttgg gctaattttt ccttatttct accaagcaag atgagttggt
    29461 cattgggcag gagtttgacc atttcttgag ctagaccacc gctagctccg gtaatgagaa
    29521 tagtaggcat acttatcctt tctgtgactg ctagatttcc acttcttcca agtctttgac
    29581 cacatggaca ttttcaaaaa ttgtggcagc gtctttcttg agtttgctaa tatcttttga
    29641 gaggaaacgg gcactgatat ggttgagtag gaggcgtttg gcacctgctt ctaccgctac
    29701 ttgtgcagct tgcatattag ttgagtgacc atggttacga gcaatttttt catcaccctt
    29761 gccataagtg gactcatgaa ctaggacatc tgcattgaca gccagacgca cactagcatt
    29821 ggtttttcta gtgtctccta aaatagtgat aatcttacct ggacgtggcg ctgagatata
    29881 gtcagccgcc ttgatttcag ttccgtcttc caaaacaaga tcctggccgt ttttgatttt
    29941 accaaaaagc gggccgaacg gaacaccagc agccttgagt ttttcagcat ccagcgtccc
    30001 ttctagatcc ttttgcatga cacgatagcc aacacagaaa atagtatggt ccagctcctc
    30061 tgcatacaca gtgaatttat cggtctcaag gatttttcct agagaatctt ggtcaaactc
    30121 atggaaatga atgcggtagg gcagacgaga acctgacaca cgaaggctgg ttaagacaaa
    30181 tgacttgatt ccttgaggtc cgtagatttc caaatctgtc tgctcttcat tggcctgaaa
    30241 ggcacggcta gaaaggaaac ctggcaaacc aaaaatgtgg tctccatgca gatgggtaat
    30301 aaagattttg ctgatcttac gtggtcgaac tgtggtttcc agaatgcgat tttgcgtacc
    30361 ttctccacag tcaaagagcc aaacttcgtt aatctcatcc aaaagtttca gggcgagact
    30421 tgaaacgttg cgagctttag agggctgacc agcccccgtt cctaaaaatt gaatatccat
    30481 tcgatacttt ctaattaatc aatatataac atggctgtgc ggttttccga tcggaaatag
    30541 cgtttgccag aaaaagcagc agcttcttgc aataaatcct cttggctgta gcctttgaga
    30601 cgttttcgac catcagccaa tctttccaaa tcagtcaaag ctgtgagact ttctaggctg
    30661 acaacttcct cgtcctcgac aggcttcatg taaatcttac cagactcttc aaagactaat
    30721 tgatggggga aaatttgcgc aatttcaaag agcaagtcat ccgagatttt ctcctcattt
    30781 tcagagaaaa tccgaccaag gccgtcacta tcataacaaa aaccaaagga tttaccagac
    30841 agattaagcc gaataaaagg cttattttct agggtgaaac ttggctcagt attgtaaaga
    30901 ttcagttcct gactgagttc tgcaaaataa tccgtcgcag cctgaggact ctttttctga
    30961 tagagttctg caaagtaggc attaacaaca cttggcggag gtgtaataag tgttaactgc
    31021 tcctgctctg ttttaccagc tagaagctga accagataga ccttgtccag acttgtataa
    31081 cctccatact ttagagccaa agctttaata tcagtcataa aattcttcta acctccattt
    31141 atttttttcg gaaatgtagc ctgtaatcac ttcgctgtct tcctgataat cacgttcttc
    31201 cagaattgca acactctcta aatcatgaat cttgtaggac tttgaaaaag gcactcgcag
    31261 ggtaaatgct tcaaaaattt ccttaatctt atctagcaat aatgcttgca agttttcacg
    31321 actgtcctca gacttggcag aaatgagggt atatggcgtt tgggtaggcg tgaaatcctc
    31381 caccaaatcc gctttattat aaagcgtcaa gtgaggaata tcttccatgt ccaggtcttt
    31441 catgatggag agaaccgttt tttcatgctc ctcgtggtaa ggattgctag catcgataac
    31501 atgaaccaga aggtccacat gcttgctttc ttccaaggtt gacttgaaac tggacaccaa
    31561 ctctgtcggc aaatcttgga taaagccaac ggtatctgtc aaagttactt ggagattgcc
    31621 tcccagatga atactcttgg ttgtcgcatc cagagtcgca aagagctcat ctgcttcata
    31681 ctgggtctta ctggtcaaga tgttcatgat agttgatttc ccagcattgg tataaccaat
    31741 caaaccaatc ttaaaagtgc tagactccaa acgtttttct ctgacagtcg cacgattttt
    31801 ctcaaccacc ttgagctggc gctcgatatc cgtgatttga ttgcgaacgc tacgacggtt
    31861 cagctccagc tggctttcac caggaccacg ggaaccaatt ccccctgcct gacggctgag
    31921 cataatcccc tgaccaacca agcgaggcaa aaggtatttg agttgggcta ggtggacttg
    31981 gaacttccct tcatggcttc gagcccgcat ggcaaagata tccaaaatca actgcatacg
    32041 gtcaatgacc ttaacaccga gaacttcctc tagattgaca ttctgccttg gggtcagacg
    32101 gttgttgacg atgacagtag tgatttcttc tgcatccacc ataagcgcaa tctcttccaa
    32161 cttaccagag ccgacgaagg tcttggaatc atatttttca cgtttttgtc tgtagctatc
    32221 tacaacgact gcccctgccg ttttcgctaa actagccaat tcttccatgg agaggtcaaa
    32281 actgtccata ccctgcaatt ccacaccaat cagcaggact cgctcctctt ttttctccgt
    32341 ttcaatcatc taaaaactcc tctatctggc ttaaaatgcg gtcttgtaca ccagattctc
    32401 caatctgata aaaggtgacc tgcatgcgat tacggaacca ggtcagctga cgcttggcaa
    32461 aacgacgggt cgcctgttta agactctcac tagcttcctc aaaggtctgc tctccacgga
    32521 aataaggaaa gagttcctta tagccaattc ctttagcagc ctgtacatta ggggaatggt
    32581 caaacagcca cttggcctca tccaaaagcc cagcctcaaa catcaaatcc actcggtggt
    32641 tgatacgctc ataaagttga ctacgttcat catccaagca gataatcagc ggttcataca
    32701 aggtctcttg attttccaaa tcctgaccaa aatgggcaat ttctaaggca cgcatagcac
    32761 gacgacgatt aaactgggga atctcaaggc ctgcttgctc cacaaaatgg gctaattcct
    32821 catctgaata cggctccaaa ctagctcgat aagctaaaat ctcctcatga ggagtctccc
    32881 cacctaggtg gtaaccttct agcaagctct ggatataaag tccagtccca ccggcgataa
    32941 tggctagctt gccacggctg tgaatatcct caatagtcat cttagcttct gaaacaaaat
    33001 caaaagccga gtaagactcg gttatctctc taacatcgat taaatgatga agaacagctg
    33061 cctgctcttc tggactagcc ttagctgtcc caatatcaag tcctcgatag acttgttggc
    33121 tatctccact aaccacttcg ccattaaaac gctttgcaac ttcaatagct agagccgtct
    33181 ttccaacagc agtcggtcca acaatcacaa ttatttttgt tttcatcttt tttccttgaa
    33241 aaattcccat tttttcgtta ctattattat aacacaaaaa ggtcagtcag aaaaatgtga
    33301 cctcttgagg aggctggctg attgagaata taaaggagga agactcatgg ctaaaggatt
    33361 cgctaaaggt cttgtaacag gtgtcgcagg aactgtcgct gccgttgcag gtgcagtata
    33421 cgcatttaaa aagaaagtaa tcgaaccaga agagcaaaaa gcagctttca tcgaagaaaa
    33481 ccgtaaaaaa gcagctcgtc gccgagtatc acgttaagaa acaaaagaag ttgggattat
    33541 tctcaacttc ttttttctat tcttttaaat agctaggtca aacttcaact gtggcttaac
    33601 agggtcataa tccaccaact caaaatcttc tgctttgata tcaaagaaat tagtcccatc
    33661 aggaacattt aaaaccaagc gtggttggca gtttgacggc tcccgacgga gcaattcctg
    33721 agcttgttca aattgattat catagatatg gaggttgttg atgaagtaga agaacttccc
    33781 aaccttccag ccaaaatgtt tggcaatcat catctgcaaa gccacatact gcatagcgtt
    33841 gatgtggtgg gccaccagca tatcattcga gcgctgggtc aaggtcgcat ccagatagat
    33901 ttctccatct atacggcgga catcaaacat ggtctgaaag gcgcacggga gcagcccatc
    33961 tgtttcttcg aaagcttggt aatcccagag cgaaataata ttgcggcggt tccaaggatt
    34021 ggtttccaac tgtttgagaa gcttattgat aatgtcgtgt ttcttaacaa cggcaccata
    34081 gcgctcacca atggttcccg tgtctccaac ttcccagtca ttccagtagt gaacattgta
    34141 cttgtcatta agcacttcta agctatttga ctggtcttgg taaatccaga gaacttcttt
    34201 gatggcggat ttgattgcaa tgggacgcaa ggttgtgata ggaaattctc ctttagataa
    34261 gtcgtactcg gaaaaggcac cagttacata cttggaatta gcaacagtcc catccttgta
    34321 cttaggacga gcctgctctg agaaaacacc ttcctttaga atgcgttcaa tattctcttt
    34381 aaaaatcgta tctgcttttg tcatttcgtt tcacctcatt cattgtccta actagtatag
    34441 cataaaaaat aaaagaggaa cattactaac tctaggttag cattttcctc tctcattatc
    34501 ttattgcaat acaagtgatg ctgctccgat aactccagcg tcatttccta gagttgcaag
    34561 agctaattta gtagatgtgc gtacttgtgg gaaactattt tcatcgtaaa ctttttgaac
    34621 accttgtaga aggaattctc ccgcagctga cacaccacca ccgatgacga ttgttgatgg
    34681 gtttaggatt gaaccaatgt tagcacaagc gattcccaag taacgtgaga agttacggta
    34741 aacaatcaaa gcaaggtcgt ctccttcttt tgcgagatca aagacagtct tagcagttac
    34801 ttcttctccg ttatcaatca agcgtttcaa ggctgcatcg ccttcgtatt catcggcata
    34861 gcgacgagtc aagttgacaa tccctgttgc tgaagcaact gtctcaaggc agcctttttt
    34921 accacaagta catgagattg gttggtcaaa gtcaacagtg atatgaccaa gttcacctgc
    34981 tgcaccagca acaccatgaa gcaatttgcc ttctgcgaca ataccaccac caacaccagt
    35041 accgagtgtc ataaagacaa cgtctggttg gttatctcca gcacccatcc agcgctcacc
    35101 aagagctgct acgttggcat cattatcgat gaaaaatgga atgcccaaag ctttttcaat
    35161 cttttgtttg attggttgaa gggttttcca gttcaagttg taggcaccga taacagtccc
    35221 tttgtcacgg tcaaccacac ctggtgatcc cattccaatg ccttggaagt ccgctgctgc
    35281 caatccaagc aagtccaaac gatgttgaat agactcaatc atatcatcaa cgatatgact
    35341 tccctcatcc aaaatgttgg tcttgattga ccattttcct tggatttctc ctactgttgt
    35401 taagattgca aatttgatag aagttccacc aaggtcaatc ccaataatct tttgactcat
    35461 catattctcc tttttcattg tgtagtaatt gaaaatgctt acagtactag tatatcaaaa
    35521 tccattcact tatgcaaagg tttgcgtaaa tgaattataa ggaatttttt cgcctaccag
    35581 tatctgttaa tcatctaaat gatcaatggc atattgagct gcatcatttg aaaatttatc
    35641 aaaatcagaa gttaattgtc tatacatacg tttttttgac atgtggaata acgaattata
    35701 actttttgcc tttcctaaag cagcagaata ttcactattg ctatcattac tagaagaaac
    35761 tgtacttgct tgaccttcct tccaaactcc gtcagcgcca acataataac gtccaccatc
    35821 aacccattca ttgacagcca ttttaccatc cgattttaga tagtaatttc cttgccatgt
    35881 actgtaagca taagaaccat ctgatgtcaa ataataccaa gcttgatagg tggcatcata
    35941 aacccattca cctttagcca ttttaccatc tgatttcaaa tagtagtttc cttgccatgc
    36001 attgcgagca tatgaaccat ctgatttcaa gtaataccat gcttggtaag aagaatcata
    36061 aacccactca ccttgtgcca ttttaccgtt tgatttaagg taataagctc cttgccatgc
    36121 attttttgca taagaaccat ctgatgtcaa ataataccaa gcttgataag aagagtcata
    36181 aatccattca ctctgtgcca ttttaccatc agctttcagg taatagcttc cctgccatgc
    36241 atttttcact agatttccat ttccatcaaa gtagtaccaa gcgccgtcct gcttaaccca
    36301 accacttgtt gttgctgaac ttgtgttgat ttgaatagcc gttgactgtt ttgctttaaa
    36361 agcaccctta ggagcatttt tcaattcgca agccacacca tcatgatcac ggtctaactt
    36421 ggcagaataa ccaggttctc cctcgtgaat atccgaatag ccattcgccc aagcttcctt
    36481 acagctcgaa aaatggatgt tttcttccgc caaaactggt tgtgaaaaca aggctaaaat
    36541 tggcaacgtc accagactca tttttaaaaa tagacgttta ttcatttctt tctcccataa
    36601 ttatgatatc gatttcaata ttattttatc aaacttattt cagcaattca aggaaacttc
    36661 tggtcttttc tacaaactcc tttggttttg ccttattcaa gacatgaggg ccatcaggaa
    36721 tgatctgaaa ctgcgaatct gttaacagtc tatggagagc tttcatagaa ctaagattcg
    36781 gtttatcttt gctgccacaa attagtaagg ttggatagga gcaagtccct gctatatccg
    36841 ttaaatcaag tgtcttcaat tcctcagaaa ctccgaccat aagagtcttg tctgctccct
    36901 gtttttcaaa tactcttttg ggaagtagtt taaaaatcag caactgaaga taaaatagga
    36961 tattccctgc taatttaagc gggcatcctg acagaatcaa agctcgaaga tttggtaaat
    37021 cgtaactgga aagttctagt gtcagggcag cacctaagga caatccaatc aaaacaaaag
    37081 gttctgtctc ttgagctagg tgctgataaa ctcgctcttt agcttgttga tagttactaa
    37141 ctccagaagg aaataactcg atagcctcag aaggataatc tgtcagtaga ttccgaactt
    37201 ctttccaaga ctctgctgac tgccctaacc catgcaaaaa tatcaatttc atctagttct
    37261 cctcaaggct tagttcatac aagcctctca ctgcattaca gccgtaaata gcttctgctt
    37321 gggttaaatc tgccaaggtc aagactttct cttctacctg tcctgtttct agcaaatgct
    37381 gacggtaaat tcctggcaag attccaagtc ggataggcgg tgtgtagagt tttccagcga
    37441 ttttcagaac caaatttcct atagaggttt caagcagttc tcctgactta ttgtggtaaa
    37501 tcttctcttg ttctcctagg ctcaaatgcg gtcggtgagt ggttttaaag taggtaaagg
    37561 attgattcaa agcagcttcc tgaaggcaga cttgggcctg acaaaagctt gtactgagag
    37621 gggttaatac ttgacgattg acttctatct ctccagattt gctaaggctg attcgcaagc
    37681 ggtaatcttg attagcttca caatcctgac actcttcctc aatcttgtgt cccaagtctt
    37741 ctgcatcaaa aggaaaggca aaataacgac tagcttttct cagtctttcc agatgttgat
    37801 cttcaaacag caggttcttc tggctgattt cccctgtcgt aatcagttgg aagcgagctt
    37861 gtttacgata aagaactgct gccttttgat gaacctctcg gtattcagat tcccatgtgc
    37921 tatcccaagt aatccctccg ccaactccat aaatggcttg acctttgtga agttgaatgg
    37981 tacgaatggc cacattaaaa atccgtcgtc catttggaag caagagacca atcgttccac
    38041 agtagactcc acgcggttga ggctccaagt tcttgataat ctccattgtc gcaattttcg
    38101 gtgcacccgt tatggaacca caaggaaaga gtgagcggaa gatttcaaca aggtccacat
    38161 cctctcgcaa ctgactcttg atggtcgaag tcatctgcca aacagttgaa tactgctcta
    38221 cctggcacag acgctccacg tgctcgctcc caacttcaga aatacggttc atatcattgc
    38281 gcaagaggtc cacaatcatc atattttcag agcgattttt gggatcctgt tccaaccaac
    38341 tggcctgttc aagatcttct tggtcagtta ccccacgctg agtcgtcccc ttcattggtc
    38401 gtgttgtcaa ctcgcgatca ttttgctcaa aaaagagctc tgggctcatg gaaatcactg
    38461 ccatctcgtc atgttccaca taggcattgt agcccgcctc ctgctctacc accatacgat
    38521 tgtagatggc aaaaggattg gcacttaact tttgcttgag ttggacggtg tagttgacct
    38581 gataggtgtc tccctgcctc aagtgatggt gtatctgggc aatggccttt tcatagtctg
    38641 ctgcagacgt tacttcctgc caatttgagg gcaaatcaat atcctcataa gtcagaggaa
    38701 taggggaagt ttctacgcta tcatgaacag taaaataaag caggtactct cccagtaggg
    38761 gatccttgtg aactgctaat ttttcctcaa aagcaggtgc agcctcgtag ctgacatacc
    38821 ccaccacata ataaccttgc tcttggtagc tttccacttg tgccagcaaa tctgccactt
    38881 cttctacatt tctcgttttc aactctttaa taggctgggt aaaggtatat ctctccccta
    38941 aagtcctaaa atcaatcact gtttttctat gcatacctta agtatagcat aaaataagaa
    39001 aaccctcatc cgcaaagcag atgagagatt tcgattatct aaagatagaa gttttaaagc
    39061 tatctgtttg ttgaagaagt ttcttataaa cagcttcttt tagttttact gtattagtca
    39121 tagatactgt tttgtgaccg tttgcttctt gtttaagagt ttcagcatct tttttaacag
    39181 cttctttaaa tagtgtaagt aaatcatcgt atgatgaaac ggaagaacca tttacttcga
    39241 atgttgttaa tcctttcgtt gctttatctt taacttcttt gaaataagct tttttaaatt
    39301 cttcaatagt gttgaatgta ttattagata ttttcttgat aatatattca tcacttagaa
    39361 ctgactcgcc atcttttgta gattgttgtt tatatttatt cgaagtatag cctaggaatc
    39421 cgttaaggta tccgtagtaa ccccataatc taaaggcgtt atgtttgaat gaaacagctc
    39481 caggagcacc tttactagta ttacctccgt agataccggc tgtcatttca acccccacat
    39541 aaggtgattg atcgtattgg ctaacgactt caggtttata aacacggttt ccaatttgtc
    39601 tattagtcat taactgttga tctattaaac tatcaattga tgtaatattt aagttatctt
    39661 tttcttcagt tgttagattt cgaatttcgt cccactgatt taattggctg gcatctcgga
    39721 atttcttatc tattttcttg aaccatgctc catttaactc tttattattt tgattaataa
    39781 cagcatctgc ctctaaatga tcgacaagca ttaaagcatc attgtaacca cgcatatatt
    39841 tatcgatatc atcacgtgtt gtaagagatt taggatctgt atcgtaccat tgattaccat
    39901 cattaggttt tttgaatacg gtattcagac ctaatgaacc atattcgtta aatccacttc
    39961 ctgggactgg tagttgtaac ataccttgag caaatgcttc agcatcagta ccttcacgac
    40021 gtccaaaacc acccaaatag attttacgat cgtttatatg tgttgtttca tgagtataca
    40081 cagaaatacc ataatcccca atcatattta gagcaacata acttacatca gaacgaggat
    40141 ccattggatt atcataaagt gcagcatatg ctcctgttcc attataacca taatattttt
    40201 ctataggtcc aaagaattct ctaagaggag tatatacatt gtcagtatta tatcgaccgt
    40261 atttttcaac ccagccacct ggcgcattat aaccttccca gataggaatc acagtatctc
    40321 ttagtagata ttgtttaaca ttatctggaa ctagacgata ccaaaaatca tagtagtttc
    40381 tgtacccatc agcagcataa tcaacagatg ctttaatgtc ttctaatgat ttttttccta
    40441 atttctcagc actaccaatt gcaattgcgt tgtagttaga ggcaataaac atgtgtgatt
    40501 tagttatatt caataatggt aaaatcattt ttctgtgctg agctacgttt aagttagcat
    40561 atgctctata tttagcattt ttaatttctt cgacctcaga tgcgcgttct gcgatgtaga
    40621 catggtcttt tgtagcatca ataaaccaat cattcatatt atctatattt gtgaataatt
    40681 gtctattata atttaagaat acatctaaat tacctgattt agtatattta gctaatactt
    40741 caccgaatgc gtcgaatgta cgtgaacctt taatgttgtt ctctttagag ccgatttcaa
    40801 ttaatctgtc taatacgcta actttttcac catagaagtc tggtttgaat aacattaatt
    40861 ctttaatatt aacatcaccg aatttaacac cgtagtaacg gtttaagtat gttaaaccta
    40921 ataatagggc agctttgttt ttctcgactt tatcacgaag catttgacga gcagctggag
    40981 aatcatttaa ctggtgttct tcattttgaa ctaattttgt gattaggttt gttaagttct
    41041 ttttaacggc tgtgaagctt tcttctaaat ataaatcttt gattgcatta actctatagt
    41101 cacctaatcg atttaggtgt tgatacattg tttgagattg aagatctact ggttctaaaa
    41161 tagattttat gtcattaaca agagtagtgt tatctttttg cacgatattg ggtgtatatt
    41221 taattcctag gtcagttata gtatattctt ttacattact taaaccttca ctgctagaag
    41281 ataagttaaa gtaatctttt gtaccgtctg catagtgaac aataatttta ttagcttcat
    41341 ctaggtttgt gataaactca ttgttgttca tcgctgtaac agaaaggact tctttagtat
    41401 ttagagggtg ttctttattt aatttattac cttggtatac aatataatct ttattgtaga
    41461 atggtattaa tttttcaagg tttttatagg cttgattata ttcagcgttg taatcttgaa
    41521 tactagaata agctttttct tcattaagtt ttgcaagagg agatagctca ctttctaatt
    41581 tatcagcagt aatattgaaa gtagcaactt tagcatcagc ttgttcttta gttaattgtt
    41641 ttattttttg cagattggta aaattattag ctccactgct agcgccgttg actctataaa
    41701 tatcagataa gaattggcgt gcatctccgt cattaatttc gtttgaacca tatacttctt
    41761 cacctttaat tactttagca taggtaacaa tatcttttat aactccccaa ggccaagttt
    41821 tagctacaac accaccaaca aaacgagtat ttttaacatc taaagttcct ttagcaaccg
    41881 aattggtaac ttttgactta gttccatact gatagctatt taacatatat gtaaccaaag
    41941 gaactagcat acttgcgctt gcgttagcgg cagtaatgtt agcatcaaca taagctttat
    42001 taacaaatcc catgtagttc gaaccagcaa ttcctccgac tgtagaatta ttaccaacag
    42061 aattgatatt acctataaat gctacgtttt ctagagcagc attttctttg atattgttta
    42121 caaatccagc aacgttattt ctggctgtta tcgttccagt tgctttgatg ttttctatac
    42181 gtgtggttcc gttgatttca ttcgcaattg tcgcgatatt atcttgatta gacacattaa
    42241 tatcaatatt ttcaaaattt atatttttaa cagttccagc tttaatcttg tcaaataatg
    42301 gatgttccaa ttcagtaata gcaaattgtt ttccttcaga acttaaaagt tttcctgtga
    42361 attctttagt gatatatgat tttccattag gaacaacatt tctagcgctc attgattgtc
    42421 ccagacgata ttcttttgaa ggatcgtttt gaatagcttc cactaattct ttgaaattat
    42481 aatatacatt atcttcgtgg actttaggtt tttcaatata gtgaacgtat tcttcttcaa
    42541 atttattatc agcagttcta gagactaaat tgtctgcgat tgctgtaact ttatatacat
    42601 gtgttccgtt aaccgtagtt tcttctatat ttttaacagc tagtaatgta gttttctgat
    42661 tatttgaagt tatttttaaa taataattgc tcttatcatc aggaatagtt gttatcagtg
    42721 attcattagt ttcttttcca ttttcgtatt tgattaaatc tgtacgttta atatttttaa
    42781 gctcaacttt tttaagatct aattgaatat tttgattttc tagagtttca gtttcttcac
    42841 cgttacctct gtcgtaaatc atagttgtag atagggtgta ttctttgtag tactctaggt
    42901 tcttaaatgc agcgcttata gtttctgttg ttaccttgtc atctgtaaga actacagtat
    42961 taataacttc ttctcctttt ttcaattcag ctgtgattga tttgattttt gttttgtttt
    43021 gattttctag agtatactta gcaacagctt cacgttccaa tattttctta tcggtactag
    43081 tcaatgttaa tattggcttt tcagataatt caaccaattt ttcaatagtt gcagttaatt
    43141 tttcaacagc ttcgttaact tcactttgtt tagcatctgt attagctgca actttttcag
    43201 cctttgtaac ttcagtttgg aggttttgcc aacttctatc actgtaatgt tcttttacct
    43261 ttgtttttgc atctgcaatc gtattgttta attcagtttt atcaacgttt agagcgtcaa
    43321 tagccgtttt aagtttattt gtctcgctat ttacctcagg ctgttttaca ggctctgaag
    43381 catagacacc ttttgcagtt tctaaaacag gtccaagagc attgtaactt gctgtagaat
    43441 aatcagtagg agaaactgaa ctagctttat caatttgatt atttaactca cttttatcaa
    43501 ctggttcttt agtaccaata ccctttattt tatcttctgg tttcggtgtt tcctctacag
    43561 ccttctcttc ttcaggaact tctggttgct tttctggctc aactggtgcc gttggtgcct
    43621 gttcgtcttc tcttggcgcg actggttcac ctgcttgttc aacttttggt tcctctgttg
    43681 gttctgtttg tttttctaca gcaggcgttt caacttttgg ttgttcaata gattgattaa
    43741 cagtctcctc ttttggttct acagtttctt cagccttggt atctggagtt gactcttctt
    43801 gtttcggtgt ttcctctaca gccttctctt cttcaggagc ttctggttga ttttctggct
    43861 cgactggtgc ctgttcgtct tttcttggcg cgactggttc acctgcttgt tcaacttttg
    43921 attcctcagc tggtttgtct gatggttgac tttctggctt aactgctact ttttcctctg
    43981 gttttgactc aacttctcca cctacttctt caactggagc tggttctgct gaatcttctt
    44041 tcccctcttc tactttagga agggtgtcgt cagtaggttt tacctccgat tttggttctt
    44101 cctttggact ttcttctgtt ttaggtgctt cttcttttgg agcttcctct gtctctacta
    44161 cttggttttc tgtcctagct tgctcctgat ttgttgttga ttgaggagtc tcaacttcga
    44221 ctacagtcac ctctccaggt tttgctgagg tttcttctaa aacagtgtcc aagccaagcg
    44281 ttttgaggat gtcacctgat agataaccaa catagcgata gccctccatt tcaacaacac
    44341 cctctcgact agccagtgct agggtcgcaa ctgggtctac agcccctgca ctaggaagaa
    44401 ctaccaatcc catagttcca actagaaaga cgctagcaat tttctttctc ttgtagatta
    44461 aaagcaagct cccaacagtc agcaaaccaa aagctgtcaa aacagatgct tctgtccctg
    44521 tttgaggcaa ctgatctttt tgatacacca aaccatatac aacttcattc ctgtcaggct
    44581 ttcctgtctg aattaaatct ttagcttctt gtgaaataat ctctttattt acatagtgat
    44641 aggtggctgc gtccactaca gaaggagcca tcaaaaggct tccaagaaat acagagccta
    44701 caactccctt aatcttacga attgaaaaac ggtctttttt aaacactttt atctccttta
    44761 ttcattctca aaacttccta atagcatctt gcggatagtg cgcacgcgca cctccgatta
    44821 attttggacg actagtcagt gccgttacat gggcatgacc aatctctctc aaaatagggc
    44881 gaatcggaac ctgaacatgc ttgacatgca tgccaattgc agtgtctccg atatccaatc
    44941 cagcatgagc cttgataaat tcaacctcaa ctggatcctg cataaactta aaggctgcca
    45001 actgccccga acctcctgca tgaagagtag gatggacact gacaatttcc agaccaaact
    45061 gctctgccac ctgacgttca acaacgagag cccgattgac atgctcacaa ccttgaactg
    45121 ctaaatggat acctctacta cctagaatac ccaagatagt ctccactatc agctcaccaa
    45181 tctcttgact ggattctttc ccaatctgac cacctagcac ctcactagaa gatagaccta
    45241 aaacaaaaag ggccccctgt ttcaaattgg tcttttctaa aacatcttcc actacctgac
    45301 gtgtttctct ttgaatctgt gtctcgttca tctctgttac ctctgttgtc actcttctat
    45361 cataccgttt tttcttgttt ttagcaagat agacaaccta gaaagtttgc ccaattacgc
    45421 ataaaactcc cagaattgac tgggagttag ctagtttcta ttctatttat atatatttca
    45481 actttcgttc ctttttgggg tctagaatca atcttcatct ggtaattggc tccaaaatga
    45541 agtttgagcc gttgatcgac attttgaaga ccaactcccc cacgtttgag ttgactttga
    45601 ctactatcac cagcatcttg gaagccaacg ccatcatcct caatacggat gaccaatccc
    45661 gaatcctgtt tctggacaga aagtttaata tggccctgac cttccttttc cttaatgcca
    45721 tggtaaagag cattttctac aaggggttgt aggaccagct tgggtaagac taaattatca
    45781 aaggcaacat tttcattaat ttcgtattcc agcttatctc catagcgttg tttctggata
    45841 aagagatact ggcggacatg attgatttcg tcagagagac aaatcaagtc cttgccttga
    45901 ttgagcgcca agcggaaata ggttgccaag gacttggtca cctgcaccac tcgctgacta
    45961 tcatgaaatt cagccatcca gatgatggtg tccaaagtgt tatagaggaa atgtggatta
    46021 atctggctcg aaagggcttg aagttggtac tgacgggtcg tttcttcctg gctacgaata
    46081 gctaccatca actgatcaat ctgatccaac atggcattaa attggcgagt tacttctctc
    46141 agttcatagg caccaacttc cttggcacga agattttgag caccagaagc aatttccaac
    46201 atggtttctc tcaaatcctt caaaggagca atccagcgtt taagactgaa ccacactaag
    46261 cagagacaga caagaagaga tgtgacactg gccccaagca aggtccacaa gagctgactc
    46321 cgaacctggt ctaacttttc caatgatgac acgccaagta ccgtccaatc agttcctgca
    46381 atcttctctt gactgacgta ggatttgtga ccaggagtat aaccctgacc tgtctcgatg
    46441 tagggtttca tagcctccat tttgctagac gaactataaa ctgtgtgttg aggatggtag
    46501 acaaattcat ggttttcatt gataatgaag gcaaagccct gctgccccaa ctggagttga
    46561 ttgagatagg cttccagagt ttcataagaa atatccaaac gaagcacacc aagattggct
    46621 ccctttgcat caacaagttc ttgagtgaca gaaatgaccc actgactatc tgatttacga
    46681 gctggagtca aaacaggcat agctccctga tgaatagcct tttggtacca atcctcagcc
    46741 atcatatcag aggaagtttt catctgcaca ctgtcatctg tagaaatgac ctgaccagat
    46801 ttggtcacca gcacaacagt tttcaagtcc ttatctgact tcaagatggt caaaaacaaa
    46861 tctcggattc cctcgacctt gtcttgactg ggattctcag cataggccag aacatccgtc
    46921 tgctgggtca aaccagtcga ggtggtttct agttttttga tataagactg aataaagtgg
    46981 ctagtctggc tgatggtcgt ttggctgttg ccctcaatgg tggcctcaat ggctgaagaa
    47041 cttgattgat agtagaaagt tccaaccaga gctaggagaa tgagaaagac cagaaagatg
    47101 gaaataacca ttctaactaa aagagaagaa cgcttcatcg gtcttctccc ttcttaaact
    47161 gacgaggtgt cacacctgca atctgcttaa aacgttgggt aaaatagttc atatcttcaa
    47221 aaccaacctt ctctgcgatc tcataaatct tcagatctgt agttaaaagc aagagcttgg
    47281 cttgtttaac acgttctctc accagataat cctgaaaagg caagcccaac tctttcttaa
    47341 tcaaggaact cagataggtc ggactaaaac ctaagtcact ggctaaagac tttaaactaa
    47401 attggctatc agccagatga gactggattt tctgggccat gtttccttca aacctattag
    47461 tcaataaatc ttgtaactgc tcttctttct cttccttgtc tagtttttgt ttgattttcc
    47521 ccaacatttc ctcaatatcc tgacgagaaa agggtttgag caggtagtcg tccacaccta
    47581 gtttgacagc agacaaggca taatcaaaat catcgtaacc tgttaaaaag accaaatgaa
    47641 cctgaggata ggtttctcgt accagactgg ccaactggat gccatttaga tgaggcatgt
    47701 tgatatcggt taaaatgata tctggcacct gcttttggat caattcccaa gcctgccttc
    47761 cattttcagc ctgaccgatg atttccatat cgtaggctgc tacattgacc agtttagtca
    47821 aaccttgtct taccagatat tcatcttcta cgattaagat tgtgtaggtc atgctctgct
    47881 cctttaccac ttactagtat cagtatagca aaattctcct ctaactgctt aggaaagacc
    47941 tcttatactc aataaaaatc aaaaagtaaa ctaggaagat agccacaggt ttctcaaagt
    48001 atagctttga ggttgtaaat aaaactgacg aagtcagctc aaagtatagc tttgaggttg
    48061 tagataaaac tgacgaagtc agtaacccta catacggtaa ggcgacgctg acgtggtttg
    48121 aagagatttt cgaagagtat taatcaacat aatctagtaa ataagcgtag cctttttctt
    48181 ccatttggtc tttgggaata aagcggatag agaggctatt gatacagtaa cgtaagccgc
    48241 ccttgtcctg tggaccatcc gtaaagacat gcccaaggtg agaatctcct actcggctcc
    48301 gcacttccat acgcgtcata ttgtaggact tatcttcctt gtaggtgaca acatctggac
    48361 tgatgggttg ggtaaaacta ggccagccac aaccagactc aaatttgtct tttgatgaaa
    48421 agagaggttc cccagttgct atatccacat agataccgga ttcaaattta tcccagtaac
    48481 ggtttgagaa agctcgttct gtttgatttt cctgggtaac tgcatactcc tcaggtgaca
    48541 gggtcttttt caattcctca tcacttggtt ttggatattt gctggcatca atgacaggat
    48601 aggccgcctg attaacattg atatggcagt agccatttgg atttttcttg agatagtctt
    48661 gatggtaatc ctcagccacc acaaaattct tcaagttttc cttttcaact gctagaggtt
    48721 gatcgtattt cttagccacc tcatcaaaga cttggttaat cacttccaaa tccttgtcat
    48781 ctgtgtaata aacaccagta cggtactggg tccccacatc atttccttgt ttatttttgc
    48841 tggttggatt gataatgcgg aaatagtgaa gcaggatttc cttgagagaa atttgcttgg
    48901 catcataggt gacatggacg gtttctgcat gacctgtttg gttaatcaat tcgtacttgg
    48961 ttgtttctcc tctaccattt gcatagcctg aaacggcatc cgtcaccccg ggaacacgtg
    49021 agaaatattc ctccactccc cagaaacaac ctccagctag ataaatttcg tgcaagtctg
    49081 cgtctttact aatttctgtt tttttcactg cttttcctcc ttggctaact gccgcctttt
    49141 caatttgcga ggcatctgtc tgccctgcat ttcgtatcaa tagaacatag aaaccggtta
    49201 tggctagaaa aaatactcct agcaacaaga agatttttaa cttatcattc ataagacgcc
    49261 tcctaggcta attccttcaa agtttgcaaa attgcatctt tttccatgaa tcctggatgt
    49321 gttttgacca gcttgccttc tttgtctata aaggcttggg ttgggtaaga acggacacca
    49381 taagtttcca aaagtttgcc tgatgggtca actaggactg ggagattttt ataatccaat
    49441 cccttatacc aattcttaaa gtccgcttca gattgctctc ccttatgtcc tggtgacact
    49501 actgtcaaga ccacatagtc atcaccagct tctttagcaa tctcatccgt atctggaaga
    49561 ctagccagac agatggaaca ccaagaagcc cagaatttga gatagacttt cttgcccttg
    49621 taatcagata aacggtaggt cttgccatct actcccatca attcaaaatc agccacctct
    49681 ttccctttag ctgcgcttgt tttactagct gtctgctccg tcttcatttc atctttcgtt
    49741 tggtgttcac tagtcacgga cttgcctgaa caagccgtca aacaaaggag cgaacctgct
    49801 ccaagaacac atgtttgcca ttttttcata ttgatattcc tttccatttt attcaaataa
    49861 ttgacttaaa attgaagcat ttccaaacag aaccaagaat cccatcacaa taatgagaaa
    49921 accacccact tttttgagga ttccgagata gggatgaagt tttcggaaat gtttcaaaac
    49981 ataactagag gtcagagcta gaagcaagaa tggtagcgcc aagcccagcg tatacaccaa
    50041 catgagacca gctccctgcc aagctcctga accacctgaa gccgccaagg ccaaaacaga
    50101 ccccagaacc ggccccacgc aaggcgtcca agcaaaacta aaggtcaagc ccaataaaaa
    50161 tgcctgacta tagcccttac cattttgccc ctgtccttgc agttgtagcc tcttttcctt
    50221 ataaagcccc ttaaagtgta gaatctccat ttggtgcaaa ccaagaagga taataattgc
    50281 cccagtaaga tattggaacc aagaagcata aagcaaatcg cctaaaaaac cagctccata
    50341 gcccaacaaa ataaatataa aggaaattcc tgctataaag gccagagttc gtaataaact
    50401 agtaactgag attgaaaatt tgccgctaga agcctgagca ccatccttat catctagtaa
    50461 cactcctgta tagaccggta acaaaggtaa gatacaagga gaaaagaagg atagaatccc
    50521 tgccaaaaag acacttagaa aaaagaaaat atgacccata aagttcctcc tatcatttta
    50581 ttgatagatt tattatactc cttccatttt cgaaaaaaca gggacaatga taggggaaaa
    50641 taggaattta atcagatgat ttagaaatct tggacaaaaa ctatacaaaa aactgtcaaa
    50701 gcacaaaagc gcatagtatc aagattctat aaagccttga tactatgcgc ttttgtaatg
    50761 gataaatagt tagtcttttt taaagacctg atctttcaaa ctctgcatac tggcattgat
    50821 caccgcgcct aggataacaa ttttagcaat caagataaac caaaacatca taacaacaag
    50881 aagaacggaa cctaaaattc ggacatccac caaatgatgg acatagtaat tgagataact
    50941 agagaacaga gttagtacac ctaaaatcac caagagaaca aaggcactgc ctggtagggt
    51001 atagctaatt ttcctgttag atagattggg aagaaaataa taaagcatga ccaagatagc
    51061 aaagaggagg gcgtaaatca gaggacctgc caacccttgt aaagcctgat agataatgcc
    51121 atcttttgtc caataatgag caagtaaagc caaaatcatc tgaccaaata agatcaaaaa
    51181 caaggcaaac gcaaagagga actgcaagcc aaaactgact aggagactta gcatctgatg
    51241 ggaaataagt ccacgactct tttcgacgcc ataagccttg ttaaaagctt tttgcaagaa
    51301 atttatagat tttgaaaaac tccataacgc cgataaaaca gaaaaactca ataaacctgt
    51361 tgaaggttgc gtcaagactt ctctggctat tttttccaca ccttcataga ggcttggggg
    51421 caggacgtct ttcataaagc ccagaaattc tcccacagga atctgaaaat aggggaggat
    51481 attgaccacc accaaaagca gggggaaaat cgaaatcaac caatagtagg ctactgcgac
    51541 actggtcaac tcactatctg atgcttgata ataatgcaaa aaagctttta ataaaggctt
    51601 gtctatcagc tctttccacc actttttcat gtcatactcc ttcatttata atcttatact
    51661 caatgaaaat caaagagcaa actaggaagc tagccgcagg ttgctcaaag ccctgctttg
    51721 aggttgtaga tgaaactgac gaagtcagtc acatatataa tccaaggcga cgctgacgtg
    51781 gtttgaagag attttcgaag agtattaact aatttcttct taccaattcc accatatcat
    51841 acggcagggt attggcagct tccttcaagg aatagttctc taagttattt acattttgtc
    51901 gtaatttctt ggcatactta gtcgtaatca atcgtttttc ttcgtattcg aaaatcaact
    51961 tgcgctccag ataatagcct ctcagcattt catcgatatt gttgggtttg acacgattga
    52021 taacccgttc gacaaaggca ccactgctga taatagctgt ttctcgaaga cgagactcct
    52081 gcataaaact aatcaaagag cgtctgtaga ctcccttcag gttttccaaa ctttcaataa
    52141 tcatctctgt attggcaaga tagagctctg caatttggtc ataatcaaga gcacggagac
    52201 ggctttgctc cttgtccttc cagctacgga aggtctttcc aagagtaaaa acttcatgaa
    52261 gaagaaaacg taaaatcctc aaggaaacaa gaaaataata ggtcagtctt gaggcaagtt
    52321 tacgattgat tccttgttct atatttttca gataacgttg gtaaactcgg taagcacgat
    52381 tgctaatgtt cccctcttca taggcctgtt ccaaaccatc actttcaata ctaagaatta
    52441 agagtttcaa agcagcccag tcttcttgat catcctggtt ttcttggctt aaaatgagat
    52501 tttcaatacg tccatgataa ttgtcaatag ccgcatagag gggaagttta tttctggtgt
    52561 cttccaactc tttttccaac tctagcgtta cttcattcaa aatggcgata tgcatgagat
    52621 aatccttgct ttcttcctct tcatcagaaa gatgaggcaa gaccaagaga cctgttaaaa
    52681 agctgacaag cgtcacacct gcaacaagga aaagcaagag aggatactcc tgttctagat
    52741 tacttggtat caagagaatc gtagcaatcg acaccgttcc cttaacacct gaaaaggtca
    52801 agagaaacat gtccttcata tacttattta gctttttctt taggcgtcgg gttctatagg
    52861 cataatagcc atagatcata ataaaacgaa tgacaaagag gacaaaggta agggcgatga
    52921 gagatagcaa taaaagtaga ggattataga ttggattggt caagataggt tctgctatca
    52981 tttccaactc catccctaaa atcacaaaga cagaaccgtt gagcataaag gtcactgtat
    53041 gccagaccgt ctcggtcacc gtatccactt gggcttcgag gagcgtgatt ttcttgaagc
    53101 gacttgcctt taaaattcca gcaactacga cggcaataat ccctgaaaca tggacttctt
    53161 ctgccagaaa gaaggtcact agaggcaaac tcaattctaa taaaagttca ctggcaatat
    53221 ccgttgcgcg cacacttagc aagaaggtat ggaggaagcg gttggtcatg gctgttaaaa
    53281 atccaattaa aaaaccgcct aggattgaaa agatgagcga actgctagct tgccccagag
    53341 aaaaagctcc agttgtccaa gctgtcaaag ctacctgaaa agccaccaaa ccagaagcat
    53401 cattcaagag tccttcgccc ttaagaatat tggacacgcg cttaggaaag ctaaaacgct
    53461 ccgaaagaga ggcaaaggcc accaagtccg taggaccaag ggctgcccca acagccaagc
    53521 aagctgccaa gggaaggctg aaccaaagaa gatgggccaa gccacccaaa ctcagggtcg
    53581 agataaaaat cactggaaat atgagataaa caatgattcg ccagtgtttt aaaatagccg
    53641 taacatctgc ttcttcagcc tctcggaaaa gcaagggtcc gataaccagg gccaaaaaca
    53701 actccgtatt gaggtgaaag tcggtattgg gtaaaaagag accaatcaca attcccaaaa
    53761 gaatttgcac caaagggaga ggcaaaaagg gcaggagctt attggttgta cttgagacaa
    53821 tcaaaaccag taaaaatagg atgaggtaaa tcagtaattc cacgcacgtc ctccttaatc
    53881 ttttttacaa caggattcaa atatctcctt ctgctctttg attttttggt caatcttgga
    53941 acagtctttg tgctcaattt ttctctggca ccgttccatt tcaagagcaa ctaatttttt
    54001 cttgatttta agcatttttt tgctcatatg cgcttggtct agcacgccca ccgatcgttc
    54061 gtggtgggtt gattcaacaa aattctggcg catggcatcc agcttttcgt gtaggtattg
    54121 tttatccatg tctgtatctc tctaattttt caatcatcac taaaaacggc gggttgttga
    54181 cttggtttaa agttcggtaa atggcagctg tgtactcttg ttggttcaac tggattacaa
    54241 aatccaagac agcatctctc tcgaggtcgc ctccttcatg accatagtaa atcataatag
    54301 caattcgtcc acccttgaca agtaagccac atagcttttc taatgcctca atcgttgtct
    54361 gcggtcgggt gatgacagac ttatcagctg acggcaaata gcccaaatta aaaatccctg
    54421 ccttagcttt tgtcacaaac tggtccagtg tctcatggcc ttgcaagatt aactgggcat
    54481 ttgtcaagcc agcctgatgc aaacgctctt gggtcttttc caaggcttgc ttctgaatat
    54541 caaaggcata gacttgcttg gctagcttgg ctaaaaaaag cgtgtcatga ccatttccca
    54601 tagtcgcatc cactacgaca tcctcttttg tcacgacctc agccaaaaaa tcatgtgcca
    54661 tctcaagtgg tcttttcatt ttcaaactcc tgttttacag ccttgcatcc ttgaacactt
    54721 ccacgacgtc gcatctccat ctcaatgctg ttgagagctt cccatttatt gaggctccac
    54781 ataagcccaa tcagcatatc cctaggtgca tctcctgtga ttcgatggat gacgatatgt
    54841 ttgggaatga tttccagttg gtcacagatg accctgacat attcgtcctg actcatcaat
    54901 tgtaaacgtc cctcatggta atctcgttgc atacgagtat ttgtcataag atggagcaaa
    54961 tgcagtttaa tcccttgaat atcgttattc gtgacacaac ggcggacatt ttcaaccatc
    55021 atctcatggg tttcaccagg caaaccatta atcaaatggg aaacaatctc aatcttggga
    55081 tactttctca aacgcttgac cgtttccacc tacaattcat aagaatacgc acggttaatc
    55141 aggtcagaag ttgcttcata agtagtctac aagcccaatt caaccgtcac atgcatgcac
    55201 tccgataact cagccaaata ttcgatggtt tcgtctggta aacagtctgg gcgcattcca
    55261 atattgattc ctaccacacc tggctcattg atagcctgtt cataacgctc tcgaataact
    55321 tccacctttt catgggtgtt ggtaaaattt tgaaaataaa ccagatactt ctgaacatcc
    55381 ggccacttac ggtgcataaa gtcaatttcc ttataaaatt gctcacggat aggcgcatct
    55441 ggggctacaa tagtatctcc agaacctgaa accgtacaaa aagtacagcc tccatgagcc
    55501 acagttccat cacgattggg acagtcaaat tccgcatcaa tagggacttt aaaagtcttt
    55561 tctccaaaga gttttcgata ataatcattc aaggtattat aagattttat aactttcatt
    55621 ataacaaaaa tcacccacaa tctcaaaagc ctgactttcc tataaattcc tctgtttctc
    55681 gtttccatta gctttttttt atgatacaat atgggtatga ttttaatgaa attagcatct
    55741 attttattat tgatactgac cttagtcgtc tgcattatcc taaccaaact ttttagatta
    55801 aaaaaactag gacgaaactt tgcggatttg gcttttccgg tcttggtatt tgaatattac
    55861 ctgattacag ctaaaacctt tacccataat ttcctcccta gactggggct agccctctca
    55921 atcctagcca ttattctcgt ctttttcttc cttttgaaaa aactcagctt ttactatcct
    55981 aaattcatca aattcttctg gcgtgcagga ttcttattaa cccttatcat gtatatagaa
    56041 atgattgttg aattgttctt aatgaaatag tcgaatccct aagcattttc tagggatttt
    56101 tgctttctct acaaaatagt atagacaata acactataca attttataca aagaaaagag
    56161 tctgggacaa tagtctctta tctccaaaaa aagcaacgga tttgccgttg ctttttttgc
    56221 atggttacga tagtcttggt aaaatagaat tgcccaataa accatttaga aaggctatcc
    56281 catgcatatt cactataaca caaatcaaac aactttacca ctagaaatca gttccttctt
    56341 accacaagac catctcgtct ttactattga aaaagtggtg aataccttgg aggaacatca
    56401 cttctacgcc ttctatcatg cctttgatcg cccgtcttat caccttaaaa tgcttgtatc
    56461 tactcttcta tttgcctatt cacaagggat tttctctggt cgaaaaattg aaaaatggaa
    56521 gagttagtga ccttagattg tttgtttatt gacggaacta agattgaagc caatgccaac
    56581 aagtatagtt ttgtgtggaa gaaaacgaca gagaaattct ccgccaaact tcaagaacag
    56641 atacaggtct attttcaaga agaaatcctc cccttctgat taaatatgcc atgtttgata
    56701 agaaacaaaa gagaggacat aaacagtcag ctaaaaactt agcgaattgg cactataatg
    56761 acaaggagga tagctacaca catcctgatg gctggtatta tcgttttcac cataccaaac
    56821 atcagaaaac acagacagac tttcaacagg aaatcaaggt ttactacgct gatgaacctg
    56881 aatcagtccc tcaaaaggga ctgtatatga acgaacgcta tcaaaacttg aaagctaaag
    56941 aatgtcaggc gcttttatct cctgaaggta gacagatttc gctcaacgca agattgatgt
    57001 gaaacctgtc tttgggcaga taaaggcttg tttgggttac aagagatgta atctgagagg
    57061 gaagcgtcaa gtgagaattg acatgggatt ggtacttatg gccaataacc tcctaaaaca
    57121 tagtgaaatg aaataagacc aggacaaatc gataaggaca gtcaaattga tttctaacaa
    57181 tgttttagaa gtagaagtgt actattctag tttcaatcta ctatacaata agagaacgac
    57241 tcaaaattaa aaagctagag ttccgcaatt ggaaatatct agcttttttg tggttgagaa
    57301 ctattttgtt ccagactctt tatcttctat ttaggacaag agtttttctt tggtctttaa
    57361 tgataaagaa ggtatcaaaa tttctagtct tcttttttac ctttagtaac tactaatcct
    57421 gcactcaaac ctagaagagc taaacctgct gctactgctg cttggcttgc cgcactacct
    57481 gtatttggta actgggcttt attagtttga tcagcttcac ttgaatcaat tggttttgta
    57541 tctgcttttt ctgacacttg tggtttttta gcttcttgag ctactggttt ggttccaacc
    57601 aagacgatgc ggtctgtcgg aacttctacc acttcacgga gtttttcttc cttacttcca
    57661 tcaggattaa tcactgtaaa gatacgttct tttccaactt ttccttcttg ttctacacga
    57721 gtttcaccta gatacagtgt tgaatctttt ttctcaactg tcttgtaggc caaatctttt
    57781 tcaacaaatt cgagttttgg aagatcttct tgtacagcag aaactggttt ttccttagtc
    57841 aactggatac ggtattcctt gacttgtttt ccactttctg aaacgaggcg aacaagtact
    57901 ggaaggctat cttctccact atctaccaca gttgaagcta cttgattgtt ttcttcaact
    57961 gagacttttg gccgttgacc tttataggta atttgatagt cttgacgatt ttcagcgaaa
    58021 tcagcaagtt cttttccatc tacaagaatc tttgattgcg tgctttcttg aggcaattca
    58081 cttggtgcaa ggaaggtcat ctcaatcatc gcaacaccgc tcttgtcagc tttacgctcc
    58141 atacgccatc tcatggcttt ggctttgaca gctttaaatg ttacgttgat ttcatcacca
    58201 gctgcgatgt ctttatccgc acgataaggc acagcttccc aattttctgg attgttaaat
    58261 ggatgtccag attcgtaggc ttggtagttt gaatagtagg taggtacttc aaagcctggg
    58321 ccgacatagc gttctaaaac gagtttagat ggtgcatccg taccactatc tgcaaagaag
    58381 tgaagtttgg cttgagcaac agtccgttct acaatcttac cattttcacg gaagatcaca
    58441 cccgctgata cttctggatt agaagatggt gttggtgacc agtttgtcca acgacgattt
    58501 tctgaatgat ctccgtcatt gagatagtca acgcggtcat gagagttttt gtcaatatca
    58561 ttggttgctg aagcaaaggc ctggttactg ttttcatcat agttagggtt atctgaaaga
    58621 gtctcaccaa gtttgtctgt cactcgtaca gtgacctcag caacaaggtt actaccaagg
    58681 acacggcctc gaacagtaaa ttgacctgct tttgtcagat tttccgctgg aacttcttcc
    58741 cattcaactg tcaggtcttt tgtttcgtag ccgtctttac ctgtgaagta aactggaacc
    58801 ttagtcggca attcaagtgc ttgacctact tgtagcaagc gagcttgttt aaccgcagca
    58861 actggtttat gagaaagtaa gttcttatcc ttagtgaagt gcagacggta ttctcctaag
    58921 atgtcgccat tttcagcttt cgcgatgaca cgaactggct caccttcacg aacgcttgga
    58981 acgacggtag cgagaccatt gttgctaaca tttgctgtga ctgccggaac ttttccatct
    59041 acagactcaa ggtagtagtc tgtcaaatca gggttgaagt ttgctaagtc tttgccgtca
    59101 acttggattc ttgtttgtcc ttgtttggct gccgcaactt gtttcgcaaa gatttgtacc
    59161 tctgtgatag acgttccacg cttgttatct gctttaacca tgcgaatacg aatagcatag
    59221 gtttcaactt tatcaaagct aaagtggttc atttctccag ccttgagttg agcaggggct
    59281 tttagattag taactggttt ccagttggca gaatcattaa agacatggtc ctcattacca
    59341 acaaaactag ggtttttagg agctgttggg acagtcttac caacataata ctcaatcaca
    59401 taagacttcg gtgcaccaac tccatggtct tcgtggaatc cgacacttag attatcaacg
    59461 gagcgtttgc tcaagatacc tgaatctcca aacagaacac cgactgaagc ttctggatta
    59521 ctacgattcc agtttgtcca acgattggct ggttggttat tgtaggaaat gagcttgtca
    59581 ttaacatttg aaactgggtc gcttggattt gaatctgaag caaaggcaag tggcaattct
    59641 gaaccggtcc attggtcaga aatgtttgca ccttgctcag tttgagcaga tacgcgaaca
    59701 tgaagtttag ttgttaattg agtaccttct aagcgaccat taactgtaaa gacaccttcc
    59761 ttagcgtatt gctctggacg aatcgcatcc catgcaacct tagctgatga aacgtgacca
    59821 tttgaatcat atgtccgaac actttctggt aattgtggtg cttctgcgat tggagttgtc
    59881 acactgactt cttcaactga aacgatacct tctacagaga cttttgcacg cgcttcaagg
    59941 tcaattcctt caactttacc tagtacttca aatgtttgat aggagtctag tttttctttc
    60001 ggaatagctt gccaagtgac tttatgagtt ttagggaaac ctttgtcata ctcaactgtt
    60061 actgttgctg gaagacttgg ttcctgatgc aaatctgtca ctacatttac aggacggatg
    60121 gattgcgcaa tcttcttctc agtattggct tggatagtga gttcaacttg gcctttagct
    60181 ccctcatatt cagcgttcag agtgactgct cctggcttat gcaactcaag cattccttta
    60241 cgaattgcga cttccccttc accacttgta gagaaggtta ctttatcagc tggtaataca
    60301 gcttgcgttc catcttgata gtgagctcga accgacaatt tgacagtttg gtcttctttg
    60361 agactgtcag ctttttccac ttgcaagctc aagtgagcaa tttttggcgc ttcttcaagg
    60421 aattgaattg cataggtttg aagagggcca ccatctttag gctgaataaa gatgctcgca
    60481 cgcatgccgt ttgctgcgct tgcttgaaga actgtaacag ctgcattttt agcacttgct
    60541 gtgacttctg gcaacttagc tccataagca agagtgcggt attgcattgg tttttgacta
    60601 gtaagacctg tgacagcttc accaccaacc gttacagttg gtactgcagg tgccgcagga
    60661 ttgccttctt ctaccacaag ggttgcatga attggttgac cttctaaata accggtcgct
    60721 tgaatacgag aacctggaat tgctaactta gctttatctt cttcggcaat ctcccacttg
    60781 tccacttcat actcttcaac acttccatca gtcaaaacat aggaaacaga tttgtctaca
    60841 gaattcaagt cagtatttgg agcaatacgt ttcacaactg gtagctctga tttaagagca
    60901 atcacttcta cacgagcttc tacttctcgt ccgtcagcca tacctttcac cgttacaata
    60961 ccaggcttgc tcacatctac tgaagaccag gttacaggac gttctgcacg gctaccatca
    61021 ctgtatacaa acggaacagt ggtaggcatt tcaggtgcct ctccaataat ggtctgtact
    61081 tttggcactt ctgtccccaa aacagtcttc tcttgtcctt cttttttacc agtaaagaca
    61141 gtgacttgac tagatttcaa gagatctgaa tgggctgtca gtgtgaattt ccctgcttgt
    61201 tcagttgatt tgacaatggc aacaccttta ccattaaatg ctttacgaat ccaagaacca
    61261 tctgcttgcg ccttatagcg ttcacggctg gcttgttctc cgttatctac accgaccagt
    61321 tgaccttggc catgcaattg gaagcgaacc agattattag cagttggaac cacattcccc
    61381 tggctgtcaa caatttcata gtagatgtaa gtcaagtctt ttccatctgc tgcaatcgca
    61441 tggtcttcct taataagacg aactgccgct ggcttaccag cagtcgtaat cttatctcga
    61501 gcaatttcct tgccagattc atcacgagca attgcttcca aggtacctgg ttgataggca
    61561 actttccatt caagataaag ttcattagca tttgcacctt cttggtaagt ccgcccatcg
    61621 ctggtttgtt ttttattgaa agtcttaaga ccaagagatt ttccattcaa gaacaattct
    61681 acactagaag cattcgaata agcacgaact ggaatcttac cttctgagtc agctactttg
    61741 gatgctaatt ctttgttttc ccagttccag tgaggaagaa ggtgtaccat cggtttcttc
    61801 ttaacagaaa cccattggct ttggtagagg tagaagtcat gttttggaat gccggctgta
    61861 tctacgatac caaagtaaga gctcttaaca ggagtttgat tttggttgtg ccatggtgta
    61921 ggttcaccaa tatagtccgt acctgtccag ataaactgtc cagcatagcc agcgttgtca
    61981 cggtcaaaag tccatgaagc ggttgctgtt ttcccccaac caacacgatc attcccatag
    62041 tcagactgtt cataattacg ctcaggtcca ttgctatgtt tcaattcacg ttcagggcga
    62101 tagtaacttc cacgtgtacg ggtagctgaa gatgtttctg atccataaat caaccatttt
    62161 ggatgcttag ctctaagggc tttgtaatta tcttcagaat agttaaatcc aacagcatcg
    62221 agttcatcag caattttctc atgccctccg ctaccattac cgaaacggaa tttatctgct
    62281 cccatggtaa catagcgagt cttatcaaca tccttgataa ccttgaccaa acgtttaaca
    62341 gttgctaaag agtgggcatc accattagct tcacctattt cattaccaat tgaccacatg
    62401 aagatagcag ggttattttt gcctctttcg accatggtac gtaggtcaaa atcagaccat
    62461 ttttcacctt ttcgagcttc tgggtgagtg gcatcttttt caaagaaacg tccatagtca
    62521 taaggtttct tgccaccata ccaagtatca aaggcctctt cctgaacgag taaacctagt
    62581 tctgctgcga tttgcaaggt ttgctcacta gcagggttgt gggttgtacg gatggagtta
    62641 actcccatct ccttcatttg tttgagacgg cgatattctg ctttatagtt ttcttctgct
    62701 ccaagcgccc catggtcgtg gtgcaaggat actccatgga atttaatacg ttcaccattc
    62761 aaagagaaac cttcatttgg agtccagtga tagtaacggt aaccaaacaa atccttctta
    62821 gcatcaacca attgaccgtc acggtaaaca cgcgtaatca attcgtacaa ggcaggtttg
    62881 tcatttaaaa cggtccagag ttttggtctt tcaacttcta aaatcgcatc taggcttgtt
    62941 gattcatgtg cttttaaggt acgactcgct gtacgaacta agcctgttac agcatgacca
    63001 cctcgttcaa cgatttgata ttcggctaca agttcatggt ctttgtcgtc cgtattgacg
    63061 attttgctgg tcacatgagt ttcaaccttg ccatgttgtt gttcttcaag ttttggtgtt
    63121 aaaatagttg tcccattttt ctcaacatgc accttatctg tcacttgtaa agtcacatca
    63181 cgatagatac cacttcctga ataccaacgg ctacttggct gtttgttgac tgcatggaca
    63241 gcaatcacat tctcacgacc atctttatga aggtatttgg tgatatcgta tgagaactgg
    63301 ttataaccat ttggataatg ccccactaac tgaccattga cataaacttg agaatccatg
    63361 tagacgccat caaaagtaag gcgaacattt ttcttgaggt ctttttcatc tagtttgaaa
    63421 gtcttgcgat accaagcttc cccaccgttg agctgtccac cttcattttg tgcaggagat
    63481 tcatgatcga aatcgttaaa gatactccag tcatacggta aatctaattt tttccacgta
    63541 gatacgtctg catcaggttt aatggcttcc ttagaatttg cattgagttt aaagtaccaa
    63601 ttttgattaa aatccacttt cctgtcttca atcatttgat tcacttcttc atttgttaca
    63661 gctttagcat cttccttgag cggtttttct tgacttgaag cttgtgattc tatccttgga
    63721 gctttttctt ccggtttagc agacactttt tcctcttttg gagttacggc ttcatcttct
    63781 ttcttctcag atgcaatagc ctcagttgaa ctaggttcac tttgttctgt cctttcaact
    63841 acatttttag tttccaaagc tttatcagcc ttttcttcta ctatcatttt ttcctcttta
    63901 ggtttctcag cagtatgagt aataagtgtt tcatccgcat aaactacaga ttctccagct
    63961 atatttcctc ctaatagaac tgcacaagtc ccaatcatta ctgagcaagc tcccacagca
    64021 aacttacgaa tgctataaac tcttttccga ttccaatggc ctttccccat aaaaccctcc
    64081 ttatattata tttagtgcag ttagctacta ccaaagccca agtggtatac atggtatgac
    64141 aacctagttt caacaattta cactctgcga aaatccaatt caaacttcgt cagtgtcgcc
    64201 ttgccgtaga tatgatt
//
LOCUS       DAVHLA010000008        46589 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVHLA010000008 DAVHLA010000000
VERSION     DAVHLA010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46589
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.008"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(612..1025)
                     /gene="ndk"
                     /locus_tag="VVO77_000591"
     CDS             complement(612..1025)
                     /gene="ndk"
                     /locus_tag="VVO77_000591"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEU5692644.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(1136..4813)
                     /gene="rpoC"
                     /locus_tag="VVO77_000592"
     CDS             complement(1136..4813)
                     /gene="rpoC"
                     /locus_tag="VVO77_000592"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEU5692645.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(4846..8457)
                     /gene="rpoB"
                     /locus_tag="VVO77_000593"
     CDS             complement(4846..8457)
                     /gene="rpoB"
                     /locus_tag="VVO77_000593"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEU5692646.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVIAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            8873..8943
                     /locus_tag="VVO77_000594"
     tRNA            8873..8943
                     /locus_tag="VVO77_000594"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:8905..8907,aa:Cys,seq:gca)
     gene            complement(9141..10472)
                     /locus_tag="VVO77_000595"
     CDS             complement(9141..10472)
                     /locus_tag="VVO77_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEU5692647.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(10763..11587)
                     /gene="endA"
                     /locus_tag="VVO77_000596"
     CDS             complement(10763..11587)
                     /gene="endA"
                     /locus_tag="VVO77_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEU5692648.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(11626..11814)
                     /locus_tag="VVO77_000597"
     CDS             complement(11626..11814)
                     /locus_tag="VVO77_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEU5692649.1"
                     /translation="MNKKSSYVINRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(11807..13090)
                     /gene="murA"
                     /locus_tag="VVO77_000598"
     CDS             complement(11807..13090)
                     /gene="murA"
                     /locus_tag="VVO77_000598"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEU5692650.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(13114..13344)
                     /locus_tag="VVO77_000599"
     CDS             complement(13114..13344)
                     /locus_tag="VVO77_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEU5692651.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTDENTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(13402..14439)
                     /locus_tag="VVO77_000600"
     CDS             complement(13402..14439)
                     /locus_tag="VVO77_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEU5692652.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     INDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(14423..14911)
                     /gene="coaD"
                     /locus_tag="VVO77_000601"
     CDS             complement(14423..14911)
                     /gene="coaD"
                     /locus_tag="VVO77_000601"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEU5692653.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPIENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            complement(14901..15440)
                     /gene="rsmD"
                     /locus_tag="VVO77_000602"
     CDS             complement(14901..15440)
                     /gene="rsmD"
                     /locus_tag="VVO77_000602"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEU5692654.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQITKEIGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYTKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(15505..16497)
                     /locus_tag="VVO77_000603"
     CDS             complement(15505..16497)
                     /locus_tag="VVO77_000603"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEU5692655.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(16608..17291)
                     /locus_tag="VVO77_000604"
     CDS             complement(16608..17291)
                     /locus_tag="VVO77_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEU5692656.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYFLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(17347..18087)
                     /locus_tag="VVO77_000605"
     CDS             complement(17347..18087)
                     /locus_tag="VVO77_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEU5692657.1"
                     /translation="MTIITSKANSVVKNTKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFTLENYRDQLATFSQTVWVSEDILLDLADSQTPQGIVAVVQREEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            18121..18399
                     /locus_tag="VVO77_000606"
     CDS             18121..18399
                     /locus_tag="VVO77_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEU5692658.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            18477..19403
                     /gene="yidC"
                     /locus_tag="VVO77_000607"
     CDS             18477..19403
                     /gene="yidC"
                     /locus_tag="VVO77_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEU5692659.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(19478..20272)
                     /gene="pflA"
                     /locus_tag="VVO77_000608"
     CDS             complement(19478..20272)
                     /gene="pflA"
                     /locus_tag="VVO77_000608"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEU5692660.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTRQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(20398..21648)
                     /locus_tag="VVO77_000609"
     CDS             complement(20398..21648)
                     /locus_tag="VVO77_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEU5692661.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(21715..22542)
                     /gene="purR"
                     /locus_tag="VVO77_000610"
     CDS             complement(21715..22542)
                     /gene="purR"
                     /locus_tag="VVO77_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEU5692662.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(22809..23750)
                     /locus_tag="VVO77_000611"
     CDS             complement(22809..23750)
                     /locus_tag="VVO77_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEU5692663.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(23740..24996)
                     /locus_tag="VVO77_000612"
     CDS             complement(23740..24996)
                     /locus_tag="VVO77_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEU5692664.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVAVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYEVGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGVLFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(24998..25660)
                     /locus_tag="VVO77_000613"
     CDS             complement(24998..25660)
                     /locus_tag="VVO77_000613"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEU5692665.1"
                     /translation="MSEYKLSENNWTRVAVFAGGDRGHYRTDFDAFVGVDRGSLWVLE
                     EDLLLALAVGDFDSVTEEERQVIQKRAQHFVQARPEKDDTDLELALLTIFEQNPQAEV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMRQIEIEDGQNLIAYCSEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(25623..26279)
                     /locus_tag="VVO77_000614"
     CDS             complement(25623..26279)
                     /locus_tag="VVO77_000614"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEU5692666.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTSVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            complement(26290..27168)
                     /gene="rsgA"
                     /locus_tag="VVO77_000615"
     CDS             complement(26290..27168)
                     /gene="rsgA"
                     /locus_tag="VVO77_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEU5692667.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(27170..28042)
                     /gene="rsmA"
                     /locus_tag="VVO77_000616"
     CDS             complement(27170..28042)
                     /gene="rsmA"
                     /locus_tag="VVO77_000616"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEU5692668.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILVDTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(28428..28574)
                     /locus_tag="VVO77_000617"
     CDS             complement(28428..28574)
                     /locus_tag="VVO77_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692669.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDKNMTNHLLLVQILVHGYLLDFA
                     SIEG"
     gene            complement(28567..29208)
                     /locus_tag="VVO77_000618"
     CDS             complement(28567..29208)
                     /locus_tag="VVO77_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5692670.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(29210..31240)
                     /locus_tag="VVO77_000619"
     CDS             complement(29210..31240)
                     /locus_tag="VVO77_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU5692671.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYATYGEGKLPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSVYYQGLFTDYL
                     QNFSSESVEVTSQKHYLPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(31317..31613)
                     /locus_tag="VVO77_000620"
     CDS             complement(31317..31613)
                     /locus_tag="VVO77_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEU5692672.1"
                     /translation="MKQTVKKLALVASIAATLGGSVAVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            complement(31933..32832)
                     /locus_tag="VVO77_000621"
     CDS             complement(31933..32832)
                     /locus_tag="VVO77_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU5692673.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            complement(32904..33464)
                     /gene="rnmV"
                     /locus_tag="VVO77_000622"
     CDS             complement(32904..33464)
                     /gene="rnmV"
                     /locus_tag="VVO77_000622"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEU5692674.1"
                     /translation="MKERISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(33464..34237)
                     /locus_tag="VVO77_000623"
     CDS             complement(33464..34237)
                     /locus_tag="VVO77_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEU5692675.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVIQMNIVGFDKPMIE
                     RALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHPKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIRLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(34542..35435)
                     /locus_tag="VVO77_000624"
     CDS             complement(34542..35435)
                     /locus_tag="VVO77_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEU5692676.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEVTPEY
                     KLETTPGGDKGGNIGSSDANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIAMVTVPKRLVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
     gene            complement(35719..35853)
                     /gene="rpmH"
                     /locus_tag="VVO77_000625"
     CDS             complement(35719..35853)
                     /gene="rpmH"
                     /locus_tag="VVO77_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEU5692677.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(35998..37212)
                     /locus_tag="VVO77_000626"
     CDS             complement(35998..37212)
                     /locus_tag="VVO77_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU5692678.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(37368..37661)
                     /locus_tag="VVO77_000627"
     CDS             complement(37368..37661)
                     /locus_tag="VVO77_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692679.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVKVIMICQLESLVPLLYPSFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            37810..38262
                     /locus_tag="VVO77_000628"
     CDS             37810..38262
                     /locus_tag="VVO77_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEU5692680.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(38297..39685)
                     /locus_tag="VVO77_000629"
     CDS             complement(38297..39685)
                     /locus_tag="VVO77_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU5692681.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELHRQL
                     KAYERHKERNKS"
     gene            39751..40713
                     /locus_tag="VVO77_000630"
     CDS             39751..40713
                     /locus_tag="VVO77_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEU5692682.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HTLDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLTMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(40710..40901)
                     /locus_tag="VVO77_000631"
     CDS             complement(40710..40901)
                     /locus_tag="VVO77_000631"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692683.1"
                     /translation="MNTIERTRRLVKGCATHCFEVVDRTDEVSSKHVFEVVDRTDEVS
                     NHTYGKATLTWFAEIFEEY"
     gene            complement(40965..41975)
                     /gene="ccpA"
                     /locus_tag="VVO77_000632"
     CDS             complement(40965..41975)
                     /gene="ccpA"
                     /locus_tag="VVO77_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEU5692684.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(42400..42999)
                     /locus_tag="VVO77_000633"
     CDS             complement(42400..42999)
                     /locus_tag="VVO77_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU5692685.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVAVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(43001..44098)
                     /locus_tag="VVO77_000634"
     CDS             complement(43001..44098)
                     /locus_tag="VVO77_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU5692686.1"
                     /translation="MLERLKSIHYMFWTSLIFMLFPILPVVIGELPAWHLLVDILFVV
                     TYLGVLITKNQRLSWLFWGLMLVYVAGNTAFVAGNYIWFFFFLSNLLIYHFGVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQ
                     VKQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMQAYPQVEKELR
                     EIQQISKESMCEVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     DSMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(44098..44835)
                     /locus_tag="VVO77_000635"
     CDS             complement(44098..44835)
                     /locus_tag="VVO77_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5692687.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GELANFMRDYLISMTAFSMMSTTILSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAVGKCLPTYQLMELLKTFLNEGDINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(44837..45721)
                     /locus_tag="VVO77_000636"
     CDS             complement(44837..45721)
                     /locus_tag="VVO77_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5692688.1"
                     /translation="MDMIKVQGLHKNIKGKAILKDISFEVAEGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLSVTSSQLDYIRGYLPQENVIVQKLKVKELVAFFQSIY
                     PNPLSNQEIDQLLQFDKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKLVFLDEPTAAMD
                     TSTRQRFWEIVQDLKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(45708..45902)
                     /locus_tag="VVO77_000637"
     CDS             complement(45708..45902)
                     /locus_tag="VVO77_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692689.1"
                     /translation="MKKAFLYLFIGLSLVVWLVEMFTGWFDQALLRQFIRGAWGLGFM
                     IFIAFPMGMEWLKGEYHGHD"
     gene            complement(45899..46090)
                     /locus_tag="VVO77_000638"
     CDS             complement(45899..46090)
                     /locus_tag="VVO77_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000791802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692690.1"
                     /translation="MKNKMIVAMSLVAAGVMTYLMFSGLDEDFYHFPWELFAGFGMMS
                     WLIREGLKLVSDVKKEFEK"
BASE COUNT        13334 a        10803 c         8835 g        13617 t
ORIGIN      
        1 tattccatgt tattttgagg aagatattgt gaaagtcaaa gatgatgata aagttgagtg
       61 gaatttgtta gaatttcaaa aatttagagc atttttgact tagtaatctg tgttgaaggc
      121 tcaaaaccta tggtaaaaaa gtaactttga aaacgtattg cctccaaaga tttagttaaa
      181 taatgattta acacaaaaag aaattattga agttctggaa agatgttgtt tcagtattga
      241 gaaaaggtgg gaaaaacttg cgattttcac agagaaagga agaaaaagta tagaaatata
      301 gtcaattgaa acaagaacag gataaaagaa ccttttgtgc catatttttc tcctttcgct
      361 ttacaattgg attgaacacc tttattgtat cgcgtttgga gtttttttgg tataaccttc
      421 gacgcgcacc cgcatagcgg gtgttttttt gtctcgcacc taacggagcg agacgaacta
      481 atagtcactt aatcaaaaaa cgcaccatat caaaaactaa aaagtttgat atcatgcgtc
      541 atgtcttaaa ctaattgact atactttcta ttcaaatgag cttttaacca attgattgag
      601 ccaatccact cttaaaacca aagagcaatt tctcgcttag ctgactcttc tgaatctgaa
      661 ccatgtacaa cattttggat aacctcattt tctccagcag cttttgcaaa gtcacctcga
      721 atagtgcctg gtaaagcttc ttctggacga gttgcaccca tcatggtccg ccaagtttcg
      781 attactttgg gaccagaaat gacacccaca agaactggac ctgaagtcat gaattcacga
      841 atcggtgggt aaaaactctg accaaccaag tcctgatagt gctggtcaat caactcttct
      901 gaaacctgtg aacgaaactc caatttttcg attgtaaatc cacgttgttc gatgcgcttt
      961 aacacttcac ccactagccc tctttttaca ccatctggtt tgatgataaa gaatgtttgt
     1021 tccatacccg tctcctttgt cagcttcttt cttttatttt accacatttc gtggaaaaat
     1081 ggagaaagtt ttcagaagag agaatgagag aacccgaggg ttctctcatt ctctcttatt
     1141 ctactgtttc ttccacagtt tcaacggcag tatccacaac tacttctgtt gtttcttcat
     1201 ttccttcttc ctctactgga ggattaaggt attcttcttc gttgacagca tgtggttcaa
     1261 ggttacggta acgggccata ccagtaccag ctgggatgat cttaccgatg ataacatttt
     1321 ctttaagtcc aaggagatgg tctttcttac cacggatagc tgcgtcagta aggacacgag
     1381 ttgtttcctg gaaggaagcc gctgacaaga aactgtttgt ttcaagtgag gctttggtaa
     1441 ttcccataag gactgggcga cctgtcgctg gaactccacc tgcgataagg acatctttgt
     1501 tggcatctgt aaagtcattg atatccatga gggtacccat gagaagatct gtatcacctg
     1561 gatccatgac acggacttta cggatcattt gacgaaccat tacctcgatg tgtttgtcac
     1621 cgatttctac cccttggcta cggtaaactt tttgtacttc accgagaagg tacgtttcaa
     1681 ctgacaagac atcacgaact gcaaggagac gttttggttg gatagaacct tctgtcagag
     1741 cagcaccacg cgctacttgg cccccaactt cgacacgcat acgagctgta aatggaacga
     1801 catattcacc ttcgccagtt tcacccttaa caaagacttt cttggtacga gttgatgcat
     1861 cctcttcgat agcagtaact tgtcctttaa cctctgtgat aaccgcttcc cctttaggat
     1921 tgcgggcttc aaagatttct tggacacgag gaagaccctg agtgatatcg gtatttgagg
     1981 caaccccacc tgtgtggaag gtacgcattg taagctgtgt accaggttcc ccgatagatt
     2041 gggcagcgat tgtaccaact gcttcaccaa cttcaaccgc atcaccagtc gccaagttga
     2101 taccgtaaca gtgacggcag acaccgtgac gagtgttaca tgtaaataca gaacggatag
     2161 tcacttcttc cacaccagca ttgacaattt cacgcgcctt gtcttctgta atcaattcat
     2221 ttggaccaat aatcactgca ccagtttctg gatgtttaac agttttctta gtgtaacgac
     2281 cgttgagacg ctcttcgaga gactcgatca tctcttttcc ttctgcgata gaacggatca
     2341 agagaccacg gtcagttcca cagtcgtcct cacggatgat aacgtcttgg gcaacgtcga
     2401 ccaaacgacg agtcaagtaa cctgagtcgg ctgtcttaag ggccgtatcg gtcatacctt
     2461 tacgagcacc gtgagttgag aagaacattt ccaataccga caaaccttcg cggaagtttg
     2521 aaaggattgg caattccatg atacgtccat tcggagcagc catcagacca cgcataccgg
     2581 caagctgtga gaagtttgag atgttaccac gggctccaga gtccatcatc ataacgattg
     2641 ggttcttagg atcttgatta gcaatcaagc gtttctcaag tttttcacgg gcagcacgcc
     2701 attcagctgt aacagcattg taacgctcgt cgtctgtgat cataccacga cggaattgtt
     2761 tggtgatttg ttcgacacgt ttgtgtgatt cttcaatgat ttcagccttg tcatcaacga
     2821 ctgggatatc ggcaataccc actgtcaatc ctgcaagagt tgagtggtgg taaccgaggt
     2881 tcttcatgcg gtcaagtagg gcagaagttt ctgtcgtacg gaaacgtttg aagatttcag
     2941 cgatgatatt tccgaggttt ttcttcttga atggagggtt gagctcaaga ttgctgatag
     3001 cttccttgat atctccacca agtggcaaga agtatttagc tggaacacct tctgtcaagt
     3061 tggcattgtt tggttcttgc aagtatggta gcccctctgg catgatatcg ttgaagagaa
     3121 ttttaccaac tgttgtaagc aagaccttat gtctttgctc ttctgtccaa ggcttgttga
     3181 ggctgtctgt tgcgatacca acacgtgagt ggaggtgaac ataaccattg cggtaagcca
     3241 taaccgcttc gtcacggtct ttgaagacca ttccttcacc ttcgcgacca gcttcttcca
     3301 tggtcaagta gtagttaccc aaaaccatgt cctgagatgg agtaactacc ggtttcccat
     3361 ctttcgggtt caagatgtgc tcagcagcta gcatgaggat acgagcttct gcttgtgctt
     3421 cttctgaaag tggtacgtgg atggccattt ggtccccgtc aaagtcagca ttgtaggctt
     3481 cacagacaag tgggtgcaag cgaagagcct taccatcaat caagactggc tcgaaggctt
     3541 ggatacccaa acggtgaagg gtcggtgcgc ggttcaaaag cactgggtgt tctttaatca
     3601 cttcttcaag gatatcccag atacgctcat ctccgcgttc caccaagcgt ttagctgctt
     3661 tgacgttttg cacgatatca cgggcaacga tttcacgcat gacaaatggt ttaaagagtt
     3721 caatcgccat ttcacgtgga acaccacatt ggtacatctt aagagttgga ccaacggcga
     3781 taacggaacg tcctgagaag tcaacacgtt taccgagcaa gttttgacgg aagcgtccct
     3841 gtttaccttt aagcatgtgg ctcaatgatt tcaatggacg gctacctggt cctgtgattg
     3901 gacgaccacg acgaccattg tcaatcaaag cgtcaactgc ttcttgaagc atacgcttct
     3961 cattttgaac gatgatacct ggtgcattta actcaagcaa acgagccaaa cggttgttac
     4021 ggttgataac acggcggtaa aggtcattca agtcagatga ggcaaaacgg ccaccatcca
     4081 actgcaacat tggacgaaga tctggtggga taaccggaag gatgttaaga atcatccatt
     4141 caggtttgtt tccagacttg taaaaggcat ccaaaacatc caaacgacgg atggctttga
     4201 cacgtttttg tccagtagct gttttcaatt cttctttgag ttcagcaatt tctttttcaa
     4261 gatctacttg cttcaaaagg tcttggatgg cttccgcacc catcttggca acaaatgaac
     4321 cataaccata ttcacgcaag cgctctcggt attcgcgctc tgtcatgata gacttgtgct
     4381 caagtggtgt atccttagga tcaatcacca cataagccgc aaagtagata acttcctcga
     4441 gggcacgagg gctcatatca agggtcaagc ccatacggct tggaatcccc ttgaagtacc
     4501 agatgtgaga tacaggagct ttcaattcga tatgtcccat acgctcacga cgaactttcg
     4561 tacgcgttac ttcaacccca cagcggtcac aaacaattcc tctgtaacga atgcgtttgt
     4621 acttaccaca agcacattcc cagtcttttg taggaccaaa gatcacttca tcaaagagtc
     4681 cttcacgttc tggtttcaag gtccgataat tgattgtttc aggttttttg acttctccat
     4741 aagaccatga acggacttta cttggagaag ctagggtgat ttgcatactt ttaaaacgat
     4801 ttacatcaac cactatttct tccctttcta ttctaagtga actgcttatt cttgttcagc
     4861 agcttcttct gttgcttccg cttttgttgc tttctcagct tcttcagctt caaaggctgc
     4921 tttagcctct tgggctgctt tttcgcgggc tttttcaagg tcatctacgt ggatgacatc
     4981 ttcgtccatt ccttcatcca agtcgcgaag ttccacttct tggtcatctt cgtctaggac
     5041 acgcatgtca agaccaagag attgcaattc tttgacaaga actcggaagg attctggaac
     5101 acctggtttt ggaattggtt tgccttttgt aatagcttca taggctttca aacgtccgtt
     5161 gatatcgtcc gacttgtaag tcaagatttc ttgaaggaca tttgacgcac cgtaggcttc
     5221 aagagcccaa acctccatct caccgaaacg ttgtccacca aactgagctt tacctccgag
     5281 tggttgttgg gtaacagttg agtaaggtcc gactgaacgc gcatgcaatt tatcgtcaac
     5341 catgtggtgg agtttaatca tgtacatgac tccaacagaa acacggttat caaatggttc
     5401 acctgtacgt ccatcgtaaa ggattgtctt ggcatcgcta tccatacctg cttctttaac
     5461 agttgaccaa agatcttcag agcttgctcc atcaaagact ggtgtcgcaa tgtgaatacc
     5521 aagagtacga gctgccatac caaggtgaag ctccataacc tgaccgatat tcatacgtga
     5581 tggcacccca agtgggttca acatgatgtc gactggagtt ccgtctggaa ggtaaggcat
     5641 gtcttctaca ggaacgatac gagagacaac ccctttgttt ccgtgacgtc cggccatttt
     5701 atctccgacc ttaatcttac gtttttgagc gatgtaaaca cgaaccaaca tgttaacacc
     5761 tgattgcaac tcatctccat ttacacgtgt aaagatctta acatcacgaa cgacaccatc
     5821 ggcaccgtgt ggtacacgaa gagaagtatc acgcacttca cgagacttgt ctccaaagat
     5881 agcgtgcaag agacgttctt cagctgaaag atctttctca cccttaggtg ttactttacc
     5941 tacaagaata tcaccttctt taacctcagc accaatacgg ataatcccca tttcgtcaag
     6001 gtctttgagg gcatcttcac caacgtttgg aatttcgcga gtgatttctt caggcccaag
     6061 ctttgtatcg cgcgtttctg attcgtattc ttcaaggtga acagatgtgt agacatcgtc
     6121 cttcaccaag cgttcgctca tgataacggc atcctcgaag ttgtaacctt cccaagtcat
     6181 gtaggcaacg attgggtttt gtccaagcgc catttctcca ttttccatag aaggtccgtc
     6241 agcgatgaaa tcgccttttt caacgacatc accaactttt acgagagtgc gttggttgta
     6301 agcagtacct gagtttgaac gacggaattt ttggatgtgg taaacatcca atgaaccatc
     6361 ttcacgacga acttctacct tgtcagcatc tgcgtaagta actttaccat catactgagc
     6421 aatcacagcc gcaccagaat cgtgggctgc ttggtattcc ataccagtac caacgtaagg
     6481 tgcctgagga ttaatcaatg gcacagcctg acgttgcata ttggctccca tgagggcacg
     6541 gttggagtca tcgttttcca agaaaggaat acatgctgtc gcaacggcaa ctacctgttt
     6601 tggtgaaacg tccatgtagt caacaatatt agctggatac tcttggttga ccccttggtg
     6661 acgtcccatg acaatcttct cagcaaaggt tccatcttca ttcagacgag agttagcctg
     6721 agctacagta tattcatctt cttcatcagc tgtcaaccaa acaatttcgt tcgtgacaac
     6781 acctgtttca cggtcaacct tacggtatgg tgtttgaaca aaaccatatt tgttcaagtg
     6841 tccgtaagat gacaagttat tgatcaaacc gatgttaggt ccttcaggtg tctcgattgg
     6901 acacatacga ccatagtgag tgtagtgcac gtcacgtact tcatatccgg cacggtcacg
     6961 agtcaaacca ccaggtccta aggctgacaa acggcgtttg tgagacaact cagaaagcgg
     7021 gttgtgttgg tccatgaact gtgacaactg tgatgaacca aagaattctt taactgcagc
     7081 tgttacagga cggatattga taatttgttg tggtgtcaag acttcattgt cctgaacaga
     7141 catacgttca cggacattac gttccatacg agaaagtccc aaacgtactt ggttggcaag
     7201 caattcacca accgcacgga tacgacgatt tccaaggtgg tcgatatcat ctacacggcc
     7261 aagtccttca gccaagttga ggaagtagct catctcagca aggatatctg caggagtcac
     7321 cgtacgaacc ttgtcatctg ggttagcatt accaatgatc gttacgacgc gatctggatc
     7381 agttggagca ataaccttga atttttgaag aacaacaggc tcagtcacaa cggctgcatc
     7441 gtttgggatg tagacaatct tgttcaagtc gccatccaaa tggctttcaa tgctttcaat
     7501 cacgctacga gtcataatcg taccagcttc taccaagatt tctccagttt cagggtctac
     7561 caatggctct gcaatggttt ggttgagcaa acgtgtttta acattgagtt ttttattgat
     7621 tttgtaacga ccaactgctg ccaagtcata acgacgtggg tcaaagaagc gagctacaag
     7681 caagctacgt gagctttcag ccgtcttagg ctcacctgga cgaaggcgtt cgtaaatttc
     7741 tttcaaggct tcgtctgtac gagagtccat tggattcttg tggatatctt tttcaacagt
     7801 gttgcgaacc aattcgctgt ctccaaagat atcaaagatt tcatcatcac ctgagaaacc
     7861 aagagcacga accaaggttg taaatggaat cttacgagta cggtcgatac gagtgtaggt
     7921 gatatctttt gagtcgcttt caagttccaa ccaagctcca cggttaggga taacagttga
     7981 accatagccc accttaccat ttttgtctac tttgtcgtta aagtaaacac ctggtgagcg
     8041 gaccaactga gaaacgataa tacgttcacc accattgatg atgaaagtac ccatttctgt
     8101 catgattggg aaatcaccaa agaaaacttc ttgggtcttg atttcgcctg tttctttatt
     8161 gatcaaacgg aaggttacaa aaattggtgc tgagtagcta gcatcgtgga tacgagcttc
     8221 ttctagcgtg tattttggtt ccttgatttc atatccaaca aattccaact ccattgtgtc
     8281 tgtgaagttt gaaattggca atacatcttc aaacacttcc ttaagaccgt ggtctaggaa
     8341 agctttgaat gagtcagttt gaatttcaat caaatttggt aagtcaagaa cttctttgat
     8401 tcttgaaaaa ctacgacggg tacgatgttt cccgtattga acgtcatgtc ctgccaagat
     8461 gattctcctt tgtaaataag ttccaagcct tgtcaatcag gcttttctaa tcgtcatatg
     8521 gttgtaaacc ccttatcacc gtgtcctctt gacgaatttt cagaatcttt aagcctctgt
     8581 tacaaatgct cataatcttg aaaaaaagca caaaaagagc agctaaatct gactttttca
     8641 gaagatttaa ctgctgtgag ccttgtctgg acaatatttc agacaaaacc tacgacaaat
     8701 gattacccat attataccct atttagctag atttttcaag gggtttcagt aggtttttgg
     8761 taaatttttt cccatagaaa acttggcatc acattcgaat cacgctatgg tacaaaaaac
     8821 tgaaaaaact attgactgaa aatcattttc aaggtataat aataaacgtt aaggcggtat
     8881 agccaagtgg taaggcacgg ctctgcaaaa gcttgatcgt cggttcaaat ccgtctaccg
     8941 ccttctataa cttgatttat caggtttcaa atgaacagaa agcccaattt gaagggcttt
     9001 ttttattttc cctcgaataa atacgtataa ctttaaaaac ttttggagcg agtttgtggc
     9061 agagttcttt ccatggcata attccctttt gaaatcaatt gaaaaaagct tcgtcacgcc
     9121 tggtgacaaa agcctctagt ttattctgtt tcttcttcta tttcgacttc tgtgatttgg
     9181 acttttacct tggtaacacg tccattcttc actttatcat tggttaagat aaactgtttg
     9241 ttttggctga ccaattcata gctgagtttc tcagtcgttg gaatggttcc cactcctgtc
     9301 aaataataac cagcgatggt atcaacgtca tcactttcca gctcaacatc aaagtaatta
     9361 ttgaaatcat tgagggtcat agttccttga acaatgtagg tatcctcgcc aatctgatga
     9421 acatctattg ctgctttgtc cgtttcatca tcaatttcac caacaatttc ctctaagagg
     9481 tcttccaaag tcactaaacc agccatacca ccgtattcat ccagcaagat tgccatttgt
     9541 ctttgggtat ttcgcagttc ttttagcaag tcatccacaa aaatagtttc aggtacaaaa
     9601 agtggatctt gtaaaattct cttccaaaca atattgtcaa aaccgtccac aaagcctgcc
     9661 ttaaggagac tcttggtgtg aatgattcca attacattgt ccttatcccc atcataaacc
     9721 gggatacgag aataattttg ttttaaaata ctttggataa tggcttgact atcatcctga
     9781 atatccacca taaaggcatc cgttcgagga accataacct ctcgtgccat cagttcatcg
     9841 agcgaaaaga caccttgtag catctcaatc tcatcagcat ccaatgtttc ttcactattt
     9901 gtcagcatat aggcaatttc atcacgggtc attttttcat ccgcatcatc gaatgacata
     9961 ggagtcaaat ggctcaagaa attggtcgaa gcagctaaaa gccaaacaaa aggactgact
    10021 agttttccga tcccaatgat aaccggcgct gtacgaattg ccaaggcatc ctttagatta
    10081 agagcgattc tcttaggata taattcccca aaaacgatgg aaatataggt caaaaatgcc
    10141 aaggatagaa aagttgccac ggcttgtgct gtttcgccat tcccaagcca agaggcaatc
    10201 acacgtccta gagtatcagt taaactcgcc cctgataaga ttgtaatcag ggtgattcct
    10261 acctgaatgg ttgataaaaa gtggttagga ttttctagta ccttcagcag gcggatgtag
    10321 cgtctgtctc cttcttccgc cttttgttca actcgggcac gattaagaga aaccatggcc
    10381 atttctgtgg ctgagaaaaa ggcatttaat accgtcaaga taaacaataa aacaaattgt
    10441 agcaacaaat tctgactact tgggtcttcc atagttcttc tcctaaaata gtatcttatc
    10501 ctttattata tcacaaaatt taatccaata catattattt ttttcttagc gtaacttcca
    10561 tctctctccc aaaactggaa gttagtctaa gacggatttc cactgatttc acgcgttttt
    10621 ctcatactaa aagctaggtt gtgggaaact ggaagttagt tttagaagtt actatttttt
    10681 cttagtacct attctagccc tgcttaaact agtaaaaaga actcctacat ccataagtga
    10741 cataggagtt taggcttatc ttttactgag ttacagttac ttctccagtt cggtaatcca
    10801 gttgaagtcc cttttgaaca ttgggaacta gaacattgaa ttccaattct ccatccgaag
    10861 acttggcttc aatctgtgaa gctgagggaa ctaaatcctc gtttgaagcg tagtaaaggg
    10921 ttacacggta acggacacgc ttgttttggt ccaaggcttt acgcaccttg ctttcatagt
    10981 agttttgacc agtcgaatac tcggcttgtg cctgatttgc ccaggctgtc tgaacagcaa
    11041 tgtttttagg attgcttgtt gaggcatcaa aaccatccaa accaccgatt aaggcatagc
    11101 ctaacaaatg acctctatcg actgcatggg tataagagcc ctttagattc ttgacctgat
    11161 gccaacctgg aggagtccaa gaagttgaac cattcccagt ttctttacga ttcttgtact
    11221 gacgagtggc cttagacaag agggcattag ctacggttgg aacagtttcc ttgcccactg
    11281 tctttgtttt attgtcagcg tagggcttac ttgaaacctt ggcatctaga tttgttttat
    11341 taccattgac gataaaagca cctgagccat tccactccag actccccttt atttgactct
    11401 tgactgcgtc tgttaagaca ctctctgcca atgcttgact aggagcttca gacgcttgtt
    11461 ttttctgact aagattggtt ttgggactat taggtgccga ctgcatctgc ttgatataat
    11521 agctccctgt agacaaaagc aataacacta gcagtccgat tagtgtctgt cttgtttttt
    11581 tgttcatatt tctccttatc tttagaaaaa ggctggttct ccagcctaat ttcctgtaaa
    11641 tttatgaatc aattcctgcc attttgctgg agacaggata gcccatggat cttgaccctt
    11701 gcccaagatt ccataaccta ccattagacc gattcctaga gccagagtac ctaaaatcag
    11761 tactatgatg actaaaagta aacgattgat tacgtagctt gatttcttat tcatcttcat
    11821 cgcttgcctc aatccgctga atcttagcac ctagctgcgc caacttctca tggaaaccgt
    11881 agtaacctct atccaagtga accaatttac cgaccacagt ttctccctgt gctaccaaac
    11941 ctgtcaaaat caaggctgca ctggcacgaa ggtcagttga aagaacttct gctccctgca
    12001 aaggctgtcc accaacaata cgagctgtat cacggataat ctcagaatgc aagcccatgc
    12061 ggcgcatctc ttctaggtgt tggaaacgat tttcgaaaac tgtctccacc atggttgatt
    12121 cgccttttgc aactgtcatc aaggctgtaa attgagcctg catatctgtt ggaaatcctg
    12181 ggtggggcaa ggttttcaca tgaacagctt ttagattttc tagttgagaa cgaacacgaa
    12241 ttccttcgtc ttcttcaatt acttcaacac ccatttcaag taacttggca atcaagggac
    12301 ggttgtgctc ccagacagcg tctcgaatca agacatcacc accagtcatg gcagcagcta
    12361 ccataaaggt tcctgcttcg atacggtctt ggactacatt gtgagtcgta ccatgaagtt
    12421 tctcaacacc agtaatggtt atagtctctg taccagcacc tttgaccttg gctcccattt
    12481 cattaaggag aatggctaag tcaacaatct caggctcacg cgcagcattc tcaatcactg
    12541 tcaccccatc agccagagtc gctgccatca tcaagttctg cgttgcacca acacttggaa
    12601 agtccatata gatatgagca ccatgcaagc gttctgcctt ggcttcgatg taaccagctg
    12661 tctgactaat cttaaccccc atagcttcca gacctttcaa atgaagatca ataggacggc
    12721 taccaatcgt acaaccacct ggcatggata ccttggcatg acccacacgg gcaaggattg
    12781 gccctaatac aacgatggag gcgcgcatct tgctgacata cttgtaaggg gcttcctcag
    12841 tgatgtcgcc agtagcatcc accttgacaa gatgagcttc ctcatcaaag tcaaccttgg
    12901 cattcaaacc accaactacc tgattcataa taaagacatc cgacaaaatc ggaacattct
    12961 gcaagacggt ctttccttca cttgctagaa tagtcgctgc caacaagggt aagactgcat
    13021 tttttgctcc ctcgatcgtc acgcttccta ccagacgatt atcgccacct tgaaccacaa
    13081 ttttatccat actcgtttcc tttactcttg atttcataat aatcctctaa gcgcttcttg
    13141 ccacaaatga tacaggctaa taaagaaaga actcaggatg tagcctatga caatgctaaa
    13201 aaaggctact aataaacgaa cttttcttgt attctcatct gtcactttta aaaccttctc
    13261 ccatctaaca agatccttta aaaggtaaaa actcacataa ataaagagca tatgactact
    13321 tagagtgaat aataattgaa ccatttgact attataccat cttctctgtt tgtgcgctag
    13381 tttggaaact tcactcaaaa attagggatt gtttttcaag taatcaatcg catcttgtag
    13441 ggttttaacg ggcacgattt tcatatccgt cttgattgtt ttagccgctt ctagggctgt
    13501 ttggtagttg tttttcgcgt ccggatgcgc cttttgttct tcttcgctaa cagggttatc
    13561 aggagcaaag aaaatagcag cacctgccct agccgaagct acaaccttct tatcaatacc
    13621 tccaatgtct cccacattac catcgcggtc aatggtacct gtaccggcaa caatacgacc
    13681 attacgaaga tctgggtgag ctatttgagt atagatagct agactaaaca tgagaccagc
    13741 acttggaccg ccaataccag ctgttgaaaa gctaattggg acattgctga ttacctctgt
    13801 acggtcaatc aagccgattc caattccatt tttgccattt tccaaggtga taatctttcc
    13861 ttctgcagac ttggtttgcc catcctcttc ataggtgacc ttgacggaat cccctaattt
    13921 ttgagaactg acgtaatcaa tcaagtcttt ggaactatca aaggtctgat cattgactgc
    13981 tgtgactgta tcagagatat tgagaatccc tttaaaggtt gaattatccg tcacattcaa
    14041 aacataaact ccaaagtact tgagttcgat atccttacca gctgttttta gtccttgata
    14101 cttggccata ttttgcgatg tttgcatgta gaattgattg attcgcataa attcaacatc
    14161 ggaagaacca cctgtagtct cctgagcact acgaatatct gtaaaaggtg tcaaccaagc
    14221 ataaatcata tgagctaaag tggcatgttg aacaccaacc gtaacgaatt gataggcacc
    14281 agcttcctta tcttctgtgt catttatttt aaggacttgg cgaatatctt ccgaaccacc
    14341 tggaacctct atataataag gcaagggcac tacaaatgcc aagaaagtca caatcaaggc
    14401 cgcaatgacg tataagggcc atctaatctt ttttttcatt tcttatttcc tccaaaatac
    14461 tctcgggaac atagcaggca atatcctgac caaacttcaa aagctctcta acgcctgatg
    14521 aactgatata gagatgttca ggtcgactat gtaaataaat agtctctata tcagaagaca
    14581 gctgatgatt gtagtaatca aaactggctt catattgcaa atccgacgca ttcctcaaac
    14641 cacgcactag acaagtagca cccaatcttt ttgcaacatc gaccaccaat tcatcatgag
    14701 aagccacgac ttcaacattt tccagatgtc ccaaagcctt ttctagcccc cgtttacgat
    14761 tttcgatagg aagaaatcct tgtttgtggg gattaaaaaa aataccgaca tagagcttat
    14821 caaagagtct gctcgcccgt tcaatgatat ccagatgccc atttgtcatc ggatcaaatg
    14881 agcctgtgaa taagccaatc ttatctgaca tagactgtca ccttactaat tccataaatc
    14941 ttttccttcc agatacccag acaggcaatt tcttctggaa gttcaacggc cttatccgtc
    15001 tcgcacacaa ccataacatc ttcagaaaaa agctctctct cagccatttt ttcaatatct
    15061 gctacgattt gttccttggt atagggaggg tctaagaaaa cgaggtcaaa ttccccagat
    15121 acctgttcca atgccctttc tgcatccatc ttgaggagtt gaaattttcc aatttccttg
    15181 gttatctgga tattttcagc cacgatggtc tgagccttac ggtctcgctc caccaaaaca
    15241 gcactggaca tgccacgcga tactgcttcg atagataaac caccactacc tgcataaagg
    15301 tccaagactc gtcccccttc aaagtaggga ccaatcatgt taaaaatggc tcccctaacc
    15361 ttatccgaag taggtcttgt cgtcttgcct tctagtgtct tgaggggacg tcccccatag
    15421 attcctgata cgattttcat actgtttatt ataccaaatt atagacaaaa agagaaagaa
    15481 aaccgaacct tgcggttcga ttctctacaa aatattttcg taagtatcgc ggacttcttg
    15541 aggccaaaca cttgtttgca cttctccgat gtgtctcttg cgaagtagga acatggccat
    15601 acgagattgt ccaattcctc caccgattgt caatgggaat agaccattca acaaagactt
    15661 gtgccattcc aattccaagc ggtcttcatc acctgtaatt tccacctgac gtctaagagt
    15721 ttcttcatct acacgaattc ccatagaaga caactcaaag gctccaccta aagactcatt
    15781 ccagacaaga atatcaccat ttagaccctt gtagccattc tcagactcgc ttgtccagtc
    15841 atcatagtct ggtgcacgtc catcgtgcgg tttaccatct ggcaactcgc caccgatacc
    15901 aatcaaaaag acggctccaa attctttaca aatcgcattt tcacgttctt tcggtgtcaa
    15961 gtctgggtag cgttctacca attcttctgt atggataaag gtgatttgtt ttggcaagat
    16021 agactcgatg tcatagcggg cttcaacagc tagctcagtc aggcgaatag ccttataaat
    16081 cttctcaact gtttctttta gataaacgat gttacgctta ccatttggga taaccttctc
    16141 ccagtcccac tggtcaacat aaacagagtg ggttgcatcc aaggaatcct catctggacg
    16201 aagggctttc atgtggacaa agagaccctc tccttcacca aagccaaaac gagccaaggt
    16261 gtggcgtttc catttagcaa gtgagtgcac cacttcataa gtagcatcag ggatttggag
    16321 aaccttgacc gatactggat tttccacacc agacaggttg tcctgcattc cgtcaccgac
    16381 cttactcaag ataggacctt gaacttcgac aacttctagc ttatctttca aatactgggt
    16441 aaaagtgttt ttgacaaagg aaatttcttc ttgttgatgg ataaaacttt tcttcataga
    16501 caactcctca aaaatttaat aaacgtatta tacacctatt tccaagaaaa gaaaagagaa
    16561 aatttaaaaa aatcagtgtc actcaaaaca ctgatttcat agacctttta gtcattgcga
    16621 ccaaagatac gtagaatact taggaaaaga ttgataaaat caagatagat gctgagagcc
    16681 attgacacca cccaacctgt cgctacacga ccttgtgatt gttcataggc gaggcgaatc
    16741 ttttggttat cccaagcaat caaccctgaa aaaaccaaaa ccatggctac gctaatcata
    16801 taatcaaaga agccactagc caagaaaata ttgactacca tagcaatcag taaaccaatg
    16861 agagctgcca tcattgctcg accaatccca ctcaagtctt tcttggtaaa gataccaact
    16921 gccgccatga caaagaagag aagggcgctc gatacaaagg cagataaaac tgtacccgga
    16981 gtatagaaag ccaccacaaa actaagggta aagccgttta aaacggagta aagtaaaaat
    17041 actggaagag cagctggact atttcttgaa gccatgctac tggcaacgaa aaccaaagcc
    17101 aactccgcaa aagtagcaat ggtcaaccag agacgcccct gcatcaaaaa gtaaaccaac
    17161 tgagactgaa agaccgtcaa cataaggcct gataccaaag cagatagtcc gattcccaga
    17221 ccaacaaagg cataaacctt agcgtaaaat tgattgagac ctgcacggtc atgtataata
    17281 gtgtgattca tccatttctc cttttctgtg aacatctttc cttgattata acaaaaaaag
    17341 ttaaaattag cttaaatgga agattaaaat accggctgca accgcaacat tcaaactctc
    17401 ggcctgcccc ttcatgctaa tatggaccaa ctggtctgca ctttcagcca taaggggact
    17461 aattccttga ccctcatttc ccataactag tacaaaattt tctatagaag gcagttctct
    17521 gtaatcaaca gaatctttag atagggttgt tgctagcact gggatagcta cctttttagt
    17581 ttcgtcaaga agcgcttgac tagtcatccg gtaaatgggc agatggaaat gactaccttg
    17641 catggaacgt agggttttga gactgtagat gtctgccgac ttatctgaaa caatcactcc
    17701 tgtaaaacct gctgcatccg cagttcgaat gatagttcct acattaccag gatcttgcac
    17761 atcttccaaa aacaagaact tgccctgact caaatcagct tgtcctactt cttctctttg
    17821 aaccacggca acaattccct gtggagtctg agaatccgcc aaatctagca aaatatcctc
    17881 tgacacccag acagtttgcg aaaaagtagc taactgatct cgataatttt ctagggtaaa
    17941 gattttctca atcgtcactc cagcttgaac agcttcttca aacaagtgcc agccttcaat
    18001 caaataggct gacttgcggt attttttttg gtgtaatttc ttggtatttt ttaccacaga
    18061 attggctttt gaggttataa tagtcataga aatattataa cacaatcaaa ggggtttggt
    18121 atgcaaaagg ttagaatgat tgcccaaggt agggtacagg gagtcggctt tcgttggggt
    18181 gtttacagct tggcccttga aatcggtggc atcacaggtc gggtatggaa taacgacgat
    18241 ggcacagtgg aaatcttagc ccaagcagac tcatctgcta tcatggcaaa atttatccaa
    18301 gaaatccgaa aaggaccgac acctttttca aaagtaagct acttagatgt caaactaagc
    18361 aactttcctc cctactctga ctttaaaatc gcaaattagg tctccagaac tattgtatat
    18421 tttgtaaaaa aacagtagaa tagaaaggta taatttttaa agaaggaata aaaacagtga
    18481 aatctattaa acgttttgca ttctcggcta tgggagtggc tatgttgctt gtcttgactg
    18541 gctgtgtcaa tgtcgataaa accacaggtc agccaacagg atttatttgg aatacgatcg
    18601 gagcgcctat ggctgaagcc atcaagtact tcgctactga taaaggtcta ggctttggtg
    18661 tcgctatcat tatcgtaacc attatcgtac gcttgattat cttaccactt ggtatctacc
    18721 aatcatggaa ggcaacgctt cactctgaaa agatgaacgc tctcaagcat gtccttgagc
    18781 cacaccaaac acgtctcaaa gaagcaacta ctcaagaaga aaaactcgaa gcccaacaag
    18841 ccctctttgc cgctcaaaaa gagcacggca tcagcatgtt tggtggtgta ggatgtttcc
    18901 ctatcctcct tcaaatgcct ttcttctctg ctatctactt tgctgcccaa catactgaag
    18961 gggttgctca agcaagctac ctaggcattc ctctaggttc tccaagtatg attttggttg
    19021 cctgtgctgg tgtcctttac tatcttcaat cgctcctttc acttcacggg gtagaagatg
    19081 aaatgcaaag agaacaaatc aagaaaatga tttacatgag cccactcatg atcgtcgtct
    19141 tctccctctt ctcaccagcc agtgttacac tttactgggt tgtcggtggt ttcatgatga
    19201 ttctccaaca gtttatcgtc aactatatcg ttcgtccaaa acttcgcaaa aaagtccgtg
    19261 aagaactagc caagaaccca ccaaaagcaa gtgctttctc taaaccaagt ggacgaaaag
    19321 acgttacccc tgaacaacca actgctatca caagcaagaa aaaacacaaa aatcgcaacg
    19381 ctggaaaaca acgttcgaga taagaagaaa aaggcttagc tgatttgcta agtctttttg
    19441 caaatcaaaa gcccgatgtt tccatcaggc ttcttttcta tccatgtaca cgtttcatat
    19501 aatcttgata actttcggta tccatgagtt ttttagcgtt cttgacgcga tctgctgttg
    19561 gtggtttgac tccttcgagg gaatatggaa ttccaagttc acgccacttg aactcaccca
    19621 tggtgtgata aggtagaatt tcaaacttat caacattttt gagggtcttg acgaacttac
    19681 caagttcaat caagtcatca tctctgtctg tcaatcctgg aactagcacg tggcgaatcc
    19741 agacaggttt tccaatatct gatagatact gggcacaagc caagatattt ttattagttt
    19801 gtctagtgac aatcttgtgc tgttcttcgt tgatttcctt gatatccaaa agaaccaagt
    19861 cagtgacagc catgagtttg tcaaacttct caaggtaacg tggtttatta cggaaaggaa
    19921 gagcacaggt atccaaggta cagtggattc cttgttcctt agccttggtg aagagagcaa
    19981 tcaggaaatc aatctgcaag agagcttctc ctccactgac tgtaatccca cccttatttc
    20041 cccagaaacc acggtagcgc aaggcctctg tcaagacatc atctaccgtc cgttcacgtg
    20101 acttattgga ctccatagcc caagtgtctg ggttgtggca atactggcaa cgcatgtgac
    20161 agccctgcaa aaagacaata aagcgaatac caggcccatc tactgaccca aagctttctg
    20221 tcgaatgcac cattcctgtc acttgtccat aatcaattgt ttcttcagac atatcgttac
    20281 cttccttgaa aacgttttat agttttatta tatcatgact tgaaggaaaa acaagatttt
    20341 tgcctatttt ttagaaagca atctgttttt caatttcatt ttcaatctat tatcagatta
    20401 ttcttcaaaa tcgaagccat ataaggttgc aaaatagtcc tcagggcgct ctgcacggcg
    20461 gatttgacgg gctttacctt cttcggtata gaggatttcc gcagaacgta atttggcatt
    20521 atactggtag cccattgaaa atccgtgggc acctgtatca tgaatgacca gcaaatcacc
    20581 gatttctgta tgaggcagtt cgcgattgac tgcaaattta tcattgtttt cacagagtga
    20641 accaaccaca tctaccgctt cagctggtcc atctggatgg gtcacgttgc taatatgatg
    20701 gtaagctccg tacatagctg gacgcatgag gttgactgct gaggcatcca cacctagata
    20761 ggtacggtag gtttccttct tatgagtcac tcttgtgact agagcaccgt gaggtgccag
    20821 cataaaacga cccaattcgg tgaaaatctt gacctgacca agacctgctg acgtaagaac
    20881 ttcttcatac accttacgaa ctccctcacc aatcaaggcg atatcgttcg gctcctggtc
    20941 tggacgataa ttaacaccaa taccgccaga aagattgata aagtctagcg aaatgcccaa
    21001 cttttccttg atttcaacag ccagttcaaa gagctgacga gccaactctg gataatagag
    21061 atgggtcacg gtattggacg ctaggaagga gtgaatccca aaagtcttgg ctcctttttc
    21121 cttcaagata gcaaaggctt caaagagctg gtccttggtc atgccaaact tagcctcccc
    21181 aggattgtcc ataatgtctg tccccagttc aaaaacgcct ccaggattat aacgacaaga
    21241 gatgatttct ggaatgcctg ctactctctc cagatgttca atatcttcaa aggcatccaa
    21301 gttaatggtc gcacccaatt cacgtgcata ggcgtattcc ttgtctggcg tgttgttgga
    21361 agagaacata atctcagaac ccagaaagtc cagtttatgg ctcatcaaaa gctctacata
    21421 actagagcag tccacaccac aaccttcttc ttggagaatt ttcaaaatag ctggagttgg
    21481 agtagcctta actgcaaaat attccttaaa gcccttgttc cacgaaaaag cttggttgac
    21541 ggctcttgcc ttctcacgaa tccccttctc atcatacaag tgaaagggag tcgggaactc
    21601 ggcaacaatc gcttctaact cttctctatt gataaatggt gttttcataa gcttccttct
    21661 attctgtttg caaagaaagg ctgggacaat cgttccaacc tttagttcta tctcttattt
    21721 atcttcgtca aagatattgc caacctcaac atcgatggct tggttcttga catcaatatt
    21781 agttaccttc aagagtgact tgtagtcaaa ctgcttttca cgttcttctt gggcattgtc
    21841 cgcaaagacc gctacacctg ccagttctga gtcgaactcg cgcaagagac taatcatacc
    21901 gttgaccgtt ccgccacctt tcaagaagtc atccacaatc aagacacggc tgcctgcctt
    21961 aagactacgt tttgaaagga acattttctc gatacggtca ccacttgaac ctgaaacata
    22021 gttgacgcta acagttgaac cttcggtaat tttcaggtca cggcgcacaa tgacaaaaga
    22081 gacattgagg acattggcaa ctgcatttgc aagtggcaca cccttagttg ctacggtcat
    22141 aaccgcgtca attttttggt ccataaagct tttggcaata atacgaccaa tatttttcaa
    22201 gatggctggt gtgctaagca aatcagacag atagatataa ccacctggca agatacggtc
    22261 actttctgac aacttggtac gcaagtcttc aaccatttcc ttagcatcct gactcgaaat
    22321 agacggtgtg aagatgacac ctccgccagc cccagtcact gtctggatat gaccgatttc
    22381 aatttcctca aaggcgcgtt tgataatgac gatatcttct gagatggatg atttagcaga
    22441 ctcatacttt tcagcaaaag tattgagact agttagttta taaggattat taatcaaata
    22501 gttggaaatg acaaccatcc gatcacttct tcttaatttc atttctattt cctattccat
    22561 ttttattcaa aaaatcaaaa agcaaactag aaagctggtc gctggtggtt caaaacactg
    22621 ttttgagatt gtcgatagaa ctgacaaacc ctgtaatata cctgcatata tacatacgac
    22681 aaagcgatac taccctagtt tgaagatatt ttcgaagagt attcattttt gtcttttact
    22741 tattatacca tattcacata aaaaaacgaa cattcttatc ctaaaaaatg ctcatttttc
    22801 ttaaattatc aatctaaatc tggtttatag aaggaacgat tatccatagc gaagatttta
    22861 ttggtcatct ctcctttatc caccaaagcc agagctgttg acatcatcat catgcttgca
    22921 tccagattgt caatcatatg gataatctct gcctccataa tacgtggacg gactggactt
    22981 ccatattcaa gcaagccgtg gtgactgagg atgacatgac gaagcaaaac gacttcttcc
    23041 ttggtatcat cgatgccgag ttccataact gtcttggtaa tttcgctatc aatgagagcg
    23101 atatgtccaa gaagattacc tcgcactgtg tactctgtct ggtctggccc cgtcaactcg
    23161 atgaccttag ccaagtcgtg caacataatc cccgcataga gcagactctt attgagctga
    23221 ggataaactt cgctaatagc gtctgccaaa cgtaccatgg tcgccgtatg ataagccaac
    23281 cccgtttcaa aggcatggtg gttggtcttg gcagctggat aggagtagaa ttccttatca
    23341 tacttggtgt agagatttcg gacaatccgt tgccagacag gattttcaat tttgaaaatc
    23401 atttgcgaca tgtagtcacg aatttccttg acatcaactg gtgacttgac cttgaaatcg
    23461 gctgggtcat tgggttcacc agcttgaggc aggcggagag taatttgatt gacttgaggg
    23521 gtattgttat aaacttctcg gcgtcctttc atgtggacaa ccttacctgc ggtaaaggcc
    23581 tcaatgttat gaggttgggc atcccagagc ttcccatcaa tctcgccact atcatcttgg
    23641 aaggtaaagg ctaggtagtt tttcccagct cgagtttgcc tcaggtcagc tgatttgatt
    23701 aggtaaaagc cttcaaatag ctcatctttt ttcatgtgac taatcttcat attcttcctc
    23761 attttcttga aaatggagta gatcaagcgc aggctcgcct tctgacaact caatgtgacg
    23821 gagcgtccgc tcgatagcta tggtacgacg gtttaataat tcatcaatat tgccagaggc
    23881 atgttggaga tgtttttgtg ccttgaccag aataccacca aacttgccaa actcggtctt
    23941 gacactggca agagtcttgc tgatatggtc ggcactcttt tggatattaa gggtcttgaa
    24001 accaactgat agggagttaa gaagggctga tagggtactt ggtcctgcaa caataatctg
    24061 ttcttcccgt ctcaaatcat caaagaagac cggattgcgg acgatttctg agtagagacc
    24121 ttctgtcgga acaaacaaaa ctccaaaatt ggtcgtccga ggtggtgcta tgtacttgtt
    24181 cctaatatcc ctagcaaaac gcttgacact tgctaggagt gacttacgac agcgttcgat
    24241 ttcatccttg tcacctactt cataggcttc ttctaagcgg taataatctg ccagtggaaa
    24301 cttagagtca attggtaggt agacgtattc ttggtcgcct tgtccgggta acttgatggc
    24361 atactccact cgttcactag agttttcaac cgttgcgtat tctcgttcgt actgggcagg
    24421 tgtcatgatg tcttcaataa tttgccccag ttgcaattct cccagaatcc ctcgcgtctt
    24481 ggttccagag agaaccttgt taagagctcc gacatcacgg gcaactgtct gcatttctcc
    24541 aagaccacga ttgacagact ccagttgttt agaaactgtc tcaaaggaag cctgtaagcg
    24601 tgtctgcaag gtcttttcta gtttttcctc gaccgtctgg cgcatttgtt ccaaacgttg
    24661 ctcatttgat tcctgcaagg cttggagacg ttggtctgtc ttgtctctag tttggaggag
    24721 attatctgtc atttcttgac ggacttgggt caggccttgg tgcaattcaa tccgcacttc
    24781 ttgcaaacgg tcgctgacag ccacttccaa atctttttgg tctaactggc tggcttgtct
    24841 ggcttggtca aagcggtaat ccaactggtc tgacaaatga tctgcctgat cctccaagct
    24901 cttacttaag tgtttctcct gcctatcctg tctttgccaa atcagaaaga gaccagctag
    24961 gttggcaatt aataatagaa taagtaaact ttccatccta cctcctgtcc ttgctatgca
    25021 gtacgaccac ataaccatct gggcaagtca ccgacacttc cctatctata tattcgttag
    25081 aagcgtacac ttttttaaag aaaaaattct cctctgtcaa ctcatactta gctccaagaa
    25141 tagtcagctg gctatcccga actggcataa aggctagata gtcgtagtct gaacgaggtt
    25201 ctagctgact ggtcccttct gaacaatagg caatcaaatt ttgcccatcc tcaatttcta
    25261 tttgacgcat atagggtgcc aacttaggat tgctaggtag aaagacattg gccaacatat
    25321 ggtcaatacg gccacccaag gcaccgaaaa tagtgacctc agcctgagga ttttgttcaa
    25381 agatggttaa gagagccaat tccagatctg tatcatcctt ttctggtcgg gcttggacaa
    25441 aatgctgggc acgtttttga atcacctgtc gctcttcttc cgtcacagaa tcaaaatccc
    25501 caactgctag agcaagaagc aagtcttctt ccaagaccca gagcgagcct cgatccaccc
    25561 caacaaaagc atcaaaatct gtccgataat gaccgcggtc tccgcctgca aaaacggcaa
    25621 ccctagtcca gttgttttct gagagtttgt actcgctcat tgacatctcc cttaaagaca
    25681 taggaacctg ctacaaaaac ggtcgcacca gcttctttag cttgggcaat agtttggtca
    25741 tcaatcccac catccacttc gatttcaaag ttcaaacctt tttcctcacg aagagcaacc
    25801 aactcacgaa ccttatccat ggtttctggc agaaaggctt gcccaccaaa acctggatta
    25861 accgtcatga ctaaaacttg gtcaactaga tgaaggacgt gcttgatggc ttcaactgat
    25921 gtgccaggat tgataacgac tgaaggctta actccgagtg aacgaatttt ttggagggcg
    25981 ccatgaatat gaggcgttgc ttctacatgg atactgatga tgtctgcacc tgcacgcgca
    26041 aaatcttcca gatgatgctc agggtttgac accatcaagt ggcaatcgaa aaccatctta
    26101 ctatgaggac gaaggctctc gaccacacct gcaccaaaac tgatttgcgg tacaaaatga
    26161 ctgtccatga tatcgatatg ggcatattct gccccagttg cttctagacg tttgatttca
    26221 cgttcaaagt tggcataatc tgctgccaga attgacggag caatcttgta ttgagacata
    26281 ggtttctcct tattttggaa tttttttgct gactttttta taggtttctc tacgattttc
    26341 aatttcacta aggaattgca ggtaattgtc aaaacggaag gttgcaataa caccctcttc
    26401 aacagctggt ttgacggcac aagacggctc atgggtatgg gtacaagtac ggaacttaca
    26461 atctcggcta acagtagcaa tctctgggaa agcctgattg aggtcttcag cccttgatac
    26521 ttcatagtcc aaggatgaaa atcctggtgt atctgcgatt ttacccccgt tgagattgta
    26581 aaaactaaca gctcgagtgg tatggcgacc gcgacctaga ctgtctgaaa tttctcccgt
    26641 ttcaagattg aggtctggtg cgattttatt gagaagagtt gacttcccaa cacctgtctg
    26701 ccccataaag accgtaacct tgcctgttaa caaagacagg agttcctctt tactggtcac
    26761 aaagtcatag ccgatgtcac cataggtctg ctggtaaaaa tccagttctc ccctatcttc
    26821 caacaaatcc attttggaaa tatagacaat gggatggatg cccttgtgct ccaaaagaac
    26881 caagaaacga tccagcaaat tgctgttaaa atcaggttcc ttgacggaca tgattactac
    26941 agcttgatcg atattgacaa taggcggacg aaccagactg tttttccgtt cgtgaatttt
    27001 gaggatatag ccttctgaat tttcctcggc agagaaatct acccagtccc caacataagg
    27061 ggtatggcct tttttacgga aattcccacg cgcgcgtgtt tgataaacct ggccatcact
    27121 ctccacatag tagaaacctg ccaaggcttt aatgatttgt ccctgcatct tagagtcctt
    27181 gccctttaag tgcgtctgct agaccggcaa attctgccaa gctgagagct tccccacgca
    27241 cacttggtga caagcctgcc tggtccaaag ccttggtcag cttgtccttg acctcttcag
    27301 tcttaccaaa gtaacctgtc aagttattcc acaaggtctt gcggcgatgg gtaaaactag
    27361 ccttggaaac cttaaagaaa aagttctcat cttctactgc tacggctggc tctggacgac
    27421 gcaccatttt caagatggct gaatccacat ttggcgctgg cacaaagacc gtacgaggca
    27481 cgataaaggc aaccttggct gtcatgtaat actgcacggc gatagacaag ctaccgtaag
    27541 ccttggtgtt aggctgggct gaaatgcggt ccgctacttc tttctgcatc atgaccacaa
    27601 actcactaaa aggaatgcca ctctcaatca agtgcatgag aataggcgtc gtgatgtagt
    27661 aaggcaaatt agccactacc ttgattggca ggttaggatt tttaaaattt tggatatgtt
    27721 gcgccaaatc aaccttgaga atatcttcgt taactacagt cacattatca aaatcacgca
    27781 gggtatctac caaaattggc accaaacggt ggtcaatctc aaaagccatg acttgggctg
    27841 cacgctcagc cagaaactcc gtcaaggcac caatacctgg cccgatttcg atgacattga
    27901 cctggtcatc aatttcagcc gtatccacaa ttttttgaag gatattggta tccgtcagga
    27961 aattttgccc gaaggacttt ttaaaggtaa aaccgtgacg ctccagcact gccttggtca
    28021 cgctataatc tgcaattctc atctattctc ttttctatta tctgttacta ctattgtaac
    28081 acattcccct tgtattttgg gaatgaaaat cataccaaaa aactatcttt cctcatgaag
    28141 aaagatagtc ttggaaatct ttaaaagtgg ccttaacagt tctctcgaaa catgcgttca
    28201 tactcttcga aaatctcttc aaaccacgtc agcttcacct tgtcgtactc aagtacagcc
    28261 tgcggctagc ttcctagttt gctctttgat tttcattgag tatcaaaaaa atcagcttct
    28321 tgataacttc tattttcggg tagggtcaaa tccacatcct cctccacatc atccactgtc
    28381 agttcaaccg tttgaggtaa atttttcaaa cgataatgct tttgccttta cccttcaata
    28441 ctagcaaaat caagcaaata gccatgcact aggatttgaa ccaaaaggag atgattggtc
    28501 atatttttat cttctaaacc acctctggca ctaggataat cagataccct gcgaatacgg
    28561 attttttcac acatgagcaa gtttcctcat atcaatgatt tcatcagcct tattccagac
    28621 taggggatta tgggtcgcaa tgatgataat tcgattttca tctttcaaat ccaccaagag
    28681 attcataacc tcctctgaat tttcaggatc aagagctgct gttggttcat ctgccaaaat
    28741 caagggtgga tttttcaaaa tagtttttgc aagggcaact cgttgggcct ctcccccaga
    28801 taaagtatag attttttgtt ctaaatccaa ataccctaga ttaacttttt ctaaagcccc
    28861 cacttgcctt tccaaacgtt ctacttttga gattttctga ccaacaaaac ccaaatccaa
    28921 attttctttg attgattggt tttctaagag gccgaaattt tgaaagagat agcccatctg
    28981 gtctcgaaaa tactcacgag taggaatggt ttttaaatct ttcccctgat agagaaccct
    29041 tccaccatct atcttttcta gctttcccaa gatattcagc agcgtcgtct ttccgcttcc
    29101 actctttccg attaaggcat aaaccttgcc cttctccagc ttgagattca aaccagagaa
    29161 aatcgcgcgg tcattaaatt tcttttccaa tccttgaata tcaatcatct tattttcctt
    29221 tcaatactgc catgctacca gcttcttctt ttttgtcctg ccttactaaa atcaagaggg
    29281 cgttaagcgt aaacaaagct acaactagag cgctaatcaa accatctctt gtcaaaatac
    29341 tagataggac taggccaagc aagagaactc ctccttgcgc cagtaaatac ttgccatgaa
    29401 gttcatagat tgtcatacca gcaagacgtt taatcataag ctcccgtctg aactgctcaa
    29461 aatagagaag attcatggaa tcaaataaca agatagccgt agacagggtc aaaatcgtcc
    29521 caataaggag agagtaaaac tccacccgtt tgtcatttag taccttggca aaaaatagct
    29581 ggctttttac caagtaagaa accttgtgat acagaccttg ctcttttaga gctgtgatgc
    29641 tgtctccata tcgatctagt ttcaaggcac tattagccgt agttccccac aacatccctg
    29701 caacaggtct tgttccagtc gcttgcggcg ttagaactac aataatcgga tcttttaggt
    29761 actggcgtgt tgtcttgtac ccatcattat agaggaaacg ttcctgtcct gtttctgtaa
    29821 aagctagcct tacctgtggg aggtagtgtt tctgactcgt cacttctaca ctttcagatg
    29881 aaaagttttg caggtaatct gtaaacaatc cttggtagta gacagactgc tctcgcaagc
    29941 tctcaggcaa gatcagccca aactctccct cagacaagtt ttgcatcttg tccataaact
    30001 ctgaagaaac ggtaatcttt tcttctatca gatagcgtgg tgagacatag ataacattcc
    30061 ctgacggtgt gtagtcactg agacgattgc catctaggtc cacttctgct ccatctgaga
    30121 aattgtcaac attgctcata atataaaaag agtctgtatt ggctaaccgt tcttcagtaa
    30181 atgtctgcca ctcacgatta tccttacgcg ttccttcttc atcggcaaat gcactagacc
    30241 aaccaaagga tagacggtaa cggtctgagg actggctcca tttattgcta gctctctcca
    30301 tttcctgcat ttcacggtag tggggtagga gagctgtcgc actcgatccg accaccaata
    30361 cagctaagag ttgccccacc atcatcaatg tcatcatacg tttgagaggg agtttccctt
    30421 tcaatagatc caccagacta ttttcctgta aaccaagtag atagacgaca cttagtaagg
    30481 tagaaatccc tgccaaggtc aatccataaa gtagaagagc aatgatgacc agttgcaccg
    30541 ttgccataaa caaggcacct tgataccaga gaatccccaa tcccaaaaga ctggatacca
    30601 gcactgagca gataagctgt ctcacatctt ctaacactgg tctgagagca actccaaaca
    30661 agctctcacc agctattaag cgaatccctg cctgacgaag ggatttgatc cgataaatca
    30721 gggtcagact cataaaggtc agcagaaaaa tagctaaact cagtagcacc ataggggtgg
    30781 ccgtcaatag taagactatc gaaaatggat cttctccatt cgaaacaaag ccttgataac
    30841 caagctcttt caaggtggtc tgtaagctca ctccatccaa acttcctgac acaatcaagt
    30901 aagaccctaa taaatcactc gtttctgcac tctccttgga ggaaatggtc agaccttctg
    30961 gaagctttcc ctcaccataa gtggcatagg taaagcgtgt ttctccagct tcatttggct
    31021 caacgattcg acgagcaatg agactattgt gctctaccgc caagtgactc aaagcctctg
    31081 tcacctcttc ccgactagct actggttgat ttatcatcat tcctgtcaca tcaacagaag
    31141 gatagttacc aaataaaatc tcttctcgat ggtcaacgga agttatcacc atataaagcg
    31201 ataccaatac cattgaaatc aaaataaata aacgtttcat catttcctcc aaaaagttac
    31261 ttggtcactt agtgagaagg tgaccaagta aagctaaaca atagggctat accattctaa
    31321 acattatagt agaatgcaac tttctctccc caagaagtac gaatccatgc acgagaagtc
    31381 cctccagcac cagcatatcc cttgtcagat gaaccagttt ttctgctaac aactgttgaa
    31441 ctatggtatt ttgaagggtg atagtagttt gagtaagcac caccgttacc tgaaccataa
    31501 gtccaaacac caccttctgg gtattgaacg gctgcagagg caactgctac acttccacct
    31561 aatgttgctg caatgctcgc tacaagagct aattttttaa ctgtttgttt catattgata
    31621 ctcctctatt tttgattaca agattgttga gttacttgct cctctttcca ttatcaacgt
    31681 tgatactatt atattaccaa atgatattct aaaattattt gtttttctct aaattgtcaa
    31741 aatagcaccc tgaaatgaac ttttatagtc attatactcc atctttatca cactatcaag
    31801 gacatcaatg tccttaaaat ctaactattt catattattt ttagcttata tctaaaaaaa
    31861 cagttctaaa gacgaacttt agaactgttt tgatacgagg acaaggacat ttttgtcact
    31921 gattcactat gtttataaat attttttgac atcctcttgc cattcctctg tcaatttctt
    31981 tactagaaat ccatctccaa ttagcttcgc aaatgtttta gaagactgat aaaatgattc
    32041 agctaaacta aaatctcttt ctactcttaa tgcttgcttc cacaaaaaca taaatacaag
    32101 aggtttcttt tgataatctt gagttttatc cataatttct tgtaaacacg atagataatc
    32161 attaaaacaa tcagttactc ctaccttttc aagacaacac attcctgaaa taagagtatc
    32221 tctaattata aagtaattct ctatttgagt taccttcttc tgttccaaaa gaaagagcat
    32281 tagcttttcg atttgattta taaatttggc aagatctttt ctaatgagca tttgataaaa
    32341 aaacaaacga atcaacaaca tatcatttat tgaataagct tctttttcta taatctgagg
    32401 catatgttcc tcaagtatta actctgcata ttcaggcctt ctagttctag aagtatccaa
    32461 acacgcctgc aatacttcac atgctaattg ttcttcttta ggaagattat caaagtatgt
    32521 tttataaatc tcttccaaac acgcttcctt cttatcgtac tcctcttctt taccatagat
    32581 tggttcacgt aaaatctggt atttcaattc taaataagca gaaggaagag ctgaaaaatc
    32641 cggcataagg ctataaactg gaactcctag ccggcgagca atataggcta acttgggcaa
    32701 actcggttgc gaagctccac tttcaattcg cgacagttga cgaactgtca gttcttgctc
    32761 atctccacaa aaatctggac gactaattcc tttttctatc cgaatctctt taattttttg
    32821 accaattaac atcagacgcc tcctcttcta cctgcttcga aaaatactgt gaaacttaaa
    32881 aaattgtaac ggctacatct ttcctactca taagatttca tagcttcttc cacttctgcc
    32941 aaagtaaccc caaacaactc taggcgtttg aggagttgct tgccgttaga atagccgatt
    33001 cggagagtct ctccgagata ttctctacgc ttacggctgt ctgcccctgc tagaaaacca
    33061 aggcgaatca aatcgctacg actaatgtca aactgactct catgttcaaa ttgttctgtc
    33121 acctgagcta gagccgtttt caggtcttca tagctggcat gctcaattcc cagagaacgc
    33181 cccttggtct tggacttggg aacagcttca tctcgcttga gaaaggcatg ctgaactgtt
    33241 ggaatggccg tcataatcat gcgccgaatc cgctccccat taaaatctgg gtctgtaaag
    33301 acaatgactc catgacgttg gtgtagacgc tgaatccgct ctatgtcctg gtcattgatg
    33361 gcagaacctc gagtctcata ggtctccaca tcgaaataac gcttgagatt gaccgtatca
    33421 tcacgacctt caaccacgat aacttgggaa attctctctt tcattacttg ctgtccaatc
    33481 caaaaatgcg ttctgcattt gcagtcgttg ctaccgccag ctcttctgtc gtcataccac
    33541 gcaagtcagc gataaagtcg accacatagc gagtataggc tgttttattt tcacgaccac
    33601 gcttgggtac aggtgctaag taaggcgcat ctgtttctac caacatcttg tccaaaggta
    33661 actctttagc tgcttcttgg aggtcagttg ccttcttgaa ggtcaccact cctgagaagg
    33721 aaatggtcat accaagatcc acaaacttct ctgcccactc aagcgtccct gaaaatgaat
    33781 gcatgatacc accacgagga ccaacgccct cactcttgat aatctcatag gtatcttcca
    33841 gcgcatcacg ggtatggaca acaaaaggca aatccaagtc cttagatagc cgaatctgac
    33901 ggcgaaaaac ctgctcctgc acctctttgg gcgctgtcat ccaatggtaa tctaagccaa
    33961 tttcacctaa agccacaacc ttgggatgtt ttaacttatc caacaagtaa gcctcaactt
    34021 cctctgtata agtaccagct tctgtaggat gccaaccaat agtcgcatag agctgctcat
    34081 actcatctac caactccaag gcacgctcaa tcatcggttt atcaaaacca acaatattca
    34141 tctgtatcac acccatctca gcagccaagg caatttcttc tgcctcacga cctgcaaatt
    34201 cttctacatt caagtgtgta tgtgtatcaa aaatcatctc ttctaacctc gttttctatc
    34261 ttctattata ccaaaaaaga ggaggggcac ctaatttttc ggtttcccct cctctcttca
    34321 atagagagct attctgctat cttttctatc cgatattgcc catctcctat tccacagtta
    34381 gagacagaag agattggcta cattgataga atattcctat tcagctaaag tatgtgatta
    34441 tcttgggttc tcacttttct cacccatcac taggattgat gacttctcaa aatccccctt
    34501 ataatctaac tttaagtaga gaatagaatt ttctagctgt tctattttct acgtctagtc
    34561 tttcttccta gcaaagcaaa accacttgtt gccaccacta gaccaagact agcaagtgct
    34621 gcacttgatg ctgaacctgt gttaggtaat tgtttgccag caggtgactg gtaggtaaca
    34681 tcttgcattg ttcctgcagt tgcttgcggt gcacttgttg tcttaggagc agcattagga
    34741 gccactagtc tcttaggaac tgtaaccatg gcaatggctt gcactccaat cgtttctgct
    34801 tccttcacat cttccatagt tttcgcattt tcaatctctt tgagagctgc ttgtttttct
    34861 gcttccactc ttgctaaaag ttctgctttt tctttatcag aaagcggtgc gcctttgatt
    34921 tcatcctgct tgtccttggc tgctttttca atggcatttt tagctgattc tttttcagta
    34981 gctaattgct tagaagcttg tgattgagct gagttttgtg aacctgtgtg agctgatcca
    35041 cccgcctggc taccaccgcc ttcattcgca ttagcatctg agcttccaat attgcctccc
    35101 ttatctccac ctggtgtagt ttctagctta tactctggtg taacttcttg agttacagat
    35161 tcacctttcg cagattgttg aactgtatct tttcctagaa tcgtcactac tgaaccatct
    35221 gggaatgtga ttgttgctgt accatctcca gctacattga ttgtcgctcc gtctaatgct
    35281 gaaccatttg cttgtaaaat agcaacctta actttttctt catctgttaa atgagttata
    35341 tcttttacat ctactctttg agcaggtgct ttaacagttg atttttcagc agtcggttta
    35401 gtgctatctt gtgcttttgg atcttgtgct accaattgat ttcctggaat tgtaatagct
    35461 gaaccatctt taaagacgat tgttgctgta ccatctccac ctacttcaac tttatagtaa
    35521 aataaaataa taacaggaca aatcgatcag gacagtcaaa tcgatttcta acaatgtttt
    35581 agaaacagag gtgtactatt ctagtttcaa tctactataa catcgcttcc gaatccattt
    35641 gcatctactg aactttttta caaaaataaa aatcagtaga ctcgagttcc tactgatttt
    35701 tgatagaatt cgtttggatt atgcagccaa aactttgcgt cctttacgac gacgagctgc
    35761 caatacgcga cgaccatttt tagttgacat acggttacgg aatccgtgtt tgcgcgcacg
    35821 acgaagttta cttggttgat aagtacgttt cacgatgaat acctcctcat agattttgta
    35881 ttcgtttagc cggctataaa gtgatcagtt actaaacata ctttactatt ctatctgatt
    35941 ctttcacttt tgtcaatagc tctaggcaaa tgtttccagc tttttcgaat gcaagcccta
    36001 tctacgatac tgtttcaaga aacgagtcat cttttcttgg atttgggcta actcatcaac
    36061 acgaggaagg taaacgatac ggaagtggtc tggttcctgc cagttaaagc ctcgaccatg
    36121 aaccaagaga accttttcct gcttcaagaa atcaaggaca aactgctcat catcatcgat
    36181 acggtacata ttgcggtcga tttttgggaa gatatagagc cccgccttgg gtttaacggc
    36241 agacaaacct ggaatatctt gaatggcatt atagatgaaa tttctttgct cgtagattcg
    36301 tccaccagga agaagcaatt catcgactga ttggtgaccc cccaaggaag tttgtacgac
    36361 ttgttgggcc aaaacgttag agcaaaggcg catattggac agcatattga gcccttcgat
    36421 atagccctta acatgagtct tagggccaga caagaccatc caacccacac ggaaacctgc
    36481 tatgcggtgg gattttgaca gaccattcat gctgacacag aagacatctg gtgccaagct
    36541 cgccacaggc gtatgcacat gtccgtccat taccatgcgg tcatagattt catccgcaaa
    36601 gataatcaaa tcgttttgac gggcaatctc aataatctcc agcaagagtt ccttaggata
    36661 aagggctcca gttgggttat ttggattgat aaggacgatt gccttggtat tggaagtgat
    36721 ttttgacttg atatcgtcaa tatctgggta ccattcaaca gcttcatcac agatatagtg
    36781 aacggcattt cctccagcta ggctgacagc cgccgtccat agaggatagt ctggcattgg
    36841 cactaagacc tcatccccat tgtccaaaag cccctgcatg gacatgacaa tcaactcact
    36901 gacaccattt ccaaggtaaa tatcatcaat atctacgttt gggaatttct tcagctggca
    36961 atactgcatg atggccttac gggctgagaa aatccctttg gagtcagaat agccttcact
    37021 atcacgcgca ttcataatca agtcatgaat gacctcgtct ggcgctgtaa agccaaattc
    37081 tgctggattt cctgtattca gacgtaaaat cttttctcca ttcgctcgca tccgcatggc
    37141 ttcttccaat acaggaccac ggatatcata agcaacatgc tctaacttac tagacttgtt
    37201 atattctttc atcttgtttc ctcaattcat caggatagta acattatacc actagaaaga
    37261 gaatgcgaca agtttactga aatgtgttac tagtttcgta tagaagaaaa accttgctaa
    37321 aggcgaggtt aagaacgtag agatagcagg tattttgcaa agacacatca cataccaaaa
    37381 gataaaccta gaaaaagcaa gcctagaaag gagtcataaa gaagattaaa catgaggaaa
    37441 agcccccata tcatcaagta atcccaacgc ccacttcgtt ttgcaactag aaataagatt
    37501 agatggtaga gtacatgaaa gactaaaaat ccaataaaac ttggataaag aagcggtacc
    37561 agactctcta attgacagat catgatcact tttaccaaga ctgaaactag gataattcca
    37621 taataaagga aatttgattt ttgaaaagag tttttcatca ttctcctttc ctcctatcct
    37681 ttcttttatt ttatcatata tttatataga gtttaagccc taatattctt ttgaaaaata
    37741 ctttttttgc tttacttcta tagtgaaaag gtttacaatt atagtaagaa aatttcagga
    37801 ggtttcatta tggcacaacg ttaccaaaat atcatggtcg caatcgatgg ttctaaggaa
    37861 gcggacttgg cttttgtcaa gggagttcat tctgctctac gaaacgacgc taaactcacc
    37921 atcgcacatg tcattgacac acgcgctctc caaagcgtat ccacctttga tgctgaagtt
    37981 tacgaagaac tccaagtcga cgctgaaagt ctgatgaaag agtacgaaaa acgtgctaaa
    38041 gatgctgggg tagcagatgt tcatatcgtc attgaaatgg gaaatccaaa gaccctgcta
    38101 gcacgtacta ttccagatgc cgaggaagtg gacctcatcc tcgtgggcgc aactggtctc
    38161 aacgcctttg aacgcctctt ggtcggctct tcatctgaat acatactccg ccatgctaag
    38221 gtcgatttgc tggttgtgag agaacaagaa aaaaccttat aatcacaaag aaaaggagcc
    38281 cctagctcct ttttgtttac gatttatttc tctctttatg gcgttcgtaa gccttgagct
    38341 ggcgatgcag ttccttttta atagcaggtt ctggagcata tttttcttcc caattatctg
    38401 gttttaagat tttatgggtc actggatcaa aatgagcctt gccatctgga aaaattttcc
    38461 ccatattggc ctgatggaca atatcaaaaa tacgttctgg gtccaccccc atcaagacaa
    38521 aactgccgta ggtgaagtaa agcgtgtcaa tcaaggcatc cacttgccct atcaaatctt
    38581 gctgagcagg tgtcttcttg gctactttac ctgctgcctt atcaagggcc tgatgaagtt
    38641 gcgatacagc ttgaccaaaa tcttcttcag aaggactggc tgctcgaaca aactccacca
    38701 attcttctat tttaaaacca gccctatggg ttgcaccctc taaatcccaa gctcgaggtt
    38761 cttcttgggt tcgttcatcc atcatgtggt ggaaggtctt gaccttattg aaatgatagt
    38821 cacggctgac aaagactttt tctgaagaca aaacaccaaa atgttccaag gccttgtgga
    38881 tcccatcttg ttgattgcta gtggtaatgt gcttggcagc ttccttgaca ctgctactac
    38941 catttcccat agcgaccgac ataccgacgc cagccagcat ttcaaggtca ttatctgagt
    39001 caccaaaagc catgacttgg ttgaggtcaa agccatattc tttcccaact cggcgaatgc
    39061 cttctaattt agaatttccc tgattgatga catccgatgc aaaaggattg ctacgtgtca
    39121 atttcaagtc ttcaaaatca gctgccgcct tctcagattc ttctggtgtc atcagcatca
    39181 aaacttggta gataggctga ttcatcaggt gaagcaggtc ctcttccttt tggggaacaa
    39241 ccttgctgac catgcgatta aaagactgac tcaccgtccg agttaaaaca gagggaacga
    39301 agcgactaat tcgttgggaa aaagaaccca gaccaaagga catgatttta gaacccaaca
    39361 tggcatcctt ggtccctaga gcaatctccg tgccctcttt tttagcatag ctaattagat
    39421 ggcgcaaatg taacttggaa atagggctcg tgaacaagac tctgtcttta ctaaagatat
    39481 actggccatt ataggttacc gcaaaatcca gatccaaatc gtccatcaat tccttaacaa
    39541 aaaaaggtcc tcgccctgtc gctacgccaa ctagtacccc ttgttctttg acaatcttaa
    39601 tcgcgtcctt agtggatttc aaaacactct tgcgattgtt gaccaaggtt ccatcgatat
    39661 caaaaaaaac agctttgact tccatcctat tccaatctcc ccttttgtga tacaatgatt
    39721 ataccacatt tcagaaagag tgagtaaatc atgcctaaga aaatccttgt tttacatacg
    39781 ggtggaacta tttccatgca ggccgatgct tctggcgctg ttgtgacgag ttcagataat
    39841 cccatgaacc atgtgtccaa cccacttgaa ggaatccaag tccacacctt ggactttttt
    39901 aaccttccaa gtccccatat caaacccaaa catatgctgg tcctctacca gaaaattaaa
    39961 gaggaagcag ataactacga tggagtggtg atcacacacg gaaccgatac tttagaggaa
    40021 acagcctatt tccttgatac catggaagtt ccccatatgc ctatcgttct aacaggagcc
    40081 atgcgtagct ccaatgagct cggtagtgat ggtgtttata attacctaag tgctttacga
    40141 gtggccagcg atgacagggc tgctgacaaa ggagttttgg tcgttatgaa cgatgaaatc
    40201 cacgctgcca agtatgtcac caaaacacat acgactaatg tcagcacctt ccagactcca
    40261 acacatggcc ccctcggtct caccatgaaa caggaaatcc tctacttcaa aacagctgaa
    40321 cctcgtgttc gctttgacct tgatcacata caaggtttag tccctatcat ctcggcttat
    40381 gctggtatga cagatgagct gattgatatg ctggatttag aacacttgga cggtttgatt
    40441 atccaagcct tcggagctgg taatattccc aaagaaacgg ctcaaaaatt agaaagcctt
    40501 ctgcaaaaag gaattccagt cgctctggta tcacgatgct ttaacggtat tgccgagcct
    40561 gtttatgcct accagggtgg gggcgtacag ttgcaaaaag caggcgtttt ctttgttaaa
    40621 gaactcaacg cccaaaaagc tcgcttgaaa ctcctcatcg ccctcaatgc cggactaaca
    40681 ggacaggctt tgaaagacta tatggaaggc taatactctt cgaaaatctc tgcaaaccac
    40741 gtcagcgtcg ccttaccgta tgtatggtta ctgacttcgt cagttctatc tacaacctca
    40801 aaaacatgtt ttgagctgac ttcgtcagtt ctatctacaa cctcaaaaca gtgtgttgcg
    40861 cagcctttaa ccagccgcct agtccgctct atggtattca ttaagtcaac atctcttgtt
    40921 taagagcaca aaatcaggaa atcttctcga ttccctgatt ttttctattt acgttttcgt
    40981 gttgagctac gttctgtcaa accatgaggt aagagaactt cacgttcttc caactcttcc
    41041 ttatgcataa tcttggtcaa catacgcata ctaatggcac caaggtcata aagaggttgg
    41101 gcaatcgttg tcaagtttgg acgggtaaag cgtgagattt gtgaatcatc actagtaata
    41161 atttcaaaat cttctggcac agaaacaccc ttatcagcca aaccgttcaa gactcctgct
    41221 gccaactcat cacctgtcac aactgctgca gttgcatttg atgaaatcaa acgctctgct
    41281 aaggcgtaac catcatcata gctatattta gattcaaata ccaaaccctc actataagtg
    41341 attcctgctt ttttcaaggt ttccttgtag ccaactaaac gaaccttacc attgatgtca
    41401 tccactagcg gaccgctaac gaaagcaata cgctcatttt ctttagcaag gtaactcact
    41461 gcatcaattg ttgcttgctt atagtcaata ttgacacttg gcaactggtg ctcaacatcg
    41521 acagttcctg cgagaacaat cggagtacgt gaacgcgaaa attctgagcg aattttatct
    41581 gtcaagtgat aacccatata gataatgcca tctacctgct ttgaaaagag ggtattgaca
    41641 acagaaactt ctttctcgtt atcttcatcg ctattagcta ggacaatatt gtacttgtac
    41701 atttctgcaa tatcatcaat ccccttagcc aaactcgaaa aataaccatt ggtaatattt
    41761 ggaatcacga caccgacagt ggttgtcttt ttacttgcaa gaccacgcgc aactgcattt
    41821 ggacgataat ccaaacgatc aattacctct agcacttttt tacgggtatt ctcttttaca
    41881 tttttattgc cattgaccac acggctgacc gtcgccatgg aaacacctgc ttcacgagcg
    41941 acatcataaa tggttactgt atcatctgca ttcattcctt ttcctgtcct ttctatctca
    42001 cacattcttt tacaagtaga ggtactgatt gaagctctat atctacttac aaaagtgaag
    42061 atgtgaaaat ttcgttttca tatttctact tattccattc tatcactaat tgtaaacact
    42121 ttcaagtgtt ttttgaagat tgattgaaaa aatttcatag aaaacctagg tttagctcct
    42181 tgctaccacc ttagactaaa caaaaaggag gaaactaagc cctcctaaag ttatagtaaa
    42241 atgaaataag aacaggataa atcgatcagg acagtcaaat cgatttctaa caatgtttta
    42301 gaagtagagg tgtactattc tagtttccat ctactatagg tattgttcca ttcactaccg
    42361 tcaattttag cacatagtct tcatgaaaat attatatcat cataaccaac cagattcttt
    42421 tgcgatatta gctgcctctg ttcgattacc agcatccagt tttgaaagaa tattggtgac
    42481 atagtttcga atagttccgt ttgagaggta aagctgatct gcgatttctt ggttggataa
    42541 gccccgggcg attcccttta agacagcaat ctcttgttct gtcaacggat tgggacgggt
    42601 catcaccact tccatcaatt caggcgaata ctccttgcgt ccttcgagga cggtgtgcaa
    42661 ggtttgcatg aggtctgcaa tgcttcgttc ctttaataca taagcatcca ctccagcctt
    42721 gaccgcacgt tcaaaatacc cagcacgctt gaaggtcgtc accacagcca cctttgtttc
    42781 aagcctttct gatcgtatcc actccaagac ttcaagacct gtcttaacag gcatttctac
    42841 gtcaaggatg gcgatatcta cagactcctt ttctaatagt tggattgctt cttgcccatt
    42901 cttggcttga aggacagact ccacatctgg ttgaagcgtg agcaattgac acatggcatc
    42961 tcgcaacata ctttgatctt ctgcgactaa tactttcatc ttagtttctc tccttataag
    43021 gtagtcgaac ttgcacttcc gttggatgtt tctgactgat tacacttact tctcctgaaa
    43081 atggaaaaac acgatctcgg actgtatgga gctcatctcc ttttagaaaa gcaaagccgc
    43141 agccatcatc acttactgtt aaaatgagtt ccttctctgt ccgttctaat tttaagtaag
    43201 ctttagacgc tttggcatgt ttgatgatat tggtcaccaa ctcaagcaaa atcatagaag
    43261 ccattgaatc caattcttga gtaaggctag cagtatctag ttggttatct gtttccacct
    43321 caattccagc aatttctaac atctttttca cagtctctag ttcggatgtc aaagttctag
    43381 acttaagatt ttccacaatg gttcgaactt cacacattga ttctttgcta atttgctgta
    43441 tttctcttaa ttccttttcc acttgtggat aagcctgcat ttgaaatagc tgcaaggcta
    43501 gatctgtctt gacactaagc atagcaaagg tatgtcccag actatcatgc aaatcctgac
    43561 cgatacgatt gcgctcattt tctgctagca atagatttat ctgggtattt tgcttgacct
    43621 gagcttcttt caaatcctcg acaaggcgaa ttcgaaccga gcccaaagtc atcaaatcga
    43681 caaaagtaag aattacaagc atatagacta gaaactcaac ttcgattctc tgaaaaatca
    43741 aaagtcgccc cacaacaagg acttgagcaa ggagaaatgt ccatacatgt aaagacttta
    43801 aactacgtac gccaaaatga taaattaaga gattggaaag gaaaaagaaa aaccagatat
    43861 aattcccagc aacaaaggcg gtattcccag ctacatagac cagcatgagc ccccagaaaa
    43921 gccaagatag gcgctggttc ttagttatta aaacacccaa atacgtcact acaaatagaa
    43981 tatcaaccaa taaatgccaa gcaggaagct ccccaatcac tacaggtagg atgggaaaaa
    44041 gcataaaaat caaactggtc caaaacatat agtgtatgct tttcagtctt tcaagcatta
    44101 agcattctcc ttatgacctt gaaggtaaat agtcaaacca aataaaactg ctgaaaaaac
    44161 aagtaaataa actgtggctg atagattgat gtcaccctcg tttaagaagg tcttgagcaa
    44221 ctccatcaat tgataggtcg ggagacactt accaactgct tgcatccagt ctggaaataa
    44281 agaaatgggc atccagagtc cgcctaaaac agccaatcct agataaagaa gattgcccac
    44341 aacagacatc agctgactag ttggtaagag agtcaaggtc aagccaagtg ctacaaaagc
    44401 aatactcccc acaatcagca aaatcgcagc tccaacccat tttactagag gcatgtctac
    44461 acctcttaca aaatgtccaa ctgtaaaaac aaccagaatt gagaccaaat aatcaaccag
    44521 catacttgtt atctttgata gataatattc taccatattt acagggctat gacgcaatgt
    44581 tttctgccag ttgttcatct tatcggtatg taaaacagct ggaaatgaga ggatagttgt
    44641 cgacatcatg gaaaaggcag tcatggagat gaggtaatca cgcataaaat tcgcgagttc
    44701 acctggtgtg tcctgataga taccagaaaa aaataaatag aaagccgtcg gcatccctac
    44761 cgacaataga taatagatta attgtcgttt ggtcaataaa aattctatct tactaagtgc
    44821 tatccatcgt ttcatcttag ttatctccct tctgcgtctc ttcaaagatt gtattcaaca
    44881 aactacgatt attaacttcg atttcttgca tcctacatcc tgcttgggct aatagttccc
    44941 agaaagcatc tgcttctcga gtgactactt gtaaagaatc ttgctttagg gtccagtttt
    45001 caaccaaatt tgactgctct acgacttcct tgtaagctat aggaaggata aagtgctttt
    45061 ctatttcctc gctacgcata gctagaggcg tcgtatctcg aatcaactct cccttattta
    45121 agagcaaaat gcggtctgca gtgtgttcca cttcctcaat ataatgggac gaatagagaa
    45181 tggtaactcc ctgcgctttt agatcctgaa caatttccca aaaacgttgg cgggttgagg
    45241 tatccatggc cgcagttggc tcatctaaaa agacaagttt tggtcggcca atcaaggtca
    45301 agacaaaaga gaaaagacgc ttttgcccac ctgacaattt ttctgccaat tgctctttct
    45361 gttgcttgtc aaactgcaac agttgatcga tttcctggtt gctcaaggga tttggataaa
    45421 tgctttgaaa gaaagcaacc aactctttga cctttaattt ctgaacgatg acattttctt
    45481 gaggcagata acctctaata tagtctaact gagaactcgt cactgacaag ccttggatgg
    45541 atacttgacc gcttgtgacc agtttatctc caagcagaca gtccaagagt gtggtcttcc
    45601 cagcaccatt tggcccaatc aaggcgacgc attcaccttc agctacctca aaggaaatat
    45661 ccttcaaaat agcctttccc ttgatgtttt tatgtaatcc ttgaacctta atcatgtcca
    45721 tgatattctc ctttcaacca ctccattccc ataggaaagg cgataaaaat cataaatcct
    45781 agtccccagg caccacggat gaattggcga agcaaggctt gatcaaacca acctgtaaac
    45841 atttctacca accataccac tagtgatagt ccaataaaaa gatagagaaa cgcttttttc
    45901 atttttcaaa ctcctttttc acatctgaga ctaatttcaa accttctcgg ataagccagg
    45961 acatcattcc aaatcctgca aatagctccc aaggaaaatg atagaaatct tcatccaatc
    46021 ctgagaacat gagataagtc atgactcctg ctgctactaa actcattgcg acaatcattt
    46081 tatttttcat ctcttcttcc tccgtttcat acttcaatta tagacttttg aagttggcgg
    46141 agctagatgc ttctgtcact agaaaatatg acaaatgtca taaaaattct gtacaaaaca
    46201 agcaagatac actatataat aaaacacaag tagaaaaaat ctaaggcagc tttcaaaaga
    46261 gatatcaaac ccaattcaca ccataatgta aactaatact tatttaaaat caaaaagagc
    46321 ggaaattttt atcgcacaaa cacatatatt ataagcagag cgaaaaactc ttcaattact
    46381 ttcttaaaag tttgtaagaa ttatacaatc tgttaaattt taatttatgt acctaaacta
    46441 cagtattcat tgaacaaatt aggaaacaaa aaagtatacg ctgctaaaat gaattactga
    46501 aattcaaaaa agagagaagc aaactgattc tctcttaatg tatataatat ctagttaaaa
    46561 caaaaagata cgcttacgta tctctgaaa
//
LOCUS       DAVHLA010000009        44790 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVHLA010000009 DAVHLA010000000
VERSION     DAVHLA010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44790)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44790)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44790
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.009"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(442..2169)
                     /gene="ezrA"
                     /locus_tag="VVO77_000639"
     CDS             complement(442..2169)
                     /gene="ezrA"
                     /locus_tag="VVO77_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEU5692691.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAESYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2251..4197)
                     /gene="gyrB"
                     /locus_tag="VVO77_000640"
     CDS             complement(2251..4197)
                     /gene="gyrB"
                     /locus_tag="VVO77_000640"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEU5692692.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFTPDPEIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4212..4775)
                     /locus_tag="VVO77_000641"
     CDS             complement(4212..4775)
                     /locus_tag="VVO77_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU5692693.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTSFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEVISNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4860..5414)
                     /locus_tag="VVO77_000642"
     CDS             complement(4860..5414)
                     /locus_tag="VVO77_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEU5692694.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGNLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5425..6648)
                     /locus_tag="VVO77_000643"
     CDS             complement(5425..6648)
                     /locus_tag="VVO77_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEU5692695.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPRLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6685..9135)
                     /locus_tag="VVO77_000644"
     CDS             complement(6685..9135)
                     /locus_tag="VVO77_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEU5692696.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSCRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVVSLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9335..10264)
                     /locus_tag="VVO77_000645"
     CDS             complement(9335..10264)
                     /locus_tag="VVO77_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU5692697.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARNLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVR"
     gene            10404..10691
                     /locus_tag="VVO77_000646"
     CDS             10404..10691
                     /locus_tag="VVO77_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEU5692698.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10725..12059)
                     /gene="ciaH"
                     /locus_tag="VVO77_000647"
     CDS             complement(10725..12059)
                     /gene="ciaH"
                     /locus_tag="VVO77_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEU5692699.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12049..12723)
                     /gene="ciaR"
                     /locus_tag="VVO77_000648"
     CDS             complement(12049..12723)
                     /gene="ciaR"
                     /locus_tag="VVO77_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEU5692700.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(12832..15378)
                     /locus_tag="VVO77_000649"
     CDS             complement(12832..15378)
                     /locus_tag="VVO77_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEU5692701.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15501..15941)
                     /locus_tag="VVO77_000650"
     CDS             complement(15501..15941)
                     /locus_tag="VVO77_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEU5692702.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(15916..16785)
                     /locus_tag="VVO77_000651"
     CDS             complement(15916..16785)
                     /locus_tag="VVO77_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HEU5692703.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFSELTNTEANCLVGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSLIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLDRILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKIDFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(16763..17263)
                     /locus_tag="VVO77_000652"
     CDS             complement(16763..17263)
                     /locus_tag="VVO77_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU5692704.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELTNFMVHHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVND
                     EKSTCP"
     gene            complement(17274..17972)
                     /locus_tag="VVO77_000653"
     CDS             complement(17274..17972)
                     /locus_tag="VVO77_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEU5692705.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDAYKPLLEQTAQEIQEIFEINYMTPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(17965..18201)
                     /locus_tag="VVO77_000654"
     CDS             complement(17965..18201)
                     /locus_tag="VVO77_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEU5692706.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTIEQNGLALEVT
                     PYFLINVSGEGEGFSMWSPTACDVLATDWVEVHD"
     gene            complement(18301..19227)
                     /locus_tag="VVO77_000655"
     CDS             complement(18301..19227)
                     /locus_tag="VVO77_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HEU5692707.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCKLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSQAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(19302..20117)
                     /locus_tag="VVO77_000656"
     CDS             complement(19302..20117)
                     /locus_tag="VVO77_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692708.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(20121..20441)
                     /locus_tag="VVO77_000657"
     CDS             complement(20121..20441)
                     /locus_tag="VVO77_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEU5692709.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            complement(20603..20683)
                     /locus_tag="VVO77_000658"
                     /pseudo
     CDS             complement(20603..20683)
                     /locus_tag="VVO77_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(20727..22724)
                     /gene="metG"
                     /locus_tag="VVO77_000659"
     CDS             complement(20727..22724)
                     /gene="metG"
                     /locus_tag="VVO77_000659"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEU5692710.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(22848..24107)
                     /locus_tag="VVO77_000660"
     CDS             complement(22848..24107)
                     /locus_tag="VVO77_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5692711.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNVDEIANIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(24109..24810)
                     /locus_tag="VVO77_000661"
     CDS             complement(24109..24810)
                     /locus_tag="VVO77_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5692712.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(24794..25993)
                     /locus_tag="VVO77_000662"
     CDS             complement(24794..25993)
                     /locus_tag="VVO77_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEU5692713.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            26279..27625
                     /gene="gor"
                     /locus_tag="VVO77_000663"
     CDS             26279..27625
                     /gene="gor"
                     /locus_tag="VVO77_000663"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEU5692714.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFNFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESIAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            27822..28358
                     /locus_tag="VVO77_000664"
     CDS             27822..28358
                     /locus_tag="VVO77_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEU5692715.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            complement(28559..28774)
                     /locus_tag="VVO77_000665"
     CDS             complement(28559..28774)
                     /locus_tag="VVO77_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEU5692716.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            28872..29192
                     /locus_tag="VVO77_000666"
     CDS             28872..29192
                     /locus_tag="VVO77_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692717.1"
                     /translation="MRHKFQQVLDKIHDFLNGHDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFAKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(29223..29561)
                     /locus_tag="VVO77_000667"
     CDS             complement(29223..29561)
                     /locus_tag="VVO77_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692718.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(29573..30292)
                     /gene="trmD"
                     /locus_tag="VVO77_000668"
     CDS             complement(29573..30292)
                     /gene="trmD"
                     /locus_tag="VVO77_000668"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEU5692719.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(30282..30800)
                     /gene="rimM"
                     /locus_tag="VVO77_000669"
     CDS             complement(30282..30800)
                     /gene="rimM"
                     /locus_tag="VVO77_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEU5692720.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELTLFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(30830..31618)
                     /locus_tag="VVO77_000670"
     CDS             complement(30830..31618)
                     /locus_tag="VVO77_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU5692721.1"
                     /translation="MKRFEVSTEIGSLSVTYKKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKCQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGRNHHYLQWSESEKIAAIIRELSE"
     gene            complement(32195..32434)
                     /locus_tag="VVO77_000671"
     CDS             complement(32195..32434)
                     /locus_tag="VVO77_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEU5692722.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(32454..32726)
                     /gene="rpsP"
                     /locus_tag="VVO77_000672"
     CDS             complement(32454..32726)
                     /gene="rpsP"
                     /locus_tag="VVO77_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEU5692723.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            32896..33105
                     /locus_tag="VVO77_000673"
     CDS             32896..33105
                     /locus_tag="VVO77_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692724.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERDLDTWLLSPKPVPKRNMDL
                     LADDSLAGDIILLWRIQFGTFTTET"
     gene            33587..33799
                     /locus_tag="VVO77_000674"
     CDS             33587..33799
                     /locus_tag="VVO77_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692725.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEDFQDDDEIPTII"
     gene            33883..34686
                     /locus_tag="VVO77_000675"
     CDS             33883..34686
                     /locus_tag="VVO77_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEU5692726.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGNGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(34742..36283)
                     /locus_tag="VVO77_000676"
     CDS             complement(34742..36283)
                     /locus_tag="VVO77_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU5692727.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(36285..36767)
                     /locus_tag="VVO77_000677"
     CDS             complement(36285..36767)
                     /locus_tag="VVO77_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEU5692728.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVCFCFTPQEQSTVGVGTPGIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNVLNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            complement(36767..37852)
                     /gene="rlmN"
                     /locus_tag="VVO77_000678"
     CDS             complement(36767..37852)
                     /gene="rlmN"
                     /locus_tag="VVO77_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEU5692729.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERVSHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMTIGARHITVSTLGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDSVEQALE
                     LTELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGT
                     DIDAACGQLRSNTMKRDRQKAVAAVNP"
     gene            complement(37873..38403)
                     /locus_tag="VVO77_000679"
     CDS             complement(37873..38403)
                     /locus_tag="VVO77_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEU5692730.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKGQRHFVIRQK"
     gene            complement(38559..39164)
                     /locus_tag="VVO77_000680"
     CDS             complement(38559..39164)
                     /locus_tag="VVO77_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEU5692731.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            complement(39337..40374)
                     /locus_tag="VVO77_000681"
     CDS             complement(39337..40374)
                     /locus_tag="VVO77_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEU5692732.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKADSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            complement(40408..41343)
                     /locus_tag="VVO77_000682"
     CDS             complement(40408..41343)
                     /locus_tag="VVO77_000682"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEU5692733.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            complement(41896..43086)
                     /locus_tag="VVO77_000683"
     CDS             complement(41896..43086)
                     /locus_tag="VVO77_000683"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEU5692734.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            complement(43301..44644)
                     /locus_tag="VVO77_000684"
     CDS             complement(43301..44644)
                     /locus_tag="VVO77_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU5692735.1"
                     /translation="MSFTKFQFKNYIREALEELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
BASE COUNT        13263 a         9798 c         8099 g        13630 t
ORIGIN      
        1 ctcgtaaaca aagaggtttt agaggcctat ttaccgtgga ctaaagttgt acaagaaaag
       61 tgcaaataag aaatctccag attaggaact atccgtgagt tctctagtct ggagattttt
      121 caatagactt cgttattgga cggttaccaa gttactcaaa gtacagattt gaagctgcag
      181 ataagactga cgaaatcact ttaatactaa atgaaaatca aaaagcaaac taagaagcta
      241 gcctcaggct gtacttgagt acggtaaggc gacgctgacg tgatttgaag agattttcga
      301 agagtataaa acactgtttt gaggtggtgg ataaatcggc tgggtaaaaa ctcaatctca
      361 ggagaaaatg aagtaaatct ccccgcaact atagaaaaag atttgattct gctcctcaca
      421 caataaaatc tttttctttt attaaaaacg aatcgtttca cgtgttttct catatgaggt
      481 aacaaagcga ttagttacac caggctctgc cacttccaat gcttgagaaa tcttgtcaaa
      541 tgaagcgtga taatcaaatt ctttttcaaa aatatctaaa gcttcgttaa atgcttcttg
      601 aatgcgttca tcaaatgagc gatagcggtt agaatattgc aagagttgct ctgtcaaagt
      661 tgcatattgt acaatattat aagtttccgt ttctaaagct tccatatcat tcgttgcaat
      721 ttcaagaact cgggtaacag attcaatgtt aatcattttt tgttctaact caaccattaa
      781 atcctcggta ttattgcttg ccgtaaagaa taacttcaag aaagtttgtg gaatacctgg
      841 cagattgcgt ttttccatgt atcgcttgat agtatggaga cgattgacat aaacattggc
      901 cttttgacgt gcattaatat catctttctc aatttgtgtc aggcgctcac taactgaaat
      961 ttgctcatct tcaatatctt ttagttgagt ttgtaaatcc tcaagatttt cttcaagaac
     1021 tgaataagct tgggttggtt cttcttgatt cgaagttacc tcaacaatag ctgcctcaaa
     1081 actctctaat tctgtctgaa tacgacgaac atggcttgca gctgtctcag gaagtaaata
     1141 ggtcttgttc aaacgtgcaa tatcttctcc caataaagta ttattctctt tcatatgttg
     1201 aaggtaagtt ggaagagttg caagtagatt ttccactact ttctgagcag caatttctcg
     1261 agtaaaaata tcatacaagg cattgatttc ctcttgtgcc tgtccattct catattcggc
     1321 attatccaat tccaactgac gaatattctc ttggtttttc ttgaatgctt cataaagcaa
     1381 gtggaaacgc gcttcaatat ccgtttcaac aaaatgataa ttagcatcaa ttagtttacg
     1441 ataaccggct tccaaatcct gtaattgatc tggcaattct gtagaaagcg tcgtaaccaa
     1501 ggctggaaca cgatccacaa tatgacttaa ggccaaaatg tgattttctg tattatccaa
     1561 aatcactgcg gcttccacag ggtcacccga tgaattcaag gttacaaatt gtgaaaattc
     1621 agattggata ttttctaatt gtttttcaat ttcatccaag gcttgaccat actgttctga
     1681 attttcagca actctatgct gaagttcctc aaataaatcc aaagcatgaa gaacacgacc
     1741 actattttta gattcttgct tctctaagtc tgccaaagca ttgcgaattg ccgcaatatc
     1801 ttcttcaatc aaagtaattt gactctcaat ttggtcaatt tgatgactgg ccttgagaaa
     1861 acgaaatgaa tggttatagc tctctgcttc aaagagatta ttttcaatat cggcaaaaga
     1921 gttgagagat aaatcgaccc atttttgatt ccattcacgg aaagccactt gactttgtcc
     1981 aatcaagtgc atatttttta cagcttctac ttcatcattt actggaagat tgtatagttc
     2041 ttcttttctt tcttctagtg cctctaatct cccctcgttt cgcttacgta gaaagattgc
     2101 cactacataa gccagaacta aaatgactgc aattgcaacc attaaataaa ttagttgtcc
     2161 attagacata tcaaactcct tttttacttg aaacaatcgt aacgattata tcatattttt
     2221 tagaccaagg gaactacttc tccctatttt ttagacatca agtgtactat agacagcatt
     2281 ttcttcgata aactcacgac gaggctctac tcgatccccc atcaacatat caaagatttt
     2341 atctgcttct gcagcatcat ctacagaaac tctagccatc aagcgatgtt cgggatccat
     2401 ggttgtttcc cacagctgat gatcgtccat ttcacctagc cccttataac gctgaatagt
     2461 cggtttggta cgaccttcac tataacgggc taaagcttct tggagtttga tttcttgatc
     2521 tgcacccggc tggatatatt ctttaatctc gcttccaacc ttgacaccat agattggtgg
     2581 ttgggcaata taaacataac cagcttctag gattggtttc atataacgat aaatcaaggt
     2641 taaaagaagg gtacgaatgt gggctccatc gacatcggca tcggtcatca aaacgagttt
     2701 ttggtaacgg gctttcgaaa catcaaattc tgcgccaaat cctgttccca tggctgtgaa
     2761 aagactacga atttcttcgt tagctagaat cttatccata cttgcttttt caacgttcaa
     2821 aatcttaccg cgaattggaa ggatagcctg aaactcacgg ttacgaccag atttggctga
     2881 tccaccagct gagtctcctt cgacgatgaa gagttctgtt tcagcagggt tattagaaga
     2941 acagtctgct agtttccctg gaaggttgga aatttccaaa ccagattttt tacgtgtgac
     3001 ttcacgcgca cgcttggcag ccacacgagc cttggcagcc aaaattcctt tttctacgat
     3061 acgtttggca atctgtggat tttccatgag gaaatcggag aaggcttcac tgaagaggcg
     3121 attggtaatc ttgaccactt cgctatttcc caatttggtc ttggtttgtc cttcaaactg
     3181 tggatttggg tgtttaactg agataactgc agttaagcct tcgcgaacat cttcccctgt
     3241 taggttgtct tcattgtctt tcagtaactt atttttacga gcataatcat tgataacacg
     3301 tgtcaaggct gtacggaaac cttgttcatg cgttccacct tcatgtgtat gaatattatt
     3361 ggcgaaactc atgacatttt catggtaacc agttgtgtac tgcatggcta cctcaactgt
     3421 gatatcatcc atctcaccgt ctgtatagat tggtgtatca aagattacat ccttgttctc
     3481 gttgatatat tcaacgtaac tagcaatccc accttcataa tgataatgct tggtttgttc
     3541 caaaccttgg cgcttatcag tgatagaaat ttgaagaccg cgatttagaa aggccaactc
     3601 ttgaatccgt ttatttaatt tatcaaaatc aaagattgtt gtttcagtga aaatttctgg
     3661 gtccggtgtg aagtgaaccg ttgttccagt tctatctgta tccccaacca cctcaaggtc
     3721 tgcaacaaca tgaccacgac ggtattcttg gtaatgaatc ttaccgtttt tatggacatg
     3781 aacgtctaat tgagtggaaa gggcattaac tactgacgac cccaccccgt gaagaccacc
     3841 tgaaaccttg tatccaccac cgccgaactt tcctccagca tgaaggactg taaagacggt
     3901 ctcaacagca ggacggcctg ttttttcctg aatatcgact gggataccac gcccatcatc
     3961 cacaacagta atcgaatcat ctggctcaat aaaaacttga atatggctgg caaatcctgc
     4021 caaggcctcg tcaattgagt tatcaacaat ttcccagact agatggtgaa gaccttcttt
     4081 tgaggttgat ccaatgtaca tccctggacg catacgaaca gcctctaagc cctctaaaac
     4141 ttgaatttga ctggcatcat aatcctgtgc ctgcagattt ttgatttctt ctgtcatctt
     4201 attccttttt cttatatgtc taatacttgt cttaaattca cgatactggt aaacaagtgg
     4261 gtatcaagtc ctgcagcttg acctgcttcg atatcaatcg gccgatcacc aatgacaaga
     4321 ccagagctaa tctgatactt ttctcttaaa taaagcatgg attcgggatt tggctttctc
     4381 ttaaagcctg agctagaagt caccacttct gtaaaataag ctgctataga ggttttttct
     4441 aaaatttcca aaacctgatc atttcgatga gagaccaaaa aatgacggcc accttgattt
     4501 gaaatgactt ccaataggtc agaaactcct tcaaataaaa tcgggtgttc aagctctctg
     4561 gcttcatttt ccttgtactt ttctaaaaaa ttctctaaat tgggagcgaa tgtctcaatc
     4621 gcaaaagaag tagaaacctt taaagcttga tagacactgt catggtcttg tgtgatacca
     4681 tacagtgcca atgtttcaac aaatgcagct gttgaagttt cataattatc cagtaaagtt
     4741 ccacctaaat cccagatgta atcgtgatat ttcataccct tcattatagc atttttttat
     4801 gaaaaaagcg atgatttccc tgagttttcc acataaaaaa cgagagaata actcccgttt
     4861 tactgatttt taccaaagac atctcgatag agcattcctg ttcgtaaact ctctgcgtcc
     4921 cctcctagtt gctccaccaa ctcgtaggca aaggcaaggg ctgttgaagg accccgactg
     4981 gttgtcaact gaccatctac cactactgtt tccttgacgt agtgaccatc aaggatttgc
     5041 tcttgaacgc cgtcataaca agtgtatcgc ttatttttca atatctctgc ttgattgagg
     5101 gcaattggtg ccgcacaaat ggctgctagt ttcttccctt cttgctcgaa gctttgcaat
     5161 tcttgaatca aggtctgatt atcacgtaaa tgtgcagaac caggcatacc tccaggaaga
     5221 acaatcatat catagtctga taaatttcca tcaaagacat gatctgctct tacttggatt
     5281 gcatgcgaac ccgttacttg ctcttcaaaa ccaaccatat cacatgtgat attggctcga
     5341 cgcaagacat ctacaactgt caaggcttca atttcttcaa agccctgagc taacataact
     5401 gctactttta ccatgatttt ctccttattt aatttgtttt aatacaacct ttttccgttt
     5461 gaatgggact tttccgctct tttcttcagc tagattagtc tggtaactca tcgataaaag
     5521 caaaccaaca ccaatcagat tactgataat agctgatccc ccttgcgaaa tgaaaggcaa
     5581 gggaatcccc gtcaaaggaa gtagtccagt cacagcaccg atattctcaa agatgtggaa
     5641 gagcaacatc ataatcaaac ctgtggaaat ataagtgtag aactggttat ttgatttaag
     5701 agtaatcttc aacatacggt aaatcaacat gagatagagg gcaataacca ggacagagcc
     5761 aataaagcca aaatcttctg caataaccgt aaaaatcata tctgactctc gaactgggat
     5821 aagcagattc gaagcattaa atccctgacc aaataagcca ccactcccaa tggcaatctg
     5881 cccttgagcc tgctggtaag tcgttgtttg ggcaaactca aagggattga gccaagccaa
     5941 aatccgattg atttggtagg tcggcattcc aatctggtga agaaaagctc gtccgtcctt
     6001 gctaataaag atagctaaga aaccagcaac tcctgttaca gcagtcacaa atactgggat
     6061 aataattttc caagaaaccc ctgataataa aacgattcct gagaaaatgg ctacaaaaac
     6121 caaagccgtc cccaagtcac tttgaagtgc taaaagaact aggactggaa tggtaaagag
     6181 aatcatccag aaaattaaca aaaagtccag cggaaccgtg cgtctccatt ccttatgttt
     6241 ctttgtaaat tggacaatga cacgagccaa catgaggata taagatatct tcataaattc
     6301 tgacggttgg aatagggtaa ttccatttat tgatacccag tttttggcac ccgttgatgc
     6361 aactaatctt ggattataaa atacaatcgg caagatcata agtcccaagc ctaaaatata
     6421 tagaaagggg gtcaccttcc aaagaaattc tgtattaaag agcatgacca caaaaccaat
     6481 cacaagcccc aaggcaatcc aggcgacctg ctgccctaaa atgggcaaaa tattattggg
     6541 ataatcatga ctaacggcta tatagatagc caccacaccg atgaccagta gaaaaaatac
     6601 tggcaagagc aaactgtaat cgactcttga gtcgagagaa cgtttcatat atactaacct
     6661 tatactttca tacaatacta tttatcaaag ttcattaaaa aatctatcaa tagcctcgtc
     6721 aacttcggat cgagagatgg ttttaacagt cgcttcttct gctagagata ctactatttg
     6781 tttgccgtat cgttttccga cgattctcct atccaaaata agagttaagg aacgttggta
     6841 ttcacgtctc atacttcttc ccaaagcctg ttttaaacga ataatggcca ttggcaattg
     6901 ataatcataa aaggcatttt tcccttcttg attcagttct tgattaatct ttttcgtcaa
     6961 gggttcttga ggattttgga aaggaagcct cggtacaact tgaatcacaa aaggatggct
     7021 tgaaaaatca actccctccc agaaacttgc tgcaccaagc aagatttgtt gttcaccttt
     7081 ttcaaagcgt ttctttagct gatgaacatc cccattttta tactgggcca agtggctaac
     7141 tgtaagtaaa tccgatactg ctagaagcat gtctttagcg gtaaagagaa ccaaaatcgg
     7201 ttgctggaaa gcttgaattt ccactagtaa agcagctacc tctctggcat agacttctaa
     7261 ggaggtttct gttaccagag ggaaatcttt gaccatgacc acttcttgtt cctgttttcc
     7321 ccgagattca atcttgacaa atttggcttc aggatagcct aaaaggtctg ccaaagaaac
     7381 cctctgacta atctcaagag tagccgatac tcccaagact tggcaactct caggaagtaa
     7441 agaggacaga agagtacggc atgattttgt agaagaaatc tgaattttct tttgactcgt
     7501 ttcagttact tcaagccagt aatcaccttc agctgtaaaa tagcgaacca gctcatcaaa
     7561 gccttctact tctaattctg aaaaatactg atggagattg tccagagaat ctaagatatt
     7621 tttcctagat ttaccagact gaaattgttc tatcaagtag agacactcaa agcgaatact
     7681 ttctagtatc cgttgttgaa ccctgttttc ttctcctact aaagccttat caattaaatc
     7741 gataatagat tgtatatcgt aggtctcttg aagcagattt tctagagcta acaaaatctt
     7801 ttggacttca tcaataatca gtaaacggtc actgacaaat tcaggattat cttcaagtct
     7861 ggtcacgaga taggcatgat tagtcactaa aagcttgcaa gtctctgccc tttcttgact
     7921 acgtttccaa aaatcttccg tcacaaataa gctctgggat gataaattcc catcatgacg
     7981 aaggtctgct agaaaatgtt ggtaacggta gagttgcccg atttcatcca aatctcctgt
     8041 ctctgtctca gtaagccaga ccaagacttg cattttaaag cgtctaaata agcgattttc
     8101 atcattttcc tgcaaggaat gataaaaggc atccaacttc agataatttt gtggtccctt
     8161 taagctatga atatctgtat ggaacacttc cttgaggcgt ttaccttctt cttccatgat
     8221 ttgattttga agaatctttg tcggaacact aagaacaatt tgtcgctctt tggattgaga
     8281 taaagcgggt aagagatagc cataggtttt cccaatccct gtcggcgctt gaatcagaga
     8341 gacaggttca tctttcaata gcaagccaac ctctttagca aaactttctt gttcctccct
     8401 cacttcaagg ttcaacagag aaatattttt agaaaagtct tgagatagtt ttcgtggctc
     8461 cagagaagct gccgttttct taaaatacag accttgaact tggaccaagt ctggagaact
     8521 caggatagat tggttgcgat aagtttcctc aataaccagg taggactcat ataggagagc
     8581 gtcagccatt tccagcaagc gttccaagag acctttagga agctgggtca tcttttcccg
     8641 taaaaaaaga agtaattctg ctgtagcttg ggcatctgaa agggctgtgt gtgcgtgttt
     8701 aagaggaatt cctaattctc gacacaaaat cggcaagcta tatttttcca gttcagggaa
     8761 aaagacctgg gccaattcga ccgtatcaac acgagggttt cttagctcat agccttcaaa
     8821 aaataaattt tccgccaaga gattagcatc aaactgaaca ttatgggcta caaaaatccc
     8881 atcctccacc aagtcaaata tttttctggc aacttgcgaa aaatcaggtg cttgcgccag
     8941 acgttggtct gtcaatcctg tcagttcttt gatatgagca tccaagggtt catgtggatt
     9001 gacatccgtc gtatagtgat cgacgatttc tccgtcctca atcacgacaa ttcccacttg
     9061 gataatttta gccttactac ctgtgctagt tgcctctaaa tccaccacaa catagcgatt
     9121 accaatcgtt ttcattataa aaaattatac caaaaaaagg gccatttggc acctgcaaac
     9181 ataggataat tttcaaactc aagaacacta cttttcttaa aaatcccatc gaatagagca
     9241 ttctagcctg ctgatttttg taaaatagtg aagaaatacg aaaaattgag agaagaaatg
     9301 tttgcatctt ccttctctca acgaatcatg tattttatct aaccatgtca ggatcgtagt
     9361 cataaaatcc tgtatcaagg aaacggtttt tagggtgaag tttacgaact tcttcatcca
     9421 gcaagaaggc ttgatcatgg ctaaagttgc cctcttgaat caagttacgc gcttggataa
     9481 agagttttgc aatctcaaca aagttctgac caggagtgta gagcccttct agtttccagc
     9541 gagtaaagcc atgctccacc aattctgtta atttgatcat caaatcaagg tcattgttgg
     9601 caaagatatg ggtcccatga ttatcttcaa aaatggaata gtggctctct ggatcacttg
     9661 gctcagccaa gaagaggtca cgtttatgcg tcttttcatc atcgatatgt gtaaagttat
     9721 agtagttttg caagagtgga cgtttagaat gatggatgac gctagcaccg taaaccaaaa
     9781 cttcagcagg aatttccaaa atctctggca ttttgaaaag ttcagctgat ggaatttcac
     9841 gcgccaaaac agcctcagat gcgccagcct tttgtcccca gaagttaatc tgacgactgc
     9901 tagttaccat ggttgaagca tcgtagatgg tcttaaatga ataaccatcg cggttaacta
     9961 cgtaaaagac gcctgcatcc ccaatcgtaa tatagtctgt cttgatttct tccaagaagt
    10021 ctaagaaagg cttgatacgg tccatcatat cttggtgcat gagagcattg accgcaacga
    10081 tcaattcctt accagcatca tgaaccaact tagcgatttc acgtaattgg tcataactaa
    10141 aggtcgttgg cagacgaagg ccaaaatctt tctcaccgac atagatacgg tctacgccag
    10201 cttcgagtag ttgttcaact tgttcaatac tttcagcagt tgctgtaatg acaatctttt
    10261 ccataagaaa aattatacca catttctcca aaatcatcca tgctttgaaa atgaaaaggg
    10321 actttattct ttttgtaacc tttctgtaat aattctctgc cgaaaaaatg ataaaatagg
    10381 tatgtactgt taaggagaga attatgcccg taagaaaatt acaatcctat gaggtagact
    10441 atcaagaaga attaaaccag cagcttcctc attaccaagc ttatacacct gaagcgcaat
    10501 ctgatgccaa tctcaaggaa atcctatttt ttattaatat cgctgttttt tgtatctgta
    10561 ttgctatctt tagttttatc tttttagcat taaaattatc aactgctctt gcctttgccg
    10621 cagcaatcgg attcagctta cttgttttaa aagttcaacg gtctattatc aaacgaaaac
    10681 gtagaagata aatccaaaat atcgccccag ttggagcgat atttttattt tttcttttta
    10741 gatggtgtct gaatggcaat cttcacttca aagattgttc ccttgggttt attatctttg
    10801 acagtaacag ttccttttag agcatctaca atttgcttgg ctagggataa tcctaaacca
    10861 aaaccacctt tttgccgggt tctagccttg tctactcgat aaaaacggtc aaaaattttc
    10921 tttttatctt ctgtcgaaat accgattcca ttatcagaaa caagtaaata aagattgcga
    10981 tcggtcgccg agataagaaa atcaatttca ccatcctcct cagtatactt gacggcatta
    11041 tcgaaaagaa tggtcatcag ttgtttcaga agaagctgat ctgtgacaat tgttcgatgg
    11101 atacgatttt caaaacggaa gacacgatta ttttccgaag caatcatctc gtagtttgtg
    11161 aaagttgtat taaaaaagct agttggaact tctgcaagct ccggcttaat cccatcatct
    11221 ctccgagcta agttcagcaa gcttgtcgtt aaaaaacgca tatttcggac ttcttccaaa
    11281 ctcgatgcaa tgctttcgct cacatccata atggtagctt ctggcttacg aaaaagggtc
    11341 tctaagcgat tttgcaaaac tgcgagtgga gttcgtaact catgactggc attttccaca
    11401 aaagactgtt gcttctgcat actctcaagc aggggcctaa cactgaccct agctagatag
    11461 agactggcaa gtaaagacaa aatccagaaa ctagccatca cgaccacaat caattgctca
    11521 tgcttttgac tagcctgttc caactgactg gtattaatca agacagcagc atacttgata
    11581 ttggttgaaa ccgaactaat attggtctcc atcaaaatca cacgatagat ttcttcctgc
    11641 ccatagctat taaaaacctg aatctggtag atatgtccta gttctttctt ttctaactta
    11701 atcttatcca agcccaaaaa tcgatttcca gaaagaagtt gagtaaagtc tttatcaaag
    11761 agaatgactt ccgtattgga actgacatta ggttttattt ctactttact agcgtccgcc
    11821 ctagcatttt ctaaatcttt aatctcttct gttgccctat ttatagccag ctgaataact
    11881 gcttgaggat tttcactcag tccatgaagc ttatcgtcca ccgaagtata aagactcgaa
    11941 tgcatgactt gtaaaataat cagagtcatt gtagaaaaaa tcagggtgaa gacaccgaag
    12001 ttgcggataa aataactaaa gtcatccgca taccatgttt ttttaagttt actgaacatc
    12061 ttttaaaaga tacccaacac tacgcaaagt ttgcaaattc tctgcaaaag tggttccctt
    12121 taatttctta cggacttttg aaacatagac ttcgacaacc gaaatcgttg tatcactatc
    12181 aaatccccat agacggtcaa aaatctgcgt cttaggtaaa atcacatttt gattttgaag
    12241 gaaataaact agtaaatcga actctttccc cagcaattcg acaggagtat cttcaacttt
    12301 aacggtattg gttgataaat taaccacgat attcccataa gtcaaggtgt tttcattaaa
    12361 cttccctgaa cgtttgagaa gagcctgaat ccgcatttta agttcttcta ggtagaaagg
    12421 tttggtcaga taatcatccg ctcccagttc aaatccatgt cccttgtcat ccaaactttc
    12481 cttggcagtc ataatcagaa ctggtgtcgt aattcccttt tcacgcaatt cttttaagac
    12541 ttggaaacca tttttttctg gcaacatcaa atccagcaaa atcaagtcat agacaccact
    12601 ctcagcttcg tagagacctt cttctccatc aaatacctgc ataacatccg caaaatcgtc
    12661 taaaaagtca aatactgaat ttgacagacc taggtcatcc tcaaccaata agatttttat
    12721 catgagaaac tcctccttat taaaactatt ataccaaatt tgccttaaaa aaaactcaac
    12781 tctctgcatt ttacatgaga tagctgagtt ttctttttat tttaggctta tttatgcatt
    12841 tccgtattga agaacaactg cttcgactgc agctttttca cggctaatca agtcaacacg
    12901 cgctgcaatt tccttgattc ccataccgat gttacggcta agagcaaggt cagaaagttg
    12961 cggctcaaag aactccttgt attccgccaa gcgttgctga gtcttaaata catgagcagg
    13021 aaggataaca aagctatcaa agctcatatc tcctccaagg gctgccttaa tccaagccca
    13081 gttttcacgc gcccaagacc aagctgtttt ctgagttgct tgatgagcta ggaattggta
    13141 ataccaagca gacaagtcct gtggtttgac cacaaatttg tccttccaag aagtaatcag
    13201 gttttggata ttatccgcat ctgtactgta tgcaagagct gctgccaact ggcgtttaaa
    13261 gacagcatct gttgcgtgag tataagtatc aagataaagt gctaacaagt ctttagtctc
    13321 atgatgtttc atctcattaa tcagaacttg tgagcgaata gctgctggga gtcctgcaag
    13381 attctccttg tgtgttgcga agatttggct agcgacttga ctagcttctg catcatttga
    13441 gcgaatcatc atcgaaacag ccagctgacg aaccaattca tcctcatctg attctccgtc
    13501 tttagcttca aaaccaagac ggtcatagtt atgacgagcc aatttagcaa ccagtccttt
    13561 gaaggctgtt tcagcatccg ttccttcatc aataaagcgc tcaagggctg aaatcacttg
    13621 agaaacagct gaaaccacca gataagactc ttccttagca agtttatcaa gaactggaag
    13681 caagtctgca taagaaatgt gccctgcctc agccaacaaa cgacgttctt gaacaatttg
    13741 cagtttgctt gtgttatcaa gtgtctctag ctcagcaaga acagcttcta acaagtctcc
    13801 ttgatagtcg gtaatatagt gggcagtatt ttcagtgttg agacgaagag ctccttcatt
    13861 ttcagcaaga agagctgcgt agccagggat ttcgatactt tcagtttcga gtgtatcagg
    13921 caagcctttc cagttgctat tgaggggcac cacccagaga cggttcttgt cttcgttctc
    13981 accgatgaag aattgttttt gtgaaatctt caagacatca ttttcaactt taacagtaag
    14041 aactgggtaa ccaggctgtt ccaaccaaga atccatgaag gctgcgacat cacgtcctga
    14101 cgcttgacca agggcatccc aaaggtcact accaatggtg ttgctgtatt ggtgtttttc
    14161 aaagtaggcg tgcaaacctt tagcaaaatc agcatctcct agccaacggc gaagcatgtg
    14221 catgagacgg cttcctttgg catagacgat agcgccgtca aagagtgtat tgatttcatc
    14281 tggatgttta acttcgacgt ggacagactg aacgccatca gtagcgtcac gttcaagagc
    14341 aagaggtact ccacctgttt ggaaatcttc aaagatattc cagcttggtt cgatggtatc
    14401 cacacagacg tattccatca tattagcgaa actttcattg agccaaaggt catcccacca
    14461 tttcatagtc acgaggttcc caaaccattg gtgagccaat tcatgggcca caacaagggc
    14521 aacttgttga cggctagcaa atgtagagtt ctcatcgaca accaagtaaa cttcacggta
    14581 ggtcacaaga ccccagtttt ccatagcacc agctgagaag tcaggaaggg cgatgtggag
    14641 agattgagga attgggtact taactccata gtaatcttcg taaaactcga tagagcgaac
    14701 agcgatatcc agtgagaaat caagatttga aagtggatgt gctttggttg agtagacacc
    14761 taccagggta ccatttttag ttttagcggt caccccttgc aaatcaccag caacaaaggc
    14821 caacaagtaa gaagacatgc gaggtgttgt ctcaaacttc cagatacctg tttccttacg
    14881 gttttcaaca tcgatttctg gcatgtttga caaggccaat tcaccttctg cttggtcaaa
    14941 gcgaagagag aggtcaaaag ttgctttggc ttcaggctca tccacacatg ggaaagcttc
    15001 gcgcgcaaaa tggctctcga actgagtaga caagacctcc ttcttgactc catcaactgt
    15061 ataataagaa gggtaaatcc ctgtcatgtt gtctgtaatt ttaccagaaa aggcaagaac
    15121 caattcaact tgaccagcct cagccaattc gatatgaagg gcttcattgt catggtcaac
    15181 tgtaaatgga cgagcttgac ctgcaacttc tacagaggtg atttccaagt ctttttggtg
    15241 gagggagatg cggtcactct gtgcttgacc agtgatggtc actttcccag aaaaagtctt
    15301 ggtctcacga ctcaaatcta aaaataaatc ataatgttca ggaacaaatt gcttaataaa
    15361 atgttcaact gcttgcatag ttttctccta ttctaagttt aagagctgct gctcttcttc
    15421 aaacaaactt attatatcat attttgcttg agaaaaaagg attggacagc gatttccaaa
    15481 actttcttcc ttctaatagt ctacagtggg tagaccttgc gaaattcttc taaaacaacc
    15541 ttgctttcag gtgtaaaagt cagccctact tcacccaaac agtctgtgaa aaagtcctca
    15601 tgaacctggc gccaataggc aagtgatttg tctccctcac cttccttaaa ggcatgttgc
    15661 gcagaaactt gattgaagag ttcaacagaa acctttgtaa tttcgacaat gcagacagac
    15721 tgattttgac tatctaaaat gacatcgaag gtccctactt ggggaagtgg ttcgtcttct
    15781 agtacataga ggtcataggc tgatgctgtt gctgtctttt ctcctttaaa caccaaatcc
    15841 gctaaaaggt ctggttcaac tccaaaagcc caagcatcga tttcatctcc gatcaaagga
    15901 ttgatttgct tgtatttatt ccacatttct tgcggtatca tgggtactcc tttgtaattt
    15961 tttactttct tcttttatgt gtttaagatg atctggatgg tcaatctcta aatcaaaaat
    16021 ctctggaata gaactgtagt ggataatgca cttgataccc aactgattca ttttttgtat
    16081 gaaagaagta ttcagatagc ctgctacagc aaaatcaatc ttgttctttc ttgctttatc
    16141 ctgcatatct cttagcatat ctaacattat tggactttcc atatcatgcc attgactgtt
    16201 tctcatagtc gcaaaaacaa aggaagtcaa atcattcatt ccaactacaa tctttgaaat
    16261 gcccgtttcc agtatcctat ccaagtcaaa atacgctgac ggtaattcaa tcatcgttcc
    16321 gactttccca gtaaagccat actgacgcaa tactgtaata gcttgtttta attggtcggc
    16381 atcattgaca aaaggaaaga taagagatag attgggattg gtttgataaa cttctgtaac
    16441 gacatgtgct tcagcctgaa attcatccaa acacgccagt aaacgcctgg ttcctctata
    16501 gccaaacaag ggatgccctt cgtcaaaaaa ctctctagtc cccactaaac aattggcttc
    16561 tgtattcgtt aattcagaaa aacgatacca aacttcttca tctgagtaca gggagcagat
    16621 agtctctaga taatctttta caaattgctg acaacttgct aatatgatgt tttgattaag
    16681 ctctctcaac aaatattccc cacgaatcat gccgacgtgg tgaaatagtt gaggataaat
    16741 tttttcaaga attttttcgc cactaagggc aagttgattt ctcatcattc accttccaat
    16801 tcatgtaaga agtcttgtcc agttctggaa atcctaataa ttcagactta accttcaaga
    16861 ctaatggcga tgcattttct tctgtaatct cttgaatatc catccaaata tatccaagtg
    16921 aatcattcgc accatcagac acagcttccg aagtcgtaac ttgaggtgca ctctcattca
    16981 tttcaacatc atacaaggcc atgacatggt gaaccataaa atttgttaac tcttctctga
    17041 cgaaaacatc gtagattcga ggattagagt agcttctaac agtaaatccc gtctcttcca
    17101 taacttctct agtcagcgtt tccgtcagtc cttcaccaag ttgctgactg cctccaggta
    17161 gatcataccg atgttgataa gggcctctcg ttttttcaat gcagagtaac ttcccatttt
    17221 ctaagcaaac agcgtagact ccaaagtgtt ttttgatttc catccaactc ctcctacttc
    17281 aaagaccagc caccatctat tgtcaagatt tgtccttgca tggcgctcgc ttttccactt
    17341 gctaaaaaaa gactaagctc tgctatttcc tctggctcaa tccagcgctt gattggggtt
    17401 tcactagcca cccagtcagc caaaccacct ggttcaaaat ccgcagcggt catagctgtc
    17461 ttgactgctc ctggagcgat accaaagacc tgaatcccag cttcagcata gtctagagcc
    17521 aactgcttgg tgaagccagc caaggcatgc ttggatgaag tataggcgtg accacctcca
    17581 cctgctaggc tagaagcaat ggaacacata ttgatgatga ttcccttttt attttccagc
    17641 atttgtgtca aataataccg agtcaactca acaggagtca tgtagttaat ttcaaaaatc
    17701 tcttgaattt cctgcgcagt ctgttccaac agtggtttgt aagcatccaa aactccggca
    17761 gtattacaca aaacatccac ctgagggcac cagtcaaaaa taggttccaa gtccaaggtc
    17821 aaatctctct gtaaaaagtg aaaatcaccc tctaagagtg gcttttcacc ttggtcaact
    17881 ccataaactt gatagccctt ctctaaaaag aggcgagctt gagccaatcc gatccctgaa
    17941 ctcactcctg taatgagtac acgtttagtc atgcacttct acccaatccg ttgccaaaac
    18001 atcacaagct gtcgggctcc acatggaaaa accttctcct tctccagaca cgttgattaa
    18061 gaaataaggt gtcacttcaa gtgcaagccc attttgctcg atggtatcaa agagttggac
    18121 atagttttca gcacctcccc aaccagttcg tacatatttt ttcttagcct ttaagccagg
    18181 tagaatttct tcaaatgtca tgtttttctc ctttaatgtc aataattctc cccttcatta
    18241 taacaaaaaa accgctttaa aacggctttt tgactgtgat ttatttacat cttcttctac
    18301 ttacggcaaa ttattccctg cagcaagata aatttcatac cattcttttc ttgttaagct
    18361 aaagtttgcc gcttggctaa cttctctcaa gtgcttagga tttgtggtac ctacaactgc
    18421 ctgcattttt gctggataac gcaatatcca agaaatggca atagttgaag aggttactcc
    18481 atatttaata gctaaacgat caagtacttg atttaaagct tgaaatttct catttccaac
    18541 aaagttccct ttaaaatacc cgaattgcaa gacagaccat gcttgaatga ccacatcgtg
    18601 taatttgcaa tattcaaaaa tgctgccatc tcgcatagct gcttgactat cttccatatt
    18661 aacatgaaaa gctgattcaa atcctggagt aaaagccgca ctcaattgta gctgattaac
    18721 agctaacggc tgcttgacat cttttttaag caactccatc atcataggat tttgattaga
    18781 aactccaaaa tctcgaactt taccttgttt ataaaggaga tcaaaggctt ctgctacttg
    18841 gtcagattcc atcaaagcat ctggtcgatg aaggagcaag ctatctagat gatcaatctt
    18901 caatctttgc aaaataccgt ctactgattt tataatatag tccttagaaa aatcaaaata
    18961 ggtaaattct tcaatgcgaa tgccacattt ggactgaatc cacatctttt ctcttaaatc
    19021 tggacgattt tttaggacaa gacctaacag ttcttcacaa cgaccacgac cataaatatc
    19081 agccaagtcg aaggcattga ttccaacaga aagtgctgtt tctacaagct cttcaacttc
    19141 ttttacagac ttatctttta ttctcatcat tccgagaaca atttctgata attctttgtc
    19201 atcttgacca agagttatgt atctcatcaa atttttctcc tttaatttct aacattcttc
    19261 ccttcattat aacaaaaaac cgctttgcaa cggctttttg actatacttc actccatttt
    19321 atcttcttaa acccacggaa caagacaaag attccaataa agaggacagc taaaggaata
    19381 acttttgtaa ggaaaacatt tgaaattccc atccactcat aataacggag cagagaaccc
    19441 accacaagat gggcaataat catactgaca aatggacgaa agaccgcttc tttccaattc
    19501 caaataccga taactagcga aatcgtaaag acagacaaac tatcccaggg agccggaata
    19561 taaaaggctc cttcttgtat gaagcttgcc attcctacat atcctaaaac aactagaaga
    19621 actatagtcc caacaacaat gtaagtgcca attttcattt taggagaatc ttggactaaa
    19681 cttcttcgta aaattgtggc cacaagtcca aatccaatca gaaaaataag aagttgccct
    19741 aaaaatgtga gcaaattgac tgttaagaga ggacctttag aaaaatcact tagtagttga
    19801 taataacgta ataccgccag gacaagaatt ggcgtcaaaa gggactcttt gatagaactg
    19861 cgaggtgctc ccttgagaat ctctttcatt atttttttag gattcttacc tagataatcc
    19921 tctgcactca tgccatctcg ttctgcttct gagaaatcta gcatcatcaa atagatctgc
    19981 tctctgagat agtcttcatc atagagaaat ccagcaagat taaaactttc ccacaactcc
    20041 tcaaaatact tttgattctc ctcagaaaac tcatgtagca aagcgcttgt ttcttcgtaa
    20101 tacttcattt tcttcatggt ttaaccccca ttcttaatcc cttctacttt ttgactcaaa
    20161 tcgtcccatt gttgccaaaa gactgagaca cgctcttctc cttctttcat taatgaaaaa
    20221 tacttccgat ctggaccatc tggcgacggg cgcatgtcgc ctcttatcca ttgatttttt
    20281 tctaactttt gcaacaaagg ataaatagtt cctggaacga tagtatcaaa tccagcctct
    20341 cgcaaagtct gaaccaactc ataaccatac cgctcttttt gaccaatcat atccaagaca
    20401 caaccttcaa gaacaccttt taatagctga gtttctttca tcacttctcc cttctaatct
    20461 attttgtaat acctactagt aacttcacct atagtatatc acttctacac tagtttgtaa
    20521 agcataatag ttaatactct tcgaaaatct cttcaaacca cgtcagcgtc gccctaccgt
    20581 atgtatggtt actgacttcg tcagtttcat ctacaacctc aaaacagtgt tttgagcaac
    20641 ctgcggctag cttcctagtt tgctctttga ttttcattga gtataaataa aaaaacagaa
    20701 ctagtctgaa ctagtcctgt ctacttttac ccaatcacac ttccatttgg tacagctgga
    20761 tcaactgtga gaagggttaa tttgccatca tgttcagctg atagaatcat accctggctg
    20821 acatattttt tcatcatttt acgtggtttg aggttagcaa cgatttgaac tttcttgccg
    20881 accaattctt gttcatttgg atagtatttt gcaattcctg aaagaatctg acgatcttct
    20941 ccatcaccag catccaagcg gaattgaagc aacttatctg aaccttctac tttagacact
    21001 tctttgactt ctgcgacacg gatttcaacc ttgtcaaagt cttcaaactt gatttcatcc
    21061 ttgtttagtt tgagctcaac ttcgtccgga ttccattctt tttcgactgc tggtttattg
    21121 ccttccattt gttccttgat ataggcgatt tcttcttcca tatttagacg tggaaagata
    21181 ggtgttcctt tggcaactac agtcacatct gctgggaagt cagccaaact caagttttca
    21241 agactagaaa cttcttccaa accaagttga gtcaaaactg cacgactagt ttccatcata
    21301 aatggttcaa tcaagtgagc aactacacga atgctggctg ccaagtggct catgacactt
    21361 gccaattggt cacgaagagc ttcatccttg gccaagaccc atggtgcggt ctcatcgatg
    21421 tatttattgg tacgagagat cagagtccag actgcttcaa gcgcacgtgg atagtcaact
    21481 gcttccatgt gtgtatggaa gtctgcgatt gattgttctg caacctcagc aagaacatga
    21541 tcaaattcag tcacaccttc tacataggca gggatttgtc catcaaagta cttattaatc
    21601 atggaaaccg tacggttaag gaggttccca aggtcattag ccaattcata gttgatacgg
    21661 ccgacatagt cttcaggagt aaaggttccg tctgaaccaa ctggaaggtt acgcatgagg
    21721 tagtaacgaa gtggatctag tccataacgc tctaccaaca tttcagggta aacgacattc
    21781 ccttttgact tagacatttt tccgtctttc atgacaaacc aaccatgggc aatcaaacga
    21841 tcaggtaatt taacatccaa catcataaga aggattggcc agtagataga gtggaagcga
    21901 aggatatctt ttcctaccat atggaagact gttccattcc agaacttgtc aaagttacca
    21961 tgttcgtctt gagcgtagcc aagagctgtc gcatagttaa gaagggcatc aatccaaacg
    22021 tagacaacgt gttttggatt tgatgggaca ggcactcccc atgtaaaggt tgtacgagat
    22081 accgccaaat cttccaagcc tggctcgatg aagttgcgta gcatttcatt aaggcgacca
    22141 tctggcgtga taaattcagg atgagctttg aaaaattcga ccaaacggtc ttggtatttg
    22201 ctaaggcgaa ggaagtatga ttcttcagaa acccattcaa cctcatgacc tgatggagca
    22261 ataccaccag tcacatttcc agcttcatca cggaaaactt ctgccagctg gctttctgta
    22321 aagaattctt cgtctgatac tgaataccaa ccagagtatt cacccaagta gatatcatct
    22381 tgagcaagta agcgttcaaa gacctgtgcg acaacttttt catggtagtc atcggttgta
    22441 cggataaatt tatcgtatga gatatctagt aattgccaga gttctttaac tccaaccgcc
    22501 attccatcaa cataggcttg aggtgtaata ccagcttctt ccgctttctg ctggattttc
    22561 tgaccatgtt catcaagacc tgtcagataa aatacatcgt agcccatcag gcgtttgtaa
    22621 cgtgctagga catcacatgc gatagttgtg taggcagaac cgatatgaag tttcccagat
    22681 ggatagtaaa tcggcgttgt aatataaaaa tttttttcag acataatttt tcctttccag
    22741 gcaaatgaaa cctgtttttc taacacttca ttatatcaca tttttaatga atttcgatag
    22801 ggaaatccat acaaaaacaa gatagacgag tgtccatctt gttgatctca ttcataacga
    22861 agggcttcaa ttggatcaag tttcgatgcc ttgttggctg gcaagactcc aaaaatcata
    22921 ccaacactag ccgaaactgc aagactaaat agggcaactg ggattgatac tccaacttct
    22981 ataccttcta ttaaaccttg cagtaacaaa cctgctaagg cagttaaacc acttgcaatt
    23041 gtcaagccaa ttaagccacc taacaaggtc aaaatcatgg attcaatcaa aaactgaatt
    23101 aaaatattgg cacgtgttgc acccaaagcc ttacgaagac caatctcacg agtgcgctct
    23161 gtcaccgaaa ccagcatgat gttcatgaca ccagttcctc caacaaagag agaaatccct
    23221 gcgatggaac taataatcgt cgtcataaaa ctaaacgatt gttgaatttc tgcaaataca
    23281 acggactcat ctgccacctg gtattctccc tgttgtaagc ctgcaagctc tgtcattttt
    23341 cgtgccagtt ctggacccag agttggggtt aaactggtat cattcactcg aaagacaata
    23401 ttagctattt catctacatt aaaattcgca gcaagggaga tattggtagt aataggcaag
    23461 ccaccaaacc catatatttt tgatctttta gcctccggac tagtataaac cccaatgacc
    23521 cggtaactaa atccattgac ttctacaacc ttgttaatag cctcttgagg agattcaaat
    23581 aaactaatgg acaattcctc atctagcaaa atgacacttg caaactcttt gaaatcttgc
    23641 tctctcagac tacgacctgc aataatttca ttcttaacag cgtccatgta agttctgttt
    23701 ccacctgtca aattagcatt ctcaaccttt ttatcttgat aggtcaagat ggcattcgtt
    23761 gaattggtta catagtaact atccactccc ttcagtttag ctgcctcttg aacccaggat
    23821 tcttgcggtt ttggcggttc aacaggaact tcctcttcct ttccagaaac cgtaaaagct
    23881 gattgtttct gagtaaaaga cccatcttta ctttttttag gagagaaaaa gacgctaata
    23941 tttttctgag atttagtcat atctttattg acttgacgag atagggaatc acccaaagcc
    24001 ataatcacaa caactgatga aacaccgata ataatcccaa tcatagtaag caaagaacgc
    24061 atcttgtgag ccatgataga tgaaaaggca aatttcagat tctgcatctt agttttcctc
    24121 ctttcctaac tgagcactgt cagacgaaat gaccccatcc cgaatgacaa tctgacgttt
    24181 ggcataggca gcaatctcag gctcatgcgt taccatgata atggtttttc cttctttatt
    24241 caaatcaacc aataattgca taatttggtt acctgttttg gtatccaagg ctcctgtcgg
    24301 ttcatccgct aggataatag aaggattgtt taccaaggca cgcgcaatgg ctacacgttg
    24361 cttttgacca ccagataatt ctgaaggtaa atggtgacta cgttctgtca attcaacctt
    24421 gtctaaatat tcctcagcca acttgcgacg ttttgaagac gaaactcctg cgtaaatcaa
    24481 gggcaattct acattttgca gagcattgag cttcgataga agaaagaact gctgaaagac
    24541 aaaaccgatt tgttggttac ggaccttagc cagttgtttt tcaccaagcc cagccacttc
    24601 ttgaccttca agataatatt ctccactggt tggtgtatcc aacatgccaa tcgtattcat
    24661 cagagtggac ttaccagacc cagatggtcc catgatggct acaaattcac cctcattcac
    24721 ttctagattg atatttttga gaacctgcaa ttcttggtca ccattacggt agcttctgaa
    24781 gatatttttt agactaatta gttgcttcat cagccttcac ctcttttcct tcttccaagg
    24841 aagatgttgg attactgatg accttagcac cgttcgttaa accagaagtg atttcttgat
    24901 tttctgcgtc agcatttccc aatgaaacct caactttttt agccttttgt tgttcatcca
    24961 caatccagac ataattttta ctatcatcca ttactagact gctaacagga acaagaatag
    25021 ccttagtttt gcttttaacc tcaatgttga cagaaaaacc ttgtttcaaa tcaccaacct
    25081 cgcctgtcac atcaatagta taagggtatt tagaacctgt attattcccg gctgctggac
    25141 tagctgcttc accattgttt ttaggatagt cagaaatata gcttaatttc ccagtccatt
    25201 ttttatcagg atacacttta gaagtaaagc ttacttcttg acctacagaa aggttggcta
    25261 gattgtactc agacaattct cccttgactt gtaaattttc attgctgaca atatgaacca
    25321 taacttggct cgcccctgtt ggagatttag aaacattgct attgacttcg actacagttc
    25381 cctctagggt actgagaaca gttgttgcat ccaattgact ttgagcctta cttaattgcg
    25441 ccgcagcatc tgcacgcgca tcacgggcat cacccaattg agcgtcaata gaagcaacag
    25501 aatttccagc cactggagtt gggctttgca ccgttgcatc ttctcctcct actggcgctg
    25561 gtaactgtgg agccggagct gaagcggctt catttcgtgc ttgattgagt tcattgatat
    25621 gacgatctgc cttagctact gctcgactag ctgaatcata ggccgcctgc gcttctgaac
    25681 tactgtactt gactaaagcc tgcccttcgc tgaccttatc gcccacagaa acaaggattt
    25741 catctaaatc acccttacta gcatcaaaat aaacatattg ttcatttttt gctgttactg
    25801 tccctgacaa taaaacagag gatgccacgc ttccttcctt ggcaacaaca agatgagtag
    25861 gctcatcttt tagagcagtc tgagaaggtt gtctaaagag taaaatcccc ccggcaccca
    25921 atacaactac actcgcagca ccgattgctg catacagttg ccacttttta gctttaccat
    25981 tctttttctt cataatgaaa ctccttttct tttttacaat actttgctat tataccaaat
    26041 ttccctccag caaacaatgc agttcagatg gaaataatgg cagttcagga ttaaacaatc
    26101 gttcggaatt ttgcttttct attgtactag atatataata cactatcttg acttatttgg
    26161 caagcttttt tgcaattttt tgtgcgtagc agatttttgc aatcaaatca aaaaaagaat
    26221 aaaatataac tatcaaaaaa gacactctac tatttaaaag attacaaagg agttttcaat
    26281 gagagaatat gatatcattg ctatcggtgg aggtagcgga ggaatcgcta ccatgaaccg
    26341 tgctggtgaa catggagcca aagcagccgt tattgaggaa aagaaattag gtggaacctg
    26401 tgtcaacgtc ggttgtgttc ctaaaaaaat catgtggtac ggggcgcaaa tcgctgagac
    26461 tttccatcaa tttggagaag actacggctt taagactact gatcttaact ttaactttgc
    26521 aaccctacgt cgcaatcgtg aagcctacat tgatcgcgct cgttcttctt atgatggtag
    26581 ttttaaacgc aacggtgtag acttgattga aggtcatgct gaatttgtag attctcatac
    26641 tgtaagcgta aatggtgaac tgattcgtgc taaacatatc gtgattgcta caggtgccca
    26701 tccaagtatt cctaatattc ctggtgctga gctaggtggc tcttctgatg atgtatttgc
    26761 ctgggaagaa cttccagagt caattgccat tctaggcgct ggttatatcg ccgttgaatt
    26821 agctggcgta ctccacactt ttggtgtcaa gacagatctc tttgttcgcc gcgatcgtcc
    26881 tttacgtggt tttgattcct acatcgttga aggtttggtc aaggaaatgg aaagaacaaa
    26941 cttaccactt cacactcaca aagtccctgt caagttagaa aaaactactg acggcattac
    27001 cattcatttc gaagatggta ctagtcacac agctagccaa gttatctggg ctacaggtcg
    27061 ccgtccaaac gttaagggct tgcaacttga aaaagctgga gtgactctga acgaacgtgg
    27121 ctttatccaa gtggatgaat accaaaatac tgttgttgag ggaatctatg ctctaggtga
    27181 tgtaacgggc gagaaagaac tgactccagt tgcaatcaag gccggacgta ccctatctga
    27241 acgtctcttt aacggaaaaa ctactgcaaa aatggattac tcaactattc caactgttgt
    27301 cttttcacac cctgctatcg gaactgttgg tttgacagaa gagcaagcta ttaaagaata
    27361 cggtcaagac caaatcaagg tttataaatc aagctttgca tctatgtact ctgcttgcac
    27421 tcgcaaccgt caagaatccc gtttcaaact cataacagct ggttcagaag aaaaagttgt
    27481 cggacttcat ggaattggct acggcgttga tgaaatgatt cagggatttg ccgttgctat
    27541 caaaatggga gcaaccaagg ctgactttga tgcaactgtg gcaattcacc caactgcatc
    27601 tgaagaattt gtaaccatgc gttaatcgaa acaaaagaag ctgatataaa tatgtctgct
    27661 tcttttttaa tgattttcga atcaacaaaa aaattatcca acttgactag tcacgaaaat
    27721 cggctgttac agtttttgtt accttgtttt taaaaaatgg ttgacatcga ctcctatatg
    27781 agtataatag ttactataca ttagaaaaga ggttaactat tttgaaaaaa gctcacgttt
    27841 atgctatccc tgctattggg gctgctctca ttgctgtttt ggcacaaatc agtcttccaa
    27901 ttggacctgt tcccttcact ctgcaaaact ttgcaatcgg cttgattgct actgtcttta
    27961 gaccgagaga ggctgtactt tctgctggac tctatcttct tctaggtgct atcggtcttc
    28021 ctgtctttgc aggaggtgga gctggttttc aggctttagt tggccctact gcaggctatc
    28081 tttggtttta tctcgtttac tctggactta cttcctctct aaccaacagc aagagtggtg
    28141 ttgttaagat ttttcttgca aacctcttgg gtgatgccct tgtctttgtc ggcgggattc
    28201 tcagcttgca tttcctagct ggaatggcat ttgaaaaagc tcttgttgtg ggggttcttc
    28261 cctttatcat tccagacctt ggcaaacttc tggctattag ttttattagc cgtcccctac
    28321 ttcaacgcct taaaaatcag gcttacttta ctaactaaaa aaggataccg agttatcatg
    28381 actcaatatc ctttttttta ttttgaaaac ttatactcaa tgaaaatcaa agagcaaact
    28441 aggaagctag ccgcaggctg ctcaaaacac tgttttgagg ttgtagatga aactgacgaa
    28501 gtcagtaacc atacggcaag gcaaagctga tgcggtttga agagattttc gaagagtatt
    28561 agttgccttt aaaggcatcc accatcgttt gaaattcttc atttgagaga gtaatccctt
    28621 tgcccatttt agtatggtct ggactccaag cacgaatatc aaactttgca ggggcaccat
    28681 taaagctcac acggttaatt tccttggtcc aacctttttc gttttcagaa agagtcaaca
    28741 agtgctcttc gatttcaaat gtaaattctg ccattttctt ctcctttttt agtttcatta
    28801 gtttattcgt aaaatcttgt agattttagg aaaattttat ataatattga tataaaagaa
    28861 gggaggccaa tatgagacat aaattccagc aagttctaga taaaatacat gattttttaa
    28921 atggacatga ccaacctgac cagactgaaa ccaactccct tacagccact attgaagagg
    28981 ctatccagaa acaaaccgct gttcacctta tcttgtctga gacaagcttt acaggtgata
    29041 tcatcaaata tgatcagcaa ggccagcaaa ttatcgtgaa aaattttgcc aaaaatgtga
    29101 gccggattat ccgtataagc gatattcaac gcctgcgatt tgtcccctca actgtccaaa
    29161 cagcccaaaa aaatagattt aagaaagagt gagatgtagt tgcttcatcc cactcttttt
    29221 tcttagcgaa tttgttcaaa atgtaaatga actgcgatat gatctccata accacttctt
    29281 tccaagtcac gttgtaaacg ataggaaatg tagtgttctg caatggtaat gtaacctgcg
    29341 cccaataaac gatgttcaac catagattga atcatactga tagtcgcacg ttccaccttg
    29401 gcttcttgta aatccaaaac taccttctta gtgacttgag caagattttg acgcaaatca
    29461 tctgtcaaaa cataaacagt ttgggctgcc ttcaagatgg cttggtaaat cttatctgga
    29521 ttaaattcag caatttcgcc attacgtttg attacttgca taggtttctc ctttattctt
    29581 tgttttcttt gatttctgcc agcatttttt cttcttctac tgtcagttga taatgttcaa
    29641 gtaaatccgg tctgcgctcg taggttttct ttaaactctc gtacaatcgc cactgacgaa
    29701 tcttttcatg gtggccactc atcaatacat ctggcacgac catgcctcga taatcatagg
    29761 gacgtgtgta ctgaggatat tctaaaagac ctgaagaaaa actatcatct tggtggctag
    29821 actccttgcc aatcacttct ggaatcaggc gaactgtagc atcaatcatg gtcatagctg
    29881 ccaattctcc accagtgagg acatagtcgc ctagggaaat ctcatctgtt accaaggtct
    29941 taatgcgctc atcataaccc tcatagtgcc cacagataaa gattagctct tcctcttgag
    30001 ccaaatcttc agcataagcc tgatcaaact gctttccagc aggatcgagg agaataacgc
    30061 gcggattttt cttttcaata gcatcaaagg aatcgaaaat aggttgtgct ctgagcaaca
    30121 tgccctgacc gcctccgtag ggctcatcat ctacatgacg ggccttttca gcattttctc
    30181 gaaaattatg atactggata tccaagagcc ctttttctcg agcctttcca acgattgagt
    30241 gctccagtgg agaaaacatc tctggaaaga gggttaaaat atcaatcttc atcgtctaac
    30301 ccttctaaga tttccacatc gacccgttta tttggaatat caacattgag aaccactggt
    30361 gggatataag gtaaaagcaa atcacgtttg ccttttcgtt tgaccaccca gacatcatta
    30421 gcacctggtt gcaggatttc cttgatggtt ccaaccaagc tatcaccctc atagacttcc
    30481 aaaccgataa tctcgtgata gtaaaattca ccatcgtcta ggtcattcaa atcttcctca
    30541 gcgaccttga gactgtatcc cttgtacttt tcgatagtat tgatatggta catatctttg
    30601 aatttaataa tgtcaaagtt cttctgttta cggtggctag cgatggtcac tgtttggaca
    30661 aactgatctt tttcatcaaa caaagtcagc tcagctcctt ttttaaaccg ttcttctgca
    30721 aaatccgtca cagacaatac tcgcatctca ccctgtaatc cctgcgtatt aacgattttc
    30781 ccaacattaa agtagttcat cttgtctcct gtaatctcct ttttccatct tattctgaca
    30841 attctcgaat aatagccgca attttttccg attctgacca ttgtaaataa tggtgattcc
    30901 ttcctaaaat gagtttagta ttggaagtcc aatattctga ttctctgtac tctttttctc
    30961 tataagtctg acaaaaaata aatacaggga catgagattc tatcgacaaa ttctcaaaat
    31021 cttcctcagt aatctctcca gatatctgaa attctggatc ttgattttcc aactctaagc
    31081 ctttttcttg cattaattcc cagatttttt tattcgtttc aggactaaat gttgcttgag
    31141 ttaagttctt aaaataaagt tcaggaccac actcgtcaat cagcctcatc tgctcttcca
    31201 tttctggata aggattttct gaaaaatcag caaacatgac ttttttagtt gtcggttcaa
    31261 ttgctactaa agtctgacac ttaattggtt tctcgagtaa tttgcaagct aaaattccac
    31321 tccaactatg tgcacaaagt atatattcag aaattcctaa ttcttcaagt acttcataaa
    31381 ccgcatctgc aagattatct agattttttc cagcttggtc atgaatcgga ctcctacctg
    31441 tgttcggaaa atcaattgtc aaataaccaa ttgtaggagg aggtttttca agtataagtg
    31501 aaaaattttc ataacttggt agcaaacctg ctccgtttag acaaactagc actttctttt
    31561 gctttttata agtaacagag aggctaccaa tttctgtaga tacttcaaac ctcttcataa
    31621 agaaatccac tcattctata taatgaatta ttaaaaatcc ttatccttta ttttatcacg
    31681 ttccaaagat tttctcaagt tggaggaagg ggacaatatc tctactttcc cttcaagaat
    31741 ccttccaaat catgtttatg ttggtaatta acggctgcgg ttttgtcttt ctcaaagatg
    31801 gttctagtta ggtcaatatg cttgatagca gcaatagcga cggtgtagtg aatgatatta
    31861 gccagttcta tggcaggttc ctcgttcgaa tcctatccct tcttttcgac cagagcgcct
    31921 attcaaaacc tcggctactt ctccgacttc ctccactaac ttcataaaga gaccttcatc
    31981 agtccgagac tgctgttaat gttcgagtaa gtagtcttgg aattgcctaa acgttcaatc
    32041 ttttatagta tattgaaact agaatagtac acctttactt ctaaaacatt gttagaaatc
    32101 gatttgactg tcctgatcga tttgtcctgt tattatttca ttttactata tcttctattc
    32161 cacacaaaaa agcgagacat ccgtcccgcc cttcttattt ttcgtcaata acgattctta
    32221 cttttttgta ttcagttggg acagagtaga caatcgttct tatcgcagaa atagtgcgac
    32281 ccttacgacc gattacacga cccacatcgc tttgatcaag attcaaatga tattccaaaa
    32341 attctggtgt atcctcaatc ttgatagtta aggcatctgg ttgtgaaatt aagggtttca
    32401 caatcgcaat aatgagattt tcaatcgtat ccatctgtca acctacttta aacttatttt
    32461 gagaatttag aatcgtggaa ttttttcaat acgccttctt ttgaaaggat gttacgtact
    32521 gtgtctgaag gttgagctcc attagccaac catgcaagaa cgcggtcttc tttcaaagtt
    32581 acttggtttt cagcaacaag tgggttgtaa gttccaactg tttcgatgaa acgtccgtca
    32641 cgtggtgaac gtgaatctgc tacgttgata cggtagaaag gttttttctt agaacccata
    32701 cgagtcaaac ggattttaac tgccattttt aaagtctcat ttctttaatt ttttatttcg
    32761 gtgaaatagc tgagctattt agcacatgtt ctattatagc agatttctgg caggtgtcaa
    32821 gaaaaaaact tgacagacta taaatttctt aaagcattta gaaatttgtt agaataggaa
    32881 ataaatgttt gaaagatgct atccgtgaat actattttag aaaaatttta taaagaacac
    32941 caagtcaaac ccttcatatc gcctgaacga gatttggata cttggcttct aagtcccaaa
    33001 cccgttccca agcgaaatat ggacttatta gcagatgatt cactagcagg agatatcatt
    33061 ttactatgga gaatccagtt tggtactttt accactgaaa catgatttta aaaactccca
    33121 ttcgaatatg attcaaaatt cgcttagaat caatgttttc ccactttttc aaaaaataaa
    33181 ttttcatcta atttaaataa ctttcaatta agtgtgaatt ttgcttaaaa tcattaaaaa
    33241 acaccccatg gtgtgaacca tgaagtgttg taaatgctgt gttgtagcta gttcttagcg
    33301 tttagagaac tggctagctt tacgagcttt cttaagatct ggttccctaa atactttgag
    33361 tacacttatg gcattgatgc cccaaaacat ctaaaaactc tggtagaaaa agggtatgct
    33421 cttgtcgaaa cttcttttga ctcacttgac catctaaata ataccatgaa aaagaatatc
    33481 ctgaagaaga agaagggagt tactggactt tctaaaatga aatcttgcga cctggatcaa
    33541 gcccttcatg agcatttttc agaagaagaa ttagctggtc actttcatgt ccttctatgg
    33601 acttttttac aatggcattg ctatcacacc caatacctat ctaagcgcct ggttcgtaaa
    33661 ctttattgca gctcttcctc taaatttcct aattgttgaa ccaattgccc gttttatact
    33721 aagttctttt cagaaaccat ttactgggga agaagttgaa gattttcaag atgatgatga
    33781 aatcccaact attatctaag ccagttctgt aaactactaa tatttgaaat ccacttcctt
    33841 ttagggtaca atggttataa atgaattttt gagaggatca gaatgaaaaa actagcaacc
    33901 cttcttttac tgtctactgt agccctagct gggtgtagca gcgtccaacg cagtctgcgt
    33961 ggtgatgatt atgttgattc cagtcttgct gctgaagaaa gttccaaagt agctgcccaa
    34021 tctgccaagg agttaaacga tgctttaaca aacgaaaacg ccaatttccc acaactatct
    34081 aaggaagttg ctgaagatga agccgaagtg attctccaca caagccaagg tgatattcgc
    34141 attaaactct tccctaaact cgctcctcta gcggttgaaa atttcctcac tcacgccaaa
    34201 gaaggctact ataacggtat taccttccac cgtgtcatcg atggctttat ggtccaaact
    34261 ggagatccaa aagggaacgg tacaggtggt cagtccatct ggcatgacaa ggataagact
    34321 aaagacaaag gaactggttt caagaacgag attactcctt atttgtataa catccgtggt
    34381 gctcttgcta tggctaatac tggtcaacca aacaccaatg gcagccagtt cttcatcaac
    34441 caaaactcta cagatacctc ttctaaactc cctacaagca agtatccaca gaaaattatc
    34501 gaagcctaca aagaaggtgg aaaccctagt ctagatggca aacacccagt ctttggtcaa
    34561 gtgattgacg gtatggatgt tgtggataag attgctaagg ccgaaaaaga tgaaaaagac
    34621 aagccaacta ctgctatcac aatcgacagc atcgaagtgg tgaaagacta cgattttaaa
    34681 tcttaaaaac caaaaaaata cagtatccac attcggtact gtatttcttt tactctcatt
    34741 cttaagttaa attattaaaa tcccatattt ggtctatcca gccttcataa aagtctggct
    34801 cgtggcagac cataaggata gatcccctat attctttgag agcgcgtttg agctcatcct
    34861 ttgcatccac atccaaatgg ttggtcggct cgtccagcac taaaacgttg ttttcacgat
    34921 tcatcaagag acagaaacga accttggctt gctctccccc tgataatact tgaatctggc
    34981 tttcaatatg tttggttgtc aaaccacaac gggcaagggc tgcacggact tctgcttgat
    35041 taagggcagg aaaggcattc cagacagctt caagaggagt ttggcgatta ccgccttcta
    35101 cttcctgctc aaaataacca agttctaaat aatctccacg ctccacttcc ccagcgattg
    35161 gcgagataat gcctaagaga ctcttcaaga gagttgtttt tccaatacca ttagcaccaa
    35221 taatcgcaac cttttgattg cgttcgaagg taagatttaa aggcttagta agaggacggt
    35281 cgtaaccaat ttgcaagttc ttggcttgga agataaagcg ccctggtgta cgagctggtt
    35341 tgaaatcaaa ggatggtttt ggtttctcac tttggagttc gataatatcc atcttatcca
    35401 atttcttttg acgagacata gccatattac gagttgcaac acgggcttta ttacgagcca
    35461 caaagtcctt gaggtctgca atctctttct gctggcgttc gtaggctgcc tctagctgag
    35521 atttcttcat agcataaact tcttggaact ggtagtagtc accagagtaa cgcgtcagct
    35581 gttgattttc cacatgatag acaatattaa taacgtcatt gaggaatgga atatcgtgcg
    35641 aaatgagaac aaaggcattc tcatagtttt ggagatagcg cttgagccaa tcaatatgct
    35701 cagcatccaa gtagttggtc ggctcgtcca acagcaagat atcaggcttt tcaaggagaa
    35761 gttttgccaa aagcaccttg gttctttgcc cacctgacaa agaagttaca tccgtatcca
    35821 tgccaaagtc cataacacca agagcacgcg ctacttcgtc aatcttagca tccaaggtat
    35881 agaaatcacg actctccaga cggtcttgaa gttctcctac ttcttccatg agagcatcaa
    35941 catccgcgcc gtcttcagcc attttcatat agaggtcatt gatacgagct tcagctttaa
    36001 aaagctcatc aaaagccgta cggagaacat cacgcaccga ctgtctttca gcaaggacag
    36061 agtgctgatc caagtaacca gccgtcacat atttggacca ctcaaccttt ccttcatctg
    36121 gcagcatttt accagtcacg atactcataa aggttgattt tccttcacca ttggcaccga
    36181 ccaggccgat atgttctccc ttgaggagac ggaaggacac atcttcaaaa attgcacggt
    36241 caccaaaacc gtgactcaga tttttaactt ctaaaatact cattttaatt ccttatcttg
    36301 tttttatgta atcgtttata aaggagccaa gccagatagc cacccaaagt gttggtccac
    36361 aaatcatcaa tctcaaagac gcgattgaaa tcaaagaaaa agtccaagat taattgcgta
    36421 cactcgattc caagactcac aagaaaacta aaaagaagga ccttttttgt tttccgcaaa
    36481 tttggaaata gataaaggag ttggaaaatc agaggaaaaa acaagaagac attgaggaca
    36541 ttttgtaaaa aaatccaaca taattgtcca atgtcactca cttcgcccag tttccagaga
    36601 gaattgaaag gagtcaaaag aaaaaccagg cgtccaagat gctgaatacc tggagttccc
    36661 actcccacgg tagattgttc ttgaggagta aagcaaaaac agacaatgca aatgctatag
    36721 aaaatgactc cccagaccaa aatatgatta taagtcttct tcatcattaa ggatttaccg
    36781 ctgcgactgc cttctggcgg tcacgtttca ttgtgttaga gcgcaattgt ccacaagctg
    36841 cgtcaatatc tgtaccatgc tcttgacgaa ccacacagtt gacccctttt ttcttaagcg
    36901 tatcatagaa agccaacacg cgctctttgg gactacggct atattggtca tgctcactaa
    36961 ctgggttata aggaatcaag tttacataag acaatttctt gatgttcttg agcaattcag
    37021 tcaattccaa ggcttgttct acactgtcgt tgacttcatt aagcatgata tattcaaagg
    37081 ttacacgacg gtttgttgtc tcaatgtagt attcaatagc agcaaagagt ttttcaatcg
    37141 gaaaggcacg gttaatcttc atgatacttg aacgaagttc attgttaggt gcgtgaagag
    37201 acacggcaag attgacctga accccttcat cagcaaagtc acgaatttta tgagccaaac
    37261 ctaaggttga aaccgtgatg tgacgagcac cgatagtcat tcctttatca tcattgatag
    37321 tacgaaagaa attcaagaca ttgttgtaat tatcaaaggg ctcaccgatt cccatgacaa
    37381 cgatatggct gacgcgttca tcctgaccac gctcatcaaa gtatttctga accagcatga
    37441 tttgcgctac gatttcaccg ttattgaggt cacgttgctt cttaatcaaa ccagaggcac
    37501 agaaggtaca accgatatta cagccgacct gagtggtcac acagacagat aaaccatagt
    37561 gttgacgcat gagtacagtc tcaattaaca taccgtcggg caattcaaag agatatttga
    37621 ctgtaccatc agcagactct tgcacaatac gttgtttcaa gggattgacc acaaactggt
    37681 cattgagctt agcaatcaaa tccttggaaa ggttggtcat ttcttcaaat gactgcacac
    37741 gtttacggta gagccattcc cagatttgat ctgcacggaa tttcttttct ccctgctcca
    37801 atacccattc ctgcatggtt tgatgtgcca aactatgaat tgagggtttc atttcttctc
    37861 cttattctct actcacttct gacgaatgac aaaatgacgt tgtcccttgt cctctttctg
    37921 agaatgctgg tctttctgac gacgtctatt cttcttatct gcattcgact ttcgtttagt
    37981 ttgagtcggt ttctttcctt ttctagaagg tgtttcttct tccgtcttac gcattttctt
    38041 gtcaaatgat gctcgcttag gggcttcatt ttctaagaca aaataggcac aaccataact
    38101 acaatactct aaaaggtagt cttgtaaacg actgattttt tcaagttttt cttctgttcg
    38161 gtcatccttg taaaaacctc gtaggcgaag ctgttcgttg ctccagtccc ccacgatata
    38221 atcaaacttg gttaatactt ctgaaaaacg ctgattaaaa gtcgtcacat caaaggcatc
    38281 cttgatattt tcaaccaagg aaaaagctat cccttccgtt tcgaccttgt ccccgtgtaa
    38341 atggaactcc ggaccaggaa acttgttata gttgtataat tcaggtgcaa tttcttttcg
    38401 catagatatc ctttttccac gattacttaa tactttattc taccataatt tctagcagtt
    38461 agcacgtttc tcataaaaat gaaaaaagtc tgacgatttt gtcagaccag aatcttataa
    38521 cctaaaaaga gaagaacaat tcttccctcc aactatcatt atttagcagc tgcgtacaat
    38581 tcatctactt tattccagtt gattactgaa aagaaagctt tgatgtagtc aggacgcacg
    38641 ttgcggtatt tcacgtagta agcatgttcc caaacgtcca agcccaagat tggtttttta
    38701 ccttctgaga ttggtgtgtc ttggtttgct gttgaagtca cttcaagttt cccttctttg
    38761 ttgacaacca accatgccca acctgaacca aaacgagttg ttgctgctgc agtgaaggct
    38821 gcttggaatt cttcaaatga accaaatgtt gcatcgattg ctgctgccag ttctgctgaa
    38881 ggagctgttt tctcgggagt catcaattcc cagaaaagag cgtggttcaa gtgtccgcca
    38941 ccattgttga taagtgcttg acggatatca gctgggatag attctacatc agcaagcaag
    39001 gcttcaaggt cttcaccgat ttcagggtgt ttttctaaag ctgcattggc attgttgaca
    39061 taagtttgat ggtgtttgtc atggtgcaaa tgcattgttt ccgcatcgat gtatggttcc
    39121 aaagcgtcgt atgcatatgg aagttctggt aagataatag ccatctgtaa tacctctttt
    39181 tctttctata tgaaaatgat aacgcaaaca ttcacttttt tcaagttttt tgcttataga
    39241 taaggaaatc actgacatac tttctaataa aataagcaaa tcagcaagaa acccacgaca
    39301 agataatcct gacgcgggtt gtagtttcaa caaatgtcaa ttgacctgac tagcaatctg
    39361 taagagtgcc ttttcaaaaa ggaaaccttt ttcataaaga cctgtcttaa tctgatagtc
    39421 tgtctcaatc aaataggaaa tagcttgctt cagaaagctc aaagaaagtc ctctcgaatc
    39481 tcttaatgca aacttgattt gataaggatt tgggttacgt cccagataac tacctaaact
    39541 acttgcaatc tgcgattctg tttggccaga ctccgccaaa atcttcacct gagtaaaagt
    39601 ccgaaattgt cccagcatga ctgcaatcag tttgatttca tcttcccctt gcaaggtcaa
    39661 gtctctcacc aaatcgcgcg cctgatccat ctttttagtc agaataaact gagttaaatc
    39721 aaaaatattg tcctgcaagg tcttgggaat tgcgttaaca atatcctctt cctcgataac
    39781 agaatccgcc ttataggact gtaaaaagag aagatttttc tggatttcgc taaattgaaa
    39841 ccccgacttg atgaggagat tttcaaaaga atgattggta aactgcagac cttgtttctg
    39901 actccacttt tggaaatact ggcgcaattc ttgttctttt acttctactg catcgaagac
    39961 cttggcatca cgcttaagta atttgactaa ccgtcttttg ctatccagct ttccttctgc
    40021 aaagattatc aacttggttg ttggagaagg attgtcaagg tattcctcaa atgacttaag
    40081 ctcatcatct gtcaaaaagc gtttcttagc agtcgtgata tccataaaat aatctaatat
    40141 cacgattttc tcatccgcaa agaaaggaag gctgaccaac tccagttcca catccttgta
    40201 aactacttct ttcatatcaa agtaggcaaa gttgaggtca gcagaatcat acccaatctg
    40261 tttcaacact tgactcttca tcacttcaaa ctgaccctga tctgtccctg taaataggct
    40321 caggctcggt aaatttgata aagtcaactt ctgactttct tcaatggcta gcatcgtctc
    40381 tcctttcttc agatttttcg atttaattta gtcaatatag cgcaatttcc cacggaaatc
    40441 ttctaagctc tcgtagcctt tttccaccat gattgctttc agttcattgg taatgcggtc
    40501 aaaagcactg acgccttctt tgtgaagggt cgttcccacc tgcaccatac ttgctccaca
    40561 gaggatgtgt tcaaaggcat ctcgaccagt cagaacgcca cctgttccga taatttggat
    40621 ttgaggattt aaacgttgat aaaaggcgtg aacattggct agagcagtcg gtttgatgta
    40681 ttctccacca attccaccaa aaccattctt aggccgaata acgacagatt cgtcttctat
    40741 atagaggccg tttccgatag agttaacgca gttgacaaac ttgagcggat atttgttgaa
    40801 aatagctgcc gcttgatcaa agtgaacaat atcaaaataa ggtggcaatt taattccaag
    40861 aggtttggtg aagtaagcaa acacttctgc caaaatccgg tctgttgtct caaaatcata
    40921 ggcaatctga ggtttacctg gaacatttgg acaggaaaga tttagctcag tcagaccacg
    40981 aaaatcactc tcttggactt ttttcaaaat agtatgggtt tcctctggag acatgccgac
    41041 cagagataag aagaaagttc ggttcgactc tttttcctgc aaatctaaaa gataatccaa
    41101 ataatagtct aagccattat ttggcaagcc catagagttg atggaaccaa gtggaacatc
    41161 ttggtagcgt ggctcaggat tcccctgacg gaagtccaag gtcgctgtct tagtaacaaa
    41221 ggttcctgcc gctgagtttt tgacctcttc taactcctct atcgtcatac aagccacacc
    41281 tgctgcattc atcaagcaat tgtcaaactc aaaaccagca atttgtgttt tcgttgatac
    41341 catgattcta atcctccaga tttcttttat tgctaatatt ataccataat tttaattcta
    41401 ggtttactag attctgtggt tctatctatt tattcggaaa agaaagtcta gtacagaagt
    41461 catgctatgg aaacagctag tgtattagaa gtttgaacaa ggcttgggta acagactttt
    41521 gaatgaagtc caagcaacaa ggagaaatct caaccatgag tccattccat gactctgttg
    41581 ctctagaaaa ccttgcaata gtcaagtgat aacgaataaa actttggatt gaaatatccc
    41641 caagattatc tattacgagg agaaatctta acctttatca tttttaaaga aatatagtaa
    41701 aatgaaacaa gaacaggaga aatcgatcag gacagtcaaa ttgattgcta acaatgtttt
    41761 agaagttgag gtgtactatt ctagtttcaa tctactatac atgtaaatct ctactttcgc
    41821 aaaatggatt ttcagaacag tatcccagta tagttaaaaa ctataaaaaa gagaggacgt
    41881 tcccctctta aaatcttatt ttactgcttc tttcaaagca tctaccttat ccaaacgttc
    41941 ccatggaaga tcaatatctg tacgtcccat gtgaccgtaa gccgatgttt gacggtaaat
    42001 tggacgcttg aggtccagca tttggataat ccctgcaggg cgaaggtcaa agatttgacg
    42061 agccgctttt tcaagttgac tttcagctac tgttcctgta ccgaaagtat cgatacgaac
    42121 agaaacaggt tgcgcaacac cgatagcata agccaactgc acttctgcct tcttagcaag
    42181 gcctgctgca acgatattct tggcaatata gcgagccgca taagaggctg aacgatccac
    42241 cttagtcgca tctttaccag agaaggcacc accaccatga cgagagtagc caccataagt
    42301 atctacaata atcttacgac cagtcaaacc tgagtcccct tgaggaccac cgattacaaa
    42361 acgacctgtc ggattgataa agaattttgt cttatcatca agataagaag atggaataac
    42421 ttctttgatg accttgtcaa tcacatcttg atggatttgt tcattagtgg cctctggatc
    42481 atgctgagta gaaataacga ctgtatctac acgtaccgga cggtcatttt catcgtactc
    42541 aactgtaact tgtgattttg catctggacg gagatagcta atttctccag acttacgaag
    42601 ttctgccaga cgacgaacca atttatgact gagtgcaatt ggcaatggca taagctcttc
    42661 tgtttcatct actgcaaatc caaacatgag cccttggtca cctgctccaa tcaagtccag
    42721 tggatcttga tcagcatttc cacgaacctc caaggcttcg ttaacacctt gagcgatgtc
    42781 aggagattgt tccaccaaag atgggtgtac tcccaccgtc tcagcagaaa atccatattc
    42841 tgtattggta taaccaatct ctgcaatggt atcacgaacc acacggttaa tatccacata
    42901 ggcatttgta gaaatttcac caaaaacgtg gacagaacca gtatatacag ctgtttcagc
    42961 agcaacgtgc gcctctggat cctttgctaa aatagcatcc aaaatcgcat ctgaaatttg
    43021 gtctgcaatc ttatccggat gcccctcaga tacagattca gacgtgaata atttacgttc
    43081 tgacataaaa atgtcccccc ttaaaaaata ttgttataga gttacaaagt actgatagga
    43141 aaactcttcg taataaatac ctaccatctt atcgggacta tataacttta tcattatacc
    43201 atttttaatc gcaatttgca gtctttaatg tagtgtttcg gtttagatag ttcgttctca
    43261 taaagcaaaa agttggagct cagtactcca acaatttcta ttaaaatgtt tgacgtttag
    43321 ctttacgctc tgcacgaccg cgagcgcgat tttcagcacg cttggtttta cggcgctttt
    43381 catcaaccgc ccattgaatt ttcttcttat aacccggttt gacttttttc tttttctttt
    43441 taaccaaacc aatcatttcg atatcaagtt tatcttgttt tttctcacgg ttggcacgac
    43501 gatcacggtc ataggtatct tgaaattccc cgtctttgac catcttagga ctaaacttga
    43561 ttcccaattt ctccaactca cggatatccg agtcatcact tggctgataa agggtaatag
    43621 ctgtacctgg taggccattt cgtccagtac gaccaacacg gtgaacaaaa aaagataagt
    43681 cttgcggaat ggcatcattg atgacatggc tgacaccttc aatgtcaatc ccacgtgctg
    43741 ccaaatctgt tgcgacaata tactcaaaat ccagattttg cacctgattc atgattcgct
    43801 tgcgttcacg aggggcaata tcgccatgga tttttgcaac cttcaagcct tgagcagtca
    43861 gatatgaatg caattcatca gcacgcgttt tagtgttaac aaaaatcatt gccaaatacg
    43921 gctgcatcaa ctgagtcaac tggtaaattt gagcattctt atcatgtccc ttggtcgaaa
    43981 tcaaccaatt atcaatggtg tcagaaataa ccgttttggt cttaattttc tccataacag
    44041 gattggataa gtattttttc aagaatggtt gcagtttttg tgggatagtc gctgagaaga
    44101 ccatgaattg caagtctttt ggaagactgc cagcaatctt atcaacagtt tccaagaatc
    44161 ccatatccaa ggtcatatcc gcttcatcaa caacaaatgt cttggcttta tgaatagcta
    44221 aatcaccaga tttaaccaag tcgtagatac ggcctggtgt tccaataaca atatgaggct
    44281 gattgcttgc caatttctca atctggcgag ccttatccgt accacccaca taattaacca
    44341 cacgaacttc gacatctgag tgagctgaaa tctgacgcgc tacttggtaa atttgagtag
    44401 ccaactcacg actcggtgca gtaatcactg cttgtacact atcgctagct tcatctaatt
    44461 gctggaaaat cggtaacaag aaagtatgag tcttacctga acctgttttt gattctccta
    44521 ctaggtcacg acctgccaaa acaataggaa tcaacttgtc ttgcacctct gttggagttg
    44581 taaattttaa ctcctccaag gcttctctaa tatagttttt aaattgaaat ttcgtaaatg
    44641 acataacatc ctcgattcta tctatcttat caattatacc atattttatt ccattacagt
    44701 agtctcactt atttaggcta tttccagtag cttctctagt aagaaaaggc tggaatttta
    44761 taccccaatt attcacccct aatctaaaaa
//
LOCUS       DAVHLA010000010        44577 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVHLA010000010 DAVHLA010000000
VERSION     DAVHLA010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44577
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.010"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(115..330)
                     /locus_tag="VVO77_000685"
     CDS             complement(115..330)
                     /locus_tag="VVO77_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692736.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNHEKFED"
     gene            complement(1201..2451)
                     /gene="ilvA"
                     /locus_tag="VVO77_000686"
     CDS             complement(1201..2451)
                     /gene="ilvA"
                     /locus_tag="VVO77_000686"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEU5692737.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(2501..2857)
                     /locus_tag="VVO77_000687"
     CDS             complement(2501..2857)
                     /locus_tag="VVO77_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEU5692738.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(3095..3331)
                     /locus_tag="VVO77_000688"
     CDS             complement(3095..3331)
                     /locus_tag="VVO77_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692739.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(3438..4460)
                     /gene="ilvC"
                     /locus_tag="VVO77_000689"
     CDS             complement(3438..4460)
                     /gene="ilvC"
                     /locus_tag="VVO77_000689"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEU5692740.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVVEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGSRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(4526..5002)
                     /gene="ilvN"
                     /locus_tag="VVO77_000690"
     CDS             complement(4526..5002)
                     /gene="ilvN"
                     /locus_tag="VVO77_000690"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEU5692741.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(4995..6695)
                     /locus_tag="VVO77_000691"
     CDS             complement(4995..6695)
                     /locus_tag="VVO77_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEU5692742.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(6896..8563)
                     /locus_tag="VVO77_000692"
     CDS             complement(6896..8563)
                     /locus_tag="VVO77_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEU5692743.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDAVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(8566..8931)
                     /locus_tag="VVO77_000693"
     CDS             complement(8566..8931)
                     /locus_tag="VVO77_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU5692744.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(9088..9276)
                     /locus_tag="VVO77_000694"
     CDS             complement(9088..9276)
                     /locus_tag="VVO77_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEU5692745.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(9392..9568)
                     /locus_tag="VVO77_000695"
     CDS             complement(9392..9568)
                     /locus_tag="VVO77_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEU5692746.1"
                     /translation="MDLDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     NGMWRAENVTQDLI"
     gene            complement(9679..9877)
                     /locus_tag="VVO77_000696"
                     /pseudo
     CDS             complement(9679..9877)
                     /locus_tag="VVO77_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
     gene            complement(10305..11849)
                     /locus_tag="VVO77_000697"
     CDS             complement(10305..11849)
                     /locus_tag="VVO77_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEU5692747.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNKRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLETFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            12062..12364
                     /gene="gatC"
                     /locus_tag="VVO77_000698"
     CDS             12062..12364
                     /gene="gatC"
                     /locus_tag="VVO77_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEU5692748.1"
                     /translation="MKITQEEVTHVANLSKLRFSEKETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEKDNYYIKVPAILDDGGDA"
     gene            12364..13830
                     /gene="gatA"
                     /locus_tag="VVO77_000699"
     CDS             12364..13830
                     /gene="gatA"
                     /locus_tag="VVO77_000699"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEU5692749.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQTTLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLSAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGIDPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            13830..15272
                     /gene="gatB"
                     /locus_tag="VVO77_000700"
     CDS             13830..15272
                     /gene="gatB"
                     /locus_tag="VVO77_000700"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEU5692750.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNTEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            15401..15961
                     /gene="efp"
                     /locus_tag="VVO77_000701"
     CDS             15401..15961
                     /gene="efp"
                     /locus_tag="VVO77_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEU5692751.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            15983..16372
                     /locus_tag="VVO77_000702"
     CDS             15983..16372
                     /locus_tag="VVO77_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU5692752.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            16365..16787
                     /gene="nusB"
                     /locus_tag="VVO77_000703"
     CDS             16365..16787
                     /gene="nusB"
                     /locus_tag="VVO77_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEU5692753.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQMVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(16837..17073)
                     /locus_tag="VVO77_000704"
     CDS             complement(16837..17073)
                     /locus_tag="VVO77_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU5692754.1"
                     /translation="MDVILSAIIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDN
                     LRLTILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(17086..17559)
                     /locus_tag="VVO77_000705"
     CDS             complement(17086..17559)
                     /locus_tag="VVO77_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692755.1"
                     /translation="MRNTKKLRQFGIFLLIILLSTYLPQTIGLYVTIILGLGADVYSL
                     ILTMGLVGSFLLLIWRLKKKKMLFIFEKKSWNWSFVFYLFATYVVYQILGNFWARYAH
                     LINHRNIHDEYFTVLFSNGQPTFLSTILSFVLPVIIGPVFEETLDRGYFMNTFFP"
     gene            complement(17577..17762)
                     /gene="briC"
                     /locus_tag="VVO77_000706"
     CDS             complement(17577..17762)
                     /gene="briC"
                     /locus_tag="VVO77_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HEU5692756.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(17921..18688)
                     /locus_tag="VVO77_000707"
     CDS             complement(17921..18688)
                     /locus_tag="VVO77_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEU5692757.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEIGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(18685..19551)
                     /locus_tag="VVO77_000708"
     CDS             complement(18685..19551)
                     /locus_tag="VVO77_000708"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEU5692758.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(19588..20955)
                     /gene="accC"
                     /locus_tag="VVO77_000709"
     CDS             complement(19588..20955)
                     /gene="accC"
                     /locus_tag="VVO77_000709"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEU5692759.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVKKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(20967..21389)
                     /gene="fabZ"
                     /locus_tag="VVO77_000710"
     CDS             complement(20967..21389)
                     /gene="fabZ"
                     /locus_tag="VVO77_000710"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEU5692760.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGTLTFAIGN"
     gene            complement(21386..21871)
                     /locus_tag="VVO77_000711"
     CDS             complement(21386..21871)
                     /locus_tag="VVO77_000711"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEU5692761.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(21874..23109)
                     /gene="fabF"
                     /locus_tag="VVO77_000712"
     CDS             complement(21874..23109)
                     /gene="fabF"
                     /locus_tag="VVO77_000712"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEU5692762.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(23131..23862)
                     /gene="fabG"
                     /locus_tag="VVO77_000713"
     CDS             complement(23131..23862)
                     /gene="fabG"
                     /locus_tag="VVO77_000713"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEU5692763.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(23896..24816)
                     /gene="fabD"
                     /locus_tag="VVO77_000714"
     CDS             complement(23896..24816)
                     /gene="fabD"
                     /locus_tag="VVO77_000714"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEU5692764.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(24809..25783)
                     /gene="fabK"
                     /locus_tag="VVO77_000715"
     CDS             complement(24809..25783)
                     /gene="fabK"
                     /locus_tag="VVO77_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEU5692765.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     VSIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWTGVVRND"
     gene            complement(25903..26127)
                     /locus_tag="VVO77_000716"
     CDS             complement(25903..26127)
                     /locus_tag="VVO77_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEU5692766.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(26187..27161)
                     /locus_tag="VVO77_000717"
     CDS             complement(26187..27161)
                     /locus_tag="VVO77_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEU5692767.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(27161..27595)
                     /locus_tag="VVO77_000718"
     CDS             complement(27161..27595)
                     /locus_tag="VVO77_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU5692768.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(27689..28474)
                     /locus_tag="VVO77_000719"
     CDS             complement(27689..28474)
                     /locus_tag="VVO77_000719"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEU5692769.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            28844..30208
                     /locus_tag="VVO77_000720"
     CDS             28844..30208
                     /locus_tag="VVO77_000720"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEU5692770.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREIGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYYAFFGE
                     SKED"
     gene            30211..30582
                     /locus_tag="VVO77_000721"
     CDS             30211..30582
                     /locus_tag="VVO77_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEU5692771.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKVSRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            30796..32070
                     /gene="serS"
                     /locus_tag="VVO77_000722"
     CDS             30796..32070
                     /gene="serS"
                     /locus_tag="VVO77_000722"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEU5692772.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGTDEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(32095..32994)
                     /locus_tag="VVO77_000723"
     CDS             complement(32095..32994)
                     /locus_tag="VVO77_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEU5692773.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(33104..33652)
                     /locus_tag="VVO77_000724"
     CDS             complement(33104..33652)
                     /locus_tag="VVO77_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEU5692774.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(33870..35186)
                     /locus_tag="VVO77_000725"
     CDS             complement(33870..35186)
                     /locus_tag="VVO77_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEU5692775.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMALIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALTQS
                     AFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGARFIWLYRVFFVLMVL
                     LGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFNK"
     regulatory      complement(35277..35365)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(35529..37865)
                     /locus_tag="VVO77_000726"
     CDS             complement(35529..37865)
                     /locus_tag="VVO77_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEU5692776.1"
                     /translation="MNKKILETLELDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLTSREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKVKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYVEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(37969..38517)
                     /locus_tag="VVO77_000727"
     CDS             complement(37969..38517)
                     /locus_tag="VVO77_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEU5692777.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(38514..38816)
                     /gene="zapA"
                     /locus_tag="VVO77_000728"
     CDS             complement(38514..38816)
                     /gene="zapA"
                     /locus_tag="VVO77_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEU5692778.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            38903..39784
                     /locus_tag="VVO77_000729"
     CDS             38903..39784
                     /locus_tag="VVO77_000729"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEU5692779.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFDYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLNFC
                     AKLHFKNTEKAKKRLER"
     gene            39788..40402
                     /gene="lepB"
                     /locus_tag="VVO77_000730"
     CDS             39788..40402
                     /gene="lepB"
                     /locus_tag="VVO77_000730"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEU5692780.1"
                     /translation="MNSLKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKLLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            40482..40604
                     /locus_tag="VVO77_000731"
     CDS             40482..40604
                     /locus_tag="VVO77_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chlorohydrolase"
                     /protein_id="HEU5692781.1"
                     /translation="MKIKEQTRKLAVGCLKQWFEVVDRTDEVSSKYCFEVADGS"
     gene            40681..43047
                     /locus_tag="VVO77_000732"
     CDS             40681..43047
                     /locus_tag="VVO77_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEU5692782.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLIRILEKGEQKRQDLETIQKHITTVEQELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLTNQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGVALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKRDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(43095..44378)
                     /locus_tag="VVO77_000733"
     CDS             complement(43095..44378)
                     /locus_tag="VVO77_000733"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEU5692783.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
BASE COUNT        13008 a        10183 c         8417 g        12969 t
ORIGIN      
        1 aaataaaaag aaaaggctgc atcaaccgtg cagtcttttt gctgtcctca aaatgaaaag
       61 gcagattctc tatctctact acttgaaggt caagaatcca ccgttatcca aagattaatc
      121 ttcaaatttt tcatgatttt tttcatagaa atcaattaag cctagggctg tttcaaatga
      181 aatatttttt acttttgcac gaccctgcgc cagagcaatg atagacattt cacgcgcatt
      241 cgtttcttta gagatacggt agcctgtgat tttcttatca cgaacccagc caacaactga
      301 ttctactttt tcaaagtttg acttagccat gtttttctcc tattttcttc tttataatat
      361 ttaattgtat acgtttttac tacttttgtc aataaaaaaa acatatattc aacgaaaata
      421 attagttcag aattttctta cttccttttt aaatccgata atatataggt tttgctagcc
      481 tctacaccat aaatatttgc taataaaaat actgtattat taccctctta aggtgcgaaa
      541 ttattcaagt tcttaaaaaa tgcttctcta tttccgtaag atagcttatt tcttcgattt
      601 aagaactgaa gatgatagtt ctaaccttta gaaatccaag ccttctctag ctcaaaaact
      661 cctatctttc ttcctcaata aatcatctga gagataggta ttccttatat ccttcaaatt
      721 catcactcct ttggatattg aggtgctagc ctagaagcag acacccgatt atctaaacca
      781 tccttaatag agatgacaag acagataagc tcagttaatt acttatatat ctttttaata
      841 tggtatattt gtcaacaaaa agaaatcaaa tcatacctta tactcaatga aaatcaaaga
      901 gcaaactagg aagctagccg caaattgctc aaaacactgt tttgaggttt cagatagagc
      961 taacgtggtt tgaagagatt ttcgaagagt attaaagaca gtatgactat gcttgtcaat
     1021 agataggaaa tcaaaatgaa ggatggaaat ctgagccaaa catcataagt gctataatga
     1081 acagaagtaa gaattgcacg ataagttttc taaaaccata ggaatcgtcc cctttcttca
     1141 tcttcattat agcacatata catcagttgt acaaataata tgatattttt ttattagtcc
     1201 tcagacaagc atattataaa gcgtttcatt accatttaag ttaatataag ctggatcaaa
     1261 accttccatt ctacggatca aacctgcata atcatgctta tctgccaaag cgatcccaat
     1321 caatactggg cctgttccct tgctagctcg tttgatatac tcaaaacgtg tgatatcatc
     1381 atttggcccc aggatatcat ttacaaactc acgcaaagct cctggacgct gtgggaaatt
     1441 gaccacaaag taatgtttga taccatcata aatcaaggca cgctcttcca tttctggcat
     1501 acggttgata tcattatttc ctccagaaat gatacaacaa atggttttcc ccttaatata
     1561 ttcagctaaa acctctaaag aggcgatact agccgctcca gcaggttctg cgactatccc
     1621 ttgcttagag taaaggtcaa tcaaggtttc agaaatcaat ccctcatcga cacctaccaa
     1681 agtttgaata tgttgacgag ttgcttcata ggtcaactga cctacctttt gcacagcaat
     1741 cccatccgca aatttatcaa tttccttgag tttgactgga cctccagcct caaaggcagc
     1801 tttcatggaa cgcgctccat tcgcctctac tccgataacc tcaatctctg gacttgtttc
     1861 cttgatatag gtagaaaccc cggcaatgag accgccacca ccaacaggaa ccaagacagc
     1921 atcaaaatca atcgattctt ttcgagcttc ttctaaaatc tcataagcaa ctgttccttg
     1981 acctgcttga acatgagcat catcaaaagg atcaataaag gtacgatttt cagagactgt
     2041 aaattcttga gctgctttgg ctgaggcatc aaaggtatct ccaactagtt taatagttac
     2101 aaaatcccca ccaaaaaagc gaacctgacc aatcttttgt tgtggcgtag taataggcat
     2161 aaagatagta gcaggaattt tcatttcatt acaagtatag gctactccct gcgcatgatt
     2221 tcccgcagaa gcgcagacta ccccacgttc acgttcttcc ttgctgagct gggaaatggc
     2281 ataataggca ccacgaattt taaaggagcg aacacgctgg gcattttctt ttttcaaata
     2341 aatcttagca ccatacttct ccgataaata atgatcgtaa tccagtggag tattcacaac
     2401 cacaccgttc aagaccttgt gagccttgat tatatctttt gaacttaaca tataaaacct
     2461 ctttttctat aaaaaacagt cactaatgac tgttttttag ttattcatct ccgaaaactt
     2521 cagtaacact ttcatggtat ttatgagcca tacgaatcga aaactcttta ggaagttcat
     2581 aacgatttgt ggaaatccaa tcatataacc attctaccaa actttcttca ctatcattac
     2641 gatggaagat aaaatagttt aaaatttctt tatattctac atcattcaaa tccaacgtgt
     2701 ctacaaattg actacgagga acaaaattag aatctaattt tcttagttga tctgtcaatt
     2761 ctcccaattg taaatccaac tgaaaaaata gtttttgcag ttgcctatca gtttcatcac
     2821 atcctgtctt gatagaaaac aaattggtaa tattcatatg atttcaaccc ctaaataagt
     2881 acatctaata tcccacgaat agctgaagct aaagttttcg cagtccagtc atttaaaccc
     2941 gattctttca atccagatgc aataatttgc tctatttgat ataaaccgcc atctatcgtc
     3001 tcatttattc tgcgaagagg accttcaata taggataaag cttctccgaa tctaacagct
     3061 gatttaggtc ctaatgattt accaactata tttgttaatg ttttttattt ctcaaaatcc
     3121 atttcgctat ataacgagca gatttagtcg caccagctct ctcaaacgga gaatgaattt
     3181 caagaccttc ttctctagct atttgtgcca atttgaagaa ttgttcaaag gtcatatgca
     3241 acctaccatc ttcaaaatta gcatcatcat aaatgttaat tacagcattt tcatcatacg
     3301 accaatctgc tttattttgg tctgctagca ctattaccga cggtgtaatt acattataca
     3361 actagaacca ataataacga tgcaattttt ctcataatct ttttcataaa atcatctcca
     3421 gcgctatata tttctaatta gttatagatt ttgaatgcat catcgtcgtt tttaccaaca
     3481 aatggcattg ctttacgcaa ttctgcacca actttttcaa tttcaaggtt agctgcttgt
     3541 tcacggtaag cagtcaattt tggacgtcca gctttatagt catttacaaa gtcatttgca
     3601 aatttaccat tttggatgtc tgccaagaca gccttcatat tttctttaac ttgttcagtg
     3661 attacacgtg aacctgatac atagtcaccg tattcagcag tgtttgaaat agattgacgc
     3721 attttcttga atccaccttc gtagatcaag tcaacgatca atttcatttc gtgaagaact
     3781 tcaaagtaag ccaattctgg agcgtaacct gcttctgtca agacttcgaa acctgcttcg
     3841 ataagggcag tcaaaccacc acaaagtaca gcttgttcac caaacaaatc ttcttcagtt
     3901 tcttctttgt aagttgtttc aagaagacct acacgagccg ctccaacacc tttacaccag
     3961 tccatagcaa tgtttttagc atttcctgtt gcatcttggt atactgcata aagagctgga
     4021 acaccaaatc cttcttcgta agtacgacgt accaagtgtc ccggtccttt aggagcacac
     4081 atgaagacat ctacatccgc aggaactttg ataaattcaa agtggatgtt gaaaccatgg
     4141 gcaaatccaa ctgcgtttcc agcttccaag tttggagcga tttctgcttc gtacaattct
     4201 tgttgaattt cgtctggcgc caagatcatg ataacatcag ccaacttagt agcttctact
     4261 actgtgtaag tatcaaatcc atcttctttt gctttatcaa aagatttacc tggacgtaca
     4321 ccgataataa cgtcacgacc tgaatcacgc aagttttgag catgcgcatg tccttgtgaa
     4381 ccataaccga taacggcgat ttttttaccg tcaagtgctg ctactttaac atctttttca
     4441 tattccattt gaactgtcat agcttttctc tcttttctat tatttattgc cttttaggct
     4501 ggtttaataa atttaagttg gatttttaat cgcgggtaaa tccagttgca cccgttcgag
     4561 caatattgcg aataccgtat gggcgaatga ctcgcaatag ggcttcgctc ttttctgcat
     4621 ttcccgtcat ctgaatggta atcgagcttg gcgctacgtc taccactgtt gcacggaaag
     4681 gttgaataat cgctaaaatc tcagctctct tctcagctgg cgctgacatc ttaaccaaaa
     4741 tcacctcgcg ctccaaatga ggcttgtctg taatatctcg aatgcgaatc acatcaatct
     4801 gacgattgag ctgtttgatg atttgctcca cttcatcatg agaagcaaca tcaataataa
     4861 tagtgatacg cgatacattc ggatcttctg ttgctccaac agagatgctt tcaatattaa
     4921 cctgacgacg agataggaca cctgtaaagc gattgaggac tcctgaacga ttttgtagtt
     4981 ttgctgttaa cattctacgc atggaactgc acccccaaca tctcatgatt actcttacca
     5041 gccggtacca ttggtaacac ctgttcctta cgagaaatat ctacctcaat tagcatagga
     5101 acatcctcag tgatgacttc aaggtcttga gccaaggtct caggattgtc aaacttatag
     5161 tttttaatac cataagcctg cgccatcaat tggaaatcag gaagggtatc aaagaccgac
     5221 tctgatgttc tgccttcata gaaggattcc tgccactggc gaaccattcc aagtgaatga
     5281 ttgttcagca taaccacctt gattggcacc ttgtaaatat tcaaaatagc caactcctgg
     5341 ttggtcattt ggaaaccacc atccccaaca aacaagacta cttccttatc tgggttagca
     5401 attttagcac cgattgctgc tggaattcca aagcccattg ttcccaaacc acctgaagtc
     5461 actaactgac gctcattttg gtagggataa tactgagctg tccacatttg gtgttgacca
     5521 acgtctgtta ccacaatggc atctccattc gtcaattcac caattcgttc aataactgct
     5581 tgcggttgaa ccacacgctc tttcttgtca taagaacgaa cacgattctt gtctttagtg
     5641 actttctcaa tccacttttc agtattgttg tgaactgttg gttctgctag caacatttgc
     5701 aaggccttct tagcatctcc aactacagga atgtctgcac tgataatctt gccaatctca
     5761 gctgggtcaa tatcaatgtg ggcaacctta gcattcttag cgaaagtctt aggattcccc
     5821 gtcaaacggt catcgaaacg agaaccaata ctaatcataa agtccgcttc cgtcatggca
     5881 atatttgctg cgaatgaccc gtgcatgcct cccattccaa gaaagagtgg gtgactcgtt
     5941 gcaatcgttc cttgtcccaa aagactggtt accactggaa tttgatagcg ttctgcaaat
     6001 tcatttagtt ccgtagcagc ctcagcataa ctaattccac caccagctaa caagactggc
     6061 tttttagcct tggacaattg cttcaagatt ttcttgattt gcatatcatt cggctcaaga
     6121 gtcggctgat aacttggtaa attcacttct ggtgaataaa tgaagtctgt ttctaaagca
     6181 gatatgtctt ttggtaggtc aattacaact ggccctggac ggcctgtagt tgcgatatgg
     6241 acagcttccg taatgatacg cggaatatca gctgtctcac gaacttggta attgtactta
     6301 gtgattggca tggtaattcc tacgatgtct gcctcctgaa aggcatcctt cccaatccct
     6361 gctcgcgcca cctgacctgt aaagaccaaa aggggaacgc tatcgctcat agcatccgca
     6421 atccctgtaa tggcatttgt tgctcctggt ccactagtga cgacggcaac acccaacttt
     6481 ccagttgatt tggcataacc ttcagcttca tgcaaacaac cttgctcatg gcgccctaga
     6541 atgtggcgaa tgcctttaaa attatatatc gcatcataaa aaggcaaaac cgcaccacca
     6601 ggataaccaa agatggtatc aactcctaaa tcacgaagtg tttccaaaac taggtccgac
     6661 cccgtcttag gagattctaa actgattttc tccattgttc ccctttcttt cctcttaaaa
     6721 ataacttgtt actatcatac cattttttca aaatttttca agataaaaga agaaattttc
     6781 tgaattttct attttaacgt ttatttatga atgttatttt tgtttttatt aaaaagatac
     6841 cgatttcatt tactaaaaaa gaaaaaagaa ctgatttctc agtccttcat taatcttatt
     6901 ccacactaaa taggtatggg taaacaggtt gttgaccttg gtgaatctcg acttcaacgt
     6961 cttcgaattc ttctacgatt tcttgagcga tttcattggc aagttcttcg cttccgtctt
     7021 caccgacata gaaggttacg atttcactat cttcatccaa catatgtttc aaggtttcag
     7081 tcaatgtttg gtgcatatca gggtttgaca caagaatttt tccatccacc atacctagat
     7141 tatcgttttc atggatttct aagccatcga tcgttgtatc acgcacggct gttgtgacgc
     7201 ttccgctaac gacatcgcta agagcagctg tcatacgctc ttggttttct tcaatggact
     7261 tgcttggatc aaaggcaaga agacttgtca taccttgagg aagagtgcga gcctctacca
     7321 ctactgctgg ttgctccaaa acttctgccg cagattgagc tgccatgaag atgttcttgt
     7381 tgtttggcaa gaagatgatg ttacgggcat tgacctgttc aacagccttg ataaagtctt
     7441 ctgttgaagg gttcatggtt tgaccgcctt cgataacata atccacgcct tgagaacaga
     7501 agatatctgc tagaccttta ccagccacca cagcaatcaa agcatactct ttttcttcag
     7561 ccgacttgat aacttgagta gcttctttct caacctgtgc ttcgtgttgg ttacgcatat
     7621 tgtcaacttt taccttgacc aagctaccat atttgagacc ttcttgcata acaagtcctg
     7681 gatcttctgt atgaacatgg actttgacaa tttcatcatc gttaacaacg aggagagaat
     7741 ccccaagctc atccaagtag ttacggaatt catcgtagtc aaaatcttta gcataggttg
     7801 gaccttgctt aagagctacc atgatttcag tacagtaacc aaacgtgatg tcctcagtcg
     7861 ctacgtgacc agctacagac ttatgatgct ctacattgat catctcactc atgttggcag
     7921 gagtcgctac aaagtcctca gatgcaatat attcgccagt aagggctgaa aggaaacctt
     7981 cgtagatgaa gaccaatcct tgaccacctg agtccacaac gccaacttct ttcaatactg
     8041 gaagcatgtc tggtgtttta gctagagctg ttttagcacc ttccaaggct gcgcgcatga
     8101 cttcaacagc gtcatctgtt tgctcagctt ttttcttagc accgatagca gctccacgag
     8161 aaactgttaa aatcgttcct tcaacaggtt tcatcactgc cttataggca acttccacac
     8221 ctgattggaa ggccagagcc aagtcttgac ctgttaactc gtctttatcc ttgatagctt
     8281 gggaaaatcc acggaaaagc tgagacgtaa tcactcctga gttcccacgc gcacccatca
     8341 aaagcccttt ggcaagaatg ctcgctactt ctccaactgt agaagctggc ttgtctgcaa
     8401 cttctttagc accattttca atggtcattc ccatatttgt cccagtatct ccatctggaa
     8461 ctggaaagac gtttaatgaa ttgacatatt cagcttgctt attcaagcga gttgatgcag
     8521 cctgcaccat ttcttgaaat aagctagtag taatttttga cacggttatt ctcctacaac
     8581 tttgatattt tgaatgtaga catttacagt ctgagcagta attccaagct ggttttccaa
     8641 gctaaaggca acacgctctt gaatgttttt tgacacttca ctaatctttg ttccgtagct
     8701 taacacggta tatacatcaa ctgcaatact gccatcttcg gctgccttta cgacgacacc
     8761 tttagaataa ttttccttac ctagcagggc ttggaaatta tctttgaggg catttttact
     8821 agccataccg accacaccaa aaatctcagt tgctgctcca cctacgacgg ttgcaatcac
     8881 ttcatctgtt agttcgattt gaccatcttt tgtattaatt tttacagtca tcctttttac
     8941 ctcaactagt tgatactcta ttttatcata tttcagccca agtgtaaaag cagaatgatg
     9001 tatcagcgga tatttactct atttttcaaa cgatgttata cccacaataa aagaaaaaag
     9061 accctaaggt ctcctttgct tttattatta aacgcgttca actttacctg atttcaaagc
     9121 acgagctgaa gcccaaactt ttttaggttt accatcgata agaacagtaa ctttttgaag
     9181 gtttggtttt acggcacgtt ttgtttggtt catcgcgtgt gaacggttgt ttcctgatac
     9241 agtcttacga cctgtaaagt aacatacttt agccattgtg ttttcctcct attagatcta
     9301 atatagcgga tgtgctagca ccacataccg tactatgtta tcacactttc ttgttttttg
     9361 caagggaatt ggaagatttt ttatttgtgt cttaaatcag gtcttgcgtg acattttctg
     9421 ctctccacat gccattgttg attaacagaa caccagaatt aaaattatgt gtataaaaat
     9481 catctctaac tgcagctaag ggtatagccg tcaagtccaa atcccacagc tcatctatcg
     9541 attttcttac aacaatatct aaatccaaat acagtacacg agactcgctt acatactttg
     9601 gaataaaata cctaaaaaag ccgcatatga aagtccctca aaggggagac gataaccttt
     9661 cagaatacta ctgtcaatct aaacattcac aatctcacta ttcaaagtct ctagtctttt
     9721 ttccatcaat tggaaccatt ctcgcggaag gtcatcatta aaaacataaa acttaagatt
     9781 ataatagatg aacacaaaga gattttattg ttgtttcaac tttatccata taagcattat
     9841 ctgcacctaa gacaatcgct tttttctctt ctttcactct ttatctcatt tctttttatt
     9901 cccatcatat gtttctacgt aaccattatt ttcgcccatt cgttcgtaaa accataccag
     9961 tggagatttt agatgaagtc ccattacggt ttacaatttt tacattacga cacggagttt
    10021 tacaaatcga tttcatttgc caaacgtagt tagtaaggca gttagctagg ctacctactt
    10081 tctgctacga cggaaaaatc cacaaatcaa taccattcgt ggatttttcc tagtgaagcg
    10141 tttaggtaag ccgccatagc ggttaccgat tattagatta cgacacggag tttggcaaat
    10201 cgattctatt tgccaaacgt agttagtgag gcagttagct agttcgccaa atagcgacta
    10261 gcgtccaaca atttggaact ttagttccaa ttgttggtac tgagtcacat cttctcctct
    10321 aactctacgt ctggatactt gtccgcaaac cagcggaggg caaagtcatt ttcaaagaga
    10381 aagactggtt ggtcaaaacg gtctttggct aagatattgc gacttgatga catccgttca
    10441 tccaaatcct caggcttgat ccaacgaacg gtctttttac ccattgggct catgaccact
    10501 tccgcattat attctccttc catacggtgc ttaaagactt caaactggag ttgacctaca
    10561 gcgcctagca tgtactcacc tgtttggtaa ttcttataaa gctgaacggc tccttcttgc
    10621 actagttgct caatcccctt gtggaaggat ttttgcttca tgacattctt agcagaaact
    10681 ttcatgaaaa tttcaggagt aaaggttggc aatggttcaa attcaaattt gtttttccca
    10741 actgtcaagg tatccccaac ctgataagtg cctgtatcgt aaaccccgat aatatcacct
    10801 gccacggcat tggtcacatt ctcacgactt tccgccataa actgggtaac attagacagt
    10861 ttagccccct taccagtacg agggagatta acactcatgc cgcgctcaaa ttcgccagat
    10921 acgatacgga caaaggcaat acggtcacgg tgacgagggt ccatgttggc ttggatttta
    10981 aagacaaagc ctgagaaatc cttgtcataa ggatccacaa tttcaccgtc tgttttcttg
    11041 tgaccatgtg gttctggagc aaacttgagg aaggtttcaa ggaaggtctg cacaccaaag
    11101 tttgtcaggg ctgaaccgaa aaagacaggc gtcaattctc cagccagaat agcttcctct
    11161 gaaaactcat tcccggcttc atttaaaagc tcaatatcat ccttgacttg ctcgtagaaa
    11221 ggattgctac caaaaagttt gtccccatct tctagactag caaaacgctc atccccttta
    11281 taaagctcta aacgtttgtt atagaggtca tacaagccct caaaggcttt ccccatcccg
    11341 ataggccagt tcatagggta gctagcaatg cccaagattt cttccaattc ttgtaagaga
    11401 tccaaaggct cacgaccgtc acggtccagc ttgttcataa aggtaaagac tggaatgcca
    11461 cgatgtttca caacctcaaa caatttcttg gtttgagcct cgatcccctt ggcagagtcc
    11521 acgaccatga ccgcagcatc caccgccatc aaggtacgat aggtatcttc tgagaagtcc
    11581 tcgtgccctg gcgtgtctaa gatattcacg cgcttgccgt cgtagtcaaa ttgcataaca
    11641 gatgaagtaa cagaaatccc acgttgcttc tcgatatcca tccaatcaga tttagcaaaa
    11701 gtccctgttt tcttcccttt taccgtacca gcctcacgaa tttcaccccc aaagtagagt
    11761 aactgctcag tgatggttgt tttccccgcg tccgggtggg agataatggc aaaggtacga
    11821 cgtttcttaa tttcttcttg aatattcata agttctcttt ctttgatcct ctatttttct
    11881 tgtttcaata gctgagaatg atttttacat tggattttac cattcctttc aacactccat
    11941 tatatcggat tttagcattt ttttcaattt ctatttcttt tcacttcccc ctcccttatt
    12001 tataggaaaa tatggtaaaa tagaacagac taaaaatcat catttcacga aaggatgcaa
    12061 gatgaaaatt acgcaagaag aggtaacaca cgttgccaat ctttcaaaat taagattctc
    12121 tgaaaaagaa actgctgcct ttgcgaccac cttgtctaag attgttgaca tggttgaatt
    12181 gctgggcgaa gttgacacaa ctggtgtcgc acctactacg actatggctg accgcaagac
    12241 tgtactccgc cctgatgtgg ccgaagaagg aacagaccgt gatcgcttgt ttaaaaacgt
    12301 acctgaaaaa gacaactact atatcaaggt gccagctatc ctagacgatg gaggagatgc
    12361 ctaatgactt ttaacaataa aactattgaa gagttgcaca atctccttgt ctctaaggaa
    12421 atttctgcaa cagaattgac ccaaacaaca cttgaaaata tcaagtctcg tgaggaagct
    12481 ctcaattcat ttgtcaccat cgctgaggag caagctcttg ttcaagctaa agccattgat
    12541 gaagctggaa ttgatgctga caatgtcctt tcaggaattc cacttgctgt taaggataac
    12601 atctctacag acggtattct cacaactgct gcctcaaaaa tgctctacaa ctatgagcca
    12661 atctttgatg cgacagctgt tgccaatgca aaaaccaagg gcatgattgt cgttggaaag
    12721 accaacatgg acgaatttgc tatgggtggt tcaggtgaaa cttcacacta cggagcaact
    12781 aaaaacgctt gggaccacag caaggttcct ggtgggtcat caagtggttc tgccgcagct
    12841 gtagcctcag gacaagttcg cttgtcactt ggttctgata ctggtggttc catccgccaa
    12901 cctgctgcct tcaacggaat cgttggtctc aaaccaacct acggaacagt ttcacgtttc
    12961 ggtctcattg cctttggtag ctcattagac cagattggac cttttgctcc tactgttaag
    13021 gaaaatgccc tcttgctcag cgctattgcc agcgaagatg ctaaagactc tacttctgct
    13081 cctgttcgca tcgccgactt tacttcaaaa atcggccaag acatcaaggg tatgaaaatc
    13141 gctttgccta aggaatacct cggtgaagga attgatccag aagttaagga aacaatctta
    13201 aacgcggcca aacactttga aaaattgggt gctattgtcg aagaagtcag ccttcctcac
    13261 tctaaatacg gagttgccgt atactacatc atcgcttcat cagaagcttc atcaaacttg
    13321 caacgctttg acggtatccg ttacggctat cgcgcagaag atgcaaccaa ccttgatgaa
    13381 atctatgtaa acagccgaag ccaaggtttt ggtgaagaag tgaagcgccg tatcatgctg
    13441 ggtactttca gtctttcatc aggttactac gatgcctact acaagaaggc tggacaggtc
    13501 cgtacactta tcattcaaga tttcgaaaaa gtcttcgcgg attacgattt gattttgggt
    13561 ccaactgctc caagtgttgc ctatgacttg gattctctca accatgaccc agttgccatg
    13621 tacttagccg acctattgac catacctgta aacttggcag gactgcctgg aatttcgatt
    13681 cctgctggat tctctcaagg tctacctgtc ggactccaat tgattggtcc caagtactct
    13741 gaggaaacca tttaccaagc tgctgctgct tttgaagcaa caacagacta ccacaaacaa
    13801 caacccgtga tttttggagg tgacaactaa tgaactttga aacagtcatt ggacttgaag
    13861 tccacgtaga gctcaacacc aattcaaaaa tcttctcacc tacttctgcc cacttcggaa
    13921 atgatcaaaa tgccaacact aacgtgattg actggtcttt cccaggagtt ctgccagttc
    13981 tcaataaagg ggttgtcgat gccggaatca aggctgctct tgccctcaac atggacatcc
    14041 acaaaaagat gcactttgac cgcaagaact acttctatcc tgataacccc aaagcctacc
    14101 aaatttctca atttgatgaa ccaatcggat ataatggctg gattgaagtc gaactagaag
    14161 acggtacgac caagaaaatc ggtatcgaac gtgcccacct agaggaagac gctggtaaaa
    14221 acacccatgg tacagatggc tactcttatg ttgacctcaa ccgccaaggg gttcccttga
    14281 ttgagattgt atctgaggca gatatgcgtt ctcctgaaga agcctatgct tatctgacag
    14341 ccctcaagga agttatccag tacgctggca tttctgacgt taagatggag gaaggttcga
    14401 tgcgtgtgga tgccaacatc tcccttcgtc cttatggtca agagaaattc ggtaccaaga
    14461 ctgaattgaa gaacctcaac tccttctcaa acgttcgtaa aggtcttgaa tacgaagtcc
    14521 aacgccaggc tgaaattctt cgctcaggtg gtcaaatccg ccaagaaaca cgccgttacg
    14581 atgaagcgaa taaagcaacc atcctcatgc gtgtcaagga aggggctgct gactaccgct
    14641 acttcccaga accagaccta cccctctttg aaatttctga cgagtggatt gaggaaatgc
    14701 ggactgagtt gccagagttt ccaaaagaac gtcgtgcgcg ttatgtatct gaccttggtt
    14761 tatcagacta cgatgctagt cagttgactg ctaataaagt cacttctgac ttctttgaaa
    14821 aagctgttgc cctaggtggt gatgccaaac aagtctctaa ctggctccaa ggggaagtcg
    14881 ctcagttctt gaatactgaa ggtaaaacac tggaacaaat cgaattgaca ccagaaaact
    14941 tggttgaaat gattgccatc atcgaagacg gtactatttc atctaagatt gccaagaaag
    15001 tctttgtcca tctagctaaa aatggcggtg gcgcgcgtga atacgtggaa aaagcaggta
    15061 tggttcaaat ttcagatcca gctatcttga tcccaatcat ccaccaagtc tttgccgata
    15121 acgaagctgc tgttgccgac ttcaagtcag gcaaacgtaa cgccgacaag gcctttacag
    15181 gattccttat gaaggcaacc aaaggccaag ccaacccaca agttgccctt aaactacttg
    15241 cacaggaatt ggcgaagttg aaagaaaact agacagaaca aaaccagccc taaggttggt
    15301 tttttcttct ctcccaactc ccaataacta ttttggcttt atttccagag tattttatgg
    15361 taaaatgaag agtaataata tttattaaag aggtaaaaac atgattgaag caagtaaatt
    15421 aaaagctggt atgacctttg aaacagctga cggcaaattg attcgcgttt tggaagctag
    15481 tcaccacaaa ccaggtaaag gaaacacgat catgcgtatg aaattgcgtg atgtccgtac
    15541 tggttctaca tttgacacaa gctaccgtcc agaggaaaaa tttgaacaag ctattatcga
    15601 gactgtccca gctcaatact tgtacaaaat ggatgacaca gcatacttca tgaatacaga
    15661 aacttacgac caatacgaaa tccctgtagt caatgttgaa aacgaattgc tttacatcct
    15721 tgaaaactct gatgtgaaaa tccaattcta cggaactgaa gtgatcggtg tcaccgttcc
    15781 tactactgtt gagttgacag ttgctgaaac tcaaccatct atcaaaggtg ctactgttac
    15841 aggttctggt aaaccagcaa cgatggaaac tggacttgtc gtaaacgttc cagacttcat
    15901 cgaagcagga caaaaactcg ttatcaacac tgcagaagga acttacgttt ctcgtgccta
    15961 atctctagaa agaggtcatt ctatgggaat tgaagaacaa cttggcgaaa tcgttatcgc
    16021 cccacgtgta cttgaaaaaa tcattgctat cgctactgca aaggtagagg gtgttcactc
    16081 tttttcaaac agatcagtgt ctgataccct ttcaaaactt tcactcggcc gtggcattta
    16141 tcttaaaaac gtggacgaag aactcacagc agatatctat ctctaccttg agtacggagt
    16201 aaaagttcct aaggtagcgg ttgctatcca gaaagctgtc aaagatgccg tccgtaatat
    16261 ggctgatgta gaactcgctg ctatcaatat tcacgttgca ggtatcgtcc cagataaaac
    16321 accaaaacca gaattgaaag atctatttga cgaggacttc ctcaatgact agtccactat
    16381 tagaatctag acgccaactc cgtaaatgcg cttttcaagc tctcatgagc cttgagttcg
    16441 gtacggatgt cgaaactgct tgtcgtttcg cctatactca tgatcgtgaa gatacggatg
    16501 tacaacttcc agcctttttg atagacctcg tttctggtgt tcaagctaaa aaggaagaac
    16561 tagataagca aatcactcag catttaaaag caggttggac cattgaacgc ttaacgctcg
    16621 tggagagaaa cctccttcgc ttgggagtct ttgaaatcac ttcatttgac actcctcaga
    16681 tggttgctgt taatgaagct atcgagcttg caaaggactt ctccgatcaa aaatctgccc
    16741 gttttatcaa tggactgctc agccagtttg taacagaaga acaataaaaa gaaaaagtgt
    16801 ttgatagata tcaaacactt ttttctttgc ctcccactat ctaaaaaaat gataatagat
    16861 ataattgtaa acaaaaatcc agataggttt tgcatgattg agaaagttaa aaaaactatg
    16921 gcagagaatc gttaatctca gattgtcggt agaacgataa acaagggcaa aaaagaaacc
    16981 aatcagacta taatataata aactaattgg atctctgtga gatagtatca aatggctaat
    17041 cccaaagatg atagcagata ggataacatc caaatagtac ttggactagg gaaagaaggt
    17101 attcataaaa taccctctat caagagtctc ctcaaaaaca ggaccgatga ttacaggcag
    17161 gacaaaagat aagatagtcg ataaaaaggt tggttgtcca tttgaaaaaa gcacggtaaa
    17221 atactcatca tgaatattcc tatgattaat caaatgagca tagcgtgccc aaaaattacc
    17281 gagaatctga taaaccacat aagttgcaaa taagtagaag acaaatgacc agttccagct
    17341 ctttttctca aagataaaga gcatcttttt cttttttaac ctccaaatta atagaaggaa
    17401 acttcccact aatcccattg ttaaaataag agaatagaca tcagctccta accctaaaat
    17461 gatcgtcaca tacaatccaa ttgtttgtgg taaataggta gatagtaaaa taataagcaa
    17521 aaatattcca aattgtctta gtttttttgt gtttctcatc gtactttttt gaaagattac
    17581 cctgctcgga agccgtactt ccaagcatct atataagaat taagtgcccc ttgcctcata
    17641 tagggagcaa attctctata atataaccat ctactatatc catcttccca aacagcaaga
    17701 ccacctgaag tttgctccaa gtcctcagtt gaaagaactg taaatgtatt tgtacctgtc
    17761 attgcaagta ccttcttaaa atagattgtt gtaggttcac atttatagta tatttctttt
    17821 tttgtctatt ttatagccca tctcctcaac tggcaatttt tcgacctgaa ttacattttt
    17881 ccataaaaaa tgagaccttt ctagtctcat ttagtcattc ttagtatttt ctaaatcgtt
    17941 gatagcgttc ttccagcaac tcttctagcg gtttttgtga aagtctagcc agctccgttt
    18001 ggagttcttt tttgacactc ttaatcagtt ctttactaga aagtcctatt tcagaaatca
    18061 ccttatccac cacgtccatt tctaacagtt catgcgaagt gattttcatc agttctgctg
    18121 cttccatagc gcgagtaccg tccttccata aaatggaagc aaagccttct ggactgagaa
    18181 tggcatagat agaattttcc agcatccaga cacggtccgc gacagctaga gccagagccc
    18241 cgcctgaacc accttcaccg ataataatgg cgataatagg aactttcagg tcactcattt
    18301 ccatgagatt gcgagcgata gcttcccctt gaccacgttc ttccgctccg acaccaggat
    18361 aagcacctgc tgtattgata aaggtcacaa ctggacggcc aaatttctca gcctgtttca
    18421 tcaaccgcag tgcctttcgg tagccttctg gatgtggttg gccaaaattc cgtttgaggt
    18481 tgtcttgcaa actcttgcct ttttggatac caaccactgt tacagcttga tctccaagcc
    18541 aaccaatacc accaacaact gcaccatcat cacgaaaaga acggtcacca tgtaattgga
    18601 taaattcatc aaaaatgcct gtcgcaaagt ccaaggttgt caagcgactc tgctcacgcg
    18661 cttctctgac tatttttgca atattcatct aggactccct ccatgcaatc tgactaggct
    18721 agcaatcgta tctggtaagt ctcttctttt gacaatagca tccacaaagc catgttctaa
    18781 taggaattct gccttttgga aatcctcagg caagctttca cgaaccgtat tttcaatcac
    18841 acgacgccca gcaaaaccaa ccaagctctg tggttcagcc agaatgatat cgccttccat
    18901 agcgaaagaa gctgtcacac caccagtcgt tggatctgtc aaaatggtca ggtaaaagag
    18961 accagcattt gaatggcgtt taaccgccgc agagatctta gccatctgca tgagactcat
    19021 gattccttcc tgcatacggg ctccaccaga ggctgtgaat aggacaactg gcaatttttc
    19081 gacagtcgca tactcaaaca aacgagtgat tttttcacct acaaccgtac ccatagaagc
    19141 catgataaag ttagaatcca taatcccaag agccacagtc tgacctttaa taagagcagt
    19201 tcctgtcaca acggcttcat gcagacctgt tttttcacgc atagatgcca gtttcttttg
    19261 gtaaccaggg aaatgcaagg gatccttgct ttcaatccct gtaaacaatt ctttgaaggt
    19321 tcccatatca atcgtcaaag ccaagcgttc ttgggcagaa atacgaaagg tatagctaca
    19381 gtgcggacag atacgttcac ttcccagatc cttctgatag atggtatgct tacagcctgg
    19441 acactgggaa aataattcat ctggaacctc tggcttagct tgaggttttt ccctaaccga
    19501 acgattggga ttgattcgaa tatacttatc ttttttacta aatagagcca ttgattcccc
    19561 ttttcggttt aaactcttaa agtcatttta ttctttttct tgatatttag gtaagaaggt
    19621 ttccatcaag aaggaagtat cataatcccc agcaatgaca ttgcgatctg aaatgaggtc
    19681 aagctggaaa tctgcattgg tctgcactcc ttcaatctct aattcataga gggcacgttg
    19741 cattttcatc aaggcgtcaa aacgattttc gccgtgtact atgattttgg caatcatact
    19801 atcataataa ggcggaatgg tataacctgg ataaactgct gaatccacgc gcaagccaac
    19861 tccaccactt ggcagataga gattagtaat cttacctgga cttggagcaa agttaaaggc
    19921 tgggttttct gcattgatac gacactcgat ggcatgaccg cgtaggacaa tatcttcttg
    19981 cttaacagac aaaggctgac ctgccgcaat gcaaatctgt tccttaacga tatcaacacc
    20041 tgaaacaaac tctgttactg gatgttctac ctgaacacga gtattcatct ccatgaaata
    20101 gaaattgcta cttgcttcat caagaagaaa ttcaatggtt cctgcattct catagccaac
    20161 aaactctgcc gctcgaacag cagcagcacc tatttcatga cgcagcgttt ttccgattgc
    20221 aatcgaggga ctttcttcca aaaccttttg gttattcctt tgaagagaac aatcccgttc
    20281 acccaagtga atcacatgtc catgctcatc acctaggatt tgaacctcaa tgtgccgagc
    20341 tggatagata acccgttcta tgtacatggc accattgcca taattggcct tggcctcact
    20401 agaggcagtt tcaaaggcag aaacgaggtc atctggtttt ttaaccttac gaatcccttt
    20461 accacctcca cctgctgaag ccttgagcat aacaggatag ccaatttttt cagcaacaat
    20521 caaagcttct tcagagttat gcacttctcc atctgaacct ggtataacag gcacacctgc
    20581 tttaatcatc tgagcacgcg cattgatctt atcccccatc atatccataa catgaccaga
    20641 tggaccgata aacttgatac ctacttcttc acacatggtc gcaaatttgg aattttcact
    20701 gagaaatcca aaaccagggt gaatagcttc tgcctcagtc aagactgcag ctgatagaac
    20761 tgcattaata ttgagataag actctgttgc cttgccagga ccaatacaaa ctgcttcatc
    20821 tgccaaaagc gtatgaagag cttccttatc agcagttgaa taaaccgcta ccgtcgcaat
    20881 ccccaattca cgtgccgcac ggataatacg aaccgcaatt tcaccacgat tggcaattaa
    20941 aatttttcga aacatggaga acctccttag ttcccaattg caaaagtaag ggtaccactg
    21001 gctgcaagct tgccatccac ttcagccttt gcttcaacca cagctatggt gccacgacgt
    21061 tttacaaaag tcgctgtcat aaccaattgg tcgcctggta caacttgctt cttgaactta
    21121 accttgtcca taccagcgta aaagaccagt tttcctttat tttcaggttt tgataactcc
    21181 aacacaccgg cagtttgcgc caaggcttcc ataatcagaa cacctggcat aactgggtat
    21241 tgaggaaagt ggccgttaaa gaaaggttcg ttaatggtca catttttgat agcaacaatg
    21301 gtatcctcgc tcacttccaa gacacggtcc actagaagca taggataacg gtggggaaga
    21361 gcttctttga ttccttgaat atcgatcatt tgatacgtac caatccttta ccaaactcaa
    21421 ccatttcttc gttagagacg agaatttccg ttaccacacc atccttagga gctgggattt
    21481 cattcatgac tttcatggct tcgataatta ccaatgtttg accttttttg acactatcac
    21541 caactgtaac gaaggcaggt ttatctggtc cagcagccaa gtaaaccact ccaacaagtg
    21601 gactctctac aagatttccc tcagtagcca cacttgcttc agctggagct ggaacttctt
    21661 ctgctacagt ctctgctgga gcagatgtag gagctactgg actcggtgtt gctagaacgg
    21721 gtgctggagc gacttgagtt gcaacttcag gcacaggtct tgcttcattc ttgctaaact
    21781 gcaactcatc cgtcccattt ttataagaaa attctctcaa acttgactgg tcaaattgag
    21841 tcatcaagtc tttaatatcg tttaaattca tacttatcta ttctcccaac gtttgaaagc
    21901 aagaactgca ttgtggcctc caaaaccaaa agtatttgaa atagcgtatg gaatttcttt
    21961 ctccaagcct tgtccataaa cgacattagc ttcgatataa tctgatactt cacttgtccc
    22021 agctgtcatt ggtacaaagt tatgacgcat agcttcgatg gtgacgatag cttctactgc
    22081 acccgcagcc cccagcaaat gtcctgtaaa agacttggtt gatgatacag gtacttcctt
    22141 accaagaaca gctacgatag caccactttc tcctttttca ttggcaggag ttgacgttcc
    22201 gtgagcattg acataggcta cttgctctgg agaaatctca gcttcttcca aggctagttt
    22261 gatggccttg atagctccct gaccttctgg atgtggagaa gtcatgtggt aggcatcaca
    22321 agtatttccg taaccaacca cttcagccag gatagtagct ccacgttttt cagcgtgttc
    22381 aagactttct agaaccaaca tccctgaacc ttcacccata acaaacccat tgcgatcctt
    22441 atcaaatggg atcgaagcac gagttggatc ctctgtagta gagagagctg ttaaggcttg
    22501 gaaaccagcg atggcaaaag gtgtgataga agcttctgtt cctcccacca acatcacatc
    22561 ttggaaacca aacttaatgg agcggaaggc atccccaatc gcatcatttg atgaagagca
    22621 ggcagtattg atagatttac aaacaccgtt tgcaccaaaa cgcatggcta cattcccaga
    22681 agccatattt ggtaaagctt ttggaagagt cattggtttg acacgtttgg gtcctttttc
    22741 atgaaggcga agtacctgat cttcaatttc cttgattcca ccaataccag atgcaacgat
    22801 aacaccaaaa cgatccctat taagagcctc tacatcaaga ttggcatgat ttacagcctc
    22861 ttgggctgca tacaaggcat ataaagaata gttatcaaaa cggttggtat ctttttttac
    22921 aaagtattta tcgaacggaa aatcttggat ttctgccgca ttatgcacat caaagtcact
    22981 atgatcaaat tttgtaatgc caccaatgcc gattttccca gttgctaaac tattccaaaa
    23041 ttcttctggt gtatttccga ttggagatgt tactccataa cctgttacca ctactcgatt
    23101 tagtttcatt cttttcacct ctagctttcg ctacatactt aagccaccat caatggcaat
    23161 cacttgacca gttagataat cttggcctgc taaaaatact gtcaaatctg caacctgctc
    23221 tgcctgccca aattctttca tcggaatctg agctagtgta gcttccttaa tcttatctga
    23281 taagatagct gtcatatcag actcaatcat tcctggagca atcacattga ctcgtatatt
    23341 ccgactagcg acctcgcgtg ccacagactt ggtaaagcca atcaagccag ccttagaagc
    23401 agcatagtta gcttgaccaa tattccccat caaaccaaca acactagaca tattaatgat
    23461 agcaccttct ctggctttca tcatcggttt caagactgat tgtgtcatat taaaggcacc
    23521 agtcagattg accttgagca ctttttcaaa atctgcttct gtcatcttga gcataagagt
    23581 atcttgggta atccctgcat tgttgaccaa aacatctact gaacccagtt ctgcaatagc
    23641 ttgatcaatc atacgcttag cgtctgcaaa atctgataca tctcctgaaa tgggaaccac
    23701 cttgatacca tagtttgaaa actcagcgag caattcttct gagattgccc cacgactgtt
    23761 taagacaatg ttggctcctg cttgagcaaa cttgtgggcg atggcaagac caattccacg
    23821 actcgaacct gtaataaaga tatttttatg ttctagtttc atttttttcc tttcaaaact
    23881 tctacttatt ttagtctatt tttctaaaag tgctactaaa ctcgcttgat cttccacatg
    23941 agctaagtga gcagtttgat caattttttt aacaaagcct gacaagactt tccccggtcc
    24001 aatctctata aagttgctta tgcctgcttc ttgcatgacc ccaatacttt catagaaacg
    24061 aacgggttcc ttgacctgac gcgtcaagag ctgagcaatg tcctcttttt gcatcacagc
    24121 agcttctgta ttgccgacta ggggacaagt aaaatctgaa aaacttacct gagctagagt
    24181 ttcagctagt ttctggctag caggctcaag gagagcggtg tgaaagggac ctgacacctt
    24241 aagaggaatc aagcgtttgg cacctgcttc ttgcaaaagt tcaaccgctc gatcaactgc
    24301 aaccacttct ccagcaatga cgatttgtgc aggtgtgtta tagttggctg gagtaaccac
    24361 tccaagttca gaagcttttt gacaggcttc ttcaatgacc tctactggcg tattgagaac
    24421 tgctaccatc ttgccagagt cagcaggagc cgcttcttcc atataggctc cacgcttagc
    24481 taccaaggca accgcatctt caaaatccaa ggcgccgctt gccaccaagg cagagtattc
    24541 tccaagagac aaaccagcaa ccatatcagg ctgatagccc ttttcttgca ataaacggta
    24601 gatagcaacc gaagtcgcta gaatggctgg ttgcgtatag cgggtctgat tgagtttgtc
    24661 ttcttccgta tcgatgagat aacgcaaatc ataacctagt acctggctcg ctcgatcaat
    24721 cgtttcttta acaatcggat actgatcata gaaatcccgt cccatcccta gatactgggc
    24781 accttgacca gcaaataaaa aggctgtttt agtcatttct tacaactcct gtccagcgag
    24841 aggcttcttc ttgaattttc ttagcggctc cgtaatacaa atcttttagg atttcttcag
    24901 ctgtttcttc tttagaaaca agccctgcga tttgacctgc cataacagag ccaccatcca
    24961 catcaccgtg aacaactgct ttggctagag cacctgctcc catttgttca aagatttcta
    25021 aatcaggatc ttcttgctta aaggcatctt tttcagccag ttcaaaatct ctagtcaact
    25081 gatttttaat agcacgaaca gcatgaccaa agtgctgagc tgaaatcgta gtatcaatat
    25141 cccttgcttt taaaattttc tccttgtagt ttggatgggc attcgactct tttgcaacta
    25201 caaaccgtgt ccccacctgt acagcctctg cacctagcat aaagccagcc gcagcacctt
    25261 caccatccgc aattcctcct gcagcaataa caggaataga tacagctgtg gctacctgtc
    25321 gcaccaaagt catggttgtt aatttaccga tatgcccccc agcttccatt ccttctgcaa
    25381 taacagcgtc tgcaccgatt ttttccatgc gtttagctaa agcaacacta ggaacgacag
    25441 gaataacgat tatcccagct tcatggaaac gttccatata cttgcttgga tttcctgctc
    25501 ctgttgtgac aactttaaca ccttcttcaa taacgagatc cacgatatct tccacaaagg
    25561 gagataagag catgatgttg accccaaagg gtttatcagt caatgatttg attttatcaa
    25621 tattggcctt gacaacttct ttcggggcat ttcccccacc gataattcct aatcctccag
    25681 ccttggaaac agcccctgcc aaatcaccat cagcaaccca ggccatccct ccttggaaaa
    25741 taggatagtc aatcttcaat aattctgtaa tacgcgtttt catagtgcct ccaaccttcc
    25801 ttgcttacgt aatagttcga tttcaccata atttgacagt caaactatta cctaaacaag
    25861 agggagtggg tttctcccta ctccttctac ttaatattct gcttattttg cttgctcttc
    25921 aacgtaagca accaagtcac caactgtttt caagtcattt tctgcttcga tttggatatc
    25981 aaaagcatct tcgatttctg agattacttg gaacaagtcc aatgaatctg cgtccaaatc
    26041 atcaaaagtt gattcaagtg ttacttctga tgcgtctttt ccaagttctt caacgataat
    26101 ttcttgtact ttttcaaata ctgccatgat aggactcctt taaaataaat agttttttta
    26161 taacaatgtg ttcaccacat gattacctaa attgtaagaa tgagcgtgcc ccaggtcaaa
    26221 cctccaccga agcctgatag aagaacagtc tggctaccat ctaaagggat gagaccttgt
    26281 tctacacact ctgaaagtaa aatcgggata ctggctgcac tggtattgcc atattccatc
    26341 atattggctg gaagtttggc tcggtcaaca ccaatttttc tagccatctt atccaaaata
    26401 cggtcattgg cttgatgaag tagcagataa tccaagtctg tcacctctat aggagattca
    26461 tcaatagtct gcttgataga cttggctaca tctcgaatgg caaaatcaaa gactgtgcgt
    26521 ccatccatct tcaaaaatga atctgcactt tcttgatctg aaaatggaga atgcaaacct
    26581 gaatgcccat aagttaaaca ctcgctgcga cttccatcgc tattgagact ctcagctaag
    26641 aaatgctctt gctcgctagc ttctaacaag acaccaccag caccatctcc aaacaacaca
    26701 gctgttgatc gatccgacca atcgactgcc ttagagaggg tttcactacc aatcaccaag
    26761 cctttttgaa agcgaccaga agcgataaac ttttcagcag ttgaaagagc aaatacaaat
    26821 ccactgcaag ccgcggttaa gtcaaaagca aaggctttat tagcaccaat attagcttga
    26881 acacgagcag ctgtagaggg catcatcgaa tctggagtaa tggtagctag gatgataaaa
    26941 tccagttctt ttcctgttat tccagctttt gccatcagtt tcttagcaac ctctgtagcc
    27001 aaatcactgg tagattctgt tcttgaaata tgcctttgtc gtattcccgt tcgacttgaa
    27061 atccactcat cattggtatc cataatctga gccaagtcgt gatttgtaac cacttgctct
    27121 ggcacataat gagcaacctg acttattttt gcaaaagcca ttatttcaaa tcctccaaaa
    27181 attggtaaag attagtcaag cctttaccca tgacagcaat ttcttcctcg ctcatgccat
    27241 caataatttt ttctaccatg gccttgtgga agcgtttatg cagtctatga atcaagcgac
    27301 ccttctttgt caaatgcaga tgcaccacac gacgatcctg ttctgaccga actcgctcaa
    27361 tgtagccctt acgctctaaa ttgttcaaac ttgtcgtaac agttccaaga gttaccatca
    27421 actcttttga cacttgactt ggagtcacat ctggagcctt accgatgaca tcaatcgtat
    27481 gcatttcttt gatggagata tccttaaaac gactacctct caagttcact tcctcaatta
    27541 caaggacatt gttaaatata gatgttaaat attcattgat tcgttggtag tccatttttc
    27601 atatccctcc ttcttcaaaa aacttttaca atcaaaacat ttgacagaaa gaattatatc
    27661 aaaattcaaa gaatgatgca agtatttttt attttcctgt aaatttaggt cttcttctct
    27721 ccgaatgagc tcgcactcct tctttgaaat cctctgtttg agctaaggat ttctgtaggt
    27781 tcagttctaa agtagcgtaa ccctgccagt ctttaaattg gctctcccaa accaacttct
    27841 taatggcagc ataggaatta cttgaagcac gtcttaattt tttaagaagc tgttctctcg
    27901 tcttttcaag tttttcagct tcagaaacgc ggtaaaccaa cccccattct agggcttttt
    27961 ctgccgttaa agcctctcct gtcatagcta attgagcagc acgcgtcaca ccgatactgc
    28021 ggctcaagag atgaattccc cctgcatctg gagccaaacc aacaccaaca aaggcttgga
    28081 taaacttagc cttatccgtc gccaaacaga aatctgccgc aacagccata ttcgctgcgg
    28141 cacctgcaac agcaccgtca acttccatta aaacaggttt ggctatttgc ttgattttat
    28201 aagaaatcgt attgaccaac tctgcgattt ttgtcaatga tggaatatca tcctcatcca
    28261 ctgcccgctt catctctacc aaatctcccc caactgagaa gacctttcca ttggcattga
    28321 ttaagataaa atgcacagct ggattttctt ctgccaaagt cagagcttct aaaatctcct
    28381 cacacatggg aatatgaaaa ccatttgcga cctcaggacg gttcaaggta aggattgcca
    28441 agtcctcttc aagctgataa ataatgtgtt ccatcagggc tcctttttat tttataagca
    28501 gtttatactc ttcgaaaatc tcttcaaacc gcgtcagctt ccatctgtaa cctcaaaaca
    28561 gtattttgag ctgacttcgt cagtcttatt tacaacctca aagcagtgct ttgagcagtc
    28621 tgcggctagc ttcctagttt gctctttgat tttcattgag tgttaaatta tttcactgtc
    28681 aaagtatatc ttttttagga gcagaaagca agaaaaaatc gactgaaagt gtctcagccg
    28741 ataagaaagg ctcgctttag gctagaaagc atcttatttt cttcattgaa aaaagccttt
    28801 ctttctgcta taatcgtata aaatacttac tttaggagtt cttatgaaag ttgttaaatt
    28861 tggaggtagt tctcttgcct ctgctagtca attagaaaaa gttttaaaca tcgtcaaaag
    28921 cgattcagag cgtcgttttg tagtcgtttc tgcgcctggt aaacgcaatg ctgaagatac
    28981 taaggttacg gatgccctga ttaaatacta ccgcgactat gttgcgggta acgatattag
    29041 caagagccaa agctggatta tcgaccgcta tgctgctatg gttagtgaat tgggactaaa
    29101 accagctgtg ctagaaaaaa tttctaaaag cattcacgcc ttggccactc ttcctattga
    29161 agaaaatgaa tttctctacg atactttcct agcagccggt gaaaataaca atgccaaatt
    29221 gattgctgcc tactttaacc aaaatggtat cgatgcacgc tatatgcacc ctagagaagc
    29281 tgggattgtg gtcacaagtg aacctggtca cgctcgcatc attccatcaa gttatgacaa
    29341 gattgaagaa ttgacaaaca ccaatgaagt ccttgtcatt cctggtttct ttggtgtcac
    29401 taaggaaaat caaatctgta ctttctcacg tggaggatct gatattacag gttctatcat
    29461 tgctgctggt gtcaaagctg acctctatga aaactttacg gacgttgatg gtatctttgc
    29521 agcccaccct ggtattatcc accaaccaca ctcgattcct gagttgacct accgtgaaat
    29581 gcgcgagttg gcctatgcag gcttctcagt ccttcatgac gaggctcttc ttcctgccta
    29641 ccgtggaaaa attcctctgg ttatcaagaa taccaacaac cctgaccatc caggtactcg
    29701 tatcgttcta aaacacagta atgatgaatt tccagttgtg ggaattgctg gtgactcagg
    29761 ctttgtcagc attaatatgt cgaaatacct catgaaccgt gagattggat ttggccgcaa
    29821 ggttctgcaa atcctggaag aacttaacat cggttgggaa catatgccaa caggtatcga
    29881 cgatctttct atcattctcc gttctcgcca actaactccc atcaaggaag aagaaatcct
    29941 gcgtcagttg gttcaaaagg ctaaagtaga tcatgcagaa atcgaacacg acctttctat
    30001 cattatgatt gttggtgaaa aaatgaagag ccatatcgga gtgactgcta ctgcgacacg
    30061 cgctctatct gaaaacaaaa tcaacatcca gatgatgtct caaggttcta gtgaagtttc
    30121 tattatgttt gttgtcaata aagaccaaga gaaagcagca attaaagccc tctactatgc
    30181 cttttttgga gaaagtaagg aagactaagc atggctcaat cacttaacaa aacagtactc
    30241 ctcagtacga caggcacttc ctacctctct atcgctggga aagttgggaa attccttgtc
    30301 ggagatcagg ctttggaatt ttacccagat gtcaatgtcg aacaatttat ccagattcct
    30361 tggagccata tcaatcagat tggagccaat gtcactggac gcaaagtcag ccgccacttc
    30421 gaagtcttta cagacaaagg aaaattcctc tttgcttcaa aagactcagg tgccattctc
    30481 aaaattgcac gcgaaaaact aggcaatgac aaggtcgtca aacttccgac cctgattcag
    30541 acaattagcc aaaaatttaa aaatctattt gcaaaaaagt agaaacttta gtataatcat
    30601 agcaacggat aagtaggtta tcttcttctt tcagaaagtc tgcgggtact gcgagcagat
    30661 aggggggata ggtgaaattc taccgttagt aacaattaca tacacaatca agtgcacacc
    30721 tgtgaagttg gatggaaccg tggccctgcc actccaacgt tttgtcaggc gtgctttttt
    30781 cataaaggag ttcttatgtt agatatcaaa cgtattcgta cagattttga agctgtcgca
    30841 gaaaaattag ctacacgtgg tgtagatgct gctgtcttga atgaaatgaa agaaatcgat
    30901 gctaaacgtc gtaacatctt ggtcaaggtt gaaactctca aagcagaacg taacacagtt
    30961 tctgctgaga ttgcccaagc taagcgcaac aaggaaaata cagatgacaa gattgctgcc
    31021 atgcaaaatc tatctgctga ggttaaagcc ttggatgctg aattggcaga aatcgatgct
    31081 aaattgacag aatttacaac gactcttcca aatatcccag ctgacagcgt tcctgttggg
    31141 actgacgaag acgacaatgt ggaagttcgc cgttggggta ctccacgcga gtttgacttc
    31201 gaacctaaag ctcactggga tctcggtgaa gaccttggta tccttgactg ggaacgcggt
    31261 ggtaaggtaa caggcgctcg cttcctcttc tataaaggcc tcggtgctcg tttggaacgt
    31321 gctatctaca actttatgtt ggatgaacat ggaaaagaag gctatactga agtcatcaca
    31381 ccttacatag tcaaccatga ttctatgttt ggtactggtc agtatccaaa atttaaggaa
    31441 gatacttttg aactcagcga taccaacttt gtcttgattc caactgctga agttcctctg
    31501 acaaactact accgtgatga aatcttagac ggcaaagatc ttccaatcta cttcactgcc
    31561 atgagtccgt cattccgttc tgaggctggt tctgccggtc gtgatacgcg tggcttgatc
    31621 cgtttgcacc aattccacaa ggttgaaatg gtcaaatttg ccaaaccaga agaatcttac
    31681 gaagaattgg aaaaaatgac agccaacgct gaaaacattc ttcaaaaact caaccttcca
    31741 taccgtgtcg ttgctctctc tactggagat atgggcttct cagctgcgaa gacttacgac
    31801 ttggaagtgt ggattccagc acaaaacaat taccgtgaaa tctcaagctg ttcaaacaca
    31861 gaagatttcc aagcccgtcg tgcccaaatc cgttaccgtg atgaagcaga tggcaaggtg
    31921 aaactccttc ataccttgaa cggttctgga cttgcagttg gacgtacagt ggctgcaatt
    31981 cttgaaaatt accaaaatga agatggttct gtgaccatcc cagaagcact tcgtccatac
    32041 atgggtggag ctgaagtcat caaaccataa aaaataaggt ttagctattt ctagctagac
    32101 cttttttcgt aaccaaatca gataagcacc tagtacaaag aataaaatag ttaggcatat
    32161 aatggtttca gccaatacca ggtaatccag aaatggaagt ttcaaaattc cctgagccat
    32221 cttgagcgag gtcgctgtga taatggttgg gaaggtgagg gctgagaagg ctggttgaaa
    32281 accttgtttt aaaatgttgg gcagacgagt taaaacaaag aaaaagaagg attgagaagc
    32341 caaaatcatg acaatcaaga cccaagtcgg caggctggtt cctcctactc gaactagaga
    32401 agccaagagt agagagaaag gagcacagta gattccttct tgtccaagca aggctagtgg
    32461 gagtggatgt ttctttaaat cgctataaat aaggggatag agatagaagg tcaagagaaa
    32521 accaaaactc aaggtcgcat aggcaatttc gataatacct accagaggat aggtcaaggc
    32581 agccactgct atccccacat agagaaccgt ccagcttgga gtggcatgaa ccctccgccc
    32641 tggacaagca aacttgatgg taaaaccagc aatcaaggtc aaatccaaga gaaatgaaaa
    32701 ccaccaaatc ccttgtgcta ccaaaggaag ataagagaat acgcgaaaga cataggtcga
    32761 taaaatcatc ccagccatag gaaaggttgc cattcctgac aaaagagggg gcttggtcaa
    32821 ttcttgcttg gtttctttcc aattaaagag atgcagaatt agaaagtaaa tccataaaac
    32881 caaaccagtc agactaaaaa gatgggatag aaccggcaac gtatctaaaa taagatttcc
    32941 agctcctgcc aaacctagca aacaacctga aaatactaag gggagttttt tcatcctaac
    33001 ctccaataat catgttagtt tcagtataac ataaaagcgc ttaaatgagg atttaaaaaa
    33061 acgaagtccg attatttcag acttcatttt actcagatat gaattaggca taaggttgca
    33121 attctggatt aattggtgta ttagctaagt tgttggcata gttacagagg attgctaggc
    33181 tgacaccaaa aaccacatcc aaggcatttt gttgagtgta gccagcttct aaaaactcag
    33241 acaaggcttc atctcctaca cgacccttgg tattgataac tgccaaggta aacttagcta
    33301 gggtatccaa tttaggatct gtttcaattg gagtacgatt gcgaagagct tgaatcaagt
    33361 catcattcat ctggatttgt ttgatggaaa aggctgtgtg acctgcgaca cagaaggcac
    33421 aaccattggt cacggctgcc gtgatttgca ccacttcacg ctcaacgggt gtcaggctgt
    33481 tgcgacggtg gatagatgag acaatttggt aggcttctaa aacagtcggg gcattggcca
    33541 agagaccgat taggttggga atatagccat tgttgtcttt ttctactgtt tcaagaattt
    33601 ctttcacttc tgctggtgct gactctactg tatggatagt aaatgttgtc ataagatacc
    33661 tcttttctta ttattgacac taatattatt ggaaaatctt ataaaatcct gattcctaag
    33721 tttatctaag ataaagcttt attctctcat aagattttcg ttgttatatt agtttatcac
    33781 acttccaatc acttgcataa tatatattat atatcaggct gataaaaatt atttataggc
    33841 aaaaaaatca cacgagctgt gtgattccat tatttgttaa aatacttttt agtttcagca
    33901 ataacgactg gcgacaagac caagagggca atcaagtttg gcagagccat caaggcgtta
    33961 acgatatctg cgataatcca gaccatatcc aactcgataa atcctcctaa caagaccatg
    34021 agcacaaaaa acacacggta gagccagata aagcgagccc caaagaggaa ctcaaaacag
    34081 cgttctccgt aatagttcca acctagaatc gttgtaaagg caaaaagtac aaggaagatg
    34141 gtcaagaggg caggcccaaa gtgtgaaaag actgttgaga aagctgactg agtcaaggca
    34201 accccattca agtcaccact ccaaactcca gttaccaaga tggtcaaacc agttagagta
    34261 caaatgatga gggtatcaat aaaggttcct gtcatggaaa tcaaaccttg ctctactggt
    34321 tcatttgtct tggcagctgc aataggagca gaacccagac cagattcgtt tgagaacaca
    34381 ccacgcgcca caccattttg aatagccatc cgaacgctag caccagcaaa tccacctacc
    34441 gcagcaaggg gactaaaagc tgaggtaaag actaaagcga ttgtgccagg gatttttccg
    34501 atattaaaga aaataactgt aagagttcct aagatataaa tgagggccat aaaaggaaca
    34561 acagtagttg aaaccttaga aatagacttg agtccaccaa agactgcaat cgctacaaag
    34621 acagacaaga cgagagctgt gatggctggc gaaatcgtcg ttgtattttg gatagattct
    34681 gtaatcgagt tgacttgggt gaaggttccg attcccaaga gagcaaccaa tactcctgct
    34741 actgcaaaca aaacagcaag tggtcgccac ttttctccca tccctagaag gatatagtgc
    34801 atgggacctc ccgctactgc accatggtcg tccttggtgc ggtatttgat ggccaagagt
    34861 ccttccgcat acttggtagc cattccaaag aaagccgcca tccacatcca aaatagagct
    34921 cctggtccac caaccttgat agccgtcgca actcctatga tatttcctgt tccaacagtt
    34981 gatgccaagg ctgtacacag agctgcaaaa ctggatacat caccatgtcc cttatcctgg
    35041 ataaaaataa gctgaaaggc cttgggcaga cgcaaaacct gcaagagtcc tagccgcatg
    35101 gttaggtaaa tccctgttcc gaccaataaa atcaagaggg gcggtcccca agcaaaagca
    35161 tcgattgatt taagcaattc taacatttcc ttctcctatc gtttcaaccc caaaagaaag
    35221 agcacatgca agatacatgt actctggaat gcttagataa atgctaaaaa gcggtctatc
    35281 ctagctctgt ccttttacct gagagtttga gcagttgcct gccttgcccc ttcggtgcct
    35341 ttacggtctc tccagagttc cgtccattta cagtcatgga aaatcaaacg attccccact
    35401 tctattaaac ttcattcggt gttggtattt aattgattct aattttacaa aaaatgttgg
    35461 cttttgtcaa tgtgtttatt agtaaaaatt agttcaacag tttttacttt ataaagtcca
    35521 gaatactgct atcctttaaa agtgacaata gtcgcaccac tgcctccagc attttgtggg
    35581 gcatagccga aactcttgac atgtttgttt ctttgcaagt atttggtaac tccttcacgg
    35641 atgactcctg ttccgatacc atggatgata tcaacttgag ccatattgtt aagcaaggct
    35701 tggtcgatga aggtatctag ctcattcatg gcttctacat agcgcttgcc tcgaagatcc
    35761 agtctagctt gaggtcctcg cccagaagtt cgtttcacaa cattgacctg tttcttcttg
    35821 actggttttt cttgctgggc ttgaacaaga tcaaactctt tctcttccaa ggtcatctta
    35881 atcaagccaa cttgggcttc ccagcgaccg tccttgagtt gactggtcaa ggtaccacgc
    35941 tgaccataac tgagaaccac gatatcatct cccacctttg gagctcgttt tttcttggcc
    36001 ttttgaagga ccttattttt agacaagtcc actttttcag gagccaattt tttcaacttg
    36061 accttggctt caatgatttc gtggggcttg agttgggatt tactgtggag atttttgaga
    36121 atctggtcac tttcacttaa ggccatatcc acaatctcag cagcctgttc acgcgccttg
    36181 ttaagctcgg tttccttttc acgattaagc tcgttgtaga gtttttttag cgcacggttc
    36241 atcttgagat tttcttgctc cacctcacgg atattgtcca aacgtttgcg gctttccagc
    36301 gtctgctctt ctaattgctc aatgatacga ttgacgtcat tgtcctgatc gatctgctga
    36361 ctggcatctc ctacgataac ttcagatagg cctagacgtt tggcaatttc aaaggcatta
    36421 cttcggccag gaacaccctg cataaagcga taggtcgggc gaagagttgc agtatcaaac
    36481 tccatactgg cattttgcac aaaggctgtc tcaataccgt aggccttgag ttctggatag
    36541 tgggtcgtcg ccatggtctt gatttgacgc aggcgaaggt cctccagaat agccatggca
    36601 agggctgctc cctcttgggg atcagtacca gcccccaact catccaaaag taagagtgaa
    36661 tgttggttga ccttgccaag aatatccacg atattggtca tatggctaga gaaggtagac
    36721 aagctctgct caatagactg ctcatctcca atatcagcaa agatttcttc aaaaatacca
    36781 acacgacttc ccttgtctgc taaaatcggc aatcctgact gggccatgac ctgtgtcaag
    36841 cccagagttt tgagcatgat ggtcttccca cctgtattgg gacctgtaat gacaatagct
    36901 gttaaatctt gaccaaaata gacatcattt gcgacggcat ttttgaccaa aggatggcag
    36961 acatggagca gttgaatctc ttgattttct gacagctgag gcacgactgc ttgtctttct
    37021 tggataaatc gaaccttggc acgaatcaag tccagatgac cgataatcca agcgtcatta
    37081 gcaatctcag ccgcatgagg gcggacacgc tcagaaattt cttggagaat gcgaagcatt
    37141 tcatagcgct catctgctcg cagactagca atttcttcgc tcagtttgac tacctcacgt
    37201 ggttcgatat agacggtgtt tccactagca gaaatatcat gaacgacacc tgcaatctta
    37261 ttgcggtagg tgtttttgac tggtaaaacc tgacggccat ttctgctagc aacaattcct
    37321 tccgtcaaca tctgcgcttt ttgcttgagc aagtcttgta aaacatcgcg tacctgactc
    37381 tcgctatcat gtatttttcg acggattcgc gccaattctt cactggcaaa attttcaatg
    37441 aaacccgcat cattaaaggc ctgaagattt ccttgtaatt gcggaaaatc atgtaatttc
    37501 tcaaaccaaa gggctaattc ttccaagctg acattttcca gattggcgta aaaactttga
    37561 agttctcggc tggtaagaag cacgcgtttc aagagtagga actcctcgat attgagatcc
    37621 gctcccatct ccaacctctt gcagactcct gcaatttcct tagttgagag aatagtaaaa
    37681 tgcggttgct cgacgaaaag agcctgcatt tctttcatct cagcaaaagc ctgtttgatt
    37741 ttatctgctt tggcagtcgg agccagctgt ctcaattgct ccaagccctg ctcggtcaac
    37801 aaatgaggct caaacaaggc cttgacctta tcgagctcta atgtttctaa tattttctta
    37861 ttcatcttta tttccttgtc tttgaatgtc taggtgtggt agctttttac attctgatag
    37921 attcgagtca aatctgtaaa caaagggcta ggaaaactcc tgcccttttt atccgattaa
    37981 atttgtcacc cagatttgtt tgagccaact ggttgttatc ggtatactct ggatgatgtg
    38041 ttttgcgacg atactctttt caagaggatt ttgtataact gccatgggga tggtcgccaa
    38101 gattgtcaag gccatttgca agacaaataa ggtcaccaac atggacaaga tacctgctga
    38161 aacttggaac aacttaccac ccagtttttt gctaggaatc aagtgtaaga gaagaccaag
    38221 caaacgacca atgctataga caatcccaaa tacaagcaag tagccgatac ctgcataaaa
    38281 gaccttatcc agctgaaaga gttgatccga tgggaaaaag aaagtcccct gaccttcctg
    38341 cgaatttgca taagggagca ataaatggaa ttgctctcca agccccttat aaaactggcc
    38401 agccataaaa gccgatgcca tggctgaaat caggtaataa acctgtaaga gcaggcctct
    38461 ccgatagccg atataaaatc cccaaaccaa gaccaataga agaaggaatg aaatcataag
    38521 gaatcctcaa tcttgctctg ttcttgctta caagtcacaa gcttgtgacg gagttcttct
    38581 agctcttgct ccttatcgtc aaattcaatc tcacggctga gctgagttga taaacagttg
    38641 actgccaaca aaagagcgat tgtttcatca tctgcgctag gcatttgttc tttaattgct
    38701 tggtattttt ctgtcgcaac cttagcgatt tcctccataa aaaggttatc atgttcgctt
    38761 gtcaaggtta acgatttttt cccgaatgta aatttgaatc gatttagatt tgccataaaa
    38821 ttcacctcac gatattatac caaaattcgc taattttgtc agtttttaca aattttactg
    38881 cttttgtggt acaatagaaa ctatggcaag tatcacactc acaccaagcg aaaaggatat
    38941 tcaggctttt cttgaacact atcaaaccag tctggctcct agcaagaatc cctatatccg
    39001 ctactttttg aaactacctc aagcaacggt ttctatctat acttctggaa aaatcttgct
    39061 tcagggtgaa ggggctgaaa aatacgccag tttctttgac tatcaagctg tagagcaaac
    39121 cagcggacaa aatcttcctt taattgggac agatgaggtg ggaaatggtt cctactttgg
    39181 tgggcttgca gttgtggctg cctttgtcac acctgaccag cacgactttt tacgaaaact
    39241 cggtgtgggg gattctaaga ctctgaccga ccaaaagatc cgtcagattg ctcctattct
    39301 caaggaaaaa atccagcacc aggcactcct tctctcaccc agcaagtaca acgaggtcat
    39361 cggagaccgc tacaatgctg tttcggttaa ggttgccctc cataatcagg ctatctatct
    39421 cctccttcaa aaaggtgttc agcctgagaa aattgtgatt gatgccttta ccagtgctaa
    39481 aaattatgac aagtacttgg cacaagaggc caatcgtttc agcaatccta tcagcttaga
    39541 agaaaaggct gagggcaaat acttggctgt cgcagtttct tctgtcattg cgcgtgatct
    39601 ctttctggaa aatcttgaaa atttgggacg agaactgggt tatcagcttc caagtggagc
    39661 tggaacggct tctgacaagg tggctagcca gattttgcaa gcctatggta tgcagggact
    39721 caacttctgc gccaaattgc actttaaaaa cactgaaaaa gcgaaaaaac gcttagaaag
    39781 gtaagttatg aattcactta aaaatttctt aaaagagtgg ggattgttcc tcctaattct
    39841 gtcattacta gctttaagtc gtatcttttt ttggagcaat gttcgcgtag aaggacattc
    39901 catggatccg accctagcgg atggcgaaat tctcttcgtt gttaagctcc tccctattga
    39961 ccgttttgat atcgtggtgg cccatgagga agatggcaat aaggacattg tcaaacgtgt
    40021 catcggaatg cctggcgata ccattcgtta cgaaaatgat aaactttaca tcaatgacaa
    40081 agaaacggac gagccttatc tagcagacta tatcaaacgc ttcaaggatg acaaactcca
    40141 aagcacttac tcaggcaagg gctttgaagg aaataaagga actttcttta gaagtatcgc
    40201 tcaaaaagcc caagccttca cagttgatgt caactacaac accaacttta gctttactgt
    40261 tccagaagga gaataccttc tcctcggaga tgaccgcttg gtttcgagcg acagccgcca
    40321 cgtaggtacc ttcaaagcaa aagatatcac aggggaagct aaattccgct tctggccaat
    40381 cacccgtatc ggaacatttt aagagaccta agaggccgag aatcacaaat ctcagcctct
    40441 tcttctatcg tgagaagtga ttgtttattg acaaatactc aatgaaaatc aaagaacaaa
    40501 ctaggaagct agccgtaggc tgcttaaaac agtggtttga ggttgtggat agaactgacg
    40561 aagtcagctc aaaatactgt tttgaggttg cagatggaag ctgacgtggt ttgaagatat
    40621 tttcgaagag tataaaataa aaacaatccc aactctcacc tattcatgca aaggaatttt
    40681 atggaagttt atttttcagg aaccattgaa cggattattt ttgaaaatcc cagcaatttt
    40741 tatcgcatcc tcctcctaga aatcgacgat acggacgcag aggattttga tgattttgaa
    40801 atcattgtca caggaaccat ggctgatgta attgagggcg aagactatac tttttggggg
    40861 caaattgtcc agcactccaa gtatggagaa caactgcaaa tcagtcgtta tgatcgcgca
    40921 aaaccaacta gtaagggatt ggtcaagtac ttttcaagta gccatttcaa ggggattggt
    40981 ctcaagacag ctcagaaaat cgtagatacc tatggcgaaa ataccattga tgaaattttg
    41041 caacacccag aaaagttaga aggcatcgca ggactctctg ccaaaaatcg cgaggctttc
    41101 gtctccactc tccgtctcaa ctacggaacg gagatggttt tggccaaact agccaactac
    41161 ggcattccca acaaactagc ctttcagatt caagactttt acaaggaaga aacccttgat
    41221 gtggttgaaa attatcccta ccagctggtt gaggatatca agggtttggg ctttacaatt
    41281 gctgaccaac tagctgagga actaggcatc gaaagtcagg ctcctgaacg cttccgcgcc
    41341 ggtctagttc acagtctttt tcaggcctgt atggaaacag gagacaccta tgttgaagca
    41401 cgggatttgc tggaacaaac ccttactctc cttgagtctt cccgtcccgt agaactagac
    41461 cccagccaag ttgcccaaga gctctcctac ctgatcgaag aagacaaggt tcagcagatt
    41521 gataccaaga tctttgacaa cagcctcttt ttcgctgagg aaggtatccg cagtcacttg
    41581 attcgtatcc ttgaaaaagg agaacagaag agacaagatt tagaaactat tcaaaagcat
    41641 atcactactg tcgagcaaga actggggatt gagtatgata acattcaaaa acaagctatt
    41701 tgtgacgcta tccagaacaa ggtctttatc ctgacaggtg ggcctggtac tggtaagaca
    41761 actgttatca atggaatcat cgctgtttat gcccttttag aaggacttga cttcaggaag
    41821 aaaagcaatc tgcccattct tcttgctgct ccaactggtc gagctgctcg tcgcatgaat
    41881 gaattgacag gtttgcctag cgcgaccata catcgccact tgggaatgac aggtgacgat
    41941 gataccagtc atctggaaga ttacctagat gctgacttta tcatcgtgga tgaattctct
    42001 atggtagata cttggctgac caatcaactc ttctccaata tctcttctaa cagtaagatc
    42061 ctcatcgtag gtgacagtga tcagctacct tctgtcagtc ctggacaggt tctagcggat
    42121 ctgcttcata ttcctttgat tcctcagact cgcttggaaa aaatttatcg acaaagcaaa
    42181 gaatcaacca tcgtcaccct agctagtcag attcgacagg gcatcttgcc agctgatttc
    42241 acccaaaaaa aagctgaccg ttcctacttt gaaattgcta gtggccatat tcctgccacc
    42301 attgaaaaaa tcttaggtgt cgccctcaga aatggtattc ctgcccgtga tatccaagtt
    42361 ctggctccta tgtaccgagg gacggcaggg attgatgcta tcaatcagct catgcaagac
    42421 ctgctcaatc ccccacaaaa agatcaactc agttttgaag ctcctcagtg ccactatcgt
    42481 aagagagaca aggtcattca tttggttaac gatgctgaaa tcaatgtctt taatggggat
    42541 ttaggagcta tcacagacct gattcctggt aaatacaccg aatcgaaaca agacgagatt
    42601 gtcattgatt ttgatggtaa tgaagtctct tacccccgta acgaatggta caagattcgc
    42661 ttggcctatg ccatgagtat tcataagtct cagggaagtg agttcccagt tgtcatccta
    42721 ccgattacta gtgctagccg acgtatgctg gagcgaaatc tcatctacac agccattaca
    42781 cgtgccaaaa gcaaactcat cttactaggc gaattacaag ccttcgacta tgctacccaa
    42841 cacatcggaa ctgcccgaaa aacctatctg attgaacgct tcagtgatct actggagaat
    42901 gttgaagaaa agcaacaagc tgtctctgaa acagtcacat caagtgcctc tgaacaatcc
    42961 tacatcctaa ccgaagaaaa ctgggacagc attccagcca tgattgggat tacagacaca
    43021 gacctcaaag agatttttgg aaaatagtac atcagaaaac ccaccaattc aggtgggttt
    43081 tctgtttatt aagattattt tactgttgct gtgcttgtga tcaattcaac agcttttttg
    43141 atagtgatat catgtttcaa catgtcagct gaaagcaagt tttgaacttg tgcaacttcc
    43201 atgttgtagt ctgctgccaa ttgctcaact tctttttgga tttcttcttc tgaagcatca
    43261 aatccttcag ctttggcaac tgcttcgata acaaggttag tcttagtacg tgactcagct
    43321 tctgcttggt attggttgtg aaggtcttct tgagtagttc cagtgatttg gaagtacatg
    43381 tcagggttga tcccttgacg ttgcaagttc ccaaggaatt catttactga acggtgaact
    43441 tcttcatgga tcatttcttc tggaagttct acgatttcag cgttttctac agctgtatca
    43501 attgctgcac cttcaactgc atctttgtaa gcttcttctt tagcagcagc caattctttg
    43561 cggtattttt ctttcaagtc agcaagtgtt tcaacttctt catcaatgtc ttttgcaagt
    43621 tcatcgtcaa gagctggaac ttctttagct tttacttcgt ggatagttgt cacgaattta
    43681 gcttctttac ctgcaaggtc ttctgcttgg tagtcttctg ggaatgttac gataacatca
    43741 acggtttcgc cagctgagtg acctaccaat tggtcttcga aaccagggat gaattgacct
    43801 gaaccaagtc caagtgagaa gttttcacct tttccaccgt caaattcaac accgtcgata
    43861 gaaccaacga agtcgatcac aacagtgtcg ccgttttcag cagcagcttc cttgataacc
    43921 aattcagcca gattgttgcg ttcgcgttcg atacgctctt caacatcagc gtcagttact
    43981 tctttttcta catcaactga tacttcaagg tttttgtagt cacccaattt tacttcaggt
    44041 tttgtaacga cttcagcagc gataacccag tcttgacctt tttccattga agttacgtca
    44101 atttttggtt gggcaaccac ttcaagacca gcttctttta cagctgcttc ataagcgttt
    44161 ggcaaaagag cgttcataac gtcttggtaa agtgattctt caccaaattt tttgtcgaag
    44221 ataggacgtg gaaggtgacc tttacggaaa cctggaacat taagagattt cttcactgac
    44281 ttgaagacac ggtccaattc tggtttgatt tggtcttgag agatagtgaa agtcaagaca
    44341 ccacggtttg tttctttgtt ttcaaatgat acagacattc tgtcatttct ccttaaaatt
    44401 ttttaaatac agtctattat aacattttct ataaataaaa tctagactaa tgcagccaat
    44461 tatagacaac aagccttttt cctaactaaa acactcataa agtatagaca attttagact
    44521 actttggata tcttttggtt agtcattttc caaaactaat ttatctaatt tttcagt
//
LOCUS       DAVHLA010000011        41116 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVHLA010000011 DAVHLA010000000
VERSION     DAVHLA010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41116
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.011"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            163..417
                     /gene="blpM"
                     /locus_tag="VVO77_000734"
     CDS             163..417
                     /gene="blpM"
                     /locus_tag="VVO77_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HEU5692784.1"
                     /translation="MDTKIMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVDLWAGVTGATGGF"
     gene            433..636
                     /gene="blpN"
                     /locus_tag="VVO77_000735"
     CDS             433..636
                     /gene="blpN"
                     /locus_tag="VVO77_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HEU5692785.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGRLLGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            880..1029
                     /gene="blpO"
                     /locus_tag="VVO77_000736"
     CDS             880..1029
                     /gene="blpO"
                     /locus_tag="VVO77_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HEU5692786.1"
                     /translation="MDTKMMSQFAVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            1845..3998
                     /locus_tag="VVO77_000737"
     CDS             1845..3998
                     /locus_tag="VVO77_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEU5692787.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLFSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNSLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGSVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLIALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            4011..5360
                     /locus_tag="VVO77_000738"
     CDS             4011..5360
                     /locus_tag="VVO77_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEU5692788.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQSEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQFFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            5530..6237
                     /locus_tag="VVO77_000739"
     CDS             5530..6237
                     /locus_tag="VVO77_000739"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEU5692789.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIVG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            6439..10164
                     /locus_tag="VVO77_000740"
     CDS             6439..10164
                     /locus_tag="VVO77_000740"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEU5692790.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFTQFEAIQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKVG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVCVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEAANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            10257..11699
                     /locus_tag="VVO77_000741"
     CDS             10257..11699
                     /locus_tag="VVO77_000741"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEU5692791.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDSLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            11736..12758
                     /locus_tag="VVO77_000742"
     CDS             11736..12758
                     /locus_tag="VVO77_000742"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEU5692792.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            12755..13300
                     /gene="purN"
                     /locus_tag="VVO77_000743"
     CDS             12755..13300
                     /gene="purN"
                     /locus_tag="VVO77_000743"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEU5692793.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            13384..13893
                     /locus_tag="VVO77_000744"
     CDS             13384..13893
                     /locus_tag="VVO77_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEU5692794.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            13918..15465
                     /gene="purH"
                     /locus_tag="VVO77_000745"
     CDS             13918..15465
                     /gene="purH"
                     /locus_tag="VVO77_000745"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEU5692795.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDATYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            15587..16849
                     /gene="purD"
                     /locus_tag="VVO77_000746"
     CDS             15587..16849
                     /gene="purD"
                     /locus_tag="VVO77_000746"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEU5692796.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKTFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            17040..17531
                     /gene="purE"
                     /locus_tag="VVO77_000747"
     CDS             17040..17531
                     /gene="purE"
                     /locus_tag="VVO77_000747"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEU5692797.1"
                     /translation="MTKPIISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTP
                     DLMFKHAEEAYSRGIKVIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYS
                     IVQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSN
                     ELI"
     gene            17518..18609
                     /gene="purK"
                     /locus_tag="VVO77_000748"
     CDS             17518..18609
                     /gene="purK"
                     /locus_tag="VVO77_000748"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEU5692798.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPVSRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEVD
                     LEAAYALAESADCVLEEFVNFALEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLVDKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEKYVAENPSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            18619..18846
                     /locus_tag="VVO77_000749"
     CDS             18619..18846
                     /locus_tag="VVO77_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEU5692799.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIGKEEFE"
     gene            18909..20207
                     /gene="purB"
                     /locus_tag="VVO77_000750"
     CDS             18909..20207
                     /gene="purB"
                     /locus_tag="VVO77_000750"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEU5692800.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(20262..24200)
                     /gene="strH"
                     /locus_tag="VVO77_000751"
     CDS             complement(20262..24200)
                     /gene="strH"
                     /locus_tag="VVO77_000751"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEU5692801.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKADVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYDDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKESARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKIISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGG
                     FLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAVTHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQEEDIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKVLPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(24513..25229)
                     /locus_tag="VVO77_000752"
     CDS             complement(24513..25229)
                     /locus_tag="VVO77_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU5692802.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIEFISCDRDH"
     gene            25577..27364
                     /locus_tag="VVO77_000753"
     CDS             25577..27364
                     /locus_tag="VVO77_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEU5692803.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYIAWNLHEPREGEFHFDGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEERGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            27361..27837
                     /locus_tag="VVO77_000754"
     CDS             27361..27837
                     /locus_tag="VVO77_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEU5692804.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            27865..28770
                     /locus_tag="VVO77_000755"
     CDS             27865..28770
                     /locus_tag="VVO77_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU5692805.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            28757..29572
                     /locus_tag="VVO77_000756"
     CDS             28757..29572
                     /locus_tag="VVO77_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU5692806.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            29579..29983
                     /locus_tag="VVO77_000757"
     CDS             29579..29983
                     /locus_tag="VVO77_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU5692807.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            30282..31442
                     /locus_tag="VVO77_000758"
     CDS             30282..31442
                     /locus_tag="VVO77_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEU5692808.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATILVSFARSGNSPESVATVDLAKSLVDELYQVTITCATDGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEY"
     gene            31564..32601
                     /locus_tag="VVO77_000759"
     CDS             31564..32601
                     /locus_tag="VVO77_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEU5692809.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSITPDGVPAKTPEAN
                     RDVVKHIYNGTLLKDIFAEEDEQIQLASGLDHPFALPVGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            32808..33662
                     /locus_tag="VVO77_000760"
     CDS             32808..33662
                     /locus_tag="VVO77_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU5692810.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKEELLTIVQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTRIRLAR"
     gene            33812..34069
                     /locus_tag="VVO77_000761"
     CDS             33812..34069
                     /locus_tag="VVO77_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HEU5692811.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADIVTQLTAVRSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(34237..34365)
                     /locus_tag="VVO77_000762"
     CDS             complement(34237..34365)
                     /locus_tag="VVO77_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004238277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysyl-tRNA synthetase"
                     /protein_id="HEU5692812.1"
                     /translation="MDRTDEVSNHIYGKVKLMWFEEIFEEYKFLHNKTHITKVLMN"
     gene            complement(34399..34491)
                     /locus_tag="VVO77_000763"
                     /pseudo
     CDS             complement(34399..34491)
                     /locus_tag="VVO77_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(34527..34823)
                     /locus_tag="VVO77_000764"
                     /pseudo
     CDS             complement(34527..34823)
                     /locus_tag="VVO77_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            complement(34813..34974)
                     /locus_tag="VVO77_000765"
     CDS             complement(34813..34974)
                     /locus_tag="VVO77_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002875407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HEU5692813.1"
                     /translation="MDKKQAYIVSCHSGLRSYIAEPILKQAGFTVQNLDGAYSLYKMA
                     NPEGVEYGN"
     gene            35044..35808
                     /locus_tag="VVO77_000766"
     CDS             35044..35808
                     /locus_tag="VVO77_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEU5692814.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPCRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            36421..37800
                     /locus_tag="VVO77_000767"
     CDS             36421..37800
                     /locus_tag="VVO77_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEU5692815.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIASRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            37814..38479
                     /locus_tag="VVO77_000768"
     CDS             37814..38479
                     /locus_tag="VVO77_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEU5692816.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            38593..38688
                     /locus_tag="VVO77_000769"
                     /pseudo
     CDS             38593..38688
                     /locus_tag="VVO77_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            38834..39373
                     /locus_tag="VVO77_000770"
     CDS             38834..39373
                     /locus_tag="VVO77_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU5692817.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKCHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDVFVTNFVYEKEGQSRKKSMSYDSVLPVRQIFGWDQVGNFSKGQ
                     YTMMHSLIYRTDLLRASQF"
     gene            39440..39850
                     /locus_tag="VVO77_000771"
     CDS             39440..39850
                     /locus_tag="VVO77_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEU5692818.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLIDQLD
                     LSQVSHPKMREYLLNHIELTTVISSTLLNRSGTAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            39966..>41116
                     /gene="pavB"
                     /locus_tag="VVO77_000772"
     CDS             39966..>41116
                     /gene="pavB"
                     /locus_tag="VVO77_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEU5692819.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADG
                     LNPTPGQVLPEETPGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     SPSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVQKAVADNVKDSIDVPAAYLEKAKGEGPFTAGVN
                     HVIPYELFAGDGMLTRLLLKASDKAPWSDNGDAKNPALSPLGENVKTKG"
BASE COUNT        11368 a         7925 c         9619 g        12204 t
ORIGIN      
        1 actaggattc tagttttgca ggaagtctaa tgtaattttt gcaattcaag acgtttcgat
       61 gactattcaa gatctggatg aaaaatttta aaaaacgatg atatactaaa cttgtcaaag
      121 ttacaacaag acaaaaatta aaaataaaaa agagtatttg tcatggatac aaaaattatg
      181 gaacaatttc atgaaatgga tataactatg ttatctagta ttgaaggagg caagaataat
      241 tggcaaacta atgtcttaga aggtggtggt gctgcttttg gtggctgggg gctagggaca
      301 gctatttgtg ctgcgagtgg tgttggagca ccatttatgg gagcatgtgg atacatagga
      361 gctaaatttg gtgtggatct ttgggcagga gtaacagggg caacgggtgg attttaataa
      421 aaggagactt gtatgaatac ttattgtaat ataaatgaaa caatgctgag tgaggtttat
      481 ggaggtaatt ccggaggagc agctgtagtt gctgctttag gttgtgcagc gggtggagtg
      541 aaatatggga gacttctagg accatggggc gctgcaatag gaggaattgg aggagcagtg
      601 gtttgtggat atttagccta taccgctaca tcataaaaat gaaagctaaa ttttatgaag
      661 gctatattct ttattattct cttcgctttt caaacctatc ttatttatct atccataagt
      721 atctccgata aaaaacaaaa gactattgaa ttaacatcat tgaattgttt tgtcatatta
      781 tttctaatct atgataaatt aatttttctc tttattgcct atgttttttt gataattttt
      841 atattaaact tgttccgtaa ctgaaaagtg atatactata tggatacaaa aatgatgtca
      901 caatttgcag ttatggataa tgaaatgctt gcttgcgttg aaggtggaga tattgattgg
      961 ggaagaaaaa ttagttgtgc agcaggggtt gcatatggcg caattgatgg gtgtgcaaca
     1021 acggtttgac atttctattg ggaccatttg ctataggaat aggtgtaact ggtgctgcgg
     1081 gaggagctat acttggaggt gtggcctatg cagcgacatg ttggtggtaa ttatggattt
     1141 taaaagtttt attattggtt tagtagttgg tatatttggt ccttatatgg atgatttaat
     1201 tagaaaaaaa tttttaaagt cttcggagaa gaaaacagaa aaatctgtta aaaaataatc
     1261 aaaactataa atgatgaatc tgaatcaaaa ttattttgcg catgtaaaga ggagtcttat
     1321 agtaacgagt caaaaaagga gtaactatga atcgtaattt agaacggtgt tatctattct
     1381 gactaggaat agatcatacc agaggtagct tagaaatagc agagacatta gaaattgaag
     1441 taataaatgg gatgtcgtaa gtgttactat caatgattta tttgtttcaa gcttgcctag
     1501 ggtgacagta aaaaatcaat ttcctttcaa tagcatattt ttagtgggca ggactcttgt
     1561 tctgcctatt tttttatcca aaaagtgcag ttgggaggga gataggctca tttgggaagg
     1621 aagtccagtt tttgtttagt gattggggta agatagttgt tatcagatga gtttatactc
     1681 ttcgaaaatc aaattcaaac cacgtcaacg tcgccttgcc gtatatatgt gactgacttc
     1741 gtcagtccta tctacaacct caaaacagtg ttttgagcag cctgcggcta gtttcctagt
     1801 ttgctctttg attttcattg agtattaggg aaaaggagat gaatatgaaa tttgggaaac
     1861 gtcactatcg tccgcaagtg gatcagatgg actgcggtgt agcttcatta gccatggttt
     1921 ttggctacta tggtagttat tattttttgg ctcacttgcg agaattggct aagacgacca
     1981 tggatgggac gacggctttg ggcttggtca aggtggcaga ggagattggt tttgagacgc
     2041 gagccattaa ggcggatatg acgctttttg acttgccgga tttgactttt ccttttgttg
     2101 cccatgtgct taaggaaggg aaattgctcc actactatgt ggtgactggg caggataagg
     2161 atagcattca tattgccgat ccagatcccg gggtgaagtt gactaaactg ccacgtgagc
     2221 gttttgagga agaatggaca ggagtgactc tttttatggc acctagtcca gactataagc
     2281 cttataagga acaaaaaaat ggtctgctct cttttatccc tatattagtg aagcagcgtg
     2341 gcttgattgc caatatcgtt ttggcaacac tcttggtaac cgtgattaac attgtgggtt
     2401 cttattatct gcagtctatc attgatacct atgtgccaga tcagatgcgt tcgacactag
     2461 ggattatttc tattgggcta gtcatcgtct acatcctcca gcaaatcttg tcttacgctc
     2521 aggagtatct cttgcttgtt ttggggcaac gcttgtcgat tgacgtgatt ttgtcctata
     2581 tcaagcatgt ttttcacctc cctatgtcct tctttgcgac acgcaggaca ggggagatcg
     2641 tgtctcgttt tacagatgct aacagtatca tcgatgcgct ggcttcgacc atcctttcga
     2701 ttttcctaga tgtgtcaacg gttgtcatta tttcccttgt tctattttca caaaatacca
     2761 atctcttttt catgacttta ttggcgcttc ctatctacac agtgattatc tttgccttta
     2821 tgaagccgtt tgaaaagatg aatcgggata ccatggaagc caatgcggtt ctgttttctt
     2881 ctatcattga ggacatcaac ggtattgaga ctatcaagtc cttgaccagt gaaagtcagc
     2941 gttaccaaaa aattgacaag gaatttgtgg attatctgaa gaaatccttt acctatagtc
     3001 gagcagagag tcagcaaaag gctctgaaaa aggttgccca tctcttgctt aatgtcggca
     3061 ttctctggat gggggctgtt ctggtcatgg atggcaagat gagtttgggg cagttgatta
     3121 cctataatac cttgctggtt tactttacca attctttgga aaatatcatc aatctgcaaa
     3181 ccaagcttca gacagcgcag gttgccaata accgtctaaa tgaagtgtat ctagtagctt
     3241 ctgagtttga ggagaagaaa acagttgagg atttgagctt gatgaaggga gatatgacct
     3301 tcaagcaggt tcattacaag tatggctatg gtcgagacgt cttgtcggat atcaatttaa
     3361 ccgttcccca agggtctaag gtggcttttg tggggatttc agggtcaggt aagacgactt
     3421 tggccaagat gatggttaat ttttacgacc caagtcaagg ggagattagt ctgggtagtg
     3481 tcaatctcaa tcagattgat aaaaaagccc tgcgccagta catcaactat ctgcctcaac
     3541 agccctatgt ctttaacgga acgattttgg agaatcttct tttgggagcc aaggagggga
     3601 cgacacagga agatatctta cgggcggtcg aattggcaga gattcgagag gatatcgagc
     3661 gcatgccact gaattatcag acagaattga cttcggatgg ggcagggatt tcaggtggtc
     3721 aacgtcagag aatcgctttg gcgcgtgctc tcttgacaga tgcgccggtc ttgattttgg
     3781 atgaggcgac tagcagtttg gatattttga cagagaagcg gattgtcgat aatctcatag
     3841 ctttggacaa gaccttgatt ttcattgctc accgcttgac tattgctgag cggacagaga
     3901 aggtagttgt cttggatcag ggcaagattg tcgaagaagg aaagcatgct gatttgcttg
     3961 cacagggtgg cttttacgcc catttggtca atagctagaa agaggagagg atgaaaccag
     4021 aatttttaga aagtgcggag ttttataatc gtcgttacca taatttttcc agtagtgtga
     4081 ttgtacccat ggcccttctg ctcgtgtttt tacttggctt tgcaactgtt gcagagaagg
     4141 agatgagttt gtccactaga gctactgtcg aacccagtcg tatccttgca aatatccagt
     4201 caactagcaa caatcgtatt cttgtcaatc atttggaaga aaataagctg gttaagaagg
     4261 gggatctttt ggttcaatac caagaagggg cagagggtgt ccaagcggag tcctatgcca
     4321 gtcagttgga catgctaaag gatcaaaaaa agcaattgga gtatctgcaa aagagcctgc
     4381 aagaagggga gaaccacttt ccagaggagg ataagtttgg ctaccaagcc acctttcgcg
     4441 actacatcag tcaagcaggc agtcttaggg ctagtacatc gcaacaaaat gagaccatcg
     4501 cgtcccagaa tgcagcagct agccaaaccc aatccgaaat cggcaacctc atcagtcaaa
     4561 cagaggctaa aattcgcgat taccagacag ctaagtcagc tattgaaaca ggtgcttcct
     4621 tggccggtca gaatctagcc tactctcttt accagtccta caagtctcag ggcgaggaaa
     4681 atccccaaac taaggttcag gcagttgcac aggttgaagc acagatttct cagttagaat
     4741 ctagtcttgc tacttaccgt gtccagtatg caggttcagg tacccagcaa gcctatgcgt
     4801 cagggttaag cagtcaattg gaatccctta aatcccaaca cttggcaaag gttggtcagg
     4861 aattgaccct tctagcccag aaaatcttgg aggcagagtc aggtaagaag gtacagggaa
     4921 atcttttaga caaggggaaa attacggcga gtgaggatgg ggtgcttcat cttaatcctg
     4981 agaccagtga ttctagcatg gttgcagaag gtgccctact agcccaactt tatccatctt
     5041 tggaaagaga agggaaagcc aaactcacag cctatctaag ttcaaaagat gtagcaagaa
     5101 tcaaggtcgg tgattctgtt cgctatacta cgactcatga tgccgggaat caattttttc
     5161 tagattctac tattacaagt attgatgcga cagctactaa gactgagaaa gggaatttct
     5221 ttaaaatcga ggcggagact aatctaactt cggagcaggc tgaaaaactt aggtacgggg
     5281 tggaaggccg tctacagatg attacgggca agaaaagtta tctacgttat tatttggatc
     5341 aatttttgaa caaagagtaa tgttcgtgtt tttagagtta aataattttt aaactgtgag
     5401 aaagattctt cttgcagttt tttctttaca atttttgaaa aacatatgct atttattcgg
     5461 ttaaattctt gtgttttttg gttttttgtg gtaaaatgtg ctcaagtaat acgaaaggcg
     5521 aactttaaaa tgtcaaaaca attgatctat tcgggaaaag ctaaagatat ctatacaact
     5581 gaggatgaaa atcttattat ttcaacttac aaggaccagg cgactgcttt caacggtgtc
     5641 aagaaggagc agattgtagg taagggagtc ttgaataatc agatctcatc ttttattttt
     5701 gagaaattaa atgcggctgg tgtggcgact cactttgtgg agaaactttc agacacggaa
     5761 caactcaata aaaaggttaa gattattcct ttggaagtcg tgctccgcaa ctatactgct
     5821 ggttcctttt caaaacgttt tggtgtggat gagggaatcg ccttggagac tccgattgtc
     5881 gaattttact acaaaaatga tgatttggat gatccattta tcaatgatga gcatgtgaaa
     5941 ttcctacaga ttgcgggtga ccagcagatt gcctacttga aggaagaaac gcgtcgtatc
     6001 aatgaactat tgaaagtctg gtttgctgag attgggctta aattgattga ctttaagcta
     6061 gagttcggtt ttgacaagga tggcaagatt atcttggcag acgaattttc accagataac
     6121 tgccgcttgt gggacgctga tggcaaccac atggataagg atgttttccg tagaggattg
     6181 ggagaactaa ccgacgttta tgagattgtt tgggaaaagt tgcaggaatt gaaataatct
     6241 gtttgcaacg gaaaaccttc gtctctcaac taaaaggact caggctgaaa aggtccccca
     6301 gaccttttca ctctgtagag aactaggtga actaacagat gtttacgaaa ttgtctggga
     6361 aaagttgcag ggtttaaaat aacaacctca aggctgtttg ggaatattgc aagagctgaa
     6421 ataaaggaat aagaattgat ggataaacgt atttttgttg aaaaaaaggc tgattttcag
     6481 gtcaagtcag agagtttggt tagagagctc cagcacaact tgggactgtc aagcttgaaa
     6541 agtattcgta ttgtgcaagt atatgatgta tttgacttgg ctgaggactt gtttgcacct
     6601 gcagagaagc acattttctc tgagcaggga accgaccatg ttttagatga agtatctgtg
     6661 caggcggatc ttgctaacta tgctttcttt gccattgaaa gtctgccagg gcagtttgac
     6721 cagcgtgcag cttcgtcaca ggaagccttg cttttgttgg gaagttcgag tgacgtgaca
     6781 gtcaacacag cccaacttta cttggtgaat aaagatattg atgcgactga gttggaagct
     6841 gtcaaaaact acctgctcaa tccagttgat tctcgtttca aggatatcac gacagggatt
     6901 gccaagcagg agttttcaga gtcagacaag accattccaa aattgacttt ctttgaaagc
     6961 tatacagcag aagactttgc tcgctacaag gccgagcaag ggatggccat ggaagtggat
     7021 gatttgctct ttatccaaga ctactttaag tcaatcgggc gcgtgccaac tgagactgaa
     7081 ctcaaggttt tggacactta ctggtctgac cactgccgtc atacgacttt tgagacagag
     7141 ttgaaacaca tcgacttttc agcttctaaa tttcaaaagc aattgcagtc aacctatgac
     7201 aagtatattg ccatgcgcga ggagttaggt cggtctgaaa aaccacaaac cttgatggat
     7261 atggcgacta ttttcggtcg ttatgagcgt gctaatggac gattggatga tatggaagtc
     7321 tctgacgaaa tcaatgcctg ctcagttgaa attgaagtgg atgttgatgg tgtcaaggaa
     7381 ccttggctcc tcatgtttaa aaatgaaacc cacaaccatc caacagaaat tgagccattt
     7441 ggtggagcgg ctacctgtat cggtggagct attcgtgatc cgttgtcagg ccgttcctat
     7501 gtttaccaag ccatgcgtat ttcaggtgct ggtgatatta cagcaccgat ttcggaaact
     7561 cgtgctggga aattgccaca acaagtcatt tctaaaacag cagctcatgg ttattcttca
     7621 tatggtaacc agattgggct tgccacaacc tacgttcgtg aatacttcca cccaggcttt
     7681 gtagctaaac gtatggaact tggtgccgtt gttggtgcgg ctcccaaggg caatgttgtc
     7741 cgtgaaaaac ctgaagcagg tgatgtgatc atccttctcg gaggcaaaac aggtcgtgat
     7801 ggtgtcggtg gtgcgacggg ctcttctaag gttcaaacag ttgagtctgt agagactgct
     7861 ggtgctgagg ttcaaaaagg aaatgccatc gaagaacgca agattcagcg cctcttccgt
     7921 aatggcaatg tcactcgtct gatcaagaag tccaatgact ttggggcagg cggcgtctgt
     7981 gtggctatcg gtgaattggc agacggtctt gaaatcgacc tcaacaaggt gcctcttaaa
     8041 taccagggct tgaatggtac agaaattgcc atctctgaat cacaagaacg gatggcggtc
     8101 gtggttcgtc ctgaagatgt ggataccttc gttgccgaat gtaacaaaga aaatattgat
     8161 gctgttgtgg tggcgacagt aactgaaaaa ccaaatcttg tcatgcactg gaatggtgag
     8221 acaatcgttg acttggagcg tcgtttcctt gacaccaatg gtgtgcgcgt ggttgtcgat
     8281 gccaaagttg tggacaagga tgtcaaactc ccagaagagc gtcaaacatc tgctgaaaca
     8341 ctggaatcag atacccttac ggttctatct gacctcaacc atgcaagtca aaaaggatta
     8401 cagactatct ttgactgctc tgttggacgc tcaacggtta atcacccact tggtggtcgt
     8461 taccaactca caccaactga ggcatctgtg cagaaattgc cagttcaaca cggtgtgact
     8521 catactgcgt cggtcattgc tcaaggtttc aacccatatg tagctgaatg gtctccatac
     8581 cacggtgctg cttatgcggt tatcgaagca actgctcgtt tggtggctgc tggtgccaac
     8641 tggtccaagg ctcgtttctc ttaccaagag tatttcgagc gtatggataa acaagcagag
     8701 cgtttcggtc agccagtagc tgctcttcta ggttctattg aagcacaaat tcagcttggc
     8761 ttgccatcta tcggtggtaa ggactccatg tctggtacct ttgaagaatt gaccgttccg
     8821 ccaaccttgg ttgcctttgg ggtgacgacg gcagatagcc gtaaggtgct ctctccagaa
     8881 tttaaagctg ttggggaaaa tatctactac atcccaggtc aagccctctc tgcagagatt
     8941 gattttgact tgattaagaa aaattttact cagtttgaag ccatccaagc tgaccataaa
     9001 gtgacatctg catcagctgt caaatacggt ggtgtagttg aaagtttggc tcttgctacc
     9061 tttggaaact atattggtgc agaggtgacc ttgcctgaac ttaaaacagc tttgacagct
     9121 caattaggcg gctttgtctt cacatctcct gaagaaattg ctggagtaga gaaggttgga
     9181 caaacgaaag cagactttac actgactgtc aacggtgtga agctagatgg acacaagctt
     9241 gacagtgcat ttcaagggac attggaagaa gtttacccaa cagaatttac ccaagcgaaa
     9301 gaactagaag aagtaccagc tgtggcatca gatgttgtga ttaaagccaa agaaaaggtt
     9361 gaaaaacctg tggtttacat cccagtcttt ccaggaacca actcagaata tgattcagct
     9421 aaggccttcg aaaaagaagg tgcagaggtc aatttggtgc cattcgtgac cttgaatgaa
     9481 gaagctattg tcaagtcagt tgaaactatg gttgacaata tcgacaagac taatattctc
     9541 ttctttgctg gtggattctc ggctgcggat gaaccagatg gttcagctaa gtttatcgtc
     9601 aatatcctgc ttaatgaaaa agtgtgtgtg gctattgata gctttatcgc ccgtggtggt
     9661 ttgattatcg gtatttgtaa tggattccaa gccttagtca aatcgggtct cctaccctac
     9721 ggaaactttg aagctgctaa cagtactagc ccaaccctct tctacaatga tgccaaccaa
     9781 cacgtggcca agatggtgga aactcgcatt gccaatacca actcaccatg gttggctggt
     9841 gtgcaagtgg gcgatatcca cgctattcct gtttcgcacg gtgaagggaa gtttgtcgtg
     9901 acggctgagg aatttgcaga gctccgtgac aatggacaaa ttttcagcca atacgttgac
     9961 tttaacggta aaccaagtat ggattctaag tacaatccga atggttctgt ccatgccatc
    10021 gaaggaatta ccagcaagaa tggtcaaatc atcggtaaga tgggccactc agaacgttat
    10081 gaggatggtc ttttccaaaa tatcccaggc aataaagacc aacacctgtt cgcatcagcg
    10141 gttaaacatt tcactggaaa ataagactta cagattttct aatagatagt atcagtaatg
    10201 taaaagtcat gtaaatctag ctcttgatga ttacaaatga aaattaggta taaaaaatga
    10261 catacgaagt aaaatctctt aatgaagaat gtggtgtttt cggtatttgg ggacatccag
    10321 atgctgctaa gttgacctat tttggactcc acagtcttca acaccgtggt caggaggggg
    10381 caggaatcct ctccaatgat caaggacaac tgaagcgcca tcgtgacatg gggcttttat
    10441 cagaagtttt cagaaatcca gccaatttgg ataaattgac aggagctggt gcgattgggc
    10501 atgtgcgtta tgcgactgct ggcgaagctt ctgttgataa catccaaccc ttcctcttcc
    10561 gttttcacga tatgcagttt ggtttggctc ataatggaaa tctgaccaat gcagcctctc
    10621 tcaagaaaga actggaacaa agaggagcaa ttttcagcgc gacttcggac tctgaaatct
    10681 tggctcacct cattcgtcgc agtcataatc ctagcctgat gggcaaaatc aaggaagcgc
    10741 tcagccttgt caaaggtggt tttgcctata tcttgctgtt tgaggacaag ttgattgcgg
    10801 ctcttgaccc taatggcttt cgtccgcttt ctatcgggaa aatggccaac ggagcggtgg
    10861 ttgtttcctc tgaaacctgt gcttttgagg tcattggtgc cgagtggatt cgtgatttga
    10921 agccaggtga gattgtgatc attgatgacg agggcattca gtatgacagc tatacagatg
    10981 atacccagtt ggcgatttgt tctatggagt atatctactt tgcccgccct gattctaata
    11041 tccacggtgt caatgtccat acggcacgta agagaatggg agcgcaattg gcgcgagaat
    11101 ttaagcatga ggcagatatt gtagttggtg tgcccaattc ttccctaagc gcggctatgg
    11161 gatttgcgga agaatcaggc ttaccaaatg aaatgggtct gatcaaaaac caatacaccc
    11221 agcgaacttt tatccaaccg actcaagaat tgcgggagca aggagtgcgg atgaaactgt
    11281 ctgctgtttc gggtgttgtc aaaggcaaac gtgtggttat ggtggatgat tccattgtac
    11341 gtggaacaac ctctcgtcgt atcgttcagc tcttgaaaga agcgggtgcg actgaggttc
    11401 acgttgccat tggaagtcct gcactagcgt atccatgttt ctacgggatt gatatccaga
    11461 cccgtcagga gctgattgca gccaatcata cggtcgaaga aactcgccaa atcattggtg
    11521 cggacagtct gacttatctt tcaattgata gcttgattga gtcgattggt atcgaaacag
    11581 atgcgccgaa cggtggtctc tgtgtcgctt actttgacgg tgactaccca acgcctctct
    11641 atgactacga agaagactat cgtagaagtt tggaagaaaa gaccagtttt tacaagtagg
    11701 cgacagattc tccattaaag aaaaggaaaa aacaaatgac aaataaaaat gcatatgccc
    11761 agtcgggtgt ggatgttgaa gcgggttatg aagttgttga acggattaaa aagcacgtgg
    11821 cccgtacgga gcgtgcaggt gtcatgggag ctcttggtgg ctttggtggt atgtttgacc
    11881 tttccaagac tggggttaaa gaacccgtct tgatttcagg gactgacggt gtcggaacca
    11941 agctcatgtt ggctatcaag tacgacaagc acgataccat cgggcaggac tgtgtggcca
    12001 tgtgtgtcaa cgacatcatt gctgcaggtg cggaacccct ctattttctc gactacgtag
    12061 cgacagggaa gaatgaacca gctaagctag aacaagtggt tgctggtgtg gcagaaggtt
    12121 gtgtgcaggc tggtgctgcc ctcatcggtg gggaaacggc tgaaatgccg ggcatgtacg
    12181 gcgaagacga ctatgacttg gctggttttg cggtcggtgt ggctgaaaaa tctcaaatca
    12241 ttgacggttc aaaggtggta gagggagatg ttcttctcgg acttgcttca agtgggattc
    12301 actcaaatgg ttactctttg gttcgtcgtg tctttgcgga ttacacaggt gaggaagtcc
    12361 taccagaatt ggaaggcaag aaacttaagg aagttctact tgagccgact cgtatctatg
    12421 tcaaggctgt cttgccgctc atcaaagaag agttggtcaa cggcattgcc cacatcacag
    12481 gtggtggctt tatcgaaaat gtccctcgta tgtttgcaga tgacctagct gctgaaattg
    12541 atgaaagcaa agttccagtg cttccaattt tcaaagccct tgaaaaatat ggtcagatta
    12601 aacacgaaga aatgtttgaa atcttcaata tgggtgtggg acttatgttg gcggtcagcc
    12661 ctgaaaatgt agagcgtgta aaagaattgt tggatgaagc agtctatgaa attggtcgca
    12721 tcgtcaagaa agaaaacgaa agtgtcatta tcaaatgaaa aaaatagcgg tttttgcctc
    12781 tggtaatggc tcaaattttc aggtgattgc cgaagaattt ccagtggagt ttgtcttttc
    12841 agaccatcgt gatgcctatg tgcttgagcg tgcaaagcag ctcggcgttc tgtcctatgc
    12901 ttttgaactc aaggagtttg agagcaaggc agactacgaa gcagcccttg tcgaactctt
    12961 ggaagaacac cagattgact tggtttgcct agcaggctac atgaaaatcg ttggaccaac
    13021 cttattgtcg gcttatgaag gtcggattgt caacattcat ccagcctact tgccagaatt
    13081 tccaggagct catgggattg aggatgcttg gaatgctggc gtgggtcagt ctggtgtgac
    13141 cattcactgg gtggattcgg gtgtggatac aggccaggtc atcaaacagg ttcgtgtgcc
    13201 acgactagct gatgatacca ttgacagatt tgaagctcgc atccatgaag cagagtacag
    13261 gctgtatccg gaagtagtga aggctctatt tacagattga ctttttgatg attcatatga
    13321 tatctttgat tttaaattgg agtcagtgtt tgttgaagac ggcttcaaac ggaggtattt
    13381 gtaatattag aatctaaaaa aacaactcga tatgtatttt atgtctatct gatgttatta
    13441 acttggggaa tcttatttaa gtttgaaaca aatcctgaat ttatagcatt tttcttagct
    13501 ccaaggtata tcaattggat tccattttca gaaccactaa tagtcgatgg aaaaattgtt
    13561 tttgctgaaa tgttatttaa tctgatttcc tttattccat taggtgtttg tttccctttg
    13621 ataaaaacta atttatctag tttaagaata gtcgggacag gtttcttgat tagtttattg
    13681 tttgagtgct tacagtatat tttagcaata ggtataacag atataacgga tttgacttta
    13741 aatacgctag gtgtctgtgt aggcttactg atttatcaaa tttttataag agtgttcaaa
    13801 tcacagacta gaaaatggat caatatctta ggtatgctta gccttggttt tgcttatctt
    13861 gttttactgt tactgcattt aattggtgtt taactaatga ttaaaaagga gaatataatg
    13921 actaaacgcg tcttaatcag cgtctcagac aaagcgggca ttgttgaatt tgcccaagaa
    13981 ctcaaaaaac ttggttggga gattatctcg acaggtggaa ctaaggttgc ccttgataat
    14041 gctggggtgg ataccattgc tatcgatgat gtgactggtt tcccagaaat gatggacggt
    14101 cgtgtgaaga ccctccaccc aaatatccac ggggggcttc tcgctcgtcg tgacttggat
    14161 agccacttgg aagcggctaa ggacaacaag attgagctca ttgaccttgt ggtggtcaac
    14221 ctttacccat ttaaggaaac tatccttaaa ccagatgcga cttatgctga tgcagttgaa
    14281 aatatcgata ttggtgggcc atctatgctt cgttcagcag cgaaaaatca tgccagtgtt
    14341 acagttgtgg tagatcctgc tgactacgct gtggttttgg acgaattggc agcaaacggc
    14401 gaaacctctt atgaaactcg ccaacgttta gcagccaaag tatttcgtca cacagcggct
    14461 tatgacgcct tgattgcaga atacttcaca gctcaagtgg gtgaaagcaa gcctgaaaaa
    14521 ctcactttga cttatgacct caagcaacca atgcgttacg gtgagaatcc tcaacaagac
    14581 gcggactttt accagaaagc tttgcctaca gactactcca ttgcttcagc caaacagctc
    14641 aacgggaaag aattgtcatt taataatatc cgtgatgcag atgctgctat ccgtatcatc
    14701 cgtgacttca aagatagtcc aaccgttgtg gctctcaaac acatgaatcc atgtggaatt
    14761 ggtcaagctg atgacatcga gactgcttgg gactacgctt atgagtctga cccagtgtct
    14821 atctttggtg ggattgtcgt cctcaaccgt gaggtggatg ctgcgacagc tgagaagatg
    14881 cacggcgttt tcctcgaaat catcattgca ccaagctata cggatgaagc gctagccatt
    14941 ttgatcaata aaaagaaaaa cttgcgtatc cttgccttgc catttaatgc tcaagaggct
    15001 agcgaagtgg aagcagaata cacaggtgta gtcggtggac ttctcgtgca aaatcaagac
    15061 gtggtcaagg aaagcccagc tgactggcaa gtggtgacca aacgtcagcc aaccgagaca
    15121 gaagcgactg ctcttgagtt cgcttggaag gctatcaagt acgtcaaatc aaatggtatt
    15181 atcgtgacca acgaccacat gacacttggt gttggtccag gtcaaaccaa ccgtgtggct
    15241 tctgttcgcc ttgccattga ccaagccaaa gatcgtctgg acggggcggt ccttgcttca
    15301 gatgccttct tcccatttgc ggataacgtg gaagaaatcg ctaaagcagg aattaaggcc
    15361 atcatccagc ccggtggctc tgtccgtgac caagaatcca tcgaagcagc ggataaatac
    15421 ggcttgacta tggtctttac aggtgtgaga cattttagac attaagaaga taaaagggaa
    15481 gaaaacagtt tctttccttt tttggcttaa aatgctaact gaaacaagat taaaacgaac
    15541 ttttttgata taatattggt aaataattcg caaaagaggt tgaggaatga aactgcttgt
    15601 tgtcggttcg ggtggtcgtg agcatgcgat tgctaaaaag ttacttgaat caaaagatgt
    15661 ggaaaaagtc tttgtagctc ctgggaatga tgggatgact ctggatggtt tggaattggt
    15721 aaatatctct atttccgaac attctaaatt gattgacttc gcaaagacca atgatgttgc
    15781 ttggaccttt atcggtccag atgatgccct tgctgctggt atcgtggatg attttaacca
    15841 agctgggctt aagacctttg gtccgactag ggctgcagcg gagctggagt ggtccaagga
    15901 ttttgccaag gaaatcatgg tcaaatatgg tgtttcgaca gcagcctatg gcacattttc
    15961 agatttcgag gaagcaaagg cttatatcga aaagcatggt gcgcctatcg tagtcaaggc
    16021 ggatggcttg gcgcttggga agggtgtcgt cgttgctgag acggttgagc aagcggtcga
    16081 agccgctcat gagatgcttt tggacaataa atttggtgac tcaggtgcgc gcgtggttat
    16141 tgaggaattc cttgaaggag aggaattttc actctttgcc tttgtcaatg gtgataagtt
    16201 ctacatcatg ccaacggctc aggaccacaa acgtgcctac gatggcgaca aagggcctaa
    16261 cacgggtggt atgggtgcct atgcgccagt tccacactta ccacagagtg tagttgatac
    16321 agcggttgac accattgtca agccagttct agaagggatg attaaagaag gtcgccctta
    16381 tctgggagtt ctttacgcag ggcttatcct gacagctgat ggaccgaaag tcatcgagtt
    16441 caacgctcgg ttcggagatc cagaaactca gattatcttg cctcgcttaa cctctgactt
    16501 tgctcaaaat atcacagata tcctggatag caaggagcca aatatcatgt ggacggacaa
    16561 gggtgtgact ctgggtgtgg ttgtcgcatc caagggctac ccgctagact atgaaagggg
    16621 cgttgagttg ccagccaaga cagaaggcga tgtcatcacc tactatgcag gggctaagtt
    16681 tgcggaaaat agcagagcac tgctctcaaa cggcggacga gtttatatgc tcgttaccac
    16741 agcagatacc gtcaaagaag cccaagccag catctaccaa gaactatccc aacaaaaaat
    16801 agaaggactc ttctaccgaa cagatatcgg aagcaaggca attaagtaaa gatataagaa
    16861 taacgcgccg tagtcgccaa acacgataat ggtcgtcgtg gtgaaaagac cagaacagtg
    16921 aatgttctgg tcagggggaa atttggagac cgtaggctca aagtttagga atgaaaccga
    16981 aggtttgctt ccgcctccat cacctaagat cattattaaa aaagaagaaa aggaaaatta
    17041 tgaccaaacc aattatttcc atcatcatgg gctcaaaatc cgattgggca accatgcaaa
    17101 aaacagcaga agtcttagac cgcttcggtg tagcctacga aaagaaagtt gtttctgccc
    17161 accgtacacc tgatctcatg ttcaaacatg cagaagaagc atatagccgt ggtattaagg
    17221 tcatcatcgc aggtgctgga ggcgcagccc acttgccagg aatggtagct gccaaaacaa
    17281 cccttcctgt cataggggta cctgtcaagt ctcgtgctct tagtggagtg gattcactct
    17341 attctatcgt tcagatgccg ggtggggtgc ctgttgcgac catggctatc ggtgaagctg
    17401 gagcgactaa cgcagctctc tttgccctcc gtctcctctc tgtagaagat aagtccattg
    17461 cggatgcact tgccaacttt gctgaagaac aaggaaaaat cgcagaggag tcgtcaaatg
    17521 agctcatcta aaacaatcgg aattatcggt ggcggtcaac tgggtcagat gatggccatt
    17581 tctgctatct acatgggcca caaggttatc gcgctggatc ctgcggcgga ttgcccggtc
    17641 tctcgtgtgg cggaaatcat tgtggcacct tataacgatg tagacgccct ccgtcagttg
    17701 gcagaccgtt gcgatgtcct cacttacgag tttgaaaatg tcgacgctga cggtttggat
    17761 gccgttatca aggatggaca actccctcaa gggacagacc tgctccgcat ttcgcaaaat
    17821 cgtatttttg aaaaggactt tttgtcaaac aaggctcaag tcactgtggc accctacaag
    17881 gtcgtgactt ctagcctaga cttggcagat atcgacttgt cgaaaaacta tgtcctcaag
    17941 actgcgactg gtggctacga tggtcatgga caaaaggtta ttcgttcaga agtagacttg
    18001 gaagcagcct atgcgctagc agaatcagca gactgcgtct tggaagaatt tgtcaacttt
    18061 gcccttgaga tttctgtcat cgtgtcagga aatggcaagg aggtgacgtt tttcccagtt
    18121 caggaaaata tccaccgcaa caatatcctg tctaagacca tcgtaccagc ccgcatttct
    18181 gaaagtctag tagacaaggc taaagctatg gcagtgcgaa tcgcagaaca actcaacttg
    18241 tctggaactc tctgtgtgga aatgtttgcg actgatgatg acgttattgt caatgaaatc
    18301 gccccacgac cacataactc tgggcactat tctattgaag cctgtgattt ctctcagttt
    18361 gacacccata ttctcggtgt tctcggagca ccattaccag tcatcaaact ccatgcgcca
    18421 gccgttatgc tcaatgtcct aggtcaacac gtcgaggctg ctgaaaagta tgtcgcagaa
    18481 aatccaagcg cccacctcca catgtatggt aaaatagaag caaagcataa tcgtaagatg
    18541 ggacatgtga ccttgtttag tgatgtaccg gatagtgtgg atgagcttgg ggaagggatt
    18601 gatttttagg acaagtctat gatacaaatt atcgttaata catttattga aaaggataag
    18661 actggagcag ttgttgaagt gttgtatgcc agtgctgacc aagataaggt acaagctaaa
    18721 tatgaagaac tagctgcaca ataccccgaa aattatttag ctatctatga tgtaccgctg
    18781 gatacggatt tgaatacact agatcattac ccgtctgtgt ttattggaaa agaggagttt
    18841 gagtagaaat cttggtttac ctagatagct tattcccaac agcttaagaa gaaaggaaaa
    18901 attaacacat gatcaaccgt tactctcgcc ctgagatggc gaatatttgg agtgaagaaa
    18961 ataaataccg tgcttggctt gaggtggaaa tcctctctga cgaggcatgg gctgagttgg
    19021 gggaaatccc taaggaagat gtggctttga ttcgcaagaa ggcggacttt gacatcgacc
    19081 gtattttgga aattgagcag gagacgcgcc acgatgtggt ggctttcacg cgtgcggttt
    19141 ctgagactct tggtgaagag cgcaagtggg ttcactatgg gttaacttct accgacgtgg
    19201 tggatactgc ttatggttac ctctacaagc aggccaacga catcatccgt cgtgaccttg
    19261 aaaacttcac taatatcatc gctgacaagg ccaaggagca caagttcacc atcatgatgg
    19321 ggcgtactca tggtgtgcac gctgagccga caacctttgg tcttaaattg gcaacttggt
    19381 acagcgaaat gaaacgcaat atcgagcgct tcgagcatgc ggctgctggt gtagaagctg
    19441 gtaagatttc tggtgcggtt gggaactttg ccaatatccc accatttgta gaggagtatg
    19501 tctgcgataa acttggcatc cgtgcccaag aaatctctac acaagtcctt cctcgtgacc
    19561 ttcacgctga gtactttgcg gttcttgcca gcattgcgac ttcaatcgaa cgtatggcga
    19621 ctgagattcg tggtctacaa aaatctgagc aacgcgaagt agaagagttc tttgctaaag
    19681 ggcaaaaagg gtcttcagca atgcctcaca aacgcaaccc aatcggttct gaaaatatga
    19741 ctggtctggc gcgtgtcatt cgtggtcaca tgattacggc ttatgaaaac gtcgctctct
    19801 ggcacgaacg cgatatttct cactcatcag ctgagcgtat catcacacca gatacgacca
    19861 ttttgattga ctacatgctc aaccgttttg gaaatatcgt caagaacttg acagtcttcc
    19921 cagaaaatat gatccgaaac atgaactcga cttttggtct tatctttagc caacgggcta
    19981 tgttgacatt gattgaaaaa ggcatgaccc gtgagcaagc ctatgacttg gtgcaaccaa
    20041 aaacagccta ctcttgggac aaccaagtag actttaaacc acttcttgag gcagattcag
    20101 aagtaacatc acgtctcaca caagaagaaa tcgatgaaat cttcaaccca gtttattaca
    20161 ccaaacgagt ggatgatatc tttgaacgtc ttggactagg tgattaatta aaaaataaac
    20221 agcgagcttc aatctcgctg tttatttttt atcgaaaaga cttagtcttc ttttctttta
    20281 gtgagtccat aggctgctag tgtggacatg agtcctgcga ctactagtcc tgcagaatcg
    20341 tgagttcctg tttcaggaag ttttttctct gttaccacag gagctggatc ttgaggaaga
    20401 actttgcttt cctcagcagg agcagttgat ggagctggtt ggcttgggat ttctagtttt
    20461 ggtttttctt cagcaatagc ggcttgtccg ttttcatcgc ctacatgtgt taccatagtt
    20521 ccgacttcga ctatttgagt aacggcttcc tgtgctacga cactatttac aagtgttttc
    20581 acttccttac catcggcaga agtgctcaca gagtagaagt tgctacgatg tccattgacg
    20641 cccttagtaa tgacttgtgt ttttcctttg agtaagagtg gattttcacg agtcactgtg
    20701 gtaaatggaa tgtcttcttc ttggatatcc agtctaggtt ttacctcagt agttggtgca
    20761 agaccacttt catcaccctt gtgagttaca ggagcgccaa cttcaaccac ttggtttata
    20821 acttctttgg ttacctggct atcaaggact gtttctgttg tttttccatt ttcagtgagt
    20881 acagagatgt aatgagttcg ttcacctttg actcctgctg tgataatatt ttcctgaccg
    20941 gctgggaggt taggattttc tttcttgata acttcaaatg gaatttcttc agttcttgtg
    21001 atgagttctg gtctggtttc aacattggca gccacttcat tttcatctag gcttcctgaa
    21061 tgagttacag ctggtttgag gccttgaaga gcggctttta ggttggctac aagtgtgtca
    21121 agctcagctt gtttattacg gttgaggttg taatttagag ctgttttagc tgcgtcaagg
    21181 gcctcaagac tttctttact atatccttct aagtttgtag gaattttagc taattcttcg
    21241 cggagagcat tataattagc acggaagtag tctttgttgt ggtctgcaaa ggcagtcatg
    21301 agttcaaaga tttcctcttc cttgtattca gcgcttggtc tatctgccca gattgaaagc
    21361 atacttccga ctgttggaag atctacttca ggatatttgg tagaagctag ttgattgaat
    21421 ggtgtttttc cagtattctc aatagctttc ttgaggaaac caccaccatc ttctggtttt
    21481 tgaccaagaa tgtagtacca gtcaccgttg gtattcaaga atttatagcc tttgcttgct
    21541 aggtattgag gtgatgcgag gttatatccc caccagcctt tagaccagta agaaatcaag
    21601 acatctttgt caaactgaac atcgtccttg tcttcatagt agaagccatc gttgaaggcc
    21661 attggttgaa gccctctttc tttggccata gctgcgaggg tgttggcata ttcggcaaat
    21721 ttgccataga gttgatacca cttgaggtag taccagcctt gggcactagt cgcatcgttg
    21781 gcgtattcgt cagtaccaaa gttgaaaatc tttgttttac ctgcaaagaa gtccatgtat
    21841 ttaccgatga gggcttttac aaagttcatc gcttcttcgt ttttcaagtc catagttgtt
    21901 tttgaaactt tatcaaagtg ggcttgagga tttttaatac ctaatttttc catggcaacc
    21961 agcatagcat ccatgtgacc tggactgtta atagctggga tgagaccgat gtccttagat
    22021 ttagcgtatt caattagctc tgtcacttct gcctgtgtta gtgcagtacc gtttggatcg
    22081 tcgtagtaag ctttagttcc ttcgataata gcttttttaa cgtcatcact agcataggtt
    22141 tttccgttgg cagtaatggt catatcatcg agtagaaagc gaagtccgtc atttcctaga
    22201 aggagatgga catcagaata tccgagctca ctggccttgt ctacgatgcg tttgagctgg
    22261 ttcagagtaa agtatttgcg tccagcatcg attgagatta tcttgttttt ggcaagtttt
    22321 tcaacctcac gtttagcttc ttcttctttt tgagcttcag gcgtgagggt caagttgttg
    22381 acagtttctt gaagtttagc aatggcttga tcaatcgtat cttgttgggc acggctaagg
    22441 ttgctatcga gagagcgaat agctttttca gcttctttta cggccgtgac gctttctgca
    22501 gtataacggt tcaggtcttt tggtacctcg ttaagtgctt gctctgcaga ttcataatca
    22561 gctgcgaagt attcagcgtt ggcatttgca aaatgacgca tgagtttgaa gaggcgtgat
    22621 ggtgaataac gtgcagatgg agtgtcagcc caagcagcta ccataccacc gatgattggg
    22681 atatcagctc cttctgtttt tggtacagaa gtgattggtg tgtttttaat accattgagc
    22741 ccctgatcga gattgtacca gccttggcca tcagcgtttc gtccaagaac gtagtaccaa
    22801 gcatcattgg tattaaggat ttggtgacct ttttcagcta gtagtttaga agaagcgaca
    22861 tcgtagcctc cccaaccacc agtccacata gaaacgatga tgtctttgtc aaaactacca
    22921 aagcttgtgt cgctattgta gtagataccg tcgttaaagg ccattggttt gagaccgtgc
    22981 gattttacaa tacgagcgag gtcattggcg taggcaataa atttttcata gccttttaca
    23041 gggtagcctt cgtttggata gtatttatca gcttgaagca cactccaacc tttagcatct
    23101 gtcgcatcat tggcatattc atcaagtccg atgttgaaga tttcagtctt tttcgcgaaa
    23161 taagcagcat acttgtcgat aagggctttt gtaaaagcga cagcttgttc gttgtcaaga
    23221 tcgacagtac gggctgattc cttcccaaaa tagctaaagt tagggttttg gattcccaat
    23281 tctttcatgg cattgagaat cgcatccatg tgcccaggac tatttactgt cggaatgaga
    23341 ccgatacctt tatctttggc atagttaatc agatctgtca tttgactttc tgttaagtga
    23401 ttgccgtttg gatcgtcgta ataatcattt gtaccttttt caatggcgcg tttgacatcg
    23461 tcactggcat aggtcttgcc gttagctgtg atgctcatat cgtccaacat gaaacggagt
    23521 ccatcatttc cgactaatag gtgtaaatca gtgtagccat aatgtttcgc tttatcgatg
    23581 atttccttga gctgttctgg tgagaaatat ttacgtccag catcaataga aacaattttc
    23641 tttttcgcta gtttttcatt tacagttgca gcacgttcct ttcctgcctc tgtttccggt
    23701 ttgtcagcct ctgctttcgc ttcatctttt ttagctggtt tatccttgtc agtcttgtct
    23761 gtatttgact ctttagaatc aacctctttc gcttcttcct ttttagggct agcttcttct
    23821 gcctttttat tagcagtttc tttttcagca gaagttggag ttaccacgtc tgctttatca
    23881 ctaggagttg aactaacttc ctcttgtggt ttttcttctg tttttggaag actagctacc
    23941 ttatcagtag ctggagtttc tgtttctaca gtttttggag cttctggttg aagctctgct
    24001 ttaggtgttt cctcagtccg attttcggat gattgagggg aatcagaaac cgtatggatg
    24061 gtcggttggt tttctgtagt agtaggagta actccatcgg ctgcaacagt ctgtgcttgg
    24121 aaggcaaatc caattagaac agaagctgct cctacagcgt atttacgaat agaaaaacgc
    24181 tgttgttttt catgtttcat tgcaaaacct cctgattgca ttgttatatt gatagcgatt
    24241 atataaatca acgcctttat tttatttctt atattaacga gagtcaagag gagatgacaa
    24301 aaaactataa taagtataaa aaaatataaa atttaaactt aagatttcag attggtcgaa
    24361 aatacatata tatatctagt ataatttttg gttctatttc tataaaatat tccacaaatt
    24421 atagaatctt ccaaaaatag gtaagcgcta cctttttggt gtggtataat aagcatagaa
    24481 aaagcccgag cgattaggct caggctttct tcttagtgat cacggtcaca tgagatgaat
    24541 tcaatcttgt agtaatcaga tcgtttgtaa gtttcactgt attctaaaac ttggccagtt
    24601 gattcgagtt tggtgatttt agtttgtagg acagtaggga attgttcatc gactccgagg
    24661 actgaagccg catgttctgg agttggaaag actatttcgt tgatttcttc aaagtgttca
    24721 tcattcatgt gaatgtggta gtctaacttg aaacgattat agatagaact atagtattca
    24781 aggtttggat aatttgcgtt gatatattgt tctgggatgt aggatgtatg gtagatataa
    24841 acgacaccgt ttgattcgcg gatacgttca atcttgtagt agaattgatc gccgcgtaga
    24901 cccaattttt ccaagtaaac aagcttgttt ccgcgttcaa ttgaaagaac agttacctta
    24961 tcatctttag cattgaagag ttcaatatct gaaaactcta caagcttgtg tttgcgtgca
    25021 cgtgaaacga aggttccttt tccttgttgg cggacaatat agccatcttt ggcaaggtcg
    25081 tttaaggcgc gaacaactgt gatagagctg acatcgtaca ttgaaatgag ttctgcttca
    25141 gtgtaaaatt tatctccact gctaaactgc ccagagatga ttttattttt taattcgtct
    25201 tttatgtatt gatatttggg aattgccata tttttacctc tattttcctt ctccatagaa
    25261 aattttacca taaaagcgaa aaaaatagta gtcttttgaa taaaaaatta gaataatagt
    25321 ttgaaaaatt aagcgatata gggattgctc atattttatc aatgtattct atacaaaatt
    25381 attttaggtc ctatattccg aatttaaaga gcgtttgaaa tgggtctaaa aatgtttgaa
    25441 actaattgaa tgtgtgtata atagtaaaaa tgcagtaaat atcccgacaa tttctattga
    25501 caattcaaac agattggttt ataattaata taacaacaaa tgaaagcgca aactttcgcg
    25561 gtcggaaggt agttttatga cacgatttga gatacgagat gatttctatc tcgatggaaa
    25621 atcatttaag attttatctg gtgccattca ttattttagg gttcctccag aggattggta
    25681 tcattcgctc tataacttga aggctcttgg ttttaatacg gtagagactt atattgcttg
    25741 gaatttacac gagcctcgtg aaggtgagtt tcattttgac ggtgatctgg atttagagaa
    25801 atttctccaa atagcgcagg atttgggtct ctacgcaatt gtgcgtccgt ctccatttat
    25861 ctgtgcggaa tgggaattcg gtggcttacc agcttggctc ttgaccaaga acatgcgaat
    25921 tcgctcatcc gacccagcat atatcgaggc agttggtcgc tactatgatc agttattgcc
    25981 aagactggtg cctcgtttgt tggacaatgg tggcaatatt ctcatgatgc aggttgaaaa
    26041 tgagtatggt tcttacggag aagataaggc ttacctgaga gcgattcgac agctaatgga
    26101 agagcgtggc gtaacctgtc ctctctttac atcagatggt ccatggcgag ctactctgaa
    26161 agctggaacc ttaattgaag aggacctctt tgtaacagga aactttggtt ctaaggcacc
    26221 ttacaacttt tcgcagatgc aggaattctt tgatgaacat ggtaagaaat ggccactcat
    26281 gtgtatggag ttctgggatg gttggtttaa tcgctggaaa gaaccgatta tcacacggga
    26341 tcctaaggaa ttggcagatg cagttcgaga ggttttggaa caaggctcta tcaatcttta
    26401 catgttccac ggtggtacaa actttggttt catgaatggt tgctcggctc gaggaacttt
    26461 ggacctgcca caagttacgt cttatgatta cgatgccctt ctggatgaag aaggaaatcc
    26521 aactgctaaa tatcttgcag tcaagaagat gatggcaaca catttttcag agtatccgca
    26581 gttggaacca ctctacaaag agagtatgga gttggatgct attccactag ttgaaaaagt
    26641 ttctttgttt gaaaccttag atagcttgtc aagtcctgta gaaagtctct atcctcaaaa
    26701 gatggaggag ctgggacaaa gttatggcta cctactttat cgaacagaaa caaactggga
    26761 tgcagaagaa gaaagacttc gtatcattga tggtcgagat agggcccagc tgtatgtcga
    26821 tggtcagtgg gttaaaactc aatatcagac agagattggg gaagatattt tttatcaagg
    26881 taaaaagaaa gggctatcta ggttagatat cttgatagaa aatatggggc gtgtcaacta
    26941 tgggcataag ttcttagcgg atacgcaacg taagggaatt cggacagggg tctgtaagga
    27001 tctgcatttc ttactaaact ggaaacacta tccacttcca ctagacaatc ctgagaaaat
    27061 tgatttttca aaaggatgga ctcaaggaca accagccttt tacgcttatg actttacagt
    27121 cgaagagcca aaagatactt acctagactt gtctgagttt ggtaagggag ttgcctttgt
    27181 caatgggcag aatctaggac gtttttggaa cgttggccca actctctcac tttatatccc
    27241 tcatagctat ctcaaggaag gtgccaaccg catcattatc tttgaaacag aaggtcaata
    27301 taaagaagag attcatttaa ctcgtaaacc tacactaaaa catataaagg gggaaaactt
    27361 atgacaattg taggatgccg tattgatgga cgtttgatcc acggacaagt agccaatctt
    27421 tgggctggaa aactaaatgt ttcacgcatt atggttgtag acgacgaagt tgtcaacaac
    27481 gatattgaaa agagtggttt gaaacttgcg acaccaccag gtgtgaaatt gagtattttg
    27541 ccagttgaga aagctgcagc caatattctt gctggtaaat acgatagcca acgtctcttt
    27601 atcgtggctc gtaaaccaga ccgcttcctt ggcttggtag aagcaggtgt accacttgaa
    27661 acccttaatg ttgggaatat gtctcaaaca ccagaaactc gttctattac acgttctatc
    27721 aacgtagtag acaaggatgt ggaagacttc cacaaactgg cagaaaaagg tgttaaactt
    27781 actgctcaga tggttccaaa tgatccaatt tcagactttt tgagcttatt aaaataggaa
    27841 aaaaattttt aggaggtcat tgttatgata caatggtggc aaattttact tctcactttg
    27901 tactcagctt atcaaatctg tgatgagttg acgatcgttt catctgcagg ttcccctgta
    27961 tttgctggtt tcattactgg tttaatcatg ggagatgtga ctactggttt acttatcggt
    28021 ggtaacttgc aactgttcgt tcttggggtt ggtaccttcg gtggtgcttc tcgtatcgac
    28081 gcaacttctg gtgcggttct tgcgacagcc ttctctgttt cacaaggaat tgatgcaccg
    28141 cttgccatta ctacaatcgc tgtaccagta gcagctctct tgacttactt cgacgttctt
    28201 ggtcgtatga ctactacctt cttcgctcac cgtgtggatg ctgcaatcga acgctttgac
    28261 tataaaggta ttgaacgcaa ctacttgctt ggtgcgattc cgtgggctct atctcgtgcc
    28321 cttccagtct tctttgccct tgcttttggt ggtgcctttg tacaatcagt agtagacttc
    28381 gttgaagcct acaaatgggt tgcagatggc ttgacacttg caggacgtat gcttccaggt
    28441 cttggatttg caatcttgct tcgttacctt ccagttaaac gtaaccttca ctaccttgct
    28501 atgggatttg gtttgacagc tatgttgact gttctttact catatgtaac aggtcttggt
    28561 ggcgctgttg ctggtatcgt aggtactctt cctgctgaag ttgctgaaaa aattggtttc
    28621 gtgaacaact tcaaaggttt gtctatgatt ggtatttcta tcgtaggtat tttccttgca
    28681 gtgcttcact tcaaaaatag ccaaaaagta gctgtagcag caccttctac accatcagaa
    28741 agtggggaaa tcgaagatga cgaattctaa ttacaaactt acaaaagaag attttaatca
    28801 aatcaacaaa cgtagcttgt ttactttcca attaggttgg aactacgaac gtatgcaagc
    28861 ttctggttac ctttacatga tcttgcctca gttgcgtaaa atgtatggtg atggaactcc
    28921 tgaattgaaa gaaatgatga aagttcatac tcaattcttc aatacttcac cattcttcca
    28981 taccattatc gctggttttg accttgccat ggaagaaaaa gatggtgtag gttcaaaaga
    29041 cgctgttaac ggtatcaaga caggtttgat gggaccattc gctcctcttg gggatacaat
    29101 ctttggttca cttgtacctg ctatcatggg gtcagtcgca gcaactatgg ctatcgctgg
    29161 ccaaccttgg gggatcttcc tttggattgc agttgcagta gcgtatgaca tcttccgttg
    29221 gaaacagttg gaatttgctt acaaagaagg ggttaacctt atcaacaaca tgcaaagtac
    29281 cttgacagct ttgattgacg ctgcatctgt acttggtgtc ttcatgatgg gtgctcttgt
    29341 agcaacagtg attaactttg aaatttctta caagttgcca atcggtgaaa agatgattga
    29401 tttccaagac atcttgaacc aaatcttccc acgtttgctt ccagcaatct ttactgcctt
    29461 tatcttctgg ttgcttggta agaaaggtat gaactctact aaagctatcg gtattattat
    29521 cgtacttgct ttggctcttt ctgcccttgg tcactttgca cttggaatgt aattccttat
    29581 gactaaatca ttaattttgg tgagccatgg tcgcttctgt gaggagctta gaggtagcac
    29641 agaaatgatt atgggcccac aagacaacat ttacacagta gctcttcttc cagaagatgg
    29701 cccagaagaa tttactgcta aatttgaagc tgttattgaa ggattggatg atttcctagt
    29761 ttttgcggat cttctcggtg ggacaccttg taatgtggtg agtcgcttga tcatggaagg
    29821 tcgtgatatt gacctttacg cagggatgaa tcttccaatg gtgattgaat ttatcaatgc
    29881 gagccttaca ggcgcagatg cggactacaa gagccgtgct gcagaaagca ttgtgaaagt
    29941 taatgacctg ttagcgggct tcgatgatga cgaagatgaa taatactctt cgaaaatctc
    30001 ttcaaactac gtcaacgtcg ccttaccgta ggtatatgtt actgacttcg tcagtcttat
    30061 ccggcaacct caaaacggtg ttttgagctg acttcgtcag tcttatccgg caacctcaaa
    30121 gcagtgcttt gagcagcctg cggctagttt cctacagatt ttagttggaa ctcgattcaa
    30181 ttcatgtgac aacgtgaaaa tcgttagagc attttatata gaatatacat gggaatggag
    30241 cttactccca ttcctatatt taatagaaaa agaggaactc aatgctacat tatacaaaag
    30301 aagacttgct cgaattgggt gcagaaatca ctacgcgtga aatctaccaa cagcctgatg
    30361 tatggagaga agcttttgaa ttttatcaag caaaacgtga agaaattgca gccttcctac
    30421 aagaaatcgc tgataaacat gactatatta aggttatctt gacaggtgct gggacttctg
    30481 cttatgtggg agacaccttg ctaccttact ttaaggaagt ctatgacgaa cgcaaatgga
    30541 atttcaatgc tattgcgaca acagatatcg ttgccaatcc agcaacctat ttgaaaaaag
    30601 atgtggcaac tatccttgtg tcttttgctc gtagtgggaa ctcgcctgaa agtgtggcga
    30661 ctgttgattt ggccaaatcc ttggtggatg agctttatca agtgacgatt acttgtgcaa
    30721 cagatggtaa attggctctt caagctcacg gtgatgaccg taatctcttg ctcttgcaac
    30781 cagctgtctc taatgatgct ggatttgcca tgacttctag ctttacgtct atgatgttga
    30841 cagctctctt ggtctttgat cctacagaat ttgctgttaa gtctgaacgt tttgaagttg
    30901 tatctagtct tgcccgtaaa gttttagaca aggcagaaga tgtcaaagag ctcgttgatt
    30961 tagactttaa ccgtgtcatc tatctaggcg ctggtccttt ctttggactt gctcatgaag
    31021 ctcagctcaa gattttggaa ttaactgctg gtcaagttgc gaccatgtat gaaagcccag
    31081 ttggcttccg tcacggtcca aaatctctta tcaacgacaa tacagttgtt ttggtctttg
    31141 gtacaacgac agactacact cgtaagtacg acttggactt ggttcgtgaa gttgctggtg
    31201 accagattgc tcgtcgtgtt gtgcttttga gtgatcaagc ttttggtctt gaaaatgtca
    31261 aagaagtggc ccttggttgt ggcggtgtct tgaatgatat ttaccgtgtc ttcccttaca
    31321 tcgtttatgc ccaactcttt gccctattga cttcactcaa ggtagaaaat aaaccagata
    31381 caccgtctcc tacaggtaca gtaaaccgtg tagtacaagg tgtcataatt cacgaatatt
    31441 aaaagtaaga cagtgtttat gaattcttga caagaggatt tgtaaattat cagataaacc
    31501 atagattgtc agtacgcttt ctatggtttg tttgcttgag agaaatagta aaaggagaac
    31561 agaatgaaag catacacaga gcgtgtattt ggaaatgttg agggcgagga tgtcttggcc
    31621 tatcgatttg agacagacgg tggctaccaa cttgaggtta tgacttatgg cgcgaccatc
    31681 ttgcgctatg tcgcacctga caaggctgga aattttgcca atgttatctt gggatttgat
    31741 gactttgata gttatgtagg caatagtccc aagcatggag caagtgtagg tcctgtagcg
    31801 ggtcgtattg caggtgcgac ctttgagctc aatggtaaga cctatgacct tgaggttaat
    31861 aatgctagca actgtaatca cagtggttca actggttggg attccagctt gtttgaagtt
    31921 gaagaagtaa gcgatcatgg cttgactctc tacacagaac gtacagatgg gacaggaggg
    31981 ttccctggaa atctcaagat ttggatcagt tatcacttgg aagaaactgg tgcctatgaa
    32041 attagctaca aggtaacgac cgatcaggat acgctggtca atccaaccaa ccacagctat
    32101 ttcaacttgt ctggtgattt cacgcagacg attgaccgtc atgtcttcca actaaacaca
    32161 gagggcattt actcaatcac tcctgacggt gttcctgcca aaactccaga agccaaccgt
    32221 gatgtggtca aacacatcta caatggtacc ttgttgaagg atatctttgc agaagaagat
    32281 gagcaaatcc agctggcatc aggtttggat cacccatttg cccttcctgt aggccatgac
    32341 aatgctggat tcctttatga ccaaaattca ggtcgcttcc tgcttttcaa gacagaagct
    32401 ccttgctttg tggtctacac agcaaacttt gtggatgaaa gtgtcatcat aggaggtcag
    32461 ccaatgctac agcacaatgg gattgctctt gaagcgcaag ctttaccaga tgccattcac
    32521 agtgacctta aaggccaagt cattcttaaa gctggtcaaa ccttcaccag taagacacgt
    32581 tatgaacttg ttgtgaaata aaaaagctgg tcaaaaagtc tttaaaatta aaataacgca
    32641 tattgtcagg tgatgaaaag tttgatacta tgcgttttat tatgaaatga tttactttat
    32701 cttatcctga aatggtgtta tttttgagtt atctggcttg actttcttga tggaaattat
    32761 ataatagttg taataacaat aattacaacg agaaaagagg accatttatg acctatgaat
    32821 acaagagtca catttatttg gcagagacag ttttaaatgt aaaggatttg gccagtcaaa
    32881 cagcctttta tcagcaagtt attggtttag aaatcttatc tcaaactgag acagagtcca
    32941 ttctaggcct tggtggaaaa gtcttggtac agctgattca agcacaagag agcggagaag
    33001 tgagggaaca ttatggtctt taccatttgg ccattctctt gcccacacgc aaggctttgg
    33061 ctgatgtctt gaaacacctg acagatttac agattcctct tgtcggcggt gcagaccatg
    33121 gttacagtga agctatttac ttggaagatt tggagggaaa tggcattgaa ctctatcgag
    33181 ataagccagt ttccacatgg gatattcgag aagatggacg cattatcgga gtgacggagg
    33241 ctcttgcggc gcaggacatt tatgagttgg gggaaagagt agagcccttt atcctggcag
    33301 aaggtacaag aatggggcat attcatcttt ccgtcaagga tagtcgaaag tccagccagt
    33361 tttatcaaaa ggtgttaggg ctagaggata aattcagtgt gcctagcgct agttggattg
    33421 cggctggaga ttaccatcat catttagcag ttaacgaatg gggaggaaaa ggtctggctt
    33481 cgcgtaagca aggcttacca ggtttagcct actatgtcat cgaagtcgca cataaagaag
    33541 aactgttaac gattgtccaa cgagcacaag aagttgacgc accaatcaaa tggatgacat
    33601 cgagccaatt ggaaatcaca gactcagatg gcatcgtgac ccgtattcgt ttagcaaggt
    33661 aaaattagga atttctaata agttataagt attgctagtt tgctttttga acggtctttg
    33721 gtaacagaac tgcgtgagct ggatgggtga gaattttgac aaagaagctg attagagata
    33781 taatgaagaa aaatcgagca aggaaaaaga aatgacaaat tcaaagtata ttacttgttt
    33841 gaaacgttca gagggccagt tgtgtgggat tcaaaagatg attgaaggag atcgtgactg
    33901 tgctgatatt gtgacgcaac tgacagcagt gagatctagt gtagagcgcg tgattgagat
    33961 gataattacc gaaaatctta ctgaatgtat caatcagcca ctagatgatt ctgaagctca
    34021 aaaggaacgc ctagaaaagg ctatccgata cttgattaaa cggaaataaa tgaatgtttt
    34081 gagacgatat gtgcaaaggt ctattaacta ttagaatagt ttaatgtgag tcaaaagaag
    34141 ttgtaaaaaa tctttaaaat taaaaaaacg catagtatca ggtgttgaat gtactgaccc
    34201 ccaaaagtta gattttttct gtctaacttt tgggggtcag ttcataagaa ccttggtaat
    34261 atgcgtttta ttatgtagaa acttatactc ttcgaaaatc tcttcaaacc acatcagctt
    34321 caccttgccg tagatatggt tactgacttc gtcagttcta tccacaacct caaaacagtg
    34381 ttttgagctg acttcgtcag ttccatccac aaccttaaaa cagtgttttg agcagcctgc
    34441 ggctaacttc ctagtttgca ctttaatttt cattgagtat tacttcatct tctcatgaaa
    34501 ttgagttttt gcccagctcc tcttgattat tctacttgac cgggccaagt attcatacca
    34561 ccttctacgt tggtaacggt gaggccttgg gagctgagaa attggcaggt agatgcagag
    34621 cggactcctc cttgacaaat aacatagtat tcatggtcag gtttgagttc tttgtagcct
    34681 tgctctaagg tacttaatgg aagatttttg gcacctggtg catgtcctgc ttggaattca
    34741 tgtgcttcac ggacatcgat aagttctaga ttttcatttt agtattttcc ataaaagtca
    34801 gccatgctga tactagtttc catattctac tccttctggg ttagccattt tgtatagtga
    34861 ataagcgccg tcaaggtttt ggacggtaaa tcctgcttgc ttgaggatag gctctgcgat
    34921 atagctgcgc aaaccactgt ggcagctgac gatgtaggct tgttttttgt ccagttcatc
    34981 agcttcctcc ttgacacttt gtcagttttt gatacaatag tacaaaatta gaggaggtgg
    35041 gctatgattc agaaacatgc gattcccatt ttagagtttg atgataatcc tcaggcggtt
    35101 atcatgccca atcacgaggg gttggatttg cagttgccaa agaagtgtgt ctatgctttt
    35161 ttaggtgagg agattgaccg ctatgcgagg gaagtagggg cgaactgtgt tggcgaattc
    35221 gtttctgcta ccaagaccta tccagtctat gtcatcaact acaagggtga ggaggtctgt
    35281 ctggctcagg ctcctgttgg ctccgctcca gcagcccagt ttatggattg gttgattggc
    35341 tatggtgtgg agcagattat ctctactggg acctgtggtg tcctagctga tatagaggaa
    35401 aatgcctttc tagtccctgt tcgcgctttg cgagatgagg gagccagtta ccactatgtg
    35461 gcaccttgtc gttatatgga aatgcagcca gaggctattg ctgctattga ggaagttttg
    35521 gaagacagag ggattcctta tgaagaagtc atgacctgga cgacagacgg tttttaccga
    35581 gaaacggctg aaaaggtggc ttatcgtaag gaagaaggct gtgctgttgt ggagatggag
    35641 tgttctgctc ttgcggcagt agctcaattg cgtggggttc tctggggtga attgttgttc
    35701 acagcagatt ctctagcgga cttggaccag tacgacagtc gtgactgggg ctcggaagct
    35761 tttaataagg cgctagaact gagtttagca agtgttcacc acctttagtt gtacaggcaa
    35821 aggatttgtt ttatcataaa atgtctagct catacttttc aaaaatatgt ttaaacgagg
    35881 tcaccttcct cttgtcctag gcatgttgag gttgggaaaa atctttaaaa tcagaaaaac
    35941 gtatcatatc aggtgatgaa aattttgata ctatgcgttt tatgttggta agatttagag
    36001 tgagatgaaa tgatactctt cgaaaatctc ttcaaaccag gtcagcttca ccttgccgta
    36061 ggtatatgtt actgacttcg tcagtcttat ccggcaacct caaaacggtg ttttgagctg
    36121 acttcgtcag ttctatccac aacctcaaaa cagtgttttg agcaacctgt gactagcttt
    36181 ctaagcgatg ccttggttct cattgcctat aatcaaaaag agaaattttc tcctgaaaag
    36241 catatagagt agctggcgtt aaaagctcct gtcttgcttt tttgacctat agtcacatct
    36301 atcaagtatt gttcttgcct aagctatcaa taaaaaggtg gcatttttta ggcttggtgt
    36361 tagtgaattt tgccttatcc tatctaagtc atttcgagct ttttatggta caatggaaac
    36421 atgttattca aattatctaa ggaaaaaata gagctaggct tatctcgttt atcgccagcc
    36481 cgtcgtattt ttttgagttt tgccttggtc attttactag gctctcttct tttgagcttg
    36541 ccctttgtcc aagttgaaag ctcacgagcg acttattttg atcatctttt cactgctgtc
    36601 tctgcagtct gtgtgacagg tctctcaacc cttccagtag ctcacaccta taatatctgg
    36661 ggccaaataa tctgtttgct cttgattcag atcggtggtc tagggctcat gacttttatt
    36721 ggggttttct atatccagag caagcaaaag cttagtcttc gtagccgtgc aactattcag
    36781 gatagtttta gttatggaga aactcgatct ttgagaaagt ttgtctattc tatttttctc
    36841 acgacctttt tggttgagag cttgggagct attttgctta gttttcgcct tattcctcaa
    36901 cttggctggg gacgtggtct ttttagttcc atttttctag cgatctcagc cttctgtaat
    36961 gccggttttg ataatttagg gagcaccagt ttatttgctt ttcagaccga tttactggtc
    37021 aatctggtga ttgcaggctt gattattaca ggcggccttg gttttatggt ctggtttgat
    37081 ttggctggtc atgtaggaag aaagaaaaaa ggacgtctgc actttcatac gaagcttgta
    37141 ctattgttga ctataggttt gttgttattt ggaacggcaa ctactctctt tcttgagtgg
    37201 aacaatgctg gaacgattgg caatctccct gttgccgata aggttttagt tagctttttt
    37261 caaacagtga cgatgcgaac agctggcttt tctacgatag attatactca ggctcatcct
    37321 gtgactcttt tgatttatat cttacagatg tttctaggtg gggcacctgg aggaacagct
    37381 gggggactca agattacgac attttttgtc ctcttggtct ttgcacgaag tgagcttcta
    37441 ggcttgcctc atgccaatgt tgcgagacga acgattgcgt cgcgaacggt tcaaaaatcc
    37501 tttagtgtct ttattatctt tttgatgagc ttcttgatag gattgattct gctagggata
    37561 acagccaaag gcaatcctcc ctttatccac ctcatatttg aaaccatttc agctcttagt
    37621 acagttggtg taacggcaaa tctgactcct gaccttggga aattggctct cagtgttatc
    37681 atgccactta tgtttatggg acgaattggt cccttgacct tgtttgttag cttggcagat
    37741 taccatccag aaaagaaaga tatgattcac tatatgaaag cagatattag tattggttaa
    37801 gaaaggaaag agcatgtcag atcgtacgat tggaattttg ggtttgggaa tttttgggag
    37861 cagtgtccta gctgccctag ccaagcagga tatgaatatt atcgctattg atgaccacgc
    37921 agagcgcatc aatcagtttg agccagtttt ggcgcgtgga gtgattggtg acatcacaga
    37981 tgaagaatta ttgagatcag cagggattga tacctgcgat accgttgtag tcgcgacagg
    38041 tgaaaatctg gagtcgagtg tgcttgcggt tatgcactgt aagagtttgg gggtaccgac
    38101 tgttattgct aaggtcaaaa gtcagaccgc taagaaagtg ctagaaaaga ttggagctga
    38161 ctcggttatc tcgccagagt atgaaatggg gcagtctcta gcacagacca ttcttttcca
    38221 taatagtgtt gatgtctttc agttggataa aaatgtgtct atcgtggaga tgaaaattcc
    38281 tcagtcttgg gcaggtcaaa gtctgagtaa attagacctc cgtggcaaat acaatctgaa
    38341 tattttgggt ttccgagagc aggaaaattc cccattggat gttgaatttg gaccagatga
    38401 cctcttgaaa gcagatacct atattttggc agtcatcaac aaccagtatt tggataccct
    38461 agtagcattg aattcgtaaa gagggatgac ccctcttttt tgatgcccaa gatggcaaat
    38521 agagacagaa gccccttgtc ttctagtaaa agttcttcaa aggctggact ttatggtaaa
    38581 atagaaggaa gtgacaagag agagtaatac tcaatgaaaa tcaaagatca aactaggaaa
    38641 ctagctgcgg gctgctcaaa acactgtttt gaggttgtgg atagaactga cgaagtcagc
    38701 tcaaaacact gttttgaggt tgcagataga actgacgaag tcagtaacat ctatacggca
    38761 aggcgacgtt gacgcggttt gaagagattt tcgaagagta taagaaaaaa tcagtcccct
    38821 aaaggagcag attatgaagt tattgtctat cgccatttct agctataatg cagcagccta
    38881 tcttcattac tgtgtggagt cgctagtgat tggtggtgag caagttggga ttttgattat
    38941 caatgacggg tctcaggatc agactcagga aatcgctgag tgtttagcta gcaagtatcc
    39001 taatatcgtt agagccatct atcaggaaaa taaatgccat ggcggtgcgg tcaatcgtgg
    39061 cttggcagag gcttctgggc gctattttaa agtagttgac agtgatgact gggtggatcc
    39121 tcgtgcctac ttgaaaattc ttgaaacctt gcaggaactt gagagcaaag gtcaagaggt
    39181 ggatgtcttt gtgaccaatt ttgtctatga aaaggaaggg cagtctcgta agaagagtat
    39241 gagttacgat tcagtcttgc ctgttcggca gatttttggc tgggaccagg tcggaaattt
    39301 ctccaaaggc cagtatacca tgatgcactc gctgatttat cggacagatt tgttgcgtgc
    39361 tagccagttc taactgcctg aacatacttt ttatgtcgat aatctctttg tctttacgcc
    39421 ccttcagcag gtcaagacca tgtactatct gcctgtcgat ttctatcgtt atttgattgg
    39481 gcgtgaggac cagtctgtca atgagcaagt gatgattaag tgcattgacc agcaactcaa
    39541 ggtcaatcga ctcttgatag accaacttga tttgtcccaa gtgagtcatc ccaaaatgcg
    39601 agaatatctg ctgaatcata ttgaactcac gacggtgatt tccagtaccc tgctcaaccg
    39661 atctggaaca gcggagcatc tggcaaaaaa acgccaattg tggacctata ttcagcagaa
    39721 aaatccagaa gtctttcagg ctattcgtaa gaccatgttg agccgtttga ccaaacattc
    39781 tgtcttgcca gatcgcaaac tgtccaatgt cgtctatcaa atcaccaaat ctgtttatgg
    39841 atttaattaa tataagtgtt ttataagagg gatttaagaa aaattttaac tttttcttag
    39901 tcctttttaa tttcaggaga ttatactaga gtcatcaaat aaagaaagac tctaaggaga
    39961 atcctatgaa attcaatcca aatcaaagat atactcgttg gtctattcgc cgtctcagtg
    40021 tcggtgttgc ctcagttgtt gtggctagtg gcttctttgt cctagttggt cagccaagtt
    40081 ctgtacgtgc cgatgggctc aatccaaccc caggtcaagt cttacctgaa gagacaccgg
    40141 gaacgaaaga gggtgactta tcagaaaaac caggagacac cgttctcact caagcgaaac
    40201 ctgagggcgt tactggaaat acgaattcac ttccgacacc tacagaaaga actgaagtga
    40261 gcgaggaaac aagcccttct agtctggata cactttttga aaaagatgaa gaagctcaaa
    40321 aaaatccaga gctaacagat gtcttaaaag aaactgtaga tacagctgat gtggatggga
    40381 cacaagcaag tccagcagaa actactcctg aacaagtaaa aggtggagtg aaagaaaata
    40441 caaaagacag catcgatgtt cctgctgctt atcttgaaaa agctgaaggg aaaggtcctt
    40501 tcactgccgg tgtaaaccaa gtaattcctt atgaactatt cgctggtgat ggtatgttaa
    40561 ctcgtctatt actaaaagct tcggataatg ctccttggtc tgacaatggt actgctaaaa
    40621 atcctgcttt acctcctctt gaaggattaa caaaagggaa atacttctat gaagtagact
    40681 taaatggcaa tactgttggt aaacaaggtc aagctttaat tgatcaactt cgcgctaatg
    40741 gtactcaaac ttataaagct actgttaaag tttacggaaa taaagacggt aaagctgact
    40801 tgactaatct agttgctact aaaaatgtag acatcaacat caatggatta gttgctaaag
    40861 aaacagttca aaaagccgtt gcagacaacg ttaaagacag tatcgatgtt ccagcagcct
    40921 acctagaaaa agccaagggt gaaggtccat tcacagcagg tgtcaaccat gtgattccat
    40981 acgaactctt cgcaggtgat ggcatgttga ctcgtctctt gctcaaggca tctgacaagg
    41041 caccatggtc agataacggc gacgctaaaa acccagccct atctccacta ggcgaaaacg
    41101 tgaagaccaa aggtca
//
LOCUS       DAVHLA010000012        39579 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVHLA010000012 DAVHLA010000000
VERSION     DAVHLA010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39579)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39579)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39579
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.012"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            <1..94
                     /locus_tag="VVO77_000773"
     CDS             <1..94
                     /locus_tag="VVO77_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEU5692820.1"
                     /translation="TWAHIKKHLKKVLPSCNTFYEALLSCSCFN"
     gene            250..588
                     /locus_tag="VVO77_000774"
     CDS             250..588
                     /locus_tag="VVO77_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HEU5692821.1"
                     /translation="MTLTIHVYYKGDGDSAIKFAREMLDSGLVKEIRNQKGNLKYEYF
                     LPIEKEGTILLIDQWINQETLDKHYQSKTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
     gene            778..2214
                     /locus_tag="VVO77_000775"
     CDS             778..2214
                     /locus_tag="VVO77_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEU5692822.1"
                     /translation="MTTFKDGFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITLGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSIAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPVTCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFTDQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMVHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKEVISSNGESVE"
     gene            2266..2505
                     /locus_tag="VVO77_000776"
     CDS             2266..2505
                     /locus_tag="VVO77_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET family sugar transporter"
                     /protein_id="HEU5692823.1"
                     /translation="MIGSIAAILTTFAFLPQVFRVVKTKDTGSIALGMYVMQVIGIAL
                     WLAHGIRIGDLPLILANSVSFLLSGIILFYKLKYK"
     gene            2635..2949
                     /locus_tag="VVO77_000777"
     CDS             2635..2949
                     /locus_tag="VVO77_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HEU5692824.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIAAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            3067..5046
                     /locus_tag="VVO77_000778"
     CDS             3067..5046
                     /locus_tag="VVO77_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEU5692825.1"
                     /translation="MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLK
                     LIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVF
                     ILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSG
                     EERDKRRFIINYFLENQFFKTIHCYVKFNFFAQTVPLEEFARIVLDECQEANLKLSDF
                     VLQNLVVHIALSVIRLKSGFEIKNIDCQMTDDAIERKVAQRILSKVREVTNQEFPVQE
                     IDYITLHLLAKSQQCQKNQKNISEEVLKKSLFKTFQNLGLDDMYNFSSDFQLIEGLIT
                     HLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVS
                     LHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQE
                     KLKGIDFIVSAVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMDQMQVSSYVQSSKINK
                     FENNSFRQYFSKENFLICTESDKVNLLEKMVESLSVGESNEFEQSLLYGIKQREELSS
                     VVFSEKIAVPHPIQPFGTEGKVSVAICKDSLLWDNQSSYVQLVFLLSPSIYGNEGLAT
                     VTKKIVSLTENDELQNQLISCNNFEDFINIFEKIK"
     gene            5056..5370
                     /locus_tag="VVO77_000779"
     CDS             5056..5370
                     /locus_tag="VVO77_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HEU5692826.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            5401..5907
                     /locus_tag="VVO77_000780"
     CDS             5401..5907
                     /locus_tag="VVO77_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692827.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LNQFISPSPIIIFPIMLIVFSILATIEQFKLYGNRKEKLGITLMFVRIQMLISIGLLV
                     LTWTSWFENLFPIFENNQVARLFVFVVLLLGLVLSLLDIRRIKKIYKRTDKAYQQFVQ
                     LEKNSLSL"
     gene            5987..7333
                     /gene="celB"
                     /locus_tag="VVO77_000781"
     CDS             5987..7333
                     /gene="celB"
                     /locus_tag="VVO77_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HEU5692828.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYMVANYATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNSLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVLIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDIFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            7713..7889
                     /locus_tag="VVO77_000782"
     CDS             7713..7889
                     /locus_tag="VVO77_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692829.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALSLGMT"
     gene            8291..10504
                     /locus_tag="VVO77_000783"
     CDS             8291..10504
                     /locus_tag="VVO77_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HEU5692830.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSRTGNFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEDEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(10726..11202)
                     /locus_tag="VVO77_000784"
     CDS             complement(10726..11202)
                     /locus_tag="VVO77_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEU5692831.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDHKSGPLGKRIEWNFAKFLIGRDGQVFERFSSKTNPKQIEEAIQTLL"
     gene            11425..14628
                     /locus_tag="VVO77_000785"
     CDS             11425..14628
                     /locus_tag="VVO77_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HEU5692832.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSTWVDQKNSSADASTRVIEAKDG
                     AITISSHEKLRAALHRMVPIEAKKKYKLRFKIKTDHKVGIAKVRIIEESGKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQPSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDIASVKNGILEPLKEGTTNVIVSKDGKE
                     VKKIPLKILASVKDAYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRTYLWEKFSNYKMSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKSGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDS
                     KKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            15008..15393
                     /gene="tnpA"
                     /locus_tag="VVO77_000786"
                     /pseudo
     CDS             15008..15393
                     /gene="tnpA"
                     /locus_tag="VVO77_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(15772..16401)
                     /locus_tag="VVO77_000787"
     CDS             complement(15772..16401)
                     /locus_tag="VVO77_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEU5692833.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSALSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYVTLR"
     gene            complement(16411..17412)
                     /locus_tag="VVO77_000788"
     CDS             complement(16411..17412)
                     /locus_tag="VVO77_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEU5692834.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITVAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(17443..18084)
                     /locus_tag="VVO77_000789"
     CDS             complement(17443..18084)
                     /locus_tag="VVO77_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEU5692835.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKGYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(18103..18918)
                     /locus_tag="VVO77_000790"
     CDS             complement(18103..18918)
                     /locus_tag="VVO77_000790"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEU5692836.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            19189..19623
                     /locus_tag="VVO77_000791"
     CDS             19189..19623
                     /locus_tag="VVO77_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU5692837.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAARGGVVNGKELFSTDAEEEEEDFESGI"
     gene            19635..20825
                     /locus_tag="VVO77_000792"
     CDS             19635..20825
                     /locus_tag="VVO77_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEU5692838.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSAQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            20836..21327
                     /locus_tag="VVO77_000793"
     CDS             20836..21327
                     /locus_tag="VVO77_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEU5692839.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNATGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            21342..22121
                     /locus_tag="VVO77_000794"
     CDS             21342..22121
                     /locus_tag="VVO77_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU5692840.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            22108..22926
                     /locus_tag="VVO77_000795"
     CDS             22108..22926
                     /locus_tag="VVO77_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU5692841.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEVFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPTKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            22926..23219
                     /locus_tag="VVO77_000796"
     CDS             22926..23219
                     /locus_tag="VVO77_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEU5692842.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            23241..25142
                     /locus_tag="VVO77_000797"
     CDS             23241..25142
                     /locus_tag="VVO77_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEU5692843.1"
                     /translation="MKEERRQFFERIDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYLVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSYYRAKYTLSNWGILQTIPMLAIYHFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYQELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     RRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHRRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIGVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            25202..26203
                     /locus_tag="VVO77_000798"
     CDS             25202..26203
                     /locus_tag="VVO77_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU5692844.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKKLNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(26313..26648)
                     /locus_tag="VVO77_000799"
     CDS             complement(26313..26648)
                     /locus_tag="VVO77_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692845.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(26659..26901)
                     /locus_tag="VVO77_000800"
     CDS             complement(26659..26901)
                     /locus_tag="VVO77_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692846.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(26917..27111)
                     /locus_tag="VVO77_000801"
     CDS             complement(26917..27111)
                     /locus_tag="VVO77_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU5692847.1"
                     /translation="MNRVKEFRKELGISQLELAKNIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            27277..28227
                     /gene="rsmH"
                     /locus_tag="VVO77_000802"
     CDS             27277..28227
                     /gene="rsmH"
                     /locus_tag="VVO77_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEU5692848.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNNYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DRKPKMELVSRKPILPSAEELEANNRSHSAKLRVVRKIHK"
     gene            28239..28556
                     /gene="ftsL"
                     /locus_tag="VVO77_000803"
     CDS             28239..28556
                     /gene="ftsL"
                     /locus_tag="VVO77_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEU5692849.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            28560..30812
                     /gene="pbpX"
                     /locus_tag="VVO77_000804"
     CDS             28560..30812
                     /gene="pbpX"
                     /locus_tag="VVO77_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HEU5692850.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            30814..31794
                     /locus_tag="VVO77_000805"
     CDS             30814..31794
                     /locus_tag="VVO77_000805"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEU5692851.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLFAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            32357..34462
                     /locus_tag="VVO77_000806"
     CDS             32357..34462
                     /locus_tag="VVO77_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU5692852.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRTTGQLPGNAETDVQMSQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFNILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEVVARAIRRNRAGFDEGNRPIGNFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            complement(34758..35240)
                     /locus_tag="VVO77_000807"
     CDS             complement(34758..35240)
                     /locus_tag="VVO77_000807"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEU5692853.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(35335..36819)
                     /locus_tag="VVO77_000808"
     CDS             complement(35335..36819)
                     /locus_tag="VVO77_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEU5692854.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPGGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMSERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            36972..38579
                     /locus_tag="VVO77_000809"
     CDS             36972..38579
                     /locus_tag="VVO77_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEU5692855.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENTDSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKELLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            38744..38911
                     /locus_tag="VVO77_000810"
     CDS             38744..38911
                     /locus_tag="VVO77_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HEU5692856.1"
                     /translation="MKKRILSAGLTFTSDLLLAACGQSGSDTKTYSSTFSGNPTTFNY
                     LLDYYADNIVN"
     gene            complement(38904..39579)
                     /locus_tag="VVO77_000811"
                     /pseudo
     CDS             complement(38904..39579)
                     /locus_tag="VVO77_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT        12368 a         6680 c         8584 g        11947 t
ORIGIN      
        1 aacatgggct catatcaaaa agcacctcaa aaaggtatta ccaagttgca atacctttta
       61 tgaggctctt ttgtcctgct cttgtttcaa ttgactataa atcgctataa gaaaaaatca
      121 ttttattggt ataaagaagt gattgaaagt aatggcgaaa cgttagataa ttagttcata
      181 aaaaacaagt ttagatcctc atctaaactt gtttttttaa aattgaagga tgattttgga
      241 ggatataaga tgacattgac tattcatgta tattataaag gtgatggaga tagtgcaata
      301 aagtttgcaa gagaaatgct tgatagtggc cttgttaaag aaattagaaa tcaaaaaggt
      361 aacttgaaat acgaatattt tttaccaatt gaaaaagagg gaactattct ccttattgat
      421 cagtggataa atcaagaaac tttagataaa cattatcaat caaagacaat gcagaaaatc
      481 ttagatttaa gaaaaaaata tcacttgcag atgcaagttg aacgttatat agaagatgat
      541 tctgggatgc cagaaagcga taagtcgttt atagacacag ggaattagaa ttattgtgag
      601 agtttttgta gtttgaaagt attgaaaatc gtaaagatat cattacgaga atacaagaag
      661 atattgttct atttccatta aaaattactt ctttccttaa caataaggaa aaagaatgcg
      721 ttttcatctt ttggtttaag gtttataata agagtatcaa agtcaggagg aaaaaagatg
      781 actactttta aagatggatt tttatggggt ggtgctgttg ctgctcatca acttgaaggt
      841 ggatggcaag aaggtggcaa gggaattagt gttgctgatg ttatgactgc tggtcgtcat
      901 ggagtagctc gtgaaattac tttgggagtt ttagagggta aatattatcc aaatcatgag
      961 gcgatagatt tttatcatcg ttataaagaa gacatagcac tttttgctga aatgggattc
     1021 aagtgcttcc gtacctctat tgcatggaca cgtatctttc caaaaggtga tgagttagag
     1081 ccgaatgaag aaggattaca gttttatgat aatctttttg atgaatgctt aaagaatggt
     1141 attgaacctg tcatcactct atctcatttt gaaatgcctt atcacttagt gaccgaatat
     1201 ggtggttgga aaaataggaa attgattgat ttctttgctc gttttgcaga agtcgtattt
     1261 aaacgttaca aagataaggt taaatattgg atgactttca atgaaatcaa taatcaagcg
     1321 aattatcagg aagattttgc accatttact aactcaggta ttgtatatga ggaaggtgat
     1381 aatagagaag caattatgta tcaagcagca cattacgaat tagttgcttc tgcacgagct
     1441 gtaaaaattg gtcatgagat taatccagat tttcaaatag gttgtatgat tgcgatgtgt
     1501 ccaatttatc cagttacttg caatcctaag gatatcttaa tggcaatgaa agctatgcag
     1561 aagcgttatt attttgctga tgtgcatgtt ttaggtaaat atcctgagca tattttcaag
     1621 tattgggaac gaaaaggtat ttcagttgat tttactgacc aggataaaga agatttactt
     1681 ggtgggactg tagattacat tggtttcagt tactatatgt cctttgctat agactctcat
     1741 cgtgaaaata atccttattt tgattatctt gaaacagaag atttagtgaa aaataattat
     1801 gttaaggctt ctgaatggga gtggcaaatt gatccagaag gtttacgtta tgcgttaaat
     1861 tggtttacag accactatca cttaccactc tttattgttg aaaatggttt tggagctata
     1921 gatcaagttg cagcagatgg tatggtacat gatgattata gaattgaata tctaggtgcc
     1981 catattcgtg aaatgaaaaa ggctgtagtt gaagatggtg ttgatttaat gggttatact
     2041 ccatggggat gtattgattt ggtttcagct ggtaccggtg aaatgcggaa acgttatggt
     2101 tttatttatg tagataaaga tgataatggg aagggaagtt ataatcgttc cccgaaaaaa
     2161 tcttttggct ggtataagga agttatttca tctaacggtg aatcagtaga atagtataaa
     2221 caaactgaga ttattctcag tttgtttagc atattgaggt gacatatgat tggaagtatt
     2281 gcagcaattt taacaacatt tgcattttta ccacaagttt ttcgtgtagt taagacaaag
     2341 gacacaggat ctattgctct aggtatgtat gttatgcaag ttattggtat tgcattgtgg
     2401 cttgctcatg gtattcgtat aggagacttg cctttgattt tagcaaatag tgtttcattt
     2461 ctactctcag gaataatttt attttataaa ttgaagtata aataattttt ttccatatca
     2521 tttaggaaaa tgagggaatt gtcattggaa acgctttatt ttataataaa aatagataac
     2581 aaataagcca acttagcaca gctttgattg gatttaagaa aaggagaaaa tattatggca
     2641 aaagctttaa ttatttgtgc agcaggaatg tcttcatcac ttatggcaca gaaaacaaca
     2701 gagtttctaa aaggaaaagg gaaagatatt gtagttgatg ctattagtgc tactgaagga
     2761 gggaaagcta tcgcagcagc agcttttgat ttgtatcttg tcagccctca aacaaaaatg
     2821 tactttaagc aatttgaaga ggctggttct aaagcaggaa aaccagttgt acaaatacct
     2881 cctcaagcct atattcctat tccaatggga attgaaaaaa tggctaattt gattcttgag
     2941 aatatttgat gaacacatga aatgtcaata aatatttaag ttaagataaa ttgttttgag
     3001 tttgatataa attgatttaa gtgtataata tgcttcaata tatgaaaaca tacgttttag
     3061 gagggaatga atgtgttaaa cattaaagag aaagatatcc ttcaattttt aataaaaaat
     3121 aaggaacgtt ttgttacaag caaagaactg gcagaatatt tatcctgttc agatagaact
     3181 gtccgtaatg tactgaaatt aattgagaag acaatgatta ttcaaggagt ccggttgatt
     3241 tcaaaacaag gtcaagggta tcaaatattt tttgagaatc aaggcgctta ccaggagttt
     3301 agacaaactt atgaactgga agaagactat acgaaaactg cggtttcaaa aggtgatgat
     3361 cgtttagtat ttatcttaaa taaattatta tttgagcaag ttccagttct ttttgatgat
     3421 ttagctgatg aactttacgt tagtcgttca acattatctc atgatttcag aaagatacga
     3481 gtgatgttat cagagtataa tttgtccatt gagagtaggg cgaataaagg agtttatgtc
     3541 tcaggcgagg aacgtgataa acgacgtttt atcataaatt atttcctaga gaatcaattt
     3601 tttaaaacaa tacattgcta tgtaaaattt aacttttttg ctcaaactgt tccattagaa
     3661 gaatttgcta gaattgtttt ggatgaatgc caagaggcca acctaaaact atctgatttt
     3721 gtactacaga atttagtagt tcacatagca ttgtctgtga ttcgtttaaa atccggattt
     3781 gaaataaaaa atatagactg tcagatgact gatgatgcaa tagagagaaa ggttgctcaa
     3841 agaattcttt ctaaagtaag agaagtaaca aatcaggaat ttccagttca ggaaatagac
     3901 tacattactt tgcatttgtt agctaagagt caacaatgtc aaaaaaatca gaagaatatt
     3961 tctgaagaag ttttaaaaaa atctttattt aaaacatttc agaatttagg attagatgat
     4021 atgtataact tttcttcaga tttccaacta attgaaggat tgataactca tctaatgaca
     4081 ctacaagtac gtttagaaag ccggattacc ttaaataacc ctttggtaga tgaaattaaa
     4141 cagaattata gtgatatatt ctttatgact agagaaattc ttgcaaatat ggacaagttc
     4201 ttggagtgga caatatcaga tgatgaagta gcatatgtaa gtcttcactt tttagctgct
     4261 atggaacgta gcaaagagag tactaagttt aatattcttg ctatttgtgc aacaggattt
     4321 ggtgcagccc aaatgttaag aaatcgtttg gaaacggagt ttgggaagcg agtagaagtt
     4381 gttgatgtaa taggctatta tgaattgaat caagaaaaac ttaaaggaat agattttata
     4441 gtgtcagctg ttgatttatc aaatctatat tttcaaattc cagtttttaa agttagtgtg
     4501 tttcttaaga gtgatgagat ggaaatgatt agaaaagcta tggatcagat gcaagtttct
     4561 agttatgtac aatcatcaaa gattaataaa tttgaaaaca acagctttag acagtatttt
     4621 agtaaagaaa attttttaat atgtactgaa tcagacaagg taaatttact tgaaaagatg
     4681 gttgagagtt tatctgttgg tgaatcaaat gagtttgaac aatctttact ttatggaatt
     4741 aaacagcgcg aagaattaag ttcagttgtt ttttctgaaa aaattgcagt tccgcatcct
     4801 attcagccct ttggtacaga gggaaaggtt tcggttgcaa tttgtaaaga ttcgttactc
     4861 tgggataatc aaagttcata tgtccagcta gtatttcttc tatctccatc aatatatggg
     4921 aacgaaggtt tggcaactgt gactaaaaag atagtctctc tgacagagaa tgatgaattg
     4981 caaaatcagc taatatcttg caataacttt gaagatttta ttaacatatt tgagaagata
     5041 aaataggagg ttcatatgaa tcaagaggaa ctgcaggttg cagcatttga aattattctg
     5101 cattcgggaa atgcaaggtc agaaatacat gaagcatttg caaaaatgag agaaggtagt
     5161 tttgatgatg cagaaagtaa attaaatcaa tcaaatgaga taattcttga agcgcatcat
     5221 gcacaaacca aactcttgca agaatacgca agtggagtgg aaattaaaat tgaaattatc
     5281 atggtacatg ctcaagacca tttaatgacc actatgacat tattagaagt agcaaaggaa
     5341 atgttagctc tttataagaa agttaactaa atatgtgttg ttatataagg aggaaatgat
     5401 atggataaaa aagaacgaca aaaaattgaa caacaacgtc gagagatggc tctaactaat
     5461 acttttttta atcgatatct tcttctacgt tattcaatag cactcttctt ttttgggaat
     5521 atttattggc ttttgaatca gtttattagt ccctcgccta ttattatttt ccccattatg
     5581 ctcatagtat tttctatttt agcaactatt gaacaattta aactttatgg aaataggaaa
     5641 gaaaagttgg gaataacact aatgtttgtt agaatacaaa tgcttatttc aataggatta
     5701 cttgttttaa cttggacaag ttggtttgag aatctttttc cgatttttga aaataaccaa
     5761 gtagcacgtt tatttgtttt tgtagttctt ctattaggtt tagttctgag tttgttagac
     5821 attagaagaa ttaaaaaaat ttataaacga acagataagg cttatcaaca atttgtccaa
     5881 ttggaaaaga actcacttag tttataatcc tgaactagta taatttgtat ttgaaactag
     5941 tctttaaaaa gtaaaaatta ttatgtttta ttaaggaggt ctatttatgg atcaacaaaa
     6001 cgggttgttt ggttttcttg aaaaccatgt tatgggacca atgggcaaac ttgctcagtt
     6061 taaagtagtg cgtgctatca cggctgcagg tatggctgct gtaccattta ctattgtagg
     6121 atcaatgttt ttggtattca gtattttgcc acaagctttc tcattttggc caattgtggc
     6181 agatattttc tctgcttcat ttgataaatt cacatcactt tacatggttg caaactatgc
     6241 gactatgggt tctctatctc tttatttcgt tctatcactt gcatatgaat tgacaaaaat
     6301 ttatgcagag gaggaagaac tcaatatgaa ttctcttaat ggtgccttgc tcgccttgat
     6361 ggcttttgtc atgacagtac cgcaaatcat ttttgatggt ggaatgatga agactgtgac
     6421 aagtctaaaa gaaggtgcag taattgcaga tggatgggca atgggaaatg gagtcgcacg
     6481 ttttggtaca acaggaattt ttaccgcaat cattatggca attgtgactg ttcttattta
     6541 tcgtatgtgt gttaaacata attgggttat taaaatgcct gaagctgttc cagaaggagt
     6601 ttctcgtgga tttaccgctt tggttccggg atttgttgtt gcatttgttg ttatctttat
     6661 caacggtctt cttgtagcaa tgggaacaga tatttttaaa gtcattgcaa ttccatttgg
     6721 ttttgtatcc aatctgacta attcgtggat tggtttaatg attatttatc tattgactca
     6781 actactttgg attgtaggta tccacggtgc gaacattgtt tttgcatttg ttagtccaat
     6841 tgctcttgct aacatggctg aaaatgctgc tggcgggcac ttcgctgttg caggtgaatt
     6901 ttctaatatg tttgtaattg caggtggttc tggtgcaact ttaggactat gtttatatat
     6961 tgcttttgcc tctaaatctg aacagcttaa agcaatagga cgagcatctg tagttccagc
     7021 cttatttaat attaatgaac cattaatttt tggattacct attatctata atccagcctt
     7081 ggctatacca tttattttag caccaatggt tactgctact atttattacg tagcgaattc
     7141 tctaaacttt attaagccaa ttatcgcaca ggttccatgg ccaactccag tagggattgg
     7201 agctttctta gggacagcag atcttcgagc tgtattagtt gctctagtat gtgcatttgc
     7261 agcattccta gtctatcttc cattcatccg tgtatatgat caaaaattgg tgaaagaaga
     7321 gcaaggtatc taataagtaa aaaagtatac tcgatgatag aatccatata gtttaaataa
     7381 tgagcgttaa cattagcagt gaagaggtct ttttaagata ttcttctctg ctttttcata
     7441 ttttttcgct atgtagagta tgaagcaaaa tagaaagtag ttcgaatagt tgataaacag
     7501 ggaattgctg ttatttaaaa aaaacaataa agtaaagtat gttatcgtag aatacgatac
     7561 aatagtaaaa aagcaaaaag aatgcgtttt atatttgggt ttgaggctta taaaatagga
     7621 taagcgtact gaaaacttag atatgacaaa caaaataaaa tttttaaaag ctacagagaa
     7681 acatggtata atgtatctaa aggaggtagc atatgtcctt agatatagat aaagaaaaga
     7741 tgacaatcat gggaatagct tttgaaaacc gatccgtttt taagagtgtt tggtatgctt
     7801 taagtacaaa tatgattgaa ggatggcgac ctacggttag tgatgttgaa aaattacgag
     7861 atgaagctct ttctctgggg atgacttaat gaagcgcaac tgttatgagt cttatgacta
     7921 tgttgatccg gataatttat ataccgatcc gggttcttca gttctaagaa ataagcagga
     7981 aggaaaaaag cacgcgagct tgaatatcgt atgattgcta gtaagagttt gaaattattt
     8041 atcaatccta tcttagttaa tagtttaaaa gtagtttgtt tcacaactgc ataagcttag
     8101 aaaagttgaa aagtgataac tctttaataa actcttggtt tgttaaaaga tattttgtcc
     8161 actacatttt tttcaattga ctattatttg tcatagatat aacagataga acattgcatt
     8221 cagaataatg aaaaacgcat caaaaatggt gcgttctgtt tttatgctac cataaaagga
     8281 ggaaaacaaa ttgaaaattt ttaagggaga gttttatcga atctctgtat taacagacaa
     8341 gctagtaagg ttagaatact ctcgaactgg aaattttgag gatagaacga cacaacttat
     8401 ctataataga gattttggcc aagtttcgtt agattatatc gagacatcaa atgtactaga
     8461 tattatgacg gactattttc atctgcactt taataaagga gaatttaacg ccgaaaattt
     8521 atttatagaa ttaaaaggaa attttgccgt atatggtagt cgctggtatt ttggtgaatc
     8581 tattgaaacg ttaaaaggaa cagctcggac tctggataag gcagatggag caatctcgtt
     8641 agaagatgga attattagcc gaaatggtat agccttattg gatgattctc aaggatttat
     8701 ttgggatgaa caatctggtt atattgagag agaaaatcaa attgacctgt atttctttgc
     8761 ctatgggcat gattatagag gagcaatcag agacttttac catttgactg gttcaacacc
     8821 cttgttgcca agatatgctt taggcaattg gtggagtaga tattggcctt atacgtcgga
     8881 tgaatacttg gatttaatag acagatttga aacagagaaa attccattat ctatcggtgt
     8941 gttagatatg gattggcata taactgacat tccagctcgt tttggaagtg gctggacagg
     9001 atatagttgg aatagaaact taataccaaa tccagaacag ttattgcaac aacttcatga
     9061 tagaaagtta aaactctcct taaatgtcca tcctgctgat gggatacggg cttatgaaga
     9121 agcttatcct caaatcgcaa aacggttggg gttaaatgta gaactagaag aacctgctat
     9181 ttttgatttt tttaatccct cttttaggga agcctacttt aaagatgttc attatgagct
     9241 agaaaagcag ggagtagatt tttggtggat tgactggcaa caagggacac aaggtatgct
     9301 agatccactt tggcttttaa accattatca ctatcaggat agttgtaaaa atgcagaagg
     9361 tggtttgatt ttatcaagat atgcaggtcc tggtagtcac cgctaccctg ttggtttttc
     9421 aggggacact attattagtt ggaattcctt aagatttcaa ccctatttta cagcgacagc
     9481 atctaatatc ggttatagtt ggtggagtca tgatatcggt ggacatatgt tgggggatta
     9541 tgacgaagag ctacaaacta gatggctaca gtttggtgtt tttagtccga ttactcgatt
     9601 acatagttct agaagtcctt ttaatagtaa agaaccttgg ttcttttcag aaacaacatc
     9661 taagattatg aagaaatacc ttcgtttgag acatcagatg attccctatc tatataccat
     9721 gaatgtaaag acacatgagg aaggtgcccc attaatcagt ccaatctatt atttctatcc
     9781 agagaatgat gagagctata atgttccaaa ccaatacttt tttggaacag aactgatggt
     9841 ggctcccatt gtagaaaaga tggatttgac attccaatct gcaaaagtag atgtatggtt
     9901 ccctgaagat gaatggtatg acttcttttc agagaaaaaa tacacaggtg gtgtgaagtt
     9961 aagtgtttat agggacatct cgactacgcc tgtgtttgca aaaagtggtg caatcattcc
    10021 cttggttggt tctgagatag gtatgggtgt tgatttacct gaggttgtag attggtatgt
    10081 attcccaggg aaacaacatt cttttgaaat gcttgaagat caaaatggtc aaagatataa
    10141 aacaagatta tcaatcgatt gggaaatggg aatggtagag ttagcattac aaggagattc
    10201 tagtatcgtt ccaagcaata gaaaacatag aattcatttt aaaggaacga atgtgtctat
    10261 aattgaattg ccaaataaga atgatacagc taaatttgaa tggaaagata ataaaaggac
    10321 atctttaaat gacgaagttt ttagactact aaagacagct tctcttccat atgaattaaa
    10381 agatagattg ttaaatcaat tcatcaatgc gaaaaactct catgacttaa tgaatatctt
    10441 gcatcatcag gataaggaat tgagagggcg tttgttggaa atgatattta ctagccaaaa
    10501 ctaattgaaa taattagaaa gtcatttgtt tagtgtatat gaagattctg tatggtattc
    10561 gttatcactg gtcacattga aaatgtgaaa taagcaccta caacatagac tttacaacac
    10621 ttcatgtttt atatcatggg gtgtttttct atttaagtca aagcccatca aaaaatctca
    10681 ctattcatca ggttaaagga aacctaatca tagtgagatt gtgaattata gtagagtttg
    10741 tatcgcctct tcaatttgtt ttgggtttgt ttttgaagaa aagcgttcaa agacttgccc
    10801 atcacgacca atgagaaact tagcgaaatt ccattcgatt cgttttccta gtgggccaga
    10861 tttatggtct tttaaccaga catagagagg gtctgcttcc ttaccgttga ccttaatctt
    10921 ggcaaaacgt gggaaggtgg tttgaaaatg taggctacag aaggcgttga tttcctctgc
    10981 gctgccgggt gcttgtccca taaactgatt gcaagggaaa tccaatattt caaagccctg
    11041 atcttgatag cgttcataga gttcttgaag tccctggtac tggggcgtta aaccacatcc
    11101 agtagcagtg ttgacaatca agagaacttt accacgatag ctatccaagg gagttgcttg
    11161 gttgttttgg ttcaaaacgg aaaaatcata aagtgaagtc atgagggcct cttttctttt
    11221 tctacattgt aacagttttt acttttttcg tcgagtcgga tggaagatat tgttgaagaa
    11281 taagccttca atatgataga aaccgtttac aaataacttt aaaaatggta tgatttaatt
    11341 aaaccggttt actttgttgc tataaatctc taatttgaga tttagttcct attgatttta
    11401 caatatgttt attggagtgt atacatgcaa acaaaaacaa agaagctcat tgtgagtttg
    11461 tcttcacttg ttttatcagg atttttatta aaccattata tgacagttgg agcggaagaa
    11521 acgactacga ataccattca gcaaagccag aaggaagttc agtatcagca aagggataca
    11581 aaaaatttag ttgaaaatgg tgattttggt cagacggagg acggaagcag tccgtggaca
    11641 ggaagcaaag ctcaggggtg gtcaacttgg gtagaccaga agaatagttc tgcagatgcc
    11701 tcaactcgag tcattgaggc taaggatggg gctatcacta tctcaagcca tgagaaatta
    11761 agggcagcgc ttcaccgtat ggttcctatt gaagctaaga aaaagtataa actgcgtttc
    11821 aagattaaaa cagatcataa agtcgggatt gccaaagttc gtatcattga ggaaagtggt
    11881 aaggacaagc gattgtggaa ttctgcaacg acgtcaggaa caaaggactg gcagaccatt
    11941 gaagcagact atagcccgac tttagatgtt gataaaatca agctggagtt attctatgaa
    12001 acaggaactg ggactgtttc ctttaaggat attgagctgg tagaggtagc agaccagcct
    12061 tctgaggatt ctcaaacaga taaacagctt gaggaaaaga ttgatttacc aattggaaaa
    12121 aaacatgttt tttctcttgc ggactatact tataaggtag aaaatcctga cattgcttca
    12181 gtcaaaaatg gaattttaga acctcttaag gaagggacaa ccaatgtcat tgtcagtaaa
    12241 gatggcaagg aagtgaaaaa gattcctttg aagattctag cctctgttaa ggatgcatac
    12301 acagaccgtt tggatgactg gaatggcatc atcgctggga atcaatacta tgattctaaa
    12361 aatgaacaga tggccaaatt aaaccaggaa ttggaaggaa aggtagctga tagcctatct
    12421 agtatttcaa gtcaggcgga ccgcacctat ttgtgggaaa aattttcaaa ttataaaatg
    12481 tctgcaaatc tgactgccac ttatcggaaa ttggaggaga tggccaagca agtgaccaat
    12541 ccttcttctc gttattatca agatgaaact gtcgttcgaa cagtcaggga ttccatggaa
    12601 tggatgcata aacatgtcta caatagtgaa aagagcattg ttgggaactg gtgggattat
    12661 gaaatcggta cacctcgtgc catcaacaat accttgtctc tgatgaaaga atacttctct
    12721 gatgaggaaa ttaaaaaata tacagatgtg attgaaaaat ttgtaccaga tcccgaacat
    12781 ttccgaaaga cgactgataa cccattcaag gctctaggtg gaaacttagt tgatatggga
    12841 agggtaaaag taatagctgg tttactgcgt aaggatgatc aagaaatttc ttctaccatt
    12901 cgctcgattg agcaagtgtt caagttggta gaccaaggtg aaggttttta tcaagatgga
    12961 tcctatatcg accacaccaa tgttgcctat acgggtgctt atgggaatgt tttgattgat
    13021 ggcctgtctc aactgttgcc agtcattcaa aagaccaaga atccaatcga taaagataaa
    13081 atgcaaacca tgtaccactg gattgataaa tcgtttgctc ctttgctggt gaatggagag
    13141 ctgatggata tgagtcgtgg acgctcgatc agtcgtgcaa atagcgaggg gcacgtggcc
    13201 gcagtagaag tactaagagg gattcaccga atagcggata tgtctgaagg agaaaccaaa
    13261 caacgtttgc agagtcttgt gaagaccatt gttcaatcgg atagttatta tgatgtcttt
    13321 aagaatttga agacttataa ggatatcagt ttgatgcaat ccttgttaag tgatgcagga
    13381 gtcgcaagtg ttccaagaac aagttaccta tctgccttta acaagatgga taaaacagcc
    13441 atgtacaatg cagagaaagg gtttggattt ggcttgtcac tcttttccag ccgtaccttg
    13501 aattacgaac acatgaacaa ggaaaataaa agtggttggt atacgagtga tgggatgttc
    13561 tatctttaca atggcgattt gagtcactat agcgatggct actggccaac agttaatcca
    13621 tataagatgc ctggtacaac agagacggat gctaagagag cggatagcga tacaggtaaa
    13681 gttttaccgt ctgctttcgt tggaacgagc aaactagatg atgccaatgc gacagcaacc
    13741 atggatttca ccaactggaa tcaaacattg actgctcata agagctggtt tatgctaaag
    13801 gataagattg cctttttagg aagcaatatc caaaacactt caacagatac tgctgcaact
    13861 acaattgacc agagaaaact ggaatcaagt aatccatata aagtctatgt caatgataaa
    13921 gaagcctccc ttacagaaca agaaaaggat tatcctgaaa cccaaagtgt ctttttagaa
    13981 tcgtccgatt cgaaaaagaa tattggttac tttttcttta agaagagttc aatcagtatg
    14041 agtaaggctt tgcaaaaggg agcctggaag gatatcaatg aaggacagtc agacaaggaa
    14101 gttgaaaatg aatttcttac tattagtcag gctcataagc aaaatggaga ttcttatggc
    14161 tatatgctca ttcctaacgt ggatcgtgcc accttcaatc aaatgataaa agagttagaa
    14221 agtagcctca tcgaaaataa cgaaaccctt cagtctgttt atgatgctaa acaaggagtt
    14281 tggggcattg tgaaatatga tgattctgtc tctactattt ccaaccaatt ccaagttttg
    14341 aaacgtggag tctataccat tcgaaaagaa ggggatgaat ataagattgc ctactataat
    14401 cctgaaaccc aggaatcagc tccagatcag gaagtcttta aaaagctaga gcaagcagct
    14461 cagccacaag tacagaattc aaaagaaaag gaaaaatctg aagaagaaaa gaaccattcg
    14521 gatcaaaaga atctccctca gacaggagaa ggtcagtcaa tcttggcaag tctagggttc
    14581 ttgctacttg gggcgtttta tttattccgt agaggaaaga acaactaatt tgttcatcat
    14641 ctagatgaat tacatgaaac tgtggaaaat agaaaaaatc cgaagaaggc caaatatctt
    14701 cggatttttc ttttaaaaag ggataagttg atacttatcc ttttttactt cattatgtga
    14761 ctatagcgtt ttgaaactag aataggacgt cataactgct aaaagatttc tataaattca
    14821 tttgattttc ctaatcaatt tgttcgtatc ctatttcact ccactatatt agtccgtctc
    14881 gctccgtgag gtgcgagaca aaacaaccac ccgctatgcg ggtgcgcgtc gaaggctata
    14941 ccaaaaaact ccaaacgcga tacaataaag gtgttcaatc caattgtaaa gcgaaaggag
    15001 aaaaaatatg gcacaaaaga ctcatagttt atcatacaca aagtggatgt gttctatcat
    15061 attgtgttca cccctaagta tagacgaaaa gtcatctata atcaatatag aagtagttta
    15121 ggcgaaatat ttcatcgctt gtgtggttat aaaggtgttg aaatgatcga gggtcactta
    15181 atgccagacc atgtacacat gttagtcagt attccactaa ggctaagtgt ttcgagtttc
    15241 atggggtatt taaaaggcaa aagtgcactc atgatgtttg acaaacacgc caatctcaag
    15301 tacaagtttg ggaatcggca tttctgggcg gaaggttatt atgtaagtac agtagggctt
    15361 aataaagcca cacttaagaa atatagtcaa gattaaagaa attatcgagt ggatgatttc
    15421 ttcacgagta tgaaaatttg agaacgagta aagtatgata tatagtaaaa tgaaataaga
    15481 acaggacaaa atcgatcagg acagtcaaat cgatttttaa caatgtttta gaagtagagg
    15541 tgtactattc cagtttcaat ctactatagc actagataaa ttgagtgtaa aagaatatga
    15601 ggatcccttt agggatagtg gtaagtaata ccaaagtctc ttaaagaggc aagtgacgag
    15661 tcaagagcaa taaggcttga acaacgtgaa agccagcgtc tttaggcgct ggctggtaat
    15721 ttgggcttat agctctggga taaaccaccc gtttgacggg tggttatgat tttatctgag
    15781 tgtaacatac tgttgggcaa tctcgctgat gcggtcaaag ttgccttggg aagcgagttt
    15841 attgagttcg ccaccaattc caacggcgtc tgcaccagca gcgaaccatt gagggatgtt
    15901 gtttagaccg actcctccgg ttaccattac ggaaacttgt gggatcggtg ccttgactgc
    15961 agagatatat gctggactga gagcactacc tgggaagagt ttgatgattt cactaccggc
    16021 ttcaagtgca gtcgtgatct ctgtgagggt aatacagcct ggaatgtacg gtgtgctgta
    16081 gagattgcac attttcgcag tttcagcatg gaaagatgga gaaacaacgt aatttgctcc
    16141 ggctagaatg gcatctctag cagttacggc atcaagcaca gtacctgcac cgatacaaac
    16201 actctgatcg tcctgataca agtctacaag ttccttgatg atttgtcctg catactgatt
    16261 ggtataggcg atttcaatag ctttgatacc gcccttgata caagcaatcg aggcttgcag
    16321 tccttcttcc tttgtatttc ctcgaatgac agcgacaatt ttctgttttt ttagttcaat
    16381 aatcgtatct gatttggtca tgtaattctc ctaacgaatg atatcttgtg catttgccag
    16441 taaattttca atactagttg cggaagtgga gagatggtct cctggaagag tgcatttgag
    16501 agttgcgctc gcaactgcaa agtcaatggt agtttttagg gaggaatgat ggagtagttg
    16561 gtaaagggca ccagatataa aggcatcccc gctaccaatt cgttgataga ctgcagtttt
    16621 tagttggaca gactcttcaa atcgttcttc cagagcatag gcttgataga catttttgtc
    16681 ttgctcatca ctagagcgga gggtatggaa aatggccttg aaaccatagg cttcttttaa
    16741 aagtcgcatg cgattttcca cctcttctag gctagcactg tctcttggaa acatctctag
    16801 attttggtca tcaatcatga gaggatcaat accgaagcaa tagtcagtaa aacgtgcaaa
    16861 cttagaaaat tcatacttgg cttctaggac tgaaatcatc tttgttctca gattgagatc
    16921 cattgaaacg acaattcctc ggcgcttggc ttcttccaag agtaggagaa ggatcgcacg
    16981 gacctcttga ccgatagcta cggtgattcc actaaaatga aaatggctaa tcccctgaaa
    17041 gagagaatcc atatctagca tgtttggccg aatctggctg atactcgtat gcttacgatc
    17101 gtagaaaact tcactttgac gacaaccaaa gccgttctcc aaatagtaga ggccgattcg
    17161 atcgccaagc cgacagattg aactggtatc gatttggtgc tgtttcaaga atgtgagaaa
    17221 acgatctcca atctcgttgg cagggagtgc ggtaaagact ttcgttgaga tacccagggc
    17281 ttgcaaatta caagcgatgt taatttctga tccgccaaaa taagtcgaac tggcaacatg
    17341 atcgccgata ctggtggcat ctaatggtga gattcgaatt aatggttcgc caaacagtaa
    17401 tattttcgtc atccattagt tcctttctgg tttagaatag ctttacttgg ctaatacttc
    17461 tttcaaataa gcagcgactt catcatcttg gcagttttca aagaagtatt cttggaaata
    17521 tttgccagag atggtgtctt tgaggaagtc ttggtcgatt gttttaagga tggtcatcaa
    17581 atcattgtgg gtgatttgtt tcacctcgtt taagatacga gcgttgcgtt gttcagggat
    17641 tacacgttct cttgggtagc caccgcccat ttcttcagca aataagcgtt caaacatcaa
    17701 tttgagggtc agttctgccc cccagccaaa tcctttggca taagggatag acaaggcgtt
    17761 accaccattg atttgagaat aaaggtaagc gtcagttggg tccactgcta gaccacagac
    17821 aacaccaggg aagctgttta aagcaagcat agcccctaca cccgtaccac agccggtaac
    17881 aacaaagtca actgcctttg tatttaaaag gatggcagcc attagtccgt tctgcacata
    17941 agttaattga ctttctcctt cttctccacg cataccatag ttaaataatt ggtagccttt
    18001 tttatctgtc gcttctttta gactatcgta aataatgtga ttcttgctag cttgactatt
    18061 ttcattgatt aatgcgattt tcataagatc ttctttctat ttttactcag gttgttttcc
    18121 gatgtaggct aagataccgc catctacata taggatgtgg ccattgacaa aattgctggc
    18181 atcactagcg agaaagacag cagggcccat caaatcttca ggatttcccc aacgtgcagc
    18241 aggtgttttt gcaatgatga actggtcaaa tgggtggcga gaaccatctt cttgcaactc
    18301 acgaagaggt gctgtttgag gagtggcaat ataacccggt ccaattccgt tacattggat
    18361 attggctcca ccgtattcag acgcaatgtt gcgggtcaac attttcaagc cccctttagc
    18421 agcagcataa gcgctaactg tttcacgtcc cagttcgctc atcatcgaac aaatattgat
    18481 aatctttcca tgccctttct ttatcataga aggaataact gcctttgaaa cgataaatgg
    18541 tgcgtttaag tcaatatcga tgaccttacg gaaatcagcg gcgctcattt cgcacattgg
    18601 aactcggcgg ataataccag cgttattaac gaggatgtca atgacaccaa cctcttgttc
    18661 gatttgcttg accatggctt ggataccgtc ctcgtctgtc acgtcacaga catatccatg
    18721 ggcttcgatg ccaacttcac gataagcttc aatcccttta ttgaccagat cttgattgat
    18781 atcgttaaag acaatagtag cgccggcttc agcgtaggat ttggcaatag caaatccaat
    18841 tccataagaa gcgccggtga tgagagcaat ttttcctttt aaagaaaact gctcaattga
    18901 gaatgatgta tttgtcattt gatacttcct ttcaaatttg ttaagacttc tctataacca
    18961 aattatattc tagtaaaccg gttttgtcaa taaataaata tttttattta taaaaagatt
    19021 tattttcctt aaaaatggaa tattttgaaa tttctgtcta ttaaaatgat taaaaagata
    19081 atgaaagcgc taatattttt ttaaaaaaac tattgacaag ataaaaataa aggattacaa
    19141 tggggaatat aaagtaaacc ggtaaaccta aacaagaaag gagaaaagat gaaaattgta
    19201 cttgtagggc atggacattt tgctacaggg atttatagtt ctttacaatt gattgcaggc
    19261 aatcaagaaa atgtggaggc aattgacttt gtggaaggaa tgtcagcaga tgaactcaag
    19321 caaaaaatct tacttgcaat ttcaaatgaa gaagaagttt taatcctaag tgatctcttg
    19381 ggaggatcgc cattcaaggt ttcttctacc ataatgggag aaaatccagc caaaacaatg
    19441 aatgttctct cgggtttgaa cttagccatg ttaatggaag cagtctttgc tagaatggct
    19501 catagctttg atgaggttgt taataaatca gtagtggcgg cccggggcgg agtcgtaaat
    19561 ggtaaagaat tgttttcaac ggatgcagag gaagaggaag aagatttcga atcgggtatt
    19621 taaagggtaa aagaatgata aaaaaggtta cgattgaaaa aataaaatcg cctgagcgct
    19681 tcttagaagt accacttctg acgaaagaag aagtcggcca ggcaatcgat aaggttattc
    19741 ggcagttaga actcaacctt gactatttca aggaagattt cccgacgcca gctacctttg
    19801 ataatgtcta tccaatcatg gataacacgg aatggaccaa tggtttctgg acaggagaac
    19861 tgtggttggc ttatgaatac agtcaacagg atgcatttaa aaacatcgct cataaaaatg
    19921 ttctttcttt cctggatcgt gtcaataaga gagtagaatt ggatcaccat gatctcggct
    19981 tcttgtacac accgtcttgt atggctgaat ataagataaa tggagatgga gaggctagag
    20041 aagcaacctt gaaagctgca gataagttga ttgaacgcta tcaagaaaaa ggtggtttta
    20101 ttcaagcttg gggagacttg ggcaagaaag agcattaccg tttgattatc gactgcttgc
    20161 tcaatatcca actcttattc tttgcttatc aagaaacagg cgatcaaaaa tactacgata
    20221 ttgcagaaag tcatttctat gcttcagcta ataatgtaat ccgtgatgac gcttcgtcct
    20281 tccacacctt ctattttgat cctgagacag gtcaaccctt taaaggtgta acgagacaag
    20341 ggtatagtga tgattcatgc tgggcacgtg gtcaatcatg gggagtctat ggtattcctt
    20401 tgacttatcg tcacttaaaa gacgagtcct gctttgactt gtttaagggt gtgaccaatt
    20461 atttcttgaa tcgtctgcca aaagatcatg tgtcctattg ggatttgatt tttaatgatg
    20521 gtagtgctca atcacgagat tcttcagcaa cagctatcgc cgtctgtggg attcatgaaa
    20581 tgctaaaaca tctcccagag gtggatgctg acaaagatat ttataaacat gctatgcatg
    20641 ccatgcttcg ttccttgatc gaacattatg caaatgatca atttacccct ggtgggacaa
    20701 gtctcctcca cggtgtgtac tcatggcatt caggtaaagg agtggatgaa ggcaatatct
    20761 ggggtgacta ctattaccta gaagccctta tccgtttcta caaagactgg aacctatatt
    20821 ggtaggagga gaaatatgac aatgccaaat attattatga cccgtatcga tgaacggttg
    20881 attcatgggc aaggacaact ttgggtaaaa tacctaggtt gtaatacggt cattgttgcc
    20941 aatgacgaag taagcacaga caagatgcag caaactctga tgaaaacagt tgtgccagac
    21001 tcagttgcca tgcgtttctt ccctttgcaa aaggtgattg atatcattca caaggctaat
    21061 cctgctcaaa cgatctttat cgttgtaaag gatgtgaagg acgctttaac cttggtagaa
    21121 ggtggtgtcc ctatcaaaga aatcaatatt gggaacattc acaatgctac tggtaaagag
    21181 caagtgacac gctccatctt cctgggtgaa gaggacaagg cggccctcaa ggaattgagc
    21241 caaactcatc aagtaacatt taatacgaaa acaactccaa caggaaatga tggagctgtt
    21301 caagtcaaca ttatggacta tatttaaaag aggagatcgt tatgtcgatt aatgtatttc
    21361 aagcgatttt aattggatta tggacagctt tctgttttag tggaatgctg ttaggaattt
    21421 acaccaatag atgtattgtt ctgtcatttg gtgtcggaat tattctaggt gatttgccta
    21481 ctgctcttgc aatgggagct attggtgaat tggcttatat gggattcggt gttggtgctg
    21541 gaggtactgt tccaccaaac ccaatcggac ctggtatctt tggtaccttg atggctatca
    21601 ctagtgctgg taaagtcagt ccagaagcgg ctcttgccct ctctactccg attgctgtgg
    21661 cgattcaatt cttacaaact ttcgcctaca ctgtacgtgc tggtgcgcct gaaacggcga
    21721 tgaagcactt gaaaaaccat aatttgaaga aattcaagtt cactctaaat gcaacaattt
    21781 ggttgtttgc ctttattgga tttaccttgg gttgcttggg tgccctttca atggatacct
    21841 tgttgaaact cgtagactac attccaccag tattgcttac aggtttgaca gttgctggta
    21901 aaatgctccc agctatcggt tttgcgatga tcttgtcagt gatggctaag aaagagttga
    21961 ttccctttgt cttgttggga tatgtttgtg cagcttatct aaacatccca acaattggta
    22021 ttgcaattgt aggtactatc tttgctttga ttgaatttta taacaagcca aaaacagcgg
    22081 atcatgtggt agaggaggaa gcacacgatg actggatcta acaaattaac aaaacgtgat
    22141 tatcttaaaa cgtctttgcg ggcattcttt tgtcaaaatg gatttaacta tagtaactat
    22201 caagggttgg gatatgccaa tgtgatgtat cctgctttga aaaaacacta tggagaggat
    22261 caggaagttt tctaccaagc cttggaagaa aactgtgaat tctataatac caacccacac
    22321 ttcctgcctt ttattaccag cttgcatctt gtaatgttgg aaaatggccg accaacaaaa
    22381 gaaacacgta gcatcaagat ggccttgatg ggaccattgg caggtattgg ggattctctt
    22441 tctcaattct gtttagctcc attgttctca accatcgcag cttcgtttgc tcaagaaggc
    22501 ttggttgtcg gtccaatctt gttcttcctt gcgatgaata cgattttaac agcgattaaa
    22561 ttgtcaactg gtctgtatgg atacaaacta ggaacaactg tgattgataa actaagcgaa
    22621 cagatggcaa cgatttctcg tattgccaat attatcggtg taaccgtaat tgctggtttg
    22681 gcagcgacat ctgttaagat tatggtgccg attacctttg ctgcagggga agttaaagca
    22741 gacgctaaac aaagtatcgt aagtattcag ggaatgcttg ataaggttgc tccagctctt
    22801 ctaccagccc tatttacact tttagtttac tacttgatca aagaaaagaa atggacaaca
    22861 tataaactcg ttattttaac agttatcatc ggaattatcg gaagctggct taagattata
    22921 gcttaatgga tacaacattg ttttatggaa tagtgattgt cttggcagtg agtccccttt
    22981 tactgtcaag ctttcattct attcgtcagc aaaagttgct tcgcaaacag atggagcaac
    23041 gacaagagta tttagcttct ttaacatctg gtgatgaagt gttgttattg tctggaattc
    23101 atggaaaaat catttctatc aaagatgact tggtctcctt gcagattgca aaaggtgtgg
    23161 tcatctatgt agaaaaggaa agtgtaatgg gaaagacaaa agaactgctt tttaagtagt
    23221 tctttttctg gtaatagata atgaaagaag aaagaagaca attttttgaa agaatcgatg
    23281 gaaaccaatg tcgtgattat atcttgtccc actgttcaaa agactatgag aaagtcaaga
    23341 gttcccttga acgcttgatg gacaatcgtt ttatgtttga tagtccttgg gatatggagc
    23401 cttgttcaaa aatccatcaa atccagccga tggtatggga tcaagtattt gaagatgatc
    23461 cagaatgggc ttatatgctc aatcgacaag aatatctctt gcagtttatg atagggtatc
    23521 tggtagaagg agataaggac tatattcaaa agtgcaagtt ctttctattt gattggattg
    23581 agcaggtgag agaattttct cctcaatcct tgatgactag aaccttggat acgggtattc
    23641 gttcctttac ttggttgaaa ctactcttgc ttctcttgaa atttgacttg ctagaggaga
    23701 aagaactaga gaaaattttg gtcagtctag aaaagcagat tgactttatg aaaagctact
    23761 atcgcgccaa gtacaccctt agtaactggg ggattttaca aacaattccg atgcttgcta
    23821 tctatcattt cttttcagat aagatggacc tagaagaagc ttaccatttt gcttcagagg
    23881 agttgaaaca gcaaattgag acacagattt taggagatgg aagccagttt gaacagtcga
    23941 ttctctatca tgtagaggtt tataaagcct tgctggattt gtgtctcttg cttccagact
    24001 tgcaagatag ttaccaagag ttgctggaaa agatggcgac ctatattcaa atgatgacag
    24061 gcttagatgg acgaactttg gcttttggtg atagcgattc tacagaaacg acagaaattt
    24121 tgagcctgtc tgctgtggtt ttgaacaagg aagaccttct taacggtctg gatgttaaag
    24181 ttgatttgct tagcctcttg ttcctggggc gagaaaaggt caagcgactg caggaatttg
    24241 aaaggagagc ttggcagcct aagtccatga tctttgaaga ctctggacat gtctgtatta
    24301 aggatgaaca tcgttatcta tttttcaaaa atggtccgct aggaagtgcc catagccata
    24361 gtgacgagaa tagtttttgc ttacagtatc aaggccaacc tattttcata gatgctgggc
    24421 gttattctta tcgggagata tatgaacgtt atctcttaaa gagtgcttgg agtcattcga
    24481 cctgcattgt agatgggaaa gctccggaaa gaatcacagg atcctgggaa tatgaatact
    24541 atcctcactc cctgttttgt caccataaag aaagggaggg agtgcattat attgaggggg
    24601 cttattggtc agcagaacct gatttgcctt atcttcacag aagaaaaatc ctcatgttgg
    24661 tagaggatgt ctggctcttg gtggatgaca tcaggtgtca aggtcagcat gaggcgttga
    24721 ctcagtttat ccttgacaag gatgtgacct atcaagatgg gaaaatcaat cagttgagac
    24781 tatggagtga agttgatttt gatttggaag ataccatcat ttctcctaaa tacaatgagc
    24841 ttgaaagaag tagcaaactc accaagcgcc aattctttga gaatcagatg ctggattata
    24901 ccatcattgc gcatgagagt tttgaaatca tccgtcattc tgtctaccag acagatgatc
    24961 gtgaagtgga aaatgctctg gcttttgaag tgaaaaatga cgaaacagac aagctgattc
    25021 tgttattaag cgaggatatt ggtgtaggtg aaaaattgtg cctcgttgac ggaacaaaaa
    25081 tgcgtggaaa atgtctagta tatgataaaa taaatgagag aatgattcgc ttgcagtgct
    25141 agaaataggc attttgaata gtgaacatgt tataataagt attagtagga ggtgttttag
    25201 attggagaag aaactgacca taaaagacat tgcggaaatg gctcagacct cgaaaacaac
    25261 cgtgtcattt tacctaaacg ggaaatatga aaaaatgtcc caagagacac gtgaaaagat
    25321 tgaaaaagtt attcatgaaa caaattacaa accgagcatt gttgcgcgta gcttaaactc
    25381 caaacgaaca aaattaatcg gtgttttgat cggtgatatt accaacagtt tctcaaacca
    25441 aattgttaag ggaattgagg atatcgccag ccagaatggc taccaggtaa tgataggaaa
    25501 tagtaattac agccaagaga gtgaggaccg gtatattgaa agcatgcttc tcttgggagt
    25561 agacggcttt attattcagc cgacctctaa tttccgaaaa tattctcgta tcatcgatga
    25621 gaaaaagaag aaaatggtct tttttgatag tcagctctat gaacaccgga ctagctgggt
    25681 taaaaccaat aactatgatg ccgtttatga catgacccag tcctgtatcg aaaaaggtta
    25741 tgaacatttt ctcttgatta cagcggatac gagtcgtttg agtactcgga ttgagcgggc
    25801 aagtggtttt gtggatgctt taacagatgc taatatgcgt cacgccagtc taaccattga
    25861 agataagcat acgaatttgg aacaaattaa ggaattttta caaaaagaaa tcgatcccga
    25921 tgaaaaaact ctggtattta tccctaactg ttgggcccta cctctagtct ttaccgttat
    25981 caaaaagttg aattataact tgccacaagt tgggttgatt ggttttgaca atacggagtg
    26041 gacttgcttt tcttctccaa gtgtttcgac gctggttcag ccctcctttg aggaaggaca
    26101 acaggctaca aagattttga ttgaccagat tgaaggccgc aatcaagaag aaaggcaaca
    26161 agtcttggat tgtagtgtga attggaaaga gtcgactttc taaaatgaag gaaaatgact
    26221 tgcaatctct gttaagaaat aaaataatcc cacctagaac aagctaggtg ggattatttg
    26281 cctatgaaat gagaaattat gggagcaagc tcctaaatca actgtttttg atctacttct
    26341 ttaactactt gataaaagtt atagaagtag gccaaacttg aaatgatggt tacgactagg
    26401 aatattgaaa atttccattg gacagggttg gttaaaagtt gtggaaagga tatgaggaga
    26461 aagaagaggg ctgcgttgag gacaggtatc cgttttgatt gtattttctc aagtccttta
    26521 ttgagcgcag gaagaaagag gagtaggagt agtaaaactg tatgagaaac agctcctgaa
    26581 ataagggcaa agaaaaggaa aatactgata aaaacatgaa tgatcagtag tctagctagt
    26641 gatttcataa ggtacctcct aatcctggtc ttttttagct cttgcaatac gaagtgagtc
    26701 gacaatatgt atcatcactc cgaaaaagaa agctcccagt atagttttaa aaatatgttt
    26761 tgtatttaga agagaactga taaaatttgg attttcactt gttagggtat caatgagtgg
    26821 aattataaaa aatatcactg ttccataaat cgaacctgct ttcagaccag gataacgtaa
    26881 ctgtttcttt tcttttttca tgagtttgct ccttttttaa aaatcttcct cccaaaagag
    26941 actgttgagg tcagtttgga ggctgcgggc gagattgaga cagagttcca aggttggatt
    27001 gtacttgtcg ttttcaatca tattgatagt ctgtctcgag acaccgatat tcttggcgag
    27061 ctcgagctgg gaaatgccca gttccttgcg aaattctttc acacgattca tctgttcttc
    27121 tttctgattt atgtcgtata tatttgacta tattatagtc ttttaaacat aaagtgtcaa
    27181 gtatttttga catatttttt gaagaaatag tagtctcctt gtcctatttg tctgacaagt
    27241 gcaagctggt cggatttgtg gtaaaataga taagatatga caaaagaatt tcatcatgta
    27301 acggtcttac tccacgaaac gattgatatg cttgacgtaa aacctgacgg tatctacgtt
    27361 gatgcgactt tgggtggagc aggccatagc gagtatttat taagtaaatt aagtgaaaaa
    27421 ggccatctct atgcctttga ccaggatcag aatgccattg acaatgcgca aaaacgcttg
    27481 gcaccttaca ttgagaaggg aatggtgacc tttatcaagg ataacttccg tcatttacag
    27541 gcacgtttgc gcgaagctgg tgttcaggaa attgatggaa tttgttatga cttgggagtg
    27601 tctagtcctc aattagacca gcgtgagcgt ggtttttctt ataaaaagga tgcgccactg
    27661 gacatgcgga tgaatcagga tgctagtctg acagcgtatg aagtggtgaa caattatgac
    27721 tatcatgact tggttcgtat tttcttcaag tatggagagg acaaattctc taaacagatt
    27781 gcgcgtaaga ttgagcaagc gcgtgaagtg aagccgattg agacaacgac tgagttagca
    27841 gagattatca agttggtcaa acctgccaag gaactcaaga agaagggtca tcctgctaag
    27901 cagattttcc aggctattcg aattgaagtc aatgatgaac tgggggcggc agatgagtcc
    27961 atccagcagg ctatggatat gttggctctg gatggtagaa tttcagtgat tacctttcat
    28021 tccttagaag accgcttgac taagcaattg ttcaaggaag cttcaacagt tgaagttcca
    28081 aaaggcttgc ctttcatccc agatgatcgc aagcccaaga tggaattggt gtcccgtaag
    28141 ccaatcttgc caagtgcgga agagttagaa gccaataacc gctcgcactc agccaagttg
    28201 cgcgtggtca gaaaaattca caagtaagag ggaaaaagat ggcagaaaaa atggaaaaaa
    28261 caggtcaaat actacagatg caacttaaac ggttttcgcg tgtggaaaaa gctttttact
    28321 tttccattgc tgtaaccact cttattgtag ccattagtat tatttttatg cagaccaagc
    28381 tcttgcaagt gcagaatgat ttgacaaaaa tcaatgcgca gatagaggaa aagaagaccg
    28441 aattggacga tgccaagcaa gaggtcaatg aactattacg tgcagaacgt ttgaaagaaa
    28501 ttgccaattc acacgatttg caattaaaca atgaaaatat tagaatagcg gagtaagata
    28561 tgaagtggac aaaaagagta atccgttatg cgaccaaaaa tcggaaatcg ccggctgaaa
    28621 acagacgcag agttggaaaa agtctgagtt tattatctgt ctttgttttt gccatttttt
    28681 tagtcaattt tgcggtcatt attgggacag gcactcgctt tggaacagat ttagcgaagg
    28741 aagctaagaa ggttcatcaa accacccgta cagttcctgc caaacgtggg actatttatg
    28801 accgaaatgg agtcccgatt gctgaggatg caacctccta taatgtctat gcggtcattg
    28861 atgagaacta taagtcagca acgggtaaga ttctttacgt agaaaaaaca caatttaaca
    28921 aggttgcaga ggtctttcat aagtatctgg acatggaaga atcctatgta agagagcaac
    28981 tctcgcaacc taatctcaag caagtttcct ttggagcaaa gggaaatggg attacctatg
    29041 ccaatatgat gtctatcaaa aaagaattgg aagctgcaga ggtcaagggg attgatttta
    29101 caaccagtcc caatcgtagt tacccaaacg gacaatttgc ttctagtttt atcggcctag
    29161 ctcagctcca tgaaaatgaa gatggaagca agagcttgct gggaacctct ggaatggaga
    29221 gttccttgaa cagtattctt gcagggacag acggcattat tacctatgaa aaggatcgtc
    29281 tgggtaatat tgtacccgga acagaacaag tttcccaacg aacgatggac ggtaaggatg
    29341 tttatacaac catttccagc cccctccagt cctttatgga aacccagatg gatgcttttc
    29401 aagagaaggt aaaaggaaag tacatgacag cgactttggt cagtgctaaa acaggggaaa
    29461 ttctggcaac aacgcaacga ccgacctttg atgcagatac aaaagaaggc attacagagg
    29521 actttgtttg gcgtgatatc ctttaccaaa gtaactatga gccaggttcc actatgaaag
    29581 tgatgatgtt ggctgctgct attgataata atacctttcc aggaggagaa gtctttaata
    29641 gtagtgagtt aaaaattgca gatgccacga ttcgagattg ggacgttaat gaaggattga
    29701 ctggtggcag aatgatgact ttttctcaag gttttgcaca ctcaagtaac gttgggatga
    29761 ccctccttga gcaaaagatg ggagatgcta cctggcttga ttatcttaat cgttttaaat
    29821 ttggtgttcc gacccgtttc ggtttgacgg atgagtatgc tggtcagctt cctgcggata
    29881 atattgtcaa cattgcgcaa agctcatttg gacaagggat ttcagtgacc cagacgcaaa
    29941 tgattcgtgc ctttacagct attgctaatg acggtgtcat gctggagcct aaatttatta
    30001 gtgccattta tgatccaaat gatcaaactg ctcggaaatc tcaaaaagaa attgtgggaa
    30061 atcctgtttc taaagatgca gctagtctaa ctcggactaa catggttttg gtagggacgg
    30121 atccggttta tggaaccatg tataaccaca gcacaggcaa gccaactgta actgttcctg
    30181 ggcaaaatgt agccctcaag tctggtacgg ctcagattgc tgacgagaaa aatggtggtt
    30241 atctagtcgg gttaaccgac tatattttct cggctgtatc gatgagtccg gctgaaaatc
    30301 ctgattttat cttgtatgtg acggtccaac aacctgaaca ttattcaggt attcagttgg
    30361 gagaatttgc caatcctatc ttggagcggg cttcagctat gaaagactct ctcaatcttc
    30421 aaacaacagc taaggctttg gagcaagtaa gtcaacaaag tccttatcct atgcccagtg
    30481 tcaaggatat ttcacctggt gatttagcag aagaattgcg tcgcaatctt gtacaaccca
    30541 tcgttgtggg aacaggaacg aagattaaaa acagttctgc tgaagaaggg aagaatcttg
    30601 ccccgaacca gcaagtcctt atcttatctg ataaagcaga ggaggttcca gatatgtatg
    30661 gttggacaaa ggagactgct gagacccttg ctaagtggct caatatagaa cttgaatttc
    30721 aaggctcggg ctctactgtg cagaagcaag atgttcgtgc taacacagct atcaaggaca
    30781 ttaaaaaaat tacattaact ttaggagact aatatgttta tttccatcag tgctggaatt
    30841 gtgacatttt tactaacttt agtaggaatt ccggccttta tccaatttta tagaaaggcg
    30901 caaattacag gccagcagat gcatgaggat gtcaaacagc atcaggcaaa agctgggact
    30961 cctacaatgg gaggtttggt tttcttgatt acttctgttt tggttgcttt ctttttcgcc
    31021 ctatttagta gccaattcag caataatgtg ggaatgattt tgttcatctt ggtcttgtat
    31081 ggcttggtcg gatttttaga tgactttctc aaggtctttc gtaaaatcaa tgaggggctt
    31141 aatcctaagc aaaaattagc tcttcagctt ctaggtggag ttatcttcta tcttttctat
    31201 gagcgcggtg gcgatatcct gtctgtcttt ggttatccag ttcatttggg atttttctat
    31261 attttcttcg ctcttttctg gctagtcggt ttttcaaacg cagtaaactt gacagacggt
    31321 gttgacggtt tagctagtat ttccgttgtg attagtttgt ttgcctatgg agttattgcc
    31381 tatgtgcaag gtcagatgga tattcttcta gtgattcttg ccatgattgg tggtttgctc
    31441 ggtttcttca tctttaacca taagcctgcc aaggtcttta tgggtgatgt gggaagtttg
    31501 gccctaggtg ggatgctggc agctatctct atggctctcc accaggaatg gactctcttg
    31561 attatcggaa ttgtgtatgt ttttgaaaca acttctgtta tgatgcaagt cagttatttc
    31621 aaactgacag gtggtaaacg tattttccgt atgacgcctg tacatcacca ttttgagctt
    31681 gggggattgt ctggtaaagg aaatccttgg agcgagtgga aggttgactt cttcttttgg
    31741 ggagttgggc ttctagcaag tctcctgacc ctcgcaattt tgtatttgat gtaagaatgg
    31801 caccctgatg tttcagggtg tttttgtgtt taaatacaca atgaaaatca aagaacaaac
    31861 tagaaagcta actttaggct gctcaaaata taatatattg aaactagaat agtacacctc
    31921 tacttctaaa acattgttag aaatcgattt gactgtcctg aacgatttat cctgttctta
    31981 tttcatttta ctatacagtt tcgaggttgt agataaggcg aagctgatgt ggtttgaaga
    32041 gattttcgaa gagataaaaa atattggtca attaaagtca aaatccttga ccttttctga
    32101 ctaatgtagt atattatgaa cgtaaggtaa atgaaagcct tactagaaca cttatttaaa
    32161 gtaaaataga aagaggtggg gtctatgttt aatctagaaa tcttcagaag taaagatggt
    32221 ctactcctgc ttgaaaaaga aaaaccagaa atagtacgta gggtagcggt ttagctagtc
    32281 taaatttttt aaaacaaagg tcaaagatag tcaatatcag taatcataac taagtaaaca
    32341 aaaagaggta aagaatatga ataacaactt taataatttt aataacatgg atgatttatt
    32401 taaccaattg atgggtggta tgcgaggata cagttctgaa aatcgccgtt acttaattaa
    32461 tgggcgcgaa gtcacacctg aggaatttgc tcactatcgt acgactggtc aattaccagg
    32521 aaatgcagaa actgatgtgc aaatgtcaca acaggcatca ggtatgaaac aagacggtgt
    32581 ccttgcaaaa ctaggtcgaa acttgacagc agaagcgcgt gagggtaagt tggatcctgt
    32641 tatcggacga aacaaggaaa ttcaagaaac atctgaaatc ctctcacgcc gcaccaagaa
    32701 caatcctgtt ttggtcggag atgcaggtgt tggtaagaca gcagttgtcg aaggtctagc
    32761 gcaagccatt gtgaacggag atgttcctgc tgctatcaag aacaaggaaa ttatttctat
    32821 tgatatctca ggtcttgagg ctggtactca ataccgtggt agctttgaag aaaatgtcca
    32881 aaacttagtc aatgaagtga aagaagcagg gaatattatc ctcttctttg atgaaattca
    32941 ccaaattctt ggtgctggta gcactggtgg agacagtggt tctaaaggac ttgcggatat
    33001 tctcaagcca gctctctctc gtggagaatt gacagtgatt ggggcaacaa ctcaagacga
    33061 ataccgtaac accatcttga agaatgctgc tcttgctcgt cgtttcaacg aagtgaaggt
    33121 caatgctcct tcagcagaga atacttttaa cattcttcaa ggcattcgtg acctctatca
    33181 acaacatcac aatgtcatct tgccagacga agtcttgaaa gcagcggtgg attattctgt
    33241 tcaatacatt cctcaacgta gcttgccaga taaggctatt gaccttgtcg atgtaacagc
    33301 tgctcacttg gcggctcaac atccagtaac agatgtgcat gctgttgaac gagaaatcga
    33361 aacggaaaaa gacaagcaag aaaaagcagt tgaagcagaa gattttgaag cagctctaaa
    33421 ctataaaaca cgcattgcag aattggaaaa gaaaatcgaa aaccacacag aagatatgaa
    33481 agtgactgca agtgtcaacg atgtggctga atctgtggaa cgaatgacag gtatcccagt
    33541 atcgcaaatg ggagcttcag atatcgaacg tttgaaagat atggctcatc gcttgcaaga
    33601 caaggtgatt ggtcaagata aggccgtaga agttgtagct cgtgctatcc gtcgtaaccg
    33661 tgctggtttt gatgaaggaa atcgcccaat cggcaacttc ctctttgtag ggtctactgg
    33721 ggttggtaag acggagcttg ctaagcaatt ggcactcgat atgtttggaa cccaggatgc
    33781 gattatccgt ttggatatgt ctgaatacag tgaccgcaca gctgtttcta agctaattgg
    33841 tacaacagca ggctatgtgg gttatgatga caatagcaat accttaacag aacgtgttcg
    33901 tcgcaatcca tactctatca ttctcttgga tgaaattgaa aaggctgacc ctcaagttat
    33961 tacccttctc ctccaagttc tagatgatgg tcgtttgaca gatggtcaag gaaatacagt
    34021 aaacttcaag aacactgtca ttattgcgac ctcaaatgct ggatttggct atgaagccaa
    34081 cttgacagaa gatgcggata aaccagaatt gatggaccgt ttgaaaccct tcttccgtcc
    34141 agaattcctc aaccgcttta atgcagtcat cgagttctca cacttgacta aggaagacct
    34201 ttctaagatt gtagatttga tgttggctga agttaaccaa accttggcta agaaagacat
    34261 tgacttggta gtcagtcaag cggctaaaga ttatatcaca gaagaaggtt acgacgaagt
    34321 catgggggtt cgtcctctcc gtcgagtggt tgaacaagaa attcgtgata aggtgacaga
    34381 cttccactta gatcatttag atgctaaaca tctggaagca gatatggaag atggcgtttt
    34441 ggttattcgt gagaaagcct aagatagaat tttgaggata aaaaagaagg agccagctga
    34501 aaaaaactgg ttccttttga ggtacgacgg gcatgtcgta cagtagaagt gtactattct
    34561 agtttcaatc cactatagta gctcagaagt cggtacttaa acgtgctata tcaaaaccag
    34621 tccttgaaaa acgtggattg gtttcgtgtt tggattatta ccttgaacga catgcgttaa
    34681 aagttagttg aaccgccgta tgccgaacgg cacgtacggt ggtgtgagag gggctagaga
    34741 ttatccccta ctcgatttta aatcacatga cgttcaaagg catcatctga aatcccttgt
    34801 tccaagatga gttttgccca ttctttagca gagaagaggc tgtggtcctt gtagtttccg
    34861 caagattcga tggttgtccc tgggacatct tcccaagtag tagtttcagc gatttccttg
    34921 agcgaatcct tgataacagc tgcgatttta gcactggtgt gacgtcccca cataatcatg
    34981 tggaagcctg tgcggcaacc aaatggtgaa cagtcaatca tgccgtcaat gcgggtacgg
    35041 atgagtttgg ctaagaggtg ctcgatagtg tgaaggccgg cagtagggat agagtcttcg
    35101 tttggttgca ccaagcgaat atcataattg gagatgatgt ctccttttgg tcctgtttct
    35161 tccccaatca agcgaacata gggtgctttg acaatggtgt ggtcaagttc aaaactttcg
    35221 acaataactt cttttgacat ggtaaatcct ttcagttttc ttctctcatt atatcataaa
    35281 ggttgttcct gagacagaga gaaaacctct ccgaggctag agaggttgaa atctttactt
    35341 acgatataag cggtcgtatt ggtagtatgg gtcaaaggtt acgttgatac ccagtttacg
    35401 aaggacattc ttgtcttcat cagtcaagat gatggttgag tgggcttcgc ttcctttgag
    35461 gttgcctagt tcttccatag cgcgggcagc atcaggattt tctgtagctg tgatagcaag
    35521 tgcaatcagg atttcatttg aatgaaggcg tggattgcgg ctaccgagat gatcgatttt
    35581 aagaccttgg attggcttaa caacttcagg ttcgattagt tttacttctt tagcgatgtc
    35641 agctgatttt ttgatggcgt tgatcaaggc agcggctgta ggaccaaaga gttctgagtt
    35701 cttaccagtg acgatttccc catttggcaa ttcaaaggct agggctggtc caccagtttc
    35761 ttctgctttt tggcgcgcaa cgacagcaac cttacggtct gcaggtgtga taccgaggtc
    35821 gttcatgagc aactcaattt tcttgacggc agcttcgcca actttttcag ctttgaagtc
    35881 aagaactgtt tgatagtaac ggcggatgat ttcttgttta gaagcttcga cagcggcctc
    35941 gtcatctgta atagcgaaac caaccatgtt gacacccata tctgtcggtg aagcgtatgg
    36001 tgattttccg agaatacgtt ccgacatgcg tttgagcact gggaagattt cgatatcacg
    36061 gttgtagttg acagtggttt ctccataggt ttgaagatgg aaggggtcaa tcatgttgac
    36121 atcatcaagg tcagctgtgg cagcttcata agccaagtta actggatgat gaaggggaag
    36181 attccaaaca gggaaggttt caaatttagc gtagccagat ttgatgccat tgatttggtc
    36241 gtggtacata ttggacatac acgttgccaa ttttccagaa ccgggtccag gagcggttac
    36301 gacaatcaag ttgcgactgg ttttgatgta gtcgtttttg cccatgcctc ctggggaaat
    36361 gatgtgatcc atatccgtag gatatccttt gattggataa tgaagataag aatcaattcc
    36421 gtttttctca agttggttgc ggaaggcatc tgcagcgggt tggccagcgt attgtgtaat
    36481 gacaacggaa ccaacaaaaa tccctaattc attgaatttg tcaatcaaac gaagaacttc
    36541 ttggtcataa gaaatgccta agtcgccacg tgctttggaa tgttcaatgt tgctagcatt
    36601 aatggcaatc acaacctcaa cctgctcttt caattcttgc aagagcttga ttttgttgtc
    36661 aggttcataa ccaggaagga cacgagcagc gtggaaatct tctaacattt taccgccaaa
    36721 ctctaagtag agcttgccgt caaattggtt aatgcgctcc aaaatatggt cgcgttgtaa
    36781 attcaaatac tgttcagaac taaaagcttg ttttttcatt tttttacctc tggactctat
    36841 tataataaaa aattggaagt taggaaacta cggagctaaa aaagaaatta aaaagattaa
    36901 gcaaacgctt gcacaaaatt ttaaaaagtg ctatcataga ctatagatta ttaaaataat
    36961 gaggtaaaca gatgcaagaa aaatggtggc ataatgccgt agtctatcaa gtctatccaa
    37021 agagttttat ggatagtaat ggagatggag ttggtgattt gccaggtatt accagtaagt
    37081 tggactatct agctaagtta ggaatcacag cgatttggct ttctcccgtt tatgacagcc
    37141 ctatggatga taatggctac gatattgctg attatcaagc gattgcggct atttttggaa
    37201 ccatggagga catggatcag ctgattgcag aagctaagaa gcgtgatatc cgtatcatca
    37261 tggacttggt ggtcaatcat acctcggatg agcatgcttg gtttgtcgaa gcctgtgaaa
    37321 atactgacag ccctgagcga gactactata tctggcgcga tgaacccaat gacctagatt
    37381 ctatctttag tgggtctgct tgggaatacg atgaaaagtc aggtcaatac tatctccact
    37441 ttttcagcaa gaaacagccg gatctcaact gggaaaatga aaaacttcgc cagaaaattt
    37501 atgagatgat gaacttctgg attgataaag gtattggtgg tttccgtatg gatgttattg
    37561 acatgattgg caaaattcct gacgagaagg tagtcaataa tggtcctatg ctccatccct
    37621 atctcaagga aatgaatcag gcgacctttg gagataagga gctcttgaca gtaggggaga
    37681 cttggggagc aacgccagag attgccaagc tctactctga tccaaagggg caagaattgt
    37741 ctatggtctt ccagtttgaa catatcggtc ttcagtatca ggaaggtcag cctaaatggc
    37801 actatcaaaa agagctgaat atcgctaagt taaaagaaat cttcaacaaa tggcagacag
    37861 agttaggagt tgaggacggc tggaattccc tcttctggaa caaccatgac ctccctcgta
    37921 ttgtctcaat ctggggaaat gaccaagaat accgcgaaaa atctgccaaa gcctttgcaa
    37981 tcttacttca tctcatgaga ggaactcctt atatctacca aggtgaggag attgggatga
    38041 ccaactatcc gtttgaaaca ctggatcaag tagaagatat tgaatccctc aactatgcgc
    38101 gtgaggctct tgaaaaaggt gttccgattg aagaaatcat ggacagtatc cgtgttattg
    38161 gacgtgacaa tgcccgtacc cctatgcaat gggacgagag caaaaacgct ggtttctcaa
    38221 caggtcaacc ttggttggcg gttaatccaa attacgagat gatcaacgtc caagaagcgc
    38281 tggcaaatcc agattctatt ttctatacct atcagaaact ggtccaaatt cgcaaggaga
    38341 atagctggct aattcgagct gactttgaat tgcttgatac ggctgataag gtctttgctt
    38401 atatacgtaa ggatggcgac cgtcgcttcc tagttgtggc taacttgtct aatgaagagc
    38461 aagacttgac agtagaagga aaagtcaaat ctgtcttgat tgaaaacacc ctagctcaag
    38521 aagtctttga aaaacaaatc ttagttccat gggatgcttt ctgtgtggaa ttactataaa
    38581 tattttttgc agaaaaattt aaaattgaaa tcgtataaaa acaagggagg actgtataaa
    38641 aggcagaaat cctttgtttt ttataaccaa ggtttataaa ccttcattct cgaaattcaa
    38701 ttaactttac aaattcccac tattaaggag aaagaagacg aacataaaga agcgtatcct
    38761 tagtgcaggc ctgactttta catctgattt gcttttagct gcttgcggcc aatcaggttc
    38821 agatacaaaa acttactcat caacctttag tggaaatcca actacattta actatctatt
    38881 agactattac gctgataata tagtcaattg aaacaagaac aggacaaaag agcctcataa
    38941 aaggtattgc aacttggtaa tacctttttg aggtgctttt tgatatgagc ccatgttttc
    39001 tcaataggat tgtactcagg cgagtaggga ggaagaggta aaagtttatg cccaaactct
    39061 tcacacaaga gttctagctt ccccattcta tggaatcttg cattatccat aataataacc
    39121 gatggtgtgg ttaatgttgg taagagaaac ttctgaaacc aagcttcaaa aaagtcgctc
    39181 gtcatcatct cttcgtaagt cattggagcg attaactcac cattcatttg ttagacctgc
    39241 aaccaaagaa atcctctgat atcttcttcc agatacttta cctcttctta actgaccttt
    39301 taatgagcga ccatattctc gatgaaaata agtatcgaat cctgtttcat caatctaaac
    39361 aggtgctagg tgctttaaac tattaaaatt cttaagaaat aaggctactt tttctgggtc
    39421 ttgttcatag taggtgtggt tctttttttc gagtgtagcc catagctttg agcgcatagt
    39481 ggatggtagt tggatgacag gcaaattcag aagctatttc agtcaaataa gcgtctggat
    39541 tattagtaag atagttttta agtctatctc tatcaactt
//
LOCUS       DAVHLA010000013        38274 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVHLA010000013 DAVHLA010000000
VERSION     DAVHLA010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38274)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38274)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38274
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.013"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(90..851)
                     /locus_tag="VVO77_000812"
     CDS             complement(90..851)
                     /locus_tag="VVO77_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEU5692857.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(884..1510)
                     /locus_tag="VVO77_000813"
     CDS             complement(884..1510)
                     /locus_tag="VVO77_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEU5692858.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(1526..1843)
                     /locus_tag="VVO77_000814"
     CDS             complement(1526..1843)
                     /locus_tag="VVO77_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEU5692859.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(1840..2139)
                     /locus_tag="VVO77_000815"
     CDS             complement(1840..2139)
                     /locus_tag="VVO77_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEU5692860.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLLGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(2424..2615)
                     /locus_tag="VVO77_000816"
     CDS             complement(2424..2615)
                     /locus_tag="VVO77_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HEU5692861.1"
                     /translation="MSYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGAMIANDWVKDNGK"
     gene            complement(2776..3450)
                     /locus_tag="VVO77_000817"
     CDS             complement(2776..3450)
                     /locus_tag="VVO77_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692862.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLAIIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLIIRGDVAFGKL
                     EIVYVK"
     gene            complement(3456..3902)
                     /locus_tag="VVO77_000818"
     CDS             complement(3456..3902)
                     /locus_tag="VVO77_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU5692863.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(4016..4519)
                     /locus_tag="VVO77_000819"
     CDS             complement(4016..4519)
                     /locus_tag="VVO77_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEU5692864.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVFIPATGFVILSLLRKKINAPRPYEEWDIKPLLDRDSPGQSM
                     PSRHVFSATIISMTCLHASLTVGFILLVLSALLGLVRVLGGVHYPKDVVVGYICGLAW
                     GVLFFLF"
     gene            complement(4516..4878)
                     /locus_tag="VVO77_000820"
     CDS             complement(4516..4878)
                     /locus_tag="VVO77_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HEU5692865.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGEAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(5004..6803)
                     /locus_tag="VVO77_000821"
                     /pseudo
     CDS             complement(5004..6803)
                     /locus_tag="VVO77_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
     gene            complement(6842..7291)
                     /locus_tag="VVO77_000822"
                     /pseudo
     CDS             complement(6842..7291)
                     /locus_tag="VVO77_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809294.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            complement(7415..8131)
                     /locus_tag="VVO77_000823"
     CDS             complement(7415..8131)
                     /locus_tag="VVO77_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU5692866.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(9012..10427)
                     /gene="ply"
                     /locus_tag="VVO77_000824"
     CDS             complement(9012..10427)
                     /gene="ply"
                     /locus_tag="VVO77_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEU5692867.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(10438..10770)
                     /locus_tag="VVO77_000825"
     CDS             complement(10438..10770)
                     /locus_tag="VVO77_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692868.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDHLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(10841..11449)
                     /locus_tag="VVO77_000826"
     CDS             complement(10841..11449)
                     /locus_tag="VVO77_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692869.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(11462..11920)
                     /locus_tag="VVO77_000827"
     CDS             complement(11462..11920)
                     /locus_tag="VVO77_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEU5692870.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            12045..12444
                     /locus_tag="VVO77_000828"
                     /pseudo
     CDS             12045..12444
                     /locus_tag="VVO77_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(13208..13468)
                     /locus_tag="VVO77_000829"
     CDS             complement(13208..13468)
                     /locus_tag="VVO77_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692871.1"
                     /translation="MRERSATGAQDLSKSIKKHLNDITRLTASLLGDEKLSAIISSSA
                     VKADMHRFVIELEPVKSTILQNDDISLDQNEIFEILKNFLDG"
     gene            complement(13527..14078)
                     /locus_tag="VVO77_000830"
     CDS             complement(13527..14078)
                     /locus_tag="VVO77_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692872.1"
                     /translation="MPANTKVIFQETFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNPEFPSMIELFSIL
                     PEYSLKKDGREIPLHFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            complement(14068..15058)
                     /locus_tag="VVO77_000831"
                     /pseudo
     CDS             complement(14068..15058)
                     /locus_tag="VVO77_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101214.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(15466..15891)
                     /locus_tag="VVO77_000832"
     CDS             complement(15466..15891)
                     /locus_tag="VVO77_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692873.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYLGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEAASISLA
                     KKHNGILGSNNLRDVKSYVKEFSLEYMTTGDILVEAFKA"
     gene            complement(16025..16402)
                     /locus_tag="VVO77_000833"
     CDS             complement(16025..16402)
                     /locus_tag="VVO77_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692874.1"
                     /translation="MYHLYYDEVKKSSVSLILIGEGDETERKADQFASYFLIFPSSLY
                     RMVEEIRENANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIE
                     TASRLGYDTSLYRPLSESKKKCY"
     gene            complement(16424..16630)
                     /locus_tag="VVO77_000834"
     CDS             complement(16424..16630)
                     /locus_tag="VVO77_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692875.1"
                     /translation="MDLSNKAPNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMSLGR"
     gene            complement(16617..16778)
                     /locus_tag="VVO77_000835"
     CDS             complement(16617..16778)
                     /locus_tag="VVO77_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU5692876.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(17156..18112)
                     /gene="lytA"
                     /locus_tag="VVO77_000836"
     CDS             complement(17156..18112)
                     /gene="lytA"
                     /locus_tag="VVO77_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEU5692877.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKYDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(18488..19858)
                     /locus_tag="VVO77_000837"
     CDS             complement(18488..19858)
                     /locus_tag="VVO77_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEU5692878.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     YIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            complement(20165..21331)
                     /gene="recA"
                     /locus_tag="VVO77_000838"
     CDS             complement(20165..21331)
                     /gene="recA"
                     /locus_tag="VVO77_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEU5692879.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVPLDLGDELEIEIEE"
     gene            complement(21386..22642)
                     /locus_tag="VVO77_000839"
     CDS             complement(21386..22642)
                     /locus_tag="VVO77_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEU5692880.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQEQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(22727..23743)
                     /locus_tag="VVO77_000840"
     CDS             complement(22727..23743)
                     /locus_tag="VVO77_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEU5692881.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNAERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(23751..24269)
                     /locus_tag="VVO77_000841"
     CDS             complement(23751..24269)
                     /locus_tag="VVO77_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU5692882.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQAGGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(24259..24702)
                     /gene="tsaE"
                     /locus_tag="VVO77_000842"
     CDS             complement(24259..24702)
                     /gene="tsaE"
                     /locus_tag="VVO77_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEU5692883.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(24788..25408)
                     /locus_tag="VVO77_000843"
     CDS             complement(24788..25408)
                     /locus_tag="VVO77_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692884.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(25791..26654)
                     /locus_tag="VVO77_000844"
     CDS             complement(25791..26654)
                     /locus_tag="VVO77_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU5692885.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEAKELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            27120..27344
                     /gene="pneA1"
                     /locus_tag="VVO77_000845"
     CDS             27120..27344
                     /gene="pneA1"
                     /locus_tag="VVO77_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit PneA1"
                     /protein_id="HEU5692886.1"
                     /translation="MTNFNSNEKFCGKSLKSLSADEMSLIYGASDGAEPRWTPTPIIL
                     KSAAASSKICISAAVSGIGGLVSYNNDCLG"
     gene            27351..27539
                     /gene="pneA2"
                     /locus_tag="VVO77_000846"
     CDS             27351..27539
                     /gene="pneA2"
                     /locus_tag="VVO77_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit PneA2"
                     /protein_id="HEU5692887.1"
                     /translation="MKNDFVIGKSLKELSLEEMQLVYGGTDGADPRSTIICSATLSFI
                     ASYLGSAQTRCGKDNKKK"
     gene            27656..30646
                     /gene="lanM"
                     /locus_tag="VVO77_000847"
     CDS             27656..30646
                     /gene="lanM"
                     /locus_tag="VVO77_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 lantipeptide synthetase LanM"
                     /protein_id="HEU5692888.1"
                     /translation="MKYKIKNVHKTLFIKERYQILSERNDNSLNNFSLNNWRSTMSII
                     SEKTFEEMLKLNNYNKKIFSNTVNYDYTEEQIRLYSEYAKNSEWYKFAEGSFEIFRKH
                     PQRINFKKDFSRILEPFIINLLKLINNYLENKEYEWIDKNGNIFSSLVFYLEDLIYPW
                     IVKPLVLEINSLREKGLLEGESEQQRYKYFITLFDKEENILNFYNKYPVLLRQISESC
                     LRFYTYFIEILSNLENDFSVLEEELGLRGKLNDIKFGKGDTHSQGKTVLILFFDDAKI
                     VYKPKNLIINNSLNTIAEYIRKVDEKIRIRIPRTIAYSDHSYEEFIDYLPLEQKKKLP
                     EYYYNFGVLLAFIYLFNGSDIHFENLISYGDMPVIIDFETMLQQPLFDDKTGQSLLDT
                     LFHRVTRTLLLPTEGVKREDGLDVEMSALTGNFKKDAFNGQVLINLNTDKVKFDIGKI
                     DFEGGKNLPVRDGDIEFDKYIKDFKKGFRDFYLIFEELNKTEEFKMLLKANLYGLKTR
                     VLFRDTNSYASVLSFLYHPDFYEEMLDREKALENLWSNKFSNQGIVASECEQMRLLDI
                     PIFYTDTNINEIYDDFGNHFISLHQFSGYDYFMKYLPNNNLENLEKQLDIIEIYFPSF
                     DQRKKGYKLNLSNRKKLPNESLVTILHNEVENIADSLVINNIYDEYPIWSIPVNFKGS
                     KWCLEQTGNDMYRGRAGILLFMYYVKLLKDKSSYTQLYNKMLSAIPPSVSLSKTTFGL
                     TGDIGYFIVLSIIEDYDTNTLACLNYIKSVLTELEKTDFASVSNKSDYINGLLPLINT
                     LVRYYRRGIEKERVLRLVLSLGDTLYNDVSERDNSNFGYSFGHGLSGVIFTLKNIYKV
                     TRLKKYKELILQLVPREKIKIHSLKWCSGEFGTLVNHPQSVPEGIVASLDNDTFCHGS
                     MAIINFYIDYMKEMDTSMELESLLCSVVMNKSKEGEYRIVQTSNFPDFSLYTGVTGIA
                     YTFLRYIALNQNDKKIVIPSLLEI"
     gene            30996..31700
                     /locus_tag="VVO77_000848"
     CDS             30996..31700
                     /locus_tag="VVO77_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HEU5692889.1"
                     /translation="MNKIFIYAGVRNHNSKTLEYTKRLSSIISSRNNVDISFRTPFNS
                     ELEISNSDSEELFKKGIDRQSNADDGGVIKKELLESDIIIISSPVYLQNVSVDTKNFI
                     ERIGGWSHLFRLAGKFVVTLDVAESNGSDNVSEYLRDIFSYMGGQILHQVSITNSLKD
                     IAEAQLMEATYKIEDVLEGKIKYKTTDYQERAYQTLKLILENYDSEHFEKMYWEKKRL
                     FEANSLEEWYYVENIK"
     gene            31681..32610
                     /locus_tag="VVO77_000849"
     CDS             31681..32610
                     /locus_tag="VVO77_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M50 family metallopeptidase"
                     /protein_id="HEU5692890.1"
                     /translation="MLKILNNSVIYLCLIPLLFLLLIIFPNDSLIYYFRLILISLISI
                     TLHELGHFLVGRCLSYKLEMLATPFFFYFRKKIYFKFPVLLAFGYCQMSNRNITNEKN
                     SDRNLVFYFFGGGGANLIVAILALLGFVPYASEFFILNIILFLVTVCLPIDGTDGNAI
                     REIVLYSKDSKTYQRFFANSLYNNPYITIDDFAKLTSKEKSFFSKFEKCLINLYFEVK
                     GEGSAFTIANHEVFDSNIQENIIHEYYKLLHKSSDWIIPQNLSLEEVVFTLSNYIYSK
                     NNKYLEKIKYLKKLVDFRQEEIIDFILNKEEVL"
     gene            32607..34715
                     /locus_tag="VVO77_000850"
     CDS             32607..34715
                     /locus_tag="VVO77_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HEU5692891.1"
                     /translation="MKIPMIYQMENSECGLACCAMILNYFKYEISLNELREIYPSSRS
                     GYSLLSISKVLGDFNISSHAFKASVRDLKPLSFPLICFWESSHFIILEKISKNKFYIL
                     DPAKGRQRMSISEFERHYSNIILTFKKLDSFMSRKDNKKSPVLKYFFKYRNKLGILFF
                     VTALLYVIQSLVPIANRYIIDTNFKDDSYSSRMLFTILFIFTVSFSLMYLLRQIYVAS
                     LKYIMDKEISYDFMKHLIYLPYSFYEKRTLGDILFRANSIVYIREILSNNFIAAILDL
                     LMIVVYAVVLFSFSKYMVIFLISLSLALSIVMYPIIKISKNLIDKNIKEKVNVQNITS
                     EVISKNSDIKLTGEEEFWINKWDNFNTKQLIIGRKLDIHLSIVSSITNVLQIILPVLT
                     LIVGVNIKTFEQLTLGQIVAISTVSPYFISPIISLSDNYIQLMLLKGYFLRIEDVFNT
                     KSELIPERVSQDIKFDKKIELKDIWYKYGLFDDYVLKGINVTIKKGETVAIVGESGSG
                     KSTLAKILLGLLEPNIGSIEVDGVEKEEIGQTLYRKIFGAVLQNSTLSYGTLRENLTF
                     GHFVSDEELMTNLNSIGLSNVVKSLPLGLETIIAEEGNNFSGGQQQMILLARCLLSKP
                     SVVVLDEATSSLDNLSQQITTSYLSEIGTTKILIAHRLDTIKSADKILVMHNGEIVEI
                     GTHRELLELGGIYKQLYSNN"
     gene            34739..36478
                     /locus_tag="VVO77_000851"
     CDS             34739..36478
                     /locus_tag="VVO77_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEU5692892.1"
                     /translation="MKIMKKKYWTLAILFFCLFNNSVTAQEIPKNLDGNITHTQTSES
                     FSESDEKQVDYSNKNQEEVDQNKFRIQIDKTELFVTTDKHLEKNCCKLELEPQINNDI
                     VNSESNNLLGEDNLDNKIKENVSHLDNRGGNIEHDKDNLESSIVRKYEWDIDKVTGGG
                     ESYKLYSKSNSKVSIAILDSGVDLQNTGLLKNLSNHSKNYVPNKGYLGKEEGEEGIIS
                     DIQDRLGHGTAVVAQIVGDNNINGVNPHVNINVYRIFGKSSASPDWIVKAIFDAVDDG
                     NDIINLSTGQYLMIDGEYEDGTNDFETFLKYKKAIDYANQKGVIIVAALGNDSLNVSN
                     QSDLLKLISSRKKVRKPGLVVDVPSYFSSTISVGGIDRLGNLSDFSNKGDSDAIYAPA
                     GSTLSLSELGLNNFINAEKYKEDWIFSATLGGYTYLYGNSFAAPKVSGAIAMIIDKYK
                     LKDQPYNYMFVKKILEETLPVKNGIKVLNIPNVLRYDLNMLQLEYKNEQSWDSFIDNV
                     NLIELEERIQTTIGIKQINTHNIITIAREGYSQNYLPNTSENTYNSLQVSLVGVLLLF
                     ISMVNILWAKKSK"
     gene            36529..37296
                     /locus_tag="VVO77_000852"
     CDS             36529..37296
                     /locus_tag="VVO77_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HEU5692893.1"
                     /translation="MSQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFEDDLTSRISSQD
                     ERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQSILFWIDAVQ
                     NYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVMLAGAVLGIAT
                     SILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLGFVASVFLQVE
                     IGVAFLVLLLFTGLSLLQLHVQMQKENKMSILVLKGG"
     gene            37298..37930
                     /locus_tag="VVO77_000853"
     CDS             37298..37930
                     /locus_tag="VVO77_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5692894.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLAYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
BASE COUNT        12297 a         7364 c         6539 g        12074 t
ORIGIN      
        1 tttattatac atattttctt cctcctactt atctattcgt aggaaatcaa aaaaagttac
       61 agaaatttgt aacttttcga ggaaatttct tattttttat gaatcatgaa acctgtcgcc
      121 tgttgattgg ccataatggt catatctgta atctgaacac ggcgaggctg actggtcaca
      181 tagactactg tgtctgcaat atcctgagct tgcaaggctt ctattccttg gtaaacggac
      241 gcagcccgct ctttatcacc atgaaaacga acagttgaga aatctgtttc gacaatccca
      301 ggctgaatgg ttgtcacctt gatatccgtt gcgatggtat caattcgcag tccatccgaa
      361 aaggtcttaa ccgcagcctt ggtagctgag taaacagcgg caccagcata ggcgtagatt
      421 cctgcggttg accccatatt gataatatga ccttgattga cttttatcat tgctggcaag
      481 aaacagcgag taaccgccat cagaccttta acattggtat ccaacatggt caacatatcc
      541 aactcctcat agtcttgata gggagccaag tcaagagcca gtccggcgtt gttgaccaag
      601 atatcaatcc tccctatcgt ttctagaata tcagagcaaa cagtcttcac catgaccata
      661 tccgtcacat ctagtggaaa agtccagacg gtttgatttg gaaagcttac tgcaaactcc
      721 gacttgagga tttctaatct gtctatccgt cgtcctgtta gaacgacatc ctcaccctgc
      781 tccagataag cacgcgcaat cgcttcaccg attcctgagg ttgctcccgt aatcactaca
      841 ttttttgcca tcttatttcc ttctatcaga tgctgacaag ttcctaggca gtccagtgtt
      901 tcgctgggtc gaacggtgtt ccgacaactt ggtcttctga taattcaagc accccacgtt
      961 tttgcggagc atttggcaaa tgcaattcac gaggactaca catcatccca aaactctttt
     1021 caccacgaag ttcgcctggg aaaatgaaat tcccttttgg catcatggca ccaggaagag
     1081 ccacaatggt tttcaaccca acacgcgcat taggtgctcc tgcaacgatt tgcactatct
     1141 tgtcacttgc gactgcaact tggcagatgt tgaggtggtc actgtctgga tgagctacca
     1201 tctcgacaat ttcaccaaca acaaacttag gttccttatc attaacaatt tcttctgtaa
     1261 aaccttccgc ctgtaattct tggttcaaac gagcgacttg ctcatctgat aaaaagactt
     1321 gaccgcgctc tgcaatttca aacaagctcg aaacctcaaa aatgttccaa gctactgttt
     1381 ccccattttc tttgaggaaa acacgggcta ccttgccttt gcgttccaca ttcagtttgg
     1441 catctccgct atttttcacg atgaccataa ggacatcacc gacatgttct ttgttatacg
     1501 taaaaatcat tgtttccttt ttctcctatt tcaatcctgc taaaaaatcg ttaatttgct
     1561 ccttactttt acggtcgcga ttgacaaaac gaccgatttc cttgtccttt tctagaacaa
     1621 caaggctagg aattccgtaa acatcccaga gtttggccaa atccatatac tgatctcggt
     1681 ccattcgaat aaaggtgaac tctggattgg tctcttcaat ctctggtaag gcaggataaa
     1741 tataacgaca atcgccacac cagtctgcca caaaaaggaa gaccttcttg cccgcttttt
     1801 ccactaaaga tgctaattct tctaaacttg ctggctgtat cataagactt cctcctcata
     1861 gactaggtct tcattttcat agacaaaggt ataatgacgg ccatcctcaa aaatgacgcc
     1921 accaagcaag ctctctagac tgctttcata gacttgaaca tagagggtcg caatttcccc
     1981 catgtctgaa aaatggtctc gcacaatctc tgtcaactct tcctgagtct tcatgagctt
     2041 acggtcatct gcaacttttt tcgtagcaag agcaaggctt ccgataccta gcagagccaa
     2101 gcctgccatc cacatttttt tagctttcat accattcatt ttaacacaaa aaaggcttca
     2161 ggacaaatga ggaagcagca gaaaagcaag taaaaagcct cttcctttaa ggaaaaggac
     2221 ttcttatact aagagcaaac tagaaagcta gccgcaggct gctcaaaaca cggttttgag
     2281 gttgtagata aggcgacgtt gacgtggttt gaagagattt tcaaagagta ttattcttat
     2341 tgccaggcac ctaagttgcc aacgtagtaa ccatcaggtg tgtaggtatt gcgaagcatc
     2401 ttacctgatg aagccagata atactacttg ccattgtctt tgacccaatc attcgcaatc
     2461 atggcaccag aagaacttac ataataccat tctcccttgt cataaaccca agtactgact
     2521 ttcatggttc ctgagcaatt aaaggcaaaa aaactgtcca atatcattcg ttttttaaaa
     2581 gcatttgaca ctacatcatc tacgctgtag gacatagatg catcaaacgt aaaagccaaa
     2641 atatcgaaaa atatacaact tttaaaggca gcatttcatt ttttaaagtc taacaaccat
     2701 agaactgaaa tcagagcaag gcatcaattt cctactctta gtacgtctat tttgatggtt
     2761 gaagtgaaga tttttttatt taacgtagac aatttccaac ttcccaaaag ccacatctcc
     2821 acggataatc aaggttttgc tggttggggc tacaggagcg tcagccttag ctgcaccaaa
     2881 ggaggtttct actttcaaat ctacacgcca gtgttgtgga acatagacgg ttgcatttcc
     2941 gaaggccact tcaatattta aagttgcaaa atcacctagc atctctgcat tatcatagta
     3001 gattttagca tccccaaaag cgacttccac ttggtcatct acgagatctt gatcttgctt
     3061 atagaaggtc ccgctaccaa aagcgacttc cttatccgtg acgactgttt ttttcccatt
     3121 gtaccaccat tttttttcat tccagaactt acttgaatgc gtcagataac caacaccaag
     3181 taccaccaag atgctagccc aaataagaga atgattggta actggtaaca agtcataagc
     3241 gtaatttgca atgatgatcg ccagtaaacc tgtaaaaact gccgaagtga gatgacgtct
     3301 aaggatggac tcaatggact tataagcaaa aaaaacaata cctagtaaag gccatatttt
     3361 accatccaaa gaaggaattc caaaattccc ttgcagcaag atccaagctg ctaaaaccaa
     3421 taaaacaata ccaaatgctt tctttttcat gttttttacc tcatgtttct tagattttct
     3481 tttaggaggg attggtaatg ccgtgagaca tgaacctcct tgtgcgtctg ataaaaggaa
     3541 atggtgcccg ttcctgaaaa ggacttgtcc actgagtaaa tctgacggat gtttgcgatc
     3601 gttgacttgg aaactcgatt aaaatagcga ggcaagatag actccaactc atagagcttg
     3661 aggcgaacct cataagcttc cttctggtta tgagcgtaga tcttgctccc ttctgtttca
     3721 aagaagagaa tttctgacag gtctagataa tattcacctg tccccttgta aaaagtcaac
     3781 ctcggagcct ttgactcttg caagagccgt tgcaagtctg caatttcatc tgtcaaagtg
     3841 ggggtcttga tgacaatttc agtctcctct aaattgccgt caatctcaat tcgtaacttc
     3901 atcacatctc ctttctgact ctactatatc aaagctaagt taggaataca agggcaaaaa
     3961 agcaagtggt caatttgaag cagtaagtgg ttgcaagacc aacttaactt acaggtcaaa
     4021 atagaaagaa aagcacaccc cacgcaagac cacaaatata accaactact acatccttgg
     4081 gataatgtac accacctaag actctcacga gaccgaggag ggctgacaag accaacaaga
     4141 taaagcccac agttagacta gcatgtaagc aagtcatgga gataatggtt gctgaaaaga
     4201 catgacgact gggcatagac tgaccaggac tatctctgtc aagcaagggt ttaatatccc
     4261 attcctcata aggcctaggg gcattgattt tcttacgaag aagggataaa atcacaaaac
     4321 ctgtagcagg gataaacaca taaaccccaa cttgctgacc aagtcctagt tgcaggtaag
     4381 tggtgactag caagatcaga tagaccaggg gcatggcgac tgtcatcaaa cgattgaaac
     4441 tgcgtaatag gaataaaaga attggacgac tagttagtct ggagctgata tttcgatacc
     4501 attcttgata atttttcatt tatgcttctc atacttttct agaacttgtt gagatgtttt
     4561 ccccttggca agccaatcca ctagcttgtc caagcgacgt atttcctgca tcagaggatc
     4621 atcaatttcc tcaatacgga caccgcaaat cttccctgta attgcaattc gttcagggac
     4681 ataatatggt gcttgtcgaa aaaaatctcc gtaagtaaca tccctatcca gacaagcaag
     4741 aacgtcactc acttcatacc ctgtcaacca actggtcact tggtgaactg actctgcctc
     4801 tccacccttt cgctcaactt ttgcaatcaa ggctaaatag acagcagcaa atttcatatt
     4861 gtataatttc tgactcatac ttctctcttt ctatgtgtac tagtataaat aagaaaaaga
     4921 aggccgtcaa gccttctttt gatttattct tctgcttcat cttctgtaaa ttgactattg
     4981 tacaagtcag cgtagaagcc accttacacc atcagttcct catagttgcc ttgctcgatg
     5041 atatttccat ctttcatgac caagatcaag tctgcatttc ggatggttga caagcggtgg
     5101 gcaatgacaa aggatgtgcg tccttccatc aaacggtcca tggctttttg gatcaattcc
     5161 tctgtccgtg tgtcaacaga agaagtcgcc tcatccaaaa tcaaaagcgg tgcatcctta
     5221 agaagggcac gagcaatagt caatagttgt ttttgtccta cagacaaggt cacggtgtca
     5281 tccaagatgg tatcatagcc atctggcaag gtcataataa agtggtgaat tcccacagcc
     5341 ttactagctt ccatcattcg ttcatcacta atccctattt gattatagat gagattgtct
     5401 cgaatagttc cttcaaagag ccaggtatcc tgcaagacca ttgaaaaggc atcatgcact
     5461 tctgaacgcg tcatagcctt ggtatccaca ccatcaatgc gaatacttcc cttatcaatc
     5521 tcatagaatt tcatcaaaag attgacaatg gttgtcttac cagccccagt cggcccaaca
     5581 atggcaaccc tttgaccagc atgagctgtc gcagagaagt catagtcttg aacattgaca
     5641 ccgtccacca gaatttctcc tgctgacacg tcgtagaaac gtggaatcag attgaccaga
     5701 gttgatttac cagaacctat tgacccaata aaggccactg tttgaccagt ttctgcttta
     5761 aagctaacat gttcaataac tgcctccgaa tttgccgcat agcggaaggt cacatcctta
     5821 aactcgacct gacctttgaa gttttcatca gtcagctgca cttgagcagg gttttggata
     5881 gaagaatgca aatctaaaac ttgattaatc cgcttagcag agaccatagt tcggggaaga
     5941 acgatgaaga gtgctcccat gagaaggaag tccatgacaa cctacatggc ataagacatg
     6001 aaaacaatca tgtcactaaa gagaggcaga cgcgctatcg gagcagcgtc gttaatcaca
     6061 taggccccaa tccagtaaat cgccacactc aaaccacttg aaatccccat catgatagga
     6121 ttcaaaatag ccataagacg gttgacaaac aaattttaac gggtcaattc atcatttact
     6181 gctgcaaatt tttcattttg ataatcctct gcattgtagg cacgaacgac acgaatacct
     6241 gttaaactct cacgagtgat actgttcagt ttatctgtca gcccctgaat caaggactgt
     6301 tttggaaagg ctagcgtcat caaaacggtc gtcatcagga cgttgacaat cactgccaca
     6361 agtacggccc agagccagta ttctgaatga cctaaaatct tcccaatagc ccagatagcc
     6421 ataattggac cacacgttac cacttgcaag tccatagtaa tcaacatttg aacttgagta
     6481 atgtcattgg tagtacgcat caagaggcta ggaattgaaa atttcttaat ctctgtctgc
     6541 gagtaatcca aaactcggtt aaaaatatca cttctcagcc tactagtata agaagccgcc
     6601 actcgggatg caaaaaatcc aactgcaact acggacaaga aggcaagaaa gggcattccc
     6661 atcatcatgc ttgccggctg ccacaactca tctaaattag tttcttgact acctagcaaa
     6721 tccgtaattt tcgagatata ggtcggcact tccaactcta gatagaccga aaagcaagta
     6781 aagagaatgg ctagtaaaat catcccccat tcttttctac taattctttt ggttaatttc
     6841 tttattctct cctcctattc ccttgatatt ttgcctgtag ttgaccgaga actttctcaa
     6901 aaatcagtaa ttcatcttca tcaatgtctt ccatcaactg cttgtctatg cgttcaaaaa
     6961 aagccttaac ctgttgcatc tgagaacgtg ctttgtccgt cagacgaaca aacttagccc
     7021 gcttatcaac aggactcgcc tccaattcca ccaaaccatt ttgcactata cgcttaacca
     7081 gattactagc aacagacttg gtaatattga gttcctgctc gatatcttta atcaagacca
     7141 agtcttgatt tttctagcga ttatccaaaa aacgcacaac ctgaccttgc ggcccaccca
     7201 taaattcaat gccgcaacgt ttggcttcct tttgcaccat caggtaaatt tgatgaccaa
     7261 aacgcttaaa gactaacatc ggtttatcca taatctcccc cttctaaata aaaatagttc
     7321 tctggagaat aattaaattt ctatgagaac tattttcttg attaaaaaaa tcccaagtga
     7381 ttttctcact taggatcatg ttctataggt taaattaaaa cccatctacg ttcgtataaa
     7441 tcttttggac gtcttcgtcg tcttcaagaa cgctgtaaag tttttcaaag gtttcaaggt
     7501 cttcgcctga caattccact tctgactgag gaatcatttc caattcagtc acttggaatt
     7561 cttcaatacc agactcacgg agagcaacga tagccttgtg aaggtcagtt ggcgctgtgt
     7621 aaactgtgat tgtaccttct tgtgcttcta cgtcatccac atccacatcc gcttcgagca
     7681 attgctcaaa gactgcgtcc gcatcttcac ctccaaatac aataacacct ttgttgtcaa
     7741 aaaggtaaga aacagaacct gaagcgccca tgtttccgcc gtttttacca aaggctgcac
     7801 ggacattggc tgctgtacgg ttaacgttag aagtcaaagt atccacaatt agcatagagc
     7861 catttggccc aaaaccttcg taacgtcctt ctgtaaaggt ttcgtctgtg tttcctttgg
     7921 ctttatcaat cgctttatcg ataatgtgtt ttggcacttg ggcttgttta gcacggtcga
     7981 taacgaattt caaagctgag tttgattctg gatctggatc acctttttta gctgctacat
     8041 agatttctac accaaatttt gcatatactt tagagttagc tccatcttta gccgttttct
     8101 tggctacgat attggcccat ttacgtccca ttaggaatct ccttttttca cattttaatc
     8161 tttcttatta taacacaagt ttttttgatt ttcactagag gaaatggatt ttattagcaa
     8221 atcaagctag gatagcactt tacctgctaa gatggtcttg cctttctatc tttatcaaca
     8281 gacactcatc cacattcaaa aaacaaacta gaccattatc tgcaaataga aagtttcagc
     8341 caagtttgac aaagtcagct caaattactg tttgaagttt gtagatataa gcgacaaaaa
     8401 caatcatact gcaccttttg ttgacagtct actccagaca tatcatagtt caagtaaata
     8461 ctttgaaatt caacagttct tataggcgct attgtattct aagaaatcaa tagaagagtt
     8521 tctaagcaaa cctctaatac tcaataaaaa tcaaaaagca aactagaaag ctagccgcag
     8581 gttgctcaaa acactgtttt gaggttgcgg ataggactga cctggtttga agagattttc
     8641 gaagagtata atttacgtgt tcccaagatg gagaaattag actagtacac tggcacttct
     8701 aaaccattgc tagcaattga tttgttcata tttaatttca ttttttccat aaatgggtat
     8761 tagatataaa cagcaaaata tttccgatac gtgtcattct tgaatttcca atcatctaaa
     8821 acaagtaaag gataatcaat cccctgtata tcaaggaatt ggctaccctt tttacttttt
     8881 tacacattct gtttgataga ttcattttaa catcacgagc atactccaat ggaaatcgct
     8941 aggcaagaga taaactttca gatattcgca gagagctcat cgcctctttt tgtcgcaaac
     9001 attcttctct cctaatcatt ttctacctta tcctctacct gaggatagag agttgttccc
     9061 caaatagaaa tcgtccgctt acgcactagt ggcaaatcgg ttttttcata aaccgtacgc
     9121 caccattccc aggcaagccc ggtacactct ctaattttga cagagagatt acgaacattc
     9181 ccttttaaag gaatactagt ggtaaagtga gccgtcaaat cctgcccatt tctgtcccaa
     9241 gccttaggag tcaagacttc cttaccttga tgatcatagg ataattcatc ccaagtaata
     9301 taatattggg caacataggc accactatga tccagcagta aatctccgtt tctgtaagct
     9361 gtaaccttag tctcaacata gtctgtacta ttttgaaagg tcgcaactac attgtcacgt
     9421 aaaaaagaag ttgtatagga aatcggcaag cctggatgat ctgctgtaaa gcgactgcct
     9481 tcttgaatca agtcctctac catatccacc ttgcctgtta caactcgggc acccgaactt
     9541 gggtcgcccc ctaaaataac cgccttcact tctgtattgt ccaaaatctg cttccactct
     9601 gtctgaggag ctaccttgac tccttttatc aaagcttcaa aagcagcctc tacttcatca
     9661 ctcttactcg tggtttccaa cttgagatag acttggcgcc cataagcaac actcgaaata
     9721 tagaccaaag gacgctctgc agaaattcct ctctgtttta aatcctctac cgttacagta
     9781 tcttgaaaca catctcctgg atttttaaca gcatctacgc tgactgtata ataaatctgc
     9841 ttaaaattaa caatctgaat ctgcttttcg cctgaatgga cagagttaaa atcaatatca
     9901 agagaattcc ctgtcttttc aaagtcagaa ccaaacttga ccttgagttg ttccatgctg
     9961 tgagccgtga ttttttcata ctgcattcta gctgggacat tattgacctg accataatct
    10021 tgatgccact tagccaacaa atcgtttacc gctccgcgaa cacttgaatt gctggggtct
    10081 tccacttgga gaaagctatc gctacttgcc aaaccaggca aatcaatact ataagtcatc
    10141 ggagcacgat cgaccgcaag aagagtggga ttattctcta acaaggtctc atccactacg
    10201 agaagtgctc caggatagag gcgactgtcg ttggtagctg ttacagaaat atcacttgta
    10261 tttgtcgaca agctccgctt ctttctttcg ataacaacaa actcatcggg tagctgatta
    10321 ccctctttga tgaaacgatt ttcaatactt tctccctgat gggtcaagag tttcttttta
    10381 tcgtaattca tagctagtat aaagtcattt actgctttat ttgccatctt atacctccta
    10441 ataagttcct ggattgagtt gcataaactc agacttgttc agcgaaatca gccgtggttg
    10501 gactaagtga tccaaaattt cctcgtacaa ttcttctgag acattgcgtc gccgtctggc
    10561 tagataagaa gtcggaataa ccgtattatc caacataaat accttatcta agtcaatcaa
    10621 ggttggtctt gtaaaaggat tacgagctag atccggctct tctatcataa agttcttgac
    10681 caaacgtctg gtcaagagag ctggtttgaa ggtctgattt ttaaccaact ctttgttttt
    10741 agtcatgctg ttgtcaatac agatatacat atgattcttc acagccaaat cgctactaat
    10801 agtcggaaaa ggcaaataaa gagctacaac atctcctctc ttaatcaagc aagagcaccc
    10861 ccttttctcc taatgtaaca tagacaggat tgaccaagtc ttctgattga ctcagaattt
    10921 ccaaagtttg agtttggcgc gctgtcaatt tagtagcatc ttgtctcttc aatacaaaat
    10981 gcttgtcgcc aataaccttg acaatataat ccttctccaa agctgactgg taaatccaca
    11041 tcagatgttg tctgtcctga gaactcaaga gagaaggatt ttcaagcctc ccgatagtct
    11101 gataaaaatc aaaaacagga gctaactcct gccaatctga ttggctagtt gtcaaggcta
    11161 gaaaaagggc tttgcgagct gatacttctt ggttagcctt gagagttact ttcccctcca
    11221 agttttttag aaatcgggaa actccagaaa gcaaattttt ctctaactgc gagaaataaa
    11281 aacctttcgt tcccagacat aagtctttca tgtcgctttc tctagcaaat aagagctcaa
    11341 acatttgata gtaaaagaaa aatatctggc actgggtcgc gctcatcttt tccttatcgg
    11401 cttctttttt taaccagagc aagggcgaca ggtagctgga ttgagacatt tcctctacct
    11461 cctactcttt tttaactgga gcatctgcac tagctgccac ttcttttgac tggatacttt
    11521 cccactggtt aatctcctct gagataagac cttcgcatgt cttgacaaat agggcaaaag
    11581 ccttggtctt tcctgcatat ttctccgttt ggcattgata gaggaatttt tctttctcca
    11641 ggagttgcgc agttttttgg taagaaatcc aattttcctt tgcattatac aaattgataa
    11701 tcccctcaca cagcaagccg agactggata aggcaaccga aatcaaacgg tagcgatcac
    11761 ctggcatagg aatagcacaa aagacagcta tgaggaaacc tgccacgatt tctgttattt
    11821 ttaatacctt atagcgccta cgatgttgaa cgcttttctt taaaaaatga gctatctgta
    11881 cgtctaatcg ctctgtcagg tacatttctt ctggcgtcat attcgtaact cctttcattt
    11941 actttgataa ccatagtata acatatttga atatcaaagt atagtaaaaa ctggactata
    12001 acttattaga ctccctgcga aacaaaatat ggtatagtag ttctatgaat tatgaagcaa
    12061 gtaaacaatt aactgataca cgatttaagc gtcttgttgg tgttcagcgt accacttttg
    12121 aagagatgtt agctgtatta aaaacagctt atcaaaaaag tcggacaagc tggtaaaatc
    12181 ttggctgaca gtaattatca agggctcatg aagatatatc ctcaagcaca aactccacgt
    12241 aaatccagca aactcaagcc actaacagtt gaagataaag tctataacca tgcgctatct
    12301 aaggagagaa gcaaggttga gaacatcttt gccaaagtaa aaacgtttaa aatgttttca
    12361 acaacctgtc gaaatcatcg taaacgcttc ggattacgaa tgaatttgag tgctggtatt
    12421 atcaatcatg aactaggatt ctagttttgc aggaagtcta ttatatatat gcacagacat
    12481 atgaaatctt tttgatacag ccttcttttt acatagagag acagcagtta tgatatattt
    12541 atccattcac aacatcttct gtaccaatac tacaatattg gtacattttg attacacaat
    12601 cgtttcaaaa aatatgatgg aagcctgagt attttatagt aattcccttc ctatcaacta
    12661 gatcaaccag ttgagtgttg aatgttgaaa caccctagcc tcagcaaagg actatgatca
    12721 gcatttccta gccaatagga cgctccaaat cacctattct aagtccatca ctagcttggt
    12781 cagtaagata cagactgcaa ggcaagactg acgtggttga tgagattttg gaagagtatt
    12841 acaatcatag attcaccagt agacttgacc gcagatttaa ctatagtaga ttgaaactag
    12901 aatagtacac ttctgcttct aaaacattgt tagaaatcga tttgactgtc ctgatcaatt
    12961 tgtcctgttc tcgtttcatt ttactatact aaaaaaccac ctgaaacaaa tcaagtgact
    13021 agaggataaa aacaaagact gggcaaaaag ttttgaaaag caaaaaacgc ataatatcag
    13081 gtcttgaaaa accttgatac tatacgtttg attgtgggaa gattgacttc attttctcct
    13141 gaaattgaag ttttttctag tttccagata tagacgaatt caatatagcc atctcgctac
    13201 aattatttta accatcgaga aaatttttca gaatttcaaa aatttcattt tgatccaatg
    13261 aaatgtcatc attttgaaga atagttgact tcacaggctc taattctatc acaaagcggt
    13321 gcatgtctgc ttttaccgca ctacttgata ttatagccga taacttttca tctcctagca
    13381 aggaagctgt caaacgggta atgtcattca aatgcttttt aatggactta cttaaatctt
    13441 gagcacctgt agcagagcgc tctctcatat ccagccaagc tttagcctta aaaataatta
    13501 atactcaatg aaaatcaaag agcaaactag gaagctagct gcaggctgct caaaacactg
    13561 ttttgaggtt gtagatggaa gctgacgtgg tttgaagaga ttttcgaaga gtatagacca
    13621 caattactca ataccgaata cccctgaatg gtttcttttt catgcaccaa tatattataa
    13681 taatcttcat ccaataataa ggctgataaa ctagcatctt ggtcaaaatg taagggaatt
    13741 tctcgaccgt ccttctttaa tgaatattct ggtaagatac taaatagttc aatcatagaa
    13801 ggaaactcag gattagttgt tgtaaatcga aaaagctgcg ctttctcatc tttctgactt
    13861 ccttgatact ctcccaattc taaaaaatga ttcaaggtag tataaaattc cttatttttt
    13921 acttcatcaa tgatgaccat atcataatct tttgttgtgc gacttttaaa tccttgcgaa
    13981 tccaatacga tagaggtagc agttccccca atcagaacat aatagttctg aaaatccgca
    14041 aacgtttctt gaaaaataac tttcgtatta gctggcatca tcttctccca gatactgtaa
    14101 tatcatattt tctagtgctt cactctcttc ctctatacgt gggtcatcat catcttttaa
    14161 ggtcaaataa agagaaatcg gatctacaaa ttgtttatca tgattatttt taaaatcatt
    14221 ccaaaactca gatacaaaag gacgatattt ccatatctct agcatctttc cttttaaaat
    14281 atgctgagaa agtggcaagg gtaactgatt gaattttctc tgccatatga catagctaat
    14341 attttcatcc gtttcagcta aaaaagttga atgcgacaaa gcataagcac caccatatag
    14401 aaggttagaa acagatttta tctgctttat atcgccatct ggcaataaaa tccgtttttt
    14461 gatgggatta aataaacatg acacggattt taagaataat tctttctttg acaccgtata
    14521 tgtgtaaagc ttattttgct tgtttaacaa atataaagct ttaaaagtcc tcaaacacct
    14581 ataaattgtt gagtttggaa gtccagtgac ttgtgaaagc aaatcaacat ctactacttt
    14641 ttgacctttt gtcaataaaa aggcaatcca cgttaattgt tcgctaggta ttaattcctt
    14701 agggacttca gtatcattcg cattcagtac tagtcccaat gtagggaaga agaggtttcc
    14761 cttaaagtct acaaacggaa ctctagcttg aagtaattgc ttttttttca ccgtctgata
    14821 acttcgaaaa caccaaaaca acatccatat tggctttatc acccatagtg cgagcctgag
    14881 taacaaatga actcaaactc ccccttctct tttctttaat caataaaaat gattccttat
    14941 gaaaagtcat ttgagtatac tcaaactttt ttacaaaact gattggtaaa gtcagttcct
    15001 caatactgac atcaacataa aaggattgaa aaattgacat tatctttttg acattcatgt
    15061 tttttcctta ttctatcatt tttattatat tttatcattc ggtataataa aatataagtt
    15121 ttttgataaa ataaccaaaa actactcgct atcccctctc acattaccct acatatcgtt
    15181 tgacatgcga ctgatagttc aggaaaactt caaggagaac ttttctctca tccactatgc
    15241 aggacttact atttcacttc tactcctata ggctcaattt gacacttttc tttttcgaat
    15301 tgctcatatg cctcctgaat agtgagttcg atttatccaa atttattttt gtctattttg
    15361 atgaatactt ccacgaagat agtctgaaaa tgaatttgca ccaattttcc ttctcttttt
    15421 aagcatatta ttccagatat gattgccctc ttgttcagta ataaattacg ctttaaacgc
    15481 ttcaaccagt atatctcctg ttgtcatata ttctaaagaa aattctttta catatgattt
    15541 aacatctctt aggttattac ttcctaatat cccattatgc tttttcgcta aggaaataga
    15601 agccgcttct cccttaccaa taatcttgtt actatcatga tttcttgtta aatctctata
    15661 taatgcgtat tcttcagttc caatgtctat gctcacaatc tcagctgaac ccttagctac
    15721 caactgatct atcctagatt ttaaatgggg aattgtaggt atattgattt catcatacac
    15781 ctcttgtgga ataacaattt tacccaaata gagcttttct aaaagatgtt cagtgccaac
    15841 ccataaaaat actgaaatac aatctgcatc aataaataca cgactagtca aacgacaact
    15901 cccccctctt catctagccc atatacaata tcatatctga aagcatctag taacagttcc
    15961 tcatacttcc cttgcgaaat tctgttattt tctaaaagtt gttcagttag attaatatat
    16021 tatcctaata acatttcttt ttactttctg acaaaggacg atataaactt gtatcatagc
    16081 ctaatcttga agctgtctct ataacactaa tatccatatt tttaatttct tctgcatcaa
    16141 ggtatccatc attcctcaat ctatataaca tagctttatg actgatacca taaaactgac
    16201 ccaattttat aatatcttct acttcaagat gagttctatt ggcattttct ctgatttcct
    16261 caaccatcct atacagtgaa gatgggaaaa ttaaaaaata agaagcaaac tgatccgctt
    16321 ttctttcagt ttcatctcct tcaccaatca agataagact gactgaactc ttcttcacct
    16381 catcataata aagatgatac agttcatgtg ctaaagaaaa tctttacctt cctaatgaca
    16441 tgtctgaatt gactgcaatg agactgaact gagttccttt ataacagact ccgctaatat
    16501 tctttccgag tccataaaat accagcgtca aattttctat cttttgtacc aatttaaaaa
    16561 tatctatcgg cgattcacca tcagctccca acttttttct aagatttgga gctttattac
    16621 ttaaatccat tcgtgatatt cctttcacct ttttccattt tggcaatcat gctttgattc
    16681 aaagacaaat actcagcaat cttatcttga gtaagatttg aagatattct aagttctttt
    16741 attctttttc caacatcaca tacatttatc acatacattt atcatattca tacacctctc
    16801 ataaaaagaa tagcacactc ttgtcataat tttttaaata aaaaaattat gacaaaacaa
    16861 ggaagcaatt tattgatgct acttaaaaat ctaaaattga tgatattaaa cctatttgat
    16921 gagttcctat caaaaatcgt atcttcaacc tcaaaacagt acttaaagct atccgactcg
    16981 gtttacattg tcaaatttag attttatttg agcataactt tctagtttgc tttttgattt
    17041 ttgtttaata tagtagcaaa aattgaagga aatatctcca caagaaaacg catactatta
    17101 agctttttca agacctaata atatgcgctg ttctgatttg aaagacattc cattattatt
    17161 ttactgtaat caagccatct ggctctactg tgaattctgg cttgtctgcc agtgttccgt
    17221 ctggtttgag gtagtaccag cctgttccgt ccgctgactg gataaaggcg tttgatacca
    17281 tggcgccttc tttagcgtct aagtagtacc aagtgtcctt gtacttgacc cagcctgtct
    17341 tcatggcacc ttcttcgttg aaatagtacc acttatcagc gattttcttc cagcctgtag
    17401 ccatttcacc tgagttgtcg aaccagtacc agttgccgtc tgtgtgcttc ctccagcggt
    17461 ctgcaagcat atagcctgaa ctgtcaaagt agtaccaagt gccattgatt ttctcaaact
    17521 tgtcttttgg ataagagccg tctgaatgta cgtaccagta gccagtgtca ttcttctgcc
    17581 agcctgtttc aatcgtcaag ccgttctcaa tatcatactt aaactgctca cggctaatgc
    17641 cccattttgc caagtaaggg tatggatcca catggtctga gtggttgttt ggttggttat
    17701 tcgtgcaata ctcgtgcgtt ttaattccag ctaaactccc tgtatcaagc gttttcggca
    17761 aacctgcttc atctgctaga ttgcgtaaga gttcgatata aagacggtag tccgtcatga
    17821 actcttcttt agttgaatgg ctttcaatca gttcaaccgc tgcataggtc tcagcattcc
    17881 aaccgccccc aacgtcccag gcaccattat caacaggtcc tacctgcatg atgcaaccgt
    17941 tcccaacaat gtgcgagaaa aaacctaatt ctgggtcttt ccgccagtga taatccgctt
    18001 cattctgtac ggttgaatgc ggattcccag ttgagtgtgc gtgtacttgc ctatatggtt
    18061 gcacgccgac ttgaggcaaa tctgttctta atttactcac attaatttcc atattctact
    18121 ccttatcaat taaaacaact cattttttac aatccagaac cagaaactcc tttatttcta
    18181 ccttacaaag aagacaatct tagtcacgat taggcttgta gatagaacct caaaacgcac
    18241 tattttgaca ctgtaaatag gactgacaag gtctgcattc tatctacaat aacaccccag
    18301 actaaaaagc ttttcaaaag tatattttta cagtctctat atgtcctttt cataaatact
    18361 atactttatt atatcatata aaagaagtca aaagtctgtt aaactatttt caacaccaaa
    18421 ctgaagaaga gaacacaagt tttttcgatg ttcactagag gaaatggatt ttattcagta
    18481 aatccaacta ggattgcact ttggttgcca aaattgcctt tccttctttt atcaagggat
    18541 gacggaatag tgagaagtac agttgaactg tcatggcaac ccagataaga ggttcacaaa
    18601 ggataacacc cttatatcct gcccaaggaa taatcaaaac cacaaaaacg atttttccga
    18661 ttagttcaat aaagctagaa actagaggaa ggatcttctg ccccaagccc tgcaagcaat
    18721 tgcgataaat caacaagagg ctcaaaatgg gataaaaggc tgaactgatt tgcagataga
    18781 gacttccatt ttctatcaag taaccatctg tcgaactagc caagaaggaa accaaggctg
    18841 gactggcaaa aaagaggaaa atacaaacaa aaactgccca ggatatactt aaacgactgc
    18901 cgattcgaag accttgaaca atgcggtcag gtcgcttagc tcctagattc tgagaagcaa
    18961 aggtcgtcat tgatgcagaa atagcggtca taggaagaag ggcaaaggtc ataatgcgtc
    19021 gagctgccgt ctgggcacta ataatcactg caccaaatgt attaacagaa aactgtaaaa
    19081 tcacactgcc gatagataca attgaactca tcaagcccat agccaaacct tgctccaaga
    19141 gatccgcgta caagcttttg tcccatttga aatgtttaaa ctgtggcaag agttctggca
    19201 cacttttacg aatataataa aagcagagaa ccgctgataa accttgcgaa ataatggtag
    19261 caagtcctgc ggattgaact cccagatgca attgcgtaat aaaatagaga tccagaacca
    19321 cattaaccaa ggcagagaaa atcagaaatc ccagggctgc tagactgtca ccaatatacc
    19381 gcaacaagcc tgcaaaaaga ttataagcaa agctgacacc tacacaggtc acaatcatag
    19441 aaatatattg ataagattga ggaagaattt ctgcaggagt atctaagtat tgcaagagag
    19501 gatacaagcc aagaaagccc agcaacataa ctagaatgct caaaagagca cctaaaatcc
    19561 aggtggctgc tactgcttcc ttgattttag tgaaattccg agccccataa taacgagcaa
    19621 tgacaatccc catgccattg ccaacaccaa gtgtaaaacc tacaatcaga tcaaaaatcg
    19681 ctgtcgtcgc tcctactgca gccaaggatt cttgaccaag aaatcgtcca acaatcaaga
    19741 catcagcagt gttatagagc tgttgaaaaa tatttgataa caagattgga aaggtgaagc
    19801 ttaagagcga gggaagaatc ggaccatgta tcaggtccac tgttcgtttt ttattcataa
    19861 agctattata tcagctttcc agaggagcga caagaaacag caaacttata tatagcggaa
    19921 tgaaataagg acagtcaaat cgatttttaa caatgtttta gaagtagatg tgtactattc
    19981 tagtttcgat ctattatagt tggttgagtt tggaatagta cgctgtagct gctaaaacat
    20041 ttctagaaat taatttgact ttcctaataa agttgttcat atcttatttc aatctactat
    20101 atataatcta aaaacttgaa tcaaaaatcg aaaaagtagc ggatttctcc actgctttaa
    20161 cagcttattc ttcaatttcg atttcaagtt catcgcctaa gtcaagcgga acttcttcat
    20221 tcactgcttc ttctttcttt ggctcatctt ttttgttttc agtatcttgt tctgaaactt
    20281 cttctccatc aatcaagcca aatttagaac ggacttgctt atcaatttca tcaaagattt
    20341 ctgggtgctc tgccaagtat ttcttagcat tctcagaacc ttgcccaatt ttttcatctt
    20401 tgtaagaata ccaagcccct gcttttttga taatatccaa atcgcttgca atcttcaaaa
    20461 gctcaccagt cttagaaatt ccttctccgt acataatttc aactacggct tccttaaacg
    20521 gtggagctac cttatttttt acaaccttaa tcttagtttc tttaccgaca ttggtttctt
    20581 tttggtcacc agttccctta atttgtgtat taccacgaac atccaagcgg actgaagcat
    20641 agaatttcaa agcacgtccg cccggtgttg tttctggatt tccaaacatc actccaactt
    20701 tttcacgcaa ttggttgata aaaatggcaa ttgttttggt tttattgata gaggcgccaa
    20761 gtttacgcat ggcctggctc atcatacgag cctgcaaacc aacatggcta tctccgatat
    20821 ctccatcaat ttccgcacga ggaacaaggg cagcaactga gtcgactacg acaagatcaa
    20881 ctgcacctga gtcaatcaat tttcccgcaa tctcaagacc ttgctctcct gagtctggtt
    20941 gagacaagag caattcgtca atattgacac caagggccgc agcataagct ggatcaaggg
    21001 catgttccgc atcgataaag gcagcaatcc caccttcttt ttgcgcttgt gcaactgcat
    21061 gaagggcaac cgttgtctta ccagatgact ctgggccata gatttcgatg atacgtccct
    21121 taggataacc acctgagcca agggcaatgt caagagctaa agaacctgag ctcatcactt
    21181 gcaccttttg ctccgcacgt tcacccaaac gcatgattga tcctttacca aagtctttct
    21241 caatcaattt aagagcgtca ttcaaggcct tttcacgttc tgccccaaat ttttttgaaa
    21301 tttcttctaa tttttttggt tttttcgcca ttctattctc ctacattcta atgatcctca
    21361 gacctatcta ctattatatc aaaagttagt cacttaataa agccttgcga actaggttaa
    21421 aggcatgcat aaccgcaata tgacgtacat ctgctcggct tctgcctcca atattaacct
    21481 tgataacctc agttccttgc tcttgcgcca agcctatgaa gactgtccca actgggtgtc
    21541 cttctaggct atctggtcct gccactccgg tcaaactaat tccaaaatca gactgggtct
    21601 tgcttcgtgc ctgctcagcc atcttctgag ctgtaaattc agacaccaca ccatgttctt
    21661 ccaaattctt ggcaggaata tccaacatcc ttgatttttc ctccaagcta taggtcacaa
    21721 aaccaccctt aaatatactt gaaactccag aaaaattcgc cacggtagct tggaaaagac
    21781 ctgccgtcaa actctctgca gccgcgatgg ttttcccttg ccttttcagt tcttctacca
    21841 caatgctggc taaactagtt tcttccccat aaccatagca aaagtctcgt aaagaaattc
    21901 cttcgaaagt ctggcagtcc aagatttgat tttccaagat atccagcgct tgattcgcct
    21961 cttcttgact gctagccttt gttgacagac gtagagtgac ttctcctgtc ttggcataag
    22021 gggccaaggt aggatcgatc tgattatcaa ttaaatcagc caaaatcgta accaactggc
    22081 tctcgccaat cccaaagaaa cgaagaactc gggaatacag cttgctccct gtcatcaact
    22141 tgggtagaag ttggtttaag accatgggtt tcaattcact tggcggacct ggaaggacga
    22201 cataggtcac tccgtctact tctaattttc ctccaacagc cagtcctgtt tcgtttggca
    22261 gtggaatcgc tccttctaca atttgagctt gtctttcgtt attcggtgtt cgggcatagt
    22321 ctggtcgcag ggcaaaaaag atatccaact tctcctgagc ctgaggatca aagactaatg
    22381 ctttccctaa aaatttagct agggtttgtt tggttaggtc gtcctcagtt ggccccaaac
    22441 cgcctgtcaa aatcaccaga ctgctacgtt gactggcaat ctcaagcaaa gacaagagac
    22501 gaacttcatt gtctcctaca gccgtctgaa aatatacatc taccccaatc tcagctagtt
    22561 tttccgacaa aaactgggca ttggtgttga caatctgtcc tgtcaaaatc tctgttccaa
    22621 cagcaatgat ttctgctttc atgtttcctc ctacctatct attcgtattt ttttgaaaaa
    22681 atcgcaggaa ttttcctacg attgattttt ttatttgtat caaaagttaa ttatcttcat
    22741 caccaacagg tgctctgcca aataaatctt caaataaaac cgcattggtt tcaagctgag
    22801 taacttcttc ttgtcccaaa gaacgtcgga gtatattttg catttccaac atatgtgctc
    22861 tcgaaacaat ctggtaagaa acaccttgaa gtatctctcc ttcaccctgc aactgctgag
    22921 tttcaatggt tttaaatgaa tctttatagc ctagcaagtt agggatactt tttgcagaca
    22981 aatcaatatt ggtctgcata ttgtcactca aagcttttag aatctcttga taatgaccaa
    23041 cgctatttaa actgagagct ttttccatga ctttttgaat aacttcacgt tgacgttttt
    23101 gacgaccata atccccctca ggatcttggt aacgcattcg tgcatagact agggcttctt
    23161 ctcccccaat atgttgctcc ccaacaccga tagaaatagt attaaattct tcttggtcac
    23221 tgatagaaat tgggaaacct aggatattat tgactgtaat acctcctact gcatccacta
    23281 gtttttgcaa ccctctcata ttgaccatta catagcgatc aatatggata ttcatcattt
    23341 tttgaatggt ttctatagca agctctgctc caccatctgc atatgctgag ttcagtttcg
    23401 cttcatgagc ctgaccattc cctgattcaa tgcgcgtcag aatatcccgc tctaaactca
    23461 tcattgttgt ttttttcgtt ttaggattca ctgtcatcaa gatcatgcta tcacttctac
    23521 cgacccaagt ttcagttcgt tcagcatttc cggtgtccac tcccattaac agaatggtta
    23581 gaggttcagt cgcttcaata accttggttt cttcgccgat ttttttatag gttttagcta
    23641 aggtttctgt cccttgttga taaatagtat aagcaaaaac acctactcct actacagtta
    23701 cagaaagtaa agctagcacc attccaataa tttttttaac catatttcta ctaacctatc
    23761 agtttaccca tcaagtaaac atcgataaat ttcccttctt ctatatatgc cccacgctct
    23821 tggctacctt caatgacaaa gccatgcttt tgataaagat ggactgctgc ttgattacga
    23881 gtttggacag tcagttggag acgacgcaga atgccacctg cttgtgccca ctctatcgct
    23941 tcttctagca acaaacttcc caagccatta ttccaatatc tttttccaat cacaatgaag
    24001 agatctccaa tatgacggac tctcttacgc tgatcagctg taatatttac aataccagca
    24061 attttgccat ttaagaatgc aagtaaggtt atctgattgt ccgaactagc ttgcttgttg
    24121 aggaatattt ccatctcctc actagtcaag agaataccat ctccgtctag gctggtaaag
    24181 tctgtctcca aactcacacg atttaaaaag gccactaatt cagctgcatc tttgggctct
    24241 gcttccctaa tgagcaattc atactccata ttgaagctcc tctaacaatt tctcagcacg
    24301 caaacccttt gcctgaaaat ttaaacggcg tccatctgct tcttttagaa tttccaattc
    24361 taaataagca tctggcaagg catctcctaa gagatttccc cactcaataa cagtcacgcc
    24421 gccaccaaag ataaactcat ccaagtcgat agaatcagca tctccttcaa tacgataaac
    24481 atctaggtga taaagtggaa gtcgaccttc atactctctc acgatagtat aggtgggact
    24541 tttaatcatt tgagaaatct gtaatccttt tgcaagtcct ttagtaaagg tcgttttacc
    24601 tgcacccagt tctccagtta agattaaaac atcattcttt gctaatagat ggcccaaacg
    24661 ctcccctaag gcttgcaact cttcttcatt ttttgtgtac atactcttat tataccaaaa
    24721 acttttcttt tgtgtctatt ttcctactaa acttatcatc ataacatcca taaaaaacag
    24781 gctttctcta aaagaaaatg agcgtaacaa tgaccaatac aagatctcgg aaaatatgac
    24841 cataaaagga aacttccttc ttaaccgaat ttgggacaag ataggctgca aaaaacaagc
    24901 ccagtccaat ataaatcaga agtgagacaa tggtcattgg atttcttaag aaaagaagtg
    24961 ttgctaaaat agtcaccaac actgtctttt ttctgtctag catagcaaga aaatcgcgca
    25021 cgtatttttt caagggtaaa aaaatcagca aatctagccc aaataggaaa aagaaggatg
    25081 gcaataaaaa gtcaactaat tcttgctgca gcgtattttt gatgaacaag ttatctgaca
    25141 aaacaagaac agctcctaac aaattaatta agagtaacat actgtaaaaa agcttcaccg
    25201 acttcttact ggctaggaca ctatggactt cttgcttacg ggtataaaga taatttactc
    25261 cagcacagat tcctgaaacg aaaaccatgc ttccgatgaa aaaagctgta ctttgtttaa
    25321 aggacaagat gcattccttc cataggaaac agctactcaa actgatttga attaaagcta
    25381 acaaaaataa gattctcatt gatttcatct tctctctccc ttcctaccaa tcattatact
    25441 aggagaaaag agagaactgt ttctaatctt ctcaaatgtc tctttaagac gctaaacaaa
    25501 cactagagac taatactcaa tgaaaatcaa agatcaaact aggtagctag ccacaggttg
    25561 ctcaaaacac tgttttgaga ttgcagatag agctgacgtg atttgaagag attttcgaag
    25621 aatataaatt tgaaatcatg aaaatccgtc tagcgggtgt tttttttgtc tcgcacctaa
    25681 cggagcgaga cgaactaata gtcacataat cataaggctg atagtattca tttcactatc
    25741 agccttacag gttatttaac gtttcagaaa aactataatg tcaagattaa ctaaacagta
    25801 tctaattcct tcaaataatt ttctatcttc atcagcatta aaggattgtt ataaatctta
    25861 cataactctt ttgcttctat ataataattt ttgacttgtt ctctgtctag aaatttggct
    25921 ccagcatttc ctacaagaat aagtagagga gccagttggt agcttgtctg tctttgttta
    25981 cagagttcaa tcgtctcaag agcttcttgg atggcttcat tatatttttc ctttgatact
    26041 aggtagtgag cgtagttgta acgaactctg atgtagccaa ataaaaactc ttgatggtcc
    26101 aaattttttg tctgatacaa ctctattaaa tgagagtagt ttgcctcata ttcttgttca
    26161 cgacccacta aggaatagaa attagataga gtattcaacg cctttaaata aatcagagta
    26221 tttgaggaga cttttaataa tatattttcc aatgaagaaa ttgcttcaca cttactgtca
    26281 tattgataaa agtcaataat agctttaatc cattcaagat aagttcggtc ttctagtgtt
    26341 agaaaagtac ttcgttcaat ctctattcta taaatatatt ccaaatcgtc ataatttcta
    26401 tcgtctaata gtcgagcaga caattgcttg aaattagaga ggttagattt aatttcaatt
    26461 tgttcattaa aaaaataatc taatggtact tcaagtcgtt gagagagttt gaacaaaagg
    26521 tctgcggagg gaatgaaatg ccctctctca attttactaa tctgactttg ttcacaaatt
    26581 ccttctgcaa gagtttgttg ggagagtctc aactcttttc ttttcaatct gaatttctct
    26641 gcgagtgtat tcattaaaga taataaacct tcctatttgc ttaatttcat tataaagttt
    26701 ttagttcaaa atagcaagtt aaaggaataa ataattcttt atggtaataa acaaaaaaaa
    26761 aaagttaaaa attacataaa aatacttgac taaataaaat atatctgtta gaataaaaac
    26821 aaggaaaaag aaaggggttt cattgcatga gaaaaaaacg tggaattaaa aaattagtta
    26881 catttgcatt gctaggtgtt tttatgttta gtaatacaat tccttaccaa cagtttattc
    26941 agaagaataa acaattggag attcgagtgc aatcgcaaaa gaagtccaat ggtcttgatg
    27001 ttgggaaggc ggattaaaac ccgatatttt gcacgagaat gagagaatta taatttatct
    27061 gaaaaaacga aaaatataga gcaacttatt taacttttta taaggaggag ttattactta
    27121 tgaccaactt taattcaaac gaaaaatttt gtggaaaaag tttaaaatca ttgtctgctg
    27181 atgaaatgag tttaatttat ggtgcatctg atggtgcaga gccacgttgg acgcctactc
    27241 ctattatttt gaaatcagct gcagctagct cgaaaatatg cattagtgca gctgtttctg
    27301 gtattggggg gctagttagc tacaataatg attgtttggg gtaaattaaa atgaaaaatg
    27361 attttgtaat cggaaagagt ttgaaagaat tatctcttga agaaatgcaa ttggtttatg
    27421 gtggcacaga tggtgctgac cctagatcaa caattatatg ttctgctaca ttaagtttta
    27481 ttgcatcata tttggggtca gctcagactc gttgtggcaa agacaacaag aaaaaataaa
    27541 atattcaatt ttaaaaataa aagttgctct ttattttcct ctctcgtaac taataatttt
    27601 gagagaggtt ttttttttaa aacaatagta agtcgtatag gtttgaggta agtaaatgaa
    27661 atataaaatt aaaaatgtgc ataaaacatt gtttattaag gaaagatatc aaatattatc
    27721 tgaacgaaat gataattcct taaataactt ttcattaaat aattggcgtt ctacaatgtc
    27781 aattatttct gaaaaaactt ttgaagaaat gttgaaatta aataattaca ataaaaaaat
    27841 attttctaac actgtgaact atgattatac cgaggaacag ataagactat attcagaata
    27901 tgccaaaaat tcggaatggt ataaatttgc ggagggttca tttgaaatat ttagaaaaca
    27961 tccccaaaga attaatttta agaaagattt ttctagaatt ttggaaccct ttattattaa
    28021 tttgcttaaa ttaatcaata attatctaga gaataaagaa tacgagtgga ttgacaagaa
    28081 tggaaatatt ttttcctctc tagtatttta tttagaagat ttaatctatc cttggattgt
    28141 taaacctttg gttttagaga taaattcatt gcgtgaaaaa ggtttacttg aaggggaatc
    28201 ggagcagcaa cggtacaaat attttataac attgtttgac aaggaagaga atatattaaa
    28261 tttttataac aaatatcccg ttttactgag gcaaatatcg gagtcttgtc ttcggttcta
    28321 tacttatttt atagaaattt tatcaaattt agaaaatgat tttagtgtgc tagaagaaga
    28381 attagggcta agggggaaat taaatgatat aaaatttgga aagggtgata cacacagcca
    28441 aggaaaaact gttttgatac tcttctttga tgacgcgaaa attgtttaca agcctaaaaa
    28501 tttaataatc aataactcac taaatactat tgctgagtat atccgaaagg ttgatgaaaa
    28561 aattaggata agaatacctc gaactattgc ttattcggat cacagctatg aagaatttat
    28621 tgattatcta cctctagagc aaaagaaaaa attacctgaa tattattata attttggtgt
    28681 gcttttagca tttatatatt tatttaatgg gagtgatata cattttgaaa atttaatttc
    28741 ctatggagat atgcctgtaa taatagactt tgaaacaatg ttacagcaac ctctatttga
    28801 tgataaaact ggtcagagtt tgctggatac cctgtttcac agggtgactc gaactttgct
    28861 tcttccaaca gagggagtaa aaagggagga tggtcttgat gttgagatga gtgctcttac
    28921 aggaaatttt aagaaggatg cttttaatgg tcaagtttta attaatttaa atactgataa
    28981 ggtaaagttt gatattggga aaattgattt tgaaggtggg aaaaacctgc ctgttcggga
    29041 tggtgatata gaatttgata agtatataaa agatttcaaa aaaggtttta gggattttta
    29101 tctgatattt gaagagttaa ataaaacaga agaatttaaa atgctattaa aagcaaactt
    29161 gtatggttta aagacaaggg tactttttag agacacaaat agctatgctt cagtactatc
    29221 ttttttatat catcctgatt tttatgaaga aatgttagat agagaaaaag cattggaaaa
    29281 tctctggagc aataagtttt ctaatcaagg tattgtagca agcgaatgtg aacaaatgag
    29341 gttattagat attccgattt tttatacaga tacaaatatc aatgaaatct acgatgattt
    29401 tggaaatcat tttatttccc tacatcaatt ttctggatat gactatttta tgaaatattt
    29461 acctaataat aatttggaaa atttagaaaa gcaacttgat atcattgaaa tttattttcc
    29521 aagctttgat cagcgaaaaa aaggatataa attaaactta tctaatagaa aaaaactccc
    29581 aaatgaaagt ttagttacta ttctgcataa tgaagtagaa aatattgcag actctttggt
    29641 tattaataat atttatgacg aatatccaat ttggagtata cctgttaatt ttaaaggttc
    29701 taaatggtgt cttgaacaaa cgggtaatga tatgtatagg ggtagagctg gaatattact
    29761 gtttatgtac tatgtaaaat tattgaaaga taaatcatca tatactcaac tgtacaataa
    29821 aatgttatct gcaattccgc catctgtttc tttatctaag accacatttg gtttaactgg
    29881 ggatatagga tatttcattg ttctatccat tatagaggat tacgatacaa atactctcgc
    29941 atgcttaaat tatataaaga gtgttttaac tgagcttgaa aagactgatt ttgcaagtgt
    30001 ttcaaacaag tctgactata ttaatggtct tctaccttta attaatacac tggtaagata
    30061 ttataggaga ggaatagaga aggaacgtgt tctaaggcta gtattaagtt taggtgatac
    30121 gctatataat gatgtaagcg agagagataa tagtaatttt ggatatagtt ttggccatgg
    30181 actatcaggt gtaattttta cattaaaaaa tatttataaa gtgacaagac ttaaaaaata
    30241 taaagaatta attttacaac tagttcctag ggagaaaatc aaaattcatt ctttgaagtg
    30301 gtgtagtgga gaatttggga cattagttaa tcatccccaa agtgttccag agggaattgt
    30361 agctagttta gataatgata cattttgcca tggaagtatg gccataataa atttttacat
    30421 cgactacatg aaagaaatgg atactagtat ggaattggag tctttattgt gtagtgttgt
    30481 aatgaataaa tcaaaagaag gagagtatcg tatcgtccaa acaagcaatt tcccagattt
    30541 ttctttgtat acaggtgtga ctggtattgc ttatactttt ttaaggtata tcgcactgaa
    30601 tcagaatgac aaaaagatag ttatcccctc attacttgaa atctagctta atttatagtt
    30661 ttgtttctaa aatagaggtg tccactcatt aagcaatata aaaataccaa gattgactag
    30721 tttaatatgt aattctataa aatattttta atagtgtagc ttttcgttga gataataata
    30781 taataaagaa aggttctatt ctaattgcta aacggcttga ggtatatgct actgttatag
    30841 aaatgatttt aaactaaaat caaaattact ccaaaaatag tattgatttt ggtttaatac
    30901 aaaacatatg taataatgtg agtcaacaaa agtctgtttt tgtaccatac tatcttgaaa
    30961 aatctactaa attcaaattg agaggatgaa ttaaaatgaa taaaatattt atatatgcag
    31021 gagtgcgaaa tcataactct aagactttag agtatactaa gagactttca agtatcattt
    31081 ctagtagaaa taatgttgat atatctttca ggacaccttt caattcagag ctagaaatat
    31141 ctaattctga ttcagaagag ttgtttaaga aaggaattga taggcaaagt aatgctgatg
    31201 atggaggtgt tataaaaaaa gagttattag agtctgatat tataattatc tcttctcctg
    31261 tatatttaca aaacgtatct gtggacacaa aaaactttat tgaaaggatt ggggggtgga
    31321 gccatctttt tcgattagct ggaaagtttg ttgtaacatt agatgttgct gagagtaacg
    31381 gctctgataa tgtgtcagaa tatcttagag atatattttc atatatggga ggacagatat
    31441 tacaccaagt ttcaattacc aattcactca aagatattgc agaggctcag ttgatggagg
    31501 caacttataa aattgaagat gtacttgaag ggaaaattaa gtacaaaaca acggattatc
    31561 aagaaagagc ttaccagaca ttaaaattaa ttttagaaaa ttatgattcc gaacattttg
    31621 agaagatgta ttgggagaaa aaacgccttt ttgaagctaa tagtttagag gaatggtatt
    31681 atgttgaaaa tattaaataa ctctgtcata tatttatgtt tgattccgtt attgttccta
    31741 ttattgataa tttttccaaa tgattcatta atctattatt ttcgattgat tttaatttcg
    31801 ttaatatcaa ttacattaca tgaactaggt cattttttag tgggaagatg tttatcttat
    31861 aaactagaga tgcttgctac tccctttttc ttctatttca gaaaaaaaat atatttcaaa
    31921 tttccagtgt tattagcatt cggttattgt caaatgagta atagaaacat tactaatgaa
    31981 aaaaatagtg ataggaattt ggtgttctac ttctttgggg gaggtggagc taacctaatt
    32041 gtcgcaatat tagcactttt gggatttgtg ccgtacgcat cagaattttt tattttgaat
    32101 ataattcttt ttctagttac ggtatgttta ccaattgatg gaacagatgg caatgctatt
    32161 agagagatag ttttgtattc aaaagattca aaaacatatc agagattctt tgcgaacagt
    32221 ctctataata atccttatat aacaatcgac gattttgcaa aattaacctc taaagaaaaa
    32281 tctttttttt caaaatttga aaaatgtttg ataaaccttt actttgaagt gaaaggtgaa
    32341 gggtcagcat ttacaattgc taatcatgaa gtttttgatt caaatattca ggaaaatatt
    32401 atccatgagt actataaatt actacataaa tcttctgatt ggattattcc acagaactta
    32461 tctttagaag aagttgtttt taccttgtca aactatattt actcgaaaaa taataaatat
    32521 ttagaaaaga ttaagtatct aaagaaatta gtagatttta gacaagaaga aattatcgac
    32581 tttattttga acaaggagga agtattgtga aaattccaat gatatatcaa atggaaaatt
    32641 cagaatgtgg attagcatgc tgtgccatga tattgaacta ttttaaatat gagatttctt
    32701 taaatgaact acgtgaaatc tacccatcat ccagatctgg atattctctc ctatctataa
    32761 gtaaagtttt aggagatttt aatataagtt ctcatgcttt taaagcttcg gtaagagatt
    32821 taaaaccgct cagtttccca ctcatttgct tctgggagag ttctcatttt attattcttg
    32881 aaaaaattag taaaaacaag ttttatattt tagatcctgc aaaaggcagg cagagaatgt
    32941 caataagtga atttgaaagg cattattcaa atatcatttt aacatttaaa aagttagata
    33001 gctttatgtc tcgtaaagat aataagaagt cgcctgtttt aaagtatttt tttaagtata
    33061 ggaataagct agggatttta ttttttgtaa cagcattatt gtatgtaata caatcattag
    33121 tacctatagc taatagatac ataattgaca cgaatttcaa ggacgattcg tattcgtcta
    33181 gaatgttatt tactatatta tttatattta ctgtttcatt ctcactaatg tatttattaa
    33241 gacagatata tgttgcatcc ttaaaatata taatggataa agagattagc tatgatttta
    33301 tgaaacattt gatatattta ccttacagtt tttatgaaaa acgtacttta ggggatatac
    33361 tttttagagc taactctatt gtttatataa gagaaatact atcaaataat tttatagcag
    33421 ctatacttga tttgttaatg attgtggttt atgctgtggt tttatttagc ttttctaagt
    33481 acatggtaat ctttttaata tcactaagtc tagctctatc tattgtaatg tatccaatca
    33541 taaaaatctc aaaaaattta attgataaaa atataaaaga aaaggttaat gttcaaaata
    33601 ttacttccga agtaatttct aaaaatagtg atattaagct aactggagaa gaggaatttt
    33661 ggattaacaa atgggataat tttaatacaa aacagctcat cataggtcga aaacttgata
    33721 tacatttatc aattgttagt agtataacga atgttttaca aattattctc cctgttttga
    33781 cccttattgt aggtgtaaat ataaaaacat tcgaacaatt gacgttagga caaattgtag
    33841 caataagtac agtctcacca tactttattt ctcctataat ttctttaagt gataactata
    33901 tacaattaat gttattaaag ggatattttt taagaataga ggatgtgttt aatactaaat
    33961 ccgaattaat tccagaaaga gtcagtcaag atataaaatt tgataaaaaa atagaattaa
    34021 aagatatttg gtataaatat ggattatttg atgattatgt tttgaaagga ataaatgtta
    34081 ctattaaaaa aggagaaact gttgctattg ttggagaatc aggttcaggt aagagtacat
    34141 tagctaaaat tttattaggt ttattagaac ctaatattgg ttcaatagaa gttgatggag
    34201 tagaaaaaga agaaattggt caaacattgt atagaaagat ttttggagca gtgttacaaa
    34261 attcaaccct aagttatggt accttaagag agaatttgac atttggacac tttgtttcag
    34321 atgaagaatt aatgacaaat ctaaattcaa ttggtcttag caatgtagtt aaatctttac
    34381 ctcttggatt agagacaatc atcgctgaag aaggtaataa cttttctgga gggcagcagc
    34441 aaatgatact tttagctcgt tgtcttttgt cgaaaccttc ggtagttgtt ttggacgaag
    34501 caacaagtag tttagataat ttatctcaac aaattacaac ttcttactta agtgaaatcg
    34561 gtaccactaa gattttaatt gcccatcgac tagatactat caagtctgca gataagatct
    34621 tagtaatgca taatggtgaa attgtagaga ttgggaccca tagagaactt cttgaactag
    34681 gaggcattta taagcaattg tattcaaata attagttttt gattaaaagg gtaaatttat
    34741 gaagattatg aaaaaaaaat attggacttt agcgatatta ttcttttgtt tgttcaataa
    34801 ttctgttact gctcaagaaa tacctaaaaa tcttgatggc aatataactc acactcagac
    34861 tagcgaaagt ttttctgaat ctgatgaaaa acaggttgac tattctaata aaaatcaaga
    34921 agaagtagac caaaataaat ttcgtattca aatcgataag acagaattat ttgtaacaac
    34981 agataaacat ttagaaaaaa actgttgtaa attggaactt gaaccacaaa taaataacga
    35041 tattgttaac tctgaaagta ataatttact aggcgaagat aatttagata ataaaattaa
    35101 ggaaaatgtt tctcatctag ataatagagg aggaaatata gagcatgaca aagataactt
    35161 agaatcgtcg attgtaagaa aatatgaatg ggatatagat aaagttactg gtggaggcga
    35221 aagttataaa ttatattcta aaagtaattc taaagtttca attgctattt tagattcagg
    35281 agtcgattta caaaatactg gattactgaa aaatctttca aatcactcaa aaaactatgt
    35341 ccccaataaa ggatatttag gaaaagagga gggagaggaa ggaataatat cagatattca
    35401 agatagatta ggtcatggta cggctgttgt agctcaaatt gtaggggata acaatattaa
    35461 tggagtaaat cctcacgtta atattaacgt ctatagaata tttggtaagt cgtcagctag
    35521 tccagattgg attgtaaaag caatttttga tgctgtagat gatggcaatg atattatcaa
    35581 tcttagtact ggacaatatt taatgattga tggagaatat gaggacggaa caaatgattt
    35641 tgaaacattt ttgaagtata aaaaggctat tgattacgcg aatcaaaaag gagtaattat
    35701 agtagctgca ttagggaatg actccctaaa tgtatcaaat cagtcagatt tattgaaact
    35761 tattagttca cgcaaaaaag taagaaaacc aggattagta gttgatgttc caagttattt
    35821 ctcatctaca atttcggtcg gaggcataga tcgcttaggt aatttatcag attttagcaa
    35881 taaaggggat tctgatgcaa tatatgcgcc tgcaggctca acattatctc tttcagaatt
    35941 aggacttaat aactttatta atgcagaaaa atataaagaa gattggattt tttcggcaac
    36001 actaggagga tatacgtatc tttatggaaa ctcatttgct gctcctaaag tttctggtgc
    36061 gattgcaatg attattgata aatacaaatt aaaagatcag ccctataatt atatgtttgt
    36121 aaaaaaaatt ctggaagaaa cattaccagt aaaaaatggt ataaaagtgt taaatatacc
    36181 aaacgtattg agatatgatt tgaatatgtt acaattagaa tataaaaatg aacaaagttg
    36241 ggatagtttc atagataatg ttaatttaat tgagttggaa gagagaattc aaactactat
    36301 tggaattaaa caaataaaca cacacaatat tattactatt gcccgagaag ggtactctca
    36361 aaattattta cctaacactt cagaaaatac atataattca ttacaagtca gtttagttgg
    36421 agtattacta ctttttataa gtatggtaaa tattttatgg gctaaaaaaa gtaaatgaaa
    36481 ataaaatttg gagccctctg aaaaagtaag tcctacagtt caactaaaat gagtcaaaag
    36541 atgaatcacc ttgatgtagg ggagtttgtc ttattgctgc ctgaacacct ccgttcagag
    36601 gaagaacatt ataaatctgt ttttgaagac gacttaacca gtcgcatatc tagtcaagat
    36661 gaacgacagc aaatgactgc tacggtaggt tatttagaat caggtcagga tcgttttgtg
    36721 tataatacga cccctatttc ttaccagcag tttttgaaag atccaatcat cattgttata
    36781 acaccccaat caactggtcc acagtccatt ttgttttgga tagacgcagt acagaactac
    36841 gttctcttta atcaattgtc tgatgcccag gagcttatcc agagacaagg cattgaaaat
    36901 tgggtctcag aaatgcaaac aggttaccac aactacatca cattattgga taatatccag
    36961 agggaacgtt gggtaatgct agcaggagct gtgcttggga ttgcaacttc aatcttgttg
    37021 tttaacacta tgaataggct ctactttgaa gaatttagac gtgccatttt tatcaaacgc
    37081 attgcaggtc tcaggttctt agaaatccat cgcacttatc tctttgctca actgggtgtg
    37141 tttttactgg gatttgttgc gagtgtattt cttcaggtag agataggagt tgctttctta
    37201 gtcttgttac tctttactgg tctatctctt ttacagttac atgtccaaat gcagaaagaa
    37261 aacaagatgt ccattcttgt tttgaaggga ggttaatatg attgaactta aacaggtgag
    37321 taaatctttt ggagaacgag agttattttc gaatctttca atgacatttg aggctggaaa
    37381 agtctatgcc ttaattggtt caagtggtag cggaaaaaca accttgatga acatgattgg
    37441 gaaattagaa ccttatgatg ggacgatttt ttaccgaggt aaagacttgg ccaattataa
    37501 atcgagtgat tttttccgtc acgaattggg ctacctcttc cagaactttg gcttaattga
    37561 aaaccaaagt attgaagaaa accttaagct aggtctcatt ggtcaaaagt tgagtcggtc
    37621 ggaacagcgg ttgaggcaga agcaggcttt agaacaggtc ggcctggctt atcttgacct
    37681 agataagcgc atctttgagt tatcgggcgg agaatcgcaa cgggttgcct tggcaaaaat
    37741 tatcttaaag aatccaccct ttattctggc agatgagcca acagcttcaa tagacccagc
    37801 aacctctcag ttgattatgg agattttgct atctcttcga gatgataata ggctaatcat
    37861 tatcgcaaca cataatccgg caatttggga gatggctgat gaagtgttca cgatggatca
    37921 tctgaaataa aaatccttgt ttttaattgc acgatgagtt actgaaatat tatcatgaat
    37981 caagaattgg agttaattta gaattgtact ttattaatat tgaggtaact ttttcttgat
    38041 aaaggaagaa ataatggaga ggaagttaga atgaaaaaat tcgacaatta tattattgag
    38101 aagccttgcg attctaattc agataaactg caaaaaatct taataattga aagtttggta
    38161 gatgatattt tgcaattttc tctcagaatc aataatagtg taggagagat tttcctccta
    38221 caaccgtttt aaaagaaaac tatctttatc ccaaatcatt catacctctc tcaa
//
LOCUS       DAVHLA010000014        38231 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVHLA010000014 DAVHLA010000000
VERSION     DAVHLA010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38231)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38231)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38231
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.014"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(<1..1007)
                     /locus_tag="VVO77_000854"
     CDS             complement(<1..1007)
                     /locus_tag="VVO77_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HEU5692895.1"
                     /translation="MNKKKMILTSLASVAILGAGFVASQPTVVRAEEAPVAKQSQAER
                     DYDAAMKKSEAAKKEYEEAKKDLEEAKAAQKKYEDDQKKTEEKAKLVQKADEERQKAN
                     VAVQKAYLKLREAQEQLNKSPNNKKNAAQQKLKDALAHIDEVTLKQKEAEANFNKEQA
                     KVVPEADKLAETKKKAEQAEKKEPELAKKVAEAKAKAEEAEKKAVEAKQKVDAEKYAL
                     EAKIAELEYEVQGLEKELKEIDESDSEDYIKEGLRAPLQSKLDAKKAKLSKLEELSDK
                     IDELDAEIAKLEKDVEDFKNSDGEQAEQYLVAAKKDLDAKKAELENTEADLKKAVDEP
                     ET"
     gene            complement(1296..1574)
                     /locus_tag="VVO77_000855"
     CDS             complement(1296..1574)
                     /locus_tag="VVO77_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692896.1"
                     /translation="MYNDVIERISLYEFIGDIFYSKIISCCIVARDLSKNTMKLDVIF
                     FEDKNKRSAVLGLRRDKSGVFKSVTLHFTSAKKYAKVRKTDVKEMKWL"
     gene            complement(1559..1798)
                     /locus_tag="VVO77_000856"
     CDS             complement(1559..1798)
                     /locus_tag="VVO77_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692897.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     DLYKITRDYASQTKPAIQAGVFILEDFRNILCTMM"
     gene            complement(2931..3659)
                     /locus_tag="VVO77_000857"
     CDS             complement(2931..3659)
                     /locus_tag="VVO77_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692898.1"
                     /translation="MNNVDKIRKIHIIVCWVYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IGEDFATKLTNEYKKISQFRSKVSQSSWIKYLEISSFILTIFPSILYGTVDNRVLALI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKAKEYELFKNSK"
     gene            complement(3656..3988)
                     /locus_tag="VVO77_000858"
     CDS             complement(3656..3988)
                     /locus_tag="VVO77_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEU5692899.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAYLSKRACQGICVALAMSSGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGKIAYCIGYGALNRGCDISGNPYPWD
                     GFISATVR"
     gene            complement(4044..4946)
                     /locus_tag="VVO77_000859"
     CDS             complement(4044..4946)
                     /locus_tag="VVO77_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692900.1"
                     /translation="MIRKLIIFLLMLPLFVLWLELHLLVSNLQLNLEIPLDFVVSTSL
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWEKEDSFESDLTKTLKDKIQKSELSYSDLMSLQLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLLYEMSISNNNNWSNKVDKIRIHLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            complement(5154..5528)
                     /locus_tag="VVO77_000860"
     CDS             complement(5154..5528)
                     /locus_tag="VVO77_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HEU5692901.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGFSILRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            complement(5905..6882)
                     /locus_tag="VVO77_000861"
     CDS             complement(5905..6882)
                     /locus_tag="VVO77_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692902.1"
                     /translation="MKNKRYFFDTILIILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLISFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKKNCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINNPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYIGIKHVSIRR"
     gene            complement(7197..8255)
                     /locus_tag="VVO77_000862"
     CDS             complement(7197..8255)
                     /locus_tag="VVO77_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692903.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIDSKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREISLLLATIIVYFFTHRILPFSVFTFMFSYILLFVQ
                     SYLGGNTAWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNFTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALRDLSKQYLNKNISELQDGSFEGGIQDAVASKQIVVINEFIACLNSRCMPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            complement(8412..8657)
                     /locus_tag="VVO77_000863"
     CDS             complement(8412..8657)
                     /locus_tag="VVO77_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000513491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692904.1"
                     /translation="MGIYGRKTIAMKHFFAGIGEIHFLLFLLYLSMSASPIIGLVIGY
                     TKINLINSIIIALGMILALILVLSRVYRKYFYRDDDD"
     gene            complement(9137..9349)
                     /locus_tag="VVO77_000864"
     CDS             complement(9137..9349)
                     /locus_tag="VVO77_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000973716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692905.1"
                     /translation="MLIVLISVIVALLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLLLSFLKKLQTK"
     gene            complement(9503..9998)
                     /locus_tag="VVO77_000865"
                     /pseudo
     CDS             complement(9503..9998)
                     /locus_tag="VVO77_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424410.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(9976..10314)
                     /locus_tag="VVO77_000866"
     CDS             complement(9976..10314)
                     /locus_tag="VVO77_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HEU5692906.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     EKINGTRITK"
     gene            10780..11643
                     /locus_tag="VVO77_000867"
     CDS             10780..11643
                     /locus_tag="VVO77_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU5692907.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYIRQHGAGELSDHAEQVVKKLWRKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKK
                     EVEIYYQAKER"
     gene            complement(11829..12299)
                     /locus_tag="VVO77_000868"
     CDS             complement(11829..12299)
                     /locus_tag="VVO77_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HEU5692908.1"
                     /translation="MRMPLKHPLKNRKKEKNMSKEKVILAYSGGLDTSVAITWLKKDY
                     DVVSVCMDVGEGKDLDFIHDKALKVGAVESYVIDVKDEFATDYVLVALQSHAYYEQKY
                     PLVSALSRPLISKKLVEIAHQIGATTIAHGCTGKGNDQVEYQIAVAKKANEAKK"
     gene            complement(12265..13071)
                     /locus_tag="VVO77_000869"
     CDS             complement(12265..13071)
                     /locus_tag="VVO77_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU5692909.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSIPYYTAKNKLIVKKSDLTTYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVSKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            complement(13278..13919)
                     /locus_tag="VVO77_000870"
     CDS             complement(13278..13919)
                     /locus_tag="VVO77_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5692910.1"
                     /translation="MIELKNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLPKKDKLKKVEEILERVGLSATLHQRVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRVIELGEGK"
     gene            complement(13916..16024)
                     /locus_tag="VVO77_000871"
     CDS             complement(13916..16024)
                     /locus_tag="VVO77_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU5692911.1"
                     /translation="MKKISNFCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLIFNYVMKIGTTILLTAL
                     LIGVGRSLEQENKELAYQQQWVSQGNYLTLETFKLNDNLWQEELAGSGKSTDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVTTFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            complement(16076..16372)
                     /locus_tag="VVO77_000872"
     CDS             complement(16076..16372)
                     /locus_tag="VVO77_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEU5692912.1"
                     /translation="MIGEINHEKISVASLMVCGILATTNALAVWVEGGQWNYGVGWTG
                     TFGYSDYLHSTRYHTATVRHGGRTSKDYAKPEAWARASLTKIPPTGMEYFYGFE"
     gene            16777..17097
                     /locus_tag="VVO77_000873"
     CDS             16777..17097
                     /locus_tag="VVO77_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU5692913.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVPIGICRDDAKLIQKGFSLLELTEETSMLSHLKKEVEIYYQ
                     AKER"
     gene            complement(17149..17736)
                     /locus_tag="VVO77_000874"
     CDS             complement(17149..17736)
                     /locus_tag="VVO77_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEU5692914.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQKLVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            17978..18649
                     /gene="sdaAB"
                     /locus_tag="VVO77_000875"
     CDS             17978..18649
                     /gene="sdaAB"
                     /locus_tag="VVO77_000875"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEU5692915.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            18658..19530
                     /gene="sdaAA"
                     /locus_tag="VVO77_000876"
     CDS             18658..19530
                     /gene="sdaAA"
                     /locus_tag="VVO77_000876"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEU5692916.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            19552..20184
                     /locus_tag="VVO77_000877"
     CDS             19552..20184
                     /locus_tag="VVO77_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU5692917.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            20234..20491
                     /locus_tag="VVO77_000878"
     CDS             20234..20491
                     /locus_tag="VVO77_000878"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692918.1"
                     /translation="MKIKEQTRKLAAGCSKHCFKIVDGTDEVSSKHCFKVVDGTDEVS
                     SKHCFEVADRTDEVSSKHCFKVVDGTDEVSNHIRQGDVDVI"
     gene            complement(20577..22427)
                     /locus_tag="VVO77_000879"
     CDS             complement(20577..22427)
                     /locus_tag="VVO77_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEU5692919.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVARAVDEAKVPKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(22469..23626)
                     /locus_tag="VVO77_000880"
     CDS             complement(22469..23626)
                     /locus_tag="VVO77_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU5692920.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKEDIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVINNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKGTIIYLDKISQINQNML"
     gene            23684..24850
                     /locus_tag="VVO77_000881"
     CDS             23684..24850
                     /locus_tag="VVO77_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HEU5692921.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPSVAALLLIDILMTVALFTVDRADKIL"
     gene            24989..25315
                     /locus_tag="VVO77_000882"
     CDS             24989..25315
                     /locus_tag="VVO77_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEU5692922.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            25302..25895
                     /locus_tag="VVO77_000883"
     CDS             25302..25895
                     /locus_tag="VVO77_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEU5692923.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYATRFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            25888..26799
                     /locus_tag="VVO77_000884"
     CDS             25888..26799
                     /locus_tag="VVO77_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEU5692924.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            26862..27926
                     /locus_tag="VVO77_000885"
     CDS             26862..27926
                     /locus_tag="VVO77_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692925.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIANLDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIETPEGGEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLKSPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(27998..28858)
                     /locus_tag="VVO77_000886"
     CDS             complement(27998..28858)
                     /locus_tag="VVO77_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HEU5692926.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYESIARLDYAKFLEVLPPSFYHQLDANQIEVQPILD
                     KDFKTLAQEK"
     gene            complement(28980..29966)
                     /locus_tag="VVO77_000887"
     CDS             complement(28980..29966)
                     /locus_tag="VVO77_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEU5692927.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(30238..31713)
                     /locus_tag="VVO77_000888"
     CDS             complement(30238..31713)
                     /locus_tag="VVO77_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HEU5692928.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(31797..32720)
                     /locus_tag="VVO77_000889"
     CDS             complement(31797..32720)
                     /locus_tag="VVO77_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU5692929.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(32734..33663)
                     /locus_tag="VVO77_000890"
     CDS             complement(32734..33663)
                     /locus_tag="VVO77_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU5692930.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(33982..34332)
                     /locus_tag="VVO77_000891"
     CDS             complement(33982..34332)
                     /locus_tag="VVO77_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692931.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKALTDDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETADKDVLENSQEELQKAVLFLADEKGSEHTEAELI
                     DNLKEVIAKLKANA"
     gene            complement(34758..34913)
                     /locus_tag="VVO77_000892"
                     /pseudo
     CDS             complement(34758..34913)
                     /locus_tag="VVO77_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(35098..35709)
                     /gene="rpsD"
                     /locus_tag="VVO77_000893"
     CDS             complement(35098..35709)
                     /gene="rpsD"
                     /locus_tag="VVO77_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEU5692932.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(35904..36956)
                     /locus_tag="VVO77_000894"
     CDS             complement(35904..36956)
                     /locus_tag="VVO77_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEU5692933.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKGQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(36953..37651)
                     /locus_tag="VVO77_000895"
     CDS             complement(36953..37651)
                     /locus_tag="VVO77_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU5692934.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(37818..>38231)
                     /locus_tag="VVO77_000896"
     CDS             complement(37818..>38231)
                     /locus_tag="VVO77_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat-containing
                     protein"
                     /protein_id="HEU5692935.1"
                     /translation="ATVNVYGNKDGKPDLDNIVATKKVTIKINVKETSDTANGSLSPS
                     NSGSGVTPMNHNHATGTTDSMPADTMTSSTNTMAGENMAASANKMSDTMMSEDKAMLP
                     NTGETQTSMASIGFLGLALAGLLGGLGLKNKKEEN"
BASE COUNT        11958 a         7932 c         6366 g        11975 t
ORIGIN      
        1 gtttctggct catcaactgc tttcttaagg tcagcttcag tattttctaa ttcagctttt
       61 ttagcatcta agtctttttt agctgcaaca agatattgtt cagcttgctc accgtctgag
      121 tttttgaaat cttctacatc tttttcaagt tttgcaattt cagcgtctaa ctcatcaatc
      181 ttatcactca actcttcaag ttttgatagt ttagcttttt tggcatccaa tttagattga
      241 agaggagcac ggagaccttc tttaatataa tcttctgagt cagactcatc aatctctttg
      301 agctcttttt ctagtccctg aacttcatat tccaactcag cgattttagc ttcaagagca
      361 tatttttcag catccacttt ttgtttggct tcaacagctt ttttctcagc ttcttctgct
      421 tttgctttag cttctgctac ttttttagca agttctggtt cttttttttc agcctgttct
      481 gcttttttct tagtctcagc taacttatct gcttcaggaa ctacttttgc ttgttcctta
      541 ttgaaattcg cttccgcctc tttttgtttt aatgttacct catcaatatg agctaatgca
      601 tcttttaatt tctgttgagc ggcatttttc ttattgtttg gacttttgtt caattgttct
      661 tgtgcttctc ggagttttaa atacgccttt tgaactgcca cattcgcttt ttgacgctct
      721 tcatccgctt tttgaacaag ctttgctttc tcttcagttt tcttttgatc gtcttcatat
      781 tttttctgag cagcttttgc ttcttctaaa tctttcttag cttcttcgta ttctttctta
      841 gcagcttcag attttttcat tgctgcatca tagtctctct cagcttgaga ctgcttagct
      901 acgggagctt cttctgctct tacaacagta ggctgagacg caacaaaacc agcccctaag
      961 atagcgacgc tggctagact tgttaaaatc atttttttct tattcatcta aatttacctc
     1021 ttttctgata gtcattttta gactatactt atattaagta tactcccccc gtaaatattt
     1081 gtcaaatgtt ttatattaca tttttattac aaatttctat atcataagct tctactccaa
     1141 aaaatagata aagatactac ttttgccctt ttcgattctc tttttaaaca tagcatcatc
     1201 ttccttcatt cctataaaaa catttccgat gagagagctt gttttttaat ttcgttaaac
     1261 aacaaaaaac gcaagcttaa gcctgcggac aatctttata gccatttcat ttctttcaca
     1321 tctgttttac gaactttagc atatttctta gcgcttgtaa aatgtagagt aactgattta
     1381 aatactccgc ttttgtctct tcgtaaacct aaaactgcgg atcttttatt tttatcctca
     1441 aaaaatatga cgtccaattt catagtattt ttagataaat ccctagctac gatgcaacaa
     1501 cttattattt tagaatagaa aatatcaccg ataaactcat ataaagatat cctttcgatt
     1561 acatcattgt acataggata tttctaaaat cttctaaaat aaaaacacca gcttgaatag
     1621 caggttttgt ttgactagca taatctcgtg tgattttgta taagtcaaat aaatgatgta
     1681 aatcagtcaa gcaaaaattc actttgaaaa tctctaaata cttataattc gttgatactt
     1741 gacatgtttt tccattgaat ctttcttgat agtccaaaat acaatcaagt aatttcaacg
     1801 acaaactcca tattttctca aaataaaaaa gcacggggca gttctcacta ctgcccaaag
     1861 tggttgatta gagtcggctt ctctaactcc ctatgttgtg cttattaggc ttatcgcaag
     1921 ggaacagttt ttagctctgc caagccacat agtgtgctta ctactatgtg tccatgtcac
     1981 catgaattgc cgaacggttt aacgagaaag tatagtagat tgaaacaaga tgtgaacaaa
     2041 tcgattagga aagtcaaatt aatttctaga aatattttaa cagtcataac ggactattcc
     2101 agattcaatc tactatatta cttttaggtt tatcccaact caattatgac atttttttca
     2161 aaagtcaata tatctcactc ttttcaacga caagaaagag gctgataatc gaccaacctc
     2221 tgtttttaga tacagttcaa gtccaaacta ttctttatag aaaagtccga taaattcgag
     2281 caatagttaa catacttaca aatataactc ccaaaataga taacactatt ttcacaaaac
     2341 tcagttccga acctatgaca tatatatgaa aaagaagggc tagtcctaca catatataca
     2401 ataagtagcc aacaagtttt atctcaccaa ttcctgcaaa aaaatgtttc atgtgacgat
     2461 tctccattta ctccattaaa tcagttttat tttagactat cataacacaa tcacctcttc
     2521 aataaaaacc atttgcgaaa tactattctg aagcattgat agctcagatt tctcagaata
     2581 gagctgtcct aactatcgag cagctcaaat acatatatat gagcaattct aagcctagaa
     2641 ttgctataaa ataaatgttt ccaggctatt ctaagtcttt gactgcttaa aattttacat
     2701 tctgaaggat tctaaagcta gaacagctca aaatcacgag aactaaggta ttcgaaactt
     2761 cagagtaata caatccccat aggaattctc cattcttatt aagcatgatt aaaatgtaat
     2821 cctaacaagt gatcctcgac tgtgtttgta gcacttagtt acctagataa gactatttcc
     2881 ctttatcata tctgatttta agccgttcta agatttaacc tatgtttcta ttacttgcta
     2941 tttttaaata attcgtattc ctttgctttg ataaatggaa ctgaaaaatt agaaaaaaga
     3001 agtaaaaccg aaaacaaata gcctgctttt tgaatcacta aaagatatcc taaaaataag
     3061 taagctataa catccaatgc gaaaagaaaa aatattctcc tcttcattaa agtacttgtg
     3121 tcaaataatc tgatgaataa aaattttatc gtagtatcta cacaaatttt tatcaaaaag
     3181 ataagagcca atacacgatt atcaactgta ccgtaaagaa tagatggaaa tatagttaat
     3241 ataaaactag aaatctctaa atattttatc caagaagatt gagacacctt gcttctaaac
     3301 tgactaattt tcttatattc gttagtcaat ttagtagcaa aatcttcccc aattaaatga
     3361 aagattgcta actctaggat aaaaacactt attaatacgg tataagtcaa aaaactttct
     3421 gggaaaaact tattgattaa aatggggaaa ctcattaaca gaatcgaatt tatggctaga
     3481 cagatagata ctattttatt tttcacagaa tatagaggta gtgatactat tgagtagata
     3541 aaagctaaaa aaataagcaa aaaatactcc gtgtcattta taatcgccct gaatgataaa
     3601 aatatataca cccaacatac gataatatgt atttttcgaa tcttatctac attattcatc
     3661 ttactgtcgc agatataaat ccatcccaag gataagggtt cccgctaata tcacaacctc
     3721 tattaagagc accatatcca atacagtaag ctatttttcc tgctgctgca ccaataagcc
     3781 agcctccaag acctccaacc ttaatatagt ttattagttt tttggttaaa actgcagctc
     3841 cagctaatgc tataaaagtt cctgaactca tagctaaagc tacgcaaatt ccttgacaag
     3901 cacgcttgct taaataagct cccccatcaa gatacatcat ttcttcttca tcaatcacaa
     3961 cataattatt tggtaataca agttccattt gttttctcct ccttagttga aattgtttca
     4021 tttgttttac aaataggacg aacttaaact atctttttat tactcagtaa taatttccga
     4081 gatttcattt tatgatactc tctattcata cagaaatcaa aattttgcct taaccaactt
     4141 gtataataga aaaaatctaa ttgattgatt ctgatgaggt gtatcctaat tttatcaacc
     4201 ttgttggacc agttgttatt gttactaata gacatttcat acagcagtaa ctcgacaaga
     4261 cctgtacaca gaagggtgtt atgagaatct tcgatttttt tcaaaatatc ctcaaaaagt
     4321 tcactatccg ttaaaaaggt ggattggttc atcgcatcat acagctgaag agacattaag
     4381 tcagaataac ttagctctga tttttgtatc ttatccttta acgttttcgt caaatcgctt
     4441 tcaaacgaat cttctttttc ccatttattt tgattaaaaa gaaattccgt cttattaaaa
     4501 acgagatgat tgatatccat tatagtccag aaaaatattg tagtaagcat gatgattgca
     4561 aaaggaattt ttaaaataaa tactagaata atagcaattt caagaataaa actccatata
     4621 atcctagatc ttaaatcatc aggcgacaaa cttttacgat ggaatgaaaa atagggcgag
     4681 aacctcacat ttactttctt cctgcctata aaaataaaag gaaaaatcgt aataagagct
     4741 tctttcttgt acaaatcttt caatgcgtat agtatgtcta aaactatttt tgataaaatc
     4801 aaactacaga aagcaagact cgtactaacc acaaaatcaa ggggaatttc tagattcaat
     4861 tgcaagttac tcactaacaa atgcaactct agccacaaga caaaaagagg gagcattaat
     4921 aaaaaaatga ttagtttacg tatcataatt ttacagtgtc cttatcattt tcttaatttt
     4981 ggataaatta tcattgctat gattaaaatc aaaaaaacga cattcatcca aataatcaac
     5041 ttttttattt cttcgctaac aaaatcatag gctaaaaaaa ttatggatga tataaataga
     5101 catacaaaaa aaataataac aaaaattttt tccattttaa tacccatatc tagttaccac
     5161 aaggcgttta aatttgggtc tctcctattt acatcattgt tggcccagat tgttgtaata
     5221 gcatcgccaa ttgacatcca agctgcaaat ccattaatag cagacagtgc aaatcctgcc
     5281 actctatttg caactcgtac cccaacatat cttgcagctg ctccagcaat tgcgcttgta
     5341 actcgccgca aaccataatt acgaatataa tttctaacta gactgattgc tcctccacct
     5401 aaaacaccat taaaagctat attaatggct gttgcaacag gccatctcag aatagaaaat
     5461 cccccatcaa gatacatcat ctcttcttgc tcaagagcaa cataattatt tggtaatacg
     5521 agttccattt attttctcct tttttattaa gcatagttag gatcgtttcc taacaagtga
     5581 tagacgactg tgtttttatc acttagctac ctagataaga tatcctttct ctaccttatt
     5641 tgtttttata ggttacctaa ggtttaaaat caattattgt ttgaaactta acagttctaa
     5701 accactagca ataaatgatt gcgaactcac taatactatt tcaaaattta ttttttttga
     5761 cttagtaacg caattccaat tagcaataca cctaatataa ataaaagtat ttcccaaaat
     5821 ttattctcag ttttaataag tggaataaga tacatactga ctaatatgca acttgcccct
     5881 ataatggcaa atattattct agttttatct cctaattgaa acatgtttga tccctatata
     5941 cacttcaagc aaaagttgga tttctgaaat ggctaaagat aaagataatg gttgcgagct
     6001 atttaaacta tcatcaatat tctgctcgat taaaacaaag tctggtctta cctctaaaat
     6061 tttctttaac attgattcat atttattttt ttcattataa tgccgtaaat atagatttaa
     6121 ttttataaca tccaacatac cataaagtga tattggatta tttatttttt taaatcgctt
     6181 aacttctaat aaatcaattt gttcacgcac actctctgaa agatatggct tgattaaact
     6241 gatataagat aaagccacgc atggcaactc agattttgat tgcaatttcc aaatttcatg
     6301 ataatcctga agattaaact cacaattctt cttagattcc agtattgtta gtacctttga
     6361 ttttaacaga aataattgtt gattctcaat tctataaagt ttttgtacta atgctatgat
     6421 aatagaaaat gaaataagag gcaaaagcaa cggtttgtca tacacaaaag taaagaaaaa
     6481 atagtatgaa attagtgttg taaagtacaa gaagtagtaa aatttaaaca gattcttagt
     6541 tgtttgactc tccttataaa acactgctat tcctggacta aatcccatta gttggtgaaa
     6601 gagaattcga tagtatttcc tagctcctat aatgatcaca aatataaaat aaaaataaat
     6661 tggtcttaat ttacaaaaga ttgaggaaac tagtaatagc aaagtatgta agcattgaga
     6721 caaaatatag aataacggta tcgccaatac aaaggttaag atggcatgag agggagttcc
     6781 taagatgtcc aattttataa atactgggct gacacaaaat atcgtgctta taagcagtaa
     6841 aattattaaa attgtgtcaa aaaaataacg cttatttttc atttagtcta ctttccattg
     6901 ttaaataata ctactgttaa caccaagcca acttagcaca ttgcatcacc taatcctacg
     6961 ctacttgtcc ataatccttt aatgtttcta ctaaaattat tccaatctcc cccatcaaga
     7021 tagcttattt atcctagaca acgcctactg caacagtata aataagattc atcagccatc
     7081 ttttctggca atcatatggg tagactaatg atatttctag ttactcaaaa atatctagct
     7141 atactagagt tatttctaat ccctaggaca cttgttaatc caaatgtaac aaattttcac
     7201 cccttaatag gactctttct ggaaaaaata taaggtctat ctttataaaa aaatctatca
     7261 tattgggatg gcatgcatct ggaatttaaa caagctataa attcatttat aactactatt
     7321 tgtttagagg caacagcatc ttgtataccg ccctcgaaag aaccatcttg taattccgaa
     7381 atatttttgt ttaaatattg ttttgacaaa tctcttaatg cttcattatc gtaaatgatt
     7441 cccaaaaatc caaccttata tagtaaataa tttaaactta caaagtaatt gaatcccata
     7501 gtatattttt ctttataaag caaaggtaaa actttataaa aaatatctaa gtcaacctca
     7561 ctctgattct gaagcaagta ggagtcaagc aaattttcaa aaatagctaa caatatgatt
     7621 ggtgtaaagt ttttgtattc acatgtcaag tattctgagt atcgtgcaga tgatatttct
     7681 tttatataac tttttgaaag caagattttt tcaaattcat catctattat taatcttcta
     7741 tttccaatcc aagcggtatt accacccaaa taagattgta caaatagcaa tatataagaa
     7801 aacatgaacg taaatactga aaaaggtaga attctatgcg taaaaaaata gacgataatg
     7861 gtagccagga gtaaagatat ctctcgtgac aatcgaattc ttttcagcat cttttttaac
     7921 agtccgtaag gttgtccttg gcaatattct tgaactaaat taatcggaat gacatctctc
     7981 accatttctg gaaagtagag taagtttata ggttgaaatc tccagctccc atcataagta
     8041 aatggatata gaaccaaata cttaaaagat ttttttctta taaacttaat tatcacaata
     8101 tgaatgactg ttgcaatgaa gtatattaaa tataaaagta aaaccgccat caatatactt
     8161 acaaaaatcc ccttggaatc aatcaatgga aaataaaata ttgcaactag aagcgaataa
     8221 agtcccgcta ataaatattt ctgatcatct ttcattcaaa acaccatatt atttactaag
     8281 aatgcatcaa tacaatagag caactctgta agtcaatatt tgataaagca aagctttaaa
     8341 cccttcccca gacgttagct tttattcaac ccactacagt tgacaaggag cccaaattat
     8401 tgataaaaac tttagtcatc atcgtctcta taaaaatatt ttctatacac tcttgataat
     8461 accaaaatta atgccaatat cataccaaga gctataataa tagaatttat tagatttatt
     8521 ttagtatatc caatcactag tccaataatt ggactagcag acatgcttag atataataaa
     8581 aataacaaaa aatgaatttc accaattcct gcaaaaaaat gtttcatagc tatagtttta
     8641 cgcccataaa tacccatcaa atttaccgtc tacgatatct aaaccatatg caatggctcc
     8701 tcctaatgag aagacttcag caacagtagc cgcaatatta agagcattag taatagttgc
     8761 catactaact ccaccaatat atcttgttat agcacttagt tacctagata agatatcctt
     8821 tagcttgctt ccaaaattta agtctacacc tataatatga gttcatatta gtactgctaa
     8881 atcctatcta tagtaatgtc aaacacctaa ataaagtcat ctctccaatt cattcaagaa
     8941 atgaagaaag gcaaaaaatc tttaaaataa gaaaaatgca tattatcagg tgttcaaaaa
     9001 tattgatgat atacgttata tagatagaaa gatttactca atctcatttt caaattgagt
     9061 tttttcccag cctcattttt aatttatatc ttcaatagaa tctaatgacc gagctactgt
     9121 attacacaga ttaatattat ttagtctgta atttttttaa aaaacttaat agtaaatttg
     9181 ctccactgat tgctatcaat atttcaattg gtaaaaaata gtaattccaa ataaaatgag
     9241 aaatcagcaa tgatagaaaa ataacaatat caattttcct gttgttgaca tactctgtaa
     9301 ttttatgata cagtaatgca acaataactg aaattaaaac aatcaacata atactattat
     9361 cctatccttc tcactaactc tatttccaaa atttaatttt tgggggactt agtaatgaaa
     9421 ttacaattaa caacacacct aaaataaata aaaatatctc ccaaacttta ttctcagttt
     9481 taataaagct accatatcta tctcatttct tatttttaaa taattcatac tctttttctc
     9541 tgataaaggg aactgaaaaa ttagaaaaaa ttatcagaat tgaaaacaga tatacgtctt
     9601 tttgtatcac taaaacataa cctaaaaata tatagaccat caaatctagt acaaaaagag
     9661 aaaatatcct ccttttcatt accttacttg ccttaaagat tctgtttaat agaaccttta
     9721 tcgtagtatc tacacaaatt tttatcaaaa agataagagc caatacacct gctgctgcac
     9781 caataagcca acctccaagg cctccaacct taatatagtt tattagtttt tttgttaaaa
     9841 ctgcagctcc agtcaatgct ataaaagttc ctgggctcat agctaaagct gcgcaaattc
     9901 cttgacaagc actcttgctt aaataagccc cccccatcaa gatacatcat ctcctcttgc
     9961 tcaagagcaa cataattatt tggtaatacg agttccattt attttctcct ttatactatg
    10021 taataccaca aaatgatttt gacctaaatc attcttaact tgaagaatcg caggaaatgt
    10081 taattttgga gtcaaatctt ccagtgccac tcgaacagct tttactgtaa aattcaactt
    10141 attcagacct gaaacaatac cactgacagt cgttccatac atgtctgtac caataatttc
    10201 ccgaatcttc atgattgata gttccttttt gtaagataaa agaactgttg aaacaactgc
    10261 cgcagcacaa tctgactgat catgttgcat cgtacaagga tattttttta acatagaaat
    10321 actcaattct ttagaattaa tctaactttt ctttgatgtc acccaaacct caatcactgc
    10381 ccagtagttc ttgaatcagt ttattttcaa tcgtatcatt ctttgttctt gatatctttc
    10441 caagcattgt agtacagcag atttttgtcc aaggactgag cctcctttaa caactcaagc
    10501 tcccttacat tatatcgacc agccccatgg aaagattatg accagactaa tcaatgatat
    10561 catacatact agaatacaaa atattttttt attcatactt tttctcctat ctttattttc
    10621 tacctacatc atacctctta ttaagctcat tttaaaatta cgttaacttt tttcacaaat
    10681 ttatttcgac tttctttttt actttttaca ttgctatgat acaatatttt taacaagatt
    10741 ttattatttg ttaacttttt tcacagaaag gagaaaatca tgcgttatga tttcggaaag
    10801 gtctataaag aaatacgtga gtcaaagggg ctgacccaag aagaggtctg tgggggtgtt
    10861 ctctcaagaa ccagcttatc aaaaatcgaa agtggcaaga caaccccaaa atatgaaaat
    10921 atggaatttc ttctccgtca aatcaatatg agttttgaag agtttgaata tatctgtcaa
    10981 ctttatcaac caagtcaacg cacagagatt atgcaaacct atctcaatat gcgttccatt
    11041 atcgggacca gcgatcttgt caatttattt caaaaatgcc aagactacct caagacccac
    11101 cacgatctcc ctatagaaga aatcagagat atgcttgaag ttgtcattta tatccgtcaa
    11161 cacggggcag gggaactatc agatcacgca gaacaggttg tcaaaaaact ttggagaaaa
    11221 attgaaaaac aagatacatg gtatgagagt gatctaaaaa tcctcaatac cattcttttc
    11281 agttttccca ttgaatacct ccatctcatc actggaaaaa tattgcaacg cctagaagtc
    11341 tataaaaact atcaacattt atatgacttg cgaatagcaa tcctgctcaa cctttccaca
    11401 ctctatctat acaatcaaga taaaaacatg tgtaagcaaa tctgctacac tttactggag
    11461 gacgccaaga ataagaaaag ctacgatagg ctggctatct gctatgtccg cattgggatt
    11521 tgtacagacg attctaaact tatccaaaaa ggtttctcac tcctagagct gaccgaggaa
    11581 acttctatgc tgtctcatct caaaaaagaa gtagagatct attaccaagc gaaggaaaga
    11641 taaaaaagcc gagggagctc ctcgaccttt tcatagaatc gccgaacgat ttaacgagaa
    11701 agtatgactt ttacgtttat cccaactcaa ttatgacatt tttttcaaaa gtcaatatat
    11761 ctcacttttt caacgacaag aaagaggctg ataatctacc aacctcttat tctgaaccca
    11821 tcactccatc actttttagc ttcattcgct ttcttagcga ctgcaatctg gtattcgact
    11881 tggtcattcc ccttaccggt acaaccatga gcaattgtag tcgctcctat ctgatgcgct
    11941 atttcaacca attttttaga aatcagaggg cggctcaagg cagataccaa gggatacttt
    12001 tgttcataat aggcatgtga ctgaagagcc actagcacat aatctgtagc aaattcgtcc
    12061 ttaacatcaa tgacataaga ttctactgcc ccaaccttaa gagccttatc atggatgaaa
    12121 tctaagtctt tcccttcacc cacatccata caaactgaaa caacatcata gtctttcttt
    12181 aaccaggtaa tagcaactga tgtgtccaaa ccgccagaat aggccaaaat tactttttct
    12241 ttactcatgt tcttttcctt ctttctattt ttcaatggat gctttaaagg catcctcaat
    12301 gagtttgtct aattccccag actccttcaa cttttgaatg gttttatcga ctgcctcttt
    12361 caattccttg ctatcttttt tcatggctac cgcgtaggaa tcatcttgct ctttttcaaa
    12421 attgaggtct gcgattgcta aatcaggatt attttccaca aatcccttgg aaacaggttc
    12481 ttcaaagata acggcatcca cttgtcctga ttttaaatct gtgattaaat tcccattttt
    12541 aggcagagat acgagggaag aattttgtag caaatctttc gccatcgtct cttgaatcga
    12601 acctttctgc gctccaacct ttttctgcgc caagtcgttt acagactgat aagtagtcaa
    12661 gtcagatttt ttgacaatga gtttattttt tgcagtatag tagggaatgg aaaagtcaaa
    12721 caccttgctc cgttcatctg tcttagaaac acctgatatg gcaaggtcgg cttttcctga
    12781 ttgaacacta gccagtacat tatcaaaact catgggagat agttccaatt cgacacctag
    12841 ttctgttgcg atagccttgg ctaattcgat atctgaaccc acaatctgat ttttcccatc
    12901 aaccactttt tggtattcaa atggagcaaa atccggattg agggctacaa ccaattttcc
    12961 tttggacttg atggcttcaa ttccagccga ttgattgttg ctacaagcaa atagtagggg
    13021 gagcatcact aaaccaaaca tcgtcatcaa caccttcttc atcttattca taataaagcc
    13081 tactttatgt ttattccttt tgtttgtata aacaatacat ctatattcat cctttgtcaa
    13141 gcctaaattg aaaaaatttt caatttgaaa caaaaaaaac ctagaaatac tacataaaat
    13201 gtcattccta ggcgtattta tgctattttt ctctggaaaa catgagtatt cagccagtca
    13261 aaaggagctg aatgaactca ttttccctcg cccaattcaa tgacacgatg acattgttgg
    13321 gctacataag catcgtgggt cacaataatg actgttttcc cttctcgatt catctctaag
    13381 agaaacttca agaccaaatc tctattttca ggatccagcg aacctgtagg ttcatcggct
    13441 aaaatcagct ggctgggttt taagatggct ctagcaactg caattcgttg ttgttcgcca
    13501 ccagacaact cggagaccct ttgatgcaaa gtagctgaca aacctactct ctctaaaatc
    13561 tcttccacct ttttgagctt gtctttctta ggcaatttca catatttcag cgccagcatg
    13621 agattgtact cgaccgtttc atcatcaatc agggcaaaat tttgaaacag ataagagata
    13681 tgttcacgga ttattgtttg cgacttagca gaattaaccg ctagatttgt ctgaccaaaa
    13741 atctcatacc gtccgctata atcaccatct atcaaaccca ataaatttaa caaggtcgac
    13801 ttcccactac cactcttacc aacaatagct accaaatccc cctgatcaat cctgagagat
    13861 aagttatcca aaatcacttt tcccccaatg gttttggtaa tatttttcaa ctcaatcata
    13921 agatgccccc tttcaataac tctactagac ttcttttctc catcctagaa gctaagccta
    13981 gcacaaatag tatatccaga catgtaaaac ctgcaaacag tagaagtggt aagaacgcat
    14041 gggcaaagaa aatcaagact agaagaggga aactatagcc cagcaagagc agaacgagga
    14101 gaggacggta gcgatcgacc agtttccacc ccataaactt cttggtaatg atatccctgc
    14161 gcttcaataa gaaagttgtt actagtaaga agtaggaaat catcatgcta aggagaccaa
    14221 acaaagcaaa gagtaggtta aaattccgaa cagcatctct ataagaatcc actttctctt
    14281 gttgaatggc ttgaatagat gaaaatttta aataatttcc atctgacaat ttctcaacta
    14341 actctgtaat ctctttttga tgttgaaccg tattttcaat tttaatcgga ttatttaagc
    14401 cagttgttga cagggaggct ttctcatccc acatcatatc agaatcattg accaagctaa
    14461 taattggatt ggagagattt tcctttcgct tatcactata tgggaaaaat gaccaatctc
    14521 cttcataata ggcaatctcg acatccatct cctctatcgt tcgtttttgc tgctcttcat
    14581 acttcatcga atgaaaggca attaacttcc ccaagagctg atttttatct tcttcacctt
    14641 tcgtacttgc tggcatcaaa ataacttttt taataccggt atctggtagc ttgaatccct
    14701 tgctctttag aaaattgcga ttggcatagt aaacatccac cgtatctgtt aactgatatt
    14761 gctgaatctg ttctgattgg acaaaatttt ttacaggaag actgctactc tgcacatagc
    14821 ccgcctgcgt tttttctacc aaatcctgat aaaatcgata gaaataatct gtagatttcc
    14881 ctgaccctgc tagctcttct tgccacagat tatcattgag tttgaaggtt tctaaggtca
    14941 ggtaattacc ttgacttacc cactgttgct gataagcaag ttctttgttt tcttgttcta
    15001 aacttctgcc caccccaatc agtaaggccg tcagtaaaat agttgtccct attttcatca
    15061 cataattgaa gataagacca aatttgaaag atgaaaaacc tttcagcaga gagctgattg
    15121 tcattttttg gattaagagg taagtcaacc aactgataaa gagataaagc tgcaacagca
    15181 aaaaatgaga caaccacagc ataggaaaca aatcttttgg cttataatca agcaagaaaa
    15241 acacgcctag attgatcaca agagccccac ctaggaggag gtaaaggttg ccttttacaa
    15301 catcagctaa aacagcccta tcttgaaaac caagtaattt ttgtacccca actcttttca
    15361 tctccatcat cggttgatac actgtcacta acacaagaag caaaatagcc aagacaaaaa
    15421 caatggcaga taaaagcaaa tctcgattta tgacttccac tgcacttttg taggtcggct
    15481 ctagcaaggt agcctggtct atcttgaaaa aatcgctcca tttctgtaca atcctatcct
    15541 tgtccatctc ttgtgtagaa gttatcgtat agcgaccatt taaactacga gatgtatcct
    15601 tgatataggt ttgaaaagtc ataagctgaa taggtttggc ttttagaaag gtcggaatcg
    15661 taccaagttt attggaaatt tctttattac tatagactcc ttcaccatct gtggtaaaat
    15721 caagagaaga aatcccaaac tcttggtagg ggaaggtatc tttatcaaaa acaccagact
    15781 tgaccacctc atcaccactg tctgttttga tgatggagac tttatactcc tttgatacat
    15841 cctcaaaaaa tcgaagaaca gacgctgcag gttcgttaat atctttcaaa tacaaatcca
    15901 aagaatctac agtctttccc atttcttgaa tccgaaccac ttctcgtgta tagtttacat
    15961 taaaaacaaa aaaagtggta cacagaagca ggagtaacat acagaaatta ctgatttttt
    16021 tcataaaagt gcctccacta cagttttccc tctccaaata ggagagggaa gaattttact
    16081 caaatccata gaaatattcc attcctgttg gcggaatctt ggtgagggaa gctctagccc
    16141 atgcctcagg ttttgcataa tccttagagg ttctaccccc atgtctaaca gttgctgtat
    16201 gatatcgagt agaatgtaag taatcagaat atccaaaagt tcctgtccaa cctactccat
    16261 agttccattg accaccctca acccatactg ctaaagcatt tgtagtagca agtataccac
    16321 ataccattaa agatgcaaca ctaattttct catgatttat ttctcctatt atcgagagct
    16381 gttccgtaaa aacagctata gtaatttatc aacaagtatc gtagtccatt ggactcacct
    16441 tccttctatc tcatttcatt tttaacaacg aacttactct taaccgggag aatggtgcgc
    16501 ttctgtatca ggtccttgaa caaccagagt agtattaagc acactctaac tattactcaa
    16561 gaatcagtcc aataaacaat atggatagcg ctttcaaatt tttaaactcc tatcccatcc
    16621 ttttatctat ataataagtg aaaatataat aactgtcaag taactgaagt gaattttata
    16681 aaaaaattac aagccaaatt tgtaaagttt acactaagcc gctagggcaa tcgtctatca
    16741 gaatatccgt ttatttgtca ataatccgag aaaatcttgc aacgcttaga agtctataaa
    16801 aactatcaac atttatatga cttgcgaata gcaatcctgc taaacctttc cacactctat
    16861 ctatacaatc aagataaaaa catgtgtaag caaatctgct acactttact ggaggacgcc
    16921 aagaataaga aaagctacga taggctggct atctgctatg tccctattgg gatttgtagg
    16981 gatgatgcga aacttatcca aaaaggtttc tcactcctag agctaaccga ggaaacttct
    17041 atgctgtctc atctcaaaaa agaagtagag atctattacc aagcgaagga aagataaaaa
    17101 agccgaggga tttcctcgac tctttacata ttatttgttc gttagttctt aataccagcc
    17161 attgttaagc cagaagtttt tagcagctgt ccatgaaccg taacgtcctg caacgtaggc
    17221 atctgctaca cgttcttggt tttcagctga gtagtcaccg ttcaggtatg aatctgttaa
    17281 ttggtaacgt ccgatataac gtccatttgt agctgtatag ctaccacctg attctttttg
    17341 agcgatccat tctttggctt ctgcttcaga tccgcttaca gttgaaacaa ctgtttcact
    17401 tactactgga gtttctgcca ctggagctga aacagtttca tcttgagcgg ctggtgccgc
    17461 ataagtagct ggcgctggtg ttgcaacagg cgctacaggg ccatcgataa ccaacttttg
    17521 atcaacataa atcaaatgaa tgttatcaat gtggttgttt tctgccaatt tttcaactgt
    17581 tgtgttgtga gtttcagcga tttctgaaag tgtatcacct tctttaacag tgtaagttga
    17641 tgattcttga gcagatacaa atgatggagc aaatactgca aacaaggcag ctactcctgc
    17701 aagagttgct ttaatctttt tagttattga tttcatattc gaaaattctc cttctttcta
    17761 tagttctatc atacccttta aatattaccg tttcttgaca cttttatgta gaaatattac
    17821 aaaattattt tttatttccc taaataaggt gttttttgtc ataaaagata ctatttttat
    17881 gctatttgag gtattagaaa ggttttcatc cacaattaaa gccaagcccc tcattctttg
    17941 atataataga gataagaatt tttataaggg gaaactgatg aaatcacttc gttttcaatc
    18001 tgtctttgat atcatcggac cagttatgat tggcccatct agtagccata ccgctggtgc
    18061 tgttcgtatt gggaagattg tctcttccat ttttgatgat actccgacag aagttgaatt
    18121 ccaacttttt aactcatttg ccaagaccta tcgtggtcac ggaacagacc tagcccttgt
    18181 tgcaggtatt ttaggaatgg atacagatga tcctgaaatt ccaaatagtc tggaaattgc
    18241 ccacaagcgt ggtatcaaga ttgtctggac cattcagaaa gacagcaatg cccctcaccc
    18301 taacaccact aaaattactg ttaaaaatgc ccacaagacc atcagcgtga ctggtatttc
    18361 tatcggtgga ggaaatattc aggtaaccga actcaatggt tttgccgtct ctctcaatat
    18421 gaatacaccg actatcatca tcgttcatca agatattcca ggtatgattg cccttgttac
    18481 agaggcgctt tcccgctatg gtatcaatat cgcccagatg aatgtcactc gtgaaaaagc
    18541 tggtgaaaaa gccattatga ttatcgaagt tgacagtcgc aactgtgatg aggctatcga
    18601 agaaattcga aaaatccctc atctccacaa tgtcaatttc tttaaatagg aggaagcatg
    18661 ttttattcta tcaaagaatt ggtcgagcaa gcagatctgg actttcaagg aaatgtcgca
    18721 gaactcatga ttacaacaga gtttgaattg accggtcgcg aacgtgaaga agtcttcctt
    18781 ctcatggaac gcaatctgga agttatgaaa gcctctgtcc aacttggcct caatgaaaat
    18841 aaatctcgta gtggcctgac aggtggagat gctgccaaat tggatcacta catcgaaaac
    18901 ggaaaaactc tgtcagatta tacgattctc tcggctgccc gaaatgccat cgcagtcaat
    18961 gaacacaatg ccaaaatggg cttggtctgt gccactccaa ccgctggaag tgctggctgt
    19021 ctgccatccg ttctcactgc tgctattgaa aaattagacc tcagccacga gcaacaattg
    19081 gatttcctct ttgctgctgg tgcctttgga ctagtcatcg caaacaatgc ctccatctca
    19141 ggtgctgagg gtgggtgtca agctgaagtt ggttcagcct ctgctatgag tgctgccgcc
    19201 ttgactctgg ctgcaggtgg aacaccttat caggccagtc aagctattgc ctttgtcatt
    19261 aaaaatatgc taggcctcat ctgtgaccct gttgcaggtt tggtcgaagt tccctgtgtc
    19321 aaacgtaatg ccatgggagc tagctttgct ttcatcgcag cagacatggc cttggcaggt
    19381 atcgaatcta aaatccctgt ggatgaagtg atcgatgcca tgtaccaagt aggagcaagc
    19441 atgccaactg cctttcgtga aacagctgaa ggtggactcg ctaccacccc tactggtcgt
    19501 cgcctccaaa aagagatttt cggagaataa gcttatcaaa taggagaaac catgacctct
    19561 atcacagcga tttttttcga tttggatgga accctcgttg atagttctat cgggattcac
    19621 aatgccttta cctatacctt taaagagctg ggggtgccta gccctgatgc caaaactatt
    19681 cgtggtttta tgggaccacc tctcgaaagt agttttgcga cctgcctgtc caaagaccaa
    19741 atttctgaag ccatgcagat atatcgttct tactataagg caaaaggcat ctatgaagct
    19801 caactctttc ctcagattat agacttgctt gaggagttat cgagcagtta tccactctac
    19861 atcaccacga caaagaatac atctactgct caagacatgg ccaaaaactt ggaaatccat
    19921 catttctttg atggtattta tggttctagc cctgaagcac cccataaggc agatgtcatt
    19981 caccaagcct tacagacaca tcaactagca ccagaacaag ccatcatcat cggagatacc
    20041 aagtttgata tgctgggagc tcgagaaaca ggtattcaga aattggccgt cacttgggga
    20101 tttggagagc aagcagatct actaaactat caacctgatt atatcgctca caaaccctta
    20161 gaagttttgg cgtattttca atagcataga ctgggtaaca actccatttc agaagaaaat
    20221 gaagtaatac tcaatgaaaa tcaaagagca aactaggaaa ctagctgcgg gctgctcaaa
    20281 acactgtttt aagattgtag atggaactga cgaagtcagc tcaaaacact gttttaaggt
    20341 tgtggatgga actgacgaag tcagctcaaa acactgtttt gaggttgcag atagaactga
    20401 cgaagtcagc tcaaaacact gttttaaggt tgtagatgga actgacgaag tcagtaacca
    20461 tatacggcaa ggcgacgttg acgtgatttg aagagatttt cgaagagtat aagtctctac
    20521 ataataaaac gcatattacc aaggttgttt aacttgataa tatgcgtttt tcttttttat
    20581 tcaatgtggg ttgtttgatt agcaaaggcg ataatagctt gcttcaactc atctccactg
    20641 agagtgcgga actctccaat cttttgattg atggattcta aaggcatgac attaacctta
    20701 ccaacgaaaa tcttatccat aacttgattg tcaacgagtt cggttgatac caagagttct
    20761 tcgtagagtt tttcacctgg gcggattcca acttcaacga ttggaatttc actctcagtg
    20821 tggccactta gaagcaccat cttcttggcc aagtcataaa tcttgactgg tttgcccata
    20881 tcaaggataa agacttcccc atctttggca taagcaccag catggataac cagacgacta
    20941 gcttctggaa tggtcataaa gtaacgggtc atgcggaagt ctgtcaccgt tacaggccca
    21001 ccttcagcaa tctgacgttc aaagactgga atgacactac cacggctacc aagaacattc
    21061 ccaaaacgaa ctgcacagta ggttgattgg ctacgttggt taaagccagt gacaatcaac
    21121 tccgccacgc gcttggttgc tcccataaca tttggtggat taactgcctt atctgtcgaa
    21181 atcataacca tcttaggcac cttggcttca tcaacggctc tagcaacatt gtaagttcca
    21241 cggatattgt ttttgaaggc ttcttttgga ttgcgctcca tcataggaac atgcttgtgg
    21301 gctgccgcat gataaacaat agcaggtttg tactgctcaa agacttgcaa caaacgatca
    21361 tagtcttgaa tgtccgcaat cacaggtaca taatcaatcc cttggaactt acgaatcaat
    21421 tcatgataaa caaggtagat tgagttttcc ccatgaccga gcaagacaat gcgttcagga
    21481 ttgaagcgac taacttgacg acagatttca gaaccgattg aacctccagc tcctgtgact
    21541 aagatggtct tacctgtcag ttctgcaccc agacgcgatt cgtcaagacg gatttcctga
    21601 cgacccaaaa ggtccgtaat atcaattttt tggaagccag tacctgcttg gtgaaggccc
    21661 tgaacaacag tttcaacctt aggcatcttg taacatttga cacccagctt attacacatc
    21721 tgcaagatac gctcatattc tgacggatcc agcgacggaa tcgcaacgat gacacgctcg
    21781 atttgatggc gtttggctaa ttcaggcaga ttgtcataag agcccaaaac aggaatacca
    21841 ccaagttttt gacccttttt cttagaatcc ttatccaaaa taccgaccag ttctaattca
    21901 ctggttggat gttggtaact atccataaag agagccccac catcaccggc accaatcaag
    21961 aaggtccgac ggtgttctcc atcaccacta ccttttttgc gtctggagta gattaactgc
    22021 caagtaatcc gtggcaataa aatcaagaag gtactcaaca agataaagag aatgatgaaa
    22081 cggatggaga agagtggcaa gaaggcataa cagatactat atgacaagac actgctagca
    22141 gtcacaccaa aaaagatttt catgaaatcc gtaatcttgc tgtaacgact aatgctcgcg
    22201 ttcaaccccc aaaaaccaat catcaattga tagaacaaga aggccaaact cgtatagata
    22261 atgtagtcaa caggtgctgg attaatcagc ccataaaata aaatataaga tacaattatg
    22321 gaaaccacca tactgaaaat atcaaatatt ccccagaaaa cctgcttttg ttgtttattt
    22381 aaaatttcca ccagatcaat cacataatct gttagttttt tattcataga aatctactcc
    22441 tccttaaaag agttttacta tattgttatt atagcatatt ttgatttatt tggcttattt
    22501 tatccaaata aattattgtt cccttgtact ccttcttcca tttaaatcct ctaattaaac
    22561 ctacaatcgt cccaaggcca taagcaaagt gaatggaaaa taaaagaaag ggcatcacaa
    22621 ttagaaatcc atttttatgt tttaataaag tcagcaaagt gagtaatgac aaaagtagaa
    22681 aataggcacc taatagtaaa gttatgaata cgaatgtgat cggtaacaat gctagactaa
    22741 acacaagact caaaacaaat aaacaaggaa catagtgaaa taatgataaa cacttaaact
    22801 gaacatgact tgtcaagcca atccacaaac catttgaata cttttgatgc agcattttct
    22861 tgaatgttgg tcgaatatac tgataagata gaatacttgg gctatagcgg attttataac
    22921 catgttctcg aattctataa tgaatatcat tatcttcagt tcggccaagt tgctcattta
    22981 ctaaaccaac cttctggaaa acctctcgtt tatacatccc atgaaaaata gaagaaacat
    23041 atctatcctc ggaactattt cgataattgg caatgctact gccaaacata ttttcctcaa
    23101 caagatgcaa ggtctctgcc cattttcctt ttccttcgac aatcgtcggt ctaggccccc
    23161 cacagacaaa ttcaccttgt tgaataatag ccacattgtt aattacaaaa ctctcagtaa
    23221 cttttgaatg agcatcaatt tttaaaataa ggtcccctac agaatgttta actcccaggt
    23281 taaaaccact agcttgattt ttcttaggat tgttatacaa tctaattgag ttaaactctg
    23341 tatcttcctt tataaattgc tgaatgatag ctgtggtccc atctgtggac atagcattta
    23401 taaatagaat ttcaatatcc tctttaggat aggtttgatt ttttaagtct tcaattagac
    23461 caggcagata tttttcttca ttgtatgcac tgattacaat ggatacgaga agactttcaa
    23521 cattttgagt cactactact ctcctgaatt tttccttcca ccattctatc ataattttca
    23581 agactttccc atttttatct tgaaagccag aaaccttact tgacattata gtgaaaaagc
    23641 cttaaaataa gctgttatta aaatcagcta gaagaggtat tatatgaaaa agcaatcact
    23701 cttttttgtt ccaggtatta tcctgattgg tgtttccttg cgaactcctt ttactgtttt
    23761 acccattatt ttgggaaata tttcgcaagg tctggaggta gaagttagtt cgcttggtgt
    23821 cttgaccagc ctgcctctcc ttatgtttac cctcttttca ccattttcta cccaactggc
    23881 tcagaaaatc ggcttggagc atctcttcac ctacagcctc ttcttcttga ccatcggctc
    23941 acttattcga ctaatcaatc tgcccctgct ctatctagga accttgatgg ttggggcaag
    24001 tgtcgcagtc atcaatgtcc tgcttcctag tcttatccaa gccaatcaac caaagaaaat
    24061 tggttttctg accaccttat atgtaacgtc tatggggatt gcaacggctc tggcttccta
    24121 tctagctgtg cccattacac aagccagttc ttggaaagga cttatccttc tcctcacgtt
    24181 actctgtcta gcaacttttt tggtctggct cccaaatcac cgctataatc atagactagc
    24241 tccacaaacc aaacaaaaaa gtcaaataaa ggtcatgcgt aataaacagg tttgggcaat
    24301 tattatcttt tcaggttttc aatccttgat cttttacacc gtcatgacct ggttacctac
    24361 catgtctatc catgcaggtc tatccagtca cgaagctggc ttgctgactt ctatcttatc
    24421 tctgattagc attccttttt caatgaccat cccaagcctg acaaccagtt tatctactcg
    24481 caaccgtcag ctcatgctca ctctggtttc actagctggt gtggtcggca tttccatgct
    24541 ctttttccca atcaataatt tcatttactg gcttgccatc catctcctca tcggaaccgc
    24601 aaccagtgcc ctcttccctt atctcatggt caacttttca ctcaagacaa gcgcccctga
    24661 aaagacagcc caattgtccg gcctatctca aacaggaggc tatatcctag cagcctttgg
    24721 gccaaccctc tttggttaca gttttgacct gttccactct tgggtaccat ctgtagctgc
    24781 cctcttgctc atcgatatcc tgatgactgt ggccctcttt acagtggaca gagcggataa
    24841 gatcctttaa acttctagtt ttagctagaa gttttttata tataaaaatt ttacacattt
    24901 ctcttgacag ggctttcttt tagatgtaca atgtatgtgt agaaaaatta tatataaaaa
    24961 tcttacacat tagaaaagga ggtttcccat gtactttcca acatcctctg ccttgattga
    25021 atttctcatc ttggctgtac tggagcaggg tgattcttat ggttatgaga ttagccaaac
    25081 cattaagctg atcgctaata tcaaagaatc cacactctat cccattctca aaaaattgga
    25141 aggcaatagc tttctgacaa cctattctag agagttccaa ggtcgcatgc gcaaatacta
    25201 ctccttgaca aacggtggta tagagcagct cttgacccta aaagatgaat gggcactcta
    25261 tacagacacc atcaatggca tcatagaagg gagtatccgc catgacaaga actgaatacc
    25321 tgactcagct agaactctat ctcaagaaac tacctgaagc tgaccgtatc gaagccatgg
    25381 actatttcag agagctcttt gacgatgctg gagtcgaagg agaagaagaa ctcatcgcta
    25441 gtttgggaac tcccaaagaa gcggcccacg aagttctatc caatcttctc gataaaaaaa
    25501 tcaatgaagc acccgctcaa aaaaataacc gacaaatttt acatatcgcc ttgttagccc
    25561 tccttgcagc acctatcggc attcctctgg gaatcgccat cctcgtgacc ctgttcgcaa
    25621 ttcttgtagc cgctttgact gtcattctgg ctttctttgc agtttccata ctgggtatca
    25681 tcggcggatt cctattttta gttgaaagtt tcactgtcct cgcccaagcc aaatcagcct
    25741 ttatcttgat ttttggttct ggtttactgg ctatcggtgc ttcttcgcta gttttacttg
    25801 gcatttccta tgcaactcgc ttcttcggtc tactcattgt tcgtctggta caatttgttc
    25861 ttaaaaaagg aaagagaggt aatcagcatg cgtaaatgga caaaaggatt tctcatcttt
    25921 ggtgtggtga ctaccgttat cggctttatc ctgctttttg taggtatcca atctgacggg
    25981 attaagagcc tactttccat gtccaaagaa cctgtctatg atagccgtac ggaaaagcta
    26041 acctttggca aggaagtcga aaacctagaa attactctcc accaacacac gctcaccatc
    26101 acagactctt tcgatgatca aatccacatt tcttaccatc catctctttc tgctcaccat
    26161 gatcttatca ccaatcagaa cgatagaact ctgagtctca ctgataagaa actgtctgaa
    26221 actccgtttc tctcttctgg aattggtggg attcttcata tcgcaagtag ctactctagt
    26281 cgttttgaag aagttattct ccgactacca aaagggagaa ctctaaaagg gatcaacatc
    26341 tcagccaatc gcggacaaac caccatcata aatgctagcc ttgaaaatgc gaccctcaat
    26401 acaaacagct atatcctccg aattgaagga agtcgtatca aaaacagtaa actcacaacg
    26461 cccaatatcg ttaatatctt tgatacagtt cttacagata gtcagctaga gtcaacagag
    26521 aatcacttcc acgctgaaaa tatccaagtc catggcaagg ttgaactgac tgccaaagat
    26581 tatctcagaa tcatcctaga ccagaaagaa agccaacgaa ttaactggga catctcaagc
    26641 aactatggtt ctatcttcca attcacaaga gaaaagcctg aatcaagagg tacggaatta
    26701 agcaaccctt acaaaactga aaaaaccgat gtcaaggatc aactcattgc gagatctgat
    26761 gataatattg atctaatatc cacaccaagc agacgttgac aaaaacgctt acatttgcta
    26821 ctatggaaac atatttatct aactaaaaag gaggttctac catgaaacaa gaatggtttg
    26881 aaagtaatga ttttgtaaaa acaacaagca agaacaagcc tgaagagcaa gctcaagagg
    26941 ttgcagacaa ggctgaagaa acgatagcca atctcgatac accaattgga aaaaatactc
    27001 aagtagagga ggaagtctct caagctgaag tcgaactgga aagccagcaa gaagagaaaa
    27061 ttgaaactcc tgaaggcggt gaagcgagaa cagaaataga agaaaagaag gcatctaatt
    27121 ctactgaaga agagccagac ctttctaaag aaacagaaaa agtcactata gctgaagaga
    27181 gccaagaagc tcttcctcag caaaaagcaa ccacgaaaga gccacttctt atcagtaaat
    27241 ctttaaaaag tccttatatc cccgaccaag ctccaaaatc tagggataaa tggaaagagc
    27301 aagtgcttga tttttggtct tggctagtag aagcgatcaa atctcctaca agtaagttgg
    27361 aaacaagtat cacacacagt tacacagcct ttctcttgct cattctgttt tctgcatctt
    27421 cctttttctt tagtatctat cacatcaaac atgcttacta tggacatata gcaagcatta
    27481 acagtcgctt ccctgagcag ctagctcctt taactctttt ttctatcatc tctatcctag
    27541 tagcgacaac actcttcttc ttttcattcc tcttgggtag tttcgttgtg agacgattta
    27601 tccaccagga aaaggactgg acgctagaca aggttctcca acaatatagt caactcttgg
    27661 caattccaat cttcctcact gctattgcta gtttctttgc tttctttgat agcctacgat
    27721 ttacagctct cttgtgtgtg attagcattg gaatcattct gcttgccagt ctccatatca
    27781 ttacaagacc aagtcaagca agtgaaaccg actccttcta tcaattattc ttgtctgtcc
    27841 ttgtgaacgg agttattatc ctcctcttct ttgtagctga agtggcactg attggagatt
    27901 atcttcgtat cttggccttt ctttaaaatt caatcctgtc atccttggca ggattttttc
    27961 tatgtcaaaa aagcaagtcg attgacctgc ttctgcttta cttttcttgt gctaatgttt
    28021 taaaatcttt gtctaatatg ggttgcactt ctatttgatt ggcgtctagt tggtggtaaa
    28081 aagatggggg taatacctct aagaattttg catagtccaa gcgagctatg gattcatagt
    28141 cttctggttt agagccgtct cctgtgattt gaaccaagtc aatctcccac tggacttcct
    28201 tatccaccaa ttgctcaata taggctgcag gaacaaacgg ttctctcggt aaaactgtct
    28261 tgactccttg agctaaatgg taaacgccat gcacttttcc ttctccatcc tgatagaagg
    28321 aaactcttgc aaagtaggca tctgtctctt gaaccgcacg cacacgcgct tcaaactgag
    28381 ccaagccatc tgcctctaaa aagcttttca agttctcacg actaaagaaa ataggattaa
    28441 aaattccttg gcaaatcgta aaacgagcta cagggtctgc tagataggct tgaatacttg
    28501 cttggaaata agcttcaaaa tcaaaaccat ctagcccttc aatatcagtc cctgtataag
    28561 caagcaaagc atctaaaaat gacttgataa tctgccagtc tgtctttgtt agtaggtcag
    28621 gaagatcgac acggtaagcc ttttgaccat cagcataact gaccttaaag agaaattgtg
    28681 attgccccac tatcgcacac tcaatatact cgagacgatt aagaggctga cgaagataga
    28741 ctacatcata gctatgtgac tccaaaccgt ctagcaaggc caagatcgac ttggcattca
    28801 aaatctcttg ttctcctaaa atgctctgtt tatttggaat aaaaaatgtt tttgccataa
    28861 ctggactcct ttgaaatcgt ttacatacag tataccttat tttcctgaaa gatacaaaaa
    28921 caaactttag atttttgagt acaaagcata gaaaaacagc ccctgaggac tgtttgatct
    28981 tatacagtag ctgcctgatc caagctttca ccgatagcgg ctaggcgctc aatcacttca
    29041 gcttgtgtca attcattttt tgaaacatag cggttacgtg ggtgaacacg gcactcgtgt
    29101 gagcatccac gaaggtactt gtcttcattt tcttctgatg tcaagatacg acggttacag
    29161 aagggatttc cacagttgac ataacgttca catggtgttc catcaaacca gtctttccct
    29221 acgatggttg ggttgacatg gttgacatca acggcaatac gctcgtcaaa gacgtacatt
    29281 ttcccatccc aaagctcacc ttgaacttct gggtctttac cgtaagttgc gattcctccg
    29341 tgcaattggc cgacatcttt gtagccttca cggaccatcc agcctgagaa tttctcacag
    29401 cgaacgccac ctgtacagta aaccacgaca cgcttgtcca tgaatttttc cttgttatca
    29461 cggacccatt gtggtaactc acggaagttg cgaatatctg ggcgaatagc cccacggaaa
    29521 tgtcctaggt cgtactcata atcgttacgt gtgtcaagga caacggtatc tttatcaaga
    29581 agcgcttctt tgaactcttt tggagacaag taagcacctg ttgtttcaag tgggttgatg
    29641 tcattgtcaa agtcgttgtc ttccaaacca aggtggacaa tttctttctt gtagcgaaca
    29701 aacatcttct tgaaggcttg ttcattttct tcgtcaatct tgaaccagag ttcttccatt
    29761 cctggaaggc tgtgaacgta gtccatgtat ttttgagttg tttcatagtc acctgaaact
    29821 gttccgttaa ttccctcgtc agcgactagg atacggcctt taaggccgat tgatttacag
    29881 aaagccaagt ggtctgcagc aaattgctct gcattttcaa ttggagtata aaggtagtaa
    29941 agtaagacac gaatatcttt tgccataaga tttgttctct tttctattct taaattttct
    30001 aaatttttta tttatctaca ctagtatacc tgcttgagaa aacgaatgca atttatttga
    30061 ctggaaattg tagagggttc tcgaaatttc ctgaatggtt aaaataagga caagagaaaa
    30121 catggatatc tatatccttg tgccaaaaaa accactgccc tccccagacc aacctgagga
    30181 aagcggtgat tcttatttta ggagttagga atgaatacac gaaatcaatt tagctgatta
    30241 ttttttgttt ttcaagaatt catcgtattg tttttgcatt tcgttcaata ctttttcgta
    30301 ggcaccttca gatttcaatt tttccatcaa ttctggaatc gctttatctg ggtctacagt
    30361 accagtgttg atagctgtat caaattgttg cattgtgtta gcaatagctg agatttcaga
    30421 tttcacattg tcagtattga agataaatcc aagcgctgga gattctttag cttctgccaa
    30481 ttctttctta gaattttcga tttgttggtc tgtaacgttt tcgttgatgt aaaggatcca
    30541 gttgttacca gtgttccatc cacccatgtg agtgtttcct ttgtagccat caagaacgcg
    30601 aacacggttt tctttacctt caattttttc ccagttcttg ccttctggac cgtaaacaag
    30661 accgttcaaa agttctgggt tcgtattcaa gaggttcaag atttccattg atttttcttt
    30721 gttcttagag ttgtttgaga tgacaaagtt agcaacttgt gttgtttggt ttttcttgat
    30781 gaagttagtg attggtttga tttggatatc tttgttggca acacgtgaaa gcaagctgtt
    30841 accgtagtca gctggtccta ctgtttcttc acgaacgaac caagtatctt gttgaaggtc
    30901 aaatgaagtg tcacttgttg cgacgtcttt tggaatgtag ccagcttcat agaatttgtg
    30961 aagagtcttc aagtgttctt tgaaacgagg cacttcgtaa cggtttacaa ctttagtagt
    31021 atcgccttca aggtcaataa cgaatggaag cccgtttgct actgggtagt caaagttatc
    31081 agatgggatg aaaactttac caatagcaaa tggtactacg tctggagctt tttctttgat
    31141 ttgtttcaag actggctcaa gagtttcgta agaagtaaca cctgaaatat cgataccata
    31201 tttggcaagg agagttccgt tgaaggcaaa gttttgagat gatgctacgt tggctgcaac
    31261 tggtacagcg taaatcttac catttacagt attacccttg atataagctg gatcaagtgc
    31321 cttgtaaagg tctttacctt cttttttgta caattctgtc aagtcagcat aagcaccttt
    31381 ttgagcattt acaatatagt tatctgcaaa ggcgatatca tagttttcac cagatgatgt
    31441 gataactgac attttcttac catagtcacc ccagccaagg tattggatat ccaatttggc
    31501 accaactttt tcttcgatga ttttgttggc atttgctaac aattcatcca agttatctgg
    31561 tttgtcaccg atttggtaca ttttgataac aggtttgtca cctgaatcag cagctttttt
    31621 gctgttacct gtcaaatttc cacaagcagc aagacctgca gccaaagcga ctacactagc
    31681 agatgcaaaa gcatattttt tccagttttt catgataaaa actccttttt ttatttttaa
    31741 acttataaac aatgtaatga tcttaacttc acgcaaggga agtttggaaa caagtgctat
    31801 tctttcacac caccgatagt caaacctttt acaaagtagc gttggaagaa tggatacaaa
    31861 attgcgattg gaagggttgc taccacaacc atggccatac gacctgtttc tttcggtaga
    31921 gcaactccca gttgaccagt caagccgacc gctttggcaa tgtagtccat attttgttgg
    31981 atttgcatga gcaaatattg caatggatac aagttgtcac tcttgatgta aagaagggcg
    32041 ttgaaccagt cattccagaa accaagagct gtcaaaagcg tgatggttgc gatacctggt
    32101 agtgacaatg gcaaacagat ttggaagaaa atccgggcct cactggcacc atcgatacga
    32161 gccgattcga gaatggcttc tggaatggtc ttcttgaaga aggaacgcat caagatgata
    32221 ttgaatggtg agagaagcat tggaacaatc aaggcccaaa cagtgtcacc aagctgaagt
    32281 acacgggtca ccatgatata acctggtacc aaaccagcgt tgaacaacat actgagaagg
    32341 acgaagatgg taaaaaatct gcgatactta aaggttgtcc gtgaaatagc gtaggcatag
    32401 gttgttgtga taaagacatt tgtcaatgtc ccaactacgg ttacaaagac agagatgaag
    32461 agggcttgta ggattttatc cttaaactgt gccaaaaact caaaaccgtc taagccaaat
    32521 tgggatggga agaagctata gccgtattgg aggaggcttt tctcgtctgt cactgaaata
    32581 atgataacga atacaaaagg taggatacaa gagagggcaa tcaaacccga aatgatactg
    32641 aagaagatat ctgctttctt actgaaggag tgaatgccga cattatcaat tttttctttt
    32701 ttaattttct tttttgccat attctcctcc tttctagaac aaagctgagt ttggatcgac
    32761 tcgtcttgca agcaagtttg ataggataac cagaatcaaa ccaacaacgg attggtaaag
    32821 accggctgct gcagccatac cgatatctgc tgtctgagtc aaaccattaa aaacatatac
    32881 gtccaaaacg ttggttacat tgtaaagctg accagcattg tgtgggattt gatagaagag
    32941 accgaagtct gcgcggaaga tatttccgac tgcaaggatg gtcaatacag ttacaagcgg
    33001 agtcaactga ggaatggtta cgttgcgaat acgttgccac ttgctagctc cgtccactgt
    33061 cgctgcttcg tagtaggttg gatcaattcc catgatcgtc gcatagtaca tgacactgct
    33121 atatccaaaa cctttccaaa tacctaggaa aagtaggaga tagggccaga tgcccaggtc
    33181 agcgtagaaa ttgacttctt tgagaccaag actttccaat agatgattga acaccccttt
    33241 atcaatattt aggaaggcat ctgtaaagaa actgatgata acccaagaca agaagtaagg
    33301 gaacaacata gaagtttgga aaatcttcac cattctctta gaacggagct cgctgaggat
    33361 aatggcaatc cctacagata caactaaacc tagaaagata aagccaagat tgtagaggac
    33421 agtatttcgt gtgataataa aggcgtctct tgaactaaat aagaatctga aattatcgag
    33481 tccgacccat ttactattta tgatactatc tatgaaacca ttactggtca tgtggtagtc
    33541 tttgaaggca accacgttcc caaatactgg aatgtaaaag aatagaatca accagagtgc
    33601 ccctggcaaa accatcaaga gaaagatcca gttgtctctc aatgtttttg aaaacttttt
    33661 cataatttcc tcccttttta ttttgatatc catctaaaaa ttctttttta gacttttgat
    33721 aacgattaca ttattagtat actcctattt gcaggttagg ttaaactcct aattatagaa
    33781 aaaattccac aaattatgta gcagatttaa aactttatca ccactatcaa acaaatgtcc
    33841 taaatcaatt gtttatttta tctctattag cccagtgatg gcgtcactct gttataagca
    33901 tccaacaacg gggtatactg aaaaatctcc agactaggga actcagcgat agttcctaat
    33961 ctggagattt ttaatatgtt attaggcgtt tgctttcaac ttagcaataa cctctttaag
    34021 attatcaatc aactctgctt cagtatgctc agagcctttt tcatctgcca agaacaaaac
    34081 tgctttttga agttcttctt gagagttttc aaggacatcc ttatctgctg tttctttgcc
    34141 cgctgtttgt cctccatcct tagttgctga ctggctttcc ttaatggact ctagggaagc
    34201 aatggcatct ttgactgttt gcaagatatc acgtaaacct tgctctgtca aactatcatc
    34261 tgtaagagct ttcttagcct ctgccaaaac cagacgtgct gaatctgtgg taggattcga
    34321 tacacctgtc aatgatctca aaagattttc taaggtttga gtctgcttac taatactaga
    34381 ctaaaatcaa aaagcattac ataacagtga tatgaaatca actaaagaag aaatccaaac
    34441 catcaaaaca cttttaaaag actctcgtac agctaaatat cataaacgcc ttcaaatcgt
    34501 tctatagtaa aatgaaacaa gaacaggaca aatcgatcag gacagtcaaa tcgatttcta
    34561 acaatgtttt agaagtagag gtgtactatt ctagtttcaa tccattatat ttcgtctgat
    34621 gggcaaatct tataaagaga ttatagagct tttatagtga tttgaaataa gatgtgaaca
    34681 actctatcag gaaagtcaaa ttaatttata gaaatatttt agcagccaag gtgtactgtt
    34741 atagattcaa tacactatac ttggtggttt agctctcctg ttttctcttt tagctttaac
    34801 cagccataaa tggtattacg tgagatttgg aaaacgtgtg atgcttctgt tatactacct
    34861 gttcgctcac aataagagag aactttttta cgaaaatcta ttgaatattc cataaaagat
    34921 tataccacat tgtgtactat ttttggttca ttttactata tcactttgga ctatatcggt
    34981 ctagttatgt ctaaacgatt atagctggat actaagagaa atcaaaaaag cactaaggga
    35041 gaacgtccca aagtgcttag tttcaaggct ttacagccta tcttatttaa taaaatatta
    35101 caacattttg ttgtagaatt caacgacaag tgcttcgttg atttctgggt tgatttcgtc
    35161 gcgttctggc aagcgagtca atgaaccttc caatttttca gcgtcgaatg atacgaatgc
    35221 tggacgtcca agagtagctt ctactgcttc aaggattgct ggaactttca atgatttttc
    35281 acgaactgag atcacttgac ctggagttac gcggtatgat gggatatcaa cgcgtttccc
    35341 gtcaacaagg atgtgaccgt ggtttacaaa ttgacgagct tgacgacgag tagtcgcgag
    35401 accaagacgg taaacaacgt tatccaaacg acgttccaaa agaagcataa agttgaaacc
    35461 taggattccg cctttgattt ttgtagcttg tacaaacaag ttacggaatt gtttttcacc
    35521 tacaccgtaa gtgaaacgaa gtttttgttt ttcagccaat tgcaaaccgt attctgacaa
    35581 tttagaacgg ttgtttggtc cgtgttgtcc tggtacgtag ttacgacgtg ccaattcttt
    35641 acctgtacct gtaagtgaaa ggccaaggcg acgagcttgt ttccaagatg gtcctgtata
    35701 acgtgacata tgaatgtcct cctgatataa ataatatttc ggtggaaata gtcacttaga
    35761 aagccctgat tcgtgcagat gcccttcgcc taaacagcca aggttactta tcataagaca
    35821 cctgttgacg agcttcatgc tttcctgctg atatttcaca caaaattcat tctaccatga
    35881 atagctggat ttgtaaaggg gttttaggct ttattttcac taccagagag gttgagaacg
    35941 agagtaaagg tacttcctag accgtactgg ctgctgactg tgatttcccc acccaattga
    36001 tgggccaatt cacgcgcaat cgcaagtcct aatccatgac cacctgtctt catgttacgc
    36061 gaagtttcga cacgataaag gcgtttgaaa atattttcca aatcctctgg ggcaatgccc
    36121 tgcccttcat cggtcacact gattgaaagc tggcccttct ccagcttagc caccacttcc
    36181 agcttggttc ctggagcaga atatttaaaa gcgttatcga ccagattcac caagatacga
    36241 gaaagcttag cataatctcc ctcaatccgg gcagactctg ggattacctg caagtggaca
    36301 tctcttctct cctgctcaat caaaaactga aattcactca tgcactcaat taagagcttg
    36361 tccagaaaaa tactgtcttt actggtagtt tccacctgat ttctagctgt gtttagggtc
    36421 aaaaaattca actcctcaac cagtttattg agcctctccg tctggcgtcc aatggttgct
    36481 agataatgag cttgctccga ctccttgata atcccatcca aaatcccttc taccgtcgct
    36541 tggatcgaag tgataggagt cttaatatca tgcgacaact gagcaatcat caagcccttt
    36601 tctcgttcgc tttcttccaa ggaatcaaag cttacctgca aatcatggga catctcatta
    36661 aaagtttgcc ctaattgctg aaattctaca ggaccttgaa cctccaaatt tgaaggaaaa
    36721 tccttggccg ctacccgctt ggcatgctcc ttgagtttgc ccaacgacgt aaagactggc
    36781 aataggagaa agagactaat cccagcaccg acaaggctgg caacgatggt catcccaagc
    36841 aaaaagtaaa tctcgccttt cgcaatcagc attttttgaa cagcccaaaa aacaaccaaa
    36901 atggttaaga gggttgaaat aatatatcca accaaaatat aactttttag tttcatgttt
    36961 gtcctctcgg tttctctatc ttatatccca acccccaaac tgtcttaata gtgggcgttt
    37021 ggtcactact atattttgcc agctcctgtc gaagagcatg gatatgcaca ttcaaggtat
    37081 tggtgtcatc cacgtagtct tctttccaga tcttttcata gaggtctgtc ttggagaaaa
    37141 ctcgctctgg attgctagct aaaatccaca gcaattcaaa tgatttaaca gttaaatcca
    37201 gcatttcttc tcctatttga acttcatgac tactatgatt catttttaga ttgccaaggg
    37261 aaatcagctc tgtttcgccc ccacgatgaa ggcggcgcaa aatattgtgg acacgcaaaa
    37321 ctagctcacg tgggctaaaa ggcttagcaa taaaatcatc tgctcccaag ctcaggccgt
    37381 aaatcttgtc ctgctcactg gtcttagcag taataaatag gaaaggctgc tctggtgata
    37441 agtattgaac ctcactgatt aaatcataac catccatccg aggcatcatg acatctgtga
    37501 taatcaaatc aatcggtttt ttcttgaaca gctctagcgc ttccagtcca tcatgggcta
    37561 ccaagacctg ataacctgcc tgaattaagt atctctgatg aatatctgtg atttctacct
    37621 cgtcgtcaac gagtaaaatt gtctttccca tctgtctctc ctttgataaa aacagtgcta
    37681 tactgcttta agtataacac tatttttatt gttttacgat gattttaatc tgctattgaa
    37741 agaaagtcct gattgctgat tgagttgtta aactaatctt agtcagccca ctatccatca
    37801 tttatttcct tagctgatta gttttcttct tttttgtttt tcaaacctag accaccgagt
    37861 aaacctgcaa gcgcaagccc aaggaaacca atacttgcca ttgatgtttg agtctcacca
    37921 gtatttggta gcatagcttt atcctctgac atcatcgtat cagacatctt gttagcagaa
    37981 gcagccatat tttcacctgc catcgtgttg gtagaacttg tcatggtgtc agcaggcatg
    38041 ctatctgtag tacctgtagc atgattgtga ttcatcggag tcacgccaga accagagtta
    38101 gaaggtgata atgaaccatt tgctgtgtct gatgtttctt taacatttat cttaatagtg
    38161 acttttttag ttgctacgat gttgtccaag tctggtttac cgtctttgtt accatagaca
    38221 ttgactgtag c
//
LOCUS       DAVHLA010000015        36789 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVHLA010000015 DAVHLA010000000
VERSION     DAVHLA010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36789)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36789)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36789
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.015"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            6..95
                     /locus_tag="VVO77_000897"
     tRNA            6..95
                     /locus_tag="VVO77_000897"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:42..44,aa:Ser,seq:tga)
     gene            106..179
                     /locus_tag="VVO77_000898"
     tRNA            106..179
                     /locus_tag="VVO77_000898"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:140..142,aa:Met,seq:cat)
     gene            183..255
                     /locus_tag="VVO77_000899"
     tRNA            183..255
                     /locus_tag="VVO77_000899"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:216..218,aa:Phe,seq:gaa)
     gene            268..348
                     /locus_tag="VVO77_000900"
     tRNA            268..348
                     /locus_tag="VVO77_000900"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:302..304,aa:Tyr,seq:gta)
     gene            353..423
                     /locus_tag="VVO77_000901"
     tRNA            353..423
                     /locus_tag="VVO77_000901"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:385..387,aa:Trp,seq:cca)
     gene            438..510
                     /locus_tag="VVO77_000902"
     tRNA            438..510
                     /locus_tag="VVO77_000902"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:471..473,aa:His,seq:gtg)
     gene            521..592
                     /locus_tag="VVO77_000903"
     tRNA            521..592
                     /locus_tag="VVO77_000903"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:553..555,aa:Gln,seq:ttg)
     gene            602..685
                     /locus_tag="VVO77_000904"
     tRNA            602..685
                     /locus_tag="VVO77_000904"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:636..638,aa:Leu,seq:caa)
     gene            complement(796..1527)
                     /locus_tag="VVO77_000905"
     CDS             complement(796..1527)
                     /locus_tag="VVO77_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEU5692936.1"
                     /translation="MAKLYAISDIHGYLDEFRDALNKVNLNDKDNRLFLLGDYLDNGL
                     QSFQVISKIIELEEVYPNQIITLLGNHEEWFYDWLILDKPTASAFPETIKSFFSPEEL
                     NYIFKSNANNFETGVRNEIKNNIKFNPFINWFKKRYRDKRYYETDTQIFVHAGIDEEA
                     GMLWKELTSSKIFTNKFPITTGRFHKAIISGHIASWEVAKDRRYLGKIYYDSKSHYLI
                     DGDVTNSKTIPVLYYDTITQKYHFL"
     gene            complement(1520..1756)
                     /locus_tag="VVO77_000906"
     CDS             complement(1520..1756)
                     /locus_tag="VVO77_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001058278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HEU5692937.1"
                     /translation="MNNVVTTQISIQLSQELNSLLNAIVEENNTTKTDFIRQAVIEKI
                     EDMYDIKVADEAYKKWVECGKKATSHEEMMRRYG"
     gene            complement(1972..2409)
                     /locus_tag="VVO77_000907"
     CDS             complement(1972..2409)
                     /locus_tag="VVO77_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEU5692938.1"
                     /translation="MDTSQVIKAHEVAKKAHFGQIDRAGIDYIKHPETVASFVATDEE
                     KAVAYLHDVIEDTSLTLLDLKKEGFSKNIIEAVDILTKKKGQDYQSYLNLVKKNELAR
                     VVKLADLRHNSDLTRLPLITEKDLERNKKYSSAIRFLRAKKKS"
     gene            complement(2450..3583)
                     /locus_tag="VVO77_000908"
     CDS             complement(2450..3583)
                     /locus_tag="VVO77_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEU5692939.1"
                     /translation="MAIRKGKDGNWVVDISNGFDPITLKQRRLVRKGYKTKKEAIEAE
                     HYLRSVELKERFYGAKITIPILYELLKEEDSINHRKASYINTQDNNYNKHIKDYFSMV
                     DNVGKLTYEDIYQFREHLRQKVAKNSDKPLSTNTINKIMILLKKIFDVGLRKGYYSSN
                     PAKLIKKLPIEKTKMQFWTVKEFQKFLTLFEPEEYNIKLLFTVLFFTGLRLGEALALT
                     WQDIDFSSNTIHITKSVYVNKGVTHISTTKTKAETRRIVINKKLSQELQDWKKRQKHL
                     LEQFTNNSLTLQVFQNSPITITKNAIEKQYKKIIERDSTLKKIRIHDFRHSHASLLIN
                     QGEDYLVVKERLGHASITTTIDTYSHLYPSKQKDLADKLDDLL"
     gene            complement(3587..3790)
                     /locus_tag="VVO77_000909"
     CDS             complement(3587..3790)
                     /locus_tag="VVO77_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HEU5692940.1"
                     /translation="MIATVTKNDLIALGFFEGTSKRIIRQGKELLITRGFTVYQNKRI
                     GTIPATIATELLVFDVQNSTLKE"
     gene            complement(3804..4586)
                     /locus_tag="VVO77_000910"
     CDS             complement(3804..4586)
                     /locus_tag="VVO77_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="HEU5692941.1"
                     /translation="MTSYNKKIVRTSSYIEIWEYEKPIFSKGKSILDTNTENKEKAKR
                     RTFDELTPLEQEQRLERMKKTRLEAKWNLLRLVDCNFDDTTSFLTLTTKENISDRNHF
                     KDSLKTFIKRFNYHIFNTKKSKLKYIAVLERQKRKAWHSHILLFSVPYIPHKQLLELW
                     GHGAVWINKVDVDSKENRGRYVTKYFEKGIGQELLENFGKQAYFSSRNLKKPDEDKFY
                     TYEDFNYDSSVVLYETEYTSKVYKYGQYFDNHVKYKKIRLDE"
     gene            complement(4770..5543)
                     /locus_tag="VVO77_000911"
     CDS             complement(4770..5543)
                     /locus_tag="VVO77_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEU5692942.1"
                     /translation="MKTLLIGDLHLKSQLILPIVDKIIQTHNIKRIIFLGDYVDLHGQ
                     TNNIQLYAKDLTFLYSWKIDKEQNGIDVINLIGNHDAYYLLGEQAPFSIQNLEVFFAV
                     KELLQDLKLQIAYQLDDYLVSHAGFNLIFDPKEWHFNLYTKEYEEELDILAYTIGPMR
                     GGKALGGSPLWAHFRELELLPNQDFPKQIVGHTPKESIDISKNVIGIDTFSLYIDKDN
                     KYQFIGNGDLLVYDQGHLEIISTNWATDETLKQLSKPQI"
     gene            complement(5587..6357)
                     /locus_tag="VVO77_000912"
     CDS             complement(5587..6357)
                     /locus_tag="VVO77_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEU5692943.1"
                     /translation="MAIYYSVSDIHGHYNEFIKSLNKIDLSDKQSKLILLGDYIDYGS
                     QSFQVISKIIELEKIYPKQIITLFGNHEEWFYDWLILDNPTASAFPETIKSFFSTEEL
                     NYILKTNPNNFETGVRNEIRNNDKYIPFINWFQKRYEDSRYFETENQIFVHAGIDEEA
                     NNLWKDLTSPEIFTNKFPITTGRFYKDIISGHFASWEVAKDKSYLGKIYHDSKSHYFI
                     DGDVKNSKTIPVICYDTVKKSYQYSKNTSLLPKKFDRA"
     gene            complement(6376..6765)
                     /locus_tag="VVO77_000913"
     CDS             complement(6376..6765)
                     /locus_tag="VVO77_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001165436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692944.1"
                     /translation="MQIFTYNDFLKDKEIVTFEQAEIILDELIKSSNIYDPEFQAYWK
                     ELIEYSAKYAEMRGKWRILTKEEQDTLDDTRTNIHNRIRDNLISIRGLAQINNKDTSW
                     FDKFHNDRKRMGDFANYINYIYAVNSR"
     gene            complement(6803..7117)
                     /locus_tag="VVO77_000914"
     CDS             complement(6803..7117)
                     /locus_tag="VVO77_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692945.1"
                     /translation="MKLNDFLKPELLGNKFIAVKGYTEVLDRETNKPVALRLNVSIQD
                     EDSDFFMEMIQVKVNTLSPTASVQEMANNKTCPVTLKDLNVGQYNGNLWFSCSNVILI
                     TK"
     gene            complement(7207..8529)
                     /locus_tag="VVO77_000915"
     CDS             complement(7207..8529)
                     /locus_tag="VVO77_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HEU5692946.1"
                     /translation="MFKLRQSADLTRNNIISCYKLKIMHWLILSISACILFSTIVNIR
                     APTFVQILFIFLGGFIIYKIHLKIKIFRYDLEHYLIIRESLLYVLHTNRLYTTSKDGS
                     GYEKIVRSAVLEYEIDRQKGHVLIKALITGDEFSKKVQSLDDVLSDVLELELEEKIIR
                     PSFIEYHFYYIKPKRLVLQSHSQRQEIDSLDIDLGYGVNYNPVKCSHILVSGGTGSGK
                     SVLISVLILEFLKRQSTVYIADPKNSDLGSLSHYFGNKYVATTPNNIARIVRVVVEEM
                     QERYQVMRDNFQYGSNFTNHGFKPVWLIFDEMGAFQATGSDKKSREIITEVMDGIKQI
                     ILLGRQSGIFILVSAQQVNASTTLSTELRDNLGLRIALGANSSEGYHMVFGSATPDKL
                     KPIEEKGSGYLYIQGSGKESAQYWESPYLDTTQFDFIKELQLYVTKSK"
     gene            complement(8535..8753)
                     /locus_tag="VVO77_000916"
     CDS             complement(8535..8753)
                     /locus_tag="VVO77_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001282606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692947.1"
                     /translation="MSDNLKAYLFLLGFVILAGIAIFIFPQGHFFSNSILILGCIPLL
                     ISTYYFAKIKLLGFYELLKELLDKIKGI"
     gene            complement(8793..9548)
                     /locus_tag="VVO77_000917"
     CDS             complement(8793..9548)
                     /locus_tag="VVO77_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEU5692948.1"
                     /translation="MIQLTASTWNINLRSRKGKQIPEMIAQELAQQNSDIICLTEYVK
                     TDNHSQFCSSLQTNGYTIFEDVRTIDFGNEILIAIKSDLVNDCQVITIDNDDNNPNFL
                     HVRVTIEGQELNIIGVRIKIGGENVFEDFKHRKTQLDKLIFNLPIHENTIILGDFNNG
                     FFKQNDDTHSYQGKPREFYSYPLLKSEMNKAGLTVHTPSEENSWKYCKLDHIIGNIPI
                     SNVCYSWRFLENPDYQNKVGFPDHAILSATISL"
     gene            complement(9976..10479)
                     /locus_tag="VVO77_000918"
     CDS             complement(9976..10479)
                     /locus_tag="VVO77_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692949.1"
                     /translation="MTQFQVRISGEAAYYLRMLKEKYETSEGINITKATILTRAFQNS
                     KTVTNWTKVVQDNSISLKNIYPVEEKELKLNVALSDEVAEGIKKYKEILPSATNTQSV
                     TLGVCVKFLLKAELMTQLNHDISEPEKDFDKKFSILEKQLLEIVAPVNHKLLSDTIWN
                     FKNNFIK"
     gene            10908..12185
                     /locus_tag="VVO77_000919"
     CDS             10908..12185
                     /locus_tag="VVO77_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HEU5692950.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKIDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFSLNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            12261..13745
                     /locus_tag="VVO77_000920"
     CDS             12261..13745
                     /locus_tag="VVO77_000920"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEU5692951.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGETVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNMQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVYELDS
                     YIEDPHTAVASAVYRKYQAVTDDATKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLETAPVRHKTTVAAADMQVAVEAYLGL"
     gene            13806..15086
                     /locus_tag="VVO77_000921"
     CDS             13806..15086
                     /locus_tag="VVO77_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEU5692952.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            15090..15710
                     /locus_tag="VVO77_000922"
     CDS             15090..15710
                     /locus_tag="VVO77_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU5692953.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQNLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLDPEKTY
                     YIGDRTLDVEFAKNSGIQSINFLESSFEGNHRIQALADISRIFETK"
     gene            15876..17054
                     /locus_tag="VVO77_000923"
     CDS             15876..17054
                     /locus_tag="VVO77_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEU5692954.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASNSEVAETV
                     TAAEEVAPSTGTSVPEEQTAETTRPVEEVAPQATTLAEKQETQVSSQTESAVEATTMP
                     VEEKATETTATSSEAKEVASSNGATAAVSTYQPEETKTISTTYEAPAAPDYAGLAVAK
                     SENAGLQPQTAAFKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPESSELGDKIA
                     EYAIQNMASRGISYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG
                     "
     gene            17567..17905
                     /locus_tag="VVO77_000924"
     CDS             17567..17905
                     /locus_tag="VVO77_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEU5692955.1"
                     /translation="MTRYQILLFLLEHSLCNQMAVQERLKIDQAALTRNFKILETEGL
                     VERHRNPENQREVLVEAAKYAKEQLVVNPPLQHIKVKEEMESILTEFERTELSRLLNK
                     LVLGIENIEI"
     gene            17916..18284
                     /locus_tag="VVO77_000925"
     CDS             17916..18284
                     /locus_tag="VVO77_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HEU5692956.1"
                     /translation="MSIITIILTTIVAWEHFYIFYLESIATQSDATSRVFNMEREELA
                     HPSVSLLFKNQGIYKALLGVCLLYGIYFSQNLEIVTIFVLFVIGAATYGSLTADKKII
                     LKQGGSAILALISILLFKYT"
     gene            18413..19009
                     /locus_tag="VVO77_000926"
     CDS             18413..19009
                     /locus_tag="VVO77_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001834193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEU5692957.1"
                     /translation="MSPFEAIKGLPAEIHGAEVRWLEVPTVFHKSAQVLEEEMNRYQP
                     DFVLCIGQAGGRTSLTPERVAINQDDARTSDNEDNQPIDRPIRPDGASAYFSSLPIKA
                     MVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKFPYVKAGFMHIPYMMEQVVNR
                     PTTPAMSLVDIRRGIEAAIGAMIEHGDQELKLVGGETH"
     gene            complement(19037..19894)
                     /locus_tag="VVO77_000927"
     CDS             complement(19037..19894)
                     /locus_tag="VVO77_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEU5692958.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSSFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQRFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            20024..21166
                     /gene="tgt"
                     /locus_tag="VVO77_000928"
     CDS             20024..21166
                     /gene="tgt"
                     /locus_tag="VVO77_000928"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEU5692959.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMLLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFRKYFVEKYGYNKSGRNF"
     gene            21267..23084
                     /locus_tag="VVO77_000929"
     CDS             21267..23084
                     /locus_tag="VVO77_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEU5692960.1"
                     /translation="MRIKWFSLVRITGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNHEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     ASVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAVAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPIVQTLRPLPYIHAILAAGTGILTIIVCTVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            23237..24388
                     /gene="nagA"
                     /locus_tag="VVO77_000930"
     CDS             23237..24388
                     /gene="nagA"
                     /locus_tag="VVO77_000930"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEU5692961.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            24551..25609
                     /locus_tag="VVO77_000931"
     CDS             24551..25609
                     /locus_tag="VVO77_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEU5692962.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            25760..26125
                     /locus_tag="VVO77_000932"
     CDS             25760..26125
                     /locus_tag="VVO77_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEU5692963.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            26201..27142
                     /locus_tag="VVO77_000933"
     CDS             26201..27142
                     /locus_tag="VVO77_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HEU5692964.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDIETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            27090..28106
                     /locus_tag="VVO77_000934"
     CDS             27090..28106
                     /locus_tag="VVO77_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEU5692965.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            28108..28434
                     /gene="comGC"
                     /locus_tag="VVO77_000935"
     CDS             28108..28434
                     /gene="comGC"
                     /locus_tag="VVO77_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HEU5692966.1"
                     /translation="MKKMMTFLKKAKVKAFTLIEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQADGRITEEQVKAYNEYYTKNGGA
                     NRKVND"
     gene            28427..28831
                     /locus_tag="VVO77_000936"
     CDS             28427..28831
                     /locus_tag="VVO77_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEU5692967.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQTLSNGSQKLTVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            28836..29096
                     /locus_tag="VVO77_000937"
     CDS             28836..29096
                     /locus_tag="VVO77_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692968.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVNINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            29059..29520
                     /locus_tag="VVO77_000938"
     CDS             29059..29520
                     /locus_tag="VVO77_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEU5692969.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            29498..29944
                     /locus_tag="VVO77_000939"
     CDS             29498..29944
                     /locus_tag="VVO77_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEU5692970.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQIAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKAEKKNQKRSLKRKRIPSQFNYNALNPE"
     gene            30047..30641
                     /locus_tag="VVO77_000940"
                     /pseudo
     CDS             30047..30641
                     /locus_tag="VVO77_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
     gene            30702..31655
                     /locus_tag="VVO77_000941"
     CDS             30702..31655
                     /locus_tag="VVO77_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU5692971.1"
                     /translation="MDFEKIEQAYIYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFTEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGF
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKVWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            31706..32896
                     /locus_tag="VVO77_000942"
     CDS             31706..32896
                     /locus_tag="VVO77_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEU5692972.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADVIVFTAGVGE
                     NAESFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            33045..33416
                     /gene="rnpA"
                     /locus_tag="VVO77_000943"
     CDS             33045..33416
                     /gene="rnpA"
                     /locus_tag="VVO77_000943"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEU5692973.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            33391..34215
                     /locus_tag="VVO77_000944"
     CDS             33391..34215
                     /locus_tag="VVO77_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEU5692974.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            34234..35220
                     /locus_tag="VVO77_000945"
     CDS             34234..35220
                     /locus_tag="VVO77_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEU5692975.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QAESQELEDLGLKVETNFDIEQVATEVMAYVQTIIDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNCYSRTFYITINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            35271..35894
                     /locus_tag="VVO77_000946"
     CDS             35271..35894
                     /locus_tag="VVO77_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEU5692976.1"
                     /translation="MLNKIRDYLDFAGLQYRNPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            36025..>36789
                     /locus_tag="VVO77_000947"
     CDS             36025..>36789
                     /locus_tag="VVO77_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="phosphoenolpyruvate-dependent sugar
                     phosphotransferase system; functions with enzymes IIB
                     (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for
                     anaerobic utilization and uptake of L-ascorbate; sgaTBA
                     are regulated by yifQ as well as Crp and Fnr; IIB is
                     phosphorylated by IIA and then transfers the phosphoryl
                     group to the sugar; IIC forms the translocation channel;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU5692977.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILL"
BASE COUNT        11102 a         6355 c         7720 g        11612 t
ORIGIN      
        1 attttggagg attacccaag tccggctgaa gggaacggtc ttgaaaaccg tcaggcgtgt
       61 aaaagcgtgc gtgggttcga atcccacatc ctccttttat attaacgcgg gatggagcag
      121 ctaggtagct cgtcgggctc ataacccgaa ggtcgtaggt tcaaatcctg ctcccgcaat
      181 aaggctcggt agctcagttg gtagagcaat ggattgaagc tccatgtgtc ggcggttcga
      241 ttccgtctcg cgccatttat atattttgga agggtagcga agaggctaaa cgcggcggac
      301 tgtaaatccg ctccttcggg ttcgggggtt cgaatccctc cccttccatt ttacgggcat
      361 agtttaaagg tagaactaag gtctccaaaa ccttcagtgt gggttcaatt cctactgccc
      421 gtgttaatag aattatggcg ggtgtggtga agtggttaac acaccagatt gtggctctgg
      481 catgcgtggg ttcgatcccc atcactcgcc tattttatat tggggtatag ccaagcggta
      541 aggcaaggga ctttgactcc ctcatgcgtt ggttcgaatc cagctacccc agttactatt
      601 tgccggcgtg gcggaattgg cagacgcgct ggactcaaaa tccagtgtcc gcaaggacgt
      661 gccggttcga ccccggccgc cggtatagta ttaaagacaa ggttttagga ccttgtcttt
      721 ttgttatgtc ataagaaatt tcttggaatt gttactaata attactaatt tcatataaaa
      781 gcacatgatt aaaagttata gaaagtgata tttttgggta attgtatcat agtaaagaac
      841 aggtattgtt ttgctattcg ttacatctcc atcaattaag taatgacttt tactatcata
      901 gtaaatctta cctaggtatc ttctatcttt agctacttcc caagaagcaa tatggcccga
      961 aataatagct ttatgaaatc taccagtggt aattggaaat ttgtttgtaa atatctttga
     1021 actcgttagt tctttccaaa gcattcctgc ttcttcatca atgcctgcat gaacaaaaat
     1081 ttgggtatca gtttcataat agcgtttatc cctatatcgc tttttaaacc agtttataaa
     1141 tgggttgaat ttgatattat ttttaatttc atttctaaca cctgtttcaa agttgttagc
     1201 attcgattta aaaatatagt tcaattcctc tggagagaag aagcttttta ttgtttctgg
     1261 aaatgctgaa gcagtaggtt tatctaaaat caaccaatca taaaaccatt cttcatgatt
     1321 ccctagaaga gtaataattt gattaggata aacctcctca agttcgatta ttttggaaat
     1381 gacttgaaaa gattgaagtc cattatcaag ataatctcct agtaaaaata ggcgattatc
     1441 tttatcgttt aaatttactt tattgagagc gtctctgaat tcatccaagt atccatgtat
     1501 atcagatatt gcgtataatt tagccatagc gtctcatcat ttcttcatgt gaggtagctt
     1561 ttttgccaca ttcaacccat tttttataag cttcatcagc gaccttaata tcatacatat
     1621 cttcaatttt ctctataaca gcttgtctaa taaagtcagt ctttgttgta ttattttctt
     1681 caacaatagc atttaataaa gaatttaact cttgactaag ttgaatagaa atttgtgtag
     1741 taacaacatt attcatataa cagccaccta atagttattt tagatacatt atactcctag
     1801 tctaaaagtt tctcaataaa aaatttcact ttttatagtt atttatttta ataaaattgt
     1861 agtatctgca aggatgtgcc agttcgagac cgaccgccag tatagtaata aagacaaagt
     1921 ttataagcct tgtcttttgt tttctcttta taaaatttta tagtttagtt actaactttt
     1981 tttctttgct cttaaaaatc taatagcaga actgtatttc ttatttctct ctaagtcttt
     2041 ttcagtaatt aatggtagtc ttgttaaatc tgaattatgc cgtaaatccg ccaactttac
     2101 aactctagcg agttcatttt tctttactag attgagataa gattgataat cttgtccttt
     2161 tttctttgtg agtatatcga cggcttctat aatgtttttt gaaaaacctt ccttttttag
     2221 gtctagtagg gttagtgaag tatcttcaat tacatcatgt agataggcga cagctttctc
     2281 ttcatcagtt gcgacaaaac tagctactgt ttcagggtgt ttaatgtagt caattcctgc
     2341 tctatcaatt tgtccaaagt gtgctttttt agctacttca tgtgctttta ttacttgtga
     2401 tgtatccatg atttaattat aaactttcca tttataaaac tcaattactt tatagtaaat
     2461 catctagttt atcagctaaa tccttttgct tacttgggta caagtgagag taggtatcaa
     2521 tcgtggttgt tatagaagca tgtcctagtc gctcttttac aactagataa tcttcccctt
     2581 ggttaatcag cagggaagcg tgtgagtgcc taaaatcgtg tatgcgtatc ttttttagtg
     2641 tgctatcacg ttcaatgatt ttcttgtact gcttttcaat agcatttttt gtaattgtga
     2701 taggactatt ttgaaacact tgtaatgtta ggctattgtt ggtaaattgc tctaatagat
     2761 gtttttgtcg ctttttccaa tcttgtaatt cttggcttaa ttttttattg ataacaattc
     2821 ttcttgtttc tgctttagtt tttgttgtgc tgatatgagt tactccttta ttaacataga
     2881 cagacttcgt gatatgaatt gtattacttg aaaagtcgat gtcttgccat gttagggcaa
     2941 gagcttcccc aagtcttaat cctgtaaaga atagaacagt aaagagtagt ttgatattgt
     3001 attcttcggg ttcaaatagt gtcaaaaact tctgaaattc tttgactgtc caaaattgca
     3061 tttttgtttt ttcaattggc aactttttta ttaattttgc tggattggag gagtaatagc
     3121 cttttcgcaa accaacatca aaaatttttt tgagtaaaat catgattttg ttaatagtat
     3181 ttgtgcttaa cggtttatca gaatttttag ctactttttg cctaagatgt tctctaaatt
     3241 ggtagatgtc ttcataggtt agttttccga cattatcgac catagaaaaa taatctttga
     3301 tgtgtttgtt gtaattatta tcttgtgtat tgatatagct tgcttttcga tgatttatac
     3361 tatcttcctc cttaagtagt tcatatagta tggggatagt tattttagct ccataaaagc
     3421 gttcttttaa ctctacactt cgtaagtagt gttctgcttc aatagcttct tttttcgtct
     3481 tatagccctt tctgacaagt ctacgttgct ttagtgttat tgggtcaaaa ccgttgctaa
     3541 tatcaactac ccaattaccg tctttacctt ttctaattgc catattttac tccttgaggg
     3601 tactgttttg aacatcaaaa acgagtaatt cggtagcaat agtagcaggt atagtaccaa
     3661 ttcgcttgtt ctgatagact gtaaagcctc gggttatcag tagctctttc ccttggcgga
     3721 taatacgttt agatgttccc tcaaagaaac cgagggcaat taggtcattc ttagtaacag
     3781 ttgctatcat gtgacttact cctttattca tctagtctta ttttcttgta ctttacatga
     3841 ttatcgaaat actgaccgta tttatagacc ttactagtgt attccgtttc atatagcacg
     3901 actgaactat catagttaaa atcttcataa gtgtaaaatt tatcttcatc aggctttttc
     3961 aagttgcgtg atgaaaaata ggcttgcttt ccgaagtttt ccaacaattc ttgtccaata
     4021 cctttttcaa aatactttgt gacatatcga ccgcgatttt ctttgctgtc gacgtcaact
     4081 ttatttatcc atactgcacc atgcccccaa agttctaata attgcttatg tggaatatag
     4141 ggaacactga atagcaaaat atgactatgc catgctttac gtttttgcct ctctaatact
     4201 gctatatatt ttaatttact tttcttggta ttaaaaatgt ggtagttaaa gcgtttaata
     4261 aatgttttga gtgagtcttt gaagtggttt ctatcgctga tattttcctt agtggtcagt
     4321 gtaagaaaag aagttgtatc atcaaaatta caatcaacta gacggagtaa gttccacttg
     4381 gcttctaagc gagtcttctt catacgttca agacgttgtt cttgttctag gggtgttagt
     4441 tcatcaaatg ttctgcgttt tgctttttcc ttgttttcag tattagtatc taaaatagat
     4501 tttccttttg aaaatattgg cttttcatat tcccaaattt caatatagga agaagtgcgg
     4561 actatttttt tattatatga ggtcataaaa aatagttcct tttaggttgg ctttcgccaa
     4621 aagattgtct atataataaa taaactagga ggagcaaagc tcctccacac ttctatcatg
     4681 tgtttctaag catcgctccg ctaaacacgc ttccagcttg ctgacctcca gtcagcagtt
     4741 tcgcttagtc acatgatgag aagtagtagt taaatttgtg gtttagataa ttgttttaat
     4801 gtttcgtctg tagcccagtt ggttgaaatg atttcaagat ggccttggtc atagactagc
     4861 aaatctccgt taccaataaa ttgatattta ttatctttgt caatatataa tgaaaaagta
     4921 tctataccaa taacattttt agaaatatca atagattctt taggggtatg tccaacaatt
     4981 tgtttaggaa agtcttggtt gggaagcaat tctaattctc taaaatgtgc ccataaagga
     5041 gaacccccaa gagctttccc accacgcatt ggtcctattg tataagctag gatatctaat
     5101 tcttcttcat actctttggt ataaaggtta aaatgccatt cttttgggtc aaatatcaga
     5161 ttgaaaccag cgtgactgac taaataatca tctagttgat aagctatttg taatttcaaa
     5221 tcctgcaaca attcttttac tgcgaaaaac acttctaaat tttgaattga gaaaggagct
     5281 tgttctccca gtaaataata agcatcatga ttacctataa gattaattac atctattccg
     5341 ttttgctctt tatctatttt ccaagagtat aaaaaagtga ggtctttggc ataaagttgg
     5401 atattgttag tttgaccatg taaatcaaca taatcaccaa gaaaaatgat tctcttaatg
     5461 ttatgtgttt ggataatttt gtcaacaatg ggtaaaatta gttgagattt taaatgtaag
     5521 tcaccaatta ataatgtctt catatatatt cccctcttta tttttgatat tagtctaaga
     5581 atagaattaa gctctatcaa attttttagg caatagagaa gtgttttttg aatattgata
     5641 ggatttttta actgtatcat agcagataac aggtattgtt ttgctatttt ttacatctcc
     5701 atcaataaag taatgacttt tactatcatg gtaaatctta cctaggtaac ttttatcttt
     5761 agctacttcc caagaagcaa aatgcccaga gataatatct ttataaaatc taccagttgt
     5821 aataggaaat ttgttggtaa atatctctgg actcgttagg tctttccaaa gattattagc
     5881 ttcttcatca atgccagcat ggacaaaaat ttgattttct gtttcaaaat aacgactatc
     5941 ttcatatcgt ttttggaacc agtttataaa tggaatatac ttatcattat ttctaatttc
     6001 gtttctaaca cctgtttcaa agttgttagg atttgttttt aaaatatagt tcaattcctc
     6061 tgtagagaag aaactcttta ttgtttctgg aaacgcagaa gcagtaggat tatctaaaat
     6121 caaccaatca taaaaccatt cttcatgatt tccaaaaagt gtaataattt gttttggata
     6181 aatcttttca agttcaatta ttttagaaat gacttgaaaa gattgagaac cgtaatcaat
     6241 atagtctcca agtaagataa gtttactttg tttatcagat aaatctattt tattgagaga
     6301 tttaataaac tcattgtagt gcccatgtat atcagatacg gaataataaa ttgccatata
     6361 agattctttc tataatcaac gtgaatttac agcgtatatg taatttatat aattagcaaa
     6421 atcacccata cgttttctat cgttatgaaa cttatcgaac caagaggtat ctttgttatt
     6481 gatttgagcc aagcctctaa tagatataag gttatctcta attctattat gaatattagt
     6541 tcttgtatca tcaagtgtat cttgctcttc ttttgtaagt attcgccatt ttcctctcat
     6601 ttcagcatac ttcgcactgt actcgataag ttctttccag tatgcttgaa attcagggtc
     6661 ataaatgttt gatgatttta taagttcatc taaaattatt tcagcttgtt caaaagttac
     6721 gatttctttg tcttttagaa aatcgttata agtaaaaatt tgcatagtaa gctcctttaa
     6781 tttttgaaat aattataaca cattatttag taattagaat tacattagaa caagaaaacc
     6841 ataaatttcc attgtattga cctacgttta aatcttttag agtaacagga caggttttat
     6901 tatttgccat ttcttgaaca gaagcagtag gggataatgt atttactttg acttgtatca
     6961 tctccataaa gaaatcagaa tcctcatctt gaattgacac gttaagtcgt aaagctacgg
     7021 gcttattagt ctctctgtct aatacttctg tatagccttt tactgctata aatttgttgc
     7081 caagcagttc tggctttaaa aaatcattta gcttcatgtg tacctctttt ctatcatcgc
     7141 agagcgatga ggaacagata tttttgctga aaatctatta aatttaagca aaaatatctg
     7201 ttgaaattat tttgactttg ttacgtataa ttgtagttct tttataaaat cgaattgagt
     7261 tgtatcaaga taagggcttt cccagtattg ggcagattct ttaccagagc cttgtatata
     7321 aagatagcct gaaccttttt cttcaatagg ttttaactta tcaggagtag ccgaaccaaa
     7381 gaccatgtga tagccttcac tagaattagc accaagagca attctcaatc ctaaattatc
     7441 tctgagttca gtacttaaag tagtactagc atttacttgt tgggcagaca ctaggataaa
     7501 aatgcctgac tgtcttccaa gtagaatgat ttgtttaatc ccatccataa cttcagtgat
     7561 aatctctctt gattttttat ctgaacctgt agcttgaaat gctcccattt catcaaatat
     7621 aagccatact ggcttaaatc catggttagt aaaatttgaa ccatactgaa agttatcacg
     7681 catgacttga tatcgttcct gcatttcctc aactacgact ctcacaatgc gagctatatt
     7741 atttggggtg gttgctacgt atttatttcc aaagtaatga gacaagctac ctaggtcaga
     7801 gttcttaggg tcagctatat aaactgttga ttgacgtttt agaaattcta aaatcaaaac
     7861 agatataagc acggatttcc cacttccagt tccacccgat actaaaatat gtgagcattt
     7921 gacaggatta taatttacac catatcctaa atctatatca aggctatcta tctcttgtct
     7981 ttggctgtga gattgtagaa ctaacctttt tggttttatg taatagaaat gatattctat
     8041 aaaactaggt cgaataatct tttcctcaag ctctagttca agcacgtcag aaagtacatc
     8101 atcaagagat tgaacttttt tactaaattc atcgcccgtt ataagagctt tgataagaac
     8161 atgacctttt tgtctatcta tctcgtattc taatactgca cttctaacga ttttttcata
     8221 gcctgaacca tctttagatg tggtataaag tctgtttgtg tggagtacat aaagtaagct
     8281 ctcacgtata ataaggtaat gctctaagtc atatcgaaaa atttttattt tcagatgaat
     8341 tttatagata ataaatccac ctaaaaatat gaagagaatt tgaacaaaag ttggagccct
     8401 aatattaaca atagtggaaa atagaatgca ggcagagata cttagtatca gccagtgcat
     8461 tatttttaac ttataacagg aaattatatt gtttcttgtt aaatcagcac tttgtcttaa
     8521 tttaaacata ttagttagat accttttatt ttatctaaaa gctcttttaa aagttcgtaa
     8581 aaccctaaga gcttgatttt tgcgaaataa tatgttgaga taagtagtgg aatacaccca
     8641 aggataagga tagaattcga aaagaaatgt ccttgaggga atataaaaat tgctatgcca
     8701 gctaatatca caaatcctaa aagaaataga tatgctttta aattatcact catttcatta
     8761 cctcctctaa taagcaatta ttttaaggaa aactataaag atatagtcgc cgataaaata
     8821 gcgtggtcgg ggaaaccgac tttattttga taatcaggat tttctaagaa tctccaagaa
     8881 taacacacat tagaaatagg aatgtttcct ataatatggt ctaatttaca atatttccaa
     8941 gagttctcct cagacggagt atgtacagtt aaacctgctt tattcatttc tgattttagt
     9001 aatggatagg agtaaaattc tctaggttta ccttgatagg aatgagtatc atcattctgc
     9061 ttgaaaaagc cattattaaa gtcacctaga ataattgtgt tttcatgaat tggtaaattg
     9121 aagattagct tgtctagttg tgtttttctg tgtttgaaat cttcaaaaac attttcccct
     9181 cctatcttga tacgaactcc aataatgttt aattcttgtc cttcaattgt cactctaacg
     9241 tgtaaaaagt ttggattatt atcatcatta tcgatagtaa tgacttggca atcattaact
     9301 aaatcactct ttattgcaat aagaatttca tttccaaaat ctatagtacg cacatcttca
     9361 aagattgtat aaccattagt ttgaaggcta gaacagaatt gagaatgatt atctgttttt
     9421 acatactctg tcagacagat aatatctgaa ttttgctgag ctagttcctg cgcaatcatt
     9481 tcaggaattt gttttccttt tcttgaacgt agatttatat tccaagtgga tgctgtaagt
     9541 tgtatcataa aatttcctcc taaaagttag tccgcaggag gaggcacctc ctcctgctat
     9601 ccttcgaatc catcaaagat ttctcctagt tcgtcttcat catagtagct ttccaattcc
     9661 tcatagaagt aatctaaggc ttcttggtca aaaaagttca ttgctattcc tcctctcagt
     9721 atttttttgt acattttaat tgtacaaaat taaaagaaga aagtcaacaa aaaagtatac
     9781 tttaatttcc aaaatgtaca aatttaataa aaaaagaatg agtctgggac aaaaagattt
     9841 tgattttagg aattctttat tataaatttt aaaaatcgat agattataca aaaaagcgaa
     9901 caagacagaa ttctgagtat cagataactc gttttgttcg ctttttatat ttaagattag
     9961 acttttgttc cagactcatt ttataaaatt atttttgaaa ttccatatgg tatcagaaag
    10021 taatttgtgg ttgactggtg caacgatttc aagaagctgt ttttctagaa tagagaattt
    10081 cttgtcaaaa tctttttcag gttctgaaat atcgtgattt aattgggtca tcaattctgc
    10141 tttaagaaga aatttaacac atacacctaa agttacactt tgagtatttg tggcactagg
    10201 caatatttct ttatattttt taattccttc tgctacttca tcggacagtg caacgttcaa
    10261 ttttaattcc ttttcttcca ctggataaat attttttaaa gagatagagt tatcttgtac
    10321 aacttttgtc cagtttgtta cagtctttga attttgaaac gcacgcgtta aaatggtagc
    10381 tttagttata ttgatacctt ctgaagtttc atatttctct tttagcattc ttaaatagta
    10441 agctgcttca ccagatattc ggacttgaaa ttgtgtcatt attagtacct ccgtattgta
    10501 ttataccatt tgtacattaa aaggacaatg tataaacgaa taatctacct tctcgttcaa
    10561 gcatttttac aagtttagta atcttgttga agatgcattc catgtgttac gtttaaaaaa
    10621 gggaattaaa gtaatctagt tcctaaaagg ttactaaaaa taaaaaaact atcgtttttg
    10681 tgatagaggt aactttttga aaaggctatt tgactggctt tatatactta tgaaatgtta
    10741 agagcccaac tcaaaatcca gtgtccgcaa ggacgtgccg gttcgacccc ggccgccggt
    10801 atagtatagt gttaggaacg ttgttattct tcgttccttt tttatattat ttttggtata
    10861 attatagtta ttcaaatttt atttagatta agaaagtgta ggggagtatg tcttgttcta
    10921 tcgatttatt aaaacatcgg tatttgaaaa atattaaaga aaatcctgaa ttgtttgtcg
    10981 gaattgagtt ggagtatcct gttgcaagtt tagaagggga tgctacagat gttgaagtta
    11041 taaaggatct atttcattat ttagtttcta ctttggatct caccgtagca aagatagatg
    11101 attttggcaa tctgatccag ttagtagatc cgataagtca ggatgctatt ttatttgaag
    11161 tttcctatac aacgattgag tttgcatttg gtaaggctga aacgattcaa gaggtcgaaa
    11221 atcgtttcaa taattatatg aatgtaattc agagaaagtt agctgaatca aatcatgcta
    11281 ttgttggctg tggtatccat cccaactggg ataaaaatga gaattgtcca gtggcttatc
    11341 cacgctatca gatgttgatg gattatttga atttgagtag aaatattatt aaatcagatt
    11401 tacatcattt ccctgaatat ggtactttta tctgtgggag ccaggttcag ctggatattt
    11461 caaaaaccaa ctacttacgg gtgattaatg cttttactca aattgaagcg gctaaggctt
    11521 atttatttgc aaactctgag ttttcgggtg cggattggga tacgaaaatt tcaagggata
    11581 ttttctggga agaatctatg catggtatct atccagagaa tgttggggtc aatgctagac
    11641 tccttaatga tgaagctgat ttttttgact atctaaatca ttctgcgatt tttactgcgg
    11701 aacgtgatgg gcagacctat tatttttatc ctattcaggc tggggactat ttggctacgc
    11761 ctgaaatcca agcattttct ctgaatgggg atgaggttat tatttacccc caagagaagg
    11821 attttgaaac tcatcgtagt taccagtacc aagacttaac gactcgagga acagttgagt
    11881 ttcgtagtgt gtgtacacag ccacttgata gaacttttgc ttctgcagct tttcacttgg
    11941 gattattggt taatttagac aagttagaag cttacttaga aacagcacct ttctttaaag
    12001 tatttggtta tgattacaag tctttaagga gacaattttc taagaaaaat cttacagatg
    12061 aggaagaaac tacgattatt gaattttcca aagacttact cctactagct gaggagggac
    12121 tagtggtgag aaataaggaa gaaatgacct atttacagcc tttgagagaa gaattgagcc
    12181 tataatttct cttataaagg gagaattttc tgaaaaatca tgatataatg gacgagacta
    12241 tagataaagg atagagagta atgacattag tttatcaatc aacgcgtgat gccaacaata
    12301 cagtaactgc cagtcaagca attttgcaag gtttggcgac ggacggcggt ttgtttacac
    12361 cggttactta tccaaaggta gatttggact ttgacaaatt gaaagatgct tcttaccagg
    12421 aagttgctaa gctagttttg tcagcatttt tagatgactt tacagctgag gagttggact
    12481 actgtatcaa caatgcctac gatagcaaat ttgatactcc agctattgca ccattagtga
    12541 aattagatgg gcaatacaat ttggaacttt tccatggttc aacgattgcc tttaaggata
    12601 tggccttgtc tattttgcca tactttatga cgactgctgc taagaaacat ggtttggaga
    12661 acaagattgt tatcttgaca gcgacatctg gtgacacggg gaaagctgct atggcggggt
    12721 ttgcggatgt gcctggtact gagattatcg tcttttatcc aaaggatggt gtcagcaaga
    12781 ttcaagagtt acaaatgacc actcagactg gcgacaatac tcatgttatt gctattgatg
    12841 gtaactttga cgatgcgcaa acaaatgtga agcacatgtt taacgatgtg gctcttcgtg
    12901 aaaaattgac taccaacaag ttgcaatttt catcagctaa ctctatgaac attggtcgtc
    12961 tggtgccaca aattgtttat tatgtttatg cttacgctca attggttaag actggtgaaa
    13021 ctgtagctgg tgaaaaggtt aacttcacag taccaacagg aaactttgga aatatcttgg
    13081 ctgcctttta tgccaaacaa attggtttgc cagttggtaa attgatctgt gcttcaaatg
    13141 acaacaatgt tttgacagac ttctttaaaa cacgtgtcta tgacaaaaaa cgtgagttta
    13201 aggtaacaac cagcccatct atggatatct tggtatcttc aaacttggag cgcttgattt
    13261 tccatctttt gggaaataat gctgaaaaga cagctgaact catgaatgct ttgaacatgc
    13321 aaggacaata taagttgaca gactttgatg cagagatttt ggacctcttt gcagctgaat
    13381 atgcgactga ggaagaaaca gcggcagaaa tcaagcgtgt ttatgagtta gattcttata
    13441 ttgaggatcc acatacggcg gttgcctcag cagtttatag aaaataccaa gcggttactg
    13501 atgatgcgac taagacagtg attgcttcaa cagctagtcc ctacaagttc ccagtagttg
    13561 cagtagaagc tgtaactgga aaagcaggtt taacagactt tgaagctttg gctcaattac
    13621 atgaaatctc aggcgttgca gtgccaccag cagttgatgg gcttgagaca gctcctgttc
    13681 gtcacaagac aacagtggca gctgctgaca tgcaagtagc ggttgaggct tatttaggac
    13741 tttaagatag agggagtaaa ctcggttggg aaaccaactg agtttctttt catcaggagg
    13801 agagattgtt taagaaaaat aaagacattc ttaatattgc attgccagct atgggtgaaa
    13861 actttttgca gatgctaatg ggaatggtgg acagttattt ggttgctcat ttaggattga
    13921 tagctatttc aggggtttcg gtagctggta atattatcac catttatcag gcgattttca
    13981 tcgctctggg agctgctatt tccagtgtta tttcaaaaag catagggcag aaagaccagt
    14041 cgaagttggc ctatcatgtg actgaggcgt tgaagattac cttactatta agtttccttt
    14101 taggattttt gtccatcttc gctgggaaag agatgatagg acttttgggg acggagaggg
    14161 atgtagctga gagtggtgga ctgtatctat ctttggtagg cggatcgatt gttctcttag
    14221 gtttaatgac tagtctggga gccttgattc gtgcaacgca taatccacgt ctgcctctct
    14281 atgttagttt tttatccaat gccttgaata ttcttttttc aagtctagct atttttgttc
    14341 tggatatggg gatagctggt gttgcttggg gaacaattct gtctcgtttg gttggtcttg
    14401 tgattttgtg gtcacaatta aaactgcctt atgggaagcc aacttttggt ttagataagg
    14461 aactgttgac cttggcttta ccagcagctg gagagcgact tatgatgagg gctggagatg
    14521 tagtgatcat tgccttggtc gtttcttttg ggacggaggc agttgctggg aatgcaatcg
    14581 gagaagtctt gacccagttt aactatatgc ctgcctttgg tgtcgctacg gcaacggtca
    14641 tgctgttggc ccgagcagtt ggagaggatg attggaaaag agttgctagt ttgagtaaac
    14701 aaaccttttg gctttctctg ttcctcatgt tgcccctgtc ctttagtata tatgtcttgg
    14761 gtgtaccatt aactcatctc tatacgactg attctctagc ggtggaggct agtgttctag
    14821 tgacactgtt ttcactactt gggaccccta tgacgacagg aacagtcatc tatacggcag
    14881 tctggcaggg attaggaaat gcacgcctcc ctttttatgc gacaagtata ggcatgtggt
    14941 gtatccgcat tgggacagga tatctgatgg ggattgtgct tggttggggc ttgcctggta
    15001 tttgggcagg gtctctcttg gataatggtt ttcgctggtt atttctacgc tatcgttacc
    15061 agcgctatat gagcttgaaa ggataggaaa tgcaaaaaac agcttttatt tgggatttag
    15121 acgggacttt attggactct tacgaagcga ttttatcagg gattgaggag acttttgctc
    15181 agttttctat tccttatgat aaggagaagg tgagagagtt tatcttcaag tattcggtgc
    15241 aaaatttgct tgtgcgggtg gcagaagata gaaatctgga tgttgaggtg ctaaatcagg
    15301 tgcgtgccca gagtctggct gagaagaatg ctcaggtagt tttgatgcca ggtgcgcgtg
    15361 aggtgctagc ttgggcagac gaatcaggaa ttcagcagtt tatatatact cataagggga
    15421 acaacgcttt taccattctc aaggacttgg gggtggaatc ctattttaca gagattttaa
    15481 ccagtcagag tggctttgtg cggaagccaa gtccagaagc ggctacctat ctgctagata
    15541 agtatcagct ggatcctgag aagacctatt atatagggga ccggacttta gatgtggaat
    15601 ttgccaagaa tagcggtatt caaagcatca actttttaga atcttctttt gaaggcaatc
    15661 acaggattca agcactagca gatatttccc gtatttttga gactaagtga taaaaagatt
    15721 gtgtcagttt tgtgacagag acctaacaaa ctatttcaag taatctagtt tgttacaagg
    15781 aatagacagt tctgttaaat aggcccgaga gggctttttt tctacatttt ttgtgttatg
    15841 atagacaggt actcatttga aaggaatttg aaagaatgaa gaaaagaatg ttattagcgt
    15901 caacagtagc cttgtcattt gccccagtat tggcaactca agcagaagaa gttctttgga
    15961 ctgcacgtag tgttgagcaa atccaaaacg atttgactaa aacggacaac aaaacaagtt
    16021 ataccgtaca gtatggtgat actttgagca ccattgcaga agccttgggt gtagatgtca
    16081 cagtgcttgc gaatctgaac aaaatcacta atatggactt gattttccca gaaactgttt
    16141 tgacaacgac tgtcaatgaa gcagaagaag taacagaagt tgaaatccaa acacctcaag
    16201 cagactctag tgaagaagtg acaactgcga cagcagattt gacaaccaat caagtgaccg
    16261 ttgatgatca aactgttcaa gttgcagatc tttctcaacc aattgcagaa gctccaaaag
    16321 aagtagcatc aaattcagaa gttgcagaga cagtgactgc tgcagaagaa gtggcaccat
    16381 ctacgggcac ttctgtccca gaggagcaaa cggccgaaac aactcgccca gttgaagaag
    16441 tagctcctca ggcaacgact ctagctgaga agcaggaaac acaagtgagc tctcaaaccg
    16501 agtcagcagt ggaagcaact acaatgccag tagaagaaaa agcaaccgaa acaactgcaa
    16561 caagttcaga agcaaaagaa gtagcatcat caaatggagc tacagcagca gtttctactt
    16621 atcaaccaga agagacgaaa acaatttcaa caacttacga ggctccagct gcgcccgatt
    16681 atgctggact ggcagtagcg aaatctgaaa atgcaggtct tcaaccacaa acagctgcct
    16741 ttaaagaaga aattgctaac ttgtttggca ttacatcctt tagtggttat cgtccaggag
    16801 acagtggaga tcacggaaaa ggtttggcta tcgactttat ggtaccagaa agttcagaat
    16861 taggggataa gattgcggaa tatgctattc aaaacatggc cagccgtggc attagttaca
    16921 tcatctggaa acaacgtttc tatgctccat tcgatagcaa atatgggcca gctaacactt
    16981 ggaacccaat gccagaccgt ggtagtgtga cagaaaatca ctatgaccac gttcacgttt
    17041 caatgaatgg ataaacccga cttggtaaca tcattttgac gaatgagatc tagctttcgt
    17101 gataggaagc gattctcgtt cgttttttct ttgtcatact cttcgaaaat ctcttcaaac
    17161 aacgtcagtt ttatctgaaa cctcaaagct gtgctttgag caacctgcga ctagcttcct
    17221 agtttgcttt ttgattttca ttgagtatca atttgaatgg aaaatggaaa gttatcatct
    17281 tgtaatgagt taagcaacat tcttgcaatc tattttatag tagattgaaa ctagaatagt
    17341 acacaactgc ttctaaaaca ttgttagaaa tcgatttgac tgtcctgatc gatttgtcct
    17401 gctcttattt catttcacta tactttatat tataattgac tggtcaaata ttgataaatc
    17461 aataaaaaga gaggggaaga aatgctagag attcaagatt tactgtatca actccgcttg
    17521 tctgagcaag tgagtacgca attgtttgaa aaagcttggg attagtttga cacggtatca
    17581 gattttactg tttttgctgg agcattctct ttgtaaccaa atggcggttc aggagcgttt
    17641 gaaaattgat caggctgctt tgacacggaa tttcaagatt ttggaaacgg aaggtttggt
    17701 ggagcgtcat cgtaatcctg aaaatcagcg ggaagtattg gtagaggctg cgaagtatgc
    17761 caaggagcag ttagtggtga atccccctct gcaacatatc aaggttaagg aagagatgga
    17821 aagtatctta acagagtttg agagaacaga actcagccgt ttattaaata aattggtttt
    17881 gggtattgaa aatatagaaa tttaaggaga aatagatgtc aattattaca attattttaa
    17941 caacgatcgt tgcttgggag catttttaca ttttttattt agaaagtatt gccacgcaat
    18001 cagatgcgac tagtcgtgta tttaatatgg aaagggaaga attggctcat ccgtcagtaa
    18061 gtttattgtt caaaaatcaa gggatttata aggctctgct aggagtctgt ctcttgtatg
    18121 gcatttattt ctcacagaat ttagaaattg tgactatttt tgtcttattt gtgattggtg
    18181 ctgcgactta cggctcttta acagcggata aaaaaattat tttgaaacaa ggtggatcag
    18241 ctattttggc cttgattagt attttactct ttaaatacac ttgaaggtcg attctaatct
    18301 cgctaatcct ttttaatcca gaataaggga aatatgttat acttgttttt aagaaaaaag
    18361 tttcattgaa ttggttttga ggagttagaa atgaaagtat tagtgacagg ttttgagccc
    18421 ttttgaggcc attaaaggtt taccagctga aatccatggt gctgaggtcc gttggctaga
    18481 ggtgccgaca gtttttcaca aatctgctca agtattggaa gaagagatga atcgttatca
    18541 acctgacttt gtcctttgta ttgggcaagc tggtggaaga actagtttga cacctgaacg
    18601 agtggccatt aatcaagacg atgcacgtac ttctgataac gaagataatc aaccgattga
    18661 ccgtcccatt cgcccagatg gtgcttcggc ctactttagt agtttgccga ttaaagcgat
    18721 ggttcaagct ataaaaaaag agggcttacc ggcctctgtt tccaatacgg cagggacttt
    18781 tgtctgcagc catttgatgt atcaggctct ctatttggta gaaaagaaat ttccatatgt
    18841 taaggcaggt tttatgcata ttccttatat gatggaacag gtggtgaaca gaccgactac
    18901 tccagctatg agtttagtgg atattcggcg agggatagaa gcagcaatcg gcgctatgat
    18961 agaacatgga gatcaggaac tcaagttggt aggcggagaa actcattgat agaaaaaagc
    19021 ttgaggggaa aaaccttcaa gcttttggac gttttcgagc caatactgct cggtaaaaca
    19081 taattttagt gcattggata taaggtagga gtgaaaaact agcaatgcca aaggtaatcc
    19141 aattgaggaa gtaccaagga agaagctgta aatctaggac aaagcgctgg aacttgtagc
    19201 ccttcataaa ggaacggcta gtttttagga ttcgtcttgg tgggacctgt cctaggtcta
    19261 gactataaca gagaagaaat tccacctgtg aataggcata atactgtgga atatagagga
    19321 tatttcctac aatgatcaag atgagacttg caagaaagta gagtccaaag accatgagga
    19381 aacgctcggt ttcaactgat gagagatcta gatttggaaa ctcaggatgt agggtgacga
    19441 attttttggc taaaaagcta ctataaaaga ggaggtaaat cccaagtaaa ttagggatac
    19501 tccataaaaa gagatagaaa cgtttgagaa gtagggtcaa aaaggtttga gaaaagcgct
    19561 cctcatcaaa gagagctagg ctgtttttta cagatggctc cgttttagaa tctttcatga
    19621 gtgtcagtgt tgcatagacg gaactggtca aaagaatagt cccgataaag gagactagta
    19681 gaggaaagag gtaggtttga agtatttggc caagtatgct gaaaaatggc tgttctaaaa
    19741 cagtcccgtg gatccgagat aagggattaa gaaaactaga taagatgacc agcatactgg
    19801 gaaggatata gaggagaaag agacgggggg tgtcagcctg aaaatgtttt gactcctgac
    19861 gaattgtttt taaatcaatt tttggatagt tcattctctt attataccat agttcttata
    19921 catagttcgt gacagttcct actttttttg ataaaatcat acagtgtgtc cttgggcaca
    19981 ctgtatgaac tgggactgtc tttcccagct tcggaggtaa aaaatgtcag attcaccaat
    20041 caaatatcgt ttgattaaga aagaaaaaca cacaggagct cgtctaggag aaatcatcac
    20101 tccccacggt acctttccga cacctatgtt tatgccagtt gggacacaag ccactgtcaa
    20161 aactcagtca cctgaagaat tgaaggagat gggttcggga attatcctat caaacaccta
    20221 tcatctctgg cttcgccctg gagatgaact cattgcacgc gctggtggtc tccacaagtt
    20281 catgaattgg gaccagccta tcttgacaga tagtggtggt tttcaggttt attctttagc
    20341 agatagccgt aatatcacag aagaaggagt aacctttaaa aatcatctaa atggttctaa
    20401 gatgctccta tccccagaaa aagccatctc tattcagaat aatctgggtt cagacatcat
    20461 gatgtccttt gatgaatgtc ctcagtttta tcaaccttat gactacgtta agaaatcgat
    20521 cgagcgtacc agccgttggg ctgagcgtgg tttgaaggct caccgtcgtc cacatgacca
    20581 aggtttgttt ggaattgtgc aaggtgcagg atttgaagac cttcgccgcc aatcagctca
    20641 tgatcttgtc agcatggatt tctcaggcta ctctatcggt ggtttggcag tgggagaaac
    20701 ccatgaagag atgaatgcgg tcttggactt tacaactcaa ctgctgcctg aaaataaacc
    20761 tcgttatctg atgggtgtgg gagcgccaga tagcttgatc gatggggtca ttcgtggggt
    20821 ggatatgttt gactgtgtct taccgactcg aattgctcgt aacgggactt gtatgaccag
    20881 tcaaggacgt ttggttgtga aaaatgccca gtttgctgag gactttacgc cactggatcc
    20941 tgagtgtgat tgctacacat gtaataacta tacacgcgct taccttcgtc acctgctcaa
    21001 ggctgatgaa acctttggta tccgcttgac tagctaccac aatctttact tcttgcttaa
    21061 cctgatgaag caagtgcgac aagccatcat ggatgacaat ctcttggaat tccgtaagta
    21121 ttttgtggaa aaatatggct ataataagtc aggacgtaat ttctaaaatg gaattgatat
    21181 aagctaaaaa tcctaagttt tctcttagga tttttcttct ttttttgata gaataaagtg
    21241 tacaatgaaa ggaagaataa actcgtatgc gcattaaatg gttttccttg gttaggatta
    21301 caggtttact tttggtactc ttgtatcact tctttcagac gatctttcct ggaggatttt
    21361 tcggggtaga tgtctttttc acattttcag gtttcctgat tacagctcta ctcattgaag
    21421 aattttctaa aaaccatgag attgatttga taggattttt tagaagacgc ttttatcgga
    21481 ttgtgccacc tgtggttttg atggtcttgg tgaccatgcc ttttactttc ttggttcgcc
    21541 aagactatgt tgctggaatt ggtggccaga ttgcgagcgt cttaggcttt atgaccaact
    21601 tctatgaact cctaacaggt gggagttatg aatctcagtt cattcctcat ttgtttgttc
    21661 ataattggag tttggcagtt gaggttcact actatattct ttggggattg gcagtttggt
    21721 tcttatccaa acaagctaaa tcaaatggtc agttgaaggg gatggtcttt ctcttatctg
    21781 ctgttgcctt cttgatcagt ttcttctcca tgtttattgg tagttttcta gtgacctctt
    21841 attcctctgt ttatttctcc agtttaactc atgtctatcc attctttttg ggaagtatgt
    21901 tagcaactat tgtaggcgtt cgtcagacga cttccctcgt caagcagttg gataaaatct
    21961 gggatttacg aaagactttg gtagtttttg gaggaggctt tggtttccta gttcttttga
    22021 ctttctttgt caaattcact tatctttttg cctatcttat cggcttctta cttgccagtc
    22081 ttgcagctct tgccatgatt ctggcggcgc gtgtcttaca tgaaaagaca catcatatac
    22141 aggagccgaa gattatcagc tttttagcgg atactagcta tgcggtttat cttttccatt
    22201 ggcctttcta tatcattttc tcacagttga catcaaatct tcttgctgta ttactgactc
    22261 tgatttgttc ttatggcttt gccagtctgt cattctatgt attggaacct tggattgcag
    22321 gcaagaacac acctattgtc caaacccttc gtcccctgcc ttatattcac gcaattcttg
    22381 cagcaggtac aggaatcttg accatcattg tctgcacggt gaccttgttg gcaccacaag
    22441 tgggagcgtt tgagacagac ttgactgtca atggcttgaa gcaagctgca acaaatattg
    22501 gccagaccaa ggtgatggca gaacgggcag atgcaaacag tttgggaatt gctgatggca
    22561 ctatgttaat tggtgactca gtggctttaa gggcaaatac agcactacag acagctcttc
    22621 ctggagcaca gattaacgcg caggtcagcg taacaaccaa gaccgcaaat gaaatcatgc
    22681 taaataatag ccagaataaa tttttaccta agacggtggt cattgcgact ggggtaaata
    22741 atcctgagaa ttacaaggat gactgggaca gtatcgtgaa aaatcttcct aagggacacc
    22801 atatgatttt ggtgactcct tatgagggag ataagacaaa agagacctat gccatcgttg
    22861 agaaggctgc tgcctatatg agagaattgg cagagaagac accttacatt acgatagcag
    22921 attggaatca agttgcgaaa gagcatccag aaatttgggc aggaacagac caggttcatt
    22981 tcgggagtga gagtagcact atcgaagcag gagcaaaatt gtatgcagat acgattgcca
    23041 cagctttgca gacagctcaa gacaagccgg ttaaatcaaa ataacttgta ttaaaaaaga
    23101 gaagagttgg agaaatccag ctcttttaaa atatctccaa aaaataggtc tataccattt
    23161 acaaataaaa aagaaaggtt tataatgtaa ttgacataat aaattgtaga atcaatcttt
    23221 taaggaggtt aacattatgc ctaactatat taaagcggat cagtttttct acccacacgg
    23281 agttcgtcga ggtggttact tggaacttgt ggacggcaag tttgggaaac atgtagagca
    23341 gattcctgaa ggggctgagg tgattgacta tacaggttat agcattgccc caggtcttgt
    23401 ggatactcat attcatggat atgcaggtgt agatgtgatg gacaacaaca ttgaaggtac
    23461 attgcatact atgagtgaag gacttcttag taccggtgtt accagtttct tacccacaac
    23521 tttaacagcc acttatgagc aattgcttgc agtcactgaa aatcttggaa accattataa
    23581 agaagcaaca ggtgctaaga ttcgtgggat ttattatgaa ggtccatatt tcacagaaac
    23641 ttttaagggg gcacaaaatc caacttatat gagagacccg ggtgttgagg agtttcattc
    23701 ttggcaaaaa gcggcaaatg gcttgcttaa taaaattgcc cttgcaccag aacgtgatgg
    23761 ggtggaggac tttgttcgta cagttacggg cgaaggtgtg acggttgctc ttggacattc
    23821 aaacgcgact tttgatgaag ccaaaaaagc agtcgatgct ggagcgagtg tttgggtgca
    23881 tgcctacaat ggaatgcgtg ggttgactca ccgtgaattg ggtatggttg gagccatgta
    23941 ccaattgcca catacctatg cagagttgat ctgtgatggc caccacgtag atccaaaggc
    24001 ttgcgaaatt cttatcaaac aaaaaggaac agaaaacatc gctcttatca cagactgtat
    24061 gacagctggg ggattggaag acggagatta tatgttggga gaattcccag ttgtcgttgc
    24121 aaatggaact gcacgcctca aatcgacagg taacttggca ggttctatcc tcaaactcaa
    24181 agatggtttg aagaatgtgg tcgaatgggg aattgcgaat ccgcatgaag cagtcatgat
    24241 ggccagcttc aacccagcta aatccgttca catcgatgat gtctgtggcc aaatccgtga
    24301 aggctacgac gctgacttca tcgtattaga taaagatttg gaattggtag caacctacct
    24361 agatggcgta aaacgttatc aagcataaga gagaaagcag aagttagaga ctaacttctg
    24421 cttttttatg cagggtactt tactggtaaa taaaaagtta aaaaaatcac aaaaaaagct
    24481 tgaagaaaca aagaaaaagg cttacaattg aactataaat attacaaata aaaaaacgga
    24541 ggagtgcttt atgaaagcct atacttatgt taaaccagga cttgcttctt ttgttgatgt
    24601 agacaaacca gttattcgca agccaacaga tgctattgtg cgtattgtaa aaaccactat
    24661 ttgtggaaca gacctccata ttatcaaagg ggatgttcct acttgccaaa gtggtaccat
    24721 tcttggccac gaagggattg ggattgttga agaagttggg gaaggagttt ccaacttcaa
    24781 aaaaggtgac aaggtcttga tttcttgcgt ctgtgcctgt ggtaaatgct actactgtaa
    24841 aaaaggaatt tatgctcact gtgaagacga agggggctgg attttcggtc acttgattga
    24901 tggtatgcag gctgaatatc tacgtgtccc tcatgcagat aatactcttt accatactcc
    24961 agaagacttg tcagatgaag ctttggttat gctgtcagac attctgccta ctggatatga
    25021 aattggtgtc ttaaaaggga aagtagaacc tggttgcagc gtagccatta ttggttcagg
    25081 tccagttgga ttggctgctc ttttaacagc ccaattctat tcaccagcta aattgattat
    25141 ggtagaccta gacgataacc gcttggaaac tgccctatca ttcggtgcga ctcataaggt
    25201 taattcttca gaccctgaaa aagccattaa agaaatttat gatttgacag atggtcgtgg
    25261 tgtggatgtc gctatcgaag ctgttggtat tcctgcaaca tttgatttct gtcaaaagat
    25321 tatcggtgta gacggaacgg ttgccaactg tggtgtgcat ggtaaaccag ttgaattcga
    25381 tttagataaa ctttggattc gcaacatcaa tgtaacaact ggtttggtat ctacaaatac
    25441 gactccacaa ttgttgaaag cacttgaaag tcataagatt gaaccagaaa aattggtaac
    25501 tcactatttc aaactcagtg aaattgaaaa agcctatgaa gtcttcagta aggcagcaga
    25561 ccaccatgcc attaaggtca ttatcgaaaa cgatatctca gaagcctaag tagtaaaaat
    25621 atttttgtac ataagtaaat agaaattcag tcatccatca gatggctgga ttttttatca
    25681 aaaaattaag aaatgagcat atttctttcc ttgtctggcg gaattggtta taatatacgg
    25741 tacaaaggaa tgaatgaata tgtatcgtgt tatagaaatg tacggagatt ttgaaccgtg
    25801 gtggttctta gaaggttggg aagaagatat tgtagcaagt agaaaatttg accagtatta
    25861 tgatgctctc aaatactaca aaacttgctg gtttagattg gaacaagaat cccctcttta
    25921 taaaagtaga agcgacttga tgaccatttt ttgggacccg gaagaccaac gctggtgtga
    25981 tgaatgtgat gagtatttac aacaatacca ttctttggct cttttgcagg atgagcaggt
    26041 tatcccagac gaaaaactac gctcaggcta tgaaaaacaa accagtcagg aaaggaatcg
    26101 ttcttgccgt atgaaattaa aatagagaaa agtaactttt ttggagttgc tttttttatt
    26161 tttctaacgc tttgcgaata gtataggtga ggaggtaagt atggttcaag aaattgcaca
    26221 agaaatcatt cgttcagctc ggaaaaaagg gacgcaggat atttattttg tccctaagtt
    26281 agacgcctat gagcttcata tgagggtagg agacgagcgc tgtaaaattg gtagctatga
    26341 ttttgaaaag tttgcagccg ttatcagtca ctttaagttt gtggcgggta tgaatgtggg
    26401 agaaaaaaga cgtagtcaac tgggttcctg tgattatgcc tatgaccaga agatggcgtc
    26461 tctacgttta tctactgtag gcgattatcg gggacatgag agtttggtta tccgtttgtt
    26521 gcacgatgag gagcaggact tgcatttttg gtttcaggat attgaagaat taggcaagca
    26581 gtacaggcaa cggggactct atctttttgc tggcccggtt gggagtggta agacgacctt
    26641 gatgcatgaa ttgtccaagt cactctttaa aggacagcaa gttatgtcca tcgaagatcc
    26701 tgtcgaaatc aagcaggacg acatgcttca gttgcagttg aacgaagcaa tcggcctaac
    26761 ctatgaaaat ctaatcaaac tttccttgcg tcatcgacca gatctcttga ttatcggaga
    26821 aattcgtgac atcgagacgg cgcgtgcagt ggtcagagct agtttgacag gtgcgacagt
    26881 cttttcaacc attcacgcca agagtatccg aggtgtttat gagcgtctgc tggagttggg
    26941 tgtgagtgaa gaagaattgg cagttgttct gcaaggagtc tgctaccaga gattaatcgg
    27001 gggaggagga atcgttgact ttgcaaacag agattatcaa gaacaccaag cagccaagtg
    27061 gaatgagcaa attgaccagc ttcttaaaga tggacatatc acaagtcttc aggctgagac
    27121 ggaaaaaatt agctacagct aagcaaaaaa atatcatcac cctatttaac aatctctttt
    27181 ctagcggttt tcatctggtg gagactatct cctttttaga taggagttcc ttgttggaca
    27241 agcagtgtgt gacccagatg cgtacaggct tgtctcaggg gaaatcattc tcagaaatga
    27301 tggaaagttt gggatgttca agtaccattg tcactcagtt atctctagct gaagttcatg
    27361 gcaatcttca cctgagtttg ggaaagatag aagaatatct agacaatctg gccaaggtca
    27421 agaaaaagtt aattgaagta gcgacctatc ctttgatttt gctgggtttt cttctcttaa
    27481 ttatgctggg gctacggaat tacctgctcc cacaactgga tagtagcaat attgccaccc
    27541 gaattatcgg taatctgcca caaatttttc taggcatggt agggcttgtt tccgtgcttg
    27601 cccttttagc actaactttt tataaaagaa gttctaagat gagtgtcttt tctatcttag
    27661 cacgccttcc ctttattgga atctttgtgc agacctactt gacagcctat tatgcacgtg
    27721 aatgggggaa tatgatttca cagggaatgg agctgacgca gatttttcaa atgatgcagg
    27781 aacaaggttc ccagctcttt aaagaaatcg gtcaagatct ggctcaaacc ctgaaaaatg
    27841 gccgtgaatt ttctcagacg ataggaacct atcctttctt taggaaggaa ttgagtctca
    27901 tcatagagta tggggaagtt aagtccaagc tgggtagtga gttggaaatc tatgctgaaa
    27961 aaacttggga agcctttttt acccgagtca accgtaccat gaatttggtg cagccactgg
    28021 tttttatctt tgtggcactg attatcgttt tactttatgc ggcaatgctc atgcccatgt
    28081 atcaaaatat ggaggtaaat ttttaaaatg aaaaaaatga tgacattctt gaaaaaagct
    28141 aaggttaaag cttttacatt gattgagatg ttggtggtct tgctgattat cagcgtgctt
    28201 ttcttgctct ttgtacctaa tctgaccaag caaaaagaag cagtcaatga caaaggaaaa
    28261 gcagctgttg ttaaggtggt ggaaagccag gcagaacttt atagcttaga aaagaatgaa
    28321 gatgctagcc taagaaagtt acaagcagat gggcgcatca cggaagaaca ggttaaagct
    28381 tataatgaat actatactaa aaatggaggg gcaaatcgta aagtcaatga ttaaggcctt
    28441 taccatgctg gaaagtctct tggttttggg acttgtgagt atccttgcct tgggcttatc
    28501 cggctctgtc cagtccactt ttgcagcagt agaggagcag attttcttta tggagtttga
    28561 agaactctat cgggaaaccc aaaaacgcag tgtagccagt cagcaaaaga ctagtctaaa
    28621 tttagatggg cagacgctta gcaatggcag tcaaaagttg acagttccta aaggaattca
    28681 ggcaccatca ggccaaagta ttacatttga ccgagctggg ggcaattcgt ccctggctaa
    28741 ggttgaattt cagaccagta aaggagcgat tcgctatcaa ttatatctag gaaatggaaa
    28801 aattaaacgc attaaggaaa caaaaaatta gggcagtgat tttactggaa gcagtagtcg
    28861 ctctagctat ctttgccagc attgcgaccc tccttttggg acaaattcaa aaaaataggc
    28921 aagaggaagc aaaaatcttg caaaaggaag aagtcttgag ggtagctaag atggccttgc
    28981 agacaggtca aaatcaggta aacataaacg gagttgagat tcaggtgttt tctagcgaaa
    29041 agggattgga ggtctaccat ggttcagaac agttgttggc aatcaaagag ccataaggtc
    29101 aaggctttta ccttgttaga atccctgctt gccctgattg tcatcagtgg gggcttactc
    29161 ctttttcaag ctatgagtca gctcctcatt tcagaagttc gctaccagca acaaagcgag
    29221 caaaaggagt ggctcttgtt tgtggaccaa cttgaggcag aattagaccg ttcgcagttc
    29281 gaaaaagtag aaggcaatcg cctatacatg aagcaagatg gcaaggacat cgccatcggt
    29341 aagtcaaagt cagacgattt tcgtaaaacc gatgctagtg gacgggggta tcagcctatg
    29401 gtttatggcc tcaaatcagc tcagattaca gaggacaatc aactggttca ttttcgtttc
    29461 cagtttcaaa aaggcttaga aagggagttc atctatcgtg tggaaaaaga agaaagttaa
    29521 ggcaggtgtt ctcctctacg cagtcaccat agcagccatc tttagtcttt tgttgcaatt
    29581 ttatttgaac cgacaaatcg cccactatca agactatgct ttaaataaag aaaaattggt
    29641 tgcttttgcc atggctaaac gaaccaagga taaagccgag caagaaagtg gggaacaggt
    29701 ttttaatcta ggtcaggtaa gctatcaaaa caagaaaaca agcttggtga cgactgttcg
    29761 tacgtctaag agccaatatg agtttctgtt tccttcagtc aaaatcaaag aagagaaaag
    29821 agataaaaag gaagaggtag cgaccgattc aagcgaaaaa gcggagaaaa aaaatcagaa
    29881 gagaagcctg aaaagaaaga gaattcctag tcaattcaac tataatgcgt tgaatccaga
    29941 atagtccact gtagtttcta gaaaattgct ggaaatggat gttaagctcc aattcatttg
    30001 tttatatctt atttcagttt actatacttt gtgctaaatt aaagatatga aacatgattt
    30061 taaccacaaa gcagaaactt tcgattcccc taaaaatatc ttcctcgcaa acttggtatg
    30121 tcaagcagcc gagaaacaga ttgatcttct atcagacaaa gaaattttag atttcggtgg
    30181 tgacacgggt ctattagcct tgcccctagc ccctagccaa gcaggctaag tcagtcactc
    30241 ttgtagacat ttctgagaaa atgttggagt aagctcgttt gaaagcggag cagcaagcaa
    30301 tcaagaatat ccagtttttg gagcaagatt taccgaaaaa tcccttggag aaagagtttg
    30361 attgccttgc tgttagtcgg cttcttcatc atatgcctga tttggatgcg gatctctcac
    30421 tgtttcatca acatttgaag gaagatagga aactcatcat tgctgatttt accaagacag
    30481 aagctaatca tcatggattt gatttagctg aactggaaaa caagctaatt gagcatggtt
    30541 tttcatctgt gcatagtcag attctctata gcgctgaaga cctgtttcaa gggaatcact
    30601 cagaattctt tttaacagta tcccaaaaat cactcgccta gtcagggagt gatttttcta
    30661 taaggatgga aaaaagaagg gaaatttgat aagataggaa tatggatttt gaaaaaattg
    30721 aacaagctta tatctattta ctagagaatg tccaagtcat ccaaagtgat ttggcgacca
    30781 acttttatga cgccttggtg gagcaaaata gcatctatct ggatggtgaa actgagctaa
    30841 accaggtcaa agacaacaat caggccctta agcgtttagc actacgcaaa gaagaatggc
    30901 tcaagaccta ccagtttctc ttgatgaagg ctgggcaaac agaacccttg caggccaatc
    30961 accagtttac gccagatgct attgccttac ttttggtatt tattgtggaa gagttgttta
    31021 cagaggagga aattactatc ctcgaaatgg gttctgggat gggaattcta ggcgctactt
    31081 tcttgacctc gcttgataaa aaggtggatt acttgggaat ggaagtggat gatttgctga
    31141 ttgatctggc agctagcatg gcagatgtaa ttggtttgca ggctggcttt gtccaaggag
    31201 atgccgttcg cccacaaatg ctcaaagaaa gcgatgtggt catcagtgac ttgcctgtcg
    31261 gctattatcc tgatgatgcc gttgcgtcgc gtcatcaagt tgcttctagc caagaacata
    31321 cttacgccca tcacttgctc atggaacaag ggtttaagta ccttaagtca gatggatatg
    31381 ctatttttct agctccgagt gatttgttga ccagtcctca aagtgatttg ttgaaagtct
    31441 ggttgaaaga ggaggcaagt ctggttgcta tgattagttt acctgaaaat ctctttgcta
    31501 atgctaaaca atctaagact atttttatcc tacagaagaa aagtgaaata gcagtggagc
    31561 cttttgttta tccacttgct agcttgcaag atgcaagtgt tttaatgaaa tttaaagaaa
    31621 attttcaaaa atggactcaa ggtactgaaa tataaaatag attttgttat aatagttgaa
    31681 aacgcttaaa aaggggtatc atgttatgac aaaaacaatt gcaatcaatg caggaagttc
    31741 aagtttgaaa tggcaattat acttaatgcc agaggaaaaa gtgttagcca aaggtttgat
    31801 tgaacgtatc ggtttgaaag attcaatttc aactgtaaaa tttgacggcc gttctgaaca
    31861 acaaattttg gatattgaaa atcatacaca agccgttaaa attttattgg atgacttgat
    31921 tcgtttcgat attatcaagg cttatgacga gattacaggt gttggacatc gtgttgttgc
    31981 tggtggagaa tatttcaaag aatcaacagt tgttgaggga gatgttttag aaaaagttga
    32041 agagttgagt ttgttggctc ctctacacaa cccggccaat gcagcaggtg ttcgtgcctt
    32101 caaggaattg ttgccagaca ttaccagtgt agttgttttt gatacttcct tccacacaag
    32161 tatgccagag aaagcttatc gctaccctct accaacaaaa tattacacag aaaacaaggt
    32221 tcgtaaatac ggtgctcatg gtacaagtca ccagtttgta gcaggagaag ctgcaaaact
    32281 cttgggacgt ccattagaag acttgaagtt aattacctgt catattggta acggaggctc
    32341 aattacagct gtgaaagccg gcaaatctgt agacacttct atggggttca ctcctcttgg
    32401 tggtattatg atgggaacgc gtacagggga tattgatcca gctatcattc cttatttaat
    32461 gcaatataca gaggatttta acacaccaga agatatcagt cgtgttctta accgtgaatc
    32521 aggtcttttg ggagtttctg ctaattctag cgatatgcgc gatatagaag cagctgtagc
    32581 agaagggaat cacgaggcta gcttggctta tgaaatgtat gttgaccgta tccaaaaaca
    32641 tatcggtcag taccttgcag tgctaaatgg agcagatgtc attgttttca cagcaggtgt
    32701 cggtgaaaat gcagagagtt tccgtcgtga tgtaatctca gggatttcgt ggtttggttg
    32761 tgatgttgat gatgaaaaga atgtctttgg cgttacagga gacatctcaa cagaggcagc
    32821 taaaatccgt gtcttggtta ttccaacaga tgaagaatta gtcattgccc gtgacgttga
    32881 acgcttgaaa aaataagtga aactaaaaaa atattcaata caaggagttg ggaaagttat
    32941 ttttccagct tctttttctg atgaaattgt ccaaaacctt gctatgattg gcttttttga
    33001 aaaatatggt ataatagtag taatttaata gatggagttg agttttgaag aaaaactttc
    33061 gtgtaaaaag agagaaagat tttaaggcga ttttcaagga ggggacaagt tttgctaatc
    33121 gcaaatttgt ggtctaccaa ttagaaaacc agaaaaacca ttttcgagta ggtctatcag
    33181 ttagcaaaaa actggggaat gccgtcacta gaaatcaaat taagcgacgg attcggcata
    33241 ttatccagaa tgcaaaaggg agtctggtag aagatgtcga ctttgttgtc attgctcgaa
    33301 aaggagtcga aaccttggga tacgcagaga tggagaaaaa tctactccat gtattaaaat
    33361 tatcaaagat ttaccgggaa ggaaatggga gtgaaaaaga aactaaagtt gactagtttg
    33421 ctaggactgt ctctgttaat catgacagcc tgtgcgacta atggggtaac tagcgatatt
    33481 acagccgaat cggctgattt ttggagtaaa ttggtttact tctttgcgga aatcattcgc
    33541 tttttatcgt ttgatattag tatcggagtg gggattattc tctttacggt cttgattcgt
    33601 acagtcctct tgccagtctt tcaggtgcaa atggtggctt ctaggaaaat gcaggaagct
    33661 cagccacgca ttaaggcgct tcgagaacaa tatccaggtc gagatatgga aagcagaacc
    33721 aaactagagc aggaaatgcg taaagtattt aaagaaatgg gtgtcagaca gtcagactct
    33781 ctttggccga ttttgattca gatgccggtt attttggccc tgttccaagc cctatcaaga
    33841 gttgactttt taaagacagg tcatttctta tggattaacc ttggtagtgt ggatacaacc
    33901 cttgttcttc cgattttagc agcagtattc acctttttaa gtacttggtt gtccaacaaa
    33961 gctttgtctg agcgaaatgg cgctacgact gcgatgatgt atgggattcc agtcttgatt
    34021 tttatctttg cagtttatgc gccaggtgga gtcgccctat actggacagt gtctaatgct
    34081 tatcaagtct tgcaaaccta tttcttgaat aatccattca agattatcgc agagcgcgag
    34141 gccgtagtac aggcacaaaa agatttggaa aatagaaaaa gaaaagccaa gaaaaaggct
    34201 cagaaaacga aataaataag gaggaatctg gtaatggtag tatttacagg ttcaactgtt
    34261 gaagaagcaa tccagaaagg attgaaagaa ttagatattc caagaatgaa ggctcatatc
    34321 aaagtcattt ctagggagaa aaaaggcttt cttggtctat ttggtaaaaa accagcccaa
    34381 gtggatattg aagcgattag tgaaacgact gttgtcaaag caaatcaaca ggtagtaaaa
    34441 ggcgttccga aaaaaatcaa tgatttgaac gagcctgtga agacggttag tgaagaaacc
    34501 gttgaccttg gtcatgtagt tgatgctatt aaaaaaatag aggaagaagg tcaaggtatt
    34561 tctgatgaag tcaaggctga aatcttaaaa catgaaagac atgccagcac tatcttagaa
    34621 gaaactggtc acattgagat tttaaatgaa cttcaaatcg aggaagcgat gagggaagaa
    34681 gcaggcgctg atgaccttga aactgagcaa gaccaagctg aaagtcaaga actagaagac
    34741 ttgggcttga aagttgaaac gaactttgat attgaacaag tagctacgga agtaatggct
    34801 tatgttcaaa cgattattga tgacatggat gttgaggcta cactttcaaa tgattataac
    34861 cgtcgtagca tcaatttgca aattgatact aacgaaccag gtcgtattat cggctaccat
    34921 ggtaaagtct tgaaggcctt gcaactgttg gctcaaaatt atctttacaa ctgctattca
    34981 agaaccttct atatcactat taatgtcaat gattatgttg aacaccgtgc agaagtcttg
    35041 cagacctatg cgcaaaaatt ggcgattcgt gttttagaag aaggacgtag tcatcaaaca
    35101 gatccaatgt cgaatagtga acgcaagatt atccaccgta ttatttcacg tatggatggc
    35161 gtgaccagtt actctgaagg tgatgagcca aatcgctatg tcgttgtaga tacagaataa
    35221 gtaaaatcag ggttgacctg attttttgct agctagagga ggttaaactg atgttgaata
    35281 agataagaga ctatttagac tttgctggtt tgcagtaccg taatcctgat aaagcgggag
    35341 cagagcgaga gaagatgctg gcattccgcc acaaaggaca agaggcccga aaggctttta
    35401 cagaactggc caaagccttt caagcaagcc atccagaatg gcaactccaa cagactagtc
    35461 agtggatgaa tcaggcccag cgtttgagac cacatttttg ggtttatcta cagagagacg
    35521 gacaagtgac agaacctatg atggccttac gtttgtatgg gacatctact gactttggaa
    35581 tttctttgga agtcagtttc atcgaacgta agaaggatga gcaaacactg ggcaagcagg
    35641 ccaaagtttt agacattcca accgttaaag ggatttatta tctaacctac tctaatggtc
    35701 aaagtcaacg gtgggaggcg aatgaagaaa agcgtcgtac tttacgcgag aaggtgagaa
    35761 gtcaagaagt tcgaaaagtt ttagtgaagg tagatgttcc tatgacagaa aattcgtctg
    35821 aagaagaaat cgtagaaggc ttattgaagt cttattctaa aattcttccc tattatctag
    35881 ctacgagaaa ataagataat ttgtaaaaca tcataaatca tacagtccaa gagtgaacag
    35941 tccgctgtgt aattcttggt ctttttgttt gcgctttcgc attatataat aaacttacaa
    36001 aaacaattca aaaggagaac aattatggaa gtcgtttcaa gtgttctaaa ttggttttct
    36061 agcaatattt tgcagaatcc cgcatttttc gtaggtttat tggtgttgat aggatatgca
    36121 cttttgaaaa aacctgccca tgacgttttt tcagggtttg ttaaagcaac agtagggtat
    36181 atgttgctta acgtgggtgc tggtggtttg gttacaacct ttcgtccaat cttagcagct
    36241 cttaactaca aattccaaat tggtgcagcg gttatcgacc cttactttgg acttgctgca
    36301 gcaaacaaca aaattgcagc agagtttcca gattttgttg gaactgcaac tacagctcta
    36361 ttgattggtt ttggaataaa tatcttgctc gtagctcttc gaaagattac gaaggtaaga
    36421 accctcttta ttactggtca catcatggta caacaagctg caacagtatc tcttatggtt
    36481 ctattcttag taccacaatt gcgcaatgct tacggtacag cagcgattgg tatcatctgt
    36541 ggactttact gggcagttag ttcaaatatg actgttgagg caactcaacg cttgactggt
    36601 ggtggcggat ttgcgattgg tcaccaacag caatttgcaa tctggtttgt agataaagta
    36661 gcaggacgct ttggtaagaa agaagaaagt ttagacaatc ttaaattacc taagttcctc
    36721 tcaatcttcc acgatacagt tgttgcatct gctaccttga tgctcgtatt cttcggagcc
    36781 attctttta
//
LOCUS       DAVHLA010000016        35016 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVHLA010000016 DAVHLA010000000
VERSION     DAVHLA010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35016)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35016)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35016
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.016"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            19..213
                     /locus_tag="VVO77_000948"
     CDS             19..213
                     /locus_tag="VVO77_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEU5692978.1"
                     /translation="MEAEAIRRNCERGAIFSGKIKYHEDSQFKGDHYVECYAVLDNTV
                     IARDRITVPIDPLCGKDFIE"
     gene            458..1792
                     /gene="trmFO"
                     /locus_tag="VVO77_000949"
     CDS             458..1792
                     /gene="trmFO"
                     /locus_tag="VVO77_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEU5692979.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            1876..2613
                     /locus_tag="VVO77_000950"
     CDS             1876..2613
                     /locus_tag="VVO77_000950"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEU5692980.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            2622..3179
                     /gene="frr"
                     /locus_tag="VVO77_000951"
     CDS             2622..3179
                     /gene="frr"
                     /locus_tag="VVO77_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEU5692981.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            3239..4093
                     /gene="cvfB"
                     /locus_tag="VVO77_000952"
     CDS             3239..4093
                     /gene="cvfB"
                     /locus_tag="VVO77_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEU5692982.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            4102..4317
                     /locus_tag="VVO77_000953"
     CDS             4102..4317
                     /locus_tag="VVO77_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEU5692983.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDAIWQEYLEH"
     gene            4403..5371
                     /locus_tag="VVO77_000954"
     CDS             4403..5371
                     /locus_tag="VVO77_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEU5692984.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(5349..5528)
                     /locus_tag="VVO77_000955"
     CDS             complement(5349..5528)
                     /locus_tag="VVO77_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692985.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLRPLDKTFSLYNWIFLSQKYI
                     LLQANFLKISRVQLQ"
     gene            5564..6064
                     /locus_tag="VVO77_000956"
     CDS             5564..6064
                     /locus_tag="VVO77_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU5692986.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGFFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIV
                     EQSLED"
     gene            6067..6326
                     /locus_tag="VVO77_000957"
                     /pseudo
     CDS             6067..6326
                     /locus_tag="VVO77_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(6692..7018)
                     /locus_tag="VVO77_000958"
     CDS             complement(6692..7018)
                     /locus_tag="VVO77_000958"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692987.1"
                     /translation="MVDVAVDQGGVIETADRVTTHDEPVYEKHGVLHYAVANIPGAVA
                     RTSTIALTNVTLPYIEALAGKGFAQAISEDEGLRQGVTTYQGYLTSLPVAQGLNRDYT
                     DINDLV"
     gene            complement(6964..7377)
                     /locus_tag="VVO77_000959"
     CDS             complement(6964..7377)
                     /locus_tag="VVO77_000959"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-binding protein"
                     /protein_id="HEU5692988.1"
                     /translation="MGAHFLTKQAGGSGVLPGGVPGVPKGKVTIIGDGVVGTHAARIA
                     LGLGAQVTILDISAKRLSVLEEVFGSQIQTLISNSFNIEASMRDADVVIGAILIPGAK
                     APELVTDEMVKQMRPGSVSLTLLLTKVALSKQLTV"
     gene            complement(7378..7803)
                     /locus_tag="VVO77_000960"
     CDS             complement(7378..7803)
                     /locus_tag="VVO77_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
                     /protein_id="HEU5692989.1"
                     /translation="MLIGIPKEIKNNENRVALTPAGVHSLVSRGHRVLIETNAGLGSG
                     FTDADYQKQGAEIVATAGEAWAAELVVKVKEPLSSEYGYLRDVLLLFTYLHMAAAPEL
                     ADAMLAAKTTGIAYETVRDNQGQLPLLVPMSEVAGRMAV"
     gene            7980..8549
                     /locus_tag="VVO77_000961"
     CDS             7980..8549
                     /locus_tag="VVO77_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU5692990.1"
                     /translation="MESIFVKLAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLVNPLGRWGIELKSNGQFIGTIDLHKIDSVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            8617..9267
                     /locus_tag="VVO77_000962"
     CDS             8617..9267
                     /locus_tag="VVO77_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HEU5692991.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     VEVAAVSKDLVSEKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD"
     gene            9251..11491
                     /locus_tag="VVO77_000963"
     CDS             9251..11491
                     /locus_tag="VVO77_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEU5692992.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCL
                     FIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQNLADSVERVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRSLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     LEVTKAFHVGEILVSKGSLKQKQFVVELQATQTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKAAQHGSKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGWNSW
                     KIESVR"
     gene            11633..11857
                     /locus_tag="VVO77_000964"
     CDS             11633..11857
                     /locus_tag="VVO77_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692993.1"
                     /translation="MIIGLFQSSISAVTVTKSYKYDWNTVWEYSTNYHDHQYAWIPSW
                     SRYYSYSEYPVGSGWNYARYEVINYYTGGY"
     gene            11889..12476
                     /locus_tag="VVO77_000965"
     CDS             11889..12476
                     /locus_tag="VVO77_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5692994.1"
                     /translation="MLRLTHVTLKTRQVILQDVDFTFKKGRVYGLLAINGSGKTTLFR
                     AISNLIPISSGNIAAPPSLFYYESIEWLDGNLSGMDYLRLIKNIWKSGLNLRDEIAYW
                     EMSDYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDVCDRVVTIHQGQIEEV"
     gene            12480..13661
                     /locus_tag="VVO77_000966"
     CDS             12480..13661
                     /locus_tag="VVO77_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5692995.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIVLALFVSVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDISSEEYQFAKNNLDVQKNLLKRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQAMYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLSKQIDNVDLNWSMGMVLLPCLIILLLVGILFIERWGSSRKKEVFK
                     V"
     misc_feature    13821..13952
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            13968..14498
                     /gene="infC"
                     /locus_tag="VVO77_000967"
     CDS             13968..14498
                     /gene="infC"
                     /locus_tag="VVO77_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEU5692996.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            14531..14731
                     /gene="rpmI"
                     /locus_tag="VVO77_000968"
     CDS             14531..14731
                     /gene="rpmI"
                     /locus_tag="VVO77_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEU5692997.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            14783..15142
                     /gene="rplT"
                     /locus_tag="VVO77_000969"
     CDS             14783..15142
                     /gene="rplT"
                     /locus_tag="VVO77_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEU5692998.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            15200..15580
                     /locus_tag="VVO77_000970"
     CDS             15200..15580
                     /locus_tag="VVO77_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU5692999.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            15830..16630
                     /locus_tag="VVO77_000971"
     CDS             15830..16630
                     /locus_tag="VVO77_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEU5693000.1"
                     /translation="MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            16593..17579
                     /locus_tag="VVO77_000972"
     CDS             16593..17579
                     /locus_tag="VVO77_000972"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEU5693001.1"
                     /translation="MVLFSAQEQLYYKEKIMTTNRLQVSLPGLDLKNPIIPASGCFGF
                     GQEYAKYYDLNLLGSIMIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAE
                     KLPWLEREYPNLPIIANVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGL
                     LIGQDPDLAYDVVKAAVEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVG
                     MRFDLKTRKPILANGTGGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEM
                     YLAGAAAIGVGTANFTNPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            17679..19787
                     /gene="lytB"
                     /locus_tag="VVO77_000973"
     CDS             17679..19787
                     /gene="lytB"
                     /locus_tag="VVO77_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEU5693002.1"
                     /translation="MKKVRFIFLALLFFLASPEGAMASDGTWQGKQYLKEDGSQAANE
                     WVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGYMAKSEWVEDKGAFYYLDQD
                     GKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKADGQHAEKEWLQIKGKDYYF
                     KSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFYIKENGNYADKEWIFENGHY
                     YYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDSHSQAWYYFKSGGYMAANEW
                     IWDKESWFYLKFDGKMAEKEWVYDSHSQAWYYFKSGGYMTANEWIWDKESWFYLKSDG
                     KIAEKEWVYDSHSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKMAEKEWVYDSHSQ
                     AWYYFKSGGYMAKNETVDGYQLGSDGKWLGGKATNKNAAYYQVVPVTANVYDSDGEKL
                     SYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFIPYYESDGHRF
                     YHYVAQNASIPVASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLTEATNYSAEEL
                     DKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHSALESNWGRSKIAKDKNNFF
                     GITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGMNVEYASDPY
                     WGEKIASVMMKINEKLGGKD"
     gene            complement(19848..21503)
                     /gene="pavA"
                     /locus_tag="VVO77_000974"
     CDS             complement(19848..21503)
                     /gene="pavA"
                     /locus_tag="VVO77_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEU5693003.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEM
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            21608..22105
                     /gene="ybeY"
                     /locus_tag="VVO77_000975"
     CDS             21608..22105
                     /gene="ybeY"
                     /locus_tag="VVO77_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEU5693004.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            22086..22481
                     /locus_tag="VVO77_000976"
     CDS             22086..22481
                     /locus_tag="VVO77_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEU5693005.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFALTGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENMVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            22498..23397
                     /gene="era"
                     /locus_tag="VVO77_000977"
     CDS             22498..23397
                     /gene="era"
                     /locus_tag="VVO77_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEU5693006.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKIPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            23446..24270
                     /gene="mutM"
                     /locus_tag="VVO77_000978"
     CDS             23446..24270
                     /gene="mutM"
                     /locus_tag="VVO77_000978"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEU5693007.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            24270..24875
                     /locus_tag="VVO77_000979"
     CDS             24270..24875
                     /locus_tag="VVO77_000979"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEU5693008.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDTQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            24862..26061
                     /locus_tag="VVO77_000980"
     CDS             24862..26061
                     /locus_tag="VVO77_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEU5693009.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSEQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            26061..26210
                     /gene="rpmG"
                     /locus_tag="VVO77_000981"
     CDS             26061..26210
                     /gene="rpmG"
                     /locus_tag="VVO77_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU5693010.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            26250..26483
                     /gene="secG"
                     /locus_tag="VVO77_000982"
     CDS             26250..26483
                     /gene="secG"
                     /locus_tag="VVO77_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEU5693011.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            26585..28939
                     /gene="rnr"
                     /locus_tag="VVO77_000983"
     CDS             26585..28939
                     /gene="rnr"
                     /locus_tag="VVO77_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEU5693012.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     AGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYLEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRDSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            28902..29369
                     /gene="smpB"
                     /locus_tag="VVO77_000984"
     CDS             28902..29369
                     /gene="smpB"
                     /locus_tag="VVO77_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEU5693013.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKRQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            29385..30245
                     /gene="tehB"
                     /locus_tag="VVO77_000985"
     CDS             29385..30245
                     /gene="tehB"
                     /locus_tag="VVO77_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HEU5693014.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMETVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            30318..31271
                     /gene="coiA"
                     /locus_tag="VVO77_000986"
     CDS             30318..31271
                     /gene="coiA"
                     /locus_tag="VVO77_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEU5693015.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIQQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            31290..33092
                     /gene="pepF"
                     /locus_tag="VVO77_000987"
     CDS             31290..33092
                     /gene="pepF"
                     /locus_tag="VVO77_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEU5693016.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYDPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYNFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            33094..33807
                     /locus_tag="VVO77_000988"
     CDS             33094..33807
                     /locus_tag="VVO77_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEU5693017.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEEFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            33874..34815
                     /gene="prsA"
                     /locus_tag="VVO77_000989"
     CDS             33874..34815
                     /gene="prsA"
                     /locus_tag="VVO77_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEU5693018.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(34932..>35016)
                     /locus_tag="VVO77_000990"
     CDS             complement(34932..>35016)
                     /locus_tag="VVO77_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEU5693019.1"
                     /translation="IDYYNNKRIKVKLKGLSPVQYRTKSFR"
BASE COUNT        10539 a         6511 c         7919 g        10047 t
ORIGIN      
        1 tattggaaag taagaaatat tgaagctgag gctattagaa gaaattgtga gcgtggtgct
       61 attttttcag gtaaaataaa atatcacgaa gattcacagt ttaaaggaga tcactatgtt
      121 gaatgttatg ctgttttaga taatacggtt atagcaagag atagaataac agtccctatc
      181 gatccgttat gtggaaaaga ttttatagag tagcatataa ttgattctta actggaatac
      241 tcactatctc tttacatcaa gaaaatgact aaacagggaa gtttgccttc ttcccttttt
      301 ttgttatact agtagaagaa aaaatagaaa gatttgtggg agtgaaaaag tcctgtggac
      361 tttttcagcc tgagccaaga aactcgaaag cttgtaagtc tgattggctt tttcaatgtg
      421 aatcttaact tcacactccc aaagaggtat tagtgtcgtg tctcaatctt atatcaatgt
      481 tatcggtgct ggtttggcag gttctgaagc agcttaccaa atcgcagagc gtggtattcc
      541 agttaaacta tatgaaatgc gtggtgtcaa gtctacaccc cagcataaaa cagacaattt
      601 tgctgagttg gtttgttcca attctttgcg tggggatgct ttgacaaatg cagttggtct
      661 tctcaaggaa gaaatgcgtc gcttgggttc tgttatcttg gaatctgctg aggctacacg
      721 tgttcctgcc ggtggagccc ttgcggtgga tcgtgatggt ttctctcaaa tggtgaccga
      781 aaaagtggtc aaccacccct tgattgaagt ggtgcgtgat gaaattacag aattgccaac
      841 agatgttatt acagttgtgg cgactggtcc cttgactagc gatgccctgg ctgaaaagat
      901 tcatgccctt aataatggcg atggcttcta tttctacgat gcagcagcgc ctattatcga
      961 tgtcaacact atcgatatga gtaaggtcta tctcaaatct cgttatgata agggagaagc
     1021 agcctatctc aatgctccaa tgaccaagca agagtttatg gatttccatg aagccttggt
     1081 caatgcggaa gaagcaccgc tcaattcttt tgaaaaagaa aagtactttg aaggatgtat
     1141 gccaatcgaa gttatggcca aacgtggcat taaaactatg ctttatggcc ctatgaagcc
     1201 agtcggtctt gagtatccgg acgactacac aggacctcgt gatggagaat ttaaaacacc
     1261 ttatgcggtt gtgcaacttc gtcaggataa tgcagctggt agcctataca atattgttgg
     1321 tttccagacc cacctcaaat ggggagaaca aaagcgtgtc ttccaaatga ttccgggtct
     1381 tgaaaatgcg gagtttgtcc gttatggtgt catgcatcgc aattcttaca tggattcacc
     1441 aaatcttctt gagcagactt accgttccaa gaaacaacca aatctcttct ttgctggtca
     1501 gatgacgggg gtggaaggct atgttgagtc ggcggcttcg ggcttagttg cgggaattaa
     1561 cgcagctcgt ctcttcaagg aagaaagcga ggttattttc cccgagacga cagcgattgg
     1621 aagcttagct cattacatta cccatgccga cagcaaacat ttccaaccaa tgaatgtcaa
     1681 ttttgggatc atcaaggagt tggaaggcga gcgtatccgt gataagaagg ctcgttatga
     1741 aaaaattgca gagcgtgccc ttgccgactt agaggaattt ttgactgtct aatttttttg
     1801 aaagaattgt tcatgatact ataaaaatct tagaaattgt gataaaatag gtaggatgaa
     1861 agaaggagag tgaaaatggc gaatcccaag tataaacgta ttttaatcaa gttatcaggt
     1921 gaagcccttg ccggtgaacg tggcgtaggg attgatatcc aaacagttca aacaatcgca
     1981 aaagagattc aagaagttca tagcttaggt atcgaaattg cccttgttat tggtggagga
     2041 aatctctggc gtggagaacc tgcagcagaa gcaggtatgg accgtgttca ggcagattac
     2101 actggaatgc ttgggactgt tatgaatgct cttgtgatgg cagattcatt gcaacaagtt
     2161 ggggttgata cgcgtgtaca aacagctatt gctatgcaac aagtggcaga gccttatgtc
     2221 cgtggacgtg cccttcgtca ccttgaaaaa ggccgtatcg ttatctttgg tgctggaatt
     2281 ggttcaccat acttctcgac agatacaaca gcggcccttc gtgcagctga aatcgaagca
     2341 gatgccatcc tcatggctaa aaatggcgtc gatggtgtgt acaatgccga tcctaagaag
     2401 gacaagacag ccgttaagtt tgaagaattg acccaccgtg atgttatcaa caaaggtctt
     2461 cgtatcatgg actcaacagc ctcaaccctc tcaatggaca acgacattga cttggttgtc
     2521 ttcaacatga accaatcagg caacatcaaa cgtgtcgtat ttggtgaaaa tatcggaaca
     2581 acagtttcaa ataatatcga agaaaaggaa taagaaagaa tatggctaac gtaattattg
     2641 aaaaagctaa agagagaatg acccagtctc accaatcact tgctcgtgaa tttggtggta
     2701 tccgtgctgg tcgtgccaat gcaagcttgc ttgaccgtgt acatgtagaa tactatggag
     2761 tcgaaactcc tcttaaccaa atcgcttcaa ttacgattcc agaagcgcgt gttttgttgg
     2821 taacaccatt tgacaagtct tcattgaaag acatcgaacg tgccttgaac gcttctgatc
     2881 ttggtatcac accggctaat gacggttctg tgattcgctt ggttatccca gctcttacag
     2941 aagaaactcg tcgtgacctt gctaaagaag tgaagaaggt cggcgaaaat gctaaagtgg
     3001 ctgtccgcaa tatccgtcgc gatgctatgg acgaagctaa gaaacaagaa aaagcaaaag
     3061 aaatcactga agacgaattg aagactcttg aaaaagacat tcaaaaagta acagacgatg
     3121 ctgttaaaca catcgacgac atgactgcta acaaagagaa agaacttttg gaagtctaaa
     3181 aataaacaga aaaactcagt tggcattgct ggctgagttt tattcgaaag aaggaaatat
     3241 gaatacaaat cttgcaagtt ttatcgttgg actgatcatc gatgaaaacg accgttttta
     3301 ctttgtgcaa aaggatggtc aaacctatgc tcttgctaag gaagaaggcc aacatacagt
     3361 aggggatacg gtcaagggtt ttgcatacac ggatatgaag caaaaactcc gcctgacaac
     3421 cttagaagtg actgccactc aggaccaatt tggttgggga cgtgtcacag aggttcgtaa
     3481 ggacttgggt gtctttgtgg atacaggcct tcctgacaag gaaatcgttg tgtcactcga
     3541 tattctccct gagctcaagg aactctggcc taagaagggc gaccaactct acatccgtct
     3601 tgaagtggat aagaaagacc gtatctgggg cctcttggct tatcaagaag acttccaacg
     3661 tcttgctcgt cctgcctaca acaacatgca gaaccaaaac tggccagcca ttgtttaccg
     3721 tctcaagctg tcaggaactt ttgtttacct accagaaaat aatatgcttg gttttattca
     3781 tcctagcgag cgttacgcag agccacgttt ggggcaagta ttagatgcgc gcgttattgg
     3841 tttccgtgaa gtggaccgca ctctgaacct ctccctcaaa ccacgctcct ttgaaatgtt
     3901 ggaaaacgat gctcagatga ttttgactta tttggaaagt aatggcggtt tcatgacctt
     3961 aaatgataag tcatctccag acgacatcaa ggcaaccttt ggcatttcta aaggtcagtt
     4021 caagaaagcc ttaggtggtc ttatgaaggc tggtaaaatc aagcaggacc agtttgggac
     4081 agagttgatt tagggaggct tatgagaaaa tcattttaca cttggctcat gaccgagcgc
     4141 aatcctaaaa gtaacagtcc caaagcaatt ttggcagacc tcgcttttga agaggcagct
     4201 tttccaaaac acacagatga ttttgatgag gtcagtcgct ttttggagga gcatgccagt
     4261 ttctctttta acctaggaga ctttgacgct atctggcaag aatacttaga acactagcat
     4321 ttattcacta ggtttgggct agtaatttct ccatccctct gctataataa aaagaaataa
     4381 aaggattaga gaggttcttt atttgaagga acattcaata gacattcaac tgagtcatcc
     4441 agatgacctg tttcatcttt ttggttccaa tgaacgccat cttcgtttga tggaagaaga
     4501 gcttgatgtt gtgattcatg ctcgtacgga gattgtccag gttttgggag aagagtctgc
     4561 ttgcgaggaa gcccgtcagg ttattcaagc tctcatggtc ttggtaaatc gtgggatgac
     4621 cgttggtacg ccagatgtag tgacggctat tagtatggtc aaaaatgatg aaattgacaa
     4681 gtttgtcgcc ctttacgaag aagaaatcat caaggataat actgggaagc ctatccgcgt
     4741 caaaacctta ggtcaaaaac tttatgtgga cagtgtcaaa cagcatgatg tgacctttgg
     4801 aattgggcca gcaggtacag ggaagacctt ccttgcagtg accttggcag tgactgccct
     4861 taaacgtggg caagtcaagc gaattatcct aactcgtcca gcggtggaag cgggagagag
     4921 tcttggattt cttccgggtg atcttaagga gaaggtggat ccttaccttc gtcctgttta
     4981 cgatgccttg tatcaaattc ttgggaaaga ccaaacgact cgtctcatgg agcgtgaaat
     5041 tatcgaaatt gcgccccttg cctatatgcg tggccggacc ttggatgatg cctttgtcat
     5101 tctcgatgag gcgcaaaaca cgaccatcat gcagatgaag atgttcttga cgcgtttagg
     5161 ctttcattct aagatgattg tcaatggaga tatcagtcag attgacctgc cacgtaatgt
     5221 caagtccggt ttgattgatg ctcaagagaa actcaagaac atccatcaga ttgactttgt
     5281 tcatttttca gccaaggatg tggttcgcca tccagttgtc gctcagatta tccgagccta
     5341 tgaatattct actgaagttg cacacgactg attttgagga agttcgcctg caaaagaata
     5401 tacttttgag agaggaaaat ccagttgtat aggctaaagg ttttatccaa aggtctgaga
     5461 caacgattag gcacgatgga aagaactttt atgtgactga tgacgatcag tgcatcttcc
     5521 tgtgtcataa tcacagggca caagaaagta ggaatttgaa aagatgattg accaactatc
     5581 taagtattac agttgtagga tactaactga aaaggatatt ccaagtattt tatctttata
     5641 tgaaagtaat cctctgtatt ttcagcattg tccaccagag ccaaattttg caactgtaaa
     5701 agaggacatg ctttgtctac ctgaaggtaa agctaaggct gataagtttt ttgttggatt
     5761 ttggaatgga tctgaccttg tggctgttat ggattttgtc tatgcatatc ctgatgagga
     5821 gactgttttt attggttttt ttatggttga tcaagcctat cagaggaaag ggattggtag
     5881 tcatattgtg acagaagcac tagcttattt tgctaagaac tttcgaaagg cacgtttggc
     5941 ttatgttaag ggaaatccgc aatctcagca tttttgggaa aagcagggct ttaaatcaat
     6001 tggatgcgag gttaagcaag aactctatac ggttgttatc gttgaacaga gcctagaaga
     6061 ttagaaatgg catcaagtaa gaactatttg gaatttgttt tggaacaatt atcaggatta
     6121 gatgatgtga cttaccgttc catgatgggg gagtatattc tttacttccg cggcaagatt
     6181 attggcggca tttatgacga tcgcttttag ttaaacccgt gcaagcagtc ttagataaga
     6241 ttgaccaatc ttcttttgag tttccataca aaggtgccaa agaaatgatt tgagtggaag
     6301 aacttgataa taagatgttt ctataagacc tgattttagc tatgtataac caactgccaa
     6361 cgcccaaacc taaaaagaaa aagcaaggtg aacgaagtaa aaaagaagtc tgctaaggcc
     6421 ctgtctttgc acgggtaaaa ttttatatat aaaaagaagc tgggactaaa gagctcagct
     6481 tcctttggtt tatataattg tcattacaag acgaagtggt tgggcgaaac tctgttgact
     6541 ttattcaatt tagagtttct tatgcacaat tgagtctgga acgaaagtct ccagttgcaa
     6601 agtatacagt acaataaacc aacgatgtaa tagctgatga cacaaagcac agtgggtagg
     6661 acttgcgaag tcaccctttt cttttcaaaa tttatactaa atcattgata tcagtgtagt
     6721 cacgattaag tccttgagca actggtaggc tagtcaagta accttgataa gtggtcacac
     6781 cttgacgcaa gccttcatct tcagagattg cttgtgcgaa tcctttgcca gccaaagctt
     6841 cgatataagg aagagtgaca ttggttaggg cgatggttga agtgcgagca accgcaccag
     6901 ggatattggc aacggcatag tggagaacac cgtgtttttc atagacgggt tcatcgtgcg
     6961 ttgtcacacg gtcagctgtt tcgataacgc caccttggtc aacagcaacg tcaacgatac
     7021 agagcctgga cgcatttgtt tgaccatctc atctgtcacc aattccggtg cttttgcacc
     7081 agggatgaga atggctccaa tcaccacatc agcatctctc atacttgctt caatgttgaa
     7141 tgaattagat ataagagttt gaatttgact tccaaagact tcttctagaa ctgagagacg
     7201 cttggcacta atatctaaaa tagtcacttg agcaccaaga ccaagggcga tgcgggcagc
     7261 atgtgtaccg acgacaccat caccgatgat agttactttt ccttttggaa cacctggtac
     7321 accaccaggt agaacaccag agccaccagc ttgcttagta aggaagtgag ctccgattta
     7381 aacagccata cgacctgcaa cctcactcat aggaacgagg agcggtagtt gtccttgatt
     7441 gtcacgaaca gtttcatagg caattcctgt tgtttttgct gctaacatag catctgctaa
     7501 ttctggagca gcggccatgt gcaagtaggt gaagagaaga agaacgtcgc gcaagtaacc
     7561 gtattcagaa cttaaaggtt cttttacttt cacaaccaac tctgctgccc aagcttcacc
     7621 agcagtagcg acaatctcag ctccttgctt ttgatagtca gcatcagtaa agccagaacc
     7681 gagaccagca tttgtttcga taaggacacg atgaccacga ctaactaagc tatgaacacc
     7741 tgcaggtgtg agggcgacac ggttttcgtt atttttaatt tcttttggga ttccgattaa
     7801 cattgagata acctaccttt caattgacgg tcttgttttg gttgtcacat tccagttcat
     7861 aaatcaaaaa tgtgacggtt tcattgtata tgaaaccgct tcaaaaatca agaaaaactt
     7921 gtcatcccaa tttttttatg ctagactagt gaaaatcaag ctctaatgga gggaaaagta
     7981 tggaatcaat ttttgtaaaa cttgcccagt atccgtctat agaaacggag cgtttattgc
     8041 ttagacctgt aactttggat gatgcggaag caatgtttga ctatgcctcg gacaagggta
     8101 atacacgtta cacttttcca accaatcaaa gcttggaaga aaccaagaat aacattgctc
     8161 agttctattt ggttaatccc ttgggacgtt ggggaataga actaaaaagc aatggtcagt
     8221 ttattggaac cattgacttg cacaagattg attctgttct taagaaggca gctattggct
     8281 acattatcaa taaaaagtat tggaatcaag gattaacgac agaagccaat cgtgctgtga
     8341 ttgagctagc ttttgagaag atagggatga ataagttgac tgcccttcac gataaggcta
     8401 atcccgcgtc aggaaaggtc atggagaaat caggcatgcg tttttcccat gcagaaccat
     8461 atgcttgtat ggaccagcat gaaaaaggcc gaatcgtgac aagagttcat tatgtcttga
     8521 ccaaggaaga ctattttgca aataaataag cagttgaaaa gaaatttttc gactgttttt
     8581 tcttcctctt acgaataatc taagagagga gaaaatatgg aagcaattat cgagaaaatc
     8641 aaagagtata aaatcatcgt catctgtact ggtctgggct tgcttgtagg cggatttttc
     8701 ctgctaaagc cagctccaca aacacctgtc aaagaaacga atttgcaggt tgaagttgca
     8761 gctgtttcca aggatttggt atccgaaaag gaagtgaaca aggaagagaa ggaagaacca
     8821 gttgaacaag atctaatcac agtagatgtc aaaggtgctg tcaaatcgcc agggatttat
     8881 gacttgcctg taggtagtcg agtcaatgat gctgttcaga aggctggtgg cttgacagag
     8941 caagcagaca gcaagtcgct caatctagct cagaaagtta gtgatgaggc tctggtttac
     9001 gttcctacta agggagaaga agcagttagt caacagactg gttcggggac agcttcttca
     9061 acaagcaagg aaaagaaggt caatctcaac aaggccagtc tggaagaact caagcaggtc
     9121 aagggactgg gaggaaaacg agctcaggac attatcgacc atcgtgaggc aaatggcaag
     9181 ttcaagtcag tagacgagct caagaaggtc tctggcattg gtggcaaaac aatagaaaag
     9241 cttaaagact atgttacagt ggattaagaa tttctctatt cccctaattt acctgagttt
     9301 tctattactt tggctttatt acgctatttt ctcagcatct tatcttgctt tgttgggctt
     9361 tgtttttctg ctagtctgtc tctttatcca atttccgtgg aaatctgctg gtaaagttct
     9421 aataatttgc ggaatctttg gattttggtt tgtttttcaa aattggcaac agagtcaagc
     9481 gagtcaaaat ctggcggatt ctgttgaaag ggtacggatt ttgcctgata ctattaaggt
     9541 taatggtgat agtctatcct ttcgtggcaa gtctaacggt cgtgctttcc aagtctatta
     9601 taaactccag tccgaggagg agaaagaagc ctttcaagct ttaaccgacc tgcatgagat
     9661 aggactagaa gggaagcttt cggagccaga agggcagaga aattttggtg gctttaatta
     9721 ccaagcctat ctgaagactc agggaattta ccagactctc aatatcaaaa caatccagtc
     9781 acttcaaaag attggcagtt gggatatagg agaaaacttg tccagtttac gtcgaaaggc
     9841 tgtggtttgg attaagacgc actttccaga ccctatgcgc aattacatga caggactctt
     9901 gctgggacat ctggacaccg actttgagga gatgaatgag ctttattcca gtctaggaat
     9961 tatccacctc tttgctctat ctggtatgca ggtaggtttt ttcatgaatg gatttaagaa
    10021 acttctcttg cgattgggct tgacccaaga aaagttgaaa tggctgactt atcccttttc
    10081 ccttatctat gcgggactaa ctggcttttc agcatcggtt attcgcagtc tcttgcaaaa
    10141 gctactggct caacatgggg ttaagggctt ggataatttt gccttgacgg tgcttgtcct
    10201 ctttattgtc atgccaaact ttttcttgac agcaggagga gtcttgtcct gcgcttatgc
    10261 ttttatcctg accatgacca gcaaagaagg ggaggggctc aaggctgtta ctagtgaaag
    10321 tctagtcatc tccttgggca tattgcccat tctatccttc tattttgcgg aatttcaacc
    10381 ttggtctatc cttttgacct ttgtcttttc ctttctattt gacttgacct tcttaccgct
    10441 cttgtctatt ttatttgtcc tttcctttct ctatccagtc attcagctga actttatctt
    10501 tgaatggttg gagggcatta ttcgcttggt gtcacaggtg acaagtagac ctctggtctt
    10561 tggacaaccc aatgcatggt ttttaatcct attgttaatt tccttggctt tggtctatga
    10621 tttgagaaaa aacattaaaa agctaacggt attgtgctta ttgattacag ggctctttct
    10681 cctgaccaag catccactgg aaaatgaaat caccatgctg gatgtggggc aaggagaaag
    10741 tattttccta cgggatgtaa ctgggaaaac cattctcata gatgtaggtg gtaaggcaga
    10801 atcttataag aaaatcgaaa aatggcaaga aaagatgacg accagcaatg cacagagaag
    10861 cttgataccc tatcttaaaa gtcgaggagt agctaagatt gaccagctga ttttgacaaa
    10921 tacggacaag gaacatgtcg gagatttgtt agaggtgacc aaggctttcc atgtagggga
    10981 gattttagta tcaaaaggca gtttgaagca gaagcaattt gtggtagaac tacaggcgac
    11041 tcaaacaaag gtgcgtagta tgacagtagg ggagaacttg cccatttttg gaagtcagtt
    11101 agaagttcta tctccaagga aaatgggaga tggaggacac gatgataccc tagttctgta
    11161 tgggaaattc ttggataagc aatttctctt cacgggaaat ttggaggaga aaggagagaa
    11221 ggacttgctg aagcactatc cagacttgaa agtaaatgtt ttgaaagctg cccaacatgg
    11281 ctctaaaaag tcatcaagtc cagcctttct agaaaaactc aaaccagagc ttactcttat
    11341 ctcagttgga aagagcaatc gaatgaaact cccccatcag gaaacattga cacgactgga
    11401 aggtatcaat agcaaagttt accgaactga ccagcaagga gctatacggt ttaaaggttg
    11461 gaatagttgg aaaatcgaaa gtgttcgata ggaaggataa atgttgtaga ttagtgaaat
    11521 aaactaaaaa tttgttgcat aataatgata aaaatggtat aatgaaaatg tattcaatac
    11581 tgaggatata aaatcattaa aaattagcaa aaatcgttta attagttagt ttatgattat
    11641 tggtcttttt cagtccagta tatctgctgt gacagtcact aaaagttaca agtatgattg
    11701 gaatacggtt tgggaatata gtaccaacta tcacgaccat cagtatgctt ggattccgtc
    11761 atggtctcgt tattacagct attctgagta tccagttggt tctggctgga actacgctcg
    11821 ttatgaggtc ataaactact atactggagg ttattaatcc ttaaagagtg agaaaaggag
    11881 ggctggatat gttaaggctt actcatgtta ccctaaaaac gcgacaagtc atcttgcaag
    11941 atgtggattt cacctttaaa aagggtaggg tttatggtct tcttgctatc aatggctctg
    12001 gaaagacgac cctgttccgt gccattagca atttaattcc cataagtagt ggaaatatcg
    12061 cagcccctcc ttctttattt tattatgaga gtattgaatg gctggatgga aacttaagtg
    12121 ggatggacta ccttcgtctt atcaaaaaca tctggaagtc aggtctgaac ttgagggatg
    12181 aaatcgccta ttgggaaatg tctgactata tcagtcttcc cattcgcaag tattccttag
    12241 gcatgaagca acgcttggtg attgccatgt atttcctcag tcaggccaaa tgctggctca
    12301 tggatgagat tacaaatggc ttagatgagt attatcgaca gaagtttttt gataggctag
    12361 cacaaatcga tagacaagaa cagctggttc ttttaagttc ccactataag gaagagttgg
    12421 ttgatgtctg cgatagagta gtaaccattc atcaggggca gatagaagag gtttagttta
    12481 tgaaagatgt tagtctattt ttattgaaaa aagttttcaa aagccgctta aactggattg
    12541 tcttagcttt atttgtatct gtactcggtg ttacctttta tttaaatagt cagactgcaa
    12601 actcacacag cttggagagc aggttggaaa gtcgcattgc agccaacgag agggctatca
    12661 atgaaaatga agagaaactc tcccaaatgt ctgatatcag ctcggaggaa taccagtttg
    12721 ctaaaaataa tttagacgtg caaaaaaatc ttttgaagcg aaagacagaa attctgactt
    12781 tattaaaaga agggcgctgg aaagaggcct actatctgca gtggcaagat gaagagaaga
    12841 attatgaatt tgtatcaaat gacccgactg ctagctctgg cttaaaaatg ggggttgacc
    12901 gcgaacggaa gatttaccaa gccatgtatc ccttgaacat aaaagcacat actttggagt
    12961 ttccgaccca cgggattgat cagattgtct ggattttaga ggttatcatc ccaagcttgt
    13021 ttgtggttgc gattattttt atgctaacac aactatttgc agaaagatat caaaatcatc
    13081 tggacacagc tcacttatat cctgtttcaa aagtgacatt tgcaatatcc tctcttggag
    13141 ttggagtggg atatgtaact gtgctgttta tcggaatctg tggcttttct tttctagtgg
    13201 gaagtctgat aagtggtttt ggacagttag attatcccta cccaatttat agcttagtga
    13261 atcaagaagt aactattggg aaaatacaag atgtattatt tcctggcttg ctcttagctt
    13321 tcttagcctt tatcgtcatt gtggaagttg tgtacttgat tgcttacttt ttcaagcaaa
    13381 aaatgcctgt cctctttctt tcactcattg ggattgttgg cttattgttt ggcatccaaa
    13441 ccattcagcc tcttcaaagg attgcacatc tgattccctt tacttacttg cgttcagtgg
    13501 agattttatc tggaagatta tctaagcaga ttgataatgt cgatctaaat tggagcatgg
    13561 ggatggtctt acttccttgc ctgattatcc ttttgttagt ggggattcta tttatcgaaa
    13621 gatggggaag ttcacgtaaa aaggaagttt ttaaagttta gttttcctat agggaagcta
    13681 aagaaaaact aacataggga gagaatcaac ttggttctct ctttttgatt cgaaaaccaa
    13741 accaaaatac aaacacaaac ttttcaaaaa ataacttttt atcttgacaa gagctagaaa
    13801 acttggtatc atataaaagt tgagaaaagc agaagtgaga gcttctcgcc ttgtgacatt
    13861 aagttgcctg gccctacgga tgaaaagttt cgaagaaacg ctatcataac gtgcgggctt
    13921 gtatatttac gagtccgcta ttgtttttct ctaataaaac aaaagaggtg aaaaccatag
    13981 caaagcaaga cttattcatc aatgatgaga ttcgtgtacg tgaagttcgc ttgattggtc
    14041 ttgagggaga acagctaggc atcaagccac tcagtgaagc gcaagctttg gctgataacg
    14101 ctaatgttga cctagtattg attcaacccc aagccaaacc gcctgttgca aaaattatgg
    14161 actacggtaa gttcaaattt gagtaccaga agaagcaaaa agaacaacgt aaaaaacaaa
    14221 gcgttgttac tgtgaaagaa gttcgtctaa gtccaacaat tgacaagggt gactttgata
    14281 caaaacttcg caatgcacgt aagttccttg aaaaaggaaa taaagttaag gtatctattc
    14341 gctttaaggg tcgtatgatt acccacaaag agattggtgc aaaagtttta gccgagtttg
    14401 ctgaagcaac tcaagatatt gccatcatcg aacaacgtgc taaaatggat ggacgtcaaa
    14461 tgttcatgca attggcgcca gcgactgaca aaaaataatt gtcagaaagt taaataaagg
    14521 agaaaaaatc atgccaaaac aaaaaacaca ccgcgcatca gctaaacgtt tcaaacgtac
    14581 aggttctggt ggacttaaac gtttccgtgc ttacacttct caccgtttcc acggaaaaac
    14641 taagaaacaa cgtcgtcatc ttcgtaaagc atctatggtg cattcaggag attacaaacg
    14701 tatcaaagca atgcttactc gcttgaaata atagcttgac tgtaagtaaa caattctagg
    14761 aaatatttgg aggaaataaa acatggcacg tgttaaaggt ggcgttgtat cacgcaaacg
    14821 tcgtaaacgt attcttaaat tagcaaaagg ttactatgga gctaaacaca tcttgttccg
    14881 tactgcaaaa gaacaagtaa tgaactctta ctactatgca taccgtgacc gtcgtcagaa
    14941 aaaacgtgac ttccgcaaat tgtggattac tcgtatcaat gcggcagctc gtatgaacgg
    15001 actttcatac tcacaattga tgcatggttt gaaattggct gagattgaag ttaaccgtaa
    15061 aatgcttgct gacttggctg ttaacgatgc agtagctttc acagctcttg cagatgcagc
    15121 taaagcaaaa cttggtaaat aacaactgat gagactggaa caggattgtc cagtcttttt
    15181 aaaaataaag gagaaagata tggcttcaaa aatgctacac acttgcttac gagtagaaaa
    15241 tcttgaaaaa tcaatcgcat tttatcaaga tgcttttggt tttaaagaat tgcgtcgcag
    15301 agattttcca gaccatgcct tcacgattgt ctatctaggt cttgagggtg atgattatga
    15361 gttggagttg acttataact acgatcacgg tccgtatgtg gttggtgatg ggtttgccca
    15421 tatcgccctc agtacacctg atcttgaggc acttcatcaa gaacacagtg caaaaggcta
    15481 tgaagtgact gagccaaatg gtctaccagg aactacacca aactattact ttgtcaaaga
    15541 ccctgatgga tataaggtcg aagtcattcg tgaaaaataa tttcgtgcaa gttaagtaga
    15601 atattcgttt tctacttgac tttttttagc tgaaagagta tactaataaa aattcaacct
    15661 ttaaggggag tccagagaga ctcacaaggt gtcagataaa agaatagtgc aattttctag
    15721 aggagacctt ttgagtgtgc tctcttgtgt tgtacgattt taactgaggc cttgcactag
    15781 caaggtcttt tctttatctg gtccccttaa aatttaagga ggaaaagtta tgaatctcac
    15841 atgtaagaag cgtttgggtg tcattcggtt ggaaaccatg aaggtggttg cacaagagga
    15901 aatcgcgcca gcaatctttg aattagtcct agaaggagaa atggttgaag ccatgcgagc
    15961 aggccaattt cttcatctgc gtgtaccaga cgatgcccat ctcttacgtc gtcctatttc
    16021 aatttcgtct attgacaagg caaacaagca gtgtcacctc atttatcgga ttgagggagc
    16081 tgggactgca attttttcaa ccttaagtca gggagacact cttgatgtga tggggcctca
    16141 gggaaatggt tttgacttgt ctgaccttga tgagcagaat caggttctcc ttgttggtgg
    16201 tgggattggt gttccaccct tgcttgaggt ggccaaggaa ttgcatgaac gtggagtgaa
    16261 agtagtgaca gtcctcggtt ttgctaataa ggatgctgtt attttgaaaa cggaattggc
    16321 tcagtatggt caggtctttg taacgacaga tgatggttct tatggcatca agggaaatgt
    16381 ttccgttgtt atcaatgatt tagatagtca gtttgatgct gtttactcgt gtggggctcc
    16441 aggaatgatg aagtatatca atcaaacctt tgatgatcac ccaagagcct atttatctct
    16501 ggaatctcgt atggcttgtg ggatgggagc ttgctatgcc tgtgttctaa aagtaccaga
    16561 aagcgagacg gtcagccaac gcgtctgtga agatggtcct gttttccgca caggaacagt
    16621 tgtattataa ggagaaaatt atgactacaa atcgattaca agtgtctcta cctggtttgg
    16681 atttgaaaaa tccgattatt ccagcatcag gctgttttgg ctttggacaa gagtatgcca
    16741 agtactatga tttaaacctt ttaggttcta ttatgatcaa ggcgacaacc cttgaaccac
    16801 gttttgggaa cccaactcca agagtagcag agacgcctgc tggtatgctc aatgcaattg
    16861 gcttgcaaaa tcctggttta gaggttgttt tggctgaaaa gctaccttgg ctggaaagag
    16921 aatatccaaa tcttcctatt attgccaatg tagctggttt ttcaaaacaa gagtatgcag
    16981 ctgtttctca tgggatttcc aaggcaacta atgtaaaagc tatcgagctc aatatttctt
    17041 gtcccaatgt tgaccactgt aatcatggac ttttgattgg tcaagatcca gatttggctt
    17101 atgatgtggt gaaagcagct gtggaagcct cagaagtgcc agtttatgtc aaattaaccc
    17161 cgagtgtgac cgatatcgtt actgtcgcaa aagctgcaga agatgcggga gcaagtggct
    17221 tgaccatgat caatactctg gttggaatgc gctttgacct caaaaccaga aaaccaatct
    17281 tggccaatgg aacaggtgga atgtcaggtc cagcagtctt tccagtagcc ctcaaactca
    17341 tccgccaagt agcccaaaca acagacctgc ctatcattgg aatgggggga gtggattcgg
    17401 ctgaagctgc cctagaaatg tatctggctg gggcagctgc tatcggagtt ggaacagcta
    17461 actttaccaa tccttatgcc tgccctgaca tcatcgaaaa tttaccaaaa gtcatggata
    17521 aatacggtat tagcagtctg gaagaactcc gtcaggaagt aaaagagtct ctgaggtaaa
    17581 ctgcaatcaa tctgttcttg attttttatt agtttgtaat atgaatttag gagaattttg
    17641 gtacaataaa tataaataag aacagaggaa gaaggttaat gaagaaagta agatttattt
    17701 ttttagctct gctatttttc ttagctagtc cagagggtgc aatggctagt gatggtactt
    17761 ggcaaggaaa acagtatctg aaagaagatg gcagtcaagc agcgaatgag tgggtttttg
    17821 atactcatta tcaatcttgg ttctatataa aagcagatgc taactatgct gaaaatgagt
    17881 ggctaaagca aggtgacgac tatttttacc tcaaatctgg tggctatatg gccaaatcag
    17941 aatgggtaga agacaaggga gccttttatt atcttgacca agatggaaag atgaaaagaa
    18001 atgcttgggt aggaacttcc tatgttggtg caacaggtgc caaagtaata gaagactggg
    18061 tctatgattc tcaatacgat gcttggtttt atatcaaagc agatggacag cacgcagaga
    18121 aagaatggct ccaaattaaa gggaaggact attatttcaa atccggtggt tatctactga
    18181 caagtcagtg gattaatcaa gcttatgtga atgctagtgg tgccaaagta cagcaaggtt
    18241 ggctttttga caaacaatac caatcttggt tttacatcaa agaaaatgga aactatgctg
    18301 ataaagaatg gattttcgag aatggtcact attattatct aaaatccggt ggctacatgg
    18361 cagccaatga atggatttgg gataaggaat cttggtttta tctcaaattt gatgggaaaa
    18421 tagctgaaaa agaatgggtc tacgattctc atagtcaagc ttggtactac ttcaaatccg
    18481 gtggctacat ggcagccaat gaatggattt gggataagga atcttggttt tacctcaagt
    18541 ttgatggcaa aatggctgaa aaagaatggg tctacgattc tcatagtcaa gcctggtact
    18601 acttcaaatc cggtggttac atgacagcca atgaatggat ttgggataag gaatcttggt
    18661 tttatctcaa atctgatggg aaaatagctg aaaaagaatg ggtctacgat tctcatagtc
    18721 aagcttggta ctacttcaaa tccggtggtt acatgacagc caatgaatgg atttgggata
    18781 aggaatcttg gttttacctc aagtctgatg gcaaaatggc tgaaaaagaa tgggtctacg
    18841 attctcatag tcaagcctgg tactacttca aatctggtgg ctacatggcg aaaaatgaga
    18901 cagtagatgg ttatcagctt ggaagcgatg gtaaatggct tggaggaaaa gctacaaata
    18961 aaaatgctgc ttactatcaa gtagtgcctg tcacagccaa tgtttatgat tcagatggtg
    19021 aaaagctttc ctatatatcg caaggtagtg tcgtatggct agataaggat agaaaaagtg
    19081 atgacaagcg cttggctatt actatttctg gtttgtcagg ctatatgaaa acagaagatt
    19141 tacaagcgct agatgctagt aaggacttta tcccttatta tgagagtgat ggccaccgtt
    19201 tttatcacta tgtggctcag aatgctagta tcccagtagc ttctcatctt tctgatatgg
    19261 aagtaggcaa gaaatattat tcggcagatg gcctgcattt tgatggtttt aagcttgaga
    19321 atcccttcct tttcaaagat ttaacagagg ctacaaacta cagtgctgaa gaattggata
    19381 aggtatttag tttgctaaac attaataata gccttttgga gaacaagggc gctactttta
    19441 aggaagccga agaacattac catatcaatg ccctttatct ccttgcccat agtgccctag
    19501 aaagtaactg gggaagaagt aaaattgcca aagataagaa taatttcttt ggcattacag
    19561 cctatgatac gaccccttac ctttctgcca agacatttga tgatgtggat aagggaattt
    19621 taggtgcaac caagtggatt aaggaaaatt atatcgatag gggaagaact ttccttggaa
    19681 acaaggcttc tggtatgaat gtggaatatg cttcagaccc ttattggggc gaaaaaattg
    19741 ctagtgtgat gatgaaaatc aatgagaagc taggtggcaa agattagtac tataagtgaa
    19801 tatgatttga gtgaatagta agttaaaaat cctgatttca agtaaaatca ggattttttc
    19861 atggatgcaa tttttttgga gtctggtgtg acgcggaggg tcttttgtcc tgtgtaagtg
    19921 acaaagccgg gttttccacc agttggttta ttgagttttt tgacttcaat catatctacc
    19981 tgcaccagat tcgacaggcg cccttgagag aagtaggcag ctaactctgc tgcgtctgtc
    20041 ttgactgcat cagatgggtc aagatttcct gagatgacaa catggcttcc aggaatgtcc
    20101 ttagcatgga accaaagttc ctccttgcgg gccattttaa aggtcaattc ctcattttga
    20161 agattgtttc gtccgacata gatgatggtt ttgccatcgc ttgctagata ttgttctagt
    20221 tttttgcgtt tctggatttt ctcccgttgt cttctgcgga taaaacctgt ttgaatcaat
    20281 tcttcacgga tttcagcgat ttcttccagt ccagcttggt tgaggacggt ttctacactt
    20341 tccagataga gaatagtggc tttggtttct tcaatcaaat cagtcaagta tttgacagct
    20401 tctttgagtt tctgataccg tttaaaatag cgttgggcat tctggttggg agtcagagcc
    20461 ttatcaagcg caatcatgat aggttggttg gtatagtagt tgtctaggat aacctggtct
    20521 tggtcgttag gcacttggtg taggaaggtt gtcagcaatt ctcctttttg acgaaattct
    20581 tcagcgttgt ctgtcgccag taactctttt tcctgttttt tgagtttgtg tcggtttttc
    20641 tgaagttcat tttcaacacg acgaatcagt tcactggcct gctgtttgac gcggtcgcgc
    20701 tcagccttat ccttatagta ggtgtccaac aaatcagaaa gatttgcaaa aggctctccc
    20761 acctgatttg caaaaggaac tggactgaag gaagtctcag tcaagcatgg cttggtttct
    20821 tgattgaaaa aatttcggaa agcggaaagt ttttcactaa ccagtatcct ttccaattca
    20881 tttgcagtat cgcgtcccag accttgaaag aggctttgaa gattttttgc tgttagttct
    20941 tgggtttgca ggatttcaaa gagcttttca tctttgatag taaaaggatt gagagattct
    21001 gtacttggcg gagcgatata ggtcgatcct ggaagtaagg tgcggtagct attttgtgaa
    21061 aaaccgacgt gtttgataac ttcgaggatt ttatgactgc ttttatcgac cagtagaata
    21121 ttactgtgtt tccccataat ttcaataatc aaggtagcct ggatatggtc tccaatctcg
    21181 tttttattgg aaactgtcat ttccacaata cggtcatttt ccacttgctc aatcgactca
    21241 atcagggccc cctgcaaata ctttctcaaa accatgataa aggtagaagg ttgggctgga
    21301 ttttcaaaag tcgtttgggt cagctgaatg cgtccaaaaa ctggatgggc agaaaggagc
    21361 aggcgatggc tttggcgatt gctgcggatt tgcaagacca actcttgttc aaaaggctga
    21421 ttgattttct ggatgcgacc attcactaat tcgcttcgca attcctcaac tatgtggtgt
    21481 aaaaaaaatc catcaaatga catcgttctc tccttgtgat tgtattccat agtattatat
    21541 caaaaaggta gaataaaatc atggaaatgt ggtataataa agccaagtaa agagaaacga
    21601 gaagcacatg tatattgaaa tggtagatga aactggtcaa gtttcaaaag aaatgttgca
    21661 acaaacccaa gaaattttgg aatttgcagc ccaaaaatta ggaaaagaag acaaggagat
    21721 ggcagtcact tttgtgacca atgagcgtag tcatgaactt aatctggagt accgtgacac
    21781 cgaccgtccg acagatgtca tcagccttga gtataaacca gaattggaaa ttgcctttga
    21841 cgaagaggat ttgcttgaaa atccagaatt ggcagagatg atgtctgagt ttgatgccta
    21901 tattggggaa ttgttcatct ctatcgataa ggctcatgag caggccgaag aatatggtca
    21961 cagctttgag cgtgagatgg gcttcttggc agtacacggc tttttacata ttaacggcta
    22021 tgatcactac actccggaag aagaagcgga gatgttcggt ttacaagaag aaattttgac
    22081 agcctatgga ctcacaagac aataaacgaa aatggaaaaa tcgtgacctg atatccagtt
    22141 tagaatttgc tttgacaggt atttttactg ctatcaagga agaacgaaat atgcgaaaac
    22201 atgcagtgac ggctctagtg gttatccttg caggttttgt ttttcaggtg tcacgaatcg
    22261 aatggctctt tctcctattg agcattttct tggtagtagc ctttgagatt atcaactctg
    22321 ctattgaaaa tatggtggat ttggccagtc actatcactt ttccatgctg gctaaaaatg
    22381 ccaaggatat ggcggctggt gcggtattag tggtttctct tttcgcagcc ttaacaggcg
    22441 cattgatttt tctcccgcga atctgggatt tattatttta aacagtaaga ggaaattatg
    22501 acatttaaat caggctttgt agccatttta ggacgtccta acgttgggaa gtcaaccttt
    22561 ttaaatcacg tcatggggca aaagattgcc atcatgagtg acaaggcgca gacaacgcgc
    22621 aacaaaatca tgggaattta cacgactgat aaggagcaaa ttgtctttat cgacacacca
    22681 gggattcaca aacctaaaac agctctcgga gatttcatgg ttgagtctgc ctacagtacc
    22741 cttcgcgaag tggacaccgt tcttttcatg gtgcctgctg atgaagcgcg tggtaagggg
    22801 gacgatatga ttatcgagcg tctcaaggct gccaagattc ctgtgatttt ggtggtgaat
    22861 aaaatcgata aggtccatcc agaccagctc ttgtctcaga ttgatgactt ccgtaatcaa
    22921 atggacttta aggaaattgt tccaatctca gcccttcagg gaaataacgt gtctcgtcta
    22981 gtggatattt tgagtgaaaa tctggatgaa ggtttccaat atttcccgtc tgatcaaatc
    23041 acagaccatc cagaacgttt cttggtttca gaaatggttc gcgagaaagt cttgcaccta
    23101 actcgtgaag agattccgca ttctgtagca gtagttgttg actctatgaa acgagacgaa
    23161 gagacagaca aggttcacat ccgtgcaacc atcatggtcg agcgcgatag ccaaaaaggg
    23221 attatcatcg gtaaaggtgg cgctatgctt aagaaaatcg gtagcatggc ccgtcgtgat
    23281 atcgaactca tgctaggaga caaggtcttc ctagaaacct gggtcaaggt caagaaaaac
    23341 tggcgcgata aaaagctaga tttggctgac tttggctata atgaaagaga atactaagta
    23401 gaggtaggct catgcctgct tcttgttttt acagaaggag gacttatgcc tgaattacct
    23461 gaggttgaaa ccgtttgtcg tggcttagaa aaattgatta tagggaagaa gatttcgagt
    23521 atagaaattc gctaccccaa gatgattaag acggatttgg aagagtttca aagggaattg
    23581 cctagtcaga ttatcgagtc aatgggacgt cgtggaaaat atttgctttt ttatctgaca
    23641 gacaaggtct tgatttccca tttgcggatg gagggcaagt atttttacta tccagaccaa
    23701 ggacctgaac gcaagcatgc ccatgttttc tttcattttg aagatggtgg cacgcttgtt
    23761 tatgaggatg ttcgcaagtt tggaaccatg gaactcttgg tgcctgacct tttagacgcc
    23821 tactttattt ctaaaaaatt aggtcctgaa ccaagcgaac aagactttga tttacaggtc
    23881 tttcaatctg cccttgccaa gtccaaaaag cctatcaaat cccatctcct agaccagacc
    23941 ttggtagctg gacttggcaa tatctatgtg gatgaggttc tctggcgagc tcaggttcat
    24001 ccagctagac cttcccagac tttgacagca gaagaagcga ctgccattca tgaccagacc
    24061 attgctgttt tgggccaggc tgttgaaaaa ggtggctcca ccattcggac ttataccaat
    24121 gcctttgggg aagatggaag catgcaggac tttcatcagg tctatgataa gactggtcaa
    24181 gaatgtgtac gctgtggtac catcattgag aaaattcaac taggcggacg tggaacccac
    24241 ttttgtccaa actgtcaaag gagggactga tgggaaaaat catcggaatc actgggggaa
    24301 ttgcctctgg taagtcaact gtgacaaatt ttctaagaca gcaaggcttt caagtagtgg
    24361 atgccgacgc agtcgtccac caactacaga aacctggtgg tcgtctgttt gaggctctag
    24421 tacagcactt tgggcaagaa atcattcttg aaaacggaga actcaatcgc cctctcctag
    24481 ctagtctcat cttttcaaat cctgaagagc aaaaatggtc taagcaaatt caaggggaga
    24541 ttatccgtga ggaactggct actttgagag aacagttggc tcagacagaa gagattttct
    24601 tcatggatat tcccctactt tttgagcagg actacagcga ttggtttgct gagacttggt
    24661 tggtctatgt ggaccgagat acccaagtag aacgcttaat gaaaagggac cagttgtcca
    24721 aggatgaagc tgagtctcgt ctggcagccc agtggccttt agaaaaaaag aaagatttgg
    24781 ccagccaggt tcttgataat aatggcaatc agaaccagct tcttaatcaa gtgcatatcc
    24841 ttcttgaggg aggtaggcaa gatgacagag attaactgga aggataatct gcgcattgcc
    24901 tggtttggta attttctgac aggagccagt atttctttgg ttgtaccttt tatgcccatc
    24961 ttcgtggaaa atctaggtgt agggagtgag caagtcgctt tttatgcagg cttagcaatt
    25021 tctgtctctg ctatttccgc ggcgctcttt tctcctattt ggggtattct tgctgacaaa
    25081 tacggccgaa aacccatgat gattcgggca ggtcttgcta tgactatcac tatgggaggc
    25141 ttggcctttg tcccaaatat ctattggtta atctttcttc gtttactaaa cggtgtattt
    25201 gcaggttttg ttcctaatgc aacggcactg atagccagtc aggttccaaa ggagaaatca
    25261 ggctctgcct taggtacttt gtctacaggc gtagttgcag gcactctaac tggtcccttt
    25321 attggtggct ttatcgcaga attatttggc attcgtacag ttttcttact ggttggtagt
    25381 tttctatttt tagctgctat tttgactatt tgctttatca aggaagattt tcaaccagta
    25441 gccaaggaaa aggctattcc aacaaaggaa ttatttacct cggttaaata tccctatctt
    25501 ttgctcaatc tctttttaac cagttttgtc atccaatttt cagctcaatc gattggccct
    25561 attttggctc tttatgtacg cgacttaggg cagacagaga atcttctttt tgtctctggt
    25621 ttgattgtgt ccagtatggg cttttccagc atgatgagtg caggagtcat gggcaagcta
    25681 ggtgacaagg tgggcaatca tcgtctcttg gttgtcgccc agttttattc agtcatcatc
    25741 tatctcctct gtgccaatgc ctctagcccc cttcaactag gactctatcg tttcctcttt
    25801 ggattgggaa ccggtgcctt gattcccggg gttaatgccc tactcagcaa aatgactccc
    25861 aaagccggca tttcgagggt ctttgccttc aatcaggtat tcttttatct gggaggtgtt
    25921 gttggtccca tggcaggttc tgcagtagca ggtcaatttg gctaccatgc tgtcttttat
    25981 gcgacgagcc tttgtgttgc ctttagttgt ctctttaacc tgattcaatt tcgaacatta
    26041 ttaaaagtaa aggaaatcta gtgcgagtaa aaattaatct caaatgctcc tcttgtggca
    26101 gtatcaatta cctaaccagt aaaaattcaa aaacccatcc agacaagatt gaggttttaa
    26161 agtattgtcc caaggaaaga aaagtaaccc tacatcttga atctaagtag attttatggt
    26221 aaaataatag ggattttaag gagtttgata tgtataacct attattaacc attttattag
    26281 tattatctgt tgtgattgtg attgcaattt tcatgcaacc aaccaaaaac caatccagca
    26341 atgtatttga tgccagttca ggtgatttgt ttgaacgcag taaagctcgc ggttttgaag
    26401 ctgtaatgca gcgtttgaca gggattttag tctttttctg gctagccatt gccttagcat
    26461 tgacggtatt atcaagtaga taagaaaata atgggcagga ctaggtcttt gcctcttttt
    26521 atttttaaag gatgtttgag aaggttttac agtaaaagaa aattaaaaaa tctagaaaga
    26581 aaatatgaaa gatagaataa aagaatattt acaagacaag ggaaaggtga ctgttaatga
    26641 tttggctcag gctttgggaa aagacagttc caaggatttt cgtgagttga ttaaaacctt
    26701 gtccttaatg gaaagaaagc accaaattcg ttttgaagaa gatggtagtc tgacattaga
    26761 aattaagaaa aaacatgaga ttaccctcaa ggggattttt catgcccata aaaatggctt
    26821 tggctttgtt agtctggaag gcgaggagga cgaccttttt gtagggaaaa atgatgtcaa
    26881 ctatgctatt gctggtgata ccgtcgaggt agtgattaag aaagtcgctg accgcaataa
    26941 gggaacagca gcagaagcca aaattattga tatcctagaa cacagtttga caacagttgt
    27001 cgggcaaatc gttctggatc aggaaaaacc taagtatgct ggctatattc gttcaaaaaa
    27061 tcagaaaatc agtcaaccga tttatgttaa gaaaccagcc ctaaaattag aaggaacaga
    27121 agttctcaaa gtctttatcg ataaataccc aagcaagaaa catgatttct ttgtcgcgag
    27181 tgttctcgat gtggtgggac actcaacgga tgtcggaatt gatgttcttg aggttttgga
    27241 atcaatggac attgtatccg agtttccaga agctgttgtt aaggaagcag aaagtgtgcc
    27301 tgatgctccg tctcaaaagg atatggaagg tcgtctggat ctaagagatg aaattacctt
    27361 taccattgac ggtgcggatg ccaaggactt ggacgatgca gtgcatatca aggctctgaa
    27421 aaatggcaat ctggagcttg gggttcacat cgcagatgtt tcttattatg tgaccgaggg
    27481 gtctgccctt gacaaggaag cccttaaccg tgcgacttct gtttacgtga cagaccgagt
    27541 ggtgccaatg cttccagaac gactatcaaa tggcatctgc tctctcaatc cccaagttga
    27601 ccgcctgacc cagtctgcta ttatggagat tgataaacat ggtcgtgtgg tcaactatac
    27661 cattacacaa acagttatca agaccagttt tcgtatgacc tatagcgatg tcaatgatat
    27721 cctagctggc gatgaagaaa agagaaaaga atatcataaa attgtaccaa gtatcgaact
    27781 catggccaag cttcatgaaa ctttagaaaa catgcgtgtg aaacgtggag ctctcaattt
    27841 tgataccaat gaagcgaaga ttttagtgga taaacaaggt aagcctgttg atatcgttct
    27901 tcggcagcgt ggtattgccg agcggatgat tgagtctttt atgttgatgg ctaatgaaac
    27961 agttgccgaa catttcagca agttggattt gccttttatc tatcgaattc acgaggagcc
    28021 taaggctgaa aaggttcaga agtttattga ttatgcttcg agttttggct tgcgcattta
    28081 tgggactgcc agtgagatta gccaggaggc acttcaagac atcatgcgtg ctgttgaggg
    28141 agaaccttat gcagatgtat tgtccatgat gcttcttcgc tctatgcagc aggctcgtta
    28201 tttggagcac aatcacggcc actatggact agctgctgac tattatactc actttaccag
    28261 tccaattcgt cgttatccag accttcttgt tcaccgtatg attcgggatt acggccgttc
    28321 taaggaaata gcagagcatt ttgaacaagt gattccagag attgcgaccc agtcttccaa
    28381 ccgtgaacgt cgtgccatag aagctgagcg tgaagtcgaa gccatgaaaa aggctgagta
    28441 tatggaagaa tacgtgggtg aagagtatga tgcagttgta tcaagtattg tcaaattcgg
    28501 tctctttgtc gaattgccaa acacagttga aggcttgatt cacatcacta atctacctga
    28561 attttatcat ttcaatgagc gtgatttgac tcttcgtgga gaaaaatcag gtatcacttt
    28621 ccgagtgggt cagcagatcc gtatccgtgt tgaaagagcg gataaaatga ctggagagat
    28681 tgatttttca ttcgtaccta gtgagtttga tgtgattgaa aaaggcttga aacagtctag
    28741 tcgtagtggc agagggcgtg attcaaatcg tcgttcggat aagaaggaag acaagagaaa
    28801 atcaggacgc tcaaatgata agcgtaagca ttcacaaaaa gacaagaaga aaaaaggaaa
    28861 gaaacctttt tacaaggaag tagctaagaa aggagccaag catggcaaag ggcgagggaa
    28921 aggtcgtcgc acaaaataaa aaggcacgcc acgactatac aatcgtagat acgctagagg
    28981 cagggatggt cctgactgga actgaaatca agagtgtacg agctgctcga attaatctca
    29041 aggatggctt tgctcaagtg aaaaatggag aagtttggct gagcaatgtt catatcgcgc
    29101 cttacgaaga gggcaatatc tggaaccagg aaccagaacg tcgtcgtaaa ctcctgctcc
    29161 ataaaaggca aattcaaaaa ttggaacaag agaccaaagg gacaggaatg accttagttc
    29221 cccttaaggt ctatataaaa gatggctacg ctaagcttct tttaggactt gccaaaggga
    29281 agcatgacta tgacaaacgg gagtctatca aacgtcgtga gcaaaatcga gatatcgcgc
    29341 gtgtgatgaa agctgttaat cagcgataaa aagaggaatt gaaaatggaa aaattagttg
    29401 cctataaacg catgcctttg tggaataaac aaacaatgcc tgaagctgtt cagcaaaagc
    29461 acaatacaaa agttgggact tgggggaaaa ttactgtctt gaagggagct ctcaagttta
    29521 ttgaattgac agaagaaggg gaagttctag ctgaacacct ctttgaagca ggggcagaca
    29581 atccaatggc ccaacctcaa gcctggcacc gagtggaagc tgccacagat gatgtggaat
    29641 ggtacttgga attttattgt aaacctgagg attattttgc taaaaaatac aataccaatc
    29701 ctgttcattc agaggtccta gaggccatgg agacagtgaa acaagggaaa gctttggatt
    29761 tgggttgtgg tcaggggcgt aattctcttt ttctagccca gcaagatttt gatgtgacgg
    29821 ctgtagatca aaatggacta gctcttgaaa tcttgcaaag cattgtggag caggaagatt
    29881 tggacatgcc tgttggcctt tacgatatca attcagctag cattgaacaa gaatatgatt
    29941 ttatcgtttc aacagttgtt ctcatgtttc tacaagcgga ccgcattcca gctattattc
    30001 aaaatatgca ggagaaaacc agtgttggtg gttacaacct tatcgtttgt gccatggaca
    30061 cggaggatta tccttgctcg gttaacttcc cattcacctt taaagaagga gaactggcag
    30121 actattacaa ggattgggaa ttggttaagt acaatgaaaa tccaggccat ttgcatcgtc
    30181 gcgatgagaa tggcaatcgt attcaactac gctttgcgac cttactagct aagaaaatca
    30241 agtaaacaca catgaagatt aggaattttc ctgatctttt ttctttttta cgaatgatat
    30301 agaaaaggag ggaattcatg tttgttgcga gagatgctag gggagaattg gtaaatgtgt
    30361 tagaggataa acttgagaag caagcataca cctgcccagc ttgtggaggc cagctccatt
    30421 tgcgtcaagg accaagtgta cggacgcatt ttgcccataa atccttaaaa gactgtgatt
    30481 ttttctttga aaatgaaagt ccagaacacc tggccaataa ggaatccctc tatcactggt
    30541 tgaaaaaaga gacaaaggtt caattagagt acccgctttc agaacttaaa cagattgcgg
    30601 atgtatttgt aaatggcaat ctagctctag aagttcagtg tagtcccttg cctcagaaag
    30661 tccttaaaga gcgaagtgag ggctatcgta gtcagggtta ccaagtactg tggttgctgg
    30721 gtcaaaaact gtggctcaag gagcgtttga ctcgtctaca gcaaggtttt ctttatttca
    30781 gtcaaaacat gggcttttat gtttgggaat tagacaagga aaaacaagtt ttaagactca
    30841 aatacctgat ttaccaggat ctccgcggta aactccatta tcaaatcaag gaattttcct
    30901 atggtcaagg tagtttattg gaaatattgc gtcttcccta taagagacaa aaaatatctc
    30961 attttacagt ttctgaggac aaggacatct gtcgctatat ccagcaacaa ctttattatc
    31021 aaaatctctt ttggatgaaa gaacaagcag aagcctatca aaagggagaa aatatcctga
    31081 cttatggact gaaagaatgg tatccacaaa ttcgaccaat agtgggcaaa tttttccaga
    31141 ttgaacaaga cttgactagc tattatcagc acttttatac ctattaccaa aaaaatcctc
    31201 aaaatgattg gcaaaagctt tatccaccag ccttttatca gcaatatttc ttgaaaaata
    31261 tggtagaata gaaaggatgg aggaatctaa tggtattaca aagaaatgaa ataaatgaaa
    31321 aagatacatg ggatctatca acgatctacc caactgacca ggcttgggaa gaagccttaa
    31381 aagatttaac agaacaattg gagacagtag cccagtatga aggccatctc ttggatagtg
    31441 cggataacct actagaaatc actgaatttt ctcttgaaat ggaacgccag atggagaagc
    31501 tttacgttta tgctcatatg aagaatgacc aggatacacg tgaagctaag tatcaagagt
    31561 actatgccaa ggccatgaca ctctacagcc agttagacca agccttttca ttctatgatc
    31621 ctgaatttat ggagattagc gaaaagcagt atgctgactt tttagaagct caaccaaagc
    31681 tgcaggttta tcaacactat tttgacaagc tcttgcaagg caaggatcac gttctttcac
    31741 aacgtgaaga agaattattg gctggagctg gagaaatctt tggttcagca agtgaaacct
    31801 tcgctatctt ggacaatgcg gatattgtgt tcccttatgt cctagacgat gatggtaaag
    31861 aagttcagct atctcatggg acttacacac gtttgatgga gtctaaaaaa cgtgaggttc
    31921 gccgtggtgc ctatcaagct ctttatgcga cttacgaaca attccaacac acctatgcca
    31981 aaaccttgca aaccaatgtt aaggtgcaaa attaccgtgc taaagttcgt aactacaaga
    32041 gtgctcgtca tgcagccctc gcagcgaatt ttgttccaga aagtgtttat gacaatttgg
    32101 tagcagcagt tcgcaagcat ttgccactct tacatcgcta tcttgagctt cgttcaaaaa
    32161 tcttggggat ttcagatctc aagatgtacg atgtctacac accgctttca tctgttgaat
    32221 acaattttac ctaccaagaa gccttgaaaa aagcagaaga tgctttggca gtcttgggtg
    32281 aggattactt gagccgtgtc aaacgtgcct tcagcgagcg ttggattgat gtttacgaaa
    32341 atcaaggcaa gcgttcaggt gcctactctg gtggttctta cgataccaat gcctttatgc
    32401 ttctcaactg gcaggacaat ctggacaatc tctttactct tgttcatgaa acaggtcaca
    32461 gtatgcattc aagctatact cgtgaaactc agccttatgt ttacggagat tactctatct
    32521 ttttggctga gattgcctca actaccaatg aaaatatctt gacggagaaa ttattggaag
    32581 aagtggaaga cgacgcaaca cgctttgcta ttctcaataa cttcctagat ggtttccgtg
    32641 gaacagtttt ccgccaaact caatttgctg agtttgaaca cgccattcac caagcagatc
    32701 aaaatgggga ggtcttgaca agcgatttcc taaataaact ctacgcagac ttgaaccaag
    32761 agtattatgg tttgagtaag gaagacaatc ctgaaatcca atacgagtgg gctcgcattc
    32821 cacacttcta ctataactac tatgtatatc aatattcaac tggctttgcg gccgcctcag
    32881 ccttggctga aaaaattgtc catggtagtc aagaagaccg tgaccgctat atcgactacc
    32941 tcaaggcagg taagtcggac tatccactta atgtcatgag aaaagctggt gttgatatgg
    33001 agaaggaaga ctacctcaac gatgcctttg cagtctttga acgccgttta aatgagtttg
    33061 aagcccttgt tgaaaaatta ggattggcat aaaatggttg aatcgtatag taagaatgct
    33121 aaccataaca tgcgtcgtcc tgtcgtcaaa gaagaaattg tagacttgat gcgtcagcgt
    33181 caaaagcagg tcacaggttt cttgaaagaa ttggaagaat ttgcccgcaa ggaaaatatt
    33241 cctattattc cccatgaaac ggttgcttat ttccgttttc ttatggaaac catgcagcct
    33301 aaaaatattc tggaaattgg gacggctatc ggtttttcag ctctcttgat ggctgaacat
    33361 gcgccaaatg ctaagattac aactattgat cgtaatccag aaatgattgg ttttgccaag
    33421 gaaaattttg cccagtttga cagtcgcaag caaatcactc tcctagaggg agatgcggtg
    33481 gatgtcttat ctacactgac agagtcttat gatttcgtct ttatggattc tgccaagtct
    33541 aaatacatcg tctttctgcc agaaatcctc aaacatttgg aagttggtgg tgtggttgtc
    33601 ttggatgata tttttcaagg tggtgatgtt gccaaggata ttatggaagt ccgtcgtggt
    33661 cagcgaacca tttatcgagg ccttcaaaaa ttatttgatg caaccttaga caatccagaa
    33721 ctcaccgcaa cattagtgcc tttaggagat ggtattctca tgcttcgtaa aaatgtagca
    33781 gatgttcaac tgtctgaaag cgaatgattt tcagaaaaat ttaagaaaaa atagtaaaat
    33841 agatagagta acacttatct caaaggagta gacatgaaga aaaaattatt ggcaggtgcc
    33901 atcacactat tatcagtagc aactttagca gcttgttcga aagggtcaga aggagcagac
    33961 cttatcagca tgaaagggga tgtcatcaca gaacatcaat tttatgagca agtgaaaaac
    34021 aacccttcag cccaacaagt cttgttaaat atgaccatcc aaaaagtttt tgaaaaacaa
    34081 tatggctcag agcttgatga taaagaggtt gatgatacta ttgccgaaga aaaaaaacaa
    34141 tatggcgaaa actaccaacg tgtcttgtca caagcaggta tgactcttga aacacgtaaa
    34201 gctcaaattc gtacaagtaa attagttgag ttggcagtta agaaggtagc agaagctgaa
    34261 ttgacagatg aagcctataa gaaagccttt gatgagtaca ctccagatgt aacggctcaa
    34321 atcatccgtc ttaataatga agataaggcc aaagaagttc tcgaaaaagc caaggcagaa
    34381 ggtgctgatt ttgctcaatt agccaaagat aattcaactg atgaaaaaac aaaagaaaat
    34441 ggtggagaaa ttacctttga ttctgcttca acagaagtac ctgagcaagt caaaaaagcc
    34501 gctttcgctt tagatgtgga tggtgtttct gatgtgatta cagcaactgg cacacaagcc
    34561 tacagtagcc aatattacat tgtaaaactc actaagaaaa cagaaaaatc atctaatatt
    34621 gatgactaca aagaaaaatt aaaaactgtt atcttgactc aaaaacaaaa tgattcaaca
    34681 tttgttcaaa gcattatcgg aaaagaattg caagcagcca atatcaaggt taaggaccaa
    34741 gccttccaaa atatctttac ccaatatatc ggtggtggag attcaagctc aagcagtagt
    34801 acatcaaacg aatagtccaa atcaatgagt cagggaaaaa aactcgactt caggaaaaaa
    34861 tgaagcaaac attcccaaaa taaaacgcat agtacaaggt ttgtactgcc cccaaaagtt
    34921 agacaattaa tttatctgaa ggatttagtt ctgtattgca cagggctaag tccttttagt
    34981 tttaccttaa ttctcttatt gttgtaataa tcaata
//
LOCUS       DAVHLA010000017        34988 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVHLA010000017 DAVHLA010000000
VERSION     DAVHLA010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34988
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.017"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            143..2125
                     /locus_tag="VVO77_000991"
     CDS             143..2125
                     /locus_tag="VVO77_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU5693020.1"
                     /translation="MKSSRLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSEEQKTSTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVVIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDETTDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            2426..7729
                     /locus_tag="VVO77_000992"
     CDS             2426..7729
                     /locus_tag="VVO77_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEU5693021.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQKGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKDDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYGNDRTVVSVKTDNQEGVKADDTPAQKETGPVVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPRAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTEKEKMYYFNTQAGTTTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRNNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKVTFLVTGAETGD
                     TWVGIYSTGNASNTRSDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVAED
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWGGGDVGKPATMVLKEATEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLVSNQGKTPDYKQEID
                     RPETPEQILPATGESQSDTALFLASVSLALSALFVVKTKKD"
     gene            complement(7896..10055)
                     /locus_tag="VVO77_000993"
     CDS             complement(7896..10055)
                     /locus_tag="VVO77_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HEU5693022.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGIYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWNSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(10052..10648)
                     /gene="recU"
                     /locus_tag="VVO77_000994"
     CDS             complement(10052..10648)
                     /gene="recU"
                     /locus_tag="VVO77_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEU5693023.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            10714..11241
                     /locus_tag="VVO77_000995"
     CDS             10714..11241
                     /locus_tag="VVO77_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEU5693024.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGTLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            11311..11640
                     /gene="gpsB"
                     /locus_tag="VVO77_000996"
     CDS             11311..11640
                     /gene="gpsB"
                     /locus_tag="VVO77_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEU5693025.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            11661..12041
                     /gene="rnpB"
                     /locus_tag="VVO77_000997"
     ncRNA           11661..12041
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VVO77_000997"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            12126..13283
                     /locus_tag="VVO77_000998"
     CDS             12126..13283
                     /locus_tag="VVO77_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEU5693026.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQIENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLCSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            13296..14690
                     /gene="mapZ"
                     /locus_tag="VVO77_000999"
     CDS             13296..14690
                     /gene="mapZ"
                     /locus_tag="VVO77_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEU5693027.1"
                     /translation="MSKKRRNRQKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLNQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNIGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            14766..16190
                     /gene="gndA"
                     /locus_tag="VVO77_001000"
     CDS             14766..16190
                     /gene="gndA"
                     /locus_tag="VVO77_001000"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEU5693028.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSHKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVYASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            16202..16891
                     /locus_tag="VVO77_001001"
     CDS             16202..16891
                     /locus_tag="VVO77_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU5693029.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVAYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESVTETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            16989..18005
                     /gene="cbpC"
                     /locus_tag="VVO77_001002"
     CDS             16989..18005
                     /gene="cbpC"
                     /locus_tag="VVO77_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HEU5693030.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGQFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEPKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDASGKML
                     TDWQKVNGKWYYFGSSGSMATGWKYVRGKWYYLDNKNGDMKTGWQYFGNKWYYLRSSG
                     AMVTGWYQDGLTWYYLNAGNGDMTTGWFQVNGRWYYAYSSGALAVNTTVDGYSVNYNG
                     EWVQ"
     gene            18127..19005
                     /gene="mvk"
                     /locus_tag="VVO77_001003"
     CDS             18127..19005
                     /gene="mvk"
                     /locus_tag="VVO77_001003"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEU5693031.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFWVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            18987..19940
                     /gene="mvaD"
                     /locus_tag="VVO77_001004"
     CDS             18987..19940
                     /gene="mvaD"
                     /locus_tag="VVO77_001004"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEU5693032.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGHRYRLIVSKTKDLSQDDCC"
     gene            19927..20934
                     /locus_tag="VVO77_001005"
     CDS             19927..20934
                     /locus_tag="VVO77_001005"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEU5693033.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKAAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            20918..21928
                     /locus_tag="VVO77_001006"
     CDS             20918..21928
                     /locus_tag="VVO77_001006"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEU5693034.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDNS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKSVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEANDQMK
                     KA"
     gene            22005..22703
                     /locus_tag="VVO77_001007"
     CDS             22005..22703
                     /locus_tag="VVO77_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEU5693035.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            22700..23695
                     /locus_tag="VVO77_001008"
     CDS             22700..23695
                     /locus_tag="VVO77_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU5693036.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FFFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVVDPDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            23709..24341
                     /locus_tag="VVO77_001009"
     CDS             23709..24341
                     /locus_tag="VVO77_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU5693037.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            24342..24583
                     /locus_tag="VVO77_001010"
                     /pseudo
     CDS             24342..24583
                     /locus_tag="VVO77_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            24565..24819
                     /locus_tag="VVO77_001011"
     CDS             24565..24819
                     /locus_tag="VVO77_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEU5693038.1"
                     /translation="MAANYLKAMQSYLKETDLPKLEQLVVTKSWWDTVDILDRVVGSL
                     VYEHSELEEIILILFENLFKPRQLYLQPQNSVLSNLRLAS"
     gene            24844..25110
                     /locus_tag="VVO77_001012"
                     /pseudo
     CDS             24844..25110
                     /locus_tag="VVO77_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            25260..25499
                     /locus_tag="VVO77_001013"
     CDS             25260..25499
                     /locus_tag="VVO77_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693039.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPESNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            25580..26401
                     /gene="cbpG"
                     /locus_tag="VVO77_001014"
     CDS             25580..26401
                     /gene="cbpG"
                     /locus_tag="VVO77_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
                     /protein_id="HEU5693040.1"
                     /translation="MNVEGRGSANFIKDNVLITAAHNYYRHDYGKEADDIYVLPAVSP
                     SQELFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLGTLGLPTSQKNLT
                     GITVTITGYPSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSGSTVYDASHRVVG
                     VHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGWKKINGSWYHYRQHDKQTGWQE
                     INDTWYYLDSSGKMLTDWQKVNGKWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            26420..27442
                     /gene="cbpF"
                     /locus_tag="VVO77_001015"
     CDS             26420..27442
                     /gene="cbpF"
                     /locus_tag="VVO77_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpF"
                     /protein_id="HEU5693041.1"
                     /translation="MKLLKKMMQIALATFFFGLLATNTVFADDSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDPLSGEMVVGWQYIPAPHKGVTIGPSPRIEIALRPDWF
                     YFGQDGVLQEFVGKQVLEAKTATNTNKHHGEEYDSQAEKRVYYFEDQRSYHTLKTGWI
                     YEEGHWYYLQKDGGFDSRINRLTVGELARGWVKDYPLTYDEEKLKAAPWYYLNPATGI
                     MQTGWQYLGNRWYYLHSSGAMATGWYKEGSTWYYLDAENGDMRTGWQNLGNKWYYLRS
                     SGAMATGWYQESSTWYYLNASNGDMKTGWFQVNGNWYYAYDSGALAINTTVGGYYLNY
                     NGEWVK"
     gene            complement(27570..28918)
                     /locus_tag="VVO77_001016"
                     /pseudo
     CDS             complement(27570..28918)
                     /locus_tag="VVO77_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            29127..30896
                     /locus_tag="VVO77_001017"
     CDS             29127..30896
                     /locus_tag="VVO77_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HEU5693042.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGAIATVGAITGSSVPMFIGA
                     MVMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLT
                     VAVGNGVEAIVNARLLPMANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHLNVLLGVLVAAVVSFLVA
                     ALILHADKSTEDSLEAAQAATQAAKAQSKGQLVSTSVDAVVSTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLASPRYDEIVASLTGAFPIAEIEGDIPTSAPVDSQEIDLNHIDAVVVAYGKAQ
                     GTATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNS
                     QFLIVDSLVTTPEYDKMAARMYK"
     gene            30920..32875
                     /locus_tag="VVO77_001018"
     CDS             30920..32875
                     /locus_tag="VVO77_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU5693043.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEITKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECTKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQAYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYTKIDFFKDKVLFNFLFHHIRLSLGVPILFQGENLPESI
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLTNQEIDVIS
                     SFPTVKELLELQERLQYVQAHRTIVARDAIAPEKSYDLQDYLISSSQLLSQFELVQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTTN
                     SFTMFELKLPISALSMKREEEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIFNEKIKKLEN"
     gene            32877..33314
                     /locus_tag="VVO77_001019"
     CDS             32877..33314
                     /locus_tag="VVO77_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU5693044.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYEGGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKKDVLKSGITVVQVPRGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLADAQSKEEVLRLFDAVE"
     gene            33376..34512
                     /locus_tag="VVO77_001020"
     CDS             33376..34512
                     /locus_tag="VVO77_001020"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HEU5693045.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKNGFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQALDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPAQSHEDSLFVVVEPFNEWVVETKRLKNPDLRLKDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHK
                     VIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIEQIVEYI"
BASE COUNT        10641 a         6230 c         7824 g        10293 t
ORIGIN      
        1 tatagttgag ggatttttaa atgatattca tattttttgc aaagatgttg tttgaaaaat
       61 aattttcaaa aattctgaaa attctgttga caactttctg aaaagagtct ataatggaga
      121 gaaagtttta aaggagaaaa tgatgaaaag ttcaagacta tttgcccttg cgggcgtgac
      181 attattggcg gcgactactt tagctgcatg ctctggatca ggttcaagca ctaaaggtga
      241 gaagacattc tcatacattt atgagacaga ccctgataac ctcaactatt tgacaactgc
      301 taaggctgcg acagcaaata ttaccagtaa cgtggttgat ggtttgctag aaaatgatcg
      361 ctacgggaac tttgtgccgt ctatggctga ggattggtct gtatccaagg atggattgac
      421 ttacacttat actatccgta aggatgcaaa atggtatact tctgaaggtg aagaatacgc
      481 ggcagtcaaa gctcaagact ttgtaacagg actaaaatat gctgctgata aaaaatcaga
      541 tgctctttac cttgttcaag aatcaatcaa agggttggat gcctatgtaa aaggggaaat
      601 caaagatttc tcacaagtag gaattaaggc tctggatgaa cagacagttc agtacacttt
      661 gaacaaacca gaaagcttct ggaattctaa gacaaccatg ggtgtgcttg cgccagttaa
      721 tgaagagttt ttgaattcaa aaggggatga ttttgccaaa gctacggatc caagtagtct
      781 cttgtataac ggtccttatt tgttgaaatc cattgtgacc aaatcttctg ttgaatttgc
      841 gaaaaatccg aactactggg ataaggacaa tgtgcatatt gacaaagtta aattgtcatt
      901 ctgggatggt caagatacca gcaaacctgc agaaaacttt aaagatggta gccttacagc
      961 agctcgtctc tatccaacaa gtgcaagttt cgcagagctt gagaagagta tgaaggacaa
     1021 tattgtctat actcaacaag actctattac gtatctagtt ggtacaaata ttgaccgtca
     1081 gtcctataaa tatacatcta agaccagtga agaacaaaaa acatctacga aaaaggctct
     1141 cttaaacaag gatttccgtc aggctattgc atttggattt gaccgtacag cctatgcctc
     1201 tcagttgaat ggacaaactg gagcaagcaa aatcttacgt aatatctttg ttccaccaac
     1261 atttgttcaa gcagatggta aaaactttgg cgatatggtc aaagagaaat tggtcactta
     1321 tggggatgaa tggaaggatg ttaatcttgc agattctcag gatggtcttt acaatccaga
     1381 aaaagccaag gctgaatttg ctaaagctaa atcagcttta caagcagaag gtgtgacttt
     1441 cccaattcat ttggatatgc cagttgacca gacagcaact acaaaagttc agcgcgtcca
     1501 atctatgaaa caatccttgg aagcaacttt aggagcggat aatgtagtca ttgatattca
     1561 acaactacaa aaagacgaag taaacaatat tacatatttt gctgaaaatg ctgctggtga
     1621 agactgggat ttatcagata atgtcggttg gggtccagac tttgccgatc catcaaccta
     1681 ccttgatatc atcaaaccat ctgtaggaga aagtactaaa acatatttag ggtttgactc
     1741 aggggaagat aatgtagctg ctaaaaaagt aggtctatat gactacgaaa aattggttac
     1801 tgaggctggt gatgagacta cagatgttgc taaacgctat gataaatacg ctgcagccca
     1861 agcttggttg acagatagtg ctttgattat tccaactaca tctcgtacag ggcgtccaat
     1921 cttgtctaag atggtaccat ttacaatacc atttgcattg tcaggaaata aaggcacaag
     1981 tgaaccagtc ttgtataaat acttggaact tcaagacaag gcagtcactg tagatgaata
     2041 ccaaaaagct caggaaaaat ggatgaaaga aaaagaagag tctaataaaa aggctcaaga
     2101 agatctcgca aaacatgtga aataactgtt gcaaaatata agaaaggatt tagtatttcc
     2161 cttgaatgct gaatcctttt ttacatttgt aaagaaagat tctaaatgta ctgaccccca
     2221 aaagttggag cctctttttg tcagaataga gaaaattttt gttaatttta cttgtttcct
     2281 attgctttct cagctattat ttgttatatt aaaagcataa ttatttttta tttatcaggg
     2341 ttaagcattg cactttcaga ggaaggagta ttttttaaaa aggaaatgta aacgcttgct
     2401 aaaaaatgaa aggatttaga agtttatgaa taaaggatta tttgaaaaac gttgtaaata
     2461 tagtattcgg aaattttcat taggtgttgc ttctgttatg attggagctg cattctttgg
     2521 gacaagtccg gttcttgcag atagcgtgca gtctggttcc acggcgaact taccagctga
     2581 tttagctact gctcttgcaa cagcaaaaga gaatgatgga cgtgattttg aagcgcctaa
     2641 ggtgggagaa gaccaaggtt ctccagaagt tacagatgga cctaagacag aagaagaact
     2701 attagcactt gaaaaagaaa aaccggctga agaaaaacca aaagaggata aacctgcagc
     2761 tgctaaacct gaaacaccta agacggtaac ccctgaatgg caaacggtag agaaaaaaga
     2821 acaaaaggga acagtcacta tccgagaaga aaaaggtgtc cgctacaacc aactatcctc
     2881 aactgctcaa aatgataacg caggaaaacc agccctgttt gaaaagaagg gcttgaccgt
     2941 tgatgccaat ggaaatgcaa ctgttgattt aaccttcaaa gatgattctg aaaagggcaa
     3001 atcacgcttt ggtgtcttcc tgaaatttaa agataccaat aataatgttt ttgtcggtta
     3061 tgacaaggat ggctggttct gggagtataa atctccaaca actagcactt ggtatagagg
     3121 tagtcgtgtt gctgctcctg aaacaggatc aacaaaccgt ctctctatca ctctcaagtc
     3181 agacggtcag ctaaatgcca gcaataacga tgtcaatctc tttgacacag tgactctacc
     3241 agctgcggtc aatgaccatc ttaaaaatga gaagaagatc cttctcaagg cgggctctta
     3301 tggcaatgac cgtacggttg tcagcgttaa aacagacaat caagaaggcg taaaagcgga
     3361 tgatactcct gcccagaaag aaacaggtcc ggttgttgac gatagcaagg tgacttatga
     3421 tacgatccag tctaaggtac ttaaggcagt aattgaccaa gccttccctc gtgtcaagga
     3481 atacagcttg aacgggcata ctttgccagg acaggtgcaa cagttcaacc aagtctttat
     3541 caataaccac cgaatcaccc ctgaagtcac ttataagaaa atcaatgaga caacagcaga
     3601 gtacttgatg aagcttcgcg atgatgctca cttaatcaat gcggaaatga cagtacgcct
     3661 gcaagttgtg gacaatcaat tgcactttga tgtgaccaag attgtcaacc acaatcaagt
     3721 cactccaggt caaaagattg atgacgaaag aaaactactt tcttctatta gtttcctcgg
     3781 caatgcttta gtctctgttt ctagtgatca aactggtgct aagtttgatg gggcaaccat
     3841 gtcaaacaat acgcatgtca gcggagatga tcatatcgat gtaaccaatc caatgaaaga
     3901 cctagccaag ggttacatgt atggatttgt ttctacagat aagcttgctg ctggtgtttg
     3961 gagtaactct caaaacagct atggtggtgg ttcgaatgac tggactcgtt tgacagctta
     4021 taaagaaaca gtcggaaatg ccaactatgt aggaatccac agctctgaat ggcaatggga
     4081 aaaagcttat aagggcattg ttttcccaga atacacgaag gaacttccaa gggctaaggt
     4141 tgttatcact gaagatgcca atgcagacaa gaaagtcgat tggcaggatg gtgccattgc
     4201 ttatcgtagc attatgaaca accctcaagg ttgggaaaaa gttaaggata tcacagctta
     4261 ccgtatcgcg atgaactttg gttctcaagc acaaaaccca ttccttatga ccttggatgg
     4321 tatcaagaaa atcaatctcc acacagatgg tcttgggcaa ggtgttctcc ttaaaggata
     4381 tggtagcgaa ggccatgact ctggtcactt gaactatgct gatattggta agcgtatcgg
     4441 tggtgtcgaa gacttcaaga ccctgattga gaaggctaag aaatatggag ctcatctagg
     4501 tatccacgtt aacgcttcag aaacttatcc tgagtctaaa tacttcaatg aaaaaattct
     4561 ccgtaagaat ccagatggaa gctatagcta tggttggaac tggctagatc aaggtatcaa
     4621 cattgatgct gcctatgacc tagctcatgg tcgtttggca cgttgggaag atttgaagaa
     4681 aaaacttggt gacggtctcg actttatcta tgtggacgtt tggggtaatg gtcaatcagg
     4741 tgataacggt gcctgggcta cccacgttct tgctaaagaa attaacaaac aaggctggcg
     4801 ctttgcgatc gagtggggcc atggtggtga gtacgactct accttccatc actgggcagc
     4861 tgacttgacc tacggtggct acaccaataa aggtatcaac agtgccatca cccgctttat
     4921 ccgtaaccac caaaaagatg cttgggtagg ggactacaga agttatggtg gtgcagccaa
     4981 ctatccactg ctaggtggct acagcatgaa agactttgaa ggctggcaag gaagaagtga
     5041 ctacaatggc tatgtgacta acctctttgc tcatgacgtc atgactaagt acttccaaca
     5101 cttcactgta agtaaatggg aaaatggtac accggtgact atgaccgata acggtagcac
     5161 ctataaatgg actccagaaa tgcgagtgga gttggtagat gctgacaata ataaagtagt
     5221 tgtaactcgt aagtcaaatg atgtcaatag cccacaatat cgcgaacgta cagtaacgct
     5281 caacggacgt gtcatccaag atggttcagc ttacttgact ccttggaact gggatgcaaa
     5341 tggtaagaaa ctttctactg agaaggaaaa gatgtactac ttcaatacgc aggccggtac
     5401 aacaacttgg acccttccaa gcgattgggc aaagagcaag gtttaccttt acaagctaac
     5461 tgaccaaggt aagacagaag agcaagaact aactgtaaaa gatggtaaaa ttaccctaga
     5521 tcttctagca aatcaaccat acgtacttta ccgttcaaaa caaaccaatc ctgaaatgtc
     5581 atggagtgaa ggcatgcaca tctatgacca aggatttaat agtggaacct tgaaacactg
     5641 gaccatttca ggcgatgctt ctaaggcaga aattgtcaag tctcaagggg caaacgatat
     5701 gcttcgtatt caaggaaaca aagaaaaagt tagtctcact cagaaattaa ctggcttgaa
     5761 accaaatacc aagtatgccg tttatgtcgg tgtcgataac cgtagtaatg ccaaggcaag
     5821 tatcactgtg aatactggtg aaaaagaagt gactacttat accaataagt ctctcgccct
     5881 caactatgta aaagcctacg cccacaatac acgtcgtaac aatgctacag ttgacgatac
     5941 aagttacttc caaaacatgt acgccttctt tacaactgga tcggacgtct caaatgttac
     6001 tctgacattg agtcgtgaag ctggtgatca agcaacttac tttgatgaaa ttcgtacctt
     6061 tgaaaacaat tcaagcatgt acggagacaa gcatgataca ggtaaaggca ccttcaagca
     6121 agactttgaa aatgttgctc agggtatctt cccatttgta gtgggtggtg ttgaaggtgt
     6181 tgaagataac cgcactcact tgtctgaaaa acacgatcca tatacacaac gtggttggaa
     6241 tggtaagaaa gtcgatgatg ttatcgaagg aaattggtca ctcaagacaa atggactagt
     6301 gagccgtcgt aacttggttt accaaactat tccgcaaaac ttccgttttg aagcaggtaa
     6361 gacctaccgt gtaacctttg aatacgaagc aggttcagac aatacctatg cttttgtagt
     6421 cggtaaggga gaattccagt caggtcgtcg tggtactcaa gcaagcaact tggaaatgca
     6481 tgaattgcca aatacttgga cagattctaa gaaagccaag aaggtaacct tccttgtgac
     6541 aggtgcagaa acaggggata cttgggtagg tatctactca actggcaatg caagtaatac
     6601 tcgtagtgat tctggtggaa atgccaactt ccgtggttat aacgacttca tgatggataa
     6661 tcttcaaatc gaagaaatta ccctaacagg taagatgttg acagaaaatg ctctgaagaa
     6721 ctacttgcca acggttgcca tgactaacta caccaaagag tctatggatg ctttgaaaga
     6781 ggcggtcttt aacctcagtc aggccgatga tgatatcagt gtggaagaag cgcgtgcaga
     6841 gattgccaag attgaagcct tgaagaatgc tttggttcag aagaaaacgg ctttggtagc
     6901 agaagacttt gcaagtctta cagctcctgc tcaggctcaa gaaggtcttg caaatgcctt
     6961 tgatggaaac ttatctagtt tatggcatac atcatggggc ggaggagatg taggcaagcc
     7021 tgcaaccatg gtcttgaaag aagcaactga aatcactgga cttcgttatg ttccacgtgg
     7081 atcaggttca aatggtaact tgcgtgatgt gaaacttgtt gtgacagatg agtctggcaa
     7141 ggagcatacc tttactgcaa ctgattggcc agataacaat aagccaaaag acattgattt
     7201 tggtaagaca attaaggcta agaaaattgt ccttacaggt actaagactt acggagatgg
     7261 tggcgataaa taccaatctg cagcggaact tatctttact cgtccacagg tagcagaaac
     7321 acctcttgac ttgtcaggct atgaagcagc tttggctaag gctcagaaat taacagacaa
     7381 agacaatcaa gaggaagtag ctagcgttca ggcaagcatg aaatatgcga cggataacca
     7441 tctcttgacg gaaagaatgg tggaatactt tgcagattat ctcaaccaat taaaagattc
     7501 tgctacgaaa ccagatgctc caactgtaga gaaacctgag tttaaactta gctctttagt
     7561 ttccaatcaa ggtaagacgc cagattataa gcaagaaata gatagaccag aaacacctga
     7621 acaaatcttg ccagcaacag gtgagagtca atctgacaca gccctcttcc tagcaagtgt
     7681 tagtctagcc ctatctgctc tctttgtagt aaaaacgaag aaagactagt atttagtaaa
     7741 acctcttaac aagattacgg aagcagtctc tatcttttcc aatgaggttt atagtacaga
     7801 aaaagcctga gaagatgtct tctcaggctt ttgttaagca cataaataca atagtgctat
     7861 gacaaaatca cccagaaaaa tctgggtgat aaatgttatg gttgtgctgg ttgaggattc
     7921 tgattttgtt gatcaggggt tgtatttgat tgttgcgtat tattgttagg attggtagtc
     7981 gtactattat ttgtgcttgg agtggttgag ctagactgtg aagttgaact atctgatgat
     8041 gagcttgaac tttcagttga tgggggttgt tgtggagcag gtgagttcca cgtagaacga
     8101 gcaccatttt taaatacgaa ttctccattt ctgtagagcc cctctggtat attccaatcc
     8161 tctggattgc ttccttcaga cagataggtc atcatagagc ggtaaacttt ggcagcgacc
     8221 gtaagaccat tgcctacaag tggtgtcaga cggttagaat agcctgtcca tacagccatt
     8281 gaatatttac gcgtatagcc agcaaatagt tcatcaggtg ctacaaattg agaggtcttg
     8341 atgtggtttt caatttcctc gtctgtatag ttagaggttc ctgttttacc agcctgaggg
     8401 agccaagcaa gataggcatt tcgtccagtt ccataactca agactgtttt catcatgtcg
     8461 gtcatcatat aggctgtcgt ttccttcatg gcacgagttc cgacattaga gaactctttt
     8521 tcactcccat cactaaagac gactttatgg atatacattg gtttatagta agttccacca
     8581 tttgcaaagg cagcgtaagc agcagccatc ttttcactac ttgctccata ttttttgtct
     8641 gattcggttg tgttacttga aatggcattt gagtagtgaa tacttgggta gtcgattccg
     8701 agaccattta ggaaagtctt ggcgcggttg agtccgacct tgtttagagt ttccacggct
     8761 gggacgtttc gcgattgttg cagggcgtat tgcaaggtga tgttgccaaa gtagccccta
     8821 tcccagttat aaacaggggt atttgtccca gggtagttat agggctcatc gtgaacgata
     8881 gtagcagttg aatcgtagat accgtactcc aaggcaggag catagtctgt gatcggtttc
     8941 atagttgatc cccagtcgcg gtttgtttct actgcttggt taattccgaa ggaaacatta
     9001 cttgactgat ggcgtgctcc tagctgggca atgactttac cgttagaaac atcaacaatg
     9061 gtagaagcga cttgcaattc atcgtctgga taggcaacgt attcgtctgt attgtaaata
     9121 tcccacagat gtttttgagc ttcttggtct acatttgtgt agacatccat cccagttgtg
     9181 agcaggttat agcctgtttc ttcttcaact tgattgatga cttccttgag gtaattatcc
     9241 atgtaagcag ggtaattact tgctgatttg agactttgta gtccatcagt aattggtgta
     9301 ttgactgctt tctcatactg ttcagcagag atgtagcctt gatttttcat ttcagataag
     9361 accaagtttc ggcggtcttg ggctgcttct ggatgtgaat aggggtcata ttggtttggt
     9421 gcctgaggca ttccagccag caaggctaac tgaggtaaac ttaaattatt gaggtcttta
     9481 ccatagtagt tttgagctgc tgtctgcatt ccatagttcc cattagacat gtagacctta
     9541 tttatatagt aggtcaagat ttcttgcttg gttgcttttt gttctaactg aatcgctaac
     9601 caagcttcct gagccttacg agaaatagtc tggtcggaag tcgaagttga aaagtaagtc
     9661 aacttaatca actgttgagt gagagttgat ccaccttgga gggaattgct ttgcagattg
     9721 cgcaagaaag ctcccaggat acggatggta tcaatccccc tgtggtcgaa gaagcgatgg
     9781 tcttcgatag aaacgattgc tttaaccaaa tctgtgggaa tatcattagc ttgggcattg
     9841 acgcggcgtt cagaacccaa gtcagcaatg agttgatttt tattgtcgta gattttacta
     9901 gaagttgttg caactagttt actctcggat aggctaggag ccttgctaac gtagtagaaa
     9961 aaaactcctc cgcctaagac aatggctgcg ataaccaagc ttaagaagct aatgctcaga
    10021 tacttgatta ggcgcagaat cgttggtttg ttcatcttgt tttaccacct aataaatgtt
    10081 ctttgataac attgagataa ggaatttgag ggaaggcacc agccttgatt tcatatccat
    10141 attctcgaat atattcaagt ggcattgatt tttgtccctt atcttgatga tagaagcgaa
    10201 tcaaatcgaa tgccggcaat aagtaggttt cttgctgaga agaaaagtga agaaggacaa
    10261 agcagattcc ttgttgggca aggacttgtt ccatatgctg aatctgatgt ggatgaaaat
    10321 ttttcatcgg aatcgcacgt ttttgttttg tttccttgac ttcaaagtcg atgtaatatc
    10381 cattataaac gccagaatag tccgtcgttg aagcttgtcg aaaataggct tcaacaatct
    10441 tggcacgact tcgttgtgga tagtccactt gtacgatttg aataggagtt ggtttcttat
    10501 gtataacagc caagccctga gacaaatagt agtcgttggt agcattgatc atcttttcaa
    10561 aagacattcc tcgatttgcg aaatttttgg gttgagaaag agatgtttgt cttttttgtg
    10621 atgaaacttt atgtggatag ttgaccataa ttctccttat tggtacaata acatcacttt
    10681 attataccat aatttgcaca gaaagggtta aaaatggcta cagctttggt tttaggctat
    10741 tctgcttttg atttgggttt attttctgat aaggatcctc gtcttaaatt gattaaaaaa
    10801 gcgatacgta aagatttaga ggctatggca gcagatgggg tgtcttggct tgtgtttaca
    10861 gggactttgg gctttgaata ttgggtttta gaggttgctc aggagatgaa aaccgaatac
    10921 ggtttccagt tggccaccat ttttgctttt gaaacccatg gggaaaattg gaatgaaggc
    10981 aatcagatga aactgagtcg ctttaagcag gtagactttg tcaaatatgc ctatcctcgc
    11041 tatgaacaca aggggcagtt aagagattac cagcagtttt tgctggaaaa cacgactagt
    11101 tcctatcttt tttatgatga agaaaatgaa acaaaactag cttattttta ccaaaagatg
    11161 aaaaatcaag aggactattt tataaagaga ttaacatttg atcaattaaa tgaacttgct
    11221 gaaaattttt ccgaaaattg aagctttgac cttgattttt gtttgccttt ttttatataa
    11281 taatactagc aagcgagaat ggagagagac atggcaagta ttattttttc agcgaaagat
    11341 atttttgaac aagagtttgg acgtgaagtc cgtggctata ataaagtaga agttgacgag
    11401 tttttagacg atgtcatcaa ggactatgaa acctatgctg ccttggtcaa gtcacttcgt
    11461 caggaaattg cggatttgaa ggaagaatta actcgtaaac cgaaaccttc accagttcaa
    11521 gcagaacccc ttgaagcggc aattacaagt tctatgacga attttgatat tttgaaacgc
    11581 ctgaatagat tggaaaaaga agtttttggt aaacaaattt tagataactc agatttttaa
    11641 gtagttattt gagatgtgca atttttggat aatcgcgtga ggagaattgc ttctcatgag
    11701 gaaagtccat gctagcacag gctgtgatgc ctgtagtgtt tgtgctaggc gaaaccataa
    11761 gcctagggac gagaaatcgt tacggcagtt gaaatggcta agtccttgga taggccagag
    11821 taggcttgaa agtgccacag tgacgaagtc tttctggaaa cagagagagt ggaacgcggt
    11881 aaacccctca agctagcaac ccaaattttg gtcggggcat ggagtacgcg gaaacgaacg
    11941 tagtattctg actgctatca gctagagctg ttagtggtag acagatgatt atcgaaggaa
    12001 gtggtcctag tcacttctgg aacaaaacat ggcttataga aaattgcata taggttgggg
    12061 ctgagaaatt ttctcaacct cattttttaa agtggacata tagaaaggtc ttgcaagact
    12121 gtaacatgaa aaaagaattt aatttaattg caactgtggc agcagggctt gaggctgtcg
    12181 ttggtcgtga agtgcgagag ttgggctacg attgtcagat tgaaaatgga cgtgttcgtt
    12241 ttcaaggaga cgtgagagct attatcgaaa ccaacctttg gctgcgggca gcagatcgta
    12301 tcaaaattat cgtaggaacg ttccctgcta agacttttga agagctattt cagggagttt
    12361 tcgctttaga ttgggaaaat tatttaccac ttggagctcg gttcccgatt tcaaaagcta
    12421 aatgtgttaa gtccaaactt cacaatgagc ccagtgttca ggctatttct aagaaagctg
    12481 ttgtcaagaa attgcagaaa cactatgctc gcccagaagg ggttcctctg atggagaatg
    12541 gcccagagtt taagattgag gtctctattc tcaaagatgt ggcaactgtc atgattgata
    12601 cgaccgggtc tagcctcttt aaacgtggtt atcgtaccga aaaaggtggc gctcctatca
    12661 aggaaaatat ggcagcagcc attttacaac tttctaactg gtatccagac aagcctttga
    12721 ttgatccgac ctgtggttcg gggactttct gtattgaggc agttatgatt gctagaaaga
    12781 tggcgccagg tcttcgtcgc tcttttgcat ttgaggaatg gaactggatc agcgatcgct
    12841 tgattcaaga agtgcgcaca gaagcggcta aaaaagtaga ccgtgagctt gagctggata
    12901 tcatgggctg tgatattgat gctcgcatgg tggaaattgc taaggccaat gctcaggcag
    12961 ctggtgttgc aggagacatt acttttaagc agatgcgcgt gcaggattta tgttccgata
    13021 aaatcaatgg agtaatcatt tccaatccgc cttatggtga acgtttgtca gatgatgcag
    13081 gggtgaccaa gctctatgct gagatggggc aagtatttgc accgctgaaa acttggagca
    13141 aatttatcct gactagtgat gaagcttttg aaagcaagta tggtagccaa gcagataaga
    13201 agcgtaagtt atacaacgga accttgaaag tggatctgta tcaatatttt ggtcagcgtg
    13261 tcaaacggca agaggtaaaa tagaaaggga tactcatgag taaaaaaaga cgaaatcgtc
    13321 aaaaaaaaga aggtcaagaa ccgcaatttg attttgatga agcaaaagag ctaacagttg
    13381 gtcaagctat tcgtaaaaat gaagaagtgg aagcaggagt cttgcctgag gattccattt
    13441 tggacaagta tgttaagcaa cacagagatg aaattgaggc ggataagttt gcgactcgtc
    13501 aatacaaaaa agaggagttc gttgaaactc agagtctgga tgatttaatt caagagatgc
    13561 gtgaggctgt agagaagtca gaagcttctt cggaggaagt tccatcttct gaagacatct
    13621 tactaccctt gcctctggac gatgaggagc aaggcttgga tcctctattg ctagatgatg
    13681 aaaatccaac agaaatgact gaagaagtgg aagaggagca aaacctttct cgtctggatc
    13741 aagaggactc agaaaagaaa agtaaaaaag gctttatttt gaccgttttg gcgcttgtat
    13801 cagtaattat ttgtgtcagt gcttattatg tctaccgtca agtggctcgt tcgaccaagg
    13861 aaattgaaac ttctcaatca actacagcca atcaatcgga tgtggatgat tttaatacac
    13921 tttatgacgc cttttacaca gatagcaata aaacggcttt gaaaaatagc cagtttgata
    13981 aactgaatca actcaagact ttacttgata agctggaagg tagtcgtgaa catacgcttg
    14041 ccaaatctaa atatgatagt ctagcaacgc aaatcaaggc tattcaagat gtcaatgctc
    14101 aatttgagaa accagctatt gtggatggtg tgttggatac caatgccaaa gccaaatcgg
    14161 atgctaaatt tacggatatt aaaactggaa atacggagct tgataaagtg ctagataagg
    14221 ctatcagtct tggtaagagc cagcaaacaa gtacttctag ctcaagttca agtcaaacta
    14281 gcagctcaag ttcaagtcaa gcaagttcaa atacgactag tgagccaaaa ccaagtagtt
    14341 caaatgagac tagaagtagt cgcagtgaag tcaatatagg tctctcgagt gcaggggttg
    14401 ctgttcaaag aagtgccagt cgtgttgcct ataatcagtc tgctattgat gatagtaata
    14461 actctgcctg ggattttgcg gatggtgtct tggaacaaat tctagcgact tcacgttcac
    14521 gtggctatat cactggagac caatatatcc ttgaacgtgt caatatcgtt aacggcaatg
    14581 gttattacaa cctctataag ccagatggaa cctatctctt tacccttaac tgtaagacag
    14641 gctactttgt cggaaatggc gctggtcatg cggatgactt ggactactaa gcagtcgtta
    14701 caaaattctt tcttttcaaa agtaaaaatg ataaaataaa acaaatgaaa caagaggagt
    14761 gtcaaatgac aaaagctaac tttggtgtcg taggtatggc cgtaatgggt cgtaaccttg
    14821 cccttaatat tgaatcacgt ggttacacag ttgctatcta caaccgtagt aaagaaaaaa
    14881 cggaagatgt gattgcttgc catcctgaaa agaattttgt accaagctat gacgttgaaa
    14941 gttttgtaaa ctcaatcgaa aaacctcgtc gtatcatgct gatggttcaa gctggacctg
    15001 gtacagatgc tactatccaa gcccttcttc cacaccttga caagggtgat atcttgattg
    15061 acggaggaaa cactttctac aaagatacca tccgtcgtaa tgaagaattg gcaaactcag
    15121 gtatcaactt tatcggtact ggagtttctg gtggtgaaaa aggtgccctt gaaggtcctt
    15181 ctatcatgcc tggtggacaa aaagaggcct acgaattggt tgcggatgtt cttgaagaaa
    15241 tctcagctaa agcaccagaa gatggcaaac catgtgtgac ttacatcggc cctgatggag
    15301 ctggtcacta tgtgaaaatg gttcacaatg gtattgagta cggtgatatg caattgatcg
    15361 cagaaagcta tgacttgatg caacacttgc taggcctttc tgcagaggat atggctgaaa
    15421 tctttactga gtggaacaag ggtgaattag acagctattt gatcgaaatc acagctgata
    15481 tcttgagcca taaagacgat gaaggccaag atggaccaat cgtagactac atccttgatg
    15541 ctgcaggtaa caagggaact ggtaaatgga ctagccaatc atctcttgac cttggtgtac
    15601 cattgtcact gattactgag tcagtgtttg cacgctacat ttcaacttac aaagaagaac
    15661 gtgtatatgc tagcaaggtg cttccaaaac cagctgcctt caactttgaa ggagacaagg
    15721 ctgaattgat tgaaaagatc cgtcaagccc tttacttctc aaaaatcatt tcatacgcac
    15781 aaggatttgc tcaattgcgt gtagcctcta aagaaaacaa ctggaacttg ccatttgcag
    15841 atatcgcatc tatctggcgt gatggctgta tcatccgttc tcgtttcttg caaaagatta
    15901 cagatgctta caaccgcgat gcagatcttg ccaaccttct tttggacgag tacttcttgg
    15961 atgttactgc taagtatcaa caagcagtgc gtgatatcgt agctcttgcg gttcaagctg
    16021 gtgtgccagt gccaactttc tcagcagcta ttacttactt tgatagctac cgttcagctg
    16081 accttccagc taacttgatc caagcacaac gtgactactt tggtgctcac acttaccaac
    16141 gtaaagacaa agaaggaacc ttccactact cttggtatga cgaaaaataa gtaggtcagc
    16201 catggggaaa cggattttat tacttgagaa agaacgaaat ctagctcatt ttttaagttt
    16261 ggaactccag aaagagcagt atcgggttga tctggtagag gaggggcaaa aagccctctc
    16321 catggctctt cagacagact atgatttgat gttattgaac gttaatctgg gagatatgat
    16381 ggctcaggat tttgcagaaa aattgagtcg aactaaacct gcctcagtca tcatgatttt
    16441 agatcattgg gaagacttgc aagaagagct ggaagttgtt cagcgttttg cagttgcata
    16501 catttataag ccagtcctta tcgaaaatct ggtagcgcgt atttcggcga tcttccgagg
    16561 tcgggacttc attgatcaac actgcagtct gatgaaagtt ccaaggactt accgcaatct
    16621 taggatagat gttgaacatc acacggttta tcgtggtgaa gagatgattg ctctgacccg
    16681 ccgtgagtat gaccttttgg cgacacttat gggaagcaag aaagtattga ctcgtgagca
    16741 attgttggaa agtgtttgga agtatgaaag tgtgaccgag acaaatatcg tagatgtcta
    16801 tatccgctat ctacggagca agcttgatgt taaaggccaa aaaagctaca ttaaaaccgt
    16861 gcgtggtgtt ggatatacca tgcaagaata gataagcagt tgcagttgtg taactgcttt
    16921 tttgaggagt ttttatatat tgacatgcag tcgggtcttt gctacaatcg ttttaggagg
    16981 atatatagat gaaacttttg aaaaaaatga tgcaagttct actagcagtc tttttctttg
    17041 gtttgctagc tacaaatacg gtatttgcga ataccacagg tggccaattt gttgataagg
    17101 ataatagaaa atattatgta aaagatgatc ataaagcaat ctattggcat aaaatagacg
    17161 gtaaaactta ctattttggt gatattggag agatggttgt cggttggcaa tacttagaaa
    17221 ttcctggaac aggttatcgt gataatttat tcgataacca accagttaat gagattggcc
    17281 ttcaggagaa gtggtactat tttggacaag atggtgcttt gctagaacaa acagataaac
    17341 aagtactaga gccaaaaacg tctgaaaata caggaaaagt atacggtgaa caatatcctc
    17401 tatctgctga aaagagaact tattattttg ataataatta tgctgtaaag acaggctgga
    17461 tttatgaaga cggcaattgg tattatttaa ataagctagg aaattttggc gatgattctt
    17521 acaatccact accaattggt gaagttgcta agggttggac tcaagatttt catgttacta
    17581 ttgacattga tagaagcaaa cctgctccat ggtactacct agatgcttca ggtaagatgc
    17641 ttacagattg gcaaaaagta aacggaaaat ggtattattt tggctcctct ggttctatgg
    17701 caacaggttg gaaatatgta cgaggcaaat ggtattactt agataataaa aatggtgata
    17761 tgaaaacagg atggcaatac tttggtaaca agtggtacta cctccgttca tcaggagcta
    17821 tggtaactgg ctggtatcaa gatggtttaa cttggtacta cctaaatgca ggtaatggag
    17881 acatgacgac aggttggttc caggtcaatg gcagatggta ctacgcttat agctcaggtg
    17941 ccttggcagt gaatacgacc gtagatggct attctgtcaa ctataatggc gaatgggttc
    18001 aataatgaaa gaagcgattg tgaatggaaa caatcgcttt ttttgtgaaa atataataaa
    18061 atagatagga aagaattaat acttgtatga aaaataagac gttttttcgt ctagtaaaag
    18121 gaaaaaatga caaaaaaagt tggtgtcggt caggcacata gtaagataat tttaataggg
    18181 gaacatgcgg tcgtttacgg ttatcctgcc atttccctgc ctcttttgga ggtggaggtg
    18241 acctgtaagg tagttcctgc agagagtcct tggcgccttt atgaggagga taccttgtcc
    18301 atggcggttt atgcctcact ggagtatttg aatatcacag aagcctgcat tcgttgtgag
    18361 attgactcgg ctatccctga gaaacggggg atgggttcgt cagcggctat cagcatagcg
    18421 gccattcgtg cagtatttga ctactatcag gctgatctgc ctcatgatgt actagaaatc
    18481 ttggtcaatc gagctgaaat gattgcccat atgaatccta gtggtttgga tgctaagacc
    18541 tgtcttagtg accaacctat tcgctttatc aagaacgtag gatttacaga acttgagatg
    18601 gatttatccg cctatttggt gattgccgat acgggtgttt atggtcatac tcgtgaagcc
    18661 atccaagtgg ttcaaaataa gggcaaggat gccctaccgt ttttgcatgc cttgggagaa
    18721 ttaacccagc aagcagaagt tgcgatttca caaaaagatg ctgaaggact gggacaaatc
    18781 ctcagtcaag cgcatttaca tttaaaagaa attggagtca gtagccctga ggcagacttt
    18841 tgggttgaaa cgactcttag ccatggtgct ctgggtgcca agatgagcgg tggtgggcta
    18901 ggaggttgta tcatagcctt ggtaaccaat ttgacacacg cacaagaact agcagaaaga
    18961 ttagaagaga aaggagctgt tcagacatgg atagagagcc tgtaacagta cgttcctacg
    19021 caaatattgc tattatcaaa tattggggaa agaaaaaaga aaaagagatg gtgcctgcta
    19081 ctagcagtat ttctctaact ttggaaaata tgtatacaga gacgaccttg tcgcctttac
    19141 cagccaatgt aacagctgac gaattttaca tcaatggtca gctacaaaat gaggtcgagc
    19201 atgccaagat gagtaagatt attgaccgtt atcgtccagc tggtgagggc tttgtccgta
    19261 tcgatactca aaacaatatg cctacggcag cgggtctgtc ctcaagttct agtggtttgt
    19321 ccgccctggt caaggcttgt aatgcttatt tcaagcttgg attggataga agtcagttgg
    19381 cacaggaagc caaatttgcc tcaggttctt cttctcggag tttttatgga ccactaggag
    19441 cctgggataa ggatagtgga gaaatttacc ctgtagagac agacttgaaa ctagctatga
    19501 ttatgttggt gctagaggac aagaaaaaac caatctctag ccgtgacggg atgaaacttt
    19561 gtgtggaaac ctcgacgact tttgacgact gggttcgtca gtctgagaag gactatcagg
    19621 atatgctgat ttatctcaag gaaaatgatt ttgccaagat tggagaatta acggagaaaa
    19681 atgccctggc tatgcatgct acgacaaaga ctgctagtcc agccttttct tatctgacgg
    19741 atgcctctta tgaggctatg gactttgttc gccagcttcg tgagaaagga gaggcctgct
    19801 actttaccat ggatgctggt cccaatgtta aggtcttctg tcaggagaaa gacttggagc
    19861 atttatcaga aattttcggt catcgttatc gcttgattgt gtcaaaaaca aaggatttga
    19921 gtcaagatga ttgctgttaa aacttgcgga aaactctatt gggcaggtga atatgctatt
    19981 ttagagccag ggcagttagc tttgataaag gatattccca tctatatgag ggctgagatt
    20041 gctttttctg acagctaccg tatctattca gatatgtttg atttcgcagt ggacttaagg
    20101 cctaatcctg actacagctt gattcaagaa acgattgctt tgatgggaga cttcctcgct
    20161 gttcgcggtc agaatttaag acctttttcc ctaaaaatct gtggcaaaat ggaacgagaa
    20221 gggaaaaagt ttggtctagg ttctagtggc agcgtcgttg tcttggttgt caaggcttta
    20281 ttggctctct ataatctttc ggttgatcag gagctcttgt tcaagctgac tagcgctgtc
    20341 ttgcttaagc gaggagacaa tggttccatg ggcgaccttg cctgtattgt ggcagaggat
    20401 ttggttctct accagtcatt tgatcgccag aaggcggctg cttggttaga agaagaaaac
    20461 ttggcgacag ttctggagcg tgattgggga ttttttatct cacaagtgaa accaacttta
    20521 gaatgtgatt tcttagtggg atggaccaag gaagtggctg tatcgagtca catggtccag
    20581 caaatcaagc aaaatatcaa tcaaaatttt ttaagttcct caaaagaaac ggtggtttct
    20641 ttggtcgaag ccttggagca ggggaaagcc gaaaaagtta tcgagcaagt agaagtagcc
    20701 agcaagcttt tagaaggctt gagtacagat atttacacgc ctttgcttag acagttgaaa
    20761 gaagccagtc aagatttgca ggccgttgcc aagagtagtg gtgctggtgg tggtgactgt
    20821 ggcatcgccc tgagttttga tgcgcaatca accaaaacct taaaaaatcg ttgggccgat
    20881 ctggggattg agctcttata tcaagaaagg ataggacatg acgacaaatc gtaaggacga
    20941 gcatatcctc tatgcccttg agcagaaaag ttcctataat agctttgatg aggtggagct
    21001 gattcattct tccttgcctc tttacaatct ggatgaaatc gatctttcga cagagtttgc
    21061 tggtcgaaag tgggactttc ctttttatat caatgccatg actggtggaa gtaataaggg
    21121 aagagaaatc aatcaaaagc tggctcaggt ggcggaatcc tgtggtattt tatttgtaac
    21181 gggttcttat agcgcagccc tcaaaaatcc aacggataat tctttttctg tcaagtctag
    21241 tcatcccaat ctcctccttg gaaccaatat tggattggac aaacctgtcg agttaggact
    21301 tcagactgta gaagagatga atcctgttct attgcaagtg catgtcaatg tcatgcagga
    21361 attactcatg cccgagggag aaaggaagtt tagaagctgg caatcgcatc tagcagatta
    21421 tagcaagcaa attcccgttc ctattgtcct caaggaagtg ggctttggaa tggatgccaa
    21481 gacaatcgaa agagcctatg aattcggtgt tcgtacagtg gacctatcgg gtcgtggtgg
    21541 caccagcttt gcctatatcg aaaaccgtcg tagtggccag cgtgattacc tcaatcaatg
    21601 gggtcagtct accatgcagg cccttctcaa tgcccaagaa tggaaagata aggtcgaact
    21661 cttggttagt ggaggggttc ggaatccgct ggatatgatt aagtgcttgg tttttggtgc
    21721 taagtctgtg ggattgtcac gaaccgttct ggaattggtt gaaacctaca cagttgaaga
    21781 agtgattggc attgtccaag gctggaaagc agacctacgc ttgattatgt gttcccttaa
    21841 ctgtgccacc atagcagatc tacaaaaagt agactatctt ctttatggaa aattaaaaga
    21901 agcaaatgat cagatgaaaa aggcgtaacc agcgcctttt ttccatcctc agactgaggt
    21961 gacttttttg aattgtgata aaatagaagg gagaggatga acctatgaga aaatttaaaa
    22021 tctttttatt tatcgaagcc tgtcttctga caggagctct gattttgatg gtatcagagc
    22081 atttttcgcg ttttctgctg atactattcc tctttttgct tttgattcgc tactacactg
    22141 gtaaagaggg gaataatctt cttttagtag cggcaaccat tctcttcttt ttcattgtta
    22201 tgctcaatcc ttttgtgatt ctagctattt ttgttgcggt tatctatagt ctctttcttc
    22261 tttacccgat gatgaaccag gaaaaagagc agaccaattt ggtttttgaa gaggttgtga
    22321 cggttaagaa ggagaaaaat cgttggtttg gaaatcttca tcatttttca agctaccaga
    22381 cttgccaatt tgatgatatc aatctctttc gcttcatggg caaggacact attcatctgg
    22441 agagagtcat cttaaccaat catgacaatg tcattatcct cagaaagatg gtaggaacga
    22501 ccaaaatcat cgtacctgta gatgtggaag tcagtctcag cgttaactgt ctctatgggg
    22561 atttgacttt tttcaaccag cccaagcgag ccctccgcaa tgaacactat catcaagaaa
    22621 caaaagacta tctcaagagt aacaagagtg tcaagatttt cttgaccact atgattggtg
    22681 atgttgaggt ggttagagga tgaaaaaaca agcctatgtc attatcgctc tcacctcctt
    22741 cctgtttgtc ttttttttct cccatagctt gctggaaata cttgattttg actggtctat
    22801 ctttttgcac gatgtcgaaa aaacagaaaa atttttcttt ttattgttgg ttttcagcat
    22861 gtccatgacc tgtctcttag ccctgttttg gcgagggatc gaagagcttt ctctaagaaa
    22921 aatgcaggct aatctcaagc gtttattggc agggcaagaa gtggttcagg ttgtagatcc
    22981 agatttggat gccagtttca agtccttatc aggtaaactt aaccttttga cagaggctct
    23041 tcaaaaagct gaaaatcata gccttgctca ggaagaggaa atcatcgaga aggaacggaa
    23101 gcgaattgct cgggatttgc acgatacagt cagtcaggag ttgtttgcgg cccacatgat
    23161 tttatcgggt atcagtcagc aggctttgaa attggataga gaaaagatgc agacccagtt
    23221 gcagagtgtc acagctattt tagaaacagc ccagaaggat ttgcgggttt tgctcttgca
    23281 tttgcgacca gttgaactgg agcagaagag cttgatagaa gggattcaaa ttcttttaaa
    23341 agagcttgag gacaagagtg atcttagggt tagtctcaag cagaatatga cgaaattgcc
    23401 taagaaaatc gaggagcata tcttccgtat cctgcaagag ttgattagca ataccctccg
    23461 ccatgcccag gcatcttgcc tagatgtcta cctctatcag acagatgttg aattgcaact
    23521 gaaggtggtg gacaatggga ttggtttcca gttagggagc ttagacgact tgagttatgg
    23581 actgcgaaat atcaaggagc gggttgaaga tatggctgga acagttcaac tcttgacagc
    23641 tcccaagcaa gggctggcgg ttgatatccg tattcctctg ttagataagg aatgataaag
    23701 gagtaaagat gaaaatttta ctagtagatg accatgaaat ggtccgattg ggcttgaaaa
    23761 gctactttga cctccaagac gatgtagaag ttgtgggtga ggcgtccaac gggtctcaag
    23821 ggattgactt ggccttggaa ctgcgtccag atgtcattgt catggatatt gtcatgcctg
    23881 agatgaatgg gattgacgcg accttagcaa tccttaaaga atggcctgaa gccaagattt
    23941 tgattgtgac ctcttatttg gacaatgaaa aaatcatgcc agtcttagat gctggtgcca
    24001 aaggctatat gctcaagact tctagtgcag atgaattgct tcatgccgtc agtaaggtag
    24061 ctgctggcga gctggccatt gagcaagagg ttagcaagaa ggttgaatac caccgcaatc
    24121 atatggaact tcatgaagaa ttgactgcgc gtgagcgaga tgttctccaa ctcatcgcca
    24181 agggctacga aaatcagcgc atcgcagatg acctctttat ctctctcaag acggtcaaga
    24241 cccacgtgtc caatattctt gccaaacttg aagtcagcga tcgtacccag gcggctgtct
    24301 atgcctttca gcaccatttg gtggggcaag aggagtttta gatgagttta gcagatttac
    24361 ttgaggagct agaagcagca aaagactcta aaaaagcaag gtccatggaa gcctatatgc
    24421 gccatcaatt ttcttttcta ggtattgcgg tgcctgaaag aaataaactc tataaaatat
    24481 tttccagaag cgaaaaaaac aaagattatc gattgggatt ttgcagacac ttgctgggaa
    24541 aagaatccta gaaaatacca atatgtggct gctaactatt tgaaagcaat gcagtcttat
    24601 ctaaaggaaa ccgatttgcc taagctagag cagttagtcg tgacaaaatc ctggtgggac
    24661 acggtagata tcctagatcg agtagtaggg agtttggtgt atgaacactc tgaactagaa
    24721 gaaataatct taatactctt cgaaaatctc ttcaaaccac gtcagctcta tctgcaacct
    24781 caaaacagtg ttttgagcaa tctgcggcta gcttcctagt ttgctctttg attttcattg
    24841 agtataaaat ggagcctatc agataatatc tggctgagac gtgtcgctat tgaccaccag
    24901 ttgttaagaa aagagaagac caatactcaa ttaatggaaa agattctact tcataacttg
    24961 aaccaaacag aattttttat caataaagcc attggctgga ctctgcgaga ctactccaaa
    25021 acgaatccca cttgggtaac atgctttatt gagaaaaaca aggaaagaat ggctgaactt
    25081 agtatcaaag aagcaagcaa gtacctctag cgtgattgaa aagcgcagtc attaattgaa
    25141 aagtttacct gtttatgtga taatggaggg tatttaaaga aggtggtaga tttcttgatt
    25201 ctatagtaga ttaagaaatt tagaatagta cgctataatt acattaggag gatacaataa
    25261 tgaagaaaac tgtttataaa aaattgggta tttcaattat tgcgagtact ttattggcta
    25321 gccagttatc gacagtatct gctttgagtg ttatttctag tacaggtgaa gaatatgagg
    25381 taagtgagac actagaaaaa ggtccagagt ctaatgattc ttcattatct gagatttcac
    25441 caacgtatgg ttcatactac caaaagcaat cagaagtatt atcggtaatg atgatttgat
    25501 taaaattgat aatactttac agtatccgta ttcgacttca gctatggttt tatctaagta
    25561 ttatggagta gccgatggaa tgaatgtaga agggagggga agtgcgaatt ttattaaaga
    25621 taatgtgtta attacagcgg ctcacaacta ctacagacat gactatggga aagaagcgga
    25681 tgatatttat gttcttccgg ctgttagtcc aagtcaagaa ctatttggaa agatcaaagt
    25741 aaaggaagtt cgttatttga aggaatttag aaatttaaat tctaaggatg caagggaata
    25801 tgacttggct ttattaattc tagaagagcc cattggtgca aaattaggga ctttgggtct
    25861 tcctactagt caaaaaaatt tgacaggaat aactgtgact atcacaggct atccatcata
    25921 taattttaaa attcatcaaa tgtatacaga taaaaaacaa gttttaagtg atgatggcat
    25981 gttcttggat taccaagttg atactttaga ggggtctagt ggatctacag tttatgatgc
    26041 tagtcaccgt gtagtaggag tgcatacttt aggagatgga gctaatcaaa ttaacagtgc
    26101 agttaaatta aatgaacgaa atttgccatt tatttattcg gttcttaaag gttactctct
    26161 tgaaggatgg aagaaaataa atggtagttg gtaccattat agacaacatg ataaacaaac
    26221 gggttggcag gagataaatg atacttggta ttatttagac agttccggta agatgcttac
    26281 agattggcaa aaagtaaatg gaaaatggta ttatctcaat tcaaatggag caatggttac
    26341 aggtagccaa actatcgatg gtaaagttta taacttcgct tcatctggtg agtggattta
    26401 atgttggagg atatataaaa tgaagctttt gaaaaaaatg atgcaaatcg cactagccac
    26461 atttttcttc ggtttgttag cgacaaatac agtatttgca gatgattctg aaggatggca
    26521 gtttgtccaa gaaaatggta gaacctacta caaaaagggg gatctaaaag aaacctactg
    26581 gagagtgata gatgggaagt actattattt tgatccttta tccggagaga tggttgtcgg
    26641 ctggcaatat atacctgctc cacacaaggg ggttacgatt ggtccttctc caagaataga
    26701 gattgctctt agaccagatt ggttttattt tggtcaagat ggtgtattac aagaatttgt
    26761 tggcaagcaa gttttagaag caaaaactgc tacgaatacc aacaaacatc atggggaaga
    26821 atatgatagc caagcagaga aacgagtcta ttattttgaa gatcagcgta gttatcatac
    26881 tttaaaaact ggttggattt atgaagaggg tcattggtat tatttacaga aggatggtgg
    26941 ctttgattcg cgcatcaaca gattgacggt tggagagcta gcacgtggtt gggttaagga
    27001 ttaccctctt acgtatgatg aagagaagct aaaagcagct ccatggtact atctaaatcc
    27061 agcaactggc attatgcaaa caggttggca atatctaggt aatagatggt actacctcca
    27121 ttcgtcagga gctatggcaa ctggctggta taaggaaggc tcaacttggt actatctaga
    27181 tgctgaaaat ggtgatatga gaactggctg gcaaaacctt gggaacaaat ggtactatct
    27241 ccgttcatca ggagctatgg caactggttg gtatcaggaa agttcgactt ggtactatct
    27301 aaatgcaagt aatggagata tgaaaacagg ctggttccaa gtcaatggta actggtacta
    27361 tgcctatgat tcaggtgctt tagctattaa taccacagta ggtggttact atttaaacta
    27421 taatggtgaa tgggttaagt aatgaagact aattgtaaac tgtgatggat acttaacttt
    27481 gtataatagg tggataaaag tcttcacaat caaaaaacgc atagtatcaa ggtttttctg
    27541 tactgccccc caaaagttag acaaataatt tatccgaagg atttagttct gtattgcaca
    27601 gggctaagtc cttttagttt taccttaatt cgtttattgt tgtagtaatc aatatagtct
    27661 acaatagctt gttccaattg attaagtgat ttaaatgttt tctcatagcc ataaaacatt
    27721 tccgatttca gaatcccaaa gaaggactcc atcataccgt tgtcttggct gtttcccttg
    27781 cgtgacatgg atgcttgaat tcccttaccc tcaagaaact gatgataaga atcgtgttga
    27841 tattgccagc cttggtcact atggagaatc gtattctcgt agtgcttctc tgtgaatgcc
    27901 tgttccaaca ttgtttgtac ttgttctaag ttgggtgaag ttgaaagatt ataggcgata
    27961 atttcgctat taaagccatc taaaactggt gataagtaaa gcttttgagt acttgctgga
    28021 atggcaaatt ctgtcacatc tgtgtagcac ttttccattg ttttagagcc ttcaaattgg
    28081 ccttgaatga gattctctgc cttcttgcca acgtctcctt tatgagaaga atattttcgt
    28141 ttctgtcgca ttttagcttg taaattgagt acttttatca agccttgaac tcttttatga
    28201 tttaccagat aaccacgatt tcttagttct aaataaattc gacgataagc ataatttccc
    28261 ttgtgttcga taaaaatgga ttgaatttca gctttaagct cttggtcctt atctgttttg
    28321 tctagctgtt tcaagtgata gtagtaggtc gaacgagcta gtttaatgga ttttagaaga
    28381 agatctaacg aaaactcagt cattaattct tgaacaattt ctgtctttct tctttctctt
    28441 tttcctcctt caatcggagt tctcttaact tttttaggat ggcattctcc gctctcaggt
    28501 actcattttc tgcttgaaga cgttctaatt ctgtcctctc ttcaggtctc gtttttggat
    28561 tacgtcccat tttaggtact ctccctcttg ttttctcaac aatagtatac ccgtttttcc
    28621 tgtattgtgc tagccagtta agaagtatcg tacgacttgg gaggccgtat tcaagagaaa
    28681 ctctatcttt agtccagcct tcatgtcaga ctttatgaat catttcttgt tttaaatcag
    28741 gagaatagta acgatttttt ccttttttga cgaactctat tccgtaacga tcaatcaatt
    28801 taatcatgta cctaagatta gaattgttta tcccaaattt atttgaaagc ttctctaagc
    28861 tatatccttg ttttctaagt tcatagatct gaactttatc atcataagtt aatttcataa
    28921 taaaaacacc ccaaaagtta gattttttct gtctaacttt tggggtgtag ttcatgtaca
    28981 cctgatatga tgcgttttat aatttttaag cctttttgcc cagcctcgtc aaaagtaatg
    29041 ttttgacaca aaatctgtga caaaacttta gttttaaagg tttttaactt tgtatatact
    29101 agttttaaga aaaggaggat gatctaatgg aagaaaaagt atcattgaag gtcagggttc
    29161 aaaaactagg gacatcgctt tcaaatatgg ttatgcccaa tattggagca tttattgctt
    29221 ggggagtatt gactgccctc tttatcgctg atggctatct gccaaatgaa cagttagcta
    29281 ctgttgttgg tcctatgtta acgtatttat tgccaatcct gattggttac acaggtggat
    29341 atatgatcca tggccaacgt ggtgccgttg taggagctat tgctactgtt ggtgcaatca
    29401 caggttctag tgttcctatg tttatcggag ctatggtaat gggcccactg ggaggatgga
    29461 ctatcaagaa atttgatgag aagttccagg aaaaaattcg tcccggattt gaaatgttag
    29521 ttaataactt ctcagctggt ctcgttggtt ttgcattatt gcttttggct ttctacgcaa
    29581 tcggtccagt cgtatcgact cttactgtag ctgttgggaa tggtgttgag gctattgtca
    29641 atgctcgcct ccttcctatg gctaatatta tcatcgaacc ggctaaagtc ctttttctca
    29701 ataatgccct caatcatggc atttttactc ctctgggagt agaacaggta gctcaagctg
    29761 gtaagtcaat tctcttccta ttggaagcta atcctggacc aggcctggga attctattag
    29821 cttatgctgt attcggtaaa ggttctgcta aatcttcttc ttggggggca atggttattc
    29881 atttcttcgg agggattcat gaaatttact ttccttatgt tatgatgaag cctactctat
    29941 ttttagctgc tatggcagga ggtatctctg gaacttttac ttttcaactc ttagacgctg
    30001 gtcttaaatc tccagcttca ccaggttcta ttattgcgat tatggctacg gcgccaaaag
    30061 gtgtttggcc tcatctaaat gttcttttag gtgttttagt ggcagcagtt gtttctttcc
    30121 ttgtagcagc ccttattctt catgcagaca agtcaactga ggattcgctc gaagctgctc
    30181 aggcggctac ccaagcagct aaggctcagt ctaaaggtca gttagtatca acttctgttg
    30241 atgcagttgt ttcgacagac tcagtggaaa aaatcatttt cgcctgcgat gctggtatgg
    30301 gaagctctgc tatgggagct agtattcttc gagataaggt taaaaaagca ggtctagaga
    30361 ttccagtatc taatcaggca atctcaaatt tgcttgatac accaaaaaca ttaattgtta
    30421 ctcaggaaga actgacacca agagctaaag acaagagtcc aagtgctatt catgtttctg
    30481 ttgataattt cttagcgtcc cctcgttatg atgaaattgt agcttcatta acaggagctt
    30541 ttccaatagc agaaattgaa ggagatatac caacttcagc accagtagat agtcaggaaa
    30601 ttgaccttaa ccatattgat gctgtagtag ttgcttatgg taaagcacag ggaactgcaa
    30661 ctatgggctg tgaaacgatt cgggctatct ttagaaacaa gaatattcgt attccagttt
    30721 ctactgccaa aatttcagaa ttaggtgaat ttaattctaa aaacataatg attgtaacaa
    30781 ctatttcttt acaggcagaa gtgcagcaag cagcaccgaa ttctcaattt cttattgtgg
    30841 atagtttagt aacaacacca gaatatgaca aaatggctgc tagaatgtac aaatagaact
    30901 agaggtttct aaattacgaa tgctattaac caaacgagaa gaacaattat tgaaggcttt
    30961 cctacatgta gggaagcttt caatgcaaga tatgactgaa atcttacagg tttcatctag
    31021 aacaatttat cgaactttat cagatttgac agatagcatg gagcaatatg gaatcgaaat
    31081 aacgaagcat gggaaatact atattttgac tggagagttg gatgatttgc cgacagaact
    31141 tgaagtgtta gttgagtata gtccccaaga aagacaagag ttgattacct atcgccttct
    31201 gactgagagc ggttttgtca ccaatgaagc attgcaagag tgcacgaaag tcagtaatgt
    31261 aactattatt caggatattt cagatattga taagcgtctt ttagactttg atctgaaaat
    31321 tgaacgacaa aaaggttatc ggatttctgg tgattcagtt ggtaagagaa gatttttggc
    31381 tattttactg acaaactgta tctcagtagc agatttttca accggtaatt ttgggagctt
    31441 tgatatttta gaagcagata gaactaggct ggccagtcag attgttaata agcaactgtc
    31501 aggttttcca gatatggatg ctaggatgaa gatgtttttt gcgatcttgt tatctcttat
    31561 aggtcaggag caaaacattg aaaattcacc taatactagt aagcaggctt tggaaatttc
    31621 tcaaaaaatt tttcaagctt actctaagca gactgcacaa ttttatagta ttcaggaaat
    31681 tatctatttt gcgagcatct tggatgaatt aatcattaaa cgtcaggaca atccgctctt
    31741 tacggagaaa tttgatggtg aatttttcta caatatttca aatctgattg atacggtttc
    31801 catgtatacc aagattgact tttttaagga caaggtttta ttcaattttc ttttccatca
    31861 tattcggctc agtttaggcg tccctatcct ttttcagggt gaaaatttgc cagaatctat
    31921 ccagatttta gttgaaagga ataaatttct ttatacagtc atcagtcttt tagtgaatga
    31981 tatttttccg aaatatcttc atacagagta tgagtatggc atgattgccc tacattttat
    32041 ctctagctta ggccgtagtc cagagattta tccagtccgt gttttgcttt taacggatga
    32101 acgtcgggtc actagagatt tattagtcag taaaattaag agtgttgctc cttttgtaga
    32161 gttgatagat attcagtctc tagtagatta ccacagtatt gatctcagtc agtatgatta
    32221 tattttatct accaagccgc tgactaatca ggaaatcgat gtaatttcta gttttccaac
    32281 cgtcaaagaa ttgcttgaat tacaggaacg acttcagtat gtacaggcac atcgtacaat
    32341 tgtcgcgcgt gatgctatcg ctccagagaa aagttatgac ttgcaagatt atttaatatc
    32401 tagtagtcag cttttgagtc aatttgagtt ggttcaattg gagaataatc aatcatttga
    32461 gcacacggta gaacaaatca tccaatatca gaagaatgtg agtgacagag attacctaac
    32521 aagaaaattg ttatctcact tccagaatag tcctatggct attcctaata ctggtctggt
    32581 gcttttacat agtcagtcta gcaaagtaac aacaaatagt tttactatgt ttgaactcaa
    32641 actacctatc tccgcattgt caatgaaacg agaggaagaa gaggtcaaaa ggtgtctgct
    32701 aatgctaatg tctaaagaag ctagcgagga agcgagagat ttaatgacag ctattagtca
    32761 gtcgattatt gaaaatcatc tttatacaga gatttacaag acgggaaatc aatccattat
    32821 ttatcagatg ctaaatacta tttttaacga aaaaattaag aaattggaga actaatatga
    32881 aacttgaaaa acatttgatt aagcttaata aacaattttc taacaaggag gaagctattt
    32941 gttattgtgg gcaagttctt tatgagggtg gatatgttaa tgaagactat attgaagcca
    33001 tgattgagcg agataaagag ctatctgttt acatgggtaa ctttatcgcc ataccgcatg
    33061 gaacagatgc agcaaaaaag gatgtactca agtctggtat tacagtcgtt caagtcccta
    33121 gaggggttga ttttgggaat gtatctaacc ctcaagtggc aacggttctt tttggtattg
    33181 ctggtattgg taatgaacac ttggaaatta ttcagaaaat ttctatcttc tgtgcagatg
    33241 tagataatgt tcttaaacta gcagatgctc agtcaaaaga ggaagtattg cgcttatttg
    33301 atgctgttga ataattgaat ttcgtcattt gtcatctagt atatatgtcc ctcaaatagg
    33361 aaaaggagaa attgaatgaa acattctgtt cattttggtg ccggtaatat cggtcgtggt
    33421 tttataggtg aaattctatt taaaaatggt ttccatattg attttgtgga tgtcaataat
    33481 cagataattc atgctctaaa tgaaaagggc aagtatgaaa ttgaaattgc acagaaagga
    33541 cagtctcgta tagaagtaac taatgtggct ggcattaata gcaaagaaca tcctgagcaa
    33601 gtcattgaag cgattcaaaa gacggatatt attactactg caatcggacc taatatactc
    33661 ccttttatcg ccgaacttct agccaaagga atcgaagctc gccgagttgc aggaaataca
    33721 caggcattgg atgttatggc ctgtgaaaat atgattggcg ggtctcaatt tctttatcaa
    33781 gaagtcaaga aatatttaag tccggaaggt ttgacatttg ctgataacta cataggtttt
    33841 ccaaatgctg cagtagacag gattgttcca gcacaaagtc acgaagattc cctttttgtt
    33901 gtggtcgagc cctttaatga atgggtcgtg gaaaccaagc gtcttaaaaa tccagattta
    33961 cgtctaaaag atgtgcatta tgaagaagat ttagaaccct ttattgagcg aaaacttttt
    34021 tcagtcaatt ctggacatgc aacttcagct tacattggtg cgcattatgg tgccaagaca
    34081 attttggaag ctcttcaaaa tcctaatatt aaatctcgga ttgaatctgt attagctgaa
    34141 attcggagtc tcttgattgc caaatggaac tttgataaaa aagaattgga gaattatcac
    34201 aaagtcatta tagaacggtt tgaaaaccct ttcatagtgg acgaggttag tcgcgtagct
    34261 cgtactccaa tccgaaaatt aggctataat gaacgattca tccggccgat acgtgaattg
    34321 aaagaactca gtttgtcata taaaaaccta cttaaaacag ttggctatgc ctttgactat
    34381 cgcgatgtaa atgatgaaga aagtattcga ttaggtgaat tgttggctaa acaatcagtc
    34441 aaagatgttg ttatacaagt tacaggttta gacgaccaag aattgattga gcaaattgta
    34501 gagtatattt aatctttttc gaaaatctct tcaaatcagg ttagcatcgc tttgtcttag
    34561 gcatatgttg ttctatctac aacctcaaag cagtgctttg agctgactcc gtcagtcttg
    34621 tctgcaacct caaaacactg tttgagttat ctgcggtaat ctttctagct tgtctttgat
    34681 ttttgttgtt atttataagg taaaagaagc tggacaaaaa gtcttcaaaa tcggaaaaag
    34741 gcagcctatc gggtgttcaa aaatcttgat aggatgtcct ttattatgga aagccttatt
    34801 ggattttctc ctcagattga gtttttgatc agctttatga gataggtttt gctagagatg
    34861 tagcccatca tgttattttt atggacggtg ggaaaattgt tgaaaaaaat aatgcccatc
    34921 aattctttag tcgtccaaga gaagaacgaa ccaagcaatt ttggaacgaa ttctttcgaa
    34981 tgcgatct
//
LOCUS       DAVHLA010000018        34518 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVHLA010000018 DAVHLA010000000
VERSION     DAVHLA010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34518)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34518)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34518
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.018"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(97..499)
                     /locus_tag="VVO77_001021"
                     /pseudo
     CDS             complement(97..499)
                     /locus_tag="VVO77_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(575..1015)
                     /locus_tag="VVO77_001022"
     CDS             complement(575..1015)
                     /locus_tag="VVO77_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU5693046.1"
                     /translation="MKAPIPKAPLAHSLGSASIIAHTIHQKFNLKVPNYRQEEDWARM
                     GLPITRKEISNWHIKTSQYYLEPLYNLLREKLLEQALLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHDQRRSGSVVQEFLGNYSGYMHCDMLRQ"
     gene            1006..1313
                     /locus_tag="VVO77_001023"
                     /pseudo
     CDS             1006..1313
                     /locus_tag="VVO77_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1336..1686)
                     /gene="tnpB"
                     /locus_tag="VVO77_001024"
     CDS             complement(1336..1686)
                     /gene="tnpB"
                     /locus_tag="VVO77_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEU5693047.1"
                     /translation="MTIHLSSLGQVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGRLTWPSTEKDVKALTPEQVDWLMKGFS
                     ITPKINLSESRDFY"
     gene            complement(1667..1852)
                     /locus_tag="VVO77_001025"
     CDS             complement(1667..1852)
                     /locus_tag="VVO77_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693048.1"
                     /translation="MPQPIVPVEIPQSRPFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MVEQLLDKVLLYDNSSI"
     gene            complement(2156..3718)
                     /gene="guaA"
                     /locus_tag="VVO77_001026"
     CDS             complement(2156..3718)
                     /gene="guaA"
                     /locus_tag="VVO77_001026"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEU5693049.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            3860..4558
                     /locus_tag="VVO77_001027"
     CDS             3860..4558
                     /locus_tag="VVO77_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU5693050.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYSDQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQISYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(4601..5497)
                     /locus_tag="VVO77_001028"
     CDS             complement(4601..5497)
                     /locus_tag="VVO77_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEU5693051.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILHIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(5506..6441)
                     /locus_tag="VVO77_001029"
     CDS             complement(5506..6441)
                     /locus_tag="VVO77_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEU5693052.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSAPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARFLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(6438..7163)
                     /locus_tag="VVO77_001030"
     CDS             complement(6438..7163)
                     /locus_tag="VVO77_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEU5693053.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(7247..7882)
                     /locus_tag="VVO77_001031"
     CDS             complement(7247..7882)
                     /locus_tag="VVO77_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEU5693054.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEKYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(7884..8711)
                     /locus_tag="VVO77_001032"
     CDS             complement(7884..8711)
                     /locus_tag="VVO77_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU5693055.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(8733..9659)
                     /locus_tag="VVO77_001033"
                     /pseudo
     CDS             complement(8733..9659)
                     /locus_tag="VVO77_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809127.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
     gene            10310..10921
                     /locus_tag="VVO77_001034"
     CDS             10310..10921
                     /locus_tag="VVO77_001034"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEU5693056.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            10966..11694
                     /gene="rlmB"
                     /locus_tag="VVO77_001035"
     CDS             10966..11694
                     /gene="rlmB"
                     /locus_tag="VVO77_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEU5693057.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFLNRL"
     gene            complement(11733..12644)
                     /gene="trxB"
                     /locus_tag="VVO77_001036"
     CDS             complement(11733..12644)
                     /gene="trxB"
                     /locus_tag="VVO77_001036"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEU5693058.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVKEIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(12710..12934)
                     /locus_tag="VVO77_001037"
     CDS             complement(12710..12934)
                     /locus_tag="VVO77_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEU5693059.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTAGARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(13012..13755)
                     /locus_tag="VVO77_001038"
     CDS             complement(13012..13755)
                     /locus_tag="VVO77_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU5693060.1"
                     /translation="MIKISNLSKSFSGQTVLDHLNLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(13755..14555)
                     /locus_tag="VVO77_001039"
     CDS             complement(13755..14555)
                     /locus_tag="VVO77_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU5693061.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(14713..15069)
                     /locus_tag="VVO77_001040"
     CDS             complement(14713..15069)
                     /locus_tag="VVO77_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEU5693062.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLSVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(15082..15594)
                     /locus_tag="VVO77_001041"
     CDS             complement(15082..15594)
                     /locus_tag="VVO77_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEU5693063.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDINK"
     gene            complement(15594..16088)
                     /locus_tag="VVO77_001042"
     CDS             complement(15594..16088)
                     /locus_tag="VVO77_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU5693064.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            16223..16669
                     /locus_tag="VVO77_001043"
     CDS             16223..16669
                     /locus_tag="VVO77_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEU5693065.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMINNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            16666..17313
                     /locus_tag="VVO77_001044"
     CDS             16666..17313
                     /locus_tag="VVO77_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEU5693066.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKNVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASVLQYIAIVYYM"
     gene            complement(17334..17915)
                     /gene="pdxT"
                     /locus_tag="VVO77_001045"
     CDS             complement(17334..17915)
                     /gene="pdxT"
                     /locus_tag="VVO77_001045"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEU5693067.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLLIREAILSGLPVFGTCAGLILLAKEITSQKESYLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(17916..18791)
                     /gene="pdxS"
                     /locus_tag="VVO77_001046"
     CDS             complement(17916..18791)
                     /gene="pdxS"
                     /locus_tag="VVO77_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEU5693068.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(18943..20322)
                     /locus_tag="VVO77_001047"
     CDS             complement(18943..20322)
                     /locus_tag="VVO77_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEU5693069.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            20616..21539
                     /locus_tag="VVO77_001048"
     CDS             20616..21539
                     /locus_tag="VVO77_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEU5693070.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGISPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     IFWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            21599..22204
                     /locus_tag="VVO77_001049"
     CDS             21599..22204
                     /locus_tag="VVO77_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU5693071.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            22223..23467
                     /locus_tag="VVO77_001050"
     CDS             22223..23467
                     /locus_tag="VVO77_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU5693072.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(23583..23840)
                     /locus_tag="VVO77_001051"
     CDS             complement(23583..23840)
                     /locus_tag="VVO77_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEU5693073.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(23882..25918)
                     /locus_tag="VVO77_001052"
     CDS             complement(23882..25918)
                     /locus_tag="VVO77_001052"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEU5693074.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKEIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGGRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKKIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(26130..27047)
                     /gene="glyQ"
                     /locus_tag="VVO77_001053"
     CDS             complement(26130..27047)
                     /gene="glyQ"
                     /locus_tag="VVO77_001053"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEU5693075.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRAKLLAEDAE"
     gene            complement(27415..28176)
                     /locus_tag="VVO77_001054"
     CDS             complement(27415..28176)
                     /locus_tag="VVO77_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEU5693076.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSEQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFFTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKIFPLLDWFVQQKLIEKEI"
     gene            complement(28449..29291)
                     /locus_tag="VVO77_001055"
     CDS             complement(28449..29291)
                     /locus_tag="VVO77_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEU5693077.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYHAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(29405..30796)
                     /locus_tag="VVO77_001056"
     CDS             complement(29405..30796)
                     /locus_tag="VVO77_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEU5693078.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKVEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKSFSDQDLSAWNFDYKDS
                     QIILYSSPVLENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(31031..31408)
                     /locus_tag="VVO77_001057"
     CDS             complement(31031..31408)
                     /locus_tag="VVO77_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEU5693079.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMSYSAQDFYTSIDV
                     LAELDNGIQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIAPV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            31641..32618
                     /locus_tag="VVO77_001058"
     CDS             31641..32618
                     /locus_tag="VVO77_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEU5693080.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYSKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFGKANDATYHAQQLDNSIDLNGDGTLFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQDPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            32615..33697
                     /locus_tag="VVO77_001059"
     CDS             32615..33697
                     /locus_tag="VVO77_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU5693081.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTLIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGSEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(33761..34518)
                     /locus_tag="VVO77_001060"
                     /pseudo
     CDS             complement(33761..34518)
                     /locus_tag="VVO77_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT        10228 a         7736 c         6231 g        10323 t
ORIGIN      
        1 agctcttgct ttagctcctt caaaactttg agaaaaaacc accctcgctt ttttaaactg
       61 agcttaggct aaaagagtcc agtggactct tttactccgt cccataacca atgatttaat
      121 ggcgcgttca gctagattat tggaaaggac cagatgtccg tcttttaaaa tggtcttaaa
      181 ggtttcttca tacttgaggc tgtattcaat tgcccttcct ggttttgaac ctgctaaaac
      241 tgactgacgg cggcaccaag caaagaagtc ttccattaag ggctggacgt ttctgtagtc
      301 gttcatcagc tggcaaagcc tcccagtctc tttccaaggc aaataactgg tcacgatagg
      361 ctaaaccttt agctcctaag gatgatttat ctgcttgctt gggggtcgct tcaaaaaatt
      421 tccttctcac atgcgcccaa catccaacaa gttcagcttc ttccagttga cgataagctt
      481 ctagcggttc gcagtttacc aagcttagcg tcgccttgct cctaaacctt agactgctat
      541 cgcataggca gaactagagg actaaagttc taagttactg ccgcaacata tcacaatgca
      601 tatagccaga ataatttcct aggaattctt gcactaccga accactccga cgctgatcat
      661 ggtggtacag cgtaatccct tgtttctcag ctttcccaga caaaaaagtc caatagtaag
      721 tcagctgact atcactttct aagacccgat aagaggtttc atctgcatga agaagagctt
      781 gttctaacaa cttttctcgt aaaaggttat aaaggggctc caaatagtat tgactcgtct
      841 tgatatgcca attagagatt tccttacgtg tgattggtaa acccatccta gcccaatctt
      901 cttcttggcg ataattgggt accttcagat taaacttctg atggatggtg tgagcgataa
      961 tagaagctga gccaaggcta tgcgccaaag gggctttagg aataggagct ttcacaagct
     1021 tatccagatg attatctttt actcgttatg gacaatgcta tatggcataa atcaagtacc
     1081 ttaaagattc cgactaatat tggctttgca tttattcctc catacacacc agagatgaac
     1141 ccattgaaca agtgtggaaa gagattcgta aacgtggatt taagaataaa gcctttcaaa
     1201 ctttggaaga tgtcatgaat caacttcaag atgttataca aggactggag aaggaggtga
     1261 taaagtccat cgttaatcgg agatggacta gaatgctttt tgaaagcaga tgagtataaa
     1321 aagaaagtcc tcatttcaat agaaatcacg actttctgat aaatttattt tgggagtgat
     1381 agaaaagccc ttcataagcc aatctacttg ttcaggtgtg agagctttga catccttttc
     1441 tgtactgggc caagtcagtc tgccgttctc aaagcgttta tatagtagcc aaaatccttg
     1501 accatcccag taaagggctt taaagcggtc tttacgtcca ccacaaaaga gaaaaacttg
     1561 accggagaaa ggatccaatt caaagtgggt tttaaccaga taagccagtg aatcgattcc
     1621 ttgtctcata tcagtcttcc cacacacgag atagacctgc cctaggctag atagatgaat
     1681 tgtcatagag caacacctta tccaaaagct gttctaccat ttcgagattg agagattgaa
     1741 aaaaacttac ttcaagcttg ccaatacgaa ttttaagcag aatatcattt ctctttttag
     1801 aatcaaaagg acgagattgt ggaatctcta caggaacaat aggttgtggc attaaaatat
     1861 cctccaatag ttttacttta ctaatagtat acaggaggaa ctccatgaat gatagatacc
     1921 ttgttatgac gcgcttacta tattagaaag ttggctctct aattaaatta attctcatta
     1981 tatatatcaa aagaccgcag tttgaaaact acggtctaat tttttgtcca aatgtaaatc
     2041 acttggaact attattcaat ttattctttt tagtaaatgt tcccgtttta atcccagtta
     2101 cagtttttaa tcctctgtaa ccgttgattt tacaaagctt ttaatttttt tgcgattact
     2161 cccactcaac tgttgcaggt ggtttacttg taatatcgta gacgatacgg ttaacatgat
     2221 ccacttcatt tacgatacgt actgagattt tttgaagtac ttcccatgga attttggcaa
     2281 aatcagcagt cataccatcg atagaagtga tagcacggat tgcaatcgtg tagtcatacg
     2341 tacgaccgtc acccataaca ccgactgaac gaacgcctgt gttaacagtg aagtattgcc
     2401 aaatatcgcg gtcaagtcca gctttagcga tttcttcacg aagaatagcg tctgattcac
     2461 gaacggtttc aagtttctct tcagtgattt cacccatgac acggatagca agtcctggtc
     2521 ctgggaatgg ttggcgccat acgatatggt ctggcatacc aagctctgta ccaagagcac
     2581 gaacttcatc cttgtaaaga gtattgagtg gttcaatcaa ttcaaactgc atatcttctg
     2641 gaagaccacc cacgttgtgg tgtgacttga tagtttgagc tgtatccgta ccagactcga
     2701 taacatctgt atataaagta ccttgagcaa ggaatttcac atctttgagc ttgcttgctt
     2761 cgtcatcgaa tacatagaca aactcgttac caatgatttt acgtttttgt tcaggatcag
     2821 aaacgccagc aagtttgtca aggaaacgtt tagcagcgtc tgctttgacg atattcaaac
     2881 caaacttacc accgagcatg tccataactt gatcagcttc gcctttacga agaagaccgt
     2941 ggtctacgaa gatacagatc aattgatcgc caatcgcttt ttggagaaga accccaacga
     3001 cagatgagtc aacaccacct gatagaccaa gaaggacacg tttatcaccg acggtttcac
     3061 gaattttttt gatctgcatg tcaatgaaat tatccattga ccagtcacct ttagccttac
     3121 aaatgttaag ggcaaagtta cgaaggatat catttccgta tacagaatga cgaacttctg
     3181 ggtggaattg gataccgtaa atgtgtttat ctgggttttc gatggctgcg tatgggcagt
     3241 cagctgatgt acctgtacga acaaagtcag caggaatctc agtaaccgca tcaccatggc
     3301 tcatcaaaac agtctgttca tcaggtgttg attcaaaaag cgctgatggt gtgtgagtta
     3361 gggttgattg accgtattca cgatttccag catcacctgc aggaacaact tttcctccaa
     3421 gtttatgggt caataactgc ataccataac agattcccaa aattggaatt ccgagttcga
     3481 agatttctgg gtcaatatca aatgaaccat cttcatatac agaatttgga ccacctgata
     3541 gaataattcc tacaggattg acttcacgaa cttcagcagc tgaaatttta tggcttttta
     3601 gttctgaaaa aacaccaatc tcacggatac ggcgtgaaat cagctggttg tactggctac
     3661 catagtccaa tacgatgatt ttttctacat cttgcaaatc agttgaaatg ttgctcatct
     3721 ttttcctttc tcaaaagaaa tatcttttct caatattcta tcacaaataa gggcgaatta
     3781 ccaactaaac aaggcgaagt ttgacttttt ctagtttatt ggggtacaat agagaaaaga
     3841 tagaaatgaa gtgaaaaata tgctacctgc ttatatgaaa atccatgatc agataaaaaa
     3901 ggatattgac gagcaccgtt gggctattgg tgagaggctt cccagtgaaa gagatttagc
     3961 tgagcagttt gcggtcagtc gcatgaccct ccgccaagcc gtatctctat tagtcgaaga
     4021 aggcgtctta gagcgccgtg taggaagcgg cacctttgtt tccagtactc gagtacaaga
     4081 aaagatgcga gggacaacca gttttactga aattgtcaaa tcccaaggta aagttccctc
     4141 tagccagctc atttcctaca aaaaaaccat tcccaatgag caagaagttg ccaagctagg
     4201 aatttttcca acggacaata ttatccgaat ggagcgggtc cgctattccg accaagttcc
     4261 cctagtttat gaagttgctt ctattcctga aaaattcatt aaggacttta aaaaagaaga
     4321 aatcaccagt catttcttcc aaaccttgca aaaacatggc tatcgtatcg gtaaatccca
     4381 acagaccatc tatgctcgcc ttgctaaaga aaagattgcc cactatttgg aagttgaaaa
     4441 aggacatgct attcttggat tgacccagat ttcctaccta gaagatggta ctgcttttga
     4501 atacgtaaaa agtcaatatg taggcgaacg ctttgaattt tatcttgaaa ataattagat
     4561 taccacgcaa aaactctctg tcacggacaa agagtctttt ttatttttct aagaataaat
     4621 ctttcaaaga aatcaaagtt acagcaaaca atatcattgc cataccaaga aaatcaatgg
     4681 gataaaattg ttcattcatt attaagaagg caaagaaaat cgccgatatt ggctcaattg
     4741 aagccaacaa gcttgacttg accggtccta tcagactggc tcctttaagg aaagctgtat
     4801 aggcaaagac agtcccgata aggataatgc ctgcaaacgc aaggagaaaa tcaagactag
     4861 tcgggatatc ggcctgtaga acccctgtaa aaggaagggc gaccaaacct gctatgacca
     4921 ttcccacacc aatgaccaag ctgctccccc actttttaat caaggctatg tgtaaaatga
     4981 tatacaaagc ataagtcaag gcagaaaaga gaccccagaa cagaccagca ggtgtcatgg
     5041 ataactggtc caactgccca tgtgttgcga tcaggaaggt tcctccgatg gcgaatatga
     5101 tggaaactat ctctcccagt gtcggtgcca ccctatcctt gatacagcta taaattaaaa
     5161 ttccgacagg acaaacatac tgaagcaccg tcgctgttcc cgcattggtc tcctgaatag
     5221 cagacagata ggcgaattgg ttgagaaaaa gaccaatcag agcaaaaata agaagagaca
     5281 gcaaactctt tctatccttt aaaaagacca gtattttatc ctttgcagta gcataagcca
     5341 agagcatgag aattccacca gcgattaaaa gacgcaagtt agtcaagacc agagccgaaa
     5401 ttccgtgtgc cattaggtat tggccactcg ttcctgacaa cccccaagca ataccagcca
     5461 caactgttag taaagtccct tttaaactat ttgacatgtc tctccttact cttctttgcg
     5521 aatcaagttc atcacttgat tgcggtctaa tatccattga gctctctcgt ccttttcata
     5581 ggtacgattc gataggaaaa tagtggcttc ttgcttctga cgattccaca tgataaaggt
     5641 acctgtatag cccgtatggt ctagccaatc tccttccaaa ttccatgcta aagaacgttc
     5701 cttgtcatcc aaaggagaaa aattttgatt taagtctctt gcaaaatcat ctgctaaata
     5761 gtgttctaaa aagatttgta aatcctttat agtcgaaaat aaaccagcac tcccagcatg
     5821 tctacccagg aaacgagcct tgggatcatg cactatgcct gcctctacac ctctaactgt
     5881 tggaacagca agctcaactg gcccaaactt agtttccgtc attccccaag gtttccagac
     5941 ttgatccttt aaaatcacat ccaaatcttg attaaaaatt ctttccaaaa taaagcccaa
     6001 cagcaaaaaa tggacatccg aataaagaaa ggctggctga cttcgtctgt tgagatgaaa
     6061 catcgcttcc tttaattcag gggctgttaa aagatcacga ttaggaataa aaggatcaag
     6121 gtctgttgca tgagtcaaga gctggcgaat agtgatgtct ggataatcac tctcaggtaa
     6181 aaaatctatt accagtctat caatatctaa ttgacctatt tcccacaaga aggtacaaac
     6241 tgtgccaacc ccaacaacct tgctgacact agctaggtca taaactagtc ctgcctcagt
     6301 ctgcaagcca tgctctgggg cactctggcc taaatagaac tctgtccatt gattgtcctt
     6361 aaaatacgca aaagaggctc cgggataaat tcctgcctcg atttgttctt ctattttttt
     6421 aataatcttg gtccacttca tacttcttca aaccacaatt caacattatt tctatcttta
     6481 ccaaggaaga atttttcaga cttaggaata aaatattcag tagactcaaa cttctggcga
     6541 agacttgcta tgtctaattc attgaccaag aacttgagca tagataagtc ccaggtaacc
     6601 gtattgtcca cagtcaaatc ctgcccctga gctggaataa aatcaaggga tgccccaatt
     6661 tcagatgatt ccaagaaact ttcgatatca gttgggagat gtaattccat agaaatctca
     6721 aatttactta aagaaattga tgccaaatct gtttgaaatt caggcttttc tcctacttct
     6781 actagacttg ctctgtcatc ttccgcatga atcaaaatca aatcatcttc tggtgagaaa
     6841 atttcaaaag cgtagccatt ttgaccttta tataatcgat gaatcgaatc tgttttagat
     6901 aagattcctt caatttctaa gggattttcc accttgacaa tcaatctagc tagttttttt
     6961 cttccctcta ccttacgagt acgcatactg ggagcttctt ctaaaaccag cttttcaaga
     7021 cccgtttggt cacctagtga cagaaaggcc gattcttcta acagggcctt cattccaagg
     7081 gtttcaatat aaaatgtttc atttaatttt ctattattag cttttaaagt aggaataatc
     7141 cgtacaatct gatttacatt cataaattcc tccgtcactt tttattttaa aggattttag
     7201 aattttttac aagatattat gctcaaattt aacattattt agctatttag taaagatagt
     7261 ctttcaaggc ttttgacaaa gcctgataac cagcaatact gaggtgcagt ccatcagttg
     7321 tatattcttt tttgagttgg cctgcttggt ctgtcaaaca atcaaatact ggcacaaatt
     7381 ccacctgcat ataggcagat gcaagctctt gataggcttg attccaattc tgaatttttt
     7441 cattcgagcg gatatagact gcctgctggt acttctctcc ctcattgaca ggcaaaatgg
     7501 aaagcaattt aatctctgtc aatggataat cgcgagcaac ggattgaatg atagcttcga
     7561 gattattgag agcctcattc acaggaacat cctttccgat atcatttgtc ccaatcagaa
     7621 gaaaaatttt atctactgct ccaccatata gatgagcatc aaggttctct agtaacagtc
     7681 ctgtctgata gccacgaatt cctcgattga caatcgtctt tgaagtccca aatagctcct
     7741 gtagaggata atactcgaca atggaatccc caataaaaag aatgtttggt tctacaacag
     7801 aaatgtgatt taggtgacga tatttggttt gaattttttc ttgttccttt aggagccaat
     7861 tttctaataa ctgtactgcc acttcattct cctttttcta accagttttc caagacttga
     7921 taaactcctc cttggctgtt ggctggtgct agagcagtcg ccacagcttt ggctttctca
     7981 tcagcatttt ccatcgcata ggcaattcca gccatttcaa gcatttcaac atcattttca
     8041 ctatcaccaa aagccatgat ttcttgggat ttcaagtccc agcgcttgag taattcctcc
     8101 aagccccatg ctttatgaat cccagcttgg aggatatcaa tgcaaccata gccactggat
     8161 acagctcgga cacggccatc aaagagagca ttgatttctt ccaaaaccga actcaaacgt
     8221 tcctcaccaa caaccatgct catcttgagc acaccaccaa agaggtcaga tgttaattca
     8281 tccacaaatt gcatccgttg gtagaatttt tcaatcattt ctggagtcat aaaactttca
     8341 agatctgtaa aaatcgtacc ttccttgaca aaatcaccct tcatccccgt tacaacaaac
     8401 tggtcctgac acgctcgacc cttgaaatga gccaaagcct tgttgacaat ggcgtcatcc
     8461 catgtctgag cctgaatcaa ttcattgttt tcaaaaatac gagcgccatt agcaacaacc
     8521 agaaccactc gatccaccaa gggactcagt agttgtctca tgcggtgaat ttcattgccc
     8581 gtcgcaatga caaaacgaat gcccctttga tccaactgat ctaaaatctt ttccaatcgt
     8641 gggagatcaa gctgacctct agcatccagc aaggtcccat ccatatctgt cgcaattacc
     8701 ttaatcatca tttactttcc tctggattca agctaatacc acttcaatcc cacatgttca
     8761 ttcatttctt tataggctgt atcaattcgt tccttagtcg cttcatctaa ctggtcacga
     8821 tgactgccat cctctataaa atcttccaaa atataagttt ggtaatgata caagggatat
     8881 ccttctggtg aaaaggttcc ctttggtgtt cgattgaccc aagtaggatg agctttagct
     8941 gttccgatag ttgtttttcc atccttcttc ttgatggtga catccatgag aacaccacgt
     9001 tcagtccact tagcattctc ttcatctccc atagattcaa tccgttgatt ggaaatgaag
     9061 ttccccattt aatagataat gagtttctta tctccatctt tttcaaccgt ttcagatggt
     9121 tcaacaacgt gaggatgccc tccaaagata atatccgctc cccaatcgat catcttgtga
     9181 taaagagctt tttgttcttc agttagttcc aatcgatact caacacccat ctgaagcatg
     9241 ataatggtga tatctgcttc cttctctgcc cgttcaattt caaccttcat cttatcttcg
     9301 tttaaatctg aaagataacg attatagtct tcctgagaaa tatactgctc aattccattg
     9361 aaaccatagg aataggctaa caatgcaacc ttgataccat tcacttcctt aatgaccagc
     9421 ggagcctgat cacgtggttc gtgcgtataa actccgattg gagtgattcc agctttctca
     9481 ataatatcgg ccgttgaaat aactccctca atttgcgaat ccaaaatatg attatgagct
     9541 aaatccagca catgataacc tgcctcctta atagcatcca taacttcagc aggagcatta
     9601 aagagaagat aacccgctaa ataatgatcc ttattaatgg ttccttcaaa atcaccaata
     9661 gctaaatctg ctgcttagtc cccttgcttg agccaaggag tcacatactc aaaattttca
     9721 tgaaagtcat aggtaccgtc ttctttttta gctgaaaaga aaagtccatc gtggtagagc
     9781 aaatccccgt gggccataat tctggcagtt ttttcctctt cctactcctg agacttttgc
     9841 ttagtcccct cttgagaaat agtatctcgt ttttgactag tcaagggatt ccttggaagc
     9901 tttcaaacaa caagaccaag cccattgata aatcaactgc tagcaagagt atcgccacaa
     9961 atcccttatt gctccacttg cgataactcc taaaaagttt accaagccct tcataaaacg
    10021 aaaagctaaa ccaccctgat ttcgattttg tcttctttgt atcttcattc tccctacttt
    10081 cttatgcaag ccttttcttt ttattatatc acagataagt atttctttca caattgaatt
    10141 gaacttccca tctattttct ataaatccta aatgccataa tgctttcaat tcttgtcatt
    10201 ttgtgatatc atgtagagga aatgaactaa tccacagtgg cttattccaa gtataccact
    10261 tgggctttgg cagtagctaa ctgcactaaa cataatataa ggagagaaaa tgtctgcaat
    10321 agaacgtatt acaaaagctg ctcacttaat tgatatgaac gatattatcc gtgaagggaa
    10381 tcctactcta cgcgcgattg ctgaggaagt cactttcccc ctatctgacc aggaaatcat
    10441 cctaggcgaa aagatgatgc aattccttaa acattcccaa gatcctgtca tggctgaaaa
    10501 aatgggactc cgcggtggtg ttggactggc tgctccccag ttagatatct caaaacgcat
    10561 tatcgctgtt ttggtaccta atattgttga agaaggcgaa actccacagg aagcctacga
    10621 tttggaagcc attatgtaca atccaaaaat cgtctctcac tctgttcaag atgctgctct
    10681 tggcgaagga gaaggttgcc tgtctgttga ccgtaacgtg cctggctatg ttgttcgcca
    10741 tgcccgcgtt actgttgact actttgacaa agatggagaa aaacaccgta tcaaactcaa
    10801 aggctacaac tccattgttg ttcagcatga aattgaccac attaacggta tcatgtttta
    10861 cgatcgcatc aatgaaaaag acccatttgc agttaaagat ggtttactga ttcttgaata
    10921 aagaaaatcc cgttgcaaga cggggttttg tgttataata gaggcatgaa aacaaatgat
    10981 attgtctatg gcgtccacgc cgttaccgaa gccctccttg caaatacagg aaacaaactc
    11041 tacctccaag aagatctccg aggtaagaat gttgagaaag tcaaggaact agctacagaa
    11101 aagaaggtgt ccatttcttg gacatcaaaa aaatctctct ctgagatgac tgaaggtgct
    11161 gttcatcaag gttttgttct acgagtgtct gaatttgcct atagcgagct agattacatc
    11221 cttgcaaaaa cacgccaaga agaaaatcca cttctattga ttctagatgg tctaaccgat
    11281 ccccataatc tgggttctat cttgcgaaca gccgatgcga ccaatgtttc aggtgtcatc
    11341 attcccaagc accgtgctgt cggagtaact cctgtcgttg ccaaaacagc cacaggtgct
    11401 attgaacacg ttccaattgc ccgagtgacc aacctcagtc aaaccttaga taaactcaag
    11461 gatgaaggct tctggacctt tggaacggat atgaacggta ctccttgcca caagtggaat
    11521 acaaaaggga aaatcgccct catcatcgga aatgaaggaa aaggcatctc tagcaacatc
    11581 aaaaaacagg tcgatgaaat gattaccatt ccgatgaatg gacatgttca aagcctcaat
    11641 gccagtgttg ctgcagccat tctcatgtac gaagtttttc taaatagact ataaaaaagt
    11701 ttccagtcat ctgattggaa acttttttat gattaactat gttctgtgat aaacttgtag
    11761 gcttcttgac cagcgatagc tccatctcca actgctgttg ttacttggcg aaggtctttc
    11821 aagcgaacat ctccaactgc aaagataccg tcgactgcag tcttcatgtg gctatctgtc
    11881 acaatccagc ctgcctgatc ttggatattc aattctttaa caaaatcgct aagagggtcc
    11941 aaaccaacat agataaagac accaccgaag gcttgctctg tcacttgacc tgttttcaca
    12001 ttttcaaaaa cgacagattc tactctgttt tcacccttga tttccttcac tacagaatcc
    12061 cagataaagc tgattttttc attcgcaaag gcgcgatctt gtaaaacctt ttgggcacga
    12121 agttggtcac gacggtgaac aatggtaaca gtcttagcaa aacgagtcaa gaagagggct
    12181 tcttcaacag ctgaatctcc accaccaact accaataaat cttggtcacg gaagaaagca
    12241 ccatcacaca cagcacagta agaaacacca cgactgttca gttcttcttc tccaggcact
    12301 cccaaaggac ggtgtttaga accagttgct acgataactg tacgtgtttc atatgtttgg
    12361 tcatcagtca tcactttctt aaaatcacca tggtcttcga cattttcaac ataaccataa
    12421 atgtgctcaa caccaagatt ttcaagtggt tcaaacatct tttcagccaa ttcaggtcca
    12481 ctaatattag catatcctgg gtaattttcg atatcagatg tattattcat ctgaccacct
    12541 ggcagaccac cttcaatcaa agctactttt agattgcttc gagcagcata caaggccgca
    12601 gtcatccctg caggtccagc accgataata atagtatcgt acatatagat tccttctttc
    12661 ttgttgtaac tatctttatt ctaactcttt cttgtcaatc acgcaaggat tatgccttga
    12721 aaacaagaat taaactcata accgcaaagg ataatactgg gacaaccaag actccaatca
    12781 taatcatatc atagagatgg gcttggcgag ccccggctgt cttatcaact cccgacatgg
    12841 ctctcagacc aatccaaatc cctaaaaaaa tcagaacaag gatggtggtc aagatcaaac
    12901 tctcgaaata taaagaaaat agttgcagta gcatgatttc tctcatttct atctttttta
    12961 aagagtaaac tcagctagtc caactaactg agttttcctt tatctattat atcaaatata
    13021 agtccgtttg taactagcaa agaattcttt tgtccgctct tctttagggg tgtggataat
    13081 ctcatccgga gttccagact cgatgatttt ccccttatct aagaagagaa ttttatccgc
    13141 aacttgggct acaaaggaca tgtcatgact gaccaaaatc atggtctgac ctgacttagc
    13201 agcatctgca atagactttt ctacttcacc gaccaattct gggtcaaggg ctgaagttgg
    13261 ttcgtctaag agcaaaacat ctggtttcat agcaagcgca cgcgctaggg caacccgttg
    13321 cttctgtcca cctgataaat ggcgaggata atggttttca cggtccgaaa gcccaacctt
    13381 agccaactct tccttggcaa tcttagtcgc ttcttggtca gataatttct tgacaacaac
    13441 caagccttct ttcacattat caagtgctgt tcggcgttca aataaattaa actgttggaa
    13501 aaccatagac aacttacggc gtagggcaag gatttcttct tgagtgattt tagaaaaatc
    13561 aactgaaaaa ccatcaatct gaatagagcc actgtcaggt gtttcaagat aattgagact
    13621 gcgaagaaag gttgattttc cagctcctga agaaccaatc aaggctacaa cttccccttt
    13681 ttgaatatcc aagttcagat gatccaagac agtctgtcct gaaaaggatt tgcttaaatt
    13741 cgaaatctta atcattaacg aaggtctcct ttcacatctg tttgcactgt atcaggtgca
    13801 gaaatagcca tttttctctc gatgaaacga ccgaggcttt caattccgat attgactacc
    13861 caataaacaa gggcaacgga gatgaagcgt tcaaaatagc gataatcagc tccacctaga
    13921 atctgagctt gggcaaagac ttccacaaca cccgcactaa aagctagaga tgttcccttg
    13981 gtcaaaccga tgagggaatt aatcaaggtt ggagtagcta ccaccgctgc attaggaata
    14041 atcactcgtc gataaacttg cgctcgggtc atacccagac tgcgcgccgc ctcaatctca
    14101 ccaggattaa ctgagagaat ggctgcacga atggtttcac tagcataagc tgcctcatta
    14161 aaggcaaaag cgacaatcgc aaaagctgca gctggaatcg cattgatatt gagaccagtt
    14221 ccccattgct gattgagggc tttcaaagcc aaagggattc cgtagtaggt caacatgagt
    14281 tgcaccaaaa tcggtgtccc ttttaagaaa ctaacaaaga aggcctgcaa gggatataaa
    14341 atcttgacac gattgatctt cacaatggca aaaagaagcg ccaaaaccaa gccaaaaagg
    14401 gcaccaccaa ttgtcaacat aattgttgtt ggaagttgtt ggacaattct agggattcca
    14461 tcaaagaccg aacgtaggct aaacagcttg ccatccggaa tcaattgcat caagttttgg
    14521 taccaatctg atgctaaaat cgttgtaaca ttcataaaaa catcctcttc tgataatgat
    14581 tcattctacc atgcttctgc cgtcaatgaa attatttgct acggtcagat acagactttg
    14641 tctacctact agtttatcat actttgaaac agggaagtta tatattttat ctatcaaaga
    14701 gatagataaa aactatttca gtcccagttc ttcataagat tttcgataac cgatttgctt
    14761 aacagttcca ttttctacta aaatgggccg ttttaacaac ataccgtcac ttgctagcaa
    14821 ctcagccgct tcttggtttg acaaacttcc taccttatct tttagcccta attcacggta
    14881 tttgatacca ctggtgttga aaaattgctt caattcaaat cctgaggttt ctagccaatt
    14941 caaaatgact tcttggctag gtgtttcttc cacgatatgg acggctttat aatccacact
    15001 taattgattt aattcttgtt ttgctttttt acaagttgaa catttggggt attcgataaa
    15061 ttctaacatg tgcttctcct tctatttgtt tatatcttta aaatctacgc cttcatgctc
    15121 caagagccaa gctttctttt ccactcctgc agcatagcct gtcagacgct tgcctgctcc
    15181 caacacacga tgacaaggta ctaggataga ccaaggattg cgtcccactg ctccaccaat
    15241 tgcttgagca gaagccactt gcaggtcttg agcaatttgt ccataggtca ctgtctgacc
    15301 ataaggaatg ccctgtaaat agtcccaaac tctcttttca aaattcgttc cgattggcgc
    15361 caagagcaag ttggataaat cctgaggctt gcctttaaag taatcatcta agcaagcaat
    15421 aactgggtct aaaataggat gactaacaac ttcttctatc gtttcatctc ctagtcccct
    15481 ctcaaaatgc ttctgctcct gaacccaaat tccatacaaa taatggtcat cagctacaag
    15541 tgatagaata ccaattggtg aggagtagag tatttttaca tacttctttt gcattatttc
    15601 tttaattttt gataggccaa gcgttcgcca tctactggca ccttaccaac ttgtttaaaa
    15661 ccaagttttt caaaaatatg ttgcataacc ttgttttcag catgcgtatc tgagcgaaaa
    15721 tcaagataat caaaaccttc aatcaagccc tctaagaagg tttgagcaac tccttttccc
    15781 tgcacatctg ctgccacagc aatacggtga aagactagat actctgactc tccagcttgc
    15841 cagtttccct cataaatagc ttcataggcc tcctctggac tcttggtcac agcagcatag
    15901 gctagcagtt ctccctcttc caaggctacg taggcttgcc ctgagatgat atcatcgata
    15961 ataacatctg catttggata gccattttgc cactggtcac taccagcatc tgctaaacat
    16021 tttttggcat cctccatcac ctgcatgatg gcatctactt catttggaaa agctaaacga
    16081 atttccatct tttttcctca tttctgacta gtttctccca tcatagcata atttaagtat
    16141 ttctacaagc agttaaaact tgactttgtg tttttgttat tttataatct agttatcaaa
    16201 actatataaa aaggagttga aaatgaaaac taccttttcc tacccaaaat gggcagaaat
    16261 tccaaacatt gacctctatc tggaccaggt tttgctctat gtcaatcagg tctgcgcccc
    16321 tatctctcct aataaagaca agggcctaac agcatctatg atcaacaatt atgtgaaaaa
    16381 tggttacctg acaaagcctg acaaaaaaaa ataccaacgc caacagattg cccgtttgat
    16441 tgctatcaca accctcaagt ctgtattttc tattcaagaa atagcccaga cacttaatac
    16501 tctacaaact caagcaagtt cagaccaact ctacgatgct tttgtggact acatgaacca
    16561 aggaattgac ccagctaacc ctattatcca aaccagctgc caaaccgtta aactctatca
    16621 tcaaactcta gacttaatcg atcatactca agaggaggta atccaatgaa cactagtctt
    16681 aaactcagca aacaactcag ttttggagag gagattgcta atagcgtgac ccatgctgtg
    16741 ggtgcagtca tcatgcttat cttgctgcct atttcatcca tctatagtta tgaagcacac
    16801 ggatttttat cctctatcgg cgtttccatt ttcgtcatca gtctctttct catgttccta
    16861 tcatccacca tttatcactc tatggcctat ggttcgaccc acaaatatgt tttgcgaatc
    16921 attgaccatt ctatgattta cgttgccatt gccggctcat acacgcccgt tgtcttgacc
    16981 ttgatgaata actggtttgg ctatctgatt attgtcatcc aatggggaac gaccatcttt
    17041 ggtattctct ataaaatctt tgctaaaaat gtcaatgaga aatttagcct tgctctttac
    17101 ctgattatgg gctggttggt tctggctatc attcctgcca ttatcagtca aacgacaccc
    17161 gttttctgga gtctcatggt aactggcgga ctctgttata cagttggagc tggattttat
    17221 gccaagaaaa aaccttattt ccacatgatt tggcatctct ttatcctagc tgcgtccgta
    17281 cttcaataca tcgctattgt ttattacatg taaaaaagtt gagaaattca atctcaactt
    17341 ttttctttac acatattgat aaagtactgg tgcaagcgca catcatcagt caattctgga
    17401 tgaaaagaac ttaccaacat atttttttct tgggctgcaa caatttgatt gttcactgtt
    17461 gctagaattt ctacaccctc accaacacta ctgataatcg gaccacggat aaaggtcatt
    17521 ggaatcttgc caactccctt acattctgct tccgtgtaga aacttcctaa ttggcgccca
    17581 taagcattac gctcgaccac catatccata gttcctagat aactctcttt ctgagaagtg
    17641 atttccttag ccagcaaaat taagcccgca caggtcccaa acactggtaa gccagataga
    17701 atggcttctc ggatgagaag tagcatgttc tggtcacgta agagcttgcc catggttgta
    17761 gactcaccac caggcaaaat caaacccgac aagtcactct gatcttgctg aaaatcatct
    17821 agatttctga gttctacact ctcgacacct aattgatcta gcacttttgc atgttctgca
    17881 aaggcccctt gcaaggccaa tattccgatt ttcatctatt ttcctcgttc agccatgaga
    17941 atttggattt cattttcatt aataccaacc atggcttctc ctaaatcttc agagatttga
    18001 gctaggattt gaggattacg gaagttagtc acagccttaa caatggcact cgctcgttta
    18061 acaggatctc ctgacttgaa aatacctgaa ccgacaaaga ccccctctgc ccctagttgc
    18121 atcattaacg cagcatctgc tggcgttgca acacctccag cagcgaaatt tacaactggc
    18181 aattttccat gttcatgaac atattggacc aattctacag ggacttgcaa atccttggca
    18241 gcaacataaa gctcgtcctc acgtaagttt tgaatgcggc gaatttcctg attcatcata
    18301 cgcatatgac gaacagcttg gacgatatcc cctgtccctg gttctccttt ggtacgaatc
    18361 atggaagcac cttcagcgat acgacgcaag gcttcaccca aatccttagc accacagaca
    18421 aaaggaactt ggaattcttt cttgtccaca tggaaacggt catcagctgg agatagaact
    18481 tcactctcgt cgatataatc aatttcaata gcctctaaaa tctgagcttc aacaaaatgc
    18541 ccgattctga ccttagccat tactggaata ctaaccgctt cttggatttc cttaatcatc
    18601 tttgggtcgc tcatgcggga aactcctcca gctgcacgaa tatcagccgg aattcgttcc
    18661 aaggccatca cagctgccgc accagcagct tctgcgatac gagcctgttc aggattctgc
    18721 acatccataa taacaccacc cttgagcatc tgtgccaagt ttttatttag ttcataacga
    18781 ttttcagtca tttgttttat cctcatcatt tgtattggta gctacctttt cattttaagt
    18841 cagaacagaa tgaagcacaa gataaaaaaa ctataattgt atggggacaa attagctaaa
    18901 aactatctga ccttaactta aggccagata gctcattcat ttttattttt cagccgtaag
    18961 ggcagccatt gtgatgtagt tgtatggttt gttgaagtgt ggcaagaaga agaggtctgt
    19021 caatgccaat ttatcaattg tcacatgctc ttggatagca agtgagaaca tgtggattcc
    19081 catgctaatt gcaatatcat gtgaaaccat ttgggcacca agaatttcac ggctatcttt
    19141 gtcaaagaca atcttaattg ctacttcatg gttgtcatgt ttcatgaatt ctggtttttg
    19201 aagatcgtta aagcctgttt cagttgcgtt gtaaccagca gctttcgctt tttcaagagt
    19261 caaaccagtt gaaaccatgt gaagaccgta gattgagata ccatttgaac cttgaacacc
    19321 gattccttcc aattcatgtc cacaagcatt gtaggcacca acgataccag tgcgaacagc
    19381 atttgaagca agagcgatat agcttgtatc tttacgagca ttgtcataaa cagtcgcaca
    19441 gtcaccaaca gcgtaaacgc ctgggataga tgtttcttgt ttcttgtcta caaggaaggc
    19501 accgttgcgg aagagttcga tcttaccatc tgcaagggct gtgtttggac ggaaaccaac
    19561 tgcaaggata accatatcca cgtcaaagct ttctttgtca gtaatcaagc gttcaacttt
    19621 accgtcacct tcgattgctt taacagtttg acctagagcc aagcggatgt tgtgatcttc
    19681 caagttcttc gccatcattt gtgtgaagtc tttgtcatag taaccgttca agacagtatc
    19741 aacgatatca acaaggacaa cttcttttcc aagacgttca aaggcttcag caagttcaac
    19801 accgatgtaa ccaccaccaa caacggcgat acggtcgagg tgttggctct tgtcagaaag
    19861 tttattgata acttcttcag cattttggta caatttcacg aattgtacgt tttcaagagt
    19921 tgctttaaat tcgcggtttc ctttaacaat ttcaacacct tcgattggtg gcaagattgg
    19981 tgtagaacct gtagcgaaaa tcaatttttc gtatgattct ttgtgctctt ttccttcaac
    20041 ttccgctgta actactttgt tatcatagtc gattgaaaga acaggtgagt tcatgtaaac
    20101 tttagcacct ttagcttcca atttttcttt atcagaatag aacaagcctt cagcaccgtc
    20161 aatttgttca ccaatccaaa gagccattcc acatcctagg aaagagatgt tagagttttg
    20221 gtcaaataca acaatttcgt tctcatttcc aaaattatcc aacatggtat tgatacatgc
    20281 tgtaccagcg tggttagcac cgactacaac gattttactc ataaaaattt cctgccttca
    20341 ttctaaattt accttactag tataccattt accgttagcg tttacaaggg gggtactatt
    20401 atttcagcat tttttatcaa aaataattcc ccatttatcc tgttttcaag cctcatgaat
    20461 tttatgagca tatttcttga ctttttccaa attttgtttg tgaaaattct aactttatgg
    20521 tattataata acatgaaaat gaaatgtaag ggcttcaatt tagatgatta tttgatatta
    20581 caacttattt tctataagag aaaggagttg gtagcttgac tcttcgttca cattctgaac
    20641 ggctaatggg gactactatc actatttcat tagtggatga gcaagccgat atctttctcc
    20701 aaaaatcctt tgacttgctc aaagagcttg aataccgctt caacgccaat agtcaagaat
    20761 ctgagttgat ggaaatcaat tatcaagcag gaatatcccc cgtcacggtt catccagacc
    20821 tgtttgagct gatttcactt gggttagagc atagcctagc gctctctagc cacctcaata
    20881 tcagcattgg tcccttaatt caaacctggc gtatcggttt ttcagatgcc aaggtcgccc
    20941 agcctcaaga aattgaatcg gtgctgcctc taatcaatcc tcatggtatc gagttagatt
    21001 cttctacttc tactgtgttt ttaaaacaga aaggaatgaa gatcgatcta ggttgtttag
    21061 ccaaaggata cagtgcggat aaggttgccc aatttcttag gaaagagggg gtgacttctg
    21121 ccttgatcaa tctgggaggg aatatcctga ccattggaaa aaatcaggca agaggggata
    21181 acccatggca aatcgggatt caagacccag ccaatccgag gggaaatcat ttaatgacca
    21241 tccctgttgt caataaatct gtcgtgactt caggcattta tgaacgtcac ctgaccgtcg
    21301 atggacaaga ttaccatcac atttttgaca gtcaaacagg atatcctgtt gaaacggaac
    21361 tagcgagtct aacaatcatc tctgataaat cagtcgatgg cgaaatctgg acgactcgac
    21421 tctttggaga aagacctgct tctatcttct ggcaagtcga aagtttggag ggcatcgaag
    21481 tcatcctcat cgataaagaa ggccacctaa gctgttcttc aggaattcct actctataga
    21541 gacaactgtt tcaatggaat tttaaaattg tattatgtaa aaagagaaag gaaatctcat
    21601 gttaaaactt attgctattg ttggaacaaa ttcaaaacgt tctacaaacc gtcaattgct
    21661 tcaatacatg caaaaacact ttgctgacaa agctgaaatt gagcttgttg aaatcaaggc
    21721 cattcctgtc ttcaacaaac cagctgacaa gcaagtacct gctgaaatat tggaaattgc
    21781 tgctaaaatc gaagaggcag atggcgttat tatcggtact cctgagtatg atcactctat
    21841 tccagctgtt ttgatgagcg ctcttgcttg gttgtcttat ggtatttacc cacttttgaa
    21901 caaaccaatc atgattacag gtgcttctta cggtacgctt ggttcatctc gtgcccaatt
    21961 gcaacttcgt caaatcttga atgctcctga aatcaaggca aatgttcttc cagatgaatt
    22021 cttgctctca cactctcttc aagcatttaa cccaagtggc gacttggttg accttgatgt
    22081 tatcaagaaa ttggatgcca tctttgatga cttccgtatc tttgtaaaaa tcacagaaaa
    22141 attacgtaat gcacaagaat tacttcgcaa agatgctgaa gactttgact gggaaaattt
    22201 gtaagatagg agaccaaaaa gaatgaaatt tgttggactt gttggatcaa actacgatca
    22261 atcatataac cgtaagctct tggaatttat ccgtcgctac ttcaaactca aatttgaatt
    22321 agaagttctt gaaattgacg aagttccaat gtttaaccaa gatgaaaaat gggatgaaag
    22381 tttccaatta cgttatttat ataacaaaat tactcgtgca gatggtgtta tcattgctac
    22441 tcctgagcat aaccacacta tctcagcttc actcaaatct gtacttgaat ggctttcata
    22501 cgaagttcat ccatttgaaa acaagcctgt tatgattgtg ggtgcatcat actatgacca
    22561 aggaacatca cgtgctcaag ttcaccttcg taaaatcctt gatgctccag gtgttaatgc
    22621 ctacacgctt ccaggtaacg aattccttct tggtaaagct aaggaagctt ttgataacaa
    22681 cggaaatatc accaacgaag gcactgttaa attccttgaa acttgcttag ataactttgt
    22741 taaatacgta ggagtcgttt cgaaattgaa aaaaccaaaa ccaatcgaat cagaagactt
    22801 ggattgtgga aaaccaatcg ctacaaccat cacagaagtt gaccctgacg atccagaatg
    22861 ggtagaaaaa gttgcagcaa tcactggtgc tgtttctggt gatacctatg tcaaattgga
    22921 ccacggtatc ctaacagtta accaaattga tatgttcttg aaagctatgc catttgaatt
    22981 gacatacgct gacgacaaca accaattcct ctactacaac aacgctcacc aagatccaga
    23041 cactatgttc gctaaacgtg taccacctca atcaggtagc cgtatgtcga ctgttcatgg
    23101 ttctcttcca ccagcacgta tgaagaacgt agagtgggtt atcggaacac ttcgcaacgg
    23161 aaaccaagaa tacgtccgta cgatcgttcc aggttctcct gcaggtgtta tcaacactca
    23221 caactaccaa gcaatgtact atcctgatgg atcatacgct ggtatcaatg aaatcgtctt
    23281 taacttccaa ccatggcttg actggtacct aaaagagact ggtcaacgtt tggtgggtgg
    23341 tagcggacca tttgctcctg ctgccggagg tcatggagac gccgatgcta cttctggcgc
    23401 ttctgattca ggggatgctg gaggccacgg tggtgacgca gacgctacag ccggtgcaag
    23461 ttactaatga tagtttttag gaaccattat ggttcctttt tagcgaaaaa agactagcaa
    23521 acacaaactg ctagtctctt tgttatcgtt tcatctatct ttgttaaaag aaagaataca
    23581 tattatgaat ttggatcatc aagactacgg ccatgtaatc ctttttcacg ttgtacttgg
    23641 cgtagttttt ctggtgtaac atcgtttcct tcttcgtcca caattttgat tccttcaatg
    23701 tggtgacgaa cagcgcggcg ataaccttcg atgtactcct cacgtagttt ggcttgttcc
    23761 actttttctt ctggtgttaa gccttctgtt tttttctttt tagcaagctc attgatacga
    23821 gcaatttttt tcggatccat ttcttctcct ctgtaataag ataaagtccg tttatcaaat
    23881 tttatttagt gttaatttgg ttaaaacaag caaacttagc tgctttcttg gttagttgtg
    23941 acaagattgc caaacgattt tgacggacag cctgatcttc agccattacc atagtatttt
    24001 caaagaaagc atcaatgact gggctaagcg caaagagttg tttcaattgc tgacttgcag
    24061 gtcctgataa aacgagtgtt tctactgctt ctgccaaagc tttttcttgg tcattctcaa
    24121 atagtgctga atcaactgta gcaacccctt ctgccttctc agccaggtta aaggcacgag
    24181 aaagtgattc aacagatggt ttaaaatctt cttccttgct tacttctacg agagcacttg
    24241 ctgcttccaa catatctgcc acaacaaagt ttgaacctgc aagaactgct tccttgatat
    24301 cttttggagt agagcccatc atcttatcaa cacgagcctt gataaagtcc ataacctctg
    24361 ctttattttc ataagtcaaa ctgtcaaatt tcaatgcata aaggctatca atcagctcat
    24421 ccatagcaat gtgccaacca aaggcatcca agatacgaac cacaccttga gttgcacgac
    24481 gaagggcata agggtcatta gaacctgatg gaatcaatcc tactgagaag aaactcaaaa
    24541 tcgtatccaa tttgtctgca atggctagaa ctgcaccgac cttgctctct ggaagttctc
    24601 cttcagctga tgtaggcatg tagtgttcac gaatagcagc tgccaccgct ggagtttcac
    24661 cagcaagaag ggtgtatttt tcacccataa ttccttggag ttcgtcaaat tcaccaacca
    24721 tacctgtcaa caagtcaaac ttgtaaatgg ctgctgcacg agcaaggtca actgtttcat
    24781 ccactgacaa accagctttt tctgccaaaa gtacagtgat ttgacccgta cgaatcatgt
    24841 gttcacgaag ggaaccaatc ttctcatgga aggtgacatt gtttaatttt tcaacaagat
    24901 ctgaaatcac caatttttgg tcttcacgcc agaagaattc tccgtcttcc aagcgggcta
    24961 ccaagacttt ttcatttcct ttgatgacat ttttcaaacg ctctgcgttt ccgttacgaa
    25021 cagaaatgaa gtttggcaag agttttccat cttgatcacg aacaacaaag taacgctggt
    25081 gttccttcat agaagtcacc aagacttctt ctggaacttc aaggtattta gcatcaaaac
    25141 ttcccatgaa ggcagttggg tattcaacca aattcaagac ttcattcagc aaatccgcat
    25201 caatttcgat acgtacacca tgttttgcct caattttctt gatttggtca acaatcattt
    25261 gctcacgttc acatggatct gcgattacaa actgcttacg aaggtcttct tcatagctca
    25321 atgctgactg aattttggtt tctttcccca agaaacgatg gccacggctc acacgacctc
    25381 ccttgatatc aaggaaatcc aagtcaaact cttgctcatc caagagaaca gttaaagtgt
    25441 gaacagggcg gatgtattca aagctatttc cagcccagtg catgctgaca gggaaagtca
    25501 atgacttcaa gacatctaca acaccaggaa caatggcttc aactgcttga ccaacttctt
    25561 ccttagtgac atagacatat tcttcaccct tgatttcacg gaattcgata tcttcaacag
    25621 tcaagccttt tccacggaca aatccttgag ctgctttggt gaagtttcca tcactatcca
    25681 aggcaatttc ctttgctggt cccttgaaat cttctgtcaa atcagactgt ttgtctgata
    25741 aaccagtcac acgaacagcc aaacgacgtg gtgttgagaa ggtttgaatg gcttcaaaag
    25801 acaggcggtt ttccttgagg aaggctgcca ttttttcgcc tagttgtttt tcacttggtg
    25861 tgacaacata ggctggtaat tcttcaagac cgagttctac taataagttt tttgtcatgt
    25921 tttttctccg aaaagtatct ttttattttc cagtttgcct tatgtgattg gcacgcaagc
    25981 aaccaacttc gttgtttcat tgctaaaatt ggagccaaaa gtctccaatt ttgcctagta
    26041 tccttagttt cactaaggat accttcatca ctgcggcaac tgactcaggg ctcactctgt
    26101 tcgcccattt tcgtaatttg tcactctctt tattctgcgt cttctgctag gagtttagct
    26161 cttgtttctt catccaaaag tgggtaacct aggcgtttgc gttctgcaac aaaggttttg
    26221 gctacaacac gggccaagtt acggatacga gcgatatagc ctgcacgctc tgttacagat
    26281 acagcaccac gcgcgtcaag cagattaaag gtatgtgaac atttgagaac atagtcatag
    26341 gcagggtgta ccaagccttc ttctaatgca cgaccagctt ctttttcaaa cttatcaaag
    26401 ttttcaagca acatttcttg gtccgaaatt tcaaatgaat attttgagtg ctcatactca
    26461 ggctggataa agatttctcc gtattttaca ccatcagccc actcgatatc atagacagag
    26521 tctacttctt gaatgtaaga agccaagcgc tccaaaccat aggtaacttc cgcagtcaca
    26581 gggccagttg ccaatccacc gacttgttgg aaataagtga actgagtgat ttccattccg
    26641 tcaagccaaa cttcccaacc aagaccagct gaaccagttg atgggttttc ccagttgtcc
    26701 tcaacaaaac gaatatcgtg ctccaaagga ttgattccca atttttccaa agactcaagg
    26761 taaagttctt ggatatttga tggagaaggc ttcatgacca cctggaattg gtggtgttgg
    26821 tagagacggt tagggttttc cccataacga ccgtcagcag gacgacgtga tggctctaca
    26881 taagctgcat tccatggctc aggtccgata gcacgaagga aagtgtaagg actcattgtt
    26941 cccgcacctt tttcattatc ataagcctgc ataagcatac aaccttggtc attccaaaat
    27001 tgttgcaaag taaggatgat ttcctggaaa gtcaatttct tagacattgt ttactccttt
    27061 ttatataaat tacttgcgac atgagtctgc ctcgtcgatc atacgaggca agacgagtta
    27121 gtactgcgtc tagctcaggc actctagtgc tgagcgtggg gcagtccgac tgtaaggagg
    27181 tttctgccac tgatgcagta aaatgttaat ttcttagaca ttgaatactc cttaataaaa
    27241 aatgatttct tgcgacacga gtctgcctcg tcgattatac gaggcaagac gagttagtac
    27301 tgcgtctagc tcagcaccct agtgctgagc gtggggcagt ccgactgtaa ggaggtctct
    27361 gccactgatg cagtgaaatg ttaatttctt agacattgtt tactccttta gtttttatat
    27421 ttctttttca attaatttct gctgaacaaa ccaatctaac aagggaaaaa ttttttctgt
    27481 atttgcccat aaatgataag aatctaagac cgcttgtaca ctacctaaat tttctaccaa
    27541 cttatctact gtcaaaaagc ttcgccagta ttcataaaaa atacttgcat agttcttatc
    27601 ataagtcgaa gaaccaaaat cattcaatga atgccaacca tacttcttct gaaaaagttc
    27661 tacgagagat tgattacaaa ttttttccgc ttgaaattcc tcttctgtaa agaaatactt
    27721 gcgactaata tattcaacca tcccctcttc gaaccagata taagagtcat aaccatcaaa
    27781 atcatctaaa aaatgctccg accaatgagc taactcatgt cctacaatct gtaagaggaa
    27841 attttcagat aaagaatgat agtgactttc tattgcttga gtttgctcag aacactcgta
    27901 gtccatcaat tgatacaaat acaactcttt ccaaacagct aaatcaggcg ccataaccat
    27961 tcgtctatta tttgtatagg ctggaacagc gctttcccta ataatctgtg tagcagcatt
    28021 aaaatctgac caaataacgg cttgcggtaa atcacagact gcaagttcat tctttaaaaa
    28081 agattgataa tctttcaact tttcagtatt tcttactaca aaatcacgaa atgtagctag
    28141 ttgactatcg tcttttacaa gataaaggtt gtccacggct ctcctttctt tcacacaata
    28201 gactgaataa gcaaaagaac cgcgtccgac aatcctaggt tgatttaacc taggggcgtc
    28261 agaaacgcgg ttccacccta atttattact tcattgtttt tgaaaatact acagaaagcg
    28321 ccagctcatt attttgccct acttggctcc cactatccca agctcgcttg aagaacgcca
    28381 taagactttc tttcctgctg actattatat caaaaattag aataatgtac aattcttttt
    28441 atgattttct agaaatccac atcatcaact cgtggagcac ccgattgaac agcaatcgtt
    28501 tttaaggttt ctctctcctc atgactcagt tcaattccaa agcaatcaag attagcttga
    28561 atacgagagg ttgtgacaga ttttggaagt ggtaaaaatc cttctgccaa gctccaggcc
    28621 aaggctatct gagcaatcga ttttccgtga tttgctgcga tttcttgcac ttgcttgcta
    28681 tcaaatagtt ctccctgacc aaaaggcccc caagcttcca ataaaattcc cttttcacga
    28741 cagtaagcta cgacttgatc ttgatacaca cctggcgcca agcgaacttg attgaccgca
    28801 ggaacgatag ttgcagtttc aagcaaggca tccaaatgat ggggaagaaa attgctaacg
    28861 ccgatagcac ggattttccc ttcttgatag aggtcttcca tcgctctcca aacttccgca
    28921 ttgcgagttt tccatgcgtc attttctctg agcggttttg ggttcggcca atgaatcaaa
    28981 tacaaatcca aataatccaa gcccagtttt tctatagatt tttccaaagc ttgacgagtt
    29041 tgctcatagg tttgctgact attccaaagc ttggtagtta cgaacatttc ttcacgtgga
    29101 actccgctat ctttgattgc ttgaccaaca ctttcttcat tctgataaat cgccgccgta
    29161 tcaatatgac gataaccagc cttcaaggct tctaacactg catgataggc ttcttctcca
    29221 tccttagcct taaaagttcc aaatcccaat actggaattt ctactccatt atttaattga
    29281 taggtattca tatgcttctc cttctatttt attcatcaat tatagcataa gacatttttt
    29341 aagtagtact atcttctgta aaaaataagt ctgtcaaata tctaacagac ctattttttc
    29401 ttgcttattc atcacgacta tagtacagct catgagcttt taggcgagta ttgagcatct
    29461 ctggtatggt cacaaaggta taaccttgat ttttcaaata ctcaatgacc cttggcaagg
    29521 cattgactgt cggactgtga atatcatgca tcaaaacgat agagccgtta gctacttgat
    29581 gctgaatttc tgtcaaaata gatgcttcat ttttactctt ccagtccaga ctatccacat
    29641 cccacatgat aaagctcaaa tccaagctat tgcgaatatc atctgtaata gcaccataag
    29701 gtggacgcat gagtttagaa ctagaaccca gcactttagt tagcacatcc tcagtatcag
    29761 taatctgctt tttagcttca tcaagagaga gttgcgagag aatcggatgg ctccaactat
    29821 ggtttccaac aacatgacct tcagatttta tcctcttcac caagtcctca ttcccagaaa
    29881 catttttccc aagcacaaag aaagtcgctt taatatcata tttagctagg gtctctaata
    29941 cctgcggggt cgttgctgga tttggaccat catcaaaggt tagagcgaca actttttgat
    30001 atttcttatc aaagtaagat tgatacaagg ccgcatcttt ttcgagtaag tacgaagatt
    30061 ggataacatc aaagaaagca gatactggca aggctatctc ttctaaattt tcaagcacag
    30121 gacttgaata aaggataatc tgactatcct tgtaatcaaa attccatgca gacaagtctt
    30181 ggtcagagaa gctttttaca atctgctcac tctggtcttg ctctattttt ttatcctcta
    30241 tgaaggaggt caactctttt atcagctgtt ccttagcctt actagcatct gaaaacagtt
    30301 ggtcaagtgt aaaaggttgc ccatcttctg ttaagtgaac ctttcctaga ctggtctttt
    30361 cagtctcttc aaccttaaaa gcaactaaat catagatttg tttggtcaca ttacgattaa
    30421 cgactccctt taaacctgac tcttcttgct ctgtatagta gaaaacaaga ttgtccttac
    30481 tttctagctt gtccttaaca tcttgattta tcaactccct aacagaggaa atcactttct
    30541 ccccttggag aggataatag gcaatcactt cggcttgccc ctgacgaaaa tgctccttct
    30601 gatttccctc actcaattga tcatctttct cttttttgag cgattcaatc ttttgctcaa
    30661 aacttttttg ctggtagatc ttaaaagcaa taaatccgcc taataggcaa atagaaattg
    30721 ctaagatacc aatcaaagcc aataatacat gtctcgtttt cccgtgtctg ccacgtccta
    30781 gtctactttt attcatattt atatcataac aaatttgagc aataatttca atgatacaat
    30841 ttggcaatcc acaattcctc tagcaagcca aagcatctta catcaactcc aacatccgta
    30901 tctgtagaga ttatgtagtt ttctatctat ggaatttcta gtaaattgaa gctagaatag
    30961 tagacctata cttctaaaac attgttagaa atcgatttga ttgtcctgat cgatttgtcc
    31021 tgttcttatt tcattttact ataaaactat gaaaagctag gtcatctgag aagtaattac
    31081 tatcgacaat tgcgatagcg tatactggtg cgatttgttt gtagctctgg tgggtatcac
    31141 cttcacgttg gcgaattttt tctaggtttt gattaacctg actgcacaga taagcccata
    31201 ggcgattgat gaaaaaattc tgatgatgaa cctgaatttc gatgataact tgaattccat
    31261 tatctaactc cgccaagacg tctatactag tatagaaatc ctgcgctgag taggacatgg
    31321 aaggcaagac gtgaatgtta cttccctcca aaatcgtcac attttttgct ggcaagtcca
    31381 gcatatcgcg gataaattga caaatcatta gttgggctga tacccggatg tctgagaatc
    31441 ctccttttcc tccttctatt atagcacatt tttaaatcta ggtttgctag attctatgct
    31501 tctatctatt tattcggaaa agaaagcttt tcttcagaag aaagctaata gcttatttga
    31561 aattttctcc tctctgttgg atagtcccgt ctatctatgt tataatgaaa gaaggattta
    31621 aaatcggaaa aggagtattt atgctaaaat taggtgtcat cggaactggc gctatcagcc
    31681 atcatttcat agaagcagcc cataccagtg gagaatacca actggtcgca atctattcta
    31741 gaaaactaga aactgcagca acctttgctt ctcgctatca gaatatccaa ctattcgatc
    31801 aattagaagt cttcttcaaa tcttcttttg atttagtcta tatcgccagt ccaaactcct
    31861 tacattttgc tcaggcaaaa gctgccttgt ctgctggtaa acatgttatt ctcgaaaagc
    31921 cagctgtcac tcaaccacaa gaatggtttg atttgattca aacagctgaa aaaaataact
    31981 gttttatctt tgaagcagct cgtaattacc acgagaaagc ctttactact atcaaaaact
    32041 ttttagcaga taagcaagtg ttaggagcag atttcaacta ttccaaatac tcttccaaga
    32101 tgcctgactt gttggctgga caaacaccaa atgtcttttc agaccgtttt gctggtggag
    32161 ccctcatgga tttggggatt tatcccctct atgctgctgt tcgtcttttt ggaaaagcca
    32221 atgacgcgac ttaccatgct caacagcttg acaatagcat tgacctaaat ggagatggta
    32281 ccctcttcta cccagactat caagttcaca tcaaggctgg aaaaaacatc acttccaatc
    32341 ttccttgcga gatttataca acagatggaa ccttgactct caacacgatt gagcatattc
    32401 gctcagctat ttttaccgac caccaaggaa atcaagtcca gcttcctatc caacaggatc
    32461 ctcatacgat gactgaggaa gtcgctgcat ttgcacacat gatccagcaa ccagatctga
    32521 atctctacca aacttggctg tatgatgcag gctctgttca tgagctacta tataccatgc
    32581 gccagactgc tggcattaga tttgaggcag aaaaatgaaa accaaactac cgactgaatg
    32641 gcaagaactg agtgaccaac tcggtttcca agaattcacc ctcattcaaa ctcaactatt
    32701 tgagcccctt cttgctggag aaaacctcct aggagtgagc caaaccggaa ctggtaagac
    32761 cctagcgtat ctcctaccaa gtcttctcag actacaaaag aaaaaagccc aacaactctt
    32821 gattctagca ccaaatacgg aacttgctgg acagattttt gatgtatgta aaacgtgggc
    32881 agaagctatc ggattgactg ctcaactctt cctttcaggt tcaagtcaga aacgacaaat
    32941 tgaacgcctt aaaaaggggt cagaaattct gattggaact cctggccgta tctttgaact
    33001 cattaaactt aaaaaaatca agatgatgaa tgtggaaacc atcatcctgg atgaatttga
    33061 ccaattacta gatgattctc agattcactt tgtagaaaaa atcactcact acgcacctcg
    33121 tgaccaccaa ctggtctaca tgagtgccac gaccaagttt gaccaagaaa agattgtgcc
    33181 gaatacacgc actattgatc tctctgatca aaaattggac aatatccagc atttctacat
    33241 gcaggtagac caacgtcatc gagtggatat gctacgaaaa ctggctcatg tagaggattt
    33301 ccgtggtcta gtcttcttca atagcctgtc agaccttggg aatgccgagg aaaaactaca
    33361 gtatcgtgat atattggctg tttccctcgc tagtgatgtt aatgttaaat ttagaaaaat
    33421 catcttagaa aagtttaaag ataaccaact aaccctgctt cttgcaactg accttttggc
    33481 tcgtggaatt gatatcgata gcctagaatg tgtcgtaaac tttgatattc ctagagatag
    33541 cgaaacctac acacaccgtg ctggccgtac tggtcgtatg ggcaaggaag gttatgttat
    33601 cactctcgtc actcatccag aagaaatcaa aaaacttaaa aagtttgcaa gtatccgaga
    33661 aattgtccta aaaaaccaag aactctatat caaataaagc cctattgctc tatacacatc
    33721 cagtgtatgg agctttttta taagcaattc aattttatac tcatctgctt tcaaaaagca
    33781 ttctagtcca tttccgatta acgatggact ttatcacctc cttctccagt ccttgtatga
    33841 catcttccaa agttcgaaag gctttattct taaatccacg tttacgaatc tctttccaca
    33901 cttgttcaat ggggttcatc tctggtgtgt atggaggaat aaatgcaaag ccaatattag
    33961 tcggaatctt taaggtactt gatttatgcc atatagcatt gtccataacg agtaaaaaat
    34021 aatcatatgg ataagcttgt gaaagctctt ctaaaaagac gttcatccac tcagtattac
    34081 atccaccagc tattaagaaa aatgattcgc ttgtataggc atcaacagct ccataacaat
    34141 agcgaaattc tcgtatatag tgactatgga catgtggacc tactcctatt ggagaccaac
    34201 aagatcccag tttactgatt ctaccgaaac cagcctcatc ttggtacatc aagcgaacct
    34261 tatgaaaaca tctactagtt ttaaagcgct ttcttgtctt cttgaattga gattttattt
    34321 ttagacgcga caatggtttg agcgtctgct ttcctaggat gttctggacg tggcataata
    34381 tttcgccaac catggcgctt caacagttga tagaaggcat cacgtgtgta ggaacgacct
    34441 aactcctttt tataagcctg aaataaggca tcaattgtaa caaattctcc tgcctctgca
    34501 gccttcaaat ggcgggca
//
LOCUS       DAVHLA010000019        34313 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVHLA010000019 DAVHLA010000000
VERSION     DAVHLA010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34313
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.019"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(175..1161)
                     /locus_tag="VVO77_001061"
     CDS             complement(175..1161)
                     /locus_tag="VVO77_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU5693082.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(1171..1971)
                     /locus_tag="VVO77_001062"
     CDS             complement(1171..1971)
                     /locus_tag="VVO77_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEU5693083.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(2224..3066)
                     /locus_tag="VVO77_001063"
     CDS             complement(2224..3066)
                     /locus_tag="VVO77_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU5693084.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(3068..4360)
                     /locus_tag="VVO77_001064"
     CDS             complement(3068..4360)
                     /locus_tag="VVO77_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU5693085.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(4471..5742)
                     /locus_tag="VVO77_001065"
     CDS             complement(4471..5742)
                     /locus_tag="VVO77_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU5693086.1"
                     /translation="MSSKFMKSTAVLGTATLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            6291..7808
                     /gene="malQ"
                     /locus_tag="VVO77_001066"
     CDS             6291..7808
                     /gene="malQ"
                     /locus_tag="VVO77_001066"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEU5693087.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            7834..10092
                     /gene="glgP"
                     /locus_tag="VVO77_001067"
     CDS             7834..10092
                     /gene="glgP"
                     /locus_tag="VVO77_001067"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEU5693088.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYKVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIDLDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINSNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(11137..11709)
                     /locus_tag="VVO77_001068"
     CDS             complement(11137..11709)
                     /locus_tag="VVO77_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693089.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     SAMNLLSPGTYLTQLWDKNDAIPNNGRINF"
     gene            complement(12334..13182)
                     /locus_tag="VVO77_001069"
     CDS             complement(12334..13182)
                     /locus_tag="VVO77_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEU5693090.1"
                     /translation="MNTNLKPKFQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            13334..13612
                     /locus_tag="VVO77_001070"
     CDS             13334..13612
                     /locus_tag="VVO77_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693091.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            13614..15677
                     /locus_tag="VVO77_001071"
     CDS             13614..15677
                     /locus_tag="VVO77_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEU5693092.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(15755..17011)
                     /locus_tag="VVO77_001072"
     CDS             complement(15755..17011)
                     /locus_tag="VVO77_001072"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEU5693093.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            17153..19618
                     /locus_tag="VVO77_001073"
     CDS             17153..19618
                     /locus_tag="VVO77_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEU5693094.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLCFLGGMLGVGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLATADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            19683..20594
                     /locus_tag="VVO77_001074"
     CDS             19683..20594
                     /locus_tag="VVO77_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEU5693095.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            20824..21522
                     /gene="dapD"
                     /locus_tag="VVO77_001075"
     CDS             20824..21522
                     /gene="dapD"
                     /locus_tag="VVO77_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEU5693096.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            21590..22720
                     /locus_tag="VVO77_001076"
     CDS             21590..22720
                     /locus_tag="VVO77_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEU5693097.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDDAFGDWLPDQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            22732..23271
                     /locus_tag="VVO77_001077"
     CDS             22732..23271
                     /locus_tag="VVO77_001077"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEU5693098.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERLLHHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMEFVAYDPQQLVKTSFALLEPQ
                     GDVEVVDASQIDLIHVPGLAFTTKGYRIGYGGGYYDRYLEHFSGRTLSTIYPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            23255..23932
                     /locus_tag="VVO77_001078"
     CDS             23255..23932
                     /locus_tag="VVO77_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEU5693099.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(23999..24898)
                     /gene="galU"
                     /locus_tag="VVO77_001079"
     CDS             complement(23999..24898)
                     /gene="galU"
                     /locus_tag="VVO77_001079"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEU5693100.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYKRTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFTGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(24920..25936)
                     /locus_tag="VVO77_001080"
     CDS             complement(24920..25936)
                     /locus_tag="VVO77_001080"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEU5693101.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKNVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            26148..26588
                     /locus_tag="VVO77_001081"
     CDS             26148..26588
                     /locus_tag="VVO77_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU5693102.1"
                     /translation="MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRP
                     TLTKLKYIAERLEVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETIAQKKESVFDK
                     IFEEYYDRLPEEERFIIPNYSYLALANYTVQKLPEKLVEILSFW"
     gene            complement(26711..27127)
                     /locus_tag="VVO77_001082"
     CDS             complement(26711..27127)
                     /locus_tag="VVO77_001082"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU5693103.1"
                     /translation="MTNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTA"
     gene            complement(27195..27845)
                     /gene="phoU"
                     /locus_tag="VVO77_001083"
     CDS             complement(27195..27845)
                     /gene="phoU"
                     /locus_tag="VVO77_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEU5693104.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(27860..28612)
                     /gene="pstB"
                     /locus_tag="VVO77_001084"
     CDS             complement(27860..28612)
                     /gene="pstB"
                     /locus_tag="VVO77_001084"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU5693105.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(28614..29429)
                     /gene="pstA"
                     /locus_tag="VVO77_001085"
     CDS             complement(28614..29429)
                     /gene="pstA"
                     /locus_tag="VVO77_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEU5693106.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDIMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(29422..30285)
                     /gene="pstC"
                     /locus_tag="VVO77_001086"
     CDS             complement(29422..30285)
                     /gene="pstC"
                     /locus_tag="VVO77_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEU5693107.1"
                     /translation="MIKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(30403..31281)
                     /locus_tag="VVO77_001087"
     CDS             complement(30403..31281)
                     /locus_tag="VVO77_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HEU5693108.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLIMEKLAEAYKKENPEVTIDITSN
                     GSSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAE
                     LADVFSGKLTTWDKIK"
     gene            complement(31448..32779)
                     /locus_tag="VVO77_001088"
     CDS             complement(31448..32779)
                     /locus_tag="VVO77_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEU5693109.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(32780..33487)
                     /locus_tag="VVO77_001089"
     CDS             complement(32780..33487)
                     /locus_tag="VVO77_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU5693110.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(33571..34056)
                     /locus_tag="VVO77_001090"
     CDS             complement(33571..34056)
                     /locus_tag="VVO77_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEU5693111.1"
                     /translation="MAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALY
                     TSIYFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQL
                     HYCVPKGTIWGSTVDKDDALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTR
                     Y"
     gene            34042..34313
                     /locus_tag="VVO77_001091"
                     /pseudo
     CDS             34042..34313
                     /locus_tag="VVO77_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
BASE COUNT        10130 a         6469 c         7347 g        10367 t
ORIGIN      
        1 ggctagcttc ctagtttgca ctttgatttt cattgagtat aaaaagatct tgggtaacaa
       61 ctcaatttca gtagaaaagg aagtaaatct tcccacaata aaacgcatag tatcaagttt
      121 tttcaatacc tgatactatg cgtttttgct tttaacgact ttttgcccag tctcttattt
      181 ttcgataatt ttgtgggcga tcaattgacg gtaacaaatt tgtttattgt ttttattatc
      241 attaataatc tggagaatag tttcaaggga aacacgacca agctctaaac tattgatatc
      301 gacataggct gccaagttga gcttgggatt aaccgagtca aagctgagaa cagggacatc
      361 cagctggtgt ttggcaatat agttacaaac accttcagct aggaggctat cggttgtgat
      421 gatagcatca atttgtggat cgtgcttgaa taatcgcttg ctaaatttat agcccttttc
      481 ttccagaaac tcgtcggcaa agtagatgcg attgttgtca gtggtaagtt tgtaatgttt
      541 aagcgcctgt tcatagcctg ttaaacggtc tttggtcacg aagagctttt tacttcctcc
      601 gataaaggca atgcgtttgc agcctttttt gatgaaatat tcagtcgcat caaaaccagc
      661 ttgaacattg tcgttgtcga caagtgggat gaaaggagat agagatttac ctaagataag
      721 gaaggggaac tgttcttctg cgacgagttt tacgagaggg tcttcttctt gggcatagag
      781 aaagattagc ccatctacac gcttgccgta gaccatttgt gaaatagcgt tgagacgctc
      841 cttctcatct ttccctgttg ctatctgaat ggcatagtgg ttttcagatg cgacttgaga
      901 gatgccacgt agaaccgatg gaaagaaagg attctggtag aaggcgtctg agtcatcagg
      961 aagaactaat ccgataacct gagtatagct gcttaccaag ctacgagcgt tgaggtttgg
     1021 gtggtagttg agttccttca tagctttgcg aacgcgtttt tttgtttcgt cgctaatggt
     1081 tgatttattt tgaataacac gggttacggt tgaaggcgaa acaccagcag ccttggccac
     1141 gtctttaatc gtaacgggca taaaaatctc ctatttatgg taatttggat cacggaaatg
     1201 tgttttataa aagatagtga ccagatacag aacaaaaaga atattttgta cagtaatcag
     1261 ggttgtcata ttttggccaa ataatcccaa aataagtgta atcagagtcg gcaatcctaa
     1321 acagttcaag ataaagtgat agcactcttt aaaggttcta aatgaaaaga ggcgtgattt
     1381 cttagtgata taaaggagaa gactagctcc tagagagacg ataaagaaat tcaaaccaaa
     1441 gaggaagctc gcaccgagaa ctaggaagag gctgatatag acacgatttt gttggtacca
     1501 gtctttagaa attgcttggg tcaagctgtc tttgcttttg aaactctcag tctgaatggc
     1561 tcggtaagag atgcgggtca gttccttgct ttccttgctg atgactagct catttgtatc
     1621 gaaatgcagt tgcaagtcct taggtaattc cttgatttga cttggaccaa tcacaacaga
     1681 aggggcttga ctagctgttc cagtataagt taatgtgcca tcgacaattg tagcatgttc
     1741 agagagatcc tggacaacct catttgtcag aggttcatag acattatcga taaaagtttc
     1801 tagcggatag gtctcctggg agctgttttg gatagcaatg ggtaccatag acaagctgat
     1861 aaggaagata ctggtaaaga gaagttgaaa ccagttgagc tcgaaacgtt tggacagggg
     1921 cttacgaaac ccccaaatac ttgaaaaata ggaaaatgga tatggaagca taggtatctt
     1981 tctaaaaggt gttttctata tgagtattat tatatagaga aatgctcttt atttcaagtc
     2041 taggagaaaa attgcttgct acaaggatat tatttacagt gacaattgct aataatcaat
     2101 gaaaatcaaa gtgcaaacta gccacaggtt gctcaaagca caactttgag gttggagata
     2161 aagctgacgt ggtttgaaga gattttcgaa gagtataaaa tgaaaaaggg tggcggggat
     2221 aaattatccc ttgtcgccac cacttgtaag tcctgaaaca aagttctttt gtaggaagaa
     2281 gaagagaata cagattggaa gggcgatgag gatagcacct gctgagaagt aggcaatctt
     2341 caagtttttc gcattgttaa cgaaggtttg gagacctacg gcaacagtaa agtattcttt
     2401 ctcacgaagc aagaaactag agaggatgta gtccccgaaa ggtcccatga aggcccagag
     2461 agcttgtacg gcaaccattg ggcgaacaag tggtagaaca atttgccaga agcggcggaa
     2521 gtgtcctgca ccgtctagtt ttgcagattc gtctaaagac attggcactg tatcgaagta
     2581 gcctttcatg agccaagcat tcatcgggat accaccacca acgtagagga agatgaggaa
     2641 ccagttgtgg ttaagggcgt tcaacataag cgccataacg aagaaggctg tcaaagcggc
     2701 catagttggc accatttgga tgatcaagaa gaagaccaaa ctttgtttac gagccaagaa
     2761 gttgtaacgg ctgtaggcat aaccagcaag tacgatgata cttgtttgaa cagccatggt
     2821 aattaaggcg ataatcaaag tgttgaggta ccaagtaccg tacaaggttt cagtgaagag
     2881 gcctttaaag ttatcaaaat tgaggtcgat attagtatct agtttaaagg ctgagacgtt
     2941 acctgcttta aaggctgaca taatggtaat caacagtgga tagataatta caattgatag
     3001 accaatcagg taaaggtaag taaggctttg agtcagtcta cgtttgagtt taattgagtt
     3061 attcatctta gacgtcctcc atatcaaatg cgtgtagttt cttgaatgcg atcatagaga
     3121 ttgagatgac aatgatagag ataatcaagg taacagctgc cgccattgag tattgaggag
     3181 atgtacctgt tgtcaaacgg tagatccatg agatcaagat atcggttgaa ccagctccac
     3241 ctccgacact accaggtcct ccaccattga agaggtacat gatagagaag ttgttaaagt
     3301 tgaaggtgta ttggctaatc aaagtaggtg ccgcaacagc caaaatcatt gggaaagtga
     3361 tgttgcggaa tttttgccaa gcgttggcac cgtcaatata agctgcttcg taaaggtcgt
     3421 taggaataga ttgcaagata cccaaagtca aaacgtagat gtatgggaat ccgagccaac
     3481 cttgcatcat aatcaaggca atcttagtcc aagttgggtc tgttttccaa ggaataagag
     3541 ctccatcaag gaaaggaagg aatttagcca agattggcaa tacttgagtg ttgatagcac
     3601 cgacactatc gttaaacatg tttgagaatg tcaagatagt gatgaaggct gggacagccc
     3661 aaggaagaag gaaaataaca ccaaagatac gttttccttt gataaatggt tggttggcaa
     3721 tgatagctgt gaagatacca attacgattt gtaaagtaga agctgccaaa gcccaaatga
     3781 tagtccaaga aagaacagaa ccaaaggcag aacggaaggt actcaagctc caaatgtttg
     3841 taaagttggt caaaccaacc cagtccaaca acttgtttgg tggcaagtgt tggaagtcgt
     3901 agttggtaaa ggcgatcatc aaggttacga taactgggaa gataatcgcg aaggtcatgg
     3961 caacataaga tggaatgatc aagaggtaag ggaagccatt ttcataaatc cctttgatca
     4021 tgtctttgag tgtgcgtgga actggaattc cattgttaat gcgttttgca atcgtatgtg
     4081 catctttgat atttgagaaa taaaagagta cataaacgat tacaaagatt agatggaagg
     4141 caccacgaat cagcataaag agggaattat cacgacctgg tttgtcacca agagtgatga
     4201 ggttgctcaa ttcaggggtt gcaagtgcta ggaagtaaag gacaaatacg atggttacac
     4261 caaggaagat aaaacctttg gctttttgtt tattgtaaat ctgtcctaac ccaggaatga
     4321 tagacagcag ggctgcttta ctaggttgtt gcttttccat attaactcct ttcataggat
     4381 actacttttt tataagaaag ctaaattatt tgtgtctcta ttgataaatt caaaggggga
     4441 tttgatttcc accccccttg aacaaatttt ttattcacca aatttttgtt tgattgtttc
     4501 tttgatcaat gttacagcat cgttagcagc tgttttagca tctttttgac cacttacagc
     4561 atcaaagagc atatttttcg ctggatccca aactgcagac atttgagaga tgtttggcag
     4621 tggttgagtg ttcttgaact gtttgataac agctgttgtc aactcatcgt ttttaccttc
     4681 agcgtatgaa cgagcctcag tattagctgg gatttcgtta gtcttatcat ataatacttt
     4741 ttgttgttca gttgcaacaa ggaagtctac aaatttttga gaagcttcaa ggttcttaac
     4801 ggcttgagga atgacccaag ctttaccacc accgaatgca gcatattctt ttccatttgg
     4861 aagagttggg atagttgcaa ctccgtagtt tactttagca tctttaaagg cttgagcttt
     4921 ccaaggtccg tcgatgatag cagctgtttt accttcttgg aattgagttt ggattaagtt
     4981 tccagcacct tctgtatctt gcataccttt aggccatttt tcgtaccaag atttagcgta
     5041 gttgatacct gcgatagaac cgtcgtttgc aagaccgatg tctttagcgt ctttaccgtt
     5101 ttggccaaag acgtaagcac cgttaccggc aagaagtcca tatgtatagt agaagtttgt
     5161 ccagtcagct aggaaggcag tagttttacc atcttcacca gcgaatgcgt atttgctatc
     5221 tttagcaagg ttttccaagt cagcaaatgt ttttggagca tctttcacca agtctttgtt
     5281 gtagtacata acaagtgact cgataacggc aggagcaccg taaactttac cattagcagc
     5341 tgttacaaga gatttagttg tgtcgtctgt tttagcacca tcgctcaatt tcacttctga
     5401 aagttgtccg tcagaaccaa ggctacctac acggtcgtat ggagccatca taacatcagg
     5461 gacattacca gattggttgt caagagaaag tttatcaaga cctcctagag catcaccagt
     5521 tttaagagtg acttttactc cagcttcttt ttcataagct ttagcaacct cttcaatata
     5581 gctcttatat ccctcgtcta catatacagt gagttctttg acttcagatg aaccagaatc
     5641 agcaggctta tcagcagttt tgcttccgca agctaccaaa agcaagctag caagtgtagc
     5701 agttccaagc accgcagtgc tcttcataaa tttagatgac atagtgtatt cctcctaaag
     5761 aatagcaagt tttattgata aggaaacgca aacgttttcc tttatgagct tagtatagca
     5821 caaatagaaa acggttgcaa gtattttttg taaaaatttt aaaaaatttt taagcttgat
     5881 ttgatagtat aattttgcat tttaatagaa gaaaagtatg aaatagataa gaatacagta
     5941 tttttaataa aaatatatgg aatctgtcta aagagggaaa tcaggagggg tacctccctg
     6001 tttctaatct atatctattt tctatagacg tttgtgcttt gttgcatata aattcaagct
     6061 ccctaaggag gttttgtact ttgtatactg tctcgtgaga gtcaaacttt aggattagat
     6121 agttttaagt tatctttgct aaaatgagtt agtctcctta aaaataatca aaaaagtttt
     6181 ttaaaaacgc ttgcaattat gcttgaaaag gagtatactt ataagtaacg caaacgtttg
     6241 cgtctgaaaa atacgcaacg ttccattatt ttaacacacg aggtgctatt atgaaaaaac
     6301 gtcaaagtgg tgtgttgatg cacatctctt ctcttccagg agcttacgga atcggatcat
     6361 ttggtcaaag tgcttacgac ttcgttgatt tcttggtccg tacaaaacaa cgttactggc
     6421 aaatccttcc attaggagca actagttacg gggattctcc ttaccaatct ttctcagcct
     6481 tcgcaggaaa cactcatttt atcgatttag atatcttggt ggagcaaggt ttgttggaag
     6541 caagtgacct tgaaggagtt gactttggta gcgatgcgtc tgaagttgac tatgctaaaa
     6601 tctactatgc acgtcgtcct cttttagaaa aagcggtgaa acgtttcttt gaagtcggag
     6661 atgttaaaga ttttgagaaa tttgctcaag acaaccaatc atggcttgag ctctttgctg
     6721 agtatatggc tatcaaagag tattttgaca atcttgcttg gactgaatgg ccagatgcag
     6781 atgctcgtgc tcgtaaagct tcagcacttg aaagctatcg tgagcaattg gcagacaagt
     6841 tggtttacca ccgtgtgact caatacttct tcttccaaca atggttgaaa ttgaaagctt
     6901 acgctaacga caaccacatc gaaatcgttg gggacatgcc aatctacgta gcggaagatt
     6961 caagtgatat gtgggcaaat ccacatctct tcaaaacaga tgtcaatggt aaggctactt
     7021 gtatcgcagg atgcccacca gatgagtttt ctgtaactgg tcagctttgg ggtaatccaa
     7081 tctatgactg ggaagcaatg gacaaagacg gctacaaatg gtggattgaa cgcttgcgtg
     7141 aaagcttcaa aatctacgat atcgttcgta tcgaccactt ccgtggcttc gaatcttact
     7201 gggaaatccc tgctggttcc gatacagcag cacctggtga gtgggtgaaa ggtccaggct
     7261 acaagctttt tgcagccgtt aaggaagaac ttggtgagct aaacatcatc gcagaagacc
     7321 ttggcttcat gacagatgaa gtgatcgaat tgcgtgaacg tactggcttc ccaggaatga
     7381 agattcttca atttgccttc aacccagaag acgaaagcat tgatagccca cacttggcac
     7441 ctgctaactc agttatgtac acaggaacac acgataacaa tacggttctt ggttggtacc
     7501 gtaatgagat tgatgatgcg actcgtgagt acatggctcg ttacacgaac cgtaaagaat
     7561 acgaaacagt ggtacacgct atgcttcgta cagtattttc atcagttagc tttatggcaa
     7621 ttgcaactat gcaagattta ctagaattgg atgaggcagc tcgtatgaac ttcccatcta
     7681 cccttggtgg aaactggtct tggcgtatga ctgaagatca attgacacca gctgtcgagg
     7741 aaggtttgct tgacttgaca acaatttatc gccgaattaa tgaaaatttg gtagatttaa
     7801 agaaataaga caataatcag gagacaacta aacatgttat cactacaaga atttgtacaa
     7861 aatcgttaca ataaaaccat tgcagaatgt agcaatgaag agctttacct tgctcttctt
     7921 aactacagca agcttgcaag cagccaaaaa ccagtcaaca ctggtaagaa aaaagtttac
     7981 tacatctcag ctgagttctt gattggtaaa ctcttgtcaa acaacttgat taaccttggt
     8041 ctttacgacg atgttaaaaa agaacttgca gctgcaggta aagacttgat cgaagttgaa
     8101 gaagttgaat tggaaccatc tcttggtaat ggtggtttgg gacgtttggc tgcctgcttt
     8161 atcgactcaa ttgctactct tggtttgaat ggtgacggtg ttggtcttaa ctaccacttt
     8221 ggtcttttcc aacaagttct taaaaacaac caacaagaaa caattccaaa tgcatggttg
     8281 acagagcaaa actggttggt tcgctcaagc cgtagctaca aagtaccatt tgcagacttt
     8341 actttgacat caactcttta cgatattgat gttactggtt atgaaacagc gactaaaaac
     8401 cgcttgcgtt tgtttgactt ggattcagtt gattcttcta ttattaaaga tggtatcaac
     8461 tttgacaaga cagatatcgc tcgcaacttg actctcttcc tttacccaga tgatagtgac
     8521 cgtcaaggtg aattgctccg tatcttccaa caatacttca tggtttcaaa cggtgcgcaa
     8581 ttgatcatcg acgaagcaat cgaaaaagga agcaacttgc atgaccttgc tgactacgca
     8641 gttgtccaaa tcaacgatac tcacccatca atggtgattc ctgaattgat tcgtcttttg
     8701 actgcacgtg gtatcgatct tgacgaagca atttcaattg ttcgtagcat gactgcctac
     8761 actaaccaca caatccttgc tgaagcgctt gaaaaatggc ctcttgaatt cttgcaagaa
     8821 gtggttcctc acttggtacc aatcatcgaa gaattggacc gtcgtgtgaa ggcagagtac
     8881 aaagatccag ctgttcaaat catcgatgag agcggacgtg ttcacatggc tcacatggat
     8941 atccactacg gatacagtgt taacggggtt gcagcactcc atactgaaat cttgaaaaat
     9001 tctgagttga aagccttcta cgacctttac ccagaaaagt tcaacaacaa aacaaacggt
     9061 atcactttcc gtcgttggct tatgcatgct aacccaagat tgtctcacta cttggatgag
     9121 attcttggag atggttggca ccatgaagca gatgagcttg aaaaactttt gtcttatgaa
     9181 gacaaagcag ctgtcaaaga aaaattggaa agcatcaagg ctcacaacaa acgtaaattg
     9241 gctcgtcact tgaaagaaca ccaaggtgtg gaaatcaatt caaattctat ctttgatatc
     9301 caaatcaaac gtcttcacga gtacaaacgc caacaaatga acgctttgta cgtaatccac
     9361 aaataccttg acatcaaagc tggtaacatc cctgctcgcc caattacaat cttctttggt
     9421 ggtaaagcag ctccagccta cacaatcgct caagatatca ttcacttgat cctttgcatg
     9481 tcagaagtta ttgctaacga tccagcagta gctccacact tgcaagtagt tatggttgaa
     9541 aactacaacg ttactgcagc aagcttcctt atcccagcat gtgatatctc agaacaaatc
     9601 tcacttgctt ctaaagaagc ttcaggtact ggtaacatga aattcatgtt gaacggagct
     9661 ttgacacttg gtactatgga cggtgctaac gtggaaatcg ctgagttggt tggagaagaa
     9721 aacatctaca tcttcggtga agattcagaa actgttatcg acctttacgc aaaagcagct
     9781 tacaaatcaa gcgaattcta cgctcgtgaa gctatcaaac cattggttga cttcatcgtt
     9841 agtgatgcag ttcttgcagc tggaaacaaa gagcgcttgg aacgtcttta caatgaattg
     9901 atcaacaaag actggttcat gactcttctt gacttggaag actacatcaa agtcaaagag
     9961 caaatgcttg ctgactacga agaccgtgac gcatggttgg ataaagtcat cgttaacatt
    10021 tctaaagcag gattcttctc atctgaccgt acaatcgctc agtataatga agacatctgg
    10081 cacttgaact aatactcttc gaaaatctct tcaaaccacg tcagctttat ctgcaacctc
    10141 aaagcggtgc tttgagcaac ctgcggctag cttcctagtt tgctctttga ttttcattga
    10201 gtataagatg caaatttata ctaatacatt ttgtaaaaaa gcgagtttcg attgaaattc
    10261 gcttttttaa atgctgtgga tttgggtcaa tcttgtctaa aaatagggaa atcctagata
    10321 cagtgaaggc tttaaatgct ggtttttact gtcttcagcc ttatattttt tcgtagttgg
    10381 ttacctcata tctcttgtat tcgcttacat aaagtattat aatataattg taggaaagaa
    10441 ggtgttttta tgatatacac acttaaattg gtgttgttta ttacctttct tgtaataagc
    10501 ttgttacctg ataagatttt tggaaaaaat aaaaaaattt ggaaaatagt ttttgcaata
    10561 ttgacggcag tggcagcatt tatatttatg tactaagtta ttttaagaat gtagggaaat
    10621 aaaccctaca ttctttttag ttttttctgt tttctaaatt ctatttatcc aagcgcttca
    10681 acatttcttg cttcttcgct tcaagttctg cacgcttttc ttcgatttcg gcatgttttt
    10741 tctcgagttc agaacaactt gcaccattgc taaattcttt tcgccatcag gagatagggt
    10801 gagtcgacat gtctattact cacccaaagc agtcctacaa agcaggaatt ttctgttact
    10861 tttttggaaa tagtaacgtt tatacagctt tgacacttcg tatcaaagcg ccaaacacac
    10921 tccgagggat ttacagaaag cagaaaagga atgatctggt ataagatcat tccttttctc
    10981 tctttttctt taagtaatta tatacaatgt acgacgaagt cgtcattgca atgctgatcc
    11041 accacctaaa gggaacttta aacaacattg ataagataaa gaatataaac aacgaaaata
    11101 cgttataccc aattaatttt attgtatatc tcatgattaa aagttaatcc ttccgttgtt
    11161 aggaatggca tcatttttat cccataattg tgttaaataa gtccccggtg ataataaatt
    11221 catagcggat tctaaagcaa catcatttac aaaccaacta cctagatatc tagaaattgc
    11281 tgaacgaata gcactttttg ctgcatgttt tccttttact ttaattagat ttgcaaggcc
    11341 tgcagtagtt cctcctaatg ctaaagctat tgcagtatct aatagagcac ccatttgatt
    11401 aactgtaata ccttgccaag ctgctctaaa tggagagtat gtaggtggga ttgtataatc
    11461 gccttgtaat tgtcggttaa ttacttcttt gatccattgt tgtgagacgt ctggatgaaa
    11521 agattggatt tcgtttgcaa gtgtattgat ttgttcttct gttagagaag tgacaggttg
    11581 aagttccata tttgtttcaa tttgtgatac ttgttcagaa gcgtatacag ctgaaacact
    11641 tggaatcgct gatacaatta acacaattga cgtcaaaaaa accgaaataa atttcattaa
    11701 tttgttcatg agcttttctc ctttttattt gtatttgctt acattttatt atatactgtt
    11761 attatagtca agaaaaatat gctattatgt taaaaaaata tttttcaaaa tataaatgga
    11821 cggatttatt ttggattctt tttgtaattg gggcatgcct cttgacgggt aatagtagtc
    11881 ttttccccct tacccatcaa gaattctctt ttcgtggtag cgtttggggt ctggtactgg
    11941 ccttatatca cttattgttc attgataagt ttgtaatttc gaatcgaaaa taaaaattag
    12001 aactatgatt gactggctac ttttaatatt gattttggag gaagattttg tctctattat
    12061 ttattatttt aaatttatct attttgtaca agatttattc tttgagacgg gagaagtcga
    12121 aatacttgat ttatacggcc tatatcatat ttggggtaaa tgtagtatat ggtattcaat
    12181 ggttattaaa agaactgatt tcaactattt ccacttaata tgtatgaaaa ctataacaaa
    12241 acgcataaga ttaaggtttt taagcacctg ttcttatacg tttttgtaat attgaagatt
    12301 ttcggtaagt tttctacttt tgcgaagtct agtttagaat gctttcccaa ccaaaatctc
    12361 tgcttcgatg gtaatctctg tcagttggct ccagtcaatc ttgctctggt caacgtgaaa
    12421 gaggagagga gtcatactga gtagggcttg gagttgttct gctgtgatag tcttagtcag
    12481 agaggcagtt tgactagata ggatggtaaa gtgttcctgg aaatgctcct tgatatcttg
    12541 gttagaatac tccttgtttg tcagctggtc ctgtactctt tgacggattt ctttgaggtg
    12601 attttcagtt gggataacct ttatcaagat accgtctttg gataaaacgc gacgaaattc
    12661 tccatagttg gcaggtgaga agatatcaag cagaatatcc atgttagcgt cttttatagg
    12721 aagtcgtgcc aagtcgccaa cgaaccaatt gactgcccag ttgggttcac ttttagcagc
    12781 gatttggact gaatctttgg agatgtcaaa ggcatagaaa gttttttcag agtgactttc
    12841 ttgtagtttg cgagaataga atccttcacc acaaccgata tccaaaattg ttgtggtagt
    12901 ttttgagctt gcaagcaagt cagatacagc atctaagata gcttggtaaa agccggcttc
    12961 taggatttgt tgacggtttt gaaaattttc cttgtcatag ttagcagatt gcttgatttg
    13021 aggtgctaga ttgacatagc caaatttcgc caagtcaaaa gaatgacggt tgcagcactt
    13081 gaaattagtc tctaacagag tcagattttc ttgacagata ggacaggcaa aggcagtcgc
    13141 agaagcaaaa cgctgaaatt tgggcttgag atttgtattc atagtttaag tgtatcaaaa
    13201 gaggcaaatg aaagcaactt taggaataag tagatgggag attcagtaga aataaaacta
    13261 attctccaat ttatagaatg aaattgcttt tatatctaaa ttgctatata ataatgataa
    13321 ggaggaaata agtatgttaa aagaagtatt aaccgttgca aaagttgcga aaaaatcttc
    13381 attatttttg ggtggtgtcg catttggtac ccttggtttg aaaatcttag caagtaagga
    13441 agctaaaaaa ggttattcta aagctttggc taaggcttac aagttgaaag acgagctaga
    13501 tgcatctgtt tctgttgtga agcaacatgg agacgatgtc ttgcaagatg ccaaatattt
    13561 gtacgagcaa gagaaaaaag aagagcaatt agatagcctt ataggtgaat aatatgtctt
    13621 ttaaagtgct acatagagga taccaacata tccgactatc atcttctttt tcacttacct
    13681 tggatattca agactatctt cgttccttgg cgagagatga aaaggggatt gagtctatcc
    13741 agttttacat ggatcaacag cactttactc tacgcataaa agaaggcttt tctgtattag
    13801 ataatgcaga agccttttta aaaagaattg ataaagggaa agtttctgag ttgatgactc
    13861 ttcccattcg tagagaagag agtgcttatt ctattgtttc aggtgcagcg gttaagcgtg
    13921 tactttttcg tagttttgtg ccgtatccta ttcgctatat atggacttgt tatcaggctt
    13981 tgggttatat tagagaagcc tatcaaacac tagcgcgtaa ggaactaacg atggaagtct
    14041 tggactgttc ggctatttta ttgtccttgt ttatgaacca atccaagaca gctagcaata
    14101 tcatgtttat gcttgatttg gggaatcatt tagatcagtg gtccttgaaa aaaactgcaa
    14161 cagatttaga acagagtctt cttgcaaaag agagcgatgt attcctagta cagggcgata
    14221 cggttgttag tataaagagt tccgatgttc aaataggaga tgtcttgatc ttatctcaag
    14281 gaaatgaaat tctgtttgat gggcaagtag tttcaggttt aggtatggtc aacgaaagtt
    14341 ccttgacagg agagagtttt ccagttgaaa aaagagagtc tgatttggtt tgtgcaaata
    14401 cagtattaga aactggagag ttacgcattc gtgtaacaga taatcagatg aacagccgta
    14461 ttttacagct gattgagttg atgaagaaat ctgaagaaaa caagaaaacg aaacaacgct
    14521 atttcatcaa gatggcggat aaagtcgtca aatataattt cttgggggct gggctgactt
    14581 acctattgac aggttctttt tctaaggcta tttctttcct attggtcgat ttctcctgcg
    14641 ctttgaaaat ctctactcct gtagcttatt tgacagttat caaggagggg ttgaaccgtg
    14701 aaatggtgat taaggatgga gatgttctgg agaaatatct ggaagttgat actttcttgt
    14761 ttgataagac aggaacaatc acaactagtt atcctatagt tgaaaaggtg ttaccttttg
    14821 gagactatag tgaggaagat attctcagaa tcagtgcctg tcttgaggaa cacatttatc
    14881 atcctattgc taatgccatc gtcaagcaag ctgagataga gggaattgaa catgaggaaa
    14941 tgcatgggaa actccaatat atcgcaagca aggggatcaa atctcatata gatggccaac
    15001 cagttcttat tgggaattat gtcttgatgc aggatgagca gattcatatc agttcagaac
    15061 aaaatgcttt aattgaagag tacaagagtc actacaatct cttattcttg gcttatcaaa
    15121 atgaattgat tggaatgttc tgcattcata ctcctttgag aaaagaagca aaaacagcct
    15181 tggataaact taaggcacag gggaaaaaat tgattctggc aacaggagac accttgatta
    15241 ggacagagga attagtcaaa gatttgccct ttgatcaggt ctatacagac ttgaaacctg
    15301 atgggaaatt tgagttagta gagaaactgc agaaagcagg tcacactatt ttgatggttg
    15361 gagatggctt gaatgactca gcggctttaa ctctatcaga tatcggtgtg gtgatgaatg
    15421 agagtgcaga tatttctaag cagatgagtg atatcttatt gttagataat cgtttggatt
    15481 tcttccaaga gttggattcg ttatcatcat ctttgcaaac actcatcaag aaaaatattc
    15541 aggataccgt tgtcgtaaat agtagtttga ttggctttgg cttatttaat tggttcagtc
    15601 cttcaaatct ctctatctta cataatctaa caaccttgcg cattgtcctg cgtagcctgt
    15661 ctattaaaaa tagatagatg agagttatta acagcaaaaa ggagttacct ttctcgaggt
    15721 taactccttt gtttatagat aaatgttgaa tagtttagta agtcaataca aagtattttt
    15781 tcttcccacg acggataaca gtcagttcat tttctaactt atcagcgtca ctcaagacat
    15841 agtcaaggtc ttggatgcgg tcgccgttta cgtagatggc tccgttttgg acgtcttcac
    15901 gggcttggcg ttttgagtta actataccag atgagacgag cagttccacg atattgttgt
    15961 tttcgtctgc ctgtacttgg tagtttggca caccacgaag tccttgtttg agctctttga
    16021 cagaaaggtt tttgatgttt cctgcaaaga gttgctcagt gatgttaagt gcttctttgt
    16081 aggcttcttc tccgtgaaca agtgtaacaa cttcacgagc caagactttt tgagccaagc
    16141 gttcgtgtgg cgctgcttca aattgtttac gaatatcttc aatctcatca agtgacaaga
    16201 aagtaaagat tttcaagaag cgaacagcgt cagcgtccat cacgttcatc cagaattggt
    16261 acatttcgta tggagaagtc ttttcgggat tgagccagac ggcatttcct tctgatttac
    16321 caaatttctt accagttgca tctgtgatta gtggaacagt gataacgtga ccagtcttgt
    16381 ccgccttacg acgaagcaat tcggtaccag ctgtcatatt tccccactgg tcagaaccac
    16441 cgatttgaag agtgacatta tggtcttggt taaggacgaa gaagtcgtac ccttgcatga
    16501 tttggtaagc gaactcagtg taagaaattc ctgtttcgat ccgtttttta acagattcct
    16561 tactcatcat gtagttgacc gtgaagtatt ttccaatatc acggaggaag tcaatgaagc
    16621 tgatgctgcc aaaccagtcg tagttgttga ccatgacagc cttgttttcg ccattttcaa
    16681 agtcaagaaa acgagaaagt tgtccttgga tagacttgac ccagccatct actgtgtctt
    16741 ttgtttggag actacgttca gcatctttga aggacggatc tccgatgaga cctgtagcac
    16801 cgccaacgag cgcataaggt ttgtgacctg ctagttgcaa gcgacgactt gtcaagattg
    16861 cgacaaggtg gcctaggtga aggctgtcag cagttggatc gtagccagta tagtaagaaa
    16921 cttgaccttc ttctagggct ttacgcaaag cttcttcatc agtcgtttga aatatcaaac
    16981 cacgctcttt tagctcatca aaaatgtgca tgtgtctttt ctccttttta aaattattgt
    17041 ttctacctat tgtatcacaa acttgggcaa tagcctagca gaatagggaa gaaagtggct
    17101 attttattga aaatttccct tttgtggtat aatagataaa gtgaggaaat ccatgcaaaa
    17161 tcaattaaat gaattaaaac gaaaaatgct ggaatttttc cagcaaaaac aaaaaaataa
    17221 aaaatcagct agacctggca agaaaggttc aagtaccaaa aaatctaaaa ccttagataa
    17281 gtcagccatt ttcccagcta ttttactgag tataaaagcc ttatttaact tactctttgt
    17341 actctgtttt ctaggaggaa tgttgggagt tgggattgct ttggggtacg gagtggcctt
    17401 atttgacaag gttcgggtgc ctcagacaga agaattggtg aatcaggtca aggacatctc
    17461 ttctatttca gagattacct attcggacgg gacggtgatt gcttccatag agagtgattt
    17521 gttgcgcact tctatctcat ctgagcaaat ttcggaaaat ctgaagaagg ctatcattgc
    17581 gacagaagat gaacacttta aagaacataa gggtgtagta cccaaggcgg tgattcgtgc
    17641 gaccttgggg aaatttgtag gtttgggttc ctctagtggg ggttcaacct tgacccagca
    17701 actaattaaa cagcaggtgg ttggggatgc gccgaccttg gctcgtaagg cggcagagat
    17761 tgtggatgct cttgccttgg aacgcgccat gaataaagat gagattttaa cgacctatct
    17821 caatgtggct ccctttggcc gaaataataa gggacagaat attgcagggg ctcggcaagc
    17881 agctgaggga attttcggtg tagatgccag tcagttgact gttcctcaag cagcattttt
    17941 agcaggactt ccacagagtc ccattactta ctctccttat gaaaatactg gggagttgaa
    18001 gagtgatgaa gacctagaaa ttggcttaag acgggctaag gcagttcttt acagtatgta
    18061 tcgtacaggt gcattaagca aagacgagta ttctcagtac aaggattatg accttaaaca
    18121 ggacttttta ccatcgggca cggttacagg aatttcacga gactatttat actttacaac
    18181 tttggcagaa gctcaagaac gtatgtatga ctatctagct cagagagaca atgtctccgc
    18241 taaggagttg aaaaatgagg caactcagaa gttttatcga gatttggcag ccaaggaaat
    18301 tgaaaatggt ggttataaga ttactactac catagatcag aaaattcatt ctgccatgca
    18361 aagtgcggtt gctgattatg gctatctttt agacgatgga acaggtcgtg tagaagtagg
    18421 gaatgtcttg atggacaacc aaacaggtgc tattctaggc tttgtaggtg gtcgtaatta
    18481 tcaagaaaat caaaataatc atgcctttga taccaaacgt tcgccagctt ctactaccaa
    18541 gcccttgctg gcctacggta ttgctattga ccagggcttg atgggaagtg aaacgattct
    18601 atctaactat ccaacaaact ttgctaatgg caatccgatt atgtatgcta atagcaaggg
    18661 aacaggaatg atgaccttgg gagaagctct gaactattca tggaatatcc ctgcttactg
    18721 gacctatcgt atgctccgtg aaaagggtgt tgatgtcaag ggttatatgg aaaagatggg
    18781 ttacgagatt cctgagtacg gtattgagag cttgccaatg ggtggtggta ttgaagtcac
    18841 agttgcccag cataccaatg gctatcagac cttagctaat aatggagttt atcatcagaa
    18901 gcatgtgatt tcaaagattg aagcagcaga tggtagagtg gtgtatgagt atcaggataa
    18961 accggttcaa gtctattcaa aagctactgc gacgattatg cagggattgc tacgagaagt
    19021 tctatcttct cgtgtgacaa caaccttcaa gtctaacctg acttctttaa atcctactct
    19081 ggctactgca gattggattg ggaagactgg tacaaccaac caagacgaaa atatgtggct
    19141 catgctttcg acacctagat taaccctagg tggctggatt gggcatgatg ataatcattc
    19201 attgtcacgt agagcaggtt attctaataa ctctaattac atggctcatc tggtaaatgc
    19261 gattcagcaa gcttccccaa gcatttgggg gaacgagcgc tttgctttag atcctagtgt
    19321 agtgaaatcg gaagtcttga aatcaacagg tcaaaaacca gggaaggttt ctgttgaagg
    19381 aaaagaagta gaggtcacag gttcgactgt taccagctat tgggctaata agtcaggagc
    19441 gccagcgaca agttatcgct ttgctattgg cggaagtgat gcggattatc agaatgcttg
    19501 gtctagtatt gtggggagtc taccaactcc atccagctcc agcagttcaa gtagtagttc
    19561 tagcgatagc agtaactcaa gtactacacg accttcttct tcaagggcga gacgataatt
    19621 ctctaaatga agtggccaat caatggattg ccactttttt cttttcgtgt tacaataagg
    19681 gtatgaatca gtatcagaaa aagattgtta acggaaaaat ttattcgctc ctatccggct
    19741 taatatgggg aatctgtgga attttaggag agtacttctt tactcattat caggtgtctt
    19801 cgggctggat tacctctatg cgtttgacac tggcagggag tcttgtactc atttggtctg
    19861 caatacaatt aaaatcgcaa gtgctagata tttggcgaga caagaaaaat tacctgccct
    19921 ttttagccta tgctattttg gggatttttt cagttcagta ttttttctat ctctgtgtag
    19981 aatactcaaa tgctacgaca gcaactattt tacagtttat tagccctgtc tttatcctct
    20041 tttacaatcg cttggtttat caaaaacgag cgtcaaaaag cgctgttttc tatgttttgg
    20101 ttgccatgct gggtgtttgc ttgatggcga caaagggaga cctctctcag ttatccatga
    20161 cgccgctagc tcttataaca ggtttgctga gtgccatggg tgttatgttt aatgttatct
    20221 tgccccaacc ttttgctaag cgttatggtt ttgttcctac ggttgggtgg gggatgattt
    20281 tggcaggttt gtttagcaat gtcctctcgc cggtttatca gctttccttt actcttgata
    20341 tttggagtat cttgatttgc ctcattatcg ctttctttgg aacggctttt gcttttttca
    20401 tttccatgaa ggctgtgtcc ttggtttctc ctttggtggt tgccgttatc agtgccagtg
    20461 aacctctctc ttctgctctc ttgagtgttt tgttcttagg attagtagtg gattggtccc
    20521 tccttctagc tatagccttg attattttac ccatgatatt tttgtctata gaagaagcga
    20581 aagaaagtag ataaaaagtc ttttcttaat tctaaaagtg tgctatactg gaatagtcaa
    20641 taaaacacgg ggagatagtt gtgaagagtg tttttaggtt gtatcggtag gggcttgctt
    20701 ttaccgacag cacgttttat ctcacatccc taaaaaatca tacctaaaaa cagacaaaaa
    20761 ggtttcaaat ttgaggcctt ttttggtaga ataggtatca ttataacgaa ccaggaggca
    20821 cctatgactg ctacaaaaat gaacgctcaa gaaattatcc aatttatcgc caatgctgaa
    20881 aagaaaacca gtgtcaaagt aacctttgag gggcaactcg caactgctgt gcctagctct
    20941 gttgtcaaac taggaaatgt cctattcgga gactggaagg acgtggctcc gcttcttgaa
    21001 ggtttggtag aaaatcaaga ttatgttgtc gagcaagatg ctcgtaattc tgcagttcct
    21061 ttgctagata agcgtgctat caacgctcgt atcgagccag gtgctattat ccgtgaccag
    21121 gtggaaattg gtgacaatgc tgttatcatg atgggagctg ttatcaatat cggtgctgaa
    21181 atcggtgctg gaaccatgat tgacatgggt gccatccttg gtggccgtgc cattgttgga
    21241 aaaaatagcc acgttggtgc aggtgcagtt ttggcaggtg tgattgagcc agctagtgct
    21301 gaaccagtcc gtgtcggaga caatgttctc atcggggcta atgcagtggt tatcgaagga
    21361 gtccaaatcg gtagtggttc agttgtcgca gcaggagcta ttgttaccca agatgtccca
    21421 gaaaacgtgg tagtagcagg tgttccagct cgtattatca aagaaattga tgcccaaact
    21481 caacaaaaaa cagcgctaga ggatgcgctt cgtaccttgt aattgtaaaa gtaaaaaaga
    21541 ggcggaaccc tttttccagc ctctttctgc tatatcggag gacagataga tgttagattt
    21601 gattcagact agacgagatt tacaccagat tccagagatt ggcttggagg agttcaagac
    21661 tcaggcttat ttgctggatg tgattgagaa attgactacg ggcaaggatt ttgttcaaat
    21721 tcgtacttgg cggacaggga ttttggtcta cctgcaggga agtcagccgg agcgaaccat
    21781 tggttggcgg acagatattg atggcctgcc tatcgtcgaa caaacaggtc taccttttgc
    21841 ttctcaacac caaggtcgca tgcatgcctg tggtcatgat tttcatatga ccattgcctt
    21901 aggctgtctt gagcgcgccc ttgaggagca acccaagaat aatctgctct ttctatttca
    21961 gcctgctgaa gaaaatgaag ctggtggtat gctcatgtat gaggacgatg cttttggaga
    22021 ttggttgcca gatcaattct atggtctcca tgttcgtcca gatttgaaag tcggccagat
    22081 tgcgactaat actcatacac tctttgcagg aacttgcgag gtgaagatcc gtttcaaagg
    22141 caaaggtggc cacgcagctt ttcctcatga agccaatgac gccttggtgg cggctagtta
    22201 ctttgtgacc caagtgcagt cagttgttag ccgcaatgtc aacccaatcg agggagcagt
    22261 ggtgaccttc ggcgtttttc aagctggaac caccaacaat gtcatcacag acacagcttt
    22321 tttacatgga actattcgtg ccttgacaca ggacatgagt ctcttggtgc aaaagagggt
    22381 aaaaacagtt gcagaagggg ttgcagctgc ctttgatatg gaagtcgaag tggaactcaa
    22441 acaaggtgga tacctacctg ttgagaacaa tccagccttg gcgcgtgaac tgatggactt
    22501 ctttgacgag aaagacggaa tcgagttgat tgatatcgaa cctgctatga caggcgagga
    22561 ctttggttat ctcctttcaa aggttgatgg cgtgatgttt tggctaggta tcgatagtcc
    22621 ctacgctctt catcaccctc aaatgagtcc taaggaagaa gtcttagcta ttggggtggc
    22681 tgcggtgtct agtttcctga aaaagaaggc agcagaatag agggcttgtc tatgaaatcg
    22741 gaattacgca agcaagtctt gcatgaaatg aaggctatat ctcaagagca aaaacaggct
    22801 atagaccaag ctttaaccga gcggctttta caccatccct tctaccaaga agccaaggtc
    22861 atcgcaacct acctctcttt ttctcatgag tttcaaacgc gggaactgat tgagcaggcg
    22921 ctgaaggacg gcaagaaggt tttaataccc aaaacttatc ccaaggggcg catggagttt
    22981 gtggcctatg atccgcaaca gttggtaaaa acttcctttg ccttactgga gccacaggga
    23041 gatgtggaag tggtggatgc atctcagatt gatttgattc atgttcctgg tctggctttt
    23101 acgacgaaag gatatcggat aggatacggt ggaggctatt atgaccgcta tctggaacat
    23161 ttttctggtc gtactttgag tacgatatat ccttgtcaaa ttcaggactt tatacctgaa
    23221 aaccatgata ttcctgttca ggaggtatta attgatgaag gaaatctttg atagacgtta
    23281 ccctgtgacg agtttcttcc tcttagtgac ggccttggta tttttactaa tgttggtcac
    23341 tgcaggcgga aactttgaca gggcagatac attatttcga tttggagcca tgtatgggcc
    23401 agctattcgc ctctttcccg agcaggtttg gcgtctcttg tctgccattt ttgttcatat
    23461 tgggtgggaa catttcattg ttaatatgct ttcactttat tatcttggaa ggcaggtaga
    23521 ggagattttc ggttctaagc agtttttctt tctctatctt ttatcaggaa tgatgggcaa
    23581 tctctttgtt tttgtattta gtcctaaatc cttagcagca ggcgcctcta cctctcttta
    23641 tgggctattt gccgcgatta ttgttcttcg ctatgcaact cgcaatcctt atatccaaca
    23701 gctagggcaa tcctatctga cactttttgt ggttaacatt attggaagtg ttctgattcc
    23761 aggaatcagc ctagcaggcc atatcggtgg tgcagttggt ggcgcatttc tagcagttat
    23821 ctttccagtt agaggagaaa aacggatgta taacaccagc cagagattag gagcggtagt
    23881 cttgttcgta ggactcgcca ttttgctttt ctacaaggga atgggaatgt gacgaagttg
    23941 aaagaaaatt tgtgtaatga aaaaagataa ggcatttttt gaaccttatc tttttatttt
    24001 attccttctc agtcaattct tttccaagtt ggatgaggta attcttcaaa tcatctttga
    24061 cttgtggatg tttgagggcg tagtcaatag atgttttcat aaagccaaac ttatccccaa
    24121 cgtcgtaacg agctcctgta aattcacggg caaaaacacg ctgtgtttta ttaagagtat
    24181 cgattgcatc agtaagttgg atttcatttc cagcaccagg agcttggttt tcgaggattt
    24241 ggaaaatttc aggcgtgagg aggtagcgtc cgataatagc aaggtcgcta ggagcgtcct
    24301 ctggagctgg tttttcaaca aaggtttcaa cactgtaaag accatctttt ccttcgcctt
    24361 gcggagcaat aaccccgtaa gcagatactt cgtcatgagg gactggcatg acagcgatag
    24421 tagacgcgtg ggtacgcttg tagtcatcca tgagttgttt ggtaagtgga acagcctttt
    24481 cgtctgtgat atccatcaag tcatcaccaa gcataacgac aaaaggttca tttccgacga
    24541 aagccttggc ttgcaaaaca gcatctccga gaccgcgtgg atgagtttgg cggataaaat
    24601 gcagacgcat gccagttgtt tcatcaacta gcttcaaaag atctgttttc cctttttctt
    24661 tgaggttata ttccaattcg aagtttgaat cgaagtggtc ctcaatagaa cgttttgatt
    24721 taccagtgac aactagaata tcttcaatac ctgatttgag agcctcttcc acgataaact
    24781 ggatagttgg tttgtctacg attggcaaca tttctttggc aagggccttg gttgctggta
    24841 aaaatcgagt tcctagtcca gcagcaggga taactgcctt tctaactttt gatgtcataa
    24901 aaatcctttc tatagagggt taagaccact cattttctgc tttaaattca ttgttcatga
    24961 tgtcataaat ggcatctttg atattggttc cgtgataaat aacttggtaa atagcctgtg
    25021 taatgggcat atagactcca agttcttggg ctagttcata ggctgctcga gtcgttgaaa
    25081 ttccttcgat taccatgccc atattagctt ctatatcagc tagggattct cctcgtccga
    25141 gagcatctcc agctctccag ttacgagagt ggatggaagt tcccgttacg atcaaatctc
    25201 ccacaccaga taagccgcta taggtcaatg gactggcccc gagtgctacc cctaggcggg
    25261 tgatttctgc taaacctcga gcgatgatgg ctgccttagc attatcacca aatccaagac
    25321 catgtaaagc tccagcaccg acagcaataa tatttttaag agcaccagca gtttcaaccc
    25381 cgataacatc cgtattggta taaagtcgga agtagtgatt actaaatagc tcctgaacgt
    25441 attgagctgt ttgtaaatct ttagaagcag cagttattaa agttaggtca cgcacaatgg
    25501 tctcttctgc atgactaggc cctgaaacaa cgacgatatc actacggaga tgttcaggaa
    25561 tttcttcttc aagaatggtt gataatcgtt tatggctatc aggttctaat ccctttgatg
    25621 cgtgcatgat gataacctta tggtccaagg tttgtgcaac ttgctgggca acaagtcgtg
    25681 tcacttttgt tgggacaaca aacaaaatcg catccacatt tttcaatgtt tctgctaagt
    25741 cggtgtaggc aatgatattt tcgtctagaa cgacatcttt aaagtagtgc ttattagtat
    25801 ggtgtgtatt aatttcattg atttgctcgg gaagatttcc ccaaatacgt acctcgtgtc
    25861 cattgtcatt taagacttgt gaaagggcgg ttccccaaga accaggcccc aagacggcga
    25921 cggtttgttt ttccatgatt tcctccttga tagatttctt tctcttattc tatcatattc
    25981 taggggattt tgcacttgca ttactggggt atggtggaaa aatacacaaa gaccgagatg
    26041 aagggataaa ctcttagtct ttagttaaag tgagaagaaa tctgatagat agtttgattc
    26101 agtatatgct tataatagag gtaaacaact caggaagttc ttgtaggttg cgagagtttg
    26161 gcgaaaaaat taaaagatta cgtttggcta aaaaaatcag tcgttcagaa ttttgtggtg
    26221 atgagtctga attaagtatc cgtcaattaa ttagaattga aaatggagaa tccagaccaa
    26281 cactaacaaa gttaaaatat attgctgaac gtttggaggt tgaagattac aagttgatgc
    26341 caagttatat agagttggat aaggaatacc tagaattgaa gtatttcttg atgaggactc
    26401 ctacatacga agatgaaact atcgcccaaa agaaagagag tgtttttgat aagatttttg
    26461 aagagtatta tgataggcta cctgaggaag aaagatttat catcccaaat tattcatatc
    26521 tagcactagc gaactacaca gttcaaaaat taccagaaaa gctagttgaa atactgtcct
    26581 tctggtgatt ttgcttaatt tctgatgttc gagacatgat tgaggagatt tgtcttgatt
    26641 ttttcctaaa aaagggcaga ctcctccctt ggtttgatgc tcgattttta aaataaggtg
    26701 acttattctg ttaggcagtt ttcccctgcc ctctagctct atatggaaca gggagtatca
    26761 gatttatctg gcagattgta tcaaataagg cttgaaactg ttttgaatag gcgtatagac
    26821 ttgagaattt gagaatatgt cgtctagcag tagagacata ttttccggca atatgaagga
    26881 agagacgtcg aaaacgcttg atagtcaagg cctttacttc atcaccagct agctgcttta
    26941 aaaagaggta gagattataa gccagacagc ccatcatcat acgtacttca ttcttaatca
    27001 tggtcgaact atctgtctta tccccaaaga atcctgcttt cctttctttg ataaagtttt
    27061 cagcattccc tcgttcacga tagaattgaa acagctcctc actatctaca ctgcttaaat
    27121 tggtcaaatg aactttttta caaccataaa aaagagcact taatcgtact cttctctttt
    27181 aaggattagt tgaattaatt caaatccact agttctcctg tttctaggta gactaggcgt
    27241 tcacaaatgt tagcaatgta atcagcgaag cgttccagat gccctatgat ataaaggtat
    27301 tgagttccat tgggaattga ggtttcttgg tctttcataa gtccaatgat ttcctttgat
    27361 aaggcataat aatattggtc aatctgttca tctttttgag caatactaat agcttttgag
    27421 gcttggtgca aaggaaaggc aaccaataaa tcggctagca tgctgaggga taatttaccc
    27481 atttggtgta actgttcttc gtcaggggct agttgatttt cttttagttg caaaacagct
    27541 ttggcaatgc ctgccatatg gtctcccata cgttcaaggt ctgaacaaga agacatgatg
    27601 ctaatcacaa atcgaaggtc agacacttgt ggctgctgca aggccaacaa acgggcacag
    27661 gtcaattcga tagcgctttg accttggttg atagcatgat ccttattgat aattagctct
    27721 gccatctcct tgtctttgga ggctaaggcc agtaaggctt ttgaagctgt ttcaaggaca
    27781 agttgcccta gtcctaaaaa ggattgttct aattcatgca attctaagtc aaattgattt
    27841 ctcataggtt tttccttcct tatccgaacc gtcctgaaat atagtcttct gtgcgctgat
    27901 cttttggatt ggtaaacacg tcaacggtat ctccaaattc gcaaatttct cctgttaaga
    27961 aaaaagcagt tttatctgaa atacgtgaag cttgttgcat gttatgggta acaatgataa
    28021 tcgtataatc cttttttagt tgctgaatga ggtcttcaat ttttaaagtg gagatagggt
    28081 ctaaggctga agtcggctca tccattaaca gaatatcagg ttctactgct aaagctcgcg
    28141 caatgcaaag gcgttgctgc tgaccgccag ataaggacat agcactcttt ttaagatcat
    28201 ctttgacttc ttcccaaatg gctgcccctt ttaaagattt ctccactaag gcatctaatt
    28261 gttttttgtc tcgaatacca tgtgtccttg ggccataagc cacgttatca tagatagaca
    28321 tggcaaaggg attaggctgt tgaaaaacca tccctacacg cttacgtagc tgattaaggt
    28381 tgaatttgct actataaata tcttgctcat ctaagaggac ttggccttca atatggcaag
    28441 aaggaaccaa atcgttcatc cggttaaggg tttttagaaa agttgatttg ccacaaccag
    28501 atgggcctat caaggcagta atctgtcttt ctggtaattg aatcgaaata ttttttaagg
    28561 cttgaaaatc cccgtaaaat aagtctaggt gtctgactga aaatgttccc atactaggaa
    28621 gctcctttca caagttttcg agataataag cttgatagag tatttatcat taaaacagta
    28681 ataatcaaaa tcacaccggt agcataggct tcattgacat gtagcccctc acttgacagc
    28741 atatacatat gcagggctag agaacgacct gaagacatga gactacttgg cgtattggta
    28801 gaggtaccta atgtatacat gagggcagct gtctcaccaa cgatacggcc aatagctagt
    28861 atcactccag ctaaaatacc tggcatggca actggtagaa caattctaaa aacagtccgt
    28921 aacttacctg ccccaagtcc ataacttgct tgacgcatga tatcactaac agataaaagg
    28981 gcttcttctg ttgagcgaat aatgactggc aacaccatga tgactgaggt taagattcct
    29041 gataacagag agtattgaaa acctaagaag actacaaaga agagcatgcc aaacagacca
    29101 aaaacaatgg aaggaatccc agacaaggta tctgaggcca atcgcatgat tttaacacaa
    29161 agggaatctt tttttgtata ttccacaaga taaaaaccag caaaaatccc tatgggcaag
    29221 gctaaaagaa gagcaccaaa gaccagaata acggtggaaa taatcgctgg cataagggaa
    29281 atgttctcag aagtataagt ccaagaaaag agggatagac ttagatgagg taagcctttg
    29341 atgaggataa aaccaatgat taaaaagaga gagccaaagg ttaaagctga aaaacaataa
    29401 acgagaagtt ttagcaggta tttactcata agatgatttt cctttcaagt aggcaaagta
    29461 ggcattaatc aagagaataa ggaaaaagag aactgctgag gttgcaataa gggcttccct
    29521 atgctgacct gatgcgtaag ccatttccag aacaatattg gttgttaagg ttctggttcc
    29581 tgaaaagagt ccacttggaa taatcggctg gttgcctgcc accaaaataa ctgccatggt
    29641 ttcacctact gcgcgaccga ttcctaaaat aactgctgat aaaataccag atctcgcagc
    29701 tggcaagatg acactaaaaa tactccgttc atgactagct cctagagcca agctaccaga
    29761 ataatacgtt ttgggaactg ttcggatagc agattctgac aaactgataa tggttggcaa
    29821 aatcattatt cctaatagta acgaagcggt taggacactc atgccatttc ctaaaaagct
    29881 tctaatccaa ggcaccaata attgtaggcc gaaaaaacca taaacaatag atggaatggc
    29941 cgccatcaag ttgatagctg attttaagaa gccatagacg ggctttggac aataataaac
    30001 cataaacacc gatgtcaaga tgcctgttgg caccccaatc acaatcgctc ctaaggtaat
    30061 taataaggaa ccaacgatca ttggtaaaat accatagctt gccggaatgt tcgttggcga
    30121 ccaatcactg cctaataaaa aacgggcaaa gccgtagtta gccatgaaag gtaagccatt
    30181 actaaaaata aagaaacaga ttagcaaaat agctacaaca gctactgttg cactcatgaa
    30241 aaaaattgcc ctaaaaactg cttctttgaa ggcttgtttt atcacatctt gtcctttcta
    30301 gtgaagaaag taagggagat acgacacctc cctacttgcc ttctttatct tattgtacga
    30361 tgaaacgtct gcatctcttt agagatttat ggagcaaaca ttttatttaa tcttgtccca
    30421 ggtggttaat ttgccactaa aaacgtctgc aagttcagcc atactgactt ggcttgcctt
    30481 attgtcatta ttgaccacaa cagcaatacc gtctaaagca atagcatcat gggtgagact
    30541 cttaccttct tcaggagtta attccctaga aaccatacca atatcagcgg ttttctcctt
    30601 aacagcggta atacctgctg aagacccatt agaggtaata tcaatcgtaa cttctggatt
    30661 ttctttttta taagcttctg ctaatttttc cattattaaa gaagatactg aagtggaacc
    30721 tacaacagac aacttgcctg ataagtgttg gcttgtatat tctgtggttt cagttttagc
    30781 ttcaataaat ttattatctg tgaccacttg ttgaccttgt ttggagtgga taaagctgat
    30841 aaaatcttga cctagcttgg aaagattaga agaccaaaca atgttgaagg gacgttgaag
    30901 agggtattca ccatctaaaa ctgtgtctcg actagccttg acaccatcaa tctctaaagc
    30961 cttgacagat ttcgttaaag atcccaagga gatgtagccg atagcattag cattcccttg
    31021 aactgctgag agaacacctt ctgtactatt ttgaatcaca gctgttttgg cagtgttgtc
    31081 aattttttta tcaccgtctt ttttgagaat ccctgtgatt tctgtgaagg caccccgtgt
    31141 tccagagcca ttttctcgtg aaatcacctc aatcgttcct gaagctgact gtttggaagc
    31201 agctgactga ttgccacagg caacaagccc aaatcctgat aagccaatgg ctgcaagagt
    31261 aagcattttt ttgaatttca taataatcac ctttatctct atgtattttt cttgtgtagg
    31321 cttactacat ttatagtcta acaagtcttt gtaaaggttt atccctgatt catgtaaaga
    31381 ttgtgtaaag aatcaaaaaa agccactttt gaaaaatggc tgctcctaaa aatagcttta
    31441 aaaattatta gtcctgtgcg aaagattggt taggaagaaa aatcgtgaag caactgcctc
    31501 tgccaagctg acttgtcacc gtgacttggc cacctaataa ttgactgagt tctttgacaa
    31561 tggcaaggcc aagaccagtg ccaccagttt gtctgcttcg acctttatta actcggtaaa
    31621 aacgttcaaa aatacgatcc tgctctaatt gactaatacc aatccctgta tctgatacag
    31681 aaatcttaat gccttcgttc accttttggg tcttgacctc aatttttccc ccttgttcag
    31741 tgtaacggat ggcattggat aaaagattga gtaagatttg ggaaagtaat tgactatctg
    31801 atacgagggt gacatcatct ggcacctgca cctttagctg taaatccttc ttcttgagct
    31861 gaggttgcaa gctttgagtc aaatcctgta caaattctgc caaagaaagg gtcgtccatt
    31921 gtataggcat ttgttgagcc ttagataagg taagaagatg ctcaacaata tgctcaagac
    31981 gcaagctttc tttgtaaata atgtctagaa agtcatcctt gagcgcttct tcttcagcag
    32041 acatcccctt aatggtttca gcaaagccct taatcgaagt aactggtgtc ctcaattcat
    32101 gggaggcatt tgagacaaag gctaaattta acttttcata agttctaatc gttgttaaat
    32161 catatagcaa gacgagcaca gcttccacag attgggtggg gctaaaaacg ggaactgctg
    32221 tcacttctaa aatcaagtca ccctcatgaa acccacttac ttcttgtttt aaccttgttt
    32281 tttgatcaaa ggcttggtga actaaatttc gaatatccat ccgtttgagg tcatcaagtg
    32341 aacttatgtc gccgtccaca tcgggaaaat aatgaggcag agagcgactg gataataaca
    32401 tctgaccttg agcggaaact aaaaacgtcc ccatggttag gtgcgacaga agaacctcca
    32461 ttgtttcggc taggtccttg tattgctgat cctgttggga gactttggtt tttaggccag
    32521 acacatactg agccaaagac tttaagtctt cttgcccttt ttctaaaaag tattcactac
    32581 tggtcaagag aggttggtgc aaggtctcaa aagcaacttc ccatttccaa aggcaaaaga
    32641 gccagtagcc accttgtccc aaagaaaggg ctagaagaaa gagaccgatg cctttactga
    32701 tccaagttaa tgccatccct gcaatcagaa tgaggctaac acttagattg actagccaaa
    32761 attgaaggta gcgtttcatc tataactcct tgaacttata accataaccc cgaatggttc
    32821 gaataaattg aggggcttta ggattgtctt caattttttc cctcaactta ccaatatgaa
    32881 cgtccaccaa acgtgtttcc tgcccaaagt cataccccca gatacgttcc aaaagacgct
    32941 ctctagtcag tgtcatgttg ggatgtttca taagatagag caagagttca aattcttttg
    33001 gggtcaaact cagtaactta ttcgccttgt agacttcatg acgctcaggg tatactttca
    33061 aggtcccaaa tagccaagaa tcgtcagcga tattatctga atcatctcct tcttgttctc
    33121 ctttagttcg cctgaggaca gccttgacac gcgccagcaa ttctctaggg ctaaaaggct
    33181 tggtcaggta gtcatcagcc cctaattcca aggccaaaac cttatcaaat tcatcacttt
    33241 tcgcagaaac catcataatt ggagttttga cgcctttggc tctcagccgc ttacaaactt
    33301 ccatgccatc taattgtggt aacatgatat caagcaagat aaaatcaaag ggttctgttt
    33361 ctgccaaagc taaggccttc cgtccatttg ttaccaattg agtagaaaag ccttccttac
    33421 ttaaatggta gtcaagcaat ttcagaatgt gttcttcatc atccactaat aagacttgtt
    33481 ttgtcatcta ttatctccta ttggtaacat tataacacaa ttatcagaaa tcctaacatt
    33541 gctaaatcag attaaatttg cctatcaaga ctagtatctg gtcaaacgct caatcatctc
    33601 cttgtgctct ggataggtcg ccagtagatc taccctttca aataattcaa aatcctcaaa
    33661 ttcaaaacca ggagcaacaa gacaagaaac cagagcatca tccttatcaa ctgttgatcc
    33721 ccaaatagtg cccttaggaa cacagtagtg aagttgttgc cctttggata tgtccaggcc
    33781 taaagtgact gcttcgtagt gaccatctgc tgtaatcatg tgaacagtaa gtggggatcc
    33841 tgcatgaaaa taccagattt catctgctgt caatcggtga aaatgtgaag gattcgtttc
    33901 ttctaataag aaataaatac tggtataaag cgcccttccc ttaccagcaa ggtttatagt
    33961 gtctgaagct ttttttgttt gtctaaaata gccaccttca acatggggag ctaactctag
    34021 agttcttatc aagtcttctt tatccgtcgg agccaatggg ttgaagtaac tcttgttcaa
    34081 agtggtttta cgatttcaag aactcctctc agttctgagg acacggtaat gattgatgcg
    34141 acggaagtaa aaatcaatcg ccctaaaaaa agaattagcg aatgattctg gtaaaaagaa
    34201 atttcacgct atgaaggctc aagcgattgt cacaagtcaa gggagaattg tttctattgc
    34261 catgatatga agttgttcaa aatgagttgc agaaatatcg gaaaagctgg taa
//
LOCUS       DAVHLA010000020        33330 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVHLA010000020 DAVHLA010000000
VERSION     DAVHLA010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33330)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33330)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33330
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.020"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(40..924)
                     /locus_tag="VVO77_001092"
     CDS             complement(40..924)
                     /locus_tag="VVO77_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEU5693112.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(1069..2220)
                     /locus_tag="VVO77_001093"
     CDS             complement(1069..2220)
                     /locus_tag="VVO77_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HEU5693113.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            complement(2366..4132)
                     /locus_tag="VVO77_001094"
     CDS             complement(2366..4132)
                     /locus_tag="VVO77_001094"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HEU5693114.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEASDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRS
                     IYDPEEFERALKWVKENVKEGFDHNREDLVLSREEKDRQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYCACQLLGPLHK"
     gene            complement(4215..7331)
                     /locus_tag="VVO77_001095"
     CDS             complement(4215..7331)
                     /locus_tag="VVO77_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEU5693115.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVILPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVSFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKEDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNDYEVFTQHIDSLESNNLSIDLKGLKGKKVRISLRSAGIPLSLA
                     EVEVYTYK"
     gene            complement(7341..9635)
                     /locus_tag="VVO77_001096"
     CDS             complement(7341..9635)
                     /locus_tag="VVO77_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEU5693116.1"
                     /translation="MKLWYKKAASNWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKDCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPKTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQEREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            complement(9694..10494)
                     /locus_tag="VVO77_001097"
     CDS             complement(9694..10494)
                     /locus_tag="VVO77_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU5693117.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            complement(10491..11264)
                     /locus_tag="VVO77_001098"
     CDS             complement(10491..11264)
                     /locus_tag="VVO77_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU5693118.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            complement(11289..11759)
                     /locus_tag="VVO77_001099"
     CDS             complement(11289..11759)
                     /locus_tag="VVO77_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU5693119.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            complement(11750..12181)
                     /locus_tag="VVO77_001100"
     CDS             complement(11750..12181)
                     /locus_tag="VVO77_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU5693120.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVDELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVQNAQNSLFNVKQQLNVEEEEDLCL"
     gene            complement(12174..12614)
                     /locus_tag="VVO77_001101"
     CDS             complement(12174..12614)
                     /locus_tag="VVO77_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HEU5693121.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            complement(12626..13264)
                     /locus_tag="VVO77_001102"
     CDS             complement(12626..13264)
                     /locus_tag="VVO77_001102"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HEU5693122.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMDLMAEKFKTYGQRK"
     gene            complement(13379..14782)
                     /locus_tag="VVO77_001103"
     CDS             complement(13379..14782)
                     /locus_tag="VVO77_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEU5693123.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGSTEGTAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            14958..15731
                     /locus_tag="VVO77_001104"
     CDS             14958..15731
                     /locus_tag="VVO77_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU5693124.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCVYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
     gene            complement(16859..18364)
                     /gene="adcA"
                     /locus_tag="VVO77_001105"
     CDS             complement(16859..18364)
                     /gene="adcA"
                     /locus_tag="VVO77_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEU5693125.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVTKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYVEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISIMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNIAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(18374..19180)
                     /locus_tag="VVO77_001106"
     CDS             complement(18374..19180)
                     /locus_tag="VVO77_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEU5693126.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            complement(19173..19877)
                     /locus_tag="VVO77_001107"
     CDS             complement(19173..19877)
                     /locus_tag="VVO77_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEU5693127.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYSVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVSHA"
     gene            complement(19877..20317)
                     /gene="adcR"
                     /locus_tag="VVO77_001108"
     CDS             complement(19877..20317)
                     /gene="adcR"
                     /locus_tag="VVO77_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEU5693128.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            complement(20472..21740)
                     /gene="dltD"
                     /locus_tag="VVO77_001109"
     CDS             complement(20472..21740)
                     /gene="dltD"
                     /locus_tag="VVO77_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEU5693129.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKGELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            complement(21733..21972)
                     /gene="dltC"
                     /locus_tag="VVO77_001110"
     CDS             complement(21733..21972)
                     /gene="dltC"
                     /locus_tag="VVO77_001110"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEU5693130.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            complement(21986..23230)
                     /gene="dltB"
                     /locus_tag="VVO77_001111"
     CDS             complement(21986..23230)
                     /gene="dltB"
                     /locus_tag="VVO77_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEU5693131.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            complement(23227..24777)
                     /gene="dltA"
                     /locus_tag="VVO77_001112"
     CDS             complement(23227..24777)
                     /gene="dltA"
                     /locus_tag="VVO77_001112"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEU5693132.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKSDSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     ITDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDSVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            complement(24798..24929)
                     /locus_tag="VVO77_001113"
     CDS             complement(24798..24929)
                     /locus_tag="VVO77_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEU5693133.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            complement(25160..25864)
                     /locus_tag="VVO77_001114"
     CDS             complement(25160..25864)
                     /locus_tag="VVO77_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEU5693134.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGDLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPISNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            complement(25934..27760)
                     /gene="glpO"
                     /locus_tag="VVO77_001115"
     CDS             complement(25934..27760)
                     /gene="glpO"
                     /locus_tag="VVO77_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEU5693135.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKSDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTSAANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            complement(27802..29310)
                     /gene="glpK"
                     /locus_tag="VVO77_001116"
     CDS             complement(27802..29310)
                     /gene="glpK"
                     /locus_tag="VVO77_001116"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEU5693136.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            complement(29469..30896)
                     /locus_tag="VVO77_001117"
     CDS             complement(29469..30896)
                     /locus_tag="VVO77_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU5693137.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSENENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPTFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLVAIRQLLFT"
     gene            31061..31933
                     /gene="hslO"
                     /locus_tag="VVO77_001118"
     CDS             31061..31933
                     /gene="hslO"
                     /locus_tag="VVO77_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEU5693138.1"
                     /translation="MNKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            31920..32900
                     /gene="dusB"
                     /locus_tag="VVO77_001119"
     CDS             31920..32900
                     /gene="dusB"
                     /locus_tag="VVO77_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEU5693139.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(33130..>33330)
                     /locus_tag="VVO77_001120"
     CDS             complement(33130..>33330)
                     /locus_tag="VVO77_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein A"
                     /protein_id="HEU5693140.1"
                     /translation="NANGSMATGWLKDGDTWYYLEASGAMKESQWFKVSDKWYYVNGS
                     GALAVNTTVGGYRVNANGKWVN"
BASE COUNT         9996 a         7366 c         5782 g        10186 t
ORIGIN      
        1 tgacgtggtt tgaagagatt ttcgaagagt attagtctat tatttcttct cagcgcgaag
       61 ggctgacaag atttgtgttc ggatatcatc cacaccattt ggagtatttg gtaaaaagat
      121 ggtttgattt cctttagagg caaaggtatt caaggtatcc aaatactggt tggtcaagag
      181 gatagacatg atttgttctt ctgtcatgcc aacattggct tccttgagtt cggtgataga
      241 ctctgccaat ccatccacaa tcgccttacg ttgttgggca atccccacac catgaaggcg
      301 gtctttttct gcttctgctt cagctgcagt gacaatttta atcttgtcag cttccgccaa
      361 ttcttgtgct gcgacccgct tacgttgcgc cgcattgatt tcattcatgg attgcttaac
      421 ttctgcatct ggttcgacct tggtaatcaa ggttttcacg ataatgtagc cgtaagtggt
      481 catttcttct gctacttggt gttgaacctc aagggcaatc tcatcttttt tctcaaacaa
      541 ttcatccaag gttaattttg gaacagaaga gcgaagagca tcttcgatat aagatttaat
      601 ctgagattct ggacgtatga gtttatagta agcatctgtc acgctctgct cgttgacacg
      661 gtactgagtc gctacattca tcataacgaa cacattgtcc ttggtcttag tctcaaccac
      721 aatatcactt tgcaacaagc gcaactgaat ccgtgctgca atcgagtcaa tcccaaaagg
      781 caagcgaata tgaataccgc tattagcaac cttttggtat ttcccaaagc gttcaataat
      841 cgccaccgac tgctgacgaa ccacataaac tgtactcagt gtgactatca ccaataggag
      901 cacacaaaca atcagaaaaa tcatgaaaaa tattgccata atggaacctc cacaagtatt
      961 tttctagtat tatagcacat ttaaagaagg ctgtgccgtt tttactgcga tttttcctga
     1021 aatgtcaata attagaggtg aattgtccta ttgtcgtcca atctcttgct aaaataactc
     1081 tttataaaag gcaatcgttt cttctaaggt tggcataaat ggatttcctg gtgcgcaggc
     1141 atcaatcaag gcattcttag aaaggtattc aaagtcgaaa tctttttctt caataccaag
     1201 ttcagtcagt ttcttaggaa tacctactgt ctcagaaagc ttctcaatct cagcaatcgc
     1261 ataatcggca cattcttgat ctgatttacc ttctacatga agtcccaagg ctttggcaac
     1321 attgcggaaa gcttctggta cacgtttagc attttcacgt tctataactg gtagcaacat
     1381 ggcacagcac acgccatgtg gcaaattata tactgcaccg agttggtgag ccattgagtg
     1441 aacataacca agaccagcat tattaaagct cataccacca aggaagatgg cattgaccat
     1501 accttcacgc gcttcaatat catgtccatt ttctacagca cgaggaagat attccttgat
     1561 aagctcaata gcaccaatag acagtttctt ggttacatca taagcaccag gtgttaccaa
     1621 agcttcaaca gcgtgagtca gagcatccat accagtagca gcagtcaggc ctttaggttt
     1681 ggaaagcatg agttccgggt cattaacaga gataagagca aggctattct tgtcaaccat
     1741 taccatctta accttgcgtt cttcatcagt aatcacatag ttaatagtga tttctgcaga
     1801 agttcctgcc gttgtattga tagccacaac tggcaagcct tttttagcag acttatgaag
     1861 cccttcataa tcctgtggtt ttccaccatt tgtagccatg atagaaatac aactagctgc
     1921 atcctgtgga gaacccccgc caagactgat gataaagtca cagccatgtt cttgcaaagc
     1981 agctacccca tctgtgacat ttttacaagt agggtttggc tctacatcgc taaagatgac
     2041 atattcgatt ccttctgtat ccagtggttt taaagtctta ggtaaaatat cactgccttc
     2101 gatgtactta tctgtaacca aaagtgcctt tttatagcca agttccttga tataaggacc
     2161 cacttcattt acaacacctt ttccaataag gttgactgcc ggaacataaa atgtagccat
     2221 ataattttcc tcctgcgcct ccgcgctatc tatttaacat cattatatta ctttttgtat
     2281 tcgtttttaa ttatttgtga attgtttaac aaatcttttt aaaaggatag gagggacgta
     2341 agttcacctc ctatataaac aagttttatt tatgtagtgg tcccaacaac tgacatgcac
     2401 aatagtctgc tgattctaga tcttctgttc caaataagga ccaattttta ggtctaaaga
     2461 tatcttcctc aggtacatta tgcatattga caggaattct caacatagaa gccaaggtaa
     2521 tcaagtctgc tccaatgtgt ccatatgtta tggctccgtg attagctccc caattattca
     2581 tgacgtcata gacagacttg aaagcacctt ttcctgtcaa acgtggagca aaccaagtag
     2641 ttggccatcc tggatctgta cgattatcta aagtatggtg aacatcttca ggaagttcaa
     2701 gtgtataacc ttctgcaatt tgtagcactg gaccaacccc ttttagaaga ttgagacgta
     2761 ccattgttac tggcatatcc cccttcgtca agaaacgagt tgagaatcct cctccacgga
     2821 agtattcgcg gtttgctggt gggaagtctg tattttcaag catagcctgc acttcacttt
     2881 cttccaactc ccagaatggt ttcataacag gtttgccatc tcgagtagct tgacctgtac
     2941 catccaatgt acaagaacca gagttgatta gatgtaagaa gccagctgca gcacgaccct
     3001 ctaaagtatg tcccgttaca cgtttaacag cctctgggct ccaataagta cgcacatcag
     3061 caaagatttg tggagtattt gttaatagat aattaaagag catagacaca ccatttagtg
     3121 aatcattctc tgtcgcaaat acaaatggtt ttcgaatacc attccagtca aactgagtat
     3181 tgaggaaagt ttccataaaa tctccatttg gaaaatggtc tgtccactga cgttgacctt
     3241 ggaaaccagc tactaaagca tggtgaccaa ctgcttcttc ctcaaaacca agttcagcaa
     3301 gtcttgggtt accaaccatt aagtcacgtc caatcatgaa catcttaata acaaattccc
     3361 attgtctatc tttttcttca cggcttaaaa caaggtcttc acggttatgg tcgaatcctt
     3421 cttttacgtt ttctttcacc catttgagcg cacgttcgaa ctcttcaggg tcgtaaatac
     3481 tacggtccat acggcgcgtg aactccgtca tatctaccga ttcatttcgc attcctaggt
     3541 attcttggaa gaaatccgga tttacaatag aaccaccaat ccccatcgaa acactaccca
     3601 ttgataggta agcagtgtct ctcatcaagc cagttgcaag agctgcacgc gcatagcgta
     3661 aaagtttttc tttgacatct tctggaatat ctgtgtcact agcttcctga acatctcttc
     3721 cataaatccc aaaggctgga atcccttttt gagcatgtga agctagtaca gctgcaagat
     3781 agacagctcc tgggcgttct gtcccattaa atccccaaat agcatgagga atatctggag
     3841 acatatccat agtttcacta ccataacacc agcatggtgt aactgtaatt gttgcgcaaa
     3901 catttgattt tttaaacaac tcatgggaag ctgcagcctc tggtacacgg ccaatagtag
     3961 atggagaaat cacgcattcc acaggttccc catctggata tttcaatgtg cttgaaatca
     4021 aatctgccac acttttagcc atgttcattg tttgcacttc aagtgattcg cgtacacctt
     4081 gacgacgacc atcaatagtc ggacgaatcc caatacgtgg atgttgaatc atactatttt
     4141 cctcttattt ttctgtttct ttcatactac catctccatt atatttacgg tagcctgggt
     4201 gataattttt aaaattactt ataagtataa acctctacct ctgctaaact taaaggaatt
     4261 cctgcgcttc tcaaagaaat tctaaccttt tttcccttca gtccttttaa gtctatggat
     4321 agattattgc tttctaaact gtcaatatgt tgtgtaaaaa cttcataatc atttgaatca
     4381 tatataataa tatcaaaatt tgataatctc tgaatttcag catctgttct attataaata
     4441 attaactttt ctaattcttc ggtttgtgct aaatctatct cccaccatga aggagaatct
     4501 tctttggtat gagtcactga atgatgacca taatctccgt ttttatttcc atcaactgct
     4561 agacgagaaa aaccattgta atccgttgaa ctctgtcgag tttcttttgt taatgcaata
     4621 ttagaaagtt tcttcggagt tctctttgaa ccatagactt caacttccgc taaacttaac
     4681 ggaatagctg ctgattttaa ttctattttg actagcttag cccctacaga aggtactttt
     4741 aaagataaca aaccatcaac tactttatca aaatgtcttc taaaaacttc ttctcctgat
     4801 gaagatagaa aaataacatc aaaattagat aaacgctgag gttcggcatc tgttctatta
     4861 taaatatcaa ctttagaaac cgtaaactct tctcccagat cgacctgcca ccaagcgtta
     4921 gaatctgcct tagtatgagt caccgaatga tgtccgtaat ctccatcttt attaccatca
     4981 actgctaaag cagctacacc ctcataattg gttgaacttt gagtagctac cttatttgta
     5041 gagactactt tatcttctgt tattttatct atatcctctt cagattgctt accatctgat
     5101 tctctaaaaa cctctacttc tgctaaactc aaaggcactc cactcgttag taatttaact
     5161 ttaatatacc ttgctccttt ttctttgaaa tctagactaa cagattcacc cgacaaatta
     5221 ttaacatgtt tcttagcaac ttcgtttcta ttattgtcat atagaatcac atcaaaatta
     5281 gatagacgtt gagtctcagc atctgtgcga ttataaattt taacaagccc aactttatcc
     5341 atttttttca aatcgacttc ccaccaagag ggattatctg ccctagtgtg tgttaccgaa
     5401 ccagagttaa aattaccatt tctgttacca tccacagctc tattagggtc tccattgtaa
     5461 tctacagaac tttgtgttgt tggttttgca tatgctatat tcaaattacc atcattaaat
     5521 ttatctggtg ttgggaaaga gactggacct gtcccctcag tatttataga catctctacc
     5581 attccattat gattaaccgt aatggtataa acatgggtat tctcatccca attttctgta
     5641 taagtataat gatttttatc gccacttata tttatctgag gtttatgacc agtatgccct
     5701 tttaatgtaa gtgttgttgt cctaaagtca ttatctacag gattgatgga ataatttttg
     5761 cttatccagt tcgctaactc taattcttct ttcttccaac tttttgatgc atcaaaattt
     5821 cctgataatg cccacatagc tgtcttatct gtcctgtaat tattcaataa aatatgtaaa
     5881 ttatttggat tttctttaac aacagcgtaa gtatgtggcg tcaaatctaa cgataacgac
     5941 tttgtattat tagtatacat aggcaatatt acttgctgat ttttattgat attagcatta
     6001 ctattataaa tataccagga attacctaca cgctgagcat acccatctcc ttcataaagt
     6061 tttggataaa gcgagtttaa atagttgact ttactagaca attcctcact atttttagtc
     6121 aaaatttttg cattagggaa tatagatgaa atcttttcct tatcaatttt ctcatgtatt
     6181 acaggaagaa tatgatatct cccattatta tataaaggca ttgtttcatc attcgaataa
     6241 agtccttgat aaaatccgtt taatgaacta atcctacctt ctccattcca aaatacagct
     6301 tttgttctat ttacaacttc ttccttactt ggagctggat tttgtatagc atgtctaaag
     6361 aaaggaataa tacctttagt aaatgctgga gttggtacat catttgtcat aaatgtatac
     6421 gcggcacatt cgaaattata aactgtgcct cccccagtat atacattcat catttccata
     6481 gcaatcattg attctggttc cgatgcatag gatctcatat ccctagctct tccagtttca
     6541 aatgtgtttg tataatgttt ttcccaccat ttccatgtat ctgttgatga gccccagtta
     6601 tcacataagc cactcaacca aaatccacta acgatagaat ctgtacccgc atcatctctt
     6661 attggcgtat ttttagttgc caacaccaaa tttttatgat atttttgact cgcttcaaag
     6721 aatgtcggat cattcataat agtttcccag aaccattttt catgatcatg ccagataaaa
     6781 tgcgctccat atttggcaca aacttccaaa tatttagcac tatgcggagc taactggtta
     6841 ttgtaaatcc aataattctc aatatttaaa acacctttta acacactata cttttggaat
     6901 tgttcatcta accactctgg aggaactgta ttacgctctc cagccgacat aataaccaag
     6961 aaaactggaa tgtttagact ttgagcttcc tccaacatct tgacatacca ttctctcaat
     7021 tctttcgtat ctcgtggaat acaacttgtt ggtttacaga cttttgcagg atgaagttca
     7081 atcgctgcat atggctttac atcttcagga atagcttccc atgctccctt caatgtgttc
     7141 ccccaccata atccgttacc attatcattg ccatacaacg gagaaagcaa caatggcgat
     7201 tcattattaa tcgtcgttct catttgaaca cgattatcag ccttaactcc tgctaacaat
     7261 ccaaaacata acatcccaat acatacaaac aatattgtga ttaattttct ttttattttt
     7321 tctttattca tgacttatac ctaaaaattt aactcaataa ttttttctga attaaatacc
     7381 aattcaatat tttgtacatc agtatttttg ccatatattc ttactcttac tttttgatct
     7441 ttgtttcctc cttccaattt taggaatgtt atatccccat ttttccaagc aaacgatacc
     7501 ttatatcctc ctcttactct gaaacctttc acttctcctt ctgaccaagc agaaggtaaa
     7561 gctggaatta gtgataacca attatgatgg ctctgtacta ataattcaca aattccactc
     7621 accaaaccta aattaccatc aatttgaaat ggtggatggt caagaaataa attgccaaga
     7681 gtcgcattat ttaacaaacc attaatctgg ttataagcag gttcaccttg atatagtctc
     7741 gcaaaaaaat gaatcagcca tgcagcactc caacctgttt gtgtactagc atgcaaacca
     7801 cttactaacc aattattaat cgcttgctcc ctctcctgtg aagataaaaa attagcgttt
     7861 gataatctcc tattgatagt gattttagct gcttctgcta attccggagt tttatgaata
     7921 tcaatctcat tataaggata aagcccaaat agaggtgaaa tgtgtctatg cccaggctct
     7981 acttcttcat aatcttctaa ccattcttgg atttgcccat tactacctat ttttgtttta
     8041 ggtagtttct tttttaactc cttcacacga ctaataaaat ccgaattgtc tcctaattgt
     8101 tttgcaatgc caatgcatga atcacaaaaa tatcttagaa tttgattatc aattgtagat
     8161 gatagacaag catttccttc aataccattt tttaagcgat atttattttc cggtgagaca
     8221 cttggacctg tcatcaagta gccatccacc tcaaataaat aatcttcaaa gaaaagaaat
     8281 gcttctttta tcatttcaaa atgttccgta agaatacgct catcttggaa atataaatag
     8341 tgttcccaaa tatgagtaca taaccatgga atagttaata cccaaattgc agcccccatg
     8401 gcatgagatt ggggagccgt atcgccaaaa ccatccgtat tatgatgtgc tgtaaaacct
     8461 ctagctccat acattttctt agcggttagt cttcccggtt ctctcattct ttcgagcata
     8521 tcaaataatg gatattctac ttctggtaaa tcacatggac ctaccatcca ataattcatt
     8581 tgagtattaa tattaatcgt atatttagaa ccccaaattg gatttaattc atcacaccat
     8641 attccttgaa gattggcagg taaaccattc ggttgactag acgatattaa cagatatctt
     8701 ccataatgaa ataacaagtt agtcaagtag ttactatact ttttagtgtt ttcaagaagt
     8761 agattcgttg gaatgctaag acaatcttta ctatagtcta gtttaaaatc aactctatta
     8821 aattgctcct gatatttttt tacatgttca tctttttctg taaagtaatc aatactacta
     8881 aattctccct gaagagaaga aatatctata tttccccaat aatccgtcat tgatttgaga
     8941 taaagaaata cctctgtagc attccgaata actattgtct ctcccaatac acttacttca
     9001 ccatccgtaa ccttagaatg acatactact ttaaactgaa caccttttct acctccagca
     9061 gaggccgaca ttaaaattgt acttgaatcc agtttagata cttcgtcatt aaaccgttta
     9121 tttctaccca aattaatgtt taaatttaat gtgttttgaa ctgatgacac tatacggcaa
     9181 cataaaatat tcttattaaa actcgtaaaa tattctcttt ttatttgtaa attacaacta
     9241 ttaggctcaa acacaacatt agaaatagct gtatctaaat ctagctctct ttcatacaat
     9301 gaaagagcac aagactgaat atctatatgc tcaatgtaaa gttccccaag taattcatag
     9361 tggctttgat ctcttggggt agcaaacatt gttaacttta tcaattcttc ggctttctga
     9421 atttctccat ctaaaagata ttcccgaatt tttttaagat gcaatagtga gtctggatta
     9481 tttctatctg actttcctct ataccaaata gtctcatcgt ttagttgaat acattctttt
     9541 gtagctgaac cataaatcat accacctaaa tgaccgttcc caatcggcaa ggcttcattc
     9601 caatttgagg cagctttctt ataccataat ttcactcttt acctctcttc caaaatggag
     9661 gtgatatccc aaataccacc tccacacttt ctactacttc aaaattccta aaacaactag
     9721 gataactcca atagccataa cactaaagat tagtacaacc ggattctttc cttttctaat
     9781 taatttacac attaataaag tcaaagccat agggataaat cctggaatta attttgtaat
     9841 catttcttga acagaaataa caagttcccc ctgcttaaat tctaatccaa aattaatacc
     9901 aaccattgat ggaatcaaac cacccactag tactagccct aatgctgtcg ccatactcgt
     9961 aacgcgattc aatgttcctt ttgtattatt ttcttggata agactagaac ccttagtata
    10021 cccatatttc aaaccgaaat atttaacagg aatattaata atattaaaca atattaaggc
    10081 gataaagata cctaaagcac cgccgtcttt agaataagac gcaccaatac taaaacagat
    10141 aggaactagt gtcagccaga acaaactatc tcctagacca gccagtggcc ccatcaagcc
    10201 aactttaata ccagtaattg aagctgcacc ttcatttcct tcttgttctt ccatagcgga
    10261 agtaactcca agaataaatg gtgccgctgt ttgatgagta ttgaaaaact caaggtgacg
    10321 tttcattgca ggagaagctg aatctttgtc tgggtatagt tttttcaata ctggaagaat
    10381 tgtatataga aaacctaggt tctgcattct ctcatagttc catgaagaac catacataaa
    10441 acttcgtttg aaaacttttt taagttcaac tttagttact ttattattca tcatagatca
    10501 agatcctcct caacatcact acttgaagtt gtttcttgtg gtttacttcc aatcatatcg
    10561 tagaagtatg ctaccgcaat accaactagt gagatcccaa tggttgacat tcctccatac
    10621 acagaacaaa tgaatccaat caacaagaat acccacatat ttttcttgag catcatattt
    10681 aaaagcatac caaaaccaat tgaaggtagt aaagcacctg cagagttaag tccctgcata
    10741 acgattggtg gaaccttagc aaacaagtct gccacatatt cccctccaag cataatagct
    10801 aggaaaattg gtacaatttt aaataacgtg attaaaacca aacttgaata atgataaaaa
    10861 ccgatctttg aataatctcc gtttttagca tcattatcag cttttttcac aaaataaaca
    10921 tctaaagttt ttgcaagaac atccaactgt tgggtagcaa ctgcaattgg aactgctata
    10981 gcgataccag cagtttctcc ttgaccagat aaaataccaa atgcagtacc aataatcgca
    11041 cctgaaatag tatctggtgg agtgtaacct ccaatacctg ttacaccgag ccaagttaat
    11101 tcaagagctg aaccaataag aacaccttgg gtgaaatctc ctaagactaa gccaaccatt
    11161 gcacttgtaa ctaacggacg gtgaatcata aataacggtc cattatagtc aatagtggca
    11221 ataatcccaa ctaatgtcac cagtaatgct tgtgtgaata gcatatactg tacctcctta
    11281 aattattttt ataaaaattt ttccaacatt gtaactttat cattaggaac catttgaatt
    11341 tcaactctcg ttcccttatc aactattttc ttaaaataat atttgtcttc ttcacctaga
    11401 gctacacctc ccgttacctt ttcattttcc tccgttttac tcatctgtcc tacattgagg
    11461 tactccaatt ttaaatttcc ttcaatagaa tcatacacat cttttggatt tgtatatatc
    11521 agcattgttc tcttttttat tggcacagag tttaaaactt ccacaaaccg ttttacacta
    11581 aagaaaacaa tttttaaacc taccggtgca gaaatcttta aaatagattg tcgtgtttta
    11641 tcttctgaga tgcgatcatt aacaatgata acttgctcaa tatcatactt ttttagccac
    11701 gtagtgacaa cttgaccatg taccagacgg tcatcaatac gaacaaactc tatagacata
    11761 aatcctcttc ctcctctacg ttaagttgtt gtttaacatt aaacaaacta ttttgagcat
    11821 tttgaacaat ttcttctaaa ttgatttttg aatcataact tgatattaat tccactagga
    11881 gagggatatt aaaccctgtt acaatatcaa ctgaatccaa atttaaaaac cgtgacaaag
    11941 ccacattatt aggacttcct ccaatcaagt cagtcaaaac gataacctct tgatttgagt
    12001 ctaacagttc atccacttga tttttaaaat aatgttcaaa ctctacaata ttctctccag
    12061 gcatcaaacc taatgtccta actctatcat ttgttgtctc accaacaaac atttctgcgg
    12121 tcatgagagc tccgctagca aaattaccat gactggcaac taaaattcct ctattaaaca
    12181 ttttctcttt caacaactac tcctttctta aggataatat tagcataaag tgaagtttct
    12241 cctgtagcaa caatagcata agctttctta ctacgttcat aaaagtcttc tcttctaaga
    12301 taagtaatcg ttttaagatc tgtaccatga ccttcaatca tctgtctata ggtaccccat
    12361 atcttaggaa tatcatcacc cgaaacaacg ttcataaact gaattgaact atcgacgtaa
    12421 ctatctaatg gcattaaata cagaatggaa tctaataatt ctggaatatt tacgccatca
    12481 caacgaatta gcttatttgc acatgaggca gaaggataat tcgcgtcagc taatactatt
    12541 tcatctccat gtcccatttc cattaaagtc ttcaataaat ctggagaaat atttttcggt
    12601 atatgtttta acattaatat cctccctatt ttctctgacc gtatgtttta aatttttctg
    12661 ccattaaatc catctcctca tcaggaagaa ctactggctc tccaaaattc ttagctaaac
    12721 aataaatttt tgcacaatat tcaacttctt caacaatatt aaatgcattc aataaatttt
    12781 gtgcacctgc taaaattcca tgattcgcta gtaaaactgc tctacgacct tccattgctt
    12841 tagctgcatt cacagccaat tctttcgtac catatgttgc atactcagct acccgaacat
    12901 ctttccctgc cactgcaatc atataatgac tagccggaag tggttctctg agacaagcta
    12961 atactgttgc ataagttgta tgagcatgga taattgcatc gatatcatca cgagtttgat
    13021 attgaatcaa atgcatatac cattcgctag atggcaagcg ttctccctct acaacatttc
    13081 cattaatatc catcactaca atatcggatt ctttgatttc aaagaaatca atacccgacg
    13141 gggtaattgc catcaattgt ttttcacgat cgaaaacact gagattccca cctgttcctt
    13201 tcgtcaaatc tgtttctact agcttcttgc catacttaat taattcttgt tttacatctg
    13261 acattcttgt cctcctcata tcaaaacact aaatattttt caattcacca attatccccc
    13321 cttcttgtac aaaacttaag aagggggagg gaggcaaatt tacaaactct caatcttttt
    13381 aattcttttg ggagtaataa ctctctaatt gtagaaactc ctcaataaca tggtgagctt
    13441 cttccatccc ttttaattgt cccatagcta tgagctgcac aacaatattc cccacagctg
    13501 taccctcagt cgaacctgta agaacctctt taccagttct atcagcaatc atttggttaa
    13561 agtaactggc tctagcacct cctccaatca catatatcct cttataaacc ttatgagtta
    13621 gttcttctag taactctatc gctttcctat acgtttcagc taggctttca taaacaatct
    13681 taaatagttg tccatctgtc cactctctag tttcatgatg ataagctaga tattctgtca
    13741 aagtcttgtg catatcagat tctgttgcaa attcagttga ttcagtatca atcagaggaa
    13801 gattttcttt ttctttctcc accattgtcc taatatcatc aaaagaatag gctttccctc
    13861 ttcgttcaaa tgaacgtctt agttcctcta tgatccacaa ccctgtacaa ttcttcagaa
    13921 atgtaatcac tccatcttta ccgacttcat ttgtaaatcc ataactgaag gattcggtag
    13981 taagaatcgg tgaagtaagt tccactccaa ccaaagacca agtacctgat gaaataaata
    14041 aactaccttc tgtcttaggt actgagacaa tcgcacttgc tgtatcatga ctacaaacat
    14101 tcacaacagg aatatcgcct aaaccatact ccttttttat ccttccaaga acatttccct
    14161 ctgaaacaat ttcaggaagt aaagatgaat ccaattcaaa tagttttaag atattctgat
    14221 tccaattttg actcctagga tcaaataatt gagttgttga agcaatgctt ttttctgtag
    14281 caaacttacc tgtcaagaga taattaaaca aatctggcat taaaagaatc ttattggtct
    14341 tatagaaaga gtcaggagat tcttgacgtg ccttaaagag ttgaaacaag gtatttatct
    14401 ccataatctg atttcctgtc tctgaataca gtttttctaa ttcagtcatt tcagatattt
    14461 cctttaacac tccctttgtt ctttcatcac gataatgaac aggttgtgat aacagcttac
    14521 cttcattatc aatcagtcca aaatcaactc cccatgtgtc aataccgata gataaaatct
    14581 tgtaactagt attagccaag cggatacttt caagaatttt agctagtaga aagtcaatat
    14641 cccaagataa atgccctttt actctaatag gtagattaga aaagcgattt atttcttcca
    14701 ttactagttt attttcagaa aggtaaccaa cgattgctct tccagaagtc gcacctaaat
    14761 ctattgctaa aaccgcttcc atttttcttc tctcttcgtc cttgattaag tttattataa
    14821 tccccacatt ttattttttc aatatgtgaa cgcttacttg gataatgttc aaatgttaac
    14881 ccaatattca taaaaataat tcaaattcct ccaatttgtg ctataatata gttgaaatga
    14941 taaattagga ggagcttatg ataaaagatg aacgtgtact tgaattgatt gaaattatta
    15001 aaaagaaaaa aagaattgcc gtaaaagagc tggcagaaat cactttctcc agcacaagta
    15061 ccttacgtcg tgatttaatt ttcttagaaa atcaaggtct tatcaaaaga aagcacggat
    15121 acgtgaccct gtcctctatg aacacaattg aactttctca tcaaatacgg gaaggagaaa
    15181 gtactaggca aaaaagacta atcgctagtc tcgctaaaga ctttattcgg tcaggtatgt
    15241 gtgtttatct ggattccagt acgactgtct acgaactttg tccctatctt tctgaacttg
    15301 ataatttgat tatttttaca aatggtttac atactgcaca aaccctatct gaaactgtta
    15361 aagatagctc caaaatcttt atcacatctg gcgaggtcaa acatcaatcc tgttccgtgg
    15421 tcaattacga taaggaaaat tctttattag atcattttaa tatcgattta gcattttgtt
    15481 cagcaagagg tattgatgac caatatgttt atgaagcttc tctcagccaa gctatttcaa
    15541 aaaagaatat tattgacaaa gcccatgaaa ccatcttact gattgatagc tctaaatttt
    15601 acaagactgg attttttaaa attaatcccc tatccaaata cacaaccttt atttctgaca
    15661 ccgtgccaga tcaaaaatta ttagacgcag tcgaattatt tgatggagaa tgggtttctg
    15721 atattcaatg aaaatcaaat aggaagctag tctcagcttg ctcaaagtac agatttgaaa
    15781 actgatgaag tcaagtcccc catggacacg gcaagacgaa gctgacatga tgtgaagaga
    15841 ttttcgaaga atactcgttc tgtctgctga ctgatttaca aatattcacc acatgacatt
    15901 attttcttag caaccctaaa aacagaggct ggacaaaaac tcaatttcaa gagaaatggg
    15961 gcaaatattc ccacaataaa acgcatagta tcaagttttt gcacacctga tattatgcgt
    16021 ttttctgatt ttaaagactt tgtcgcctag accctatatt tcaagaatta agtgaccttg
    16081 atgatctaaa tgtattgtgg tatactattt ttgtcatcgg ttaccgatta cgttcctatg
    16141 ggttcgtgag aggaggtgaa actaatgagc cttatcatag agctcgctct tactattata
    16201 gcggatgtta tagctggaat tatcttgtat ttcatctgca gatggctaga tagtaaggag
    16261 tagaccgaat gactagccta taaacacccg ttaaatctct aagatacgtc aaaaaagccc
    16321 ttaactacgg ccatagttag gggctttggt gttctaatga accttatcaa ttaactacat
    16381 tttagcatat aatctacaat agttcaagca ttaagtgagg ttgatgatct aaatttagtg
    16441 tggtatacta tttttgtcat cggttaccga ttacgttcct atgggttcgt gagaggaggt
    16501 gaaactaatg agccttatac cagagcttgc tcttactatt atagcagatg ttatagctgg
    16561 aattatcttg tatttcgtct gcaaatggct agatggtaag aagtagaccg actgactagc
    16621 ctataaacac ccgttaaatc actaagatac gtcaaaaaag cccttaacta tggcactagt
    16681 taggggcttt ggtgttctaa tgaaccttat acactaacta cattctagca tataagtcct
    16741 aatatttcaa gagttttatt tattttttca ggttccctta gttctgaaag gtctataatg
    16801 aagttagcca tctagtatca aaaaaccgac tagctcttat gaactagtcg atttctcatc
    16861 aatgcgccaa catttcttgg gcgatttctt ggccagatag gttatctggg tagtaggttg
    16921 gccagttgtc catttcttca aagagggctt cttggcttgt gcctccaaag aagatatgga
    16981 aatgttctgc cttaactggg gcgatattgt ggtcactaaa ctgaacatac ttgaattgtc
    17041 cagcgtcagc atctgtggct tcaaagagga aacgcacgcc acgattgcct ttcttgtaag
    17101 tcaaaatttt cttaccgaca tacttgtaag tgtatttctt gctttgtcca ccttgaacaa
    17161 attccatagt attatcagta atgttaatct tagtcacatc tgtctgatag ccttttgtat
    17221 agtaagcctt gtactcagcc tgggtcatct taccagtcaa cttagccttg tagtcaaaga
    17281 cttggtcaaa cgtgccgtct tcaaggaaag gataaactga ttgccagtta cctgcatagt
    17341 cactcaaggt gcggtccttg acagctgcat cctcgaagta accattttgg actgtcttgg
    17401 tatcctctgc cttttcaggc tcgattgctg ggccttcttg gtctgttgtt tgtttcaaag
    17461 ccttgaggtt tttctccatg atagagatgt aattttctcc agccttggtg tcctcttctg
    17521 tcagactttc taaaggattg aggacatcag ttttgacacc tgcttctttt gaaagtgtgt
    17581 tagcaagggc ttgtgaggca ttttcttcaa aatagatata ggcgatttta tttttcttga
    17641 catactctgt caattctgcc aagcgagcag ctgatggctc tgcatctgga gaaagtcctg
    17701 agattgcgac ttgtttgagt ccatagtcca aggcaagata gttaaaggct gcgtgttgag
    17761 tcacaaagct cttttgtttt gcttgagaca agccttctac gtaagcctta tccaaggctt
    17821 gcaatttttc gatataggca gctgcattct tctcaaaggt ctctttttta tcaggataat
    17881 ctgctgacaa gctgtcgcgg atgtgctcta ctagtttaat ggcacgaact ggtgataacc
    17941 aaacatgggg gtcaaactca tggtgatgac cttcttctcc atggtcatgg tccccctctt
    18001 cttcctcgcc acctggcaag agcaacatat cgcctgtcgc cttgatggtt ttcacttttt
    18061 tcttatccaa ggtatctagc aatttaggta cccatgtttc catgttttca ttttcataaa
    18121 cgaaggtatc tgcatcttgg attttggtaa ctgccttggc agatggttcg tattcatgag
    18181 gttctgtccc agcaccgatt aggagttcta cattagccgt atctcctgcg acttgcttgg
    18241 taaattcata gacagggtaa aaggttgtca cgatattgag tttaccatct gcctgttttt
    18301 gattggaaca agccactaaa aacaaggcac atagactggc tagtaataag ctaatttttt
    18361 tcacgttcgt ctcctatttg ataaaacgtc ttactaaact gattagtata aagacagtta
    18421 caaaaataat ggtaatactt gcacttgcag gtgtttctgc atagtaggaa atgtaaagtc
    18481 ctgctaccat tcccaaaaag ccaatcgcac tggcaagcag cataaccgat ttaaagtttt
    18541 tccccagacg cagggcaata ctagctggca agaccataat ggtcgatacc agaagagctc
    18601 ctgctgcagg aatcataagg gcaatagcca cccctgtcac catgttaaaa agaatggaca
    18661 tggtacgaac tggcaagcca tccacaaagg ccgtatcttc atcaaaagtt aagatataca
    18721 taggacgaag aaagagaaag gtcaaaatca aaacaaccgc cgcaatgaca aagagggaaa
    18781 tgacctgttc ttcactgata gtcacgatcg aaccaaagag atattggtcc aaactcattg
    18841 aactcgagct tttacccttg ctcatgacaa tcagagaaac agccagacct gttgacatga
    18901 ggatagctgt cccgatttcc ataaagctct tgtaaaccgt acggagatac tccagaaaga
    18961 ccgccgcaat caagacaatg gcaatagtag aaacagttgg agaaatcccc aaaaccagac
    19021 caaaggctac acctgaaagt gagacgtggc taagggtatc actcatcaaa ctctgacgac
    19081 gcaagatgag gaaggttccc aataccggtg agaaaagact catagcaata accgccaaaa
    19141 aggcgcgttg tataaagtcg taagataata aactaagcat ggctcacctc ctggccattc
    19201 tcatgaacgt tgaaacaacg ccatggcgag tcttggttac ggactagatg aatattgcga
    19261 tccgcataat ccttaacttc ttcagggtca tgggtaatca tcaaaacagc cttgccatga
    19321 tgatgggcgc tgtggtgcat gagttcgtaa aattcatttt tacttcctgc atccatcccc
    19381 gttgtcggct cgtctaggat aaacacatca gggtcagaag caaacatacg cgcaattacc
    19441 gctcgctgct tttgtccccc agatagagac cccaagcgtt tgtctcgatg ttcccacatg
    19501 ccaactgagt ccagactggc cttgatatgc tcctcatcat gagcattcaa acgacggaac
    19561 cagccttttc tcggatagcg acccgacttg acaaattcat agaccgtact tggaaaacca
    19621 gcattaaaac tggcaatttg ttgaggaaga taggctattc tcaatttctt accttgcgta
    19681 tttgtctttg aaatagccac ctttccaatg cgtggttgca gaattccaag actggccttg
    19741 atgagcgtcg tcttagccgc tccattttcc ccagtcaagg taacaaattc cccactatca
    19801 acactataat tgatatgttc aagaacaggc tccttatcat aatagaagga caaatcctct
    19861 accgtaatat atctcattat ttgatttctc ctactaaagc agtcaaaaac cgctgaatca
    19921 ctttttgttc atttggagta aactgagtcg ccacttgttc ataggttaaa agtgtatgct
    19981 catggtgatg gtggtgctcc tcagcgattg gacgagccaa gtcagtcaac tgataaaaaa
    20041 tcacacgcgc atctttagaa tctttagatg tttccaacat cccttccttg accaaagact
    20101 taatggcctt ggtaactgcc gcctgactga cattgagacg acgggccaat tctgaatttg
    20161 ttaaagattc ctctgacaag agcataagga tatgctcctg agtattggtc agggccacct
    20221 cgctagtgca atgacctatt aggatttcat gctgattttc cgcctgcaaa atcacctcat
    20281 tcaaaaaagc attgatatcc tttgctagct gtctcatatc tgactccttt ccttttagac
    20341 ttctcttttt taagagaaaa atactattct ttgacatttt gtttaccagt taattatatc
    20401 acaagcaaaa aaagagtcaa gaaaaaacgt gaaaactagt ttcattcttg aactcttcta
    20461 tattatatta tctattgaaa ttctttgaca tctccatcat aagtcgccca atctttgctg
    20521 aaaaagcgct cattcagatg gtaagtcgga gctggtgtgg gattggatag gaaaggatca
    20581 actgccttgt caaaagccaa ccaacccaac caaccaaggt gaatggtgtc cttcataaag
    20641 aaaggctccc caccgtcctt agaaaaatct gctatattgg taaaaccttg actttctaac
    20701 tggtagcgaa tcttctgcac cgtttgttgg tacatatcct ctcgtagacc agcatagtcc
    20761 atccattttt tattaacagg tggaatgata aaaatcgggt ttaccttaga tttagaaaac
    20821 tgtgttaaaa ccaactgcaa gtcattatac tctggcgact tgagataggt aaagcttttc
    20881 tgagaatcct ttaatttctt caaatccttc ttgatctgct cattatagaa ataattttcc
    20941 attcccatct cattattgga agtatttttt tcagcatctg ctttgacaac atcttctatt
    21001 gcttgataag aaaactggtc tggcaagatt tttaaatact tagctacatg cttatcgtag
    21061 ttaacatagc ctctaaccga aaactgacca aaaaaggagg cttggcgttc attaaaacga
    21121 gccaataatt caatcatttc attgtctgct gtcgacaatt ctcctttact tgccaacttc
    21181 tgaaccaggt ccttcatagc tacgtttggg aactgttgca gtaagcgagt cgctgcatat
    21241 tgactagcct gatccccaga ttgatgtttc agaaaactag tcaactggtc tccattaaaa
    21301 tactgctgga aggctgctgg atcatagcca tttttactga accactgagg tgagataaca
    21361 tacacaactt gtttattctc cagctgtggt aacatctgtt gcattccaaa atattggtta
    21421 agcgatgcag ctcccccctg tcctaaaaga taaggacggt aggaacgatt gtatttctca
    21481 gctaataccg caggatgagc accgtcaaaa cgaagccatt cactagagcc aaagaaggga
    21541 acaaaacgca catttggatc agatagtgct ctgacttttt gacttcgctc cttaaaacta
    21601 tcgatagtag tagccactgc tgaacgcttt tcagctccta gattatgatg catctcagta
    21661 ggataaaaga aaatgagcag aaaaaccaac aaaccagcga tcaagaccgg tccgaagatc
    21721 atccataagc gtttaagcat tttgtagctc cacaatacca gctatgattt tattagctgt
    21781 attccagtcg tcacgaccaa actctgttac agggacacga atgtcaaaac ggttctcaat
    21841 ctccacaatc aactcaaccg ttcccatact atccaagaca cctgcatcaa aaagatcttc
    21901 atccatcatg tcagaaacat cttccataaa caactcatca ataatttcaa taacttctga
    21961 tttgatatcc atattttatt tccttttatt ttttaaacca tagattattc aagaatccag
    22021 aaaagattaa gaatgacaac atgacaacat ggaaagtgac aaccatgcca agcaactgaa
    22081 tccagcgatt ctcaggtagg gcagccttcc ctgctttttt ccgttcctta ttgagcgttt
    22141 ttttcttgcg aacccaggca tcattgatga ccaagcctag tccatgaaag agtccatagg
    22201 cgatatagta ccaggtcaca ccatgccaaa atcccataat cagcatattt acaatgtagg
    22261 ccatgcttga ggttacatta cgatttttaa agactttctt tctggttaac accatcacca
    22321 ttcgcataaa gacaaagtca cggaaccaga aggacagact catatgccag cgattccaaa
    22381 actcctttaa atcccttgat aaaaagggct tgttaaagtt gatagggcta cggattccca
    22441 tcaagtttga gatggccaaa gcaaacatag aataacctgc aaagtcaaag aagagctcca
    22501 gaccaaaagt atacataact gccaaggcat agagattaaa gaagccacct gactgcaagg
    22561 ctaaattctt cagaggaggt agtaaggtct ctcctaaaac atgagctagg ataaacttat
    22621 acaaaaagcc ccacatgata tagcggacag attcatccag catatccatc aactcatctc
    22681 gctcaggaat agcctgataa ttttcattaa atcgcttaaa gcgatcgatt ggaccactcg
    22741 agaaagttgg catgaagaga aggaaacgga ggaattccca gagggtaaaa tccttaatca
    22801 ctccatctct cagctcgatg ataatcccaa ccgaacgaaa ggtcaggtaa gaaattccca
    22861 agaacccaag caaagactgc gttccattga tagctggttg caccttgaca aagataatcg
    22921 gaagtaggga cagaaaacta actaagtaga agacccactt gccatccttg ctttttcgat
    22981 aatgcttgta gaaaagcagg agcaatattt cccagcaaag gtaaataccc aaggcagcta
    23041 gttgattggt ctttccaccc accaacatgg tgacaataaa gaagagactt accaacactt
    23101 cataccaggc aaagcgtttc ttgaaaaaga ggcctataaa gatgggcaag gttgcagcaa
    23161 tcacataaac aaaatactga ggattgccat atggctctaa atgaggaagc tgttgaaaaa
    23221 actccatcat ctcttattca cctcgttaat caatcctttg atgtcaatct ttccatttgg
    23281 agtcagtggc aaactgtctc ggtaaaggaa tttagatggc atcatgtagg acatcatgat
    23341 gtctgtcagg tcttccttga tggccttggt aatatcgata tctcgctcaa actgctcacg
    23401 aacactgtct tttaagatga cataagccaa tagattttgt accttgtggt ccttgttata
    23461 gcgcggtact gcgacagcag attcgataaa gcgagacttg ttgaggtttt gagagacatc
    23521 ttctaactca atgcggtaac cgttgaactt aatctggaag tccatgcgtc cgccgtagag
    23581 aagcaagccc tcatctgtta tggttcccac atcgcctgtg tgataggctg gcagaccttc
    23641 aaactcaaag aaggcttctg ctgttttttc aggattgttc atataacctt ttgaaacagc
    23701 tggcccagaa acaatgattt ctccctgttc gccatttggc agtttatttc cttcctcgtc
    23761 aatgataaag gttggagaat cagccttggt atagccgatt ggtaggcgtt tgagagtcgc
    23821 taacatctcg tctgtcacgg caactgctga cagagctact gtcgcttctg ttgggccgta
    23881 agcattgatg atacgggcat ttgggaaacg ctcgcgcagt ttttgagctg ttttgaccgt
    23941 caattcttca ccatcaaagt agaaatgcgt gattccaggc attttttcac tgttgaagta
    24001 ttcagacaac atggccatat ctgcaaagga tggtgttgat gtccagatag cgattggcaa
    24061 tgaaaagata gccgcaaaga gttgcttaaa gtcctgagtg atgactgaag gaagagtgaa
    24121 aagcgtacca ccaagtgcca aggtcggtgc ccaatacatg acagacaagt caaaagaata
    24181 aggtggctgt gccagcattt gcggacgact cggtgtcgca aattccttat ccgtaatcat
    24241 ccagtttgta aagctgagga gattatcatg tgaaatctgc actcccttag gcttaccagt
    24301 cgtaccagaa gtaaagataa tgtagtaatt atcatctccc ttgactggat gcgtgatttc
    24361 atagttgttc ccttgggcaa aggcttcttg aacctgagct agatttatca ttggtgtaga
    24421 aacctgctcc aagggaaagg ctgaaatggc aataatcaag cttggctctg ctacttctaa
    24481 aatagctgaa actcgctcca aggccgaatg gctatcaatt ggaatgtagg catgacctga
    24541 cttagtcagc gctacaaagg ttgccaacat ttcatattct tggccaccaa aaacaaccac
    24601 aggagacttc tcaggcaagc ctagttggtc aatgactgca gccaaactat ccgaatcaga
    24661 ctttaaatcg ccataagtgt gttcctgccc caaaacatta tagacaggat agctaggctg
    24721 tgtctgagca aaatgctcaa tggtttcaat catatctgct attggtttat ttgacacaat
    24781 agggattctc cttcaagtta aaattcatta tagataaagc ttccttgacc ctgaccaaga
    24841 tagctaaaga agtaaagcag ccctagaaag ataagaaaat acaaggctgt ccgaccaaga
    24901 aagaggtaca attcttttct ctgtttcatc aagaaaaacc attcatttct gtaatttttc
    24961 gctaaaataa gagtgattct tactagctta tttttctacc attgtaccac tttatatagt
    25021 atcttttcaa ttgtttaccg tatgtttcca atagatttca gcttatttta aggattatgc
    25081 ggtttttcta tatctatttc aaaagaaaaa agcctgagat tttcatctca agctctagca
    25141 ataatagtta ttttctaaac taaaaaagtg agaatacaag cacggccaag gctgcaccga
    25201 taacaggtcc cacaacagga atccaagcat aagaccagtc tccgtctccc ttgtttgaaa
    25261 ttggaaggat actgtgcatg atacgaggtc caaggtcacg cgcaggattc aaggcataac
    25321 ctgttgtccc acctagcgat agaccgatac cgacaatcaa ggtacccact gcaaaggttc
    25381 cgatacctgc ctgaaaatcg taaagaccca aagcaaagat tgtcaacacc aaaacaaagg
    25441 ttccaaggat ttcgctaatc aagtttgata cagtatcctt gatggctggt ccagtactga
    25501 aggttgccag gatattgcct gcattttctt ctgcctcata gtgaggtttg aattgcaacc
    25561 aaaccaaaat ctgacccagc atagcccctg cgaactgggc taagatataa ggcaaaacgg
    25621 aagcccaagg caagtcacct tttaaagcta caccaattgt cacagctgga tttaaatgag
    25681 ctggactgag cttgccagat acaaatactg caaccgcaac tgcaatcccc caacccatag
    25741 taatcacaat ccaacctgag ctattgctct tggttttagg aagaaccaca cctgcaacaa
    25801 caccatttcc tagaagaatc aggattaaag tccctagaaa ttctccaaat aattcattca
    25861 tcatctttct gtctccatta aaaagaaggg acgagcgaca aggaatgctg ccctccacct
    25921 cttttatttt ttcttaattt tttaattctg ctaaatcgtt gttagcgaga gctgcttcga
    25981 catcagcacg gtaagttgct ttttcttctt ctgtccagtc atagaatcgt cccatttcat
    26041 ccaaaactgg ctcaacgatg ctatccaagc tatcacgcat aaagagcata tggttggtac
    26101 gacgaagaag gaagtcaact gggctaagag ccaactcgtt gcgcattgca tagtgaaggg
    26161 acaaagtatc tgccaagctg agtcctggcg cttgttccaa gctgtgagca agtgcaaaga
    26221 ctttcggtgc atttgaaccg taaagatttg ccagatagtg agcttccttg ctatccaaac
    26281 cacgtgatac tccaagttgc gcaaaggctt cgatttctga atccacattt gctgggttca
    26341 attctccacc tgaaacaggg taagttttag aattgatcaa tttaaagcta cggtcaaatt
    26401 ctgctttgag gatgtcaacc acgcgctcca tagctccttc agccatctta cggtagtctg
    26461 tgattttacc gccagcaaga gtcaaaagac cattgtcatc acggtccaag ctagacccac
    26521 gagaaactgc agatggatcc aaatatttct cagatgtgct actttcaagc ttgctgacag
    26581 cagactcaac atcttcacgt gttttttctt tggagagata agattcaaca gtcgcaatca
    26641 agttgtcaaa gctttcatca ctgatggtac cgttatttcc accattatag tcagaggcac
    26701 tgttccctgc aatcaatgga cgaagacctg cccagctgct ttcgatatca tcaatggtga
    26761 tgttggattc tggaaagcgg ttgttgacaa tgccaagtag ataatctaca tcttcttgag
    26821 ttacttttgg atgctccaaa tcacctgtgt agtctgtatc agttgtacca aagtaagtct
    26881 tgttttcacg tgggagaaca aagaccatac gaccgtcacc caaacctgtg tcgaagtaaa
    26941 ctggctgtga aaccttgatt ttgcttgaat ccactaccaa gtgaactccc ttagttgggc
    27001 gcatttgtga gaattgcgtt cccttattag acaaattacg tactttatca ctccaaggac
    27061 ctgttgtatt aataaccaga cgggccttga tttcaaatac ttggtctgtc aagagatcac
    27121 gagctacaac acctgtaatc ttgccacttt cgtcaaagag gaagccttct gccttcacgt
    27181 ggttggcaat gagggcaccg tcttggttgg cacgtttgat gttttcaatc acgagacgcg
    27241 catcgttgtt acggaagtca agatacactc cacctcctac caagccttcc ttcttcaagt
    27301 ttggctggcg ttccaagact tgatccttgc tcaaaacctt gttcgcagct gacgtgttgc
    27361 tcacacctgc taaaaggtcg tacaagtcca tggctacttt aagacggaag aggctaaagg
    27421 ttgctccatc ttcatcgtaa actggtaaga gcattggatc tgattttgga atgtgtggag
    27481 cgatttgttg aaccactgca cgttcagaaa ccgtatctga gaccacttct acgtcaaatt
    27541 gtttgaggta acgaagtcct ccgtgaacca attttgttga acgactagat gttccttctg
    27601 caaagtcttg catttcaatc aaaccagtct caagaccgct agctgccgcc tgcaaggcta
    27661 caccagctcc tgtgattcct ccaccgataa tcaagaggtc cagggtacgt tcctgcattt
    27721 ttttaattga caattcacgt gttttctttg aaaattccat atttacacac tttctaaata
    27781 aatcgcttta ttctgccagt attagtcgtc tacttccgca aagacttgag ttgctttcac
    27841 agccttcttc cagcccttgt agagttgttc cttgcgagat tcgttcatag atggctcaaa
    27901 gagttctcct gtctcgttca agagtttcaa ctcgtccaag tctttccagt accctactga
    27961 caaacctgct aggaaggccg ctcctagagc tgttgtttcc aggtttttag cacgtgcaat
    28021 gtcaatgcct aaaatatccg cctggaactg catgaggaag ttgttcatgg ctgcaccacc
    28081 atccaccttc agtacttgaa tggcggtctg agtatccact tgcatggtgt cgatgatatc
    28141 acgcacttga taagcaatag attgcaaagt cgccttgata aagtcttctt tgcttgttcc
    28201 acgagtcaaa ccaaagacgg aaccacgagc attttggttc cagtatggag cgcctagacc
    28261 tgtaaaggct ggaacgacat aaacttcatc gttgttgtga gaatcacgag cgtatttttc
    28321 agattctggt gaattttcaa ccatgcgaag accgtcacga agccactgaa tagcacttcc
    28381 tgcgatgaag atagaacctt ccaaggcata ataaacctta ccgttgattc cgtaaccaat
    28441 ggttgtcaag aggttgtttt cagacaactg catctcttcc ccagtattca tgatgatgaa
    28501 agagcctgtt ccataagtat tcttaaccat acctggctca aaagccaact gtccaaagag
    28561 ggctgcttgt tggtccccag ccatacctga gattggcacc tctccaccgt agaaatggaa
    28621 tggagctgtc ttgccgtaga tttcggagtt agaacgaact tctggaagta tagccttcgg
    28681 aatgttaagg atttccaaaa tctcatcatc ccatttgagt tctttaatgt tataaagcat
    28741 ggtacgagct gcatttgagt agtcagtcac gtgagccgca ccgtcagtca atttccaaac
    28801 caaccaagta tcgatagtac caaagagcaa ttcccctttt tctgctcgct cttgagcacc
    28861 ttctacatga tccaaaatcc aacgaacctt ggtagcagag aagtaagcat caataatcaa
    28921 accagtcttt tcatggaatt tttccacata accttggctt tttagttgct cagccaaagg
    28981 tgctgtctgg cgtgactgcc aaacgatagc attgtagata ggaagtcctg ttttcttatc
    29041 ccagacaacc gttgtttcac gttggttggt aatcccgatt gcctcgattt gatttggctt
    29101 gacaccactt tcgatgaaag cacccgcaat aactgactga acagagttcc aaatttcatt
    29161 ggcattgtgc tcaacccaac ctgcctgagg gaaaatctgg gtaaactctt tttgactcga
    29221 gctaaccttt tccccttttt tgttgaaaat gatggcacga gaacttgtag ttccctggtc
    29281 aatggccatg atgtattttt cttgtgacat gtactgtcct cctgataaag atcttgaggt
    29341 gtttcctctt tacacttact agtatacaaa ataaagcgct ttcttgttta tcaacttttt
    29401 ttaattttta aaaaaatgtg aggagattgt gtgaatttca caaaaaagac ctggattaac
    29461 caagcctttt aagtgaataa taactggcga atcgctacca aatcctccat atccaagtca
    29521 ttttttaaat aatagactgg tgtctgttcc ttcttatgaa tcgggttatt ggtaaccagc
    29581 aaatcataat gccgactagg gtcataagct tcaatggtaa taaaacgatt gtattccaaa
    29641 taccgtttca aaatggctgc catccttgaa aagacaagaa aaccagatgt caaatccaga
    29701 ccaatccgca tatgctggcc accgttttca gccatatatt cgattaactg gagccattcc
    29761 cagagaatct tcttatctaa atctgtcccc tgttgaaaag taggtagagc atgaaaaatc
    29821 tcctctgctg tctctttaaa atcatgttcc atcagtaaat atggatgacg attctctaac
    29881 tggtacttgt agcgatcctg taaaatatag cccttataga gatagacttg agcacaaagc
    29941 tgactgagtt cataggtgac atggtcctct gtataatccc ccaatagttc ctccttcttc
    30001 atttcttgaa tcaattgcgt cagtaaatct gccaactgcc ctccaaaacc aagaatatac
    30061 tccatagtat gaagaggaag aatgcgatga gataggagaa aagagaagaa tatcatcatc
    30121 tcaccatcct caactcctag tggaatatgt tgcccagcaa aaaaggacgg aacctttctc
    30181 agcaaacgaa gataaaagat attgtcaaaa taccctcgca ttttctcttc tatgacttga
    30241 aactgacaag cattgacccg aagacgttgt tgactgatgt gagcccagag aaccaagtcc
    30301 aatttctgcc ccacagacaa acttgcaccg cagatttcct ctaaattggc aatctcctgt
    30361 tttctctctg gtttctgcat gtgaccttcc cattcctgac tcgaccagac ctttcggaaa
    30421 agacagaaat agaaatagcg aatctgatgc tctggacctc gccaacgtcc attttggatg
    30481 gataaatcaa attctgacag aatctgattt aaaccagcca agtgacgacc aagcgtagcc
    30541 tcgctaatca ccaattcttg agccagctga tgggctaaaa actgttggtg gtagagaaga
    30601 taaaccaaaa tctggtattt aacagcactc tccaaaaata agctccgaat atctctcccc
    30661 ttggtagctg caccgataga cagacgcaaa ttttcatttt ctgagtgaat agtcagctct
    30721 aagccactat ccaaagcctt gtcattgagc agggtgacat atttggttag ggttgctttt
    30781 gaaaatcctg tttcttccat tacagccttg acggtcgtct gagactcttg taatagaaag
    30841 gaaaggattg aaaattgacc acactcagct ttctccatca aatctcctaa atacatttgt
    30901 tacccctttc attttctacc ttaagcatag cataaatctt acaaatgctg aaataatctg
    30961 tttctctttt tattttcatg ctgatttcct ggtccattat cctgaaaatc agtaaacaca
    31021 cggctccccc tctgggcatt tttatgctaa aatagtagct atgaataaaa ttattaaaac
    31081 tatatcagaa agcggagcct ttcgtgcttt tgtccttgac agcacggaaa ccgtccgcac
    31141 tgctcaagaa aaacaccaaa cccaagctag ctcaactgta gcgcttggtc gaactcttat
    31201 cgctagccag attctcgcag ccaatgaaaa aggaaatacc aaacttacag ttaaggtgtt
    31261 gggatctagc tctctaggtg ctattatcac cgtcgctgat accaagggga acgtcaaagg
    31321 ctacgttcaa aatcctggtg ttgacatcaa aaagactgcg actggtgaag tcctagtcgg
    31381 accttttgtt ggaaatggtc aattcctcgt tatcacagac tacggtactg gaaatcctta
    31441 caactctata actcccctca tctccggaga aatcggtgaa gaccttgcct tttaccttac
    31501 tgaaagccaa caaacgcctt cagcggtcgg cctcaatgtc cttttggacg aggaagacaa
    31561 ggtcaaggtt gcaggtggtt tcctagttca agtcttgcca ggagccaaga aagaagagat
    31621 tgctcgcttt gaaaaacgca tccaagaaat gccagctatc tctactcttc tcgaaagcga
    31681 cgaccatatc gaagccctcc tcaaggctat ctacggggac gaagcctaca agcgtctttc
    31741 tgaagaagaa atccgtttcc aatgtgactg tagccatgaa cgctttatga acgctcttgc
    31801 cagccttcca agctcagact tacaggaaat gaaagaagaa gaccacgggg cagaaatcac
    31861 ttgtcaattc tgccaaacta cttacaactt tgatgaaaag gacctggagg aactcattcg
    31921 tgacaaatct taatacacct tttatgattg gcaatgttga gattcccaat cgtaccgttt
    31981 tagcgcctat ggctggcgtg accaactcag cctttcgtac catcgcaaaa gagctcggag
    32041 ctggactcgt tgtaatggaa atggtctctg acaaaggaat ccaatacaac aacgaaaaaa
    32101 ccctgcacat gcttcatatc gatgagggcg aaaaccctgt ctctatccaa ctttttggta
    32161 gcgatgaaga cagcctagca cgcgcagcag aattcatcca agaaaacacc aagaccgata
    32221 tcgtcgatat caacatgggc tgccctgtca acaaaatcgt gaagaacgaa gctggagcta
    32281 tgtggctcaa ggatcctgac aagatctact ctatcatcaa caaggttcag tctgtccttg
    32341 atatccccct tactgtcaaa atgcgtaccg gatgggcgga cccatctctg gcagtagaaa
    32401 atgccctcgc tgctgaagct gcaggtgttt ctgccctcgc catgcatggc cgtacccgtg
    32461 aacaaatgta tactggccac gcagaccttg agacccttta caaggttgcc caagctctaa
    32521 ccaagattcc attcatcgcc aacggtgata tccgtactgt ccaagaagcc aagcaacgca
    32581 tcgaagaagt tggtgctgac gcagtcatga ttggccgagc tgccatggga aatccttacc
    32641 tcttcaacca aatcaaccat tactttgaaa caggagaaat cctacctgat ttgacctttg
    32701 aagacaagat gaagatcgcc tacgaacact tgaaacgatt gattaacctc aaaggagaaa
    32761 acgtcgccgt tcgtgaattc cgcggcctcg ctcctcacta tctccgtgga acatctggcg
    32821 ctgccaaact ccgtggagcc atttcacaag ctagcaccct ggcagagatt gaagctctct
    32881 tgcaattgga gaaggcttaa tagtttaaaa cccgtaactc tcttaaagag tctcttgagt
    32941 gccgccattc tttcctcatc aaaaaaactc cgtagtctct agcgccataa atccggctag
    33001 agattacaga gttatttttt aatctaaact tcctacaagg gtatagtatc tactgaaagg
    33061 atatggtatt tgtagggaat actttaaaga gttcttacag gaagccagca ttaacgagtt
    33121 acattaggtt tagtttaccc atttaccatt ggcattgact ctatagccac ctacagttgt
    33181 gttgactgca agggcacctg agccattgac atagtaccat ttgtctgata ctttgaacca
    33241 ttggctttct ttcatagccc ctgatgcttc aagatagtac catgtatctc catctttcag
    33301 ccaacctgtt gccatcgaac cgttagcatt
//
LOCUS       DAVHLA010000021        33326 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVHLA010000021 DAVHLA010000000
VERSION     DAVHLA010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33326)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33326)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33326
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.021"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(372..1352)
                     /locus_tag="VVO77_001121"
     CDS             complement(372..1352)
                     /locus_tag="VVO77_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HEU5693141.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTPPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            complement(1668..3683)
                     /gene="recG"
                     /locus_tag="VVO77_001122"
     CDS             complement(1668..3683)
                     /gene="recG"
                     /locus_tag="VVO77_001122"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEU5693142.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQTLKSENRVQGSGLVLDWSQEKVTAVKASLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            complement(3702..4805)
                     /locus_tag="VVO77_001123"
     CDS             complement(3702..4805)
                     /locus_tag="VVO77_001123"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEU5693143.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            complement(4795..5163)
                     /locus_tag="VVO77_001124"
     CDS             complement(4795..5163)
                     /locus_tag="VVO77_001124"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEU5693144.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            complement(5202..6233)
                     /locus_tag="VVO77_001125"
     CDS             complement(5202..6233)
                     /locus_tag="VVO77_001125"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEU5693145.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMELENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEVFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            complement(6235..7266)
                     /locus_tag="VVO77_001126"
     CDS             complement(6235..7266)
                     /locus_tag="VVO77_001126"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEU5693146.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            complement(7347..9860)
                     /gene="secA"
                     /locus_tag="VVO77_001127"
     CDS             complement(7347..9860)
                     /gene="secA"
                     /locus_tag="VVO77_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEU5693147.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQSMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            complement(10006..10293)
                     /locus_tag="VVO77_001128"
     CDS             complement(10006..10293)
                     /locus_tag="VVO77_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693148.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLTFFFIPWDRAILGVRIDIFI
                     IQKILLAFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            complement(10304..10954)
                     /locus_tag="VVO77_001129"
     CDS             complement(10304..10954)
                     /locus_tag="VVO77_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU5693149.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGNNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGVKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISKDISDLCTDVLAVENGHIQYVKDIQS"
     gene            complement(10958..11599)
                     /locus_tag="VVO77_001130"
     CDS             complement(10958..11599)
                     /locus_tag="VVO77_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693150.1"
                     /translation="MFKNFNNILLKRKIVLLLRIVLMMILINHLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEVNLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLILSRLEEKFKKG"
     gene            complement(11592..12383)
                     /locus_tag="VVO77_001131"
     CDS             complement(11592..12383)
                     /locus_tag="VVO77_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693151.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAILTHFFGTFSPLGWNSLFSDGSSLQR
                     LLDGEITSYLFFTCVLLIGIFINAVYFLQIVDYLGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLEKYEDNV"
     gene            complement(12568..12903)
                     /locus_tag="VVO77_001132"
     CDS             complement(12568..12903)
                     /locus_tag="VVO77_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693152.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNVADIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGGRH"
     gene            complement(13043..13378)
                     /locus_tag="VVO77_001133"
     CDS             complement(13043..13378)
                     /locus_tag="VVO77_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693153.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            complement(13469..14779)
                     /gene="der"
                     /locus_tag="VVO77_001134"
     CDS             complement(13469..14779)
                     /gene="der"
                     /locus_tag="VVO77_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEU5693154.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            complement(14793..15506)
                     /locus_tag="VVO77_001135"
     CDS             complement(14793..15506)
                     /locus_tag="VVO77_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEU5693155.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            complement(15503..16399)
                     /gene="dnaI"
                     /locus_tag="VVO77_001136"
     CDS             complement(15503..16399)
                     /gene="dnaI"
                     /locus_tag="VVO77_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEU5693156.1"
                     /translation="MESVGDVLKRQPSRFHYQDLVQKIMKDPDVAAFVQQESLNQDEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVMNHGYADVSYEETPELIAAEKEAA
                     IKKRLNLINFPSSLKNVSFLDVYRDDVQRLTVLKRMIEFVNDYPNNLKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTVWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            complement(16400..17569)
                     /locus_tag="VVO77_001137"
     CDS             complement(16400..17569)
                     /locus_tag="VVO77_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEU5693157.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLVLHAPLSSQD
                     FLEHPVYRRLLEKKIGDVAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLDHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     EQKAKTQKQNQTAPAKTNIPKWSNPEYKNTSSAEELEEMERQTLELLAKLDNGGD"
     gene            complement(17570..18043)
                     /gene="nrdR"
                     /locus_tag="VVO77_001138"
     CDS             complement(17570..18043)
                     /gene="nrdR"
                     /locus_tag="VVO77_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEU5693158.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            18183..18548
                     /locus_tag="VVO77_001139"
     CDS             18183..18548
                     /locus_tag="VVO77_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU5693159.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            18553..19248
                     /locus_tag="VVO77_001140"
     CDS             18553..19248
                     /locus_tag="VVO77_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5693160.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            19265..20032
                     /locus_tag="VVO77_001141"
     CDS             19265..20032
                     /locus_tag="VVO77_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693161.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(20385..21584)
                     /locus_tag="VVO77_001142"
     CDS             complement(20385..21584)
                     /locus_tag="VVO77_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5693162.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHIQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(21581..22474)
                     /locus_tag="VVO77_001143"
     CDS             complement(21581..22474)
                     /locus_tag="VVO77_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5693163.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            22590..22670
                     /locus_tag="VVO77_001144"
                     /pseudo
     CDS             22590..22670
                     /locus_tag="VVO77_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            23155..23368
                     /locus_tag="VVO77_001145"
                     /pseudo
     CDS             23155..23368
                     /locus_tag="VVO77_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            23783..24400
                     /locus_tag="VVO77_001146"
     CDS             23783..24400
                     /locus_tag="VVO77_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEU5693164.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(24720..25607)
                     /locus_tag="VVO77_001147"
     CDS             complement(24720..25607)
                     /locus_tag="VVO77_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU5693165.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGENIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(25756..27639)
                     /locus_tag="VVO77_001148"
     CDS             complement(25756..27639)
                     /locus_tag="VVO77_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU5693166.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYALADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVSKGDAVIE
                     VKI"
     gene            28016..29470
                     /locus_tag="VVO77_001149"
     CDS             28016..29470
                     /locus_tag="VVO77_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEU5693167.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEHPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            29451..30416
                     /locus_tag="VVO77_001150"
     CDS             29451..30416
                     /locus_tag="VVO77_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU5693168.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTELRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(30451..31725)
                     /locus_tag="VVO77_001151"
     CDS             complement(30451..31725)
                     /locus_tag="VVO77_001151"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEU5693169.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(31725..32897)
                     /locus_tag="VVO77_001152"
     CDS             complement(31725..32897)
                     /locus_tag="VVO77_001152"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEU5693170.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            complement(33028..33276)
                     /locus_tag="VVO77_001153"
     CDS             complement(33028..33276)
                     /locus_tag="VVO77_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693171.1"
                     /translation="MVSSWGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
BASE COUNT         9778 a         7443 c         6308 g         9797 t
ORIGIN      
        1 acggcaaggc gaagctgacg tggtttgaag agatttttga aaagtattaa cacctacaga
       61 caagcctaac gatagcaaga actaccctac tcgataggta tcggcttttg ctttctgaaa
      121 aaaattattt taagcaattt gacaaatcta gcaacaaaaa attctataaa tataatagat
      181 tgaaactaga atagtacaca tctacttcta aaacattgtt agaaatcgat ttgactgtcc
      241 tgatcgattt gtcctattct tgtttcattt tactatattt ccatgataaa acgcatagta
      301 tcaagttttt ttaatcccct gatactatgc gtgtttgtaa tttttaagat tttgtgctta
      361 gagtcgactc cttattttag atatttaaaa ggaatctcac ttccacagag ccagttgtag
      421 acttggtcat tgacaaatac attcatggct tcgtgagcat actcaggcat gatacgatag
      481 gttttatcgc aggtcagacg attataaatc gcaaactggg taatgggata gcaaacatcg
      541 tcgtccaagc ccgtaatcat cttaacctca ccttggatac gatgggcaag atttttgaca
      601 tcgatatagg caagggtcgc catgatttcc tcctctgttt catggaaggg gtcgtgaaac
      661 ttgaaataac ggaaaagttc gtcgtaagcc tcgctagtat taccaatctc aatcacccgt
      721 ctgaagtctg acaagaaggg ataaatggca actgttttct gaattcgagg attgagcgct
      781 gctgcaacta gagctagagc ccctccttgt gaggcaccat agctagaaag acgcttctca
      841 tcaacctgag acagactagc aacaatttcg accaactggt aaatatccag ataaacatcc
      901 ttataaaaga ggtggtcccg accttccata gcaccacgga taatatgccc cttcacggta
      961 tttcctaaag gagaacgcaa gccgtcttgt gagtaacctg actggccccg cacatccatg
     1021 gaaacaacac cataaccagc tacggtgaag cccagcatgt cggcccagtc ccagccacgt
     1081 cccatataac catgaaaatg gaagattagt ggaaccttct cctcactctt tggaagaaca
     1141 atgcgtgcat agacctttcc ttccttgctt ccttcaaatg ttaactcata gcacttgact
     1201 tgaggaatgt ggaaatctct ttcctccaag tggtaggatg gaggtgtgga aacatttttc
     1261 acttccccat cccagaaagc atcaaagtct tccggaacct catcccttcc tctataggtc
     1321 ttaatttctt ctagcaaagc tggatttttc atagcatgct ccttttattt tgtaatcgtt
     1381 accacaactg tagcatatct atgtaatcaa tgcaagaaag aaggataaat agaaagtgaa
     1441 tttagattct ttacttttag gatgatgggc tgaaagtagt tttagaaacg aaaaagagca
     1501 tttcgctctc tcttctgttt atactagttt tttgcttcct tcttttggaa agtggtttgg
     1561 taatttactt taatcgttac tgtcatatga gagtcctcgt ttctttttga tgactttagt
     1621 ataagagcca aacctaaaaa ctagcttaag ttttccttag agaaagctta atccagatgt
     1681 tctttctttt ccagatgaag ggcaatcatg cgccactctg gatcttcttg ccaagcttct
     1741 atagaactaa tgtagctagc aacctttctt gcttcttcta aaatcggaaa atcttcgata
     1801 atatcagcca cttggaactc tggaagtcct gactgtctgg ttccaaaaat ctcaccagaa
     1861 ccacgcattt tcaaatcttc ctccgcaagg acaaatccat tggtcgtttc tgtcatgatg
     1921 cgcatgcggt ctttcccaga atccgtcttg ggattggcaa cgagaacagc gtaggactgc
     1981 ttgtcccccc gaccgacacg acctctaagc tggtgaagtt gactgagacc gaagcgatcg
     2041 gcatccatga taatcatgac agtcgcattg ggaacgttga ccccaacctc aataaccgtc
     2101 gtcgaaacca gaatatccgt ctttctctcc ttgaaatcct gcatgatctg gtctttttcg
     2161 tcactcttca tcctaccatg tagaagagcc acctctgcct tgcctgcaaa atgagtcgtc
     2221 aactcctctg ataaggcaat ggcatttttc aaatctagag cttctgattc ttcaatcaaa
     2281 ggagagatga cataggcttg ggaacctttt tgaatttccc cctctaacca agtcaagacc
     2341 tgaggtagtt gctcatgttt gatccagcgc gtcacaatag gcttccgacc tgctggcatc
     2401 tggtcgataa tggaaacatc catatctcca aaggctgtga tggcaagcgt ccgtggaatg
     2461 ggagtcgccg tcatcatgag gacatctgga ttgtcacctt tttcccgtaa aatacgcctt
     2521 tgccctacac caaaacggtg ctgctcatcg ataataatca aaccaagacg agcatactcc
     2581 accccatctt gtatcagagc gtgagttcct ataatcaaat cagcctcacc cttggcaatg
     2641 gtctccaaga cttctctctt ttctgcagct ttcaaggaac ctgtcaagag agccagtttc
     2701 aaattgggaa aaaggttctg taaactctca aagtgttgct ctgcgaggat ttctgttggt
     2761 accattaggg cagcctgata acctgctgtc actgccgcaa acatggccaa gccagcgact
     2821 accgtttttc cactccccac atctccttgt aggagacgat tcatgtggtg gtcggacttc
     2881 atatcagtta aaatttcctg caaactcttt tcctgagctt gggtcagggc aaaaggaaga
     2941 cttgctttaa ctgctgtcac tttttcctga gaccaatcca gaaccagacc acttccctga
     3001 actctatttt cagacttgag cgtctgcagc tgcatttgga aataaaagag ttcctcaaac
     3061 ttgatacggc gaagagcctg cttgtattct gccaaatcct ttggaaaatg catagctcgg
     3121 actgcctgac aacgggacat gagtttgtat ttgtctagta aagactgggg cagattttct
     3181 tctatcaaga ggtccagtcc ctgatcaaaa gccgtcttga tgaccttgac cagactggcc
     3241 tgactgattc cctgagccag acgatagaca ggctggaggt catcttctac ctgagccaga
     3301 accttcatcc cagtcagact agccttagcg cggtcccatt ttccaaagac agcaagggtt
     3361 gctcccaact ctattttatc agccagatag ggctggttaa agaaattcac cgcaaaaacg
     3421 acctctccct gcttgagact aaaacgcagg cgattgcgct tgaaaccata atactggaca
     3481 ctagcaggag tcactacctg accagaaaga actgccttct caccgtcttc cagctccagc
     3541 acctgcttgg ttttgaagtc ttcataacgg aaaggaaagt agagcaagag atcttgcaag
     3601 ttttcaattc ctagtttggc gtatttttct gctgactttg gtcccacacc aggcaagaca
     3661 tgcaagggtt gatgtagatt catgctccac tcctttcttt tctaataata ttctctcgga
     3721 atacggtcgc tgaggaggca aaccacctca tagttaatgg ttacgcggta ggtcgctacc
     3781 tgagttgcag tgatttcctt atccccattg gagccaatca aggttacctt ggttcctagc
     3841 ggataaagct taggcaatcg aatagtgatt tggtccatcg aaaccctgcc gacaattggg
     3901 caagcttggc catctaccaa gacagagaaa ttttgcatgt ctcttgtcca tccatctgca
     3961 tacccgattg gcacggtcgc gatgacttgc tcgctatccg cttgataagt tgctccatag
     4021 cccatgcaag ctccagctgg aactgtcttg acatgaacca gagcagactc caaggtcaag
     4081 gccggtatca aatcataagg caaatccaag accgctccac ttggattgag gccatacatg
     4141 gcatctccca tacgaaccgc attgaaaata gtctctacat gccaaagagt cgttgcagaa
     4201 ttgctagcat gaaccagctc tggaacttcc ttcatactag ctaaaatagt tttaaaccgt
     4261 tctaactggg cattaaaata gtcatctgat tcctcatcag cagtagcaaa gtgggtaaag
     4321 attccttcaa cacgaacacc gtgttgttgt agcaaatctt gagcctgctc aacctcactg
     4381 gcctctctaa aaccaatccg tcccatccct gaatcaatct tgaggtggac tgtcaatcca
     4441 gttaggtcca cttccttatc taagagtgct tgaatccact ccagtccagc cactgtcaag
     4501 gtgaagtcat attctttagc tagagcaaca gcttcgattt cagaaactcc taaaatgagg
     4561 attggcttgc tgagtccagc ttgtctgagt tcaatggctt catcgatatt ggaaacgcaa
     4621 aagccatcaa catcatcttg aattgccttg gcaacggcaa cagctccatg accataagca
     4681 ttggccttga ccacagccaa cttgagcgtt ccttgaggga tatgagcccc catttgctga
     4741 atattttgtc gaatagctcc cagatgaatc agagccttgg ttggtctatg tggactagct
     4801 ttcatgattt tcctccaaaa tgacactggc tgtcacaaac tgatcggtgt ggctgataga
     4861 cagccaaatc tttcctgaaa atggtgcctg actaaaataa ggcgccccac gttcattgtt
     4921 caagacttcc aaatcctgaa aaccgagctt gctaatgccc gttcccatag ccttggaaaa
     4981 ggcctcctta gccgaccagc gaccagctaa atattctatt tgcctgcgtc ctttgagact
     5041 ggtgaagcgc tccatttcct gagcggtcag tacacgctta gcaaatcctt catgtcgtgt
     5101 aactgcgctt tctatcgaag ccaattcttc gatgtcaatt ccgtgtccaa ctatcattct
     5161 catcaaaagg agttgagatt ccccaactcc atccttttca cttattttgt caaggtaaca
     5221 taaatctctt ctaccaaggc ctctgtattt tcccaaccta ggcaagggtc agtaatagag
     5281 caaccaaaga cctctggttg gttttgacga ccatctgcta ggtaagattc aatcataaat
     5341 cctcgaaccg tctttttaat tttctcattc caatcacgat tctgcaaggt ctggcgaaca
     5401 attcgaatct gctccatata ttgcttgcct gagttatcat ggttggtgtc aatgaggata
     5461 aaaggatttt caagttccat ggtttcatag cgttcaatgg cttggagtag gttttcatag
     5521 tagtaattcg gcatataatt gccatactcg ttgactgctc cacggaggat aacatgggcc
     5581 aaaggattac ctgatgtctc aacttcctgc ccatgataaa ggaaggtttg cttgttttga
     5641 gcagcataga tggcgttaaa cataacaccc aaatttcctg aggttggatt tttcatccct
     5701 actggtgcat caatcccaga agccacaaag cggtgctctt ggtcttccac agaacgagct
     5761 ccaacggcat ggtagctgac caagtcatcc accaagatca gatttgacgg ataaagcatc
     5821 tcatctgccg ttgtcaaacc agtctctgta atcacgcggt agtgcaactg gcgcacagcc
     5881 tgcaagccgt taatcaggct tggagcctta gaagtatctg gctggtgaac caatccttta
     5941 tagccgtctc cattggtacg aggcttagca gtatacacgc gcatgaccat gaaaatcttg
     6001 tccgctacct tcttttgcaa ggcggataaa cggcgagcat attccaagac cgcctcttca
     6061 ttatcagaag agcaaggacc aatcaccaag agaatacggt catcttcccc tgaaataata
     6121 tctgccaatt ccctgtcacg gctttccttg agtctcaagg cttccgcaga caattgggtt
     6181 tcagccttga tgacttccat atcgatttct tgaccttttt caataaatgc catcttattc
     6241 tcctaacgtt ttgtaaattt ctctgacaag agcttctgtg ttatcccaac ccaggcaagg
     6301 gtctgtgata gacttaccaa atacttctgg ctcattttgt cgaccatctt ccagataaga
     6361 ctcaatcata aaaccacgaa cgaactgctt aattttttca ttccaagcac ggttaatcaa
     6421 ggtctggcgg acaattcgga tctgttcaat atactgctta ccagaattgt catgattggt
     6481 atcaatgatg ataaaaggat tttccaagcc cattttctca tactgggcaa tggtatcaat
     6541 taaattgtca taatagtagt tgggaatatt ttttccatac tcattaagag caccacgaag
     6601 aatagcgtgt gaaagcgggt tcccagttgt ttctacttct tttcctaaga aaaggaaact
     6661 ttgtttgttt tgagcagcat aaatcccatt aaacatgaca ttgagatttc cagaggttgg
     6721 atttttaaaa ccagtagaaa atcctgcccc acttgccaca aagcggtgtt gctggtcttc
     6781 aactgaacgg gcaccaactg ccatgtaaga aatcaaatca tctacaagcg gaaggttttc
     6841 aggataaagc atttcatcag cagttgtcat ccctgtttct gtgatgacac gatagtgaag
     6901 atggcgaacg gctttgattc cattgataag actaggcgct tctgtcgcgt taggctggtg
     6961 aatcaagccc ttatagccat ctccgttggt acggggtttg gcagtataaa cacgcataac
     7021 cataaagata cgatctgcca cttcttcttg taggactgcc aaacgcttag cgtattcaag
     7081 gacagcttct tcgttgtcag atgagcatgg cccgattacc aagagaattc gctggtcttc
     7141 tccacgtata atggcttcta gctcttgatc tcgctgtgat ttcctctcca aagcctgacc
     7201 ttctaatttt gacaaggcac gaacttcttc tatatttatt ttagagcttt ttgctgtaaa
     7261 taccataact catctcctta taaagcaaac ggatacccag taaaaattta cttttcacaa
     7321 gatatccgcc tctaaactat ctcattttat tgtcttttac cgtgacagtt tttaaatttc
     7381 ttaccagaac cacatgggca aagttcattg cgtccaatct ggctcaaatc caaatcttct
     7441 ggcatacttg cttggtgagc agcgatattg cgagtcgctg ttgtactgat atgacgttct
     7501 gcctgtggtc tttcttgttc atgaatttgt gctttcatca tcaagcgtgt cacatcaaac
     7561 tcaatcgaac caatcatatc attaaacata cggaaacctt ctgcctgata ctcaacaaca
     7621 gggttgttct gagcatagcc acgaagtcca accgcgttac gcaattgatc aagggcatcg
     7681 atatgatctg tccacttgtt atccaccact cgtagaatca aaactttttg gaattcttta
     7741 actgcttctt catcgcgtag ttttgaaacc tgactatcgt aaaccttcaa ggcacgttgg
     7801 aaaagctctt ccttgatggc cttatcagac aagcctgaca agtcttccat cgtaatagaa
     7861 tcttcaggaa gcaagttgta cttagcaaag ttcaaaattg cctctagttt ttcatcttgt
     7921 ttggcacgcg catgaccatc aacgacacgt tcaatcgtgc gtttgatcat agactgaatt
     7981 tcaggtgcca agtcacgatc tgcagtgatg acatcgtaac gttgagcata gataatctca
     8041 cgttgttcac gcatgacatc atcgtattga aggacttgtt tacgggtatc gtagttattt
     8101 ccttcgacac gtttctgagc tgcttcaacc tgacgcgtca acatgcgaga ctcaatcgcc
     8161 tcttcagaca tgttcaagcg ttcaaagatt cccttcaagc gttcagaacc aaaacgtttc
     8221 atcaaatcat cttcaagaga taggtagaat tgtgactcac ctggatctcc ttgacgacct
     8281 gaacgtccac gaagctggtt atcgatacga cgactttcat gacgttctgt accaataaca
     8341 caaagtcctc caagttcacg aacaccttca ccaagcttga tgtcggtacc acgacccgcc
     8401 atgttggttg cgatggtaac ggcaccacgt tgaccagcat tcatgatgat ttgggcttct
     8461 ctatagtggt ttttggcatt caagacttcg tgaggaacac cagctgcaac caatttctta
     8521 gaaatgtagt cactagtttc aaccgctact gtaccaacca agacaggttg acccttttgg
     8581 taacgagcct taacgtcttc gacaaccgct ttaaacttag attctatact tgcataaaga
     8641 aggtctgagt ggtcaatacg ttgaacagga cggtttgttg ggattggaat aacacgaatg
     8701 ttgtagattt cacggaattc ttcttcctca gtcttacctg tacccgtcat accagacaat
     8761 ttcttgtaca tacggaaaag gttttggtac gtgattgagg cagatgtctt ggtttcatcc
     8821 tggattggca caccttcttt ggcttcaata gcttggtgca atccatcaga ataacgacga
     8881 ccttccatgg tacgacctgt aaattggtcg acaatcaaga tttcttgctc ttcgctcacc
     8941 acatagtcaa tatcgagaag catgatgtag ttggcacgaa gggcgttatc gataaagtgg
     9001 gtcaaagcca cgttttcgat gtcatagagg ttttcaagtt tgaagtagct ttcagccctg
     9061 tcaatccctg aatcagacaa accaatagtc ttagactgca catcgatgat gtagtcatct
     9121 ttgttcaaag attttacata gtggtctgcc atgtgataca actgactggt ttcaaccgca
     9181 ttggcacctg atacaatcaa aggtgtacga gcctcgtcaa tcaagataga gtcaacctca
     9241 tcgaccaagg catagttaag cggacgttgt accatgtttt cagcgcgaac gaccatattg
     9301 tcacgaaggt agtcaaatcc gatttctgag ttagttgagt aagtaatatc acactcatag
     9361 gcttcttttt tctccattgg agatttggta gccaagttaa tccctactga caaaccaagc
     9421 caagagtaca attcacccat ctcagtcgcg tcacgttctg acaggtattc attaaccgta
     9481 actacgtgaa cccctttacc tgaaagggca ttgaggtata ccggcatggt cgcagtcaag
     9541 gttttccctt cccctgtacg catctctggc acgtcaccat ggtgaagaac aatccccccc
     9601 atgacctgaa ccttataagg gaagagacct aggacacgtt tggcaccttc acggacaacc
     9661 gcaaatgctt cgtaaagcaa tgaatccagt gattctccat tttgataacg ttccttaaat
     9721 tcaactgttt ttgcttttag ttggtcgtca gtcaaagcag ccatttggtc ttcgtatttg
     9781 aaaaccttgt cagccatctt ttccagacga cggatttctc ctttatcatt ttcgataatt
     9841 gtttttaaaa tattagccat gtttttcctt actttaaatt ccgaatattt tagaatgttc
     9901 ctttaatttt agcacaatta ctgattattt tcaaggaaga atccccattt tgaaaaggaa
     9961 aaagaggtta gttttcaagc taacctctcc gacttttatg atgctttaat tgccaaaaat
    10021 cggcaaaatg gcaaatgtga taaataagtt aatccaaaga gaaagacagc aaatcagtcc
    10081 aaaaacaaag agactgactt tcttggacag caaggccatc aaaatggaca gaattccaaa
    10141 agctagcaag attttctgta tgatgaagat gtcaatcctt acccccagaa tcgctctatc
    10201 ccaagggata aagaagaaag tcagccagat cagcagaact aaaccaatat aaaccttgga
    10261 atagcgtgta ataaatgatt ttagatgtgc cataagccat ctcctaggat tgtatatcct
    10321 ttacatattg tatatgtcca ttttcgacag ctaatacatc tgtacaaagg tctgaaatat
    10381 ctttcgatat gtgcgacgtc aggataacca gaccattttc ttttttcagg taagataaaa
    10441 tgacctgttt ggttaacctc acactcttct catccaaagc attcataggt tcatcgagaa
    10501 agagtataga aggagaggaa ataaaggctt gaatcaaggc cattttttgc tttgttccca
    10561 aggataaatg acggtattca acgtcttcaa attcctgtaa atcatagtat tgaatccaat
    10621 aggcaattct tttttccgta actttagatg aaaaatacct taacagttcc aaattttctc
    10681 tcagggataa atgagataaa aactcgactt tttcaattaa aattcctgca tcctgaatat
    10741 aatgattttt taccccgtaa actttaccat cttgaagaac ttttcctttg tcaagcttaa
    10801 tataaccagc aagtatcttt aaaagaaccg tcttgccaga tccattatta cctttaagtc
    10861 cataaatttt tcctgattga aacaccaaat tcaactgatt taaaataggt cttttcccat
    10921 aaattttctg tccatttata atttcaagtc tcatcgttta tcctttctta aatttctctt
    10981 ccaagcgact aagaatcaac ataactaata agcttaagag tactaaatac actgttacaa
    11041 tatgatccat catccattct tgtcccacaa atgccaaaaa atagagaaaa aaagaaaaac
    11101 cagcgcccgc actaatcagt gctatcagat aagacagtag taagtacaac atcattaact
    11161 gagcaagtaa aaagaaaagt gcgactgttt tgaaatgaat tcctagagga agtaaaccaa
    11221 gaaaccagac aaacaaatct tgagtaaaaa atttagaaat gacaaccaat cgtttccttg
    11281 tataatcgaa aaaggagctt gattgatagc gaatcaagtg atggtaatgg tctgccaaat
    11341 cactttcaag taaaatgaca gagagccatc ctaccatgaa aagcgaaagg tttaacaaga
    11401 gtttggggat ttctaaattc acttcagaat agtcattata ggaaaaaatt gaaatcaatt
    11461 ctctcttgaa aaagataaca gcatcctgct tttgaaccgc tgttgacaat agatggttta
    11521 tcaaaatcat catcagaact atacgaagta gtaaaacaat ctttctcttt agcaaaatat
    11581 tgttaaaatt cttaaacatt atcttcatat ttttcaagca ccatgtaagg gacaatataa
    11641 aggatataag gagtaaagag tttcatcaaa cttacatccc catagctagc ttgcatcaaa
    11701 ctcgtcatag gaaccatata gtaaggcaag gcactataga gcagcataga accaagccaa
    11761 agaaacatca aataggtgat tgccgaacga gtcacatttc ctaaataatc aactatttgt
    11821 aaaaaataga ctgcattgat gaaaataccg attagtagga cacaagtaaa gaacaaatag
    11881 cttgttatct ctccatctag gagcctttgt aaactactcc catcagaaaa tagagaattc
    11941 catccaagag gagaaaaagt cccaaagaaa tgagttaaaa ttgcaattat cagcacagtc
    12001 actaaatata tcaaacaagg gatacttgca acttgcaaag tcaactttct ttttaaccct
    12061 tgataactca cttctcttcc aatactcaat cgtaaaactt tatttttcag ctcaatatat
    12121 tgaaaaccta gcaaaacaat gatgattgga ataataaatg attgataaaa acctagattg
    12181 aactggagaa tacgaaaatc taatgctgat tttaataagt catttttaat tgcttgtcca
    12241 tcgaatttag ctagatcggg cgcatgaata tcaaaaaaga aataagtcat caaaacatca
    12301 cgataaacca aagcaagaaa aagcaaagta agcaagacat aaacaaattt atgccttgcc
    12361 aaagttaaga gaggaatctt cataagccac ctcctacaaa tagaaagtaa tataatactc
    12421 aatgaaaatc aaagagcaaa ctaggaaact agccgcaagt tgctcaaagc actgctttga
    12481 ggttgtagat aagactgacg aagtcagtta catatataat ccaaggcgac gttgacgtgg
    12541 tttgaagaga ttttcgaaga gtataaatca atgccttccg cctttagact tccctagttc
    12601 ccgtctcaag tcaagcattt ttttgaaaca gatatagtct aaccagtcac tagcaaaagc
    12661 gataagtagt aataatagcc aaatacccca taacttgatg tctgccacat ttctcaagac
    12721 gatattgaaa aacagaactg aaaaaactgt ccaagcaagg ctaaaaagag catagagggt
    12781 gatgtaaatc cagtaaaaat agtaaaaaat tgggaaaaat ttactttctc tattatcctt
    12841 gtcaatccag ctgaaaaagt aaaaacaggg taataagatt atcattttaa acaagtgttc
    12901 catcacaagc ctcctttttt aaattgtttt ctttagtttc gttctattaa atgttattac
    12961 caatataaac cttggaatag cgtgtaataa atgattttag aggtaccata agccacctcc
    13021 tacaaataga aaccgatata aatcaatgcc ttccaccctt agacttccct agttcctgtc
    13081 tcaagcgaaa catttctttg aaacaggaat aagttaacca attcatacca atagctagca
    13141 gaataaaaag aaaccaaatg ccccataact tgatatctgt cacatttctc aagacggtat
    13201 tgaaaaacag aactgaaaca actgtccaag caaggctaaa aagagaatag aaggggatgt
    13261 aaaaccagta aaaataataa aaaattggaa aaaacttact atttctgttg gccttctcaa
    13321 tccagttatc aaaataaaag tacggtgcta aaagtaagaa tttaaacaaa tgttccatca
    13381 ccgacatcac cctccttctt ttgatagcgt tttctattat tttattatat caaaaaaatc
    13441 cggaactgtc attccagatt ctactttttt atttgcgttt tcttgcgatg agatgaatcg
    13501 gtgttccctc aaaaacaaag gccttgcgga tttgattttc caagaaacgc aggtaagaaa
    13561 agtgcatgag ttcttcttca ttgacaaaga tgacaaaggt tggtggtttg gttgccactt
    13621 gggtcgcata gaaaatcttg agacgttttc ctttgtctgt cggtgttggg ttgatggcaa
    13681 tggcatccat gatgacatcg ttcaagacag ctgatggaat acgtgtattt tgactttcgc
    13741 tgatttgctt aatcatctca ggaagtttgt ggagacgttg cttggttaaa gctgatacaa
    13801 agataatcgg tgcgtaaggc aggtattgga actgctcacg gatatcttct tcccagtttt
    13861 tcatagtgtg gttatctttt tcaagcgtat cccacttgtt gaccacgata atcatccctt
    13921 taccagcttc atgggcaaat cctgcgatac gcttgtcgta ctcacgaatg ccttcttccg
    13981 cattgatgac catcaagacc acatctgaac ggtcaatagc acgcatggca cgcataacag
    14041 agtatttctc agtattttca taaaccttac cagacttacg cataccagcc gtatcaatca
    14101 tggtaaactc ttgaccatct gtatctgtaa agtgggtatc aatggcatca cgagttgttc
    14161 cagcaacagg actagcaata acacggtctt ctcccaagat agcattgatc aagcttgatt
    14221 ttccaacgtt aggacgacca atcaagctaa acttaatgac atctggattt tcttcctcat
    14281 attcatttgg aagattttct acgatcgcat ctagcacatc ccctgtaccg attccatgga
    14341 cagatgagat aggcaatggt tcacccaaac cgagagcata gaaatcatag atatcatttc
    14401 tcatctcagg gttgtccacc ttgttgactg cgaggataac tggtttgtgg gtcttataaa
    14461 gcttacgagc tacgtattcg tctgcatcag taattccttc cttaccagac acgacaaaaa
    14521 cgataacatc tgcttcttcc atggcaattt ctgcctggtg cttgatttgt tccatgaaag
    14581 gagcatcgac atcatcaatt cctcctgtat caatcatgct aaaagaacga ttgagccact
    14641 cacccgttgc ataaatacgg tcacgtgtca ctccttcgac atcttctaca atggagattc
    14701 gctcaccagc gatccgatta aatagggttg atttcccaac attgggacgt cctacaatgg
    14761 caatagttgg tagggccata atttctcact ttctacaata atttcttctg ttcaagattt
    14821 tttctagttg agcttggttc agcttgacca aactgttctg ctaggcgctg actccagctt
    14881 gtggtcgcac gcgccccagc atagtcagcc tgaacacggt cataagcttg gattgcctca
    14941 gttgactgtt cttggtattc ttcctcaaag acaacattct ctagtggcag tcttggtttc
    15001 atatcatgat gttgatttgg cacacccagt gccatcccaa agacagaata ggtgtagtca
    15061 ggtaggttaa agagctctgc cacttcttca gacttgtatc gaaccaaacc gataatcaca
    15121 ccaccatagc ccaagctttc agctgccaac aaggcgtttt gtccagcaag agctgcatcg
    15181 accgaactaa tcaagagacc ttccacacct tggggttgga aggtgtcggt atgaagtcgg
    15241 gctccctttt ctgctcggtt caaatctccg acaaagagaa ggaaaacagc agactggcga
    15301 atggcttctt gaggtaccaa ttcatacaag gcatctttct tctcttgact tcgtaccaca
    15361 atcacagagt aggattggaa attcttccaa gatgatgcca tctgggctgc tgtcaaaatc
    15421 tcatttaagt ctacttgggg aatttcttgc tctttaaacc tgcgcactga agtatgagcc
    15481 ttcatcaatt taatggtttc tgtcatcgac ggtttactcc ttctaaacga gtctcctcag
    15541 ccaaataacg gatgcgttcc atgacccgtc tggcttccca ggtttcgtca tttccatgtt
    15601 tcactttcgc aaaatgcttc tccaaatctt caaagttgaa gttggatgtg aaaaaggtcg
    15661 gtaaattttc ctgcatccga tattggagaa tgacctgcag gatttcgtca cgcacccaaa
    15721 cggttgattg ctcggcgcca atatcatcta aaatcaggac ctcagacagc ttaatctcat
    15781 ccaccaaggt cttaacattg ccatcactga tagcattttt gacatcaatg acaaagctag
    15841 gatagtggag gagagtggat gatacaccac gtttttctga taaatcatga gctagggcag
    15901 ccaccatgaa acttttaccc acaccaaagt ctccatacaa gtaaagacct ttcaaattat
    15961 tagggtaatc gttaacaaat tctatcattc tttttagaac agttaagcgc tgaacatcat
    16021 cacgataaac atctaaaaaa ctgacatttt tcaggctaga tggaaaatta attaagttga
    16081 gacgtttctt gatagccgct tctttttcag ctgcgattag ttcaggagtt tcttcataag
    16141 aaacatctgc atagccatgg ttcatgacta atataggctt gtagcctttg gcaatataat
    16201 ctgtatctcc tcggaggaat ttatctctct cagtgatgta ttggttaaac ttggaaatac
    16261 tacggttcaa ctcgtcctga ttgagggatt cttgctggac aaaggccgca acatcaggat
    16321 ccttcatgat tttctgaact aaatcttgat agtgaaaacg acttggttga cgtttgagta
    16381 catctccgac actttccatc taatcacctc cgttatctaa ttttgctaat aattctaggg
    16441 tttggcgttc catctcttct aattcctcag cggatgacgt atttttatat tcaggattac
    16501 tccatttagg aatattggtt tttgctgggg cagtctgatt ctgtttttgt gtttttgctt
    16561 tctgttctcg ctcacggatg cgcaagactg ccttttctgc cgaatgaatc ttttgatagg
    16621 catagtcatt ggctaccttc atggcatatt tctcattgat atttgccgaa tcgaccttat
    16681 taaaggtcaa taaaagaatg atattgatga cttcgtccag caagcccaag ccagccatct
    16741 gttgcaagag ttctctttct gtttgggtaa tggttccctt gcgtgtttgc ttgatttctg
    16801 ccaagaactg cagggcagtt ttacttttgg cttctttgat aatggttgtt tccttaagac
    16861 taaagtcaga ggaaactggt ttttgagcaa ttttttcccg catgcgtttg gttgaaataa
    16921 cctgagaaac agctgttgac ttggccaatt gataggtttc aaaccaagtc catttcttct
    16981 cctcggcaat agcaaagagg tttaagacat cggactgctc atccgcaaaa cgaagtccat
    17041 ctcgagccat cagctggcga aaatggtcca agtcaaaatc gttggccact ttcttcttga
    17101 gaccaaggtc ttcttgactg cctagttctg ccaattctgg aaagacttga ttgagtgaga
    17161 caggtatttc ttcaccatca gcactttcaa ctttcaaatc ctccacagct acatcgccaa
    17221 tctttttctc taagagtctg cgataaacag gatgctccaa gaagtcttga ctagatagag
    17281 gagcatggag gactagctga taaacatccc ccttttgata gagggtcaag agattaaaag
    17341 cagataagat tttcaatgat tttatcagtc tatccatccc aaagttaaga tggttgagaa
    17401 tgcttgaaaa aagatattcc tttctaccat tatcccaaaa actgattgta taaagataaa
    17461 ggctcagtgc ctcctgaccg ataatcggga ggtagcactg taccagagat gaggtatctt
    17521 gcgacacccg attattcttt agataagaaa aacggtcaat tggcttcatt tatctttcct
    17581 ttttcttttt agaggactgg gtgatttgtt ggagcaagct ctctaactca ctgacatcct
    17641 taaaactacg atagacacta gcaaaacgta cataggtaat ctcgtccaat tcagccaact
    17701 cctccatgac gagtgaacca atgtcctcac tttgaatttc attttcattt cgaccacgga
    17761 gtttctgttc gatacgattg actaccatgt tgatttcatc acttgacaca ggacgtttct
    17821 gggctgagcg gataatccca ttaaagattt tatctctgga gaattgttcc cgtgtgccat
    17881 cttttttaac aaccactaag gttctttctt ctactcgttc gtaggttgta aaacggtgtt
    17941 ggcattcgtc gcactcacgt cttctacgaa tggtgttccc ttcttctgct tggcgactat
    18001 cgataacact tgacttggta gccccacatt ttggacaacg catcctttcc ctccttatcg
    18061 ttttcttttc attataccat tttttaagcg attcccaaaa caattcttct ttttgcttga
    18121 caagtttttt gttttgttgt attatttaat taagacaaaa gggtaaaaga aaggagacta
    18181 agatgtcctg gacatttgac aacaaaaaac ccatctattt acagattatg gagaaaatca
    18241 agcttcagat tgtttcccat acactggaac ccaatcaaca acttccaacc gtgagggagc
    18301 tagctagcga ggctggtgtc aatcccaata ccatccaaag agccttatca gaccttgaac
    18361 gagaaggatt tgtctacagc aagcgaacaa ctggacgatt tgtgactaag gataaggagc
    18421 taatcgctca gtcacgcaaa caattatcag aagaagaatt ggaacacttc gtttcctcca
    18481 tgacccattt tggctatgaa aaagaagaac taccaggcgt agtcagtgat tatattaaag
    18541 gagtttaagc ctatgtcatt actagcattt gaaaatgtat ccaaatcata tggagcaaca
    18601 ccagcccttg aaaatgtttc tcttgacatt ccagctggaa aaattgtcgg ccttcttggg
    18661 ccaaacggct caggaaaaac aaccctgatt aaactaatta atggcctctt acaaccagat
    18721 caaggacgtg tcctcatcaa cgacatggac ccaagcccag caaccaaggc cgttgtagct
    18781 tatttgcctg atacgaccta tctcaatgag caaatgaagg tcaaagaagc cctaacctac
    18841 ttcaagacct tctataaaga tttcaatctt gaacgcgccc atcatctact tgcagacctg
    18901 ggcattgatg aaaatagtcg tctcaagaaa ctatcaaaag gaaacaaaga aaaggttcaa
    18961 ctgattttgg ttatgagccg tgatgctcgt ctctatgttt tggatgaacc cattggtggg
    19021 gtggatccag cagcccgtgc ttatatcctc aataccatta tcaacaacta ctcaccaact
    19081 tctaccgttt tgatttctac ccacttgatt tctgatatcg agccaatctt ggatgaaatt
    19141 gtcttcctaa aagacggaaa agtcgtccgt caaggaaatg tagatgatat tcgctacgag
    19201 tcaggtgaat ccattgacca actcttccgt caggaattta aggcctaagc aaaggagatt
    19261 atttatgttt tggaatttag ttcactacga atttaaaaat gttaacaagt ggtatttagc
    19321 cctctacgca gccgtgctag tcctttctgc cctcatcgga atacagacac aaggctttaa
    19381 aaatctacct taccaagaaa gtcaggctac tatgctactt tttctagcta cagtctttgg
    19441 tggcttgatg cttacacttg cgatttcaac cattttcttg attattaaac gcttcaaagg
    19501 tagtgtctac gaccgacaag gctatctgac tttgaccttg ccagtttctg aacaccatat
    19561 catcacagcc aaactaatcg gtgcctttat ctggtcattg attagcaccg ctgtattggc
    19621 tctaagtgct gttattattc tggctttaac agctccagaa tggattcctc tttcttatgt
    19681 gattacattt gtagaaacac atctccctca gatctttctt acaggtatat ccttcctact
    19741 aaataccatt tcaggaatcc tctgcatcta cctggctatt tccattggac agcttttcaa
    19801 tgaataccgt acagcactcg ctgttgcagc ctacattggt atccaaatcg tcattggatt
    19861 tattgaactt ttcttcaatc ttagttccaa tttctatgtc aattcactgg taggactcaa
    19921 tgaccatttc tatatgggag caggtatagc cattgttaaa gaactcatat tcatagctat
    19981 cttttatctc ggaacctact acatcttgag aaataaggtt aatttgcttt aaataatttt
    20041 tacctagata tgtaacatac tcatagaaca aaagagacca ggcaaaaagt ctttaaaatt
    20101 agaaaacgca tagtatcaag tgttaaaaat ccttgatatt atgcgttttt tgtgagctga
    20161 cttatttcct ttcgctatat cgcaaaatga aataagaacg gaacgatggg attttggaat
    20221 tcaaatcaat ttataagaat gttttagaag taatattatc ctattccaga ttcagttcac
    20281 tatacaattg agttttcaag caacctgttt acataatgtg tacataatta ggttcgtgat
    20341 tccacccttt tcacctttaa aaacctcgct ttcgcaaggc tcttctattt ataagataag
    20401 gcacgtttaa aggttttcca aatccctaaa tcatccgttt gaagaacgag actagcatac
    20461 atgcgtccga taaatcctgt tgctaccacc gcaaaaatca ctgtaatagc aagtgaaatc
    20521 catgcttctg ctccccccgc atagccatta atcgttcgaa acggcataaa gaaggtcgaa
    20581 ataaagggaa tataagaacc aatcttcaag aggagattgt caccagctgc acctagagct
    20641 gtcactccaa aaaaaccacc cataatcaaa atcatcaaag gcgacaaggc tttccctgag
    20701 tcctcaggac gagaaaccat agatcctagg aaggctgcca agactacgta catgaaaaga
    20761 ctgatcaaaa taaagagcaa ggtattcagt gagatagcat ctcccaagtg atccaaaata
    20821 ccagactgag ccaagaatgg caaatcttta aagagcaaaa cggcagccag accacctaca
    20881 acatagatcc caatatgcgt taaaatcact agaaacagag ccatcatccg cgcatagaaa
    20941 tagtgacttg cccttatgct agaaaaaacg acttccataa ttttggtgcc tttttcactg
    21001 gcaacttcct gagctgttac acccgcatag gtaatcagaa tcatataaag aaagaatcct
    21061 aaggcacctg ctgcaattgt ttgaataaac tttttatttt ccttggcttc atcaatcttt
    21121 tctgtgaatt gaattgtctg cgctaagcgt ttttcctgct cttgagacaa ggaagcagtt
    21181 gaacgattaa gctgattttg cagttcattg agtgtacctg taacctcaaa tttaattcca
    21241 ttttcaagcg atgtttcgcc atgataaact gcctttagaa cactatcttc ttgatcaatg
    21301 gtcaaataac cttttaattt ttcttcttta attgcttctt tggcacttgc ttcgtcttta
    21361 tagtcgaagt taacaccatt tacattcttc agtccttctg ctacagatgg cactgttgtc
    21421 actactgcca ctttattatt tttagccata gaagaacctt ggatatgccc aattcctaca
    21481 gagattccta aaaagaggaa cggcgaaatc accataaaga agaaactcca tgactcgaca
    21541 tgtcgaagat aggtttcctt gattacaacc cacatatttc tcatacttcc actcctgatt
    21601 ctagtttaaa gatttcatcg atagttggcg cttgttggtc aaatgttgcg atatattgac
    21661 cttgagtcaa gattgggaag agttcccttc cagcgctctc atcctccaaa atcaatttcc
    21721 aactgccttg tttggtcaag ctcacctgtt tgacatgagg aagattttcc aattcttcct
    21781 tgcttcgttc acttgaaaca aagagacgcg ttttcccgta ttgattgcgg acatcctgaa
    21841 ctggtccgtg caagaccaca cggccatctc ggatcatcag aatatcgtca caaagttcct
    21901 caacattggt catgacatgg tcagaaaaga taatggttgc tccgcgctct ttttcctgaa
    21961 aaatgacttg tttgagcaat tctgtattaa ctgggtccaa tccactaaaa ggctcatcca
    22021 agataatcag gtctggttca tgaatcagag taataatgag ctgaatcttc tgctgatttc
    22081 cttttgacag actcttgatt ttatctgtca gctttccttt cacttccaac ctcttcatcc
    22141 attgagggag tttttctttg acttctttgg catccatgcc ttttagagtc gccaagtagc
    22201 gaacttgttc aagaactgtc aatttaggca tgagactgcg ttcttcaggc agataaccaa
    22261 tccgagcata ggtctcctga cgaatatcct gaccatccag accgatttct ccctgatatt
    22321 ctaggaattt caaaatacta tggaaaatcg ttgtttttcc agcaccattt tttccgacta
    22381 gtcccaaaat acgacctggt cgcgcttgaa agtcaatacc aaacaaaact tgcttggagc
    22441 caaaactttt ctctagactt cttacttcta gcatctttca cctccgaaat ttcttgcact
    22501 cattatactc ctttttgata gcctttacaa tgtttttgtc catttttaga agactattgc
    22561 tgtgtaaaat atggcctgga gcacttttat actcaatgaa aagcaaagag cgaactagga
    22621 agctagccgt aggctgctca aagtacagct ttgaggttgc agataaaact gacgaagtca
    22681 gctcaaaaca ctgttttgag gttgtggata gaactgacga agtcagtaac tatatctacg
    22741 gcaaggcgaa gctaacgtgg tttgaagaga ttttcgaaga gtattagtga taaatccatt
    22801 atacagtagc aaactcaatt tataccttcc gctcctcaac tgtctatttt taatcctgaa
    22861 ttgttatttg agtaactcct ttttcctcat aaagttttct tcctctaaaa cttctggaaa
    22921 aaagcgaata gtttcagaca acatttttat aagaaacaag ttcatctgtc atttcaagaa
    22981 ggagtaatcc tttatctact aatggacgga acggaattca accgcttgtc cgatatattt
    23041 tctaaggatt atatagtaaa atgaaataaa aacaggacaa atagatcggg acagtcaaat
    23101 cgatttctaa caatgtttta gaagtagatg tatactattc tagtttcaat ctgctatatc
    23161 tattatgcac accactatag gatctaataa aaatcacaac aagttcattc atagatggtt
    23221 acctcaggga actaagaaaa cgactacaaa ggaagtcgca ttcatcgaaa agtggattaa
    23281 caactatcct aaaaaatgct tgaactacaa gtcccccaga gaagacttct ggatgactaa
    23341 cttgaacttg aaatttagca ataattaatt caccatctaa ctatatttag taattatttc
    23401 agaactgatt aatattaaaa ttaactaaca attcaaagga ttcatactag ccataaatta
    23461 cgtccatcag agagagactc ttactacttt tagattttag tctttctagc ttcagaatac
    23521 atctaaactt tagggaaaat gactattcga aagcgcgaat gcctcaaaat tatctcagat
    23581 aagctattcg aaacttagaa tgcttttaaa tttatggaat tgcgattatt cgaaacctag
    23641 aatgcatata acctttagtt gacagaccta ttctaagtct cgaagggcta tttactttct
    23701 attccttatc aaaaaagact cattccccct ttctcctcca aaatatggta tagtagaaat
    23761 atactatcta tgaggagttt acatgtcaca ggataaacaa atgaaagctg tttctcccct
    23821 tctgcagcga gttatcaata tctcatcgat tgtcggtggg gttgggagtt tgattttctg
    23881 tatttgggct tatcaggctg ggattttaca atccaaggaa accctctctg cctttatcca
    23941 gcaggcaggc atctggggtc cacctctctt tatcttttta cagattttac agactgtcgt
    24001 ccctatcatt ccaggggcct tgacctcggt ggctggggtc tttatctacg ggcacatcat
    24061 cgggactatc tacaactata tcggcatcgt gattggctgt gccattatct tttatctagt
    24121 gcgcctatac ggagctgcct ttgtccagtc tgtcgtcagc aagcgcacct acgacaagta
    24181 catcggctgg ctagataagg gcaatcgttt tgaccgcttc tttattttta tgatgatttg
    24241 gcccattagc ccagctgact ttctctgtat gctggctgcc ctgaccaaga tgagtttcaa
    24301 gcgctacatg accatcatca ttctgaccaa accctttacc ctcgtggttt atacctacgg
    24361 tttgacctat attattgact ttttctggca aatgctttga cacgtaaaaa atccgtttgg
    24421 tttcccaagt ggatttttaa agcgtagatt aactatagct tgatactaaa tatactttgg
    24481 tatggaaatt atgcatattt ttcgatagtg aggcgaggac ttacctagcc tttccgccgt
    24541 gatagaaaca cctgaaatct aatggtttca ggtattcgga aactttgaga cactaggctc
    24601 aaagtttagg tatggaattt cgaagaaagt cgctaccgtc cgtaatcact taaggaaagg
    24661 ctcaaaaata ttgttttcaa ccacaaaatc cgtttggttt cccaagcgga ttttgtgctt
    24721 tattttgaaa cttcttttgc aagaacaaag ttcccaagtg tggcagaacc atttcctgcg
    24781 actgctggcg tcacgatata gtcacgcaca tctggtactg gtaggtaacc attaagaaga
    24841 gatgtaaatt tctcacggac acggtccagc atatgttgtt gagccatgac ccctccacca
    24901 aagacaatca cgtctgggcg gaaagtcact gtcgcattaa ccgcagcttg agcgatatag
    24961 taggcttgaa catcccaaac agggttgttg agttcaatat tttccccacg tacacctgta
    25021 cgagcttcca aacttggacc agctgcataa ccttctagac atcccttatg gaaaggacaa
    25081 acacccttaa actctttttc aatatccatt gggtgtctag caacataata atgacccatt
    25141 tcagggtgac ccacaccacc gataaactca ccacgttgga tgacgcctgc accgatacct
    25201 gtaccgattg tgtagtaaac caagttttcg atacgaccac cagcattgtt acgggcaacc
    25261 atttcaccgt aagcagagct gtttacgtct gttgtgaagt acattggcac gtttagggcg
    25321 cgacgaaggg caccaagcaa gtctacattt gcccagtttg gttttggagt cgtcgtgata
    25381 aagccataag tttttgagtt tttgtcaata tcaatcggcc caaatgaacc aactgcaaga
    25441 ccagcaaggt tatcgaattt tgagaagaac tcaatggttt tatcgattgt ttcgattgga
    25501 gttgttgttg gaaattgtgt tttttctaca acgttaaagt tttcatcacc gacagcacag
    25561 acaaactttg taccgcccgc ttccaagctt ccatataatt ttgtcatgat aaacctcttg
    25621 tttttatttt ctttattata gcatacttcg aaagtctaaa tgtctctatt ttttagattt
    25681 tcctctgtaa atcttactat ctaataaaaa cgaacaaaca tgtcatttgt tcgttttcac
    25741 attagagagg attgattaga ttttcacttc gatcacagca tcccccttcg aaactgaacc
    25801 tgttgcgact ggagctactg aagcgtagtc agctgtattt gtaacgataa ccattgttgt
    25861 atcatcaagt ccagctgcag cgattttgtt tgagtcaaat gttccaagaa catcgccagc
    25921 tttcacctta ttaccttgag caacttttgc ttcaaaaccg tcaccgttca tagatacagt
    25981 gtcaatacca acgtgaatca aaacttcagc accatttctt gttttcaaac caaaagcgtg
    26041 ccctgttgga aaggcaattg aaacttcagc atcagctagt gcatagacca cgccttgact
    26101 tggtttcaca gcgatacctt gtcccatagc tccacttgag aagactgggt cattgacatc
    26161 agcaagagcg acaacatcac cgacgatagg agttacaagt gtttcatttt gaagagctgc
    26221 tggcgcaact tcttcttttt cttcagccac ttcagcttgt tttgcagctg cagttgcgtc
    26281 tacttcatct tcgtaaccaa acatgtaagt aagagcaaaa ccaagggcaa atgatacagc
    26341 taccataaga aggtattgtg gaagttgtcc gttaccaaca taaagcattg taccagggat
    26401 gatggtgata ccattaccag taccagcaag tccaaggata gaagccaatc caccaccgat
    26461 tgcaccagca atcaatgaaa ggaagaatgg tttacggaag cgcaagttca ccccgaagat
    26521 agcaggctct gtaataccta ggaaggcaga aagagcagcc gggaaagcaa gtgttttcag
    26581 ttttggattt tttgttttaa caccaaccgc aacagtagca gcaccttgag ctgtcatagc
    26641 agctgtgatg atagcgttga atgggttagc atggtcagca gcaagtaatt gcacttcaag
    26701 caagttgaag atgtggtgca cacctgacac gacgatcaat tggtgaaccc caccaatcaa
    26761 gaaaccacca agaccaaatg gcatgctaag aatcgctttt gtagcaataa ggatgtagtt
    26821 ttcaacaacg tggaaaactg gtccaatgac aaagagtcca aggatagaca tgaccaaaag
    26881 tgtcacgaat ggtgttacca agaggtcaat gacatctgga acaaccttgc ggacagcttt
    26941 ttcaaattta gctccgacaa ccccgatgat gaaggctgga agaacggaac cttgcaaacc
    27001 aacaacaggg atgaaaccaa agaagttcat cgctgttact tcaccacctt gagcaactgc
    27061 ccaagcgttt ggaagtgagc cagagacaag catcatacca agaacgatac caacggcagg
    27121 atttccacca aatacacgga aggttgacca cacaaccaaa cctggcaaga tgatgaaggc
    27181 tgtatctgtc aagatttgtg tgtaagttgc aaagtcacct ggaagtggca tttcaagagc
    27241 gttgaaaaga ccacgcacac ccatgaagag acctgtcgct acgataactg ggatgattgg
    27301 aacgaaaaca tcaccgaaag tacggatagc acgttggaac cagttccctt gtttagcaac
    27361 ttctgctttc atgtcatcct tagatgatgt tggtaagcca agtacaacaa cttcatcgta
    27421 cattttgtta actgtacctg taccaaagat aatttggtat tgccctgagt taaagaaagc
    27481 accttgaact ttttccaagt tctcaatcac ttctttattg attttctctt catctttgac
    27541 catgacacgt agacgagtcg cacagtgggc aacactattg acattttcac gtccgcccaa
    27601 ggcatcgatg actttttttg caatttcctg attgttcatt tgcaaaaatc tccttatata
    27661 acattttgtt cttgtttgaa agcgatttta ttcgccctta cgactattat tttatcatgt
    27721 tttaaaaata tgtcaagcgt tttgcagaaa aaatattcta tccacttagt gggcaagttt
    27781 tagattgatt gtttttgact gtttcatcag gaattccttg aaaaataagt ttgaaacctt
    27841 ggttaaaaag tcttttattt cattatcttt cacattttcg taaaaatttg attgatttcc
    27901 tgtatttatt ttatgataat cgtttgacag tttttcctct tttttaacat aaaaggcttg
    27961 cattttttat cgaaaacagt tactattaaa agtgataaga tttttggagg aatgaatgga
    28021 atggacaact gagcgtcgtt acagacttta tcaagattgg acgcaagaag aaattcaaca
    28081 tataaaggaa aatatggcac aatctccatg gcatactcat taccatgttg agccaaaaac
    28141 aggacttctc aacgacccaa atggcttttc ttactttgat ggcaagtgga tcctctttta
    28201 ccagaatttt ccttttggtg cagcccacgg tttgaaatct tgggcacagc tagaaagtga
    28261 tgatttggtt cactttaaag aaactggaat caaagtttta ccagatactc cattagatag
    28321 ccacggtgcc tactctggtt ctgccatgca atttggcgat aacttattcc tattttatac
    28381 aggaaatgtt cgcgatgaaa actggatccg tcacccatac cagatcggtg ctttgatgga
    28441 caaggagggt aagattacaa agattgacaa gatcttgatt gaccagccag cagactctac
    28501 tgaccacttc cgcgatccac aaatttttaa ctttaaaggt caatactatg ctgtcgtcgg
    28561 tggacaggac ttggagaaaa aaggcttcgt ccgtctctac aaggctgtca ataacgacta
    28621 cacaaactgg caagcagttg gcgaccttga ctttgctaac gaccgtactg cctacatgat
    28681 ggaatgtcct aatctggtct ttgtagagga acatcctgtc cttctctact gtccacaagg
    28741 attggataag aaagttctag actacgataa tatctttcca aatatgtata agattggggc
    28801 ttcctttgac cctaaaaatg ccaaaatggt agatgtgtct caacttcaaa acatggatta
    28861 cggtttcgaa gcctatgcaa ctcaagcctt caacgctcct gatgggcgtg ctctagcagt
    28921 tagctggctt ggtttgccag atgtttctta cccatctgac cgttttgacc accaaggaac
    28981 cttctctttg gtcaaggaac tcactatcaa agacgacaag ctctaccagt atccagtcgc
    29041 tgctattaag gaccttcgtg cttctgaaga agccttctca aaccgttccc aaaccaagaa
    29101 cacttacgaa cttgaactca acttggaagc taatagccag agcgagattg tcttacttgc
    29161 tgataaagaa ggtaagggac tttcaatcaa ctttgacctt gtaaacggtc aagtgacagt
    29221 ggatcgtagc caggctggag aacagtatgc ccaagaattt gggacaactc gttcttgccc
    29281 tatcgagaat caggctacta ctgctacaat cttcatcgat aactctgtct ttgaaatttt
    29341 catcaataaa ggagaaaaag tattttctgg tcgtgtcttc ccacatgcgg accaaaatgg
    29401 tatcctgatc aaatctggaa acccaactgg aacttactat gaattagatt atggtcgcaa
    29461 aactaactga tgtcgccaaa cttgcaggcg tcagtcctac taccgtttct cgggttatca
    29521 ataaaaaagg atatctatct gagaaaacca tccaaaaagt caatgaagcc atgagagaat
    29581 taggctataa acccaacaac ctggctcgta gtctgcaagg aaaatcagct aagttaatcg
    29641 gcttgatttt ccccaatatt tccaatgttt tctatgcaga attgattgat aaattggaac
    29701 accaactctt caaaaatggt tacaagacca tcatctgcaa cagtgaacat gattctgaga
    29761 aggaacgcga atacatcgaa atgttggaag ccaatcaggt agacggcatc atttctggta
    29821 gtcacaacct aggaatcgaa gactacaatc gtgtgacagc gccgattatt tcctttgacc
    29881 gaaacctatc gccagacatc cctgttgtct cctctgacaa ctatgctggt ggggttcttg
    29941 ctgcccaaac cttggtcaag acaggtgccc agtctatcat catgattaca gggaatgaca
    30001 attccaattc gccaaccgaa ctgcgccacg ctggttttgc atccgtactc ccaaaagctc
    30061 ctattatcaa tgtttccagt gacttttctc ccgtcagaaa agaaatggaa atcaagaata
    30121 tcttgacccg ggaaaaacca gatgccattt ttgcttcgga tgatttgaca gctattctgg
    30181 tcattaaaat cgctcaagaa ttgggcattt ctgtcccaaa agagctcaag gtcatcggct
    30241 atgatgggac ctactttatc gaaaattact accctcaatt ggctactatc aagcaacctt
    30301 tggaagagat tgcttgtctc actattgatc ttctcttgca aaagattgaa ggcaaggaag
    30361 tcgccacaac tggttacttc ttaccagtta cgctattacc aggaaaaagt atttaaacac
    30421 aagaaaactc agaccgattc gtctgagttt ttatgatctt aaattttcga gatagcgctg
    30481 ggctgtctct aggttaaagg ttttatctga gatgaggcgc tctactaggg gagcaacttc
    30541 agattcacta gccccagcta ggagagctag ggatttggcc tgtagtttca tgtggccttg
    30601 ctggatgccc gtacttacca aggctttgag ggctgcaaaa ttttgagcaa gaccgatgga
    30661 cacgataatc tgggctaatt ctctggcaga aggatttcct agtagatcat gactgagagc
    30721 tacacgtggg ttgaggccga tagagccacc cttagtcgct acaggcatgg gcagggtcat
    30781 ctcaccgacc aattcttctc tttcaaggtc cagcgtccag cagctaagac cttgatagcg
    30841 tccatctcga ctggcaaagg catgggcccc agcttcgatg gcacgccagt cattaccagt
    30901 ggcaatcaaa atcgcatcaa taccattaaa aattccttta ttatgagtag cagctcggta
    30961 aggatcagcc tgcgcaaact gactagccaa cgcaattttc tccgcaatct ctcgtccttg
    31021 atccttttgg cggctcaagt agcgaaaggc gatgcgacag cttgcagtca ccagagaatc
    31081 agtcgcgtag ttggacagga ttcccatgag actctgtccc tgactgagtt cttctaagac
    31141 tggtttcaag gcttccagca tggtgttgag catattggca cccatggctt cctgggtatc
    31201 gacatgaata taaacaacga gaaagtctgg ttcgcctttt atctgctcga catgcagatc
    31261 acgcgcccca cccccacgtt taacgataga aggataggct tgattggcaa gctccaagag
    31321 ctccgctttc ttgctggcaa tcttctcttg cgctagttta ggattagcaa cttgataaag
    31381 ggctacctgc ccaatcatct ggcgctgatg gacttgtgca gtaaaaccac ctgcacgctt
    31441 gatgattttg ctggcatagc tggccgccgc aaccacagag ggttcttctg tcacataggg
    31501 aacggtgtat tcctgaccgt tgacaagtac ctccggaacc agtgaataag gcagagaaaa
    31561 agttcccact acattctcac tcagctggtc tgccacagtc acgctcatct gttcatcctt
    31621 ctccagacta gcttgtctct caggactaag gagcgcctga gcttttaaca gctcgaggcg
    31681 ctcttggtat gattttttag aaaatccatt ccaacttatc ttcattattt ttcaaccttg
    31741 ctataacggc gttggtggtc gagaatttca accaaggcaa aatcttgatt ttcatagcca
    31801 gcaaactggg cagagtttgt ttcatccaag tttacttcct caaaaaagac cttttcatag
    31861 tctgcaacgg atagggcagt tcgttggttg agcttgttca aacggtcttt atccaaataa
    31921 gcttcatatc cttcaaccaa ttcaccactg aagaactcag ccacagctcc acttccgtaa
    31981 ctataaaggg cgattttatc cccagctttc aagctatctg tattttccaa gagagacaaa
    32041 agtccaagga aaagtgaacc tgtgtagata ttccccacct tttgactgta gagaatagac
    32101 tggtcaaaat gcttttgtaa gaggtctttt ttctcttgag gcaggctctt atccatgatt
    32161 tttttcaagc cttttagcgc taatttagga taaggcaagt ggaaacaaac agccgcaaaa
    32221 tcatccaaag taagctggta gcgtttttga tattcaagcc aagtcgtttt caaactatcc
    32281 aagtattgtt gggtagaata gacaccattt acataaggag ttgtcgagta atttggtcgc
    32341 cagaaatcca tgatgtcacg ggtctgagct acattgtcat tattaaaggc catcatgcgt
    32401 ggattttgtg taatcaacat agccacactt ccagcacctt gagttggttc tcccggagtt
    32461 tcaataccat atttggcaat atcactggca atgaccaaga ccttggactc cggagaattt
    32521 tccacatgca atttggcata atggagggca gctgtcgccc catagcaggc ttctttaatc
    32581 tcgaaactac gagcaaaggg ctggatgccc agcaagccat gcacaaagac ggccgcagcc
    32641 ttactctggt caattcctga ctcggtagcc acaatgacca tgtcaacttc ttgtctttct
    32701 tgctcagtta aaatagagtc actagcactg gccgccaagg tcacgatgtc ctcagttagg
    32761 ggcgcaatac tcaattcctt gagtaagagt cctttactta atttttcagg gtcaattccc
    32821 ctcgcttctg ctaagtcttg taatttcaag acatattgac tggtcgcaaa accaatctta
    32881 tcaataccga ttgtcatatt tacctctgtt ttatcattca tgtaaaaaat cgttctatac
    32941 tattttatca caaatggcag taaaagagag aaaaaagact tgattcacca aatcaagcct
    33001 cttattggtc atcattttaa agaatgatta gttgctagag agttcaccga tataagtagc
    33061 tttataagct ccattcacag ttatcagctc ctggaggatc aaatttcctg agtaagtcct
    33121 tcccatctca tctacaaatt tttgataaaa ctgactggtc ggaatttctc tgacatcctt
    33181 atcaaatgtc ttgtcaagtg ttttactaac cttctcagca atcaattgat gctcttgcca
    33241 tccactttga aactctgagc cccaactaga aaccatgact gggataaaca acaaggtcag
    33301 tagacttaca gacaataagg aaaata
//
LOCUS       DAVHLA010000022        32232 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVHLA010000022 DAVHLA010000000
VERSION     DAVHLA010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32232
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.022"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(228..1316)
                     /locus_tag="VVO77_001154"
     CDS             complement(228..1316)
                     /locus_tag="VVO77_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEU5693172.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNCPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTIKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            complement(1334..2002)
                     /locus_tag="VVO77_001155"
     CDS             complement(1334..2002)
                     /locus_tag="VVO77_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEU5693173.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHKIRRQAGDDIFIKVPVTPAGLRAIKALK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVIQN
                     SRSI"
     gene            complement(2021..4459)
                     /locus_tag="VVO77_001156"
     CDS             complement(2021..4459)
                     /locus_tag="VVO77_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEU5693174.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMTIYIEEESMIGGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKAALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPVTTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            complement(4610..5908)
                     /locus_tag="VVO77_001157"
     CDS             complement(4610..5908)
                     /locus_tag="VVO77_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU5693175.1"
                     /translation="MAKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLLSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVITQLVILAMSTLVYFPFFKVQDRLAYQNEIKQS"
     gene            complement(5925..6233)
                     /locus_tag="VVO77_001158"
     CDS             complement(5925..6233)
                     /locus_tag="VVO77_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU5693176.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQASGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            complement(6279..6599)
                     /locus_tag="VVO77_001159"
     CDS             complement(6279..6599)
                     /locus_tag="VVO77_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU5693177.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            complement(6794..7774)
                     /locus_tag="VVO77_001160"
     CDS             complement(6794..7774)
                     /locus_tag="VVO77_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEU5693178.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            complement(7787..8533)
                     /locus_tag="VVO77_001161"
     CDS             complement(7787..8533)
                     /locus_tag="VVO77_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU5693179.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            8655..9431
                     /locus_tag="VVO77_001162"
     CDS             8655..9431
                     /locus_tag="VVO77_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEU5693180.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGVNALHPEDLIDYQKVFLNHHINCYF"
     gene            9506..9703
                     /locus_tag="VVO77_001163"
     CDS             9506..9703
                     /locus_tag="VVO77_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEU5693181.1"
                     /translation="MTLNEYILQYRLKQAIDKMAESPNSPLSAISDQVGFSDYKYFAK
                     VFKKYLHISPKKLKSLGRIVK"
     gene            9921..10517
                     /locus_tag="VVO77_001164"
                     /pseudo
     CDS             9921..10517
                     /locus_tag="VVO77_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466308.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            10593..11042
                     /locus_tag="VVO77_001165"
     CDS             10593..11042
                     /locus_tag="VVO77_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000337416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU5693182.1"
                     /translation="MCTILVSIYYKIGLSSSGVYKAVADGEMTVGLSYEDPAVKLLND
                     GANIKVVYPKEGTVFLPASAAIVKKSKNMENAKKFIDFIISQEVQDTLGTTTTNRPVR
                     KNAKTSENMKPIDKIKTLTEDYDYVIKNKSDIVKKYNEVFTDIQSKQ"
     gene            11055..12146
                     /locus_tag="VVO77_001166"
     CDS             11055..12146
                     /locus_tag="VVO77_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5693183.1"
                     /translation="MSEIEIINAKKIYHDVSVIENLNITIPKGSLFTLLGASGCGKTT
                     LLRMIAGFNSIKDGEFYFDDTKINNMEPSKRNIGMVFQNYAIFPHLTVRDNVAFGLMQ
                     KKVPKEELIQQTNKYLELMQIAQYADRKPDKLSGGQQQRVTLACALAVNLSVLLMDEP
                     LSNLEAKLRLDMRQAIREIQHEVGITTVYVTHDQEEAMAISDQIAVMKDGVIQQIGRP
                     KELYHKPANEFVATFIGRTNIIPANLEKRSDGAYIVFSDGYALRMLALDQVEEQAIHV
                     SIRPEEFIKDESGDIEGTISDSVYLGLNTEYFIETGFASKIQVSEESTFEEDLQKGNR
                     IRLRINTQKLNIFSADGSQNLIKGVNHGT"
     gene            12136..13781
                     /locus_tag="VVO77_001167"
                     /pseudo
     CDS             12136..13781
                     /locus_tag="VVO77_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(13884..14576)
                     /locus_tag="VVO77_001168"
     CDS             complement(13884..14576)
                     /locus_tag="VVO77_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU5693184.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(14820..16157)
                     /locus_tag="VVO77_001169"
     CDS             complement(14820..16157)
                     /locus_tag="VVO77_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEU5693185.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPNINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            complement(16167..16433)
                     /locus_tag="VVO77_001170"
     CDS             complement(16167..16433)
                     /locus_tag="VVO77_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEU5693186.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            complement(16698..17084)
                     /gene="rplQ"
                     /locus_tag="VVO77_001171"
     CDS             complement(16698..17084)
                     /gene="rplQ"
                     /locus_tag="VVO77_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEU5693187.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            complement(17096..18031)
                     /locus_tag="VVO77_001172"
     CDS             complement(17096..18031)
                     /locus_tag="VVO77_001172"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEU5693188.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            complement(18074..18457)
                     /gene="rpsK"
                     /locus_tag="VVO77_001173"
     CDS             complement(18074..18457)
                     /gene="rpsK"
                     /locus_tag="VVO77_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEU5693189.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            complement(18475..18840)
                     /gene="rpsM"
                     /locus_tag="VVO77_001174"
     CDS             complement(18475..18840)
                     /gene="rpsM"
                     /locus_tag="VVO77_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEU5693190.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            complement(18858..18974)
                     /gene="rpmJ"
                     /locus_tag="VVO77_001175"
     CDS             complement(18858..18974)
                     /gene="rpmJ"
                     /locus_tag="VVO77_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEU5693191.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            complement(18999..19217)
                     /gene="infA"
                     /locus_tag="VVO77_001176"
     CDS             complement(18999..19217)
                     /gene="infA"
                     /locus_tag="VVO77_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEU5693192.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            complement(19334..19972)
                     /locus_tag="VVO77_001177"
     CDS             complement(19334..19972)
                     /locus_tag="VVO77_001177"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEU5693193.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGIINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            complement(20123..21433)
                     /gene="secY"
                     /locus_tag="VVO77_001178"
     CDS             complement(20123..21433)
                     /gene="secY"
                     /locus_tag="VVO77_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEU5693194.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            complement(21446..21886)
                     /gene="rplO"
                     /locus_tag="VVO77_001179"
     CDS             complement(21446..21886)
                     /gene="rplO"
                     /locus_tag="VVO77_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEU5693195.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            complement(22031..22255)
                     /gene="rpmD"
                     /locus_tag="VVO77_001180"
     CDS             complement(22031..22255)
                     /gene="rpmD"
                     /locus_tag="VVO77_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEU5693196.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            complement(22227..22721)
                     /gene="rpsE"
                     /locus_tag="VVO77_001181"
     CDS             complement(22227..22721)
                     /gene="rpsE"
                     /locus_tag="VVO77_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEU5693197.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            complement(22739..23095)
                     /gene="rplR"
                     /locus_tag="VVO77_001182"
     CDS             complement(22739..23095)
                     /gene="rplR"
                     /locus_tag="VVO77_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEU5693198.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            complement(23179..23715)
                     /gene="rplF"
                     /locus_tag="VVO77_001183"
     CDS             complement(23179..23715)
                     /gene="rplF"
                     /locus_tag="VVO77_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEU5693199.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            complement(23907..24305)
                     /gene="rpsH"
                     /locus_tag="VVO77_001184"
     CDS             complement(23907..24305)
                     /gene="rpsH"
                     /locus_tag="VVO77_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEU5693200.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            complement(24590..24859)
                     /gene="rpsN"
                     /locus_tag="VVO77_001185"
     CDS             complement(24590..24859)
                     /gene="rpsN"
                     /locus_tag="VVO77_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEU5693201.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            complement(24877..25419)
                     /gene="rplE"
                     /locus_tag="VVO77_001186"
     CDS             complement(24877..25419)
                     /gene="rplE"
                     /locus_tag="VVO77_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEU5693202.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            complement(25443..25748)
                     /gene="rplX"
                     /locus_tag="VVO77_001187"
     CDS             complement(25443..25748)
                     /gene="rplX"
                     /locus_tag="VVO77_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEU5693203.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            complement(25826..26194)
                     /gene="rplN"
                     /locus_tag="VVO77_001188"
     CDS             complement(25826..26194)
                     /gene="rplN"
                     /locus_tag="VVO77_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEU5693204.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            complement(26220..26480)
                     /gene="rpsQ"
                     /locus_tag="VVO77_001189"
     CDS             complement(26220..26480)
                     /gene="rpsQ"
                     /locus_tag="VVO77_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEU5693205.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            complement(26505..26711)
                     /locus_tag="VVO77_001190"
     CDS             complement(26505..26711)
                     /locus_tag="VVO77_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEU5693206.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            complement(26721..27134)
                     /gene="rplP"
                     /locus_tag="VVO77_001191"
     CDS             complement(26721..27134)
                     /gene="rplP"
                     /locus_tag="VVO77_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEU5693207.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            complement(27138..27791)
                     /gene="rpsC"
                     /locus_tag="VVO77_001192"
     CDS             complement(27138..27791)
                     /gene="rpsC"
                     /locus_tag="VVO77_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEU5693208.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            complement(27804..28148)
                     /gene="rplV"
                     /locus_tag="VVO77_001193"
     CDS             complement(27804..28148)
                     /gene="rplV"
                     /locus_tag="VVO77_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEU5693209.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            complement(28160..28441)
                     /gene="rpsS"
                     /locus_tag="VVO77_001194"
     CDS             complement(28160..28441)
                     /gene="rpsS"
                     /locus_tag="VVO77_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEU5693210.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            complement(28545..29378)
                     /gene="rplB"
                     /locus_tag="VVO77_001195"
     CDS             complement(28545..29378)
                     /gene="rplB"
                     /locus_tag="VVO77_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEU5693211.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            complement(29396..29692)
                     /locus_tag="VVO77_001196"
     CDS             complement(29396..29692)
                     /locus_tag="VVO77_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEU5693212.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            complement(29692..30315)
                     /gene="rplD"
                     /locus_tag="VVO77_001197"
     CDS             complement(29692..30315)
                     /gene="rplD"
                     /locus_tag="VVO77_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEU5693213.1"
                     /translation="MANVTLFDQTGKEAGQVVLNDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKLVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            complement(30340..30966)
                     /gene="rplC"
                     /locus_tag="VVO77_001198"
     CDS             complement(30340..30966)
                     /gene="rplC"
                     /locus_tag="VVO77_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEU5693214.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            complement(31183..31491)
                     /gene="rpsJ"
                     /locus_tag="VVO77_001199"
     CDS             complement(31183..31491)
                     /gene="rpsJ"
                     /locus_tag="VVO77_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEU5693215.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            complement(31757..>32232)
                     /locus_tag="VVO77_001200"
     CDS             complement(31757..>32232)
                     /locus_tag="VVO77_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEU5693216.1"
                     /translation="NLLETDPYITSGRYLVVPKDAPNQKVTASLPVAHELESLQRDIL
                     ALQAGMDVLTIEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELK
                     RRLARDTTVRNRYASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
BASE COUNT         9639 a         6859 c         5505 g        10229 t
ORIGIN      
        1 taattaatgt attcacaata aatagccgac aacctatgtc gctttttgat ttatgaagaa
       61 cgtatagtag actgaatctg aaatagtacg aaacaattgc taaaacactt atagaaatta
      121 attttacttt cccaatcgat ttgttctcat cttatttcaa tctgctatag aattcaatac
      181 gaggatcaat aaaagactac catttggaaa acagtagtcc ttattgttta ttttgaattt
      241 acataggcat ctacagcgat aatagcttga gcaacatctg aaggcgaaat cttaaacggc
      301 atctgatgaa ttgtctcacc ctccatagtt gcttgtttac caacttttat taaatcatca
      361 tatccaactt gatccaaatg catttctttt atagttgttg gcataccaat ttttttgtaa
      421 aactcaatat acttatcaag ttcttcttta ggtctatttt ccaataatag ttgtactaaa
      481 gttccataag ctactttttc accatgtgtt aaatgatgaa tgtcacctgt caatgcagta
      541 aaaccattat gaattgcatg cgccgcagct aatcctccac tttcaaaacc tagaccactc
      601 aataaagtat tagcttcaac aatattttct aatgctggtg tcaccacttt agcttcacaa
      661 gctgccatag cctgtaaacc atctgcaaac agcgtttctt cacatttctt cgcaattgca
      721 actccagcca atgtttgctg ttgtcccaac atagtttttc catttgcctg cataaccgca
      781 cgcgcctcaa cccaagttgc taaaccatct gcaataccag acgctaataa acgcttaggg
      841 gcttgtgaaa taacttttgt atcaaccaaa actaaatctg gatttttaga ataaaataga
      901 taatgatcaa atgcaccttc atctgtataa ataacagata aagcagatac aggtgcgtcg
      961 gtcgatgcaa ttgttggagc aataataaca ggcttttcaa tcaaatctgc aatagctttt
     1021 gcgctatcaa tcgtctttcc cccaccaaga ccgataatac tatcacaatt ttctttctca
     1081 gccaaggcaa caactcgatt gatttcattg tcagaagctt caccattaaa tagcgccaga
     1141 acaatatgga aaccatacct atgtagataa tcttcaaatc gttttccaac aatatcataa
     1201 accaactgat cgcataatag aatagggcaa tttcccaaat ccaaaattga tttggcattt
     1261 tcaaacaagg cattttcccc ctgaatatat ctagaaggac tagcaaaaat tctcatatgt
     1321 atttcctctc tatctaaatg gaacgactat tttgaataac aaaccaatcg tcagaaaaat
     1381 catcaaccgc cttttggata gatggcatgg cgaaagctga ttcaaaaaca tccgctcctg
     1441 ctgtaacagc atgcgcacct gcagctaaag cattatttac ttgtgctaca tttttaaagg
     1501 atgcagctaa aatcttacta ggagagttct gtctatcaat agcaagagct aattgacgaa
     1561 tgacagaatt tgaatcaatg ttcagatttt ccattctatt ataatatgga gctaggtaat
     1621 ccgctcctgc ttcgatagct aataatccct gaataactgt ataaatagct gttgcagtga
     1681 tatggtagcc ctcttttttt agcgccttta ttgcacgtaa tccagctgga gtaacaggta
     1741 ctttgataaa tatatcatct cctgcttgtc ttcgaatttt atgagcatcc tttaagatgc
     1801 cttcaaaatc ttgagaaatc acctgaacat gaatagaggg tgtagagcca atcaattctc
     1861 ttacatcttt gattcgttca aaaaaattaa tagaaccctc tctttttgca atagtgggat
     1921 ttgaagttac cccagctagc ggcaaaattt cagaccactt tttaatctca tctaaattta
     1981 atgtgtcaag cataaattcc ataaaaagaa cctctttatt ttacaaagta tgctcagtac
     2041 gtcctataat gtcatcttgg gttgccttag aaagaacatt gaagaatgca gagtatcctg
     2101 caacacgaac aattaagtct ctgtgttttt caggatgttt ctgagcgtca atcagcgtct
     2161 ctctggaaac aacattgtat tgaatatggt acccatgtaa acgattaaag aatgttcgta
     2221 acaaagcaat tagttttaat ttatcttctt ctttggctaa cgtttgagga tttactttct
     2281 gatttaagag aaccccacct acgatttcat ctgttggtaa ttttgaaaca gattttaaaa
     2341 cagatgtagg gccgtgttga tccatattat gtgatggtga acaaccctct gctaacggtg
     2401 tacccgcgtt gcgtccatct ggagttgcta atgttccacg tccctgccct acgttggctg
     2461 agatagaaga tgttcctgaa taacgaattc ctccaattgg acctcttcca taacgtgtat
     2521 taggatattt agcaatttca tcaacataaa tgtcataagc agcagtaacc aatttgtcag
     2581 cataatcatc atcattacca tacttaggtg catcatgaat caacatttct tgaatgacct
     2641 taccttcttc tccggcataa tctgtttcca gtgcatgcca aagctgactt gggcttatac
     2701 gttcttcctc aaacaccaat tttttaattg cagctaatga atccgacaaa tttgcaattc
     2761 caacttgcaa tcctgatata taatcatata ctgctccacc ttctttaagg tgttttccac
     2821 gaccaataca atcatcagtc aatgctgaac atagaatatc aggaacttct cgttccaatg
     2881 ataaatcaat agaattttca acaataacac tcattcgtgt caaatatctt agtgttttat
     2941 cccaagcatt ttctaattca gaaaagttct tcatatcctt aaaatgacca aagcttggtg
     3001 caaaccgttt acccgaagcc ggatcaattc catcattcat cgtgataagt agaaccttag
     3061 ggaagttcat ataactcata cctgtgcaac gatagcccca tttccctgga actgccgttt
     3121 caacacatcc aatggcactg taatcataag catcatcttc caatactcct tttgcaataa
     3181 aagaaggaat aataatctca tcattattaa atgcaggcat accaaaacca agtttcatca
     3241 cttcaataca ctcattcatg aaacgagcat ctaaacctgc atggtaacgt acagttagat
     3301 taggttgcgg tagatgggtt tgtgcaactg attttaatac caaataagat aatgggttaa
     3361 cagcatcctt cttatctcga gtctgtccac caattgtaac attttgatat aaaggacttc
     3421 ctgctgaaga aaatgtatgt gattgactgc gaaccttatt aattgtaatt gtcttaatcc
     3481 aaagatttgt cagacgttca acaatgctat cttctgtttc tttaccactt tctaaatcag
     3541 ccttcatata tggatacata tattgatcaa aacggccata tgaaagagag tggccattag
     3601 attcaatttg taaaatacat tgaataaacc aaactgattg aatagcttct gcaaaagtag
     3661 ttaccggttc atatgggact ctagagcaaa tatctgcaat ctcaagtaat tctttcttac
     3721 gtttaggatt tgcattttcg gctaaacttt tagcaagagc aacaaagcgc tttgcatata
     3781 ctttaatagc atcgattacg ataaatatag agtcgtaaaa atgatattta tcaatacttg
     3841 ctggatctgt taaatctaga gctgcttttg ctttacgagc ccgctcttca aaacctctta
     3901 agccaaattg caaaagtttc tgatagttaa ctgctaggtg agcatctcca gaattcatct
     3961 taccttccat accgaagaat cctgtttcca tataaacaga cacttcttca ggtaataagg
     4021 caccagctct agcacgtaaa ttattatttt cccaaaacgg agcaatactt ctaagttgtt
     4081 cttttgtttc ttctgtaata tagaaaacat ctccatcacg cttttcaaaa agatccaact
     4141 cattgagaac aaattctagc gtatattccg gaaaaatagg agcatcttta ttggaagaag
     4201 cttgatttcc cccaatcata gattcttctt caatatagat agtcatattt tccaaaattt
     4261 ctttcagcat atatgcacgt tttaggacat taggttgttc cttgtatcgt tcataggcgc
     4321 gtgttgctag aactgctctc tcagcatcaa tataaggttt tttatttaaa acatcttctc
     4381 gatatttgtt catcctttca gtaaggctgc caaaatattc tgtcttgatt gttgttcttg
     4441 ctacttctgt atttaccatc gtaaccacct ttctttcgaa aatattttta tttctttcga
     4501 aaatataata ccgattttta tagaaatttt caagctttta actagaaaaa ttttaactct
     4561 ctaattttta gcacaaatgt gtgagtttaa cagtaacaca caaatacctc taagattgtt
     4621 tgatttcatt ttggtaagct aaacgatcct gtactttaaa gaatggaaaa taaaccaatg
     4681 tagacatcgc taatatcacc agctgagtaa taactccttg ccatccaccc accaaaaatc
     4741 ctgataaaat agctggtgta ctccaaggca atgttacccc tgagaatggc tgcatgaaac
     4801 ctgttgcaat agctccatat actatcacag ctgcaagtac aggaacaaga atgaaaggta
     4861 caaacataac tggattcatg acaatcggaa atccaaatac aactggctca tttacgttaa
     4921 atattgctgg aaaagcggca acttttccta aggcttggta ttgttttgat tttgctgcaa
     4981 aaagcatggc aactacaaga ccaaacgtaa tccctgaacc tgatagaatt aaaaatgaat
     5041 ctaaaaattg ttgagtaaca atatgtgcac cattttctaa tgatagatta ccagaggcta
     5101 acatagcttt attagcatca agattagata aaagcagagc tgtcactact ccatttacta
     5161 ccgattgtcc atgaacacca aaccaccaca aaaatgatat aaagaatgca attccaatag
     5221 caccatacaa agatccagtt aaaccttgca atggaacttg aatagcagaa taaatcattt
     5281 ctatgaatgt tccgccatta gtcaatgact tcgctaaaat atatacaatc atagaaagta
     5341 agaaaattac aaatgctgga atcattgctt caaactgttt ggcaatagct tgtggaactt
     5401 gttctggcat cttaataaca atttttctct ttataaagaa ggtataaata cttcctacta
     5461 ccaaacctat aatgatagca ccgataattc cttgacctcc aaaccaaact ttactaatag
     5521 catccccaat tgcctcacct tgtttaggga tataagatga tcttagcaaa ataaagaatg
     5581 cagatacaga tagaactcca gctggtaaag cctctactcc gctattctta gcataagaat
     5641 aggcaattga aaaacaagaa attagaccca taatagcaaa agttcctgaa tatacttgca
     5701 taaacggctc tgtccaatta gctccaaaaa cactagcaat gctcttattt aatccttcga
     5761 acggcaattg tcccataatc aagaataaac taccaactac tgtcaatggc aaaattgcta
     5821 acatcccatc ttttagagct ataatgccac gcatattcac aaacttcatc atcggtgcaa
     5881 tgattttctg aacatccatc tttgccataa taaatctcct tttcttaccc actaatcaaa
     5941 gatagggcca aatctaatac ttttttccca tctaacatac catagtccat catcggaata
     6001 acagctatcg gaacatcaca cttatcacaa atttcttttg atttatctaa tgtataagca
     6061 acttgtggac ccaatagtgc aacatctata tttggcgcat aatccgctaa tttagactga
     6121 gaaaacgcct ctatttctgc ctcaactcca ctagcttgcg ctgcaatttt catattattt
     6181 acaagcatac cagtagaaaa acctgctgca caaaacaaac caatcttcac cattatgttt
     6241 tcctcctcta tgttaataac aatgataata ctctagtatt attttttatg aagttctttt
     6301 ctcaaactaa taatttcttt gattaaatta atctccgtca tactagtcat gagatgatct
     6361 tgtgaatgaa caaagagagc tgtaatttct gtctttgtac cagacgcttc ctgtgccaag
     6421 aattttgttt gtagattatg agcttctaat aaggctgcat cagctaactg gatttcttct
     6481 tcacatcgtt cacatgtacc attttttatg taatctaacg ctttataaat atgttgtttc
     6541 gcatcgccag catataaaat taaacccatg ataatttgat ctggaacaat aatttccata
     6601 aattcctcct catttcacta tgtaaaaagc ttttttcatt tgaaatttta aaattttctt
     6661 ttgtaactat agaatacaac tacataataa agttgtcaat ccaaaaacaa cagataaact
     6721 atttttgttt atataagcac aaatgtgcaa tcaactaaaa agaaaaacga taaactgaat
     6781 cagtctatca ttttcactca cctagaatct ctctaaaagt caaatcccca tcttcttcca
     6841 aaacttttaa aattgtattt ttgtctgtaa tcaaatgatt tactaaatta gcacgcaaga
     6901 cagaaagaat cgaagatact ttcgtatcac cgtaagcaac agctaaactt tgaggaatat
     6961 tttttaaatc ttccaaagag attgctatcg ttctttcctg taagttttca tagacttctt
     7021 taccttttga atcaaaaaat cgacaacaaa tttctcctac agttttaact ttggtcaatt
     7081 ctttaaagtc atcctctgta agcatgtcta accattgatg ttttccttta ttgctaaaat
     7141 caccaattcc gactacagct atatctaaat ctttccaact atttttcaaa ttttcaaaat
     7201 atcttgattg caaaatacca tctgctaaca atttattttc ttgcacaatc gttgcattca
     7261 taaatgtaca ctctccatga aattttctag acatttcata aatcagtgta ttcacatggt
     7321 atttagcgtg tatgtgacta ggaccacctg ctagaggata gaagtgaaca tttcggacac
     7381 ttttactgtg aattaaatct actaaattac ttaaactttt cccccaagaa aagccaattt
     7441 tcatattatc atcaattaaa ttcctaagga cacctgctgc aacttgagaa attctttcag
     7501 ataaaattgt tggattatca tcaaattcat ttggaataat ttctaaactt tccagaccat
     7561 atttttcttt tacataattt tccaacttaa acatatttgt atcaaaattc tctatttcaa
     7621 ttttaacaat tcctgcattc cttgcttctg ttaacattct actaatagag gttctataaa
     7681 ttcctaattt tgctgctatt tgtgactgat ttaagttttc aatataatac agataagcaa
     7741 ttttagagag cagtttattc ctatcttgat tcatacactt aacctcttac gaaactacct
     7801 taaccattat cccagcattt tctaatgtag ctatattttg tttagaaagt ttttcgtctg
     7861 ttattacttc atagacttga cttaaagcaa atcttcttac tgtacccctt ttatcaaatt
     7921 tacttgagtc agttagtaca atgactttat ccgacgctgc tgaaatatat tgaactacct
     7981 cactgcgcat taaatctttt cctgtaaagc ccatctcttt atcgtaacca tctgtcccaa
     8041 caaaagcttg atgcacatga aaagtctgta tcatttcttt taataaaggt cccacagtaa
     8101 cctgtgaatc cttctgaaac tctccaccaa gaacaataat acgacatgaa tcataagctc
     8161 tcacaaaatt tgctataaaa aatgaatttg ttacaatcgt aacatttctt ttttgcttgc
     8221 aaatttcctc agcaagtaaa gcacaggtcg atccagattc tatcattatt gtttcattat
     8281 ctgacaccaa ttttactgct tcctgaacaa tttttctctt aatttcataa ttaattgaca
     8341 aacgtacatt taagtcatct ccactattta atacagcata tccatgctct ctgtgtaata
     8401 aaccttttga ctctaattta tctaaatctt ttctaatcgt tactttcgat acatttaatt
     8461 tttccgataa tgtattaacg tcgatctttt catattctga tactaattta ataatttgtt
     8521 ccaatctttt cattttacac ctccgtttta ttctaccaaa ataaaaagca aaaaacaaca
     8581 aatcaacctt tcgttcgtaa ttgtttttct ttcgtttttg tgataggata gacttatgaa
     8641 gaggaggaac tcttatggaa atatctaaag gaattatttt taatattcaa cacttttcaa
     8701 ttcatgacgg cccgggtatt cgtacaactg tttttttaaa aggatgtcct ctgcgctgtc
     8761 catggtgttc taatcctgaa tctcaaagaa tgaaacctga aaaaatgaaa gatgctcaac
     8821 gagagaaatt caccttagtc ggtgaagaaa agactgtaga agaaattatt acagaggtat
     8881 taaaagacaa agaattttac gaagaatccg gtggaggttt aactttatca ggaggtgaaa
     8941 tatttgctca gtttgaattt gctaaagcca tcttaaaatc agctaaagaa catcacatac
     9001 acactgccat tgaaactact gcctttgttg atcatgaaaa atttatcgat ttaattcaat
     9061 atgtggattt tatctacaca gacctaaaac attataattc tataaaacat aaaaaagtga
     9121 ctggggtttt taatcaaatg attattaaaa acattcatta tgctttttct caaaataaaa
     9181 ctatcgtttt aagaatccca gttattccta attttaacaa tagtttagag gatgcagaaa
     9241 aattcgctac tctatttaac tcattaaata tcgaccaagt tcaactactc ccttttcatc
     9301 aatttggtga aaacaaatat cgtttattaa atcggaaata tgaaatggat ggagtcaacg
     9361 cacttcatcc tgaagatctt attgattatc aaaaggtatt tctgaaccac catattaatt
     9421 gttatttcta gttcatttcc ttgaaatgct ctagctattt gcagataaca agcatctata
     9481 taaggttatc aaagaagact tccccatgac tctaaatgaa tatatcttac aatatcgcct
     9541 gaaacaagct atagataaga tggctgaatc tcccaactcc cctttaagcg ctatctctga
     9601 ccaagttgga ttttcagact ataaatattt tgccaaagta tttaaaaagt atctccatat
     9661 ttccccaaag aaattgaaat cactcggaag aatagtaaaa taggctattc ttctttttgt
     9721 agagaatttt actctaatat agtgaattga aataagatgt gaacatctct atcaggaaag
     9781 tcaaattaat ttatagaaat attttagcag tcaaagtgta ctgttataga ttcaatacac
     9841 tatagaatag aattgtaggt tttaaaaacg cttacattgt tttaaaataa acttaaataa
     9901 cacaacggag atatcccatc atgaaaaaga aatggatgta ttatgctgct tgttcttcta
     9961 atgaatctgc cgatgacagt tcatctgata aaggagacgg tggttcgcta gtcgtttatt
    10021 gaccaaactc agaggactta attggagcaa ctattcctgc ctttgaagaa aaatatggta
    10081 tcaaagtaga actgattcaa gctggtactg gagaactttt caaaaaacta gagtcagaaa
    10141 aagaagttcc tgtagctgat gttatctttg gtggttctta tacacaatat gctacccacg
    10201 gagaactctt tgaaaactat acttcaaaag aaaatgataa tgttatcaaa gaatatcaaa
    10261 acacaactgg cttctctact ccttatacac tagatggtag tgttttaatc gtccaccctg
    10321 atttaactaa aggcatgaac atcgaaggat atagcgacct tctcaaacct gaactaaaag
    10381 gaaaaatcgc aactgctgac ccagcaaact cttctagcgc ctttgctcaa ttaacaaata
    10441 tgctacaagc tcaaggtggt tacaaagatg ataaggcttg gtcttatgta aaagatcttt
    10501 tcacacttat tgatggtata gtaaaatgaa ataagaacag gacaaattaa tcaggacagt
    10561 caaatcgatt tctaacaatg ttttagaagt agatgtgtac tattctagtt tcaatatact
    10621 ataaaatcgg tttaagttca tctggtgtct ataaagcagt cgctgatgga gaaatgactg
    10681 ttggtctctc ttatgaagat ccagcagtta aactcttaaa tgacggagct aacattaagg
    10741 tagtctatcc aaaagaagga accgtcttcc tacctgctag tgctgctatc gttaaaaaat
    10801 ctaaaaatat ggaaaatgcc aagaaattta tcgattttat tatctctcaa gaagtacaag
    10861 atacacttgg tacaaccact actaaccgtc ctgttcgtaa aaatgctaaa acaagcgaaa
    10921 acatgaaacc aattgacaaa atcaaaacac tcactgaaga ttatgattat gtcatcaaga
    10981 ataaatcaga tatcgttaag aaatacaacg aagtctttac agatatccaa tctaaacagt
    11041 aaaagaggtt cactatgagt gagatcgaaa ttattaacgc caaaaaaatc taccacgatg
    11101 tctctgttat tgagaatttg aacattacaa ttccaaaagg aagtctcttt acccttcttg
    11161 gagcttcagg atgtgggaaa acgacccttc ttcgtatgat tgcaggtttc aacagtatca
    11221 aagatggaga attttacttc gatgatacaa aaatcaataa tatggaaccc agcaaacgca
    11281 atatcgggat ggttttccaa aactacgcta ttttcccaca tttgactgtc cgagacaacg
    11341 ttgcttttgg tcttatgcaa aagaaggttc caaaagaaga attgattcaa cagaccaaca
    11401 agtatcttga actcatgcaa attgctcaat atgcggatcg aaagcccgat aaactcagtg
    11461 gtggacaaca acaacgtgtc accttggcat gcgccttagc ggttaatcta agtgttctcc
    11521 tcatggacga gccacttagt aatctggagg ccaaacttcg cttggatatg cgtcaagcca
    11581 tccgagaaat ccaacacgaa gtgggaatta caactgttta tgtaacccac gaccaagaag
    11641 aagccatggc tatttcagac caaattgctg ttatgaaaga tggggtgatc caacaaatcg
    11701 gccgaccaaa agaactctat cataaaccag ctaatgagtt tgtggcaacc tttatcggac
    11761 gcacaaatat tatccctgcc aatcttgaaa aacggagcga cggcgcttat atcgtctttt
    11821 cagatggcta tgcccttcga atgctagctc ttgatcaggt tgaggagcaa gctattcatg
    11881 taagcattcg tcccgaagag tttatcaaag atgaatctgg agatattgaa ggaactatta
    11941 gcgatagcgt ctatcttgga ctaaatacgg agtatttcat tgagacaggt tttgcctcaa
    12001 aaattcaagt tagtgaagaa tcaacttttg aagaagatct acaaaaaggc aatcgtattc
    12061 gtctacgaat caatacgcaa aaattaaaca tcttttctgc agatggttcc caaaacctga
    12121 taaaaggagt caaccatgga acgtaaaaaa ctaaatattt ggacagcctc ctctttcttc
    12181 atctttctta cctatcttgt ctttctcgtt tatcctatcg ttaccgtgct caagtaagca
    12241 cttatacatg aaggacaatt ctcactagct aattttgtca ctttctttag taaagtctac
    12301 tactctgaga cactagtcaa cagtttcaag gtttccatta ccgctactgt cacttcctta
    12361 gttgtaggaa ccctattagc ttatctcttc tctatgtatg acttcaaggg ggagaaattt
    12421 ctacaaatat tgattatcat tgcttccatg tcagctcctt tcgtaggagc ctactcctgg
    12481 gttctcttgc taggacgaaa tggggtcatc actaaatttt tgacaaatgc ccttcatctt
    12541 ccagctatcg atatttatgg attcaaagga attgtacttg tctttacact gcaactattc
    12601 ccactggtat ttctatatgt tgctggaaca atgaacagta ttgacaattc tctacttgaa
    12661 gcagctgaaa gcatggggtc cttcggattt aagcgtatcg taacggttgt tttacctctc
    12721 ctagttccaa ccttactagc agttccttgc ttgtatttat gagagcattc tcagactttg
    12781 gaacgcctat gttgattggc gaaggatatc ggactttccc tgtcctgatt tatacccaat
    12841 ttattagcga ggttggagga aattctgctt ttgcaattat ggcgattatc attgccttgg
    12901 cgattttcct tatccaaaaa cacattgcaa accgctacag tttcagcatg aatctgctcc
    12961 atccaattga gcctaaaaaa actacaaaag gaaaaatagc tgccatttat gcaacagtct
    13021 acggaattat ctttatctct gttttacctc aaatctactt aatttatacc tctttcctaa
    13081 aaacatcagg tatggtatct gttaaaggtt attctccaaa cagttacaag gtagctttcc
    13141 atcgtatggg atctgctatt ttcaatacca ttcgtatccc tttgattgcc ttagttctag
    13201 ttgttctatt tgcgacattt atctcctacc tagccgttag aaaacggaat ttgtttacaa
    13261 acttaattga cagcctcagt atggtacctt atattgtacc aggaaccgtt ctagggattg
    13321 ccttcatttc ttccttcaat actggtctat ttggaagtgg atttcttatg attacaggga
    13381 ctgctttcat cttgattatg tctctatctg tcagaagatt accttatact attcgctcat
    13441 ctgttgctag cttacaacaa atagcaccaa gtattgaaga agctgctgaa agcttaggaa
    13501 gtagtcgtct caataccttt gctaagatta caactccaat gatgctatct ggtatcattt
    13561 ctggagccat cttatcttgg gtcacaatga tttcaaaact ctctacttct atcctcctct
    13621 acaatgtcaa aacaagaaca atgactgtag ctatttatac agaggttctc agaggaaatt
    13681 acggtgtagc cgcagccttg tcaactatcc tgactgttct aacagtaggt tccttgctct
    13741 tgtttatgaa aatctctaaa agcaatagca ttacacttta gttttccaca tcaaaaacag
    13801 ccgaaaggag taccctcggc tgttttttct tatcttgata ttcttatcaa atccctagct
    13861 catggcaagc aagtctagac tgattaaata gagccttctt ccatcttctc acgtcctagc
    13921 tctcggtaac tacggtcacc gacaacttca accctaaact gaccgtcctc atattcaaga
    13981 atcgtcacgc taccattatc tagaccatgc ggatgcatgc cattaatcag ataaacaatg
    14041 gttccaatag tcattccatg gctgacaaca agggcgttac ctccaccttg atcttccatt
    14101 tcttttgcaa tcatttcaaa gccttccttg attcggccac tgagtttttc ccagccttca
    14161 gcccaaccag ctgtatcgac ctctaccaag ccctcagcca gttcagcata agacaattgg
    14221 tgaacgtggt ccacattaaa gatacgagga ataatgccca tgaaaagatc gccatcatag
    14281 gctccatcaa aactaccgaa acaccattct ctgatacgct tgtccatgcg ataagggatt
    14341 ttcccctgca agccaagttc ttcaaggata attcccatgg tctgaatggt acgaccagaa
    14401 tcactcgaat aagcgcgctc aaactgtaga tcagattctc gcaaaccgat tcctaactct
    14461 tgaatccctc gttcaccttc agcagttaag ggagtatcgc tccaaccttg cgcgcgacca
    14521 atcgtgttaa acatggtctt gccatgacgt accaaataca atcgtacttt taccattttc
    14581 cgtcctccgt ttgcttctat tatatcatga atgataaaat aaaagccacc catacaggcg
    14641 acttttgaag gagattatta tgaaaaagtt taggagttca ttaaataaag atattagatg
    14701 aaaatcaaat tcaaactaat tcagtgttat ctgtttcaaa taatattagg aggtctttat
    14761 ttaatgatta tagtatacac gtctaatctt aaatagaact taaaatttct cctattttct
    14821 taatttttaa aactatgaat tggtgctggg atttgtccac cgcgagagat gaagtcgaca
    14881 gacgaagccc cattaacctt cataacaggt gcagttccta atagaccacc aaactcaatc
    14941 atatcgcctt ctcttccttt gggaatgata cgaacagctg ttgttttcat gttgataaca
    15001 ccgattgctg cttcatccgc aatcatagcc gcaatggttt cagcaggcgt atcttctggg
    15061 atggcaatca tatccaatcc aacagaacag atagccgtca tagcttctag tttttctaaa
    15121 ttaagagagc cattttgcac tgcagcaatc attccttcat cctcagaaac agggataaag
    15181 gcaccagata aaccaccgac ttggttgcag gccatcactc cacccttttt aacttggtcg
    15241 ttcaagaggg ccaaggcagc cgtcgttcca tgcgtgccaa ctgtttctag ccccatttcc
    15301 tcaaggacac gtgccacaga gtctccaacc gcaggggttg gtgccaaact caagtccaca
    15361 ataccaaact ccacacccag tctctcactg gccatttgac caaccaattg accgatacga
    15421 gtgattttaa aggcagtttt cttaactgtt tcggctacta catcaaagct ctgtccacga
    15481 actttttcca aagcacgttt cacaacacca ggaccagaaa ctccgacatt gatgataaca
    15541 tctgcttccc caacaccatg aaaggcaccc gccataaatg gattgtcctc aacagcatta
    15601 gcgaatacaa ccaacttggc cactcccata tctgaaagat ttgctgtttc cttgataatt
    15661 cgtcccatat ctgccacagc cgtcatatta ataccagact tggttgagcc gatattgact
    15721 gacgagcaga ccttatccgt ctcagccaaa gcgcgaggaa tggaattgat gagaatctca
    15781 tctccctttt gataaccttt ttgtactaag gcagaaaaac caccaataaa gtccacacca
    15841 atctctttcg cagccttatc aagcgctttt gccagaacca cgtagtccgt cgcatctgtc
    15901 gctgccccaa tcagagaaat aggtgtcacc gatacacgct tattaacgat aggaattccc
    15961 aactcagccg caatttcatc accaacagct actaaattag ccgcctttgt cgtaattttt
    16021 tgatagattt tctccgcagc acgattgata tttggatcga tacagtccaa aagagaaatc
    16081 cccatggtaa tggttctaat atcgaagttt tgctcctcaa tcatggcgat ggtttcagta
    16141 acttgtctaa tatccatgat gacctcctag atattataca tagcttcgaa aatcgctgca
    16201 ctctgaatat tgatttttac attcaaagtt tgcccaaaag cttcaaattc attacgaaga
    16261 taggtaaaat cttgcttttc atcactagat acaacagcca tcatcgtaaa atattcatcc
    16321 aatacagttt gagagatatc gtcaatattc aatcctaatt ctgcaatttt accagaaaca
    16381 cctgcaacaa ttccagattt atctttacca acaacagtta taatcgcttt cataagtaaa
    16441 ctccaattct tcttaaaata agaaacctta acattaaaca ggattctttt caaatagtat
    16501 agcataattc taacgaaaat actcaaaaac gcctgcttac gaagttgttc ttaagaaaaa
    16561 aacaatttcg taaacaagcg tctactatcc caacttatga tgagtgttcc cgctaggacc
    16621 gaaatcctag cggtagacca gagctagact aagagcacaa gactccatca tcataacact
    16681 caacaaaatt gatgatttta tactaattcg atgatcgcca ttggcgctgc atcaccacga
    16741 cgtggttcag ttttaaggat acgagtgtat ccaccgttac gttcagcata acgaggtgcg
    16801 atttctgaga acaatttttg aagtgctgta gtagaagtgt acttatcagt tgcttcatca
    16861 tagttttcag atgcgatttc attacgtacg aaagcagctg cttgacgacg tgcatgcaaa
    16921 tcaccacgtt tacctagagt aatcattttt tcaacagttt tacggatttc tttagcacga
    16981 gcttcagttg tcacgattga ttcgttgatc aaaaggtcag ttgtcaaatc gcgaagcatt
    17041 gctttacgtt gtgagctagt gcgtcctagt ttacggtaag ccatgtattc ctcctttatt
    17101 tatcttttaa tccaagaccc aaatcaatga gtttgagttt cacttcttcc aaactcttgc
    17161 gtccaagatt tcgtactttc atcatctctg cttcagattt ttctgtcaaa tcatgcacag
    17221 tattgatacc ggcacgtttt aaacagttgt atgaacgcac agacaagtcc agttcctcaa
    17281 tcgtacgatc taaaatacgg tcgtcagatt cagtatcagc ttctttcatc acttcagttg
    17341 acttagcaat ctcagtaaga tttgtaaaca aatcaagatg ttctgtcaaa atacgtgctg
    17401 aaagccctaa agcatcttct ggaataattg ttccatttgt caagatttca agggttaatt
    17461 tgtcgaaacc atcattgcta cctacacgag caggttccac ttgatagttg acttttgtaa
    17521 ctggtgtata aatagaatct acagcaagtg ttccaactgg tgcattatcc tttttatttt
    17581 catcagcagg tacatatcca cgaccactgt taacagtcat agtcgctttt agagaagaac
    17641 cttcaccgat tgtaaagaga taatgatctg gatttacaat ttcaatatcg ctatctgtca
    17701 aaatgtcacc agctgttact tcagcaggac cttcaacatc cagttcgatg attttttcgt
    17761 cttcaacgta cgatttcact gcaattcctt taatgttcag aatgatttgc atcacgtctt
    17821 cacgaacacc tggaactgtg tcaaactcat gtaacacacc atcaatgttg atagatgtca
    17881 cagctgctcc tggtagagaa gctagaagta cacgacgaag agagttacca agagttgtac
    17941 cgtagccacg ttcaagtggt tcgattacaa acttgccata atctttattt tcatcaattt
    18001 ttgttatatt tggtttttca aactcgatca tttagttact ccctcttaaa cgaaaagcag
    18061 tgtaatgcga tgattataca cggcgacgtt ttggaggacg agcaccattg tgtggcactg
    18121 gagtcacatc acgaattgct gttacttcaa gaccagcggc agcaagcgca cgaatagctg
    18181 actcacgacc agaacctgga ccttttacag taacttcaac tgatttaaga ccgtgttctt
    18241 gtgcagattt agcagcagct tcagaagcca tttgagcagc gaatggtgta gatttacgag
    18301 aacctttgaa accaagagca ccagctgatg accaagcaat tgcattacca tgcacatcag
    18361 taatcataac aatagtgtta ttaaatgtag cgtgaatatg agcaatacca gattcgatat
    18421 tctttttcac acgacgttta cgtgttggtt tagccaagac ttttacctcc tatattattt
    18481 tttcttacca gcaatcgcaa cagctttacc tttacgagtg cgagcgttgt ttttagtatt
    18541 ttgtccacgg acaggaagtc cacgacggtg acggatacca cggtatgaac cgatttccat
    18601 caaacgtttg atgttcaagt ttacttcacg acgaaggtca ccttcaactt tgattgcatc
    18661 cacttcacga cggatagcat cttcttgatc tgatgtaaga tcacgtacac gaacatcttc
    18721 tgagattcca gcagcagcca aaattttctt agatgttgca agtccgatac cataaacata
    18781 agtcaatgag attactacgc gtttgtcatt tggaatatca actccagcaa tacgagccat
    18841 gttttctcct ttctatctta tccttgacgt tgtttgtgtt ttggatttgc tgggcaaatt
    18901 accataacac gaccattacg acgaataact ttacagtatt cgcaaattgg tttgaccgat
    18961 ggtcttactt tcatttctta tccctccaag tttttcgatt atttaaagcg gtaagtgata
    19021 cgtccacgtg tcaagtcata tggactcatt tcgacagtaa cacgatctcc cgctaaaata
    19081 cgaatatagt ttttacgaat tttaccagaa actgttgcta aaatctgatg tccattttca
    19141 agttcaaccg taaacattgc attcggcatt gtatcaacta ctttgccttc aacttcaatc
    19201 acatcgtctt ttgccacgca aaagcacctc cataaatttc gatttgatgc ctctagacac
    19261 agagacaaca attataagtc agactatttc agtataacat ttgtagcgga tttttgcaag
    19321 tgtgaaaaac gctttatttc aaatttgtca atactttttc aatatctgag aagacatcat
    19381 tgatatcttg attaccttcg atgtcatgaa ccaaaccttt ggcacggtag tgagcaatga
    19441 ttggttctcc ttgagcaata ttaacatcca aacgacgttt tactgtctca ggcttatcat
    19501 cttcacgttg gtagtaatct tcttctttat agtcaactgg tgggttaaag accttgtgga
    19561 aagtttctcc agttacgcgg tggatgatac ggccactcaa acgttccaag aggctgtcag
    19621 ggttcacttc aatattgata ataccttcta gttcaatgcc aagttcagcc aatgttttgt
    19681 ccaaggcatg agcttgttca attgtacgtg ggtaaccatc caataagaat cctgtttctt
    19741 taatatcatc ttgtgaaagg cgttctttta cgattccatt tgtaacttcg tcaggaacca
    19801 attcaccctt gtcaatatat gacttagcaa gaacacccat ttcagtttga tttgccattg
    19861 cagcgcggaa catatcacct gttgagatat gtgcaacatg gaattgttct acgatttttg
    19921 ctgcttgagt tcccttacct gcaccaggta agcccataat caaaagattc atgatttgat
    19981 ctccttattt tatttttaaa tagaagcaaa aagtcttttc acccctattt aaaaacaaaa
    20041 tagaagaggg gagatccaac tcttacaaat gtcagagttt aaacctccac tccctcagta
    20101 tttactgatt cagtaaatac ttttattctg ttctgtccat gaaaccaaca tacttacgtt
    20161 tcaataggta accttccaat tgcttgattc cttcgatacc tgtagagata atgatcaaga
    20221 gacttgttcc accaaaggca acaacatcag aaagaccaaa tacatcttta gctgcaatcg
    20281 gtaaaatgga aatcacacca agaaagaggg aaccaacagt tgcaagacga cgaagaagtt
    20341 tagacatata ttcttctgta cctttaccag gacgaactcc atggatatag gcaccactct
    20401 tttgtaggct ctctgctgct ttttcaggat taatctgtac aaacgtatag aagaatgtaa
    20461 agagaataat caacaaagca tacatggcaa taccagttgg agaagtagtt gccaacatct
    20521 cttgtgctac ccttacccaa gcccaatcat gacctgtggc actcaaaaac tgaagaatag
    20581 ccgcaggcgc tgcagtaatc gaactggcaa agataacagg gataactcca gcagggttta
    20641 cctttaacgg aaggtaagag ctagatggag caccttgtgc aaccttagta tattggattg
    20701 gaattttgta ttctgcttgt tgaacataag ttgtaaagta aataatcaac aatacagtaa
    20761 taatcaaaat gattacgaaa atgatagatg aagtgatacg gctacttggg acgttcacaa
    20821 agtagtccac atagatgccc tgaatcatct ctggaattga ggaaacaatc ccggcaaaga
    20881 taatcatgga aacaccgttt ccgtatccct tatctgtaat ttgctcaccc aaccaagtga
    20941 caatcatact accagctgtt aagatgatac caatcgtcag aaaaacttgt ggagttaaag
    21001 cagttttaat caattgagct ccagccaagg tattaaaacc agctgtaatc ccgatagatt
    21061 gcacaaaagc gagaactaga gcaatataac gagtagcttg attcaatttt cttcgaccta
    21121 cttccccttg tttaccccac tctacaaact tgggtaaaat atccatttgc aagagttgga
    21181 caacaataga agcggtgata tagggactaa ctcctagggc aaaaatcgaa aagtttttta
    21241 gggcattccc cgacaccaag ctcaacatgt ttaagaagga taatccactt aaagcattca
    21301 agctattggc attcacacca ggaactgtaa tgctagttcc gatacgaaag accaaaacga
    21361 taaaaattgt aaataaaatt tttgatcgaa cctgcttgac tttaagagct tctcttaata
    21421 atttaaaaaa cataggtcac ctctcttaga tgacttctac tgaaccacct ttagcagtga
    21481 tagcttcttc agctgattta gagaatttag ctgctttcac agtcaatttc ttagtcaact
    21541 caccgttacc aagaatttta atacctgact tttcagcttt aacaattcct gcttcgataa
    21601 gaacaactgg agttacttca gcaccatctt caaagacgtt caattggtca aggttcacaa
    21661 ttgcgtattc tttagcgttg atgttagtga atccacgttt tggaagacga cggaacaatg
    21721 gagtttgtcc accttcaaaa ccaaggcgaa ctccgccacc gctacgagct ttttgacctt
    21781 tttgaccacg accagatgtt ttaccgttac ctgatgaagt accacgacca acgcggttac
    21841 gtactttacg agaaccttct gcaggtttca attcatgaag tttcattttt attttctcct
    21901 cttttgtaaa atgctagcgc cgataaggga gaaaaggttg tctcccccat caactcgcct
    21961 atacgatgtc atcatagatg actatatcta gttttagggg atggtacagt gcacatcccc
    22021 taaaacttca ttagtttact tcttcaactg ttactaagtg agatactgct gtaatcatac
    22081 cacggatagc agcgttatct tctttaataa cagagctgtt caatttgcca agtccaagtg
    22141 ctacaacagt tttacgttgt gatggaatgc gtccgattgg agacttagtc aaagtaattt
    22201 taatttgagc cattttatcc cctttcttat gccaaatcag aaactgaaat accacgaagg
    22261 gcagcaattt cttcagcgcg tttcaattgt ttcaaacctt caacagttgc acgaacaatg
    22321 ttgattggag tgttagaacc aagtgattta gatgtaatat ctgccacacc tgccaattcc
    22381 acaacggcac gaactgcacc accagcggca actccagaac cttctacagc aggtttcaac
    22441 aatactttag ctccaccgaa ttctgaaaga acttcgtgtg ggattgttgt tccaaccata
    22501 ggaacttcga tcaagttttt cttagcatca tctactgctt tacggattgc ttctggaact
    22561 tcttgagctt taccagtacc aaatcctacg cgaccattgt ggtcaccaac aacaacaaga
    22621 gctgcgaaac gaagacgacg tccaccttta acaacttttg taacacggtt gacagcaact
    22681 acgcgttctt ctaattcaac tgcattgtct ttaaatgcca ttttctagtg tcctcctatt
    22741 agaatttcaa tccgttttca cgagctgcat cagccaaagc tttcacacgt ccgtgatata
    22801 gatatccacc gcggtcgaac accacttctg aaataccttt agcgtttgca cgttctgcaa
    22861 cgagtttacc gacagcaacg gcttgttcag ttttagttcc ttttgaaact tctttatcaa
    22921 gagttgaagc acttgcgagc gttacacccg ctacgtcatc aatcacttga gcgtagatgc
    22981 ctgtattaga acggaatacg ttcaaacgtg ggcgatcagc agttccagag agttttccgc
    23041 gaacgcgacg gtggcgtttt tggcggagtt tgtttttatc tggttttgaa atcacagttt
    23101 tcacctcttt agttttaaat cgtgtgctat gcacaaagtt ggaaaatagg ttggtggttg
    23161 atgatcaacc actcaacatt atttacctgt tttaccttct ttacggcgaa cgaattcacc
    23221 aacgtaacgg atacctttac ctttatatgg ttctggtgaa cgaaggctac gtacgtaagc
    23281 agctgtttga ccaactactt cttttgaaat tccgctaaca acgattgttg ttgggtttgg
    23341 aagttcaaaa gtaattcctt ctggagcttc aacttcgtct ggatgagatt taccaacagc
    23401 caaaacaagt ttagatcctt gaagctgtgc acggtaacca accccacgca tttcaagttc
    23461 tttcttgaat ccttctgata caccaacaac catgttgttc aaaagggcac gagtagttcc
    23521 gtggatagtt ttcatttctt ttgaatcgtt tggacggtga agagttattt cagtaccttc
    23581 cacacggatt tcaatatctt ttgagaactc acgagtaagt tctcctttag gtccttttac
    23641 agttacaacg ttgtcattgt tagcgagttc aacaccagca ggcaacacga taactttatt
    23701 accaatacgt gacatgttta ttttctcctg ttaaattgtc aggccagaac ggccagtttt
    23761 cacggggttc agatacttat ttagttcaag agctgaactg aacacgctct aagaactgtg
    23821 caaaatagat aagttggctt gtttgtaaac aaacttctcc aacttcctaa ttttgctttg
    23881 ttctttacga gctttgtatc ttgattttac caaacgtaag cgataacctc accaccaaca
    23941 ttcttttggc gtgcttcttt atcagtaagc aaaccttcag aagttgaaag gatggcaatt
    24001 ccaagtccgt taagaacttt tggaaggtct tcacgttttt tgtagacacg aagtcctggt
    24061 ttagaaacac gtttcaagtt agtgataact ttctcaccat ttggtccgta tttaagaaat
    24121 acacggatga cgccttgttt gtcatcttca atgatttcaa cgttttttac aaaaccttcg
    24181 cgtttaagga tttcagcaat cccttttttg atgtttgatg caggtacttc aagtacttcg
    24241 tgtttagctt ggttagcatt acgaatacga gttaggaagt ctgcgattgg gtcagtcata
    24301 accattttgt ttttctcctc ttactagtag tttgcaagtt gcacttgcta gttaatacat
    24361 gatacaaaga gcgtaacagc acgagcaaaa atagacaatt taatgcagaa gcaatgctcc
    24421 aaagcaaatt agtctttttt gccaaagctg tagctcgtgt tcaaattggc aagcccaatt
    24481 gaacccgggc taaactctgt gtgaaaaaga taaactttcc tagaaacttt agtttcttcg
    24541 tcaagtttcc tatttttact tggagttttg acgctcttga tatcttaaat taccaagatg
    24601 cttttgttac accaggaatt tgacctttat gcgcaagttc gcgaaaagcg atacgactca
    24661 gaccaaattt gcggtaaact gaatgtgggc gccccgtaac cctacaacga ttatgtaaac
    24721 gagtcggtga ggcgttgcga ggtaatttag ataaaccttc gtagtcccct gccgccttta
    24781 atgcagcacg tttttcagca taacggtcaa caattttttg gcgtttagcc tctctagcta
    24841 ccattgattt tttagccatt agatttacct cctatattat tttgcaaaag gcattccaag
    24901 gcctgtaagc aatgcacgtg actcttcgtc agtgttagca gttgttacga taacgatgtc
    24961 aagaccacga gttttgtcaa cgtcatcgaa gttgatttct gggaagatta attgttcttt
    25021 cacaccaagt gtgtagttcc cgcgtccatc aaatgatttt gttgggacac cgtggaagtc
    25081 acgtacacgt ggaagtgaaa ctgataccaa tttatccaag aattcgtaca tacgttcacc
    25141 acgaagggta acttttgcac cgatcgcaac accttcacga agacggaagc cggcgattga
    25201 ttttttagct ttagtgataa gtggtttttg acctgagata agtgccaatt cttcagcagc
    25261 tttttcaagg cttttagcgt ttgatacagc ttcaccaaca cccatgttca aaacaatctt
    25321 atctacttta ggcacagcca tcactgatga gtagttgaat tgttctgtca aagcaggaac
    25381 tacttcatta agatattttt cttttaaacg atttgccatt atacttctcc tttccttcgt
    25441 gattaatcaa gcacttcgcc tgattttttg ttgtagcgaa cttttttacc gtctacaaat
    25501 ttgtaaccaa cacgaccagc tacaccattt ttgtccaaaa cttgaacatt tgatacgtgg
    25561 atagctgctt ctttctcgat gataccacct tgaggaagct cgttagttgg acgttggtgt
    25621 ttcttaacaa tgttaacacc ttcaacgata actttgttta cttttggaag ggcagtaagg
    25681 acaacagctt ctgttccctt atctttacca gcgattacgc gaactttgtc gccttttttt
    25741 acaaacatta ggtttctcct tgatttttct tacgcccata agggcaccct agcttgaagc
    25801 taggggacta gtttgttcct aaaaattaaa gtacttctgg agcaagtgac acgatcttca
    25861 tgaaaccacc ttcacgcaat tcacgtgcaa ctgggccaaa gatacgtgtt ccgcgaggag
    25921 ttttgtcttc acggatgata actgctgcgt tttcgtcaaa tttgatgtat gaaccatcag
    25981 cacgacgagc acctgattta gtacgaacga taactgcttt aacaacgtca ccttttttaa
    26041 ccgcaccacc aggagtagct tgttttacag atgccacgat aacatcaccg atgtttgcaa
    26101 atttacgtcc tgaaccacca agaactttga tagtcaagat ttcgcgagca ccgctgttgt
    26161 ctgcgacttt caaacgagtt tctgtttgaa tcatttcagt tttctccttt caggtttgat
    26221 tagatgatga ccgcttcttc aacaacttct acaagacgga aacgttttgt agctgaaagc
    26281 gggcgagttt ccatgatacg tacgatatcg ccttctttgg caacattgtt ttcatcatga
    26341 gctttgtatt ttttagagta gttaatacgt ttaccataga ctgggtggtt acgttttgtt
    26401 tcaactacaa ctgtgattgt cttgtccatt ttgtcagata caacacgtcc aacaagaact
    26461 ttacgattat tgcgttccat tgaaatttct ccttccctag tctattattt cgcttcagat
    26521 tgaactgttt tgatacgagc gatttgtttt ttaacttctt tcaagcgagc tgtttgttcc
    26581 aattgaccag tagcagcttg gaaacgaagt tcaaacaatt cttttttcaa ttcgttttcg
    26641 cgcttcgcga gttcttcttg agaaagacca cgaagttctt taacaaattc ttttacttca
    26701 ttaagtttca tgccttctcc ttattctgct tcacgtttta cgaatttaca tttaactggc
    26761 aatttgtggc tagcaagtcg aagcgcttca cgtgcaatct cttcagatac accagcgatt
    26821 tcgaacatca ctttaccacg tttaactggt gctacccaac cttcaggtgc ccctttacca
    26881 gatcccatac gcacaccgat agctttagca gtgtatgatt tgtgtgggaa gattttaatc
    26941 caaactttac caccacgttt catgtaacga gtcatggcga tacgagcagc ttcgatttgg
    27001 cggttagtga tccagtggct agttgtagct tgaagaccgt attcaccgaa tgctacttct
    27061 tttccacctt ttgcttcacc gcgcattttt ccacggaact cacgacggtg tttaacacgt
    27121 ttaggtacta acattggtta tttacctcct ttagtgtttt tacgagctgg aagaacttca
    27181 ccacggtaga tccatacttt aacaccaagt ttaccgtatg tagtatctgc ttcttcccaa
    27241 gcgtaatcga tatctgcacg aagtgtgtga agcggaacag ttccttcaga gtatccttca
    27301 gcacgggcga tatctgcacc gttcaaacga cctgatactt gagttttgat tcctttagct
    27361 ccagcacgca ttgcacgttg gattgcttgt ttttgtgcac gacggaaagc aacacgttgc
    27421 tccaattgac gagcaattcc ttcacctaca aggtgagcat ccaaatcagg ttgtttgatt
    27481 tcgatgatgt tgatgtgtac ttgttttcca gtcaatttgt taagttttgc acggagtgca
    27541 tcaacgttag caccaccttt accgataacc atacctggtt tagcagtgtg aagtgaaacg
    27601 ttaactttgt ttactgcgcg ttcgatttca atagttgaaa ctgctgcgtc agcaagttct
    27661 ttttgaacga atttacggat tgcaagatct tcatgaaggt aatccgcgta ttctttttca
    27721 gcataccatt tggcatccca atcacggatg atgccgacac gcataccaat tggatgtact
    27781 ttttgaccca cgattttacc tccttatttt tctgcaacag ctacagtgat gtgagctgta
    27841 cgtttgttga ttggtgaagc tgaacctttc gcacgtggac ggaaacgttt catagttggt
    27901 ccttcgtttg cgaatgcttc agatactacc aagttagctt tatccaaacc aaagttgttt
    27961 tcagcgttag ctacagctga gttcaaaact ttcaagatga tttcagcagc tttgtttgga
    28021 gtgaatgtca agattgcgat tgcatcggct acgcttttac cacggatgtt atcaagaaca
    28081 agacgtgatt tacgaggtga aacacgtact gtacgagcca ttgctttagc tgaagtaatt
    28141 tctgccattt atgttctcct tattttctac gtgttttctt gtcgtctgca gcgtgacctt
    28201 tgtaagtacg agttggtgca aattcaccaa gtttgtggcc taccatgtct tcttggatgt
    28261 aaacaggtac gtgtttacgt ccgtcataaa ctgcaatagt gtaaccaatg aaacttggga
    28321 agatcgttga acgacgtgac caagttttaa taactttttt cttttcgtcg ttagcttgag
    28381 cttcaacttt tttcatcaaa tgctcatcga cgaaaggtcc ttttttaaga ctgcgtccca
    28441 tttttatatt ttctccttta aatgttgtac cacagcggct tgcactccta tggagcgcta
    28501 ccgagctggc ggatttacta gttgcttaag cgactagttt aatattattt ctcgttgcga
    28561 cgacgaacga taagtttgtc agatttcgct ttcttgttac gagttttaag accaagagca
    28621 ggtttgcccc atggagtaga tggtgcttta cgaccaactg gtgctttacc ttcaccacca
    28681 ccgtgtgggt gatcgttagg gttcattaca gaaccacgaa ctgttgggcg gatacctttc
    28741 caacggctac gtcctgcttt accaaggttt acaagtccat gttgttcgtt tccgacaaca
    28801 ccaactgtag cacggcaagt tccaagaatc atacgaactt cacctgattg aagacgaaca
    28861 agaacatatt taccttcaga acccaatact tgagcagatg caccagcagc acgtaccaat
    28921 tcaccaccac gacctggttt caactcgatg ttgtgaatca aagtaccaac tgggatgtta
    28981 gcaagtggaa gagcgtttcc gactttgata tctgcttctg gacctgaaac gatacgttga
    29041 cctacttcaa gaccttttgg agcgatgatg tatgctttca caccgtcagt gtagtgtaca
    29101 agagcgatgt ttgcagaacg gtttggatcg tactcgattg ttttaacaac tgcttcaacg
    29161 ttgtctttat tacgtttgaa gtcaaccaaa cggtagaaac gtttgtgtcc accaccttgg
    29221 tgacgaactg tgatacgacc gttgttgtta cgaccagcct tgctcttcaa tgcaacaagc
    29281 aatgattttt caggagtgct tgttgtgatt tcagcgaaat ccaaagaagt catattacgg
    29341 cgaccgtttg ttgttggttt ataaacacga attcccacga tatttcctcc ttagattatt
    29401 cagcttcagc agcaaacaac tcgattgctt tagaatcagc tgtaagtgtg atgatagctt
    29461 ttttagtttt gttagtaaaa ccagtgtaac gtccaacacg tttagctttt ggttttacgt
    29521 tgattgtgtt aacattggca actttaacac cttcgaaagc agcttcaaca gcttgcttga
    29581 tcaaaagttt gtgtgcacga gtgtcaactt caaatacata tttccctgct tcaagttgag
    29641 ccattgagct ttcagtgatg acaggttttt tgataacatc atacaaattc attatgcaag
    29701 aacctcctcg attttagaga tagctgcttg tgtgacaaga agtttgtcgc tatttgcgat
    29761 gtcaagaaca cttgcagttg tagcagttgc aactttcacg tttggaaggt tacgagctga
    29821 aagagctgcg aattcatttc cttcttcaag gataacaaga actttagaat cgatgctcaa
    29881 tgctgcaaga acttttgcaa attcagcagt ttttggagct gtaaatgaaa gagcgtctac
    29941 agctacgaat ttgttttcag caactttttc agagtaaact aatttaagag ctaggcgacg
    30001 aactttttgt ggaagtttgt agccgtatga acgtggagtt ggtccgaaga caacaccacc
    30061 accacgccat tgtggtgagc ggatagaacc ttgacgagca cgtccagttc ctttttgacg
    30121 ccatggtttg cgtccaccac ctgatactgc agagcggttt ttaacagcgt gtgttccttg
    30181 acgaaggctt gcgcgttggc tgatgattac atcaaacaca actgattcat ttggttcgat
    30241 accaaatact gcatcgttaa gaacaacttg gccagcttct ttaccagttt ggtcaaataa
    30301 tgttacgttt gccattgtga ctgatttccc ctttctttat tatttaccag ctttaactgc
    30361 tgatttgata gtgataagag atttcttagc acctggtacg ttacctttga taaggataac
    30421 gttcttttct ggaacaactt gtacaacttc aaggttttga attgttacgc ggtcgccacc
    30481 catacgtcct gcaaggtttt tacctttgaa tacgcggtta ggtgcaacag gccccataga
    30541 acctggacga cggtggtaac gagaaccgtg agccattggt ccacgtgatt gtccgtggcg
    30601 tttgataaca ccttggaaac ctttaccttt agaagtacca gttacatcaa caacatctcc
    30661 agctgcgaat gtttcaactg tgatttcagc gccaacttcc aagccttcaa cgtttttgaa
    30721 ttcacgaatg aagcgcttag gagccgtgtt agctttcgct acatgtcctt tagcaggttt
    30781 gttgctcaat acttcgcgtt tgtcatcgaa accaacttgg atagcgttgt atccgtctgt
    30841 ttcaacagtt ttaacttgaa gaacaacgtt tggagttgct tcaataactg ttacagggat
    30901 caattcgcca gcttcagtga agatttgagt cattcccact tttttcccta agattccttt
    30961 tgtcatgaga aaatagttcc ttttctatat tttttattca aaaagttttt aacgagcgtt
    31021 ttttatgctc aagtctaaga tacaaagggc gtcaaactca aagtgaaaat aggaaactaa
    31081 cgcagtgtct agcggacaat aggaagttta tctttttcac accgagttta gcccgtgttc
    31141 aattagattg aaacaccagc ctctgctctt ttatatttta gattaaagtt tgatttctac
    31201 gtttacacca cttggaagat ccaatttcat caaggcatca actgtttttt gagttgggtt
    31261 aacgatatcg atcaaacgtt tgtgtgtacg catttcaaat tgttcgcgag agtctttgta
    31321 tttgtgagtc gcacgaatga ttgtgtagag gctacgttca gttggaagtg ggattggacc
    31381 cgcaacttgt gcacctgtac gagtagctga ttctacgatt tttgcagccg ctgtgtcaag
    31441 cgtacggtgt tcgtaagctt tcaaacggat acggattttt ttgtttgcca tctttttctc
    31501 cttttcgtct atttaagata ataggctagc tccacaagaa aaccgacgcg gtgttgcgtg
    31561 gcaatgcaac cgagcgtgtc gcaacctctt gcatcaaaac taaggctgta atttacagca
    31621 ccataataga ataacacaaa tcccctgcga ttgcaaggga tttgttaggt tttttcgttt
    31681 ttttgggatg aaactgtttt cctacttttt ctttctaaaa ttagggattt tcttctatat
    31741 ttcttctata cataagttaa gtcctcttga catcaaattt atcttctgat tggtccacta
    31801 agatatccgc cttagactca gtttctttat agtatcgcag atactgctcc cgtctcatct
    31861 gatggctagc caatataaag gatgcatagc gatttctcac agtcgtatct ctagcaaggc
    31921 gtcgctttaa ttcggtctcc tcatccgtgt agaaacagat ggttttttca aagagttcct
    31981 tgggtagaaa accaacagac atcccttcga caatcaaaat tggtttggct ccagacaaga
    32041 cctcactagc cttccaaggt tcttcaattg tcaagacatc catacccgcc tgcaaggcaa
    32101 ggatatctct ctgcaaactc tccagttcat gcgccactgg cagactggct gtcacctttt
    32161 gattcggcgc gtccttgggt actaccaaat agcgtccgga ggtgatatag ggatctgttt
    32221 ctagcaaatt ta
//
LOCUS       DAVHLA010000023        32072 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVHLA010000023 DAVHLA010000000
VERSION     DAVHLA010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32072)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32072)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32072
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.023"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(18..740)
                     /locus_tag="VVO77_001201"
     CDS             complement(18..740)
                     /locus_tag="VVO77_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEU5693217.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DINTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTC
                     KPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            complement(1053..1283)
                     /locus_tag="VVO77_001202"
     CDS             complement(1053..1283)
                     /locus_tag="VVO77_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEU5693218.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAVLGAMIVLAIFWRRGS"
     gene            complement(1293..2534)
                     /locus_tag="VVO77_001203"
     CDS             complement(1293..2534)
                     /locus_tag="VVO77_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEU5693219.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDLLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEGFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVIFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSLVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            complement(2556..2708)
                     /locus_tag="VVO77_001204"
     CDS             complement(2556..2708)
                     /locus_tag="VVO77_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693220.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            complement(2729..3007)
                     /locus_tag="VVO77_001205"
     CDS             complement(2729..3007)
                     /locus_tag="VVO77_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HEU5693221.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            complement(3000..3263)
                     /locus_tag="VVO77_001206"
     CDS             complement(3000..3263)
                     /locus_tag="VVO77_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEU5693222.1"
                     /translation="MSKMSMSIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQVLTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            complement(3365..7756)
                     /locus_tag="VVO77_001207"
     CDS             complement(3365..7756)
                     /locus_tag="VVO77_001207"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEU5693223.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VDKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     GAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNEIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEAIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            complement(7860..9941)
                     /gene="fusA"
                     /locus_tag="VVO77_001208"
     CDS             complement(7860..9941)
                     /gene="fusA"
                     /locus_tag="VVO77_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEU5693224.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     SKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            complement(10366..10836)
                     /gene="rpsG"
                     /locus_tag="VVO77_001209"
     CDS             complement(10366..10836)
                     /gene="rpsG"
                     /locus_tag="VVO77_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEU5693225.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            complement(10856..11269)
                     /gene="rpsL"
                     /locus_tag="VVO77_001210"
     CDS             complement(10856..11269)
                     /gene="rpsL"
                     /locus_tag="VVO77_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEU5693226.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            11686..15483
                     /gene="spuA"
                     /locus_tag="VVO77_001211"
     CDS             11686..15483
                     /gene="spuA"
                     /locus_tag="VVO77_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEU5693227.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWHLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSK
                     PEHQNEASHPAHQDLAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQASSV
                     KEAVRNESVENSSKENIPATPDRQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNK
                     KEN"
     gene            complement(15583..16632)
                     /locus_tag="VVO77_001212"
     CDS             complement(15583..16632)
                     /locus_tag="VVO77_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEU5693228.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SDGRSEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHIPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            16689..16826
                     /locus_tag="VVO77_001213"
     CDS             16689..16826
                     /locus_tag="VVO77_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693229.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEVVDRTNEVSNHTYGKATLTWFEEI
                     F"
     gene            complement(16903..18711)
                     /gene="glmS"
                     /locus_tag="VVO77_001214"
     CDS             complement(16903..18711)
                     /gene="glmS"
                     /locus_tag="VVO77_001214"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEU5693230.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYFEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     VDSQDPEVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            complement(18904..20283)
                     /gene="bglA"
                     /locus_tag="VVO77_001215"
     CDS             complement(18904..20283)
                     /gene="bglA"
                     /locus_tag="VVO77_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEU5693231.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPDSPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            complement(20383..22236)
                     /locus_tag="VVO77_001216"
     CDS             complement(20383..22236)
                     /locus_tag="VVO77_001216"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEU5693232.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            complement(22249..23508)
                     /gene="rseP"
                     /locus_tag="VVO77_001217"
     CDS             complement(22249..23508)
                     /gene="rseP"
                     /locus_tag="VVO77_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEU5693233.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTVLPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPKDSQG
                     RYLLGVQPGGKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            complement(23530..24333)
                     /locus_tag="VVO77_001218"
     CDS             complement(23530..24333)
                     /locus_tag="VVO77_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEU5693234.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            complement(24342..25100)
                     /locus_tag="VVO77_001219"
     CDS             complement(24342..25100)
                     /locus_tag="VVO77_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEU5693235.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            complement(25331..25795)
                     /locus_tag="VVO77_001220"
     CDS             complement(25331..25795)
                     /locus_tag="VVO77_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEU5693236.1"
                     /translation="MAAGSVRNFIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLE
                     KKLREDFPQYQWELKNQVYMHQHSPHTASYTSSRDAMSKYPERCTAVGLRLNEESDFE
                     LYAPYGLEDILNFQVRPTPHFLENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            complement(25884..26855)
                     /gene="ruvB"
                     /locus_tag="VVO77_001221"
     CDS             complement(25884..26855)
                     /gene="ruvB"
                     /locus_tag="VVO77_001221"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEU5693237.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            27016..27108
                     /locus_tag="VVO77_001222"
     CDS             27016..27108
                     /locus_tag="VVO77_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEU5693238.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            complement(27923..28339)
                     /locus_tag="VVO77_001223"
                     /pseudo
     CDS             complement(27923..28339)
                     /locus_tag="VVO77_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(28351..29043)
                     /locus_tag="VVO77_001224"
                     /pseudo
     CDS             complement(28351..29043)
                     /locus_tag="VVO77_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144882.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(29343..31844)
                     /locus_tag="VVO77_001225"
     CDS             complement(29343..31844)
                     /locus_tag="VVO77_001225"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEU5693239.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDTSKPKFYALDMFPYPS
                     GVGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLVRTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVACLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDISREEL
                     QEIALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK"
BASE COUNT         9316 a         7536 c         6106 g         9114 t
ORIGIN      
        1 ttgagtatta aactaaatta aataatatta gcgcggagaa tttctaattc ttccttggtc
       61 aagcgacgcc attcccctcg ttccaggttc tcatctaata ctaaagttcc catagtcaat
      121 cgttgcaagt ccaccacttc cttgccacag tagcccacca tacgcttgat ctgatgaaac
      181 ttcccttctg caatggtcac acggatttgg ctttgattct tttctgtatc tatggataca
      241 agctccagta tagcgggttt acaggtaaag tctttgagag gaataccctc agcaaatgtc
      301 tccacatctt cttgggtcat gattcccttg acttgtgcca gataagtctt gtccacatga
      361 cgcttgggcg aaagaagaac atgagccagc tgaccatcat tggtcaagag caaaagacca
      421 tgcgtgttaa tatccaagcg tcctactggg aaaacttcct tactccgcgc caagtcatcc
      481 aacaagtcca gaacggttct gtgcttggga tcctcagtcg ctgagataac tcctttgggc
      541 ttgttcatca tgtagtagac aaactcttca tactccaaca cttgcccatc aaagcgaatc
      601 tcatctattt tttcatcaat ctgcaattta gctgattttt cttttttacc atttacagtc
      661 acgcgcccag ccttgagcaa gtttttgacc tcagtccgac ttcccaccgc acaggcaact
      721 aaaaatttat ctaatctcat agaactatta tatcatatca aaaggaggct ggtacaatga
      781 ccaacctcct tttcgtttca tactcttcaa aaatctcttc aaaccgcgtc aacgtcgcct
      841 tgccgtatat atgttactga cttcgtcagt tctatctgca acctcaaaac agtgttttta
      901 gctgacttcg tcagttctat ctgcaacctc aaaacagtgt ttttagctga cttcgtcagt
      961 tctatctgca acctcaaagc agtgctttga gcaacctgcg gctagtttcc tagtttgctc
     1021 tttgattttc attgagtatc agatttagga aattaacttc ctcgtctcca aaaaatagct
     1081 aagacaatca tggcacctaa aacagctggg ataatagctg ttcctgataa aactggcccc
     1141 caagttccaa agagcaagtg acctagaaag gctccgatcc aaccgagaaa catttttcca
     1201 aaacatccca ttcgctctcc acgattggtc atagcacctg ctaaaaatcc cactaggaga
     1261 ccaacgaaca tacttcctaa catattatct ccttaatttg cccaattccc attacggaaa
     1321 agaggtaccc gcgttccatc ctcacgaata ccatcgatat ccatttggtt agaaccaatc
     1381 ataaagtcta cgtgaacatc tgaacggtta agccctgcag cttcaagctc ctcttcgctc
     1441 atctccgctc catcaacaag gctagtcgca taggctgcac cgatagccaa gtggtttgac
     1501 gcattttcat cgaaaagggt gttaaagaag gtaatgcctg actgagaaat tggacttgga
     1561 tctggtacca aggcacattc acccaaggca cgcgcacccg cattttcaaa gacaaggtct
     1621 ttcataacct gatcaccctt ctcagcagtg atatctacga tttgtccatc cttaaagatc
     1681 accttaatgc cttcaatgat atttccgttg tagctaagcg gttttgtaga agtgacataa
     1741 ccatctgcac gacggaagtc aggcgctgtg aagacctctt ctgtcggcat atttggcaag
     1801 aatccttcgc cctgtgcatt gacagcacca gctgattccc aaacgtggtt ctttggcaaa
     1861 ccaagtgtta aatctgttcc tggcgctgtg tagtgaaggg ctgaaaattg ctccttatta
     1921 agcatatcgg ccttgctctt gagaatggct gcatgctctt cccaggcctt aacaggatct
     1981 gcttcgtaga cacggcaagt tttgaagatt tggtcccaaa ggagatcgac tgcttcttcg
     2041 tcgctcgcag catttgggaa gactttctta gcccactcaa gtccagcagc ggctgctaca
     2101 gtccagctaa ccttgttaga ttgagttgcg attcgcattg gcttcatggc aagtcccata
     2161 gctttagcag aagctgaaag cttgtcagcg tccactccgt tcaaggcacc tggatcagat
     2221 gaacgaactc caagacggct agccttgttc tccaagagat agttcatctc agcaatcttg
     2281 tattctggca cattgtccaa acgctccatc ggggcatgga ggaatttctc acggttaatc
     2341 acatcatctg tccactgaac gatgacctca tgcgcaccca aggcataagc ttctttcacg
     2401 attagatgtg ccaattcacg ttgctccaca tcaatagaga gagccaaagt gtgaccaggt
     2461 tgcacgttaa ttccgttcgc aaccaacaat ttcgcatatt tttctagatt ttctttaaaa
     2521 tttggtaaaa ccatcctgtt ttctcttttc tatttttatt tttctttcaa agcagaaaag
     2581 attcctgcta aagcaatagc acctgacaag agtgctgtcg ataaaagaat tgtacgatca
     2641 gcaagttcta attgatattc aaataccttc ttagccggct tatcttccgc aaatattctt
     2701 agtttcatga gaaccccctt aaaatagatt aaaataaatc actgtgactg cctgtcctca
     2761 gcaaatttaa aatcaattcc gacttatcta ctttataaac caaaagccaa tctggctggg
     2821 tatggcattc acgaactcct tgaaaatgct tggatgccgt caatgaatga tcacgatatc
     2881 tggcaggatg ttctttttct tgaaccagaa aattcaaaac ttcttctaat aattctgcct
     2941 tcaaaccacg cttcatagcc aacttaaaat cttttttaaa ctgtttatga taacgaatct
     3001 taagcacgta agtcctccat caaatctgag actgattcaa aagactggct catattacga
     3061 ttttggtcta aatccgttaa cacttggagc aacttccgat tttcgtctag tctaacatca
     3121 aaaggtaatc cctgatattg aattgcctga cgaaggaaaa tattaatagc tgttgtcata
     3181 tccattccca gattactaaa cacctgttgg gcctgctcct taacctcact atccagacgg
     3241 atgctcatac tcatctttga catactctca ccctctttcc atagactatt ttaacaaaaa
     3301 agaaagctaa tgtaaatcta ttggatatac gttagcctct tctaatagat tattaagcaa
     3361 ttttttaaaa caactcatca aacaaactca actggttatc ctctggcata tttccaagaa
     3421 tacccatctc atccatcttt tcaaccaagg ttgatgagag tccaccacgc ttgcgtagtt
     3481 ctgttttaga gaggaattct ccctcttcac gcgcccgcac cagttgcttg gcaacgttct
     3541 ctcccagacc atccattgct acaaatggtg ggataagggt atccccgtcg atgaggaact
     3601 ctgtcgcctg actacggtag agatctaatt tgccaaactt gaaacctcgt tcccacatct
     3661 cattgacaat ctcaagagtt gtatagagat cgatttccac attagaggct tcattgttct
     3721 tccgtttttc agagatttct tccattctgc gcttgatggc ctccaagccc gcacccatgg
     3781 tcttgatatc aaaagcctta gcacgaatgg agaagtaagc acagtagtaa taaataggat
     3841 ggtgaacctt gaagtaagct acacgcaagg ccatcataac gtaggctgcc gcatgggcct
     3901 tagggaacat gtacttaatt ttcccacagg attcgatata ccactctggc accttattag
     3961 ccttcatggc ttcgatatag ccatttctct cctcttctga aatctttagc cacaaaccct
     4021 tacgtacccg ttccataatg gtaaaggcca tcttaggttc cagacccgca tgcatgaggt
     4081 aaaccatgat gtcgtcccga caaccgataa cagtcgatag gtccgctatt ccttgcttaa
     4141 tcagatcctg agcattcccc aaccaaacgt cagtaccgtg ggacagacca gacagctgaa
     4201 gcaattccgc aaaggttgtc ggatgggttt cgtctaccat tccacgtacg aaatttgttc
     4261 caaactctgg aatccccaac atacccgtag gcgttccaat ttgttcaggt gttaccccta
     4321 gcacatcagt cccagaaaag agtgccatca cgccttcgtc atccatagga atttcattag
     4381 ggtcaatacc agacaaatcc tgaagttttc gaatcatggt cggatcatca tgtcccagta
     4441 catcgagttt gaggacgttc tcatcgatat cgtggaagtt aaagtgagtg gtctgccatt
     4501 cagccgtgac atcatctgct ggatactgga caggcgtaaa atcgtagaca tccatgtagt
     4561 tcggaataac aacgattccc cccgggtgtt ggcctgttgt ccgcttgaca cccgccgctc
     4621 cttgagcgag gcgttctact tctgcatcac gataaaactt gccataatct cgctcgtaac
     4681 ccttgacaaa tccataggca gtcttggcag ctaccgtacc aaccgttccc gcacggaagg
     4741 catattcttc accaaagata tcacgcacat ccaagtgggc gctaggctga tcttctcccg
     4801 agaagttcaa gtcaatatca ggaaccttat ccccatcaaa gccaaggaag gtctcaaacg
     4861 gaatatcctg tccgttttta ctgagtttgt gaccacagtt tggacagtcc ttatggggca
     4921 tatcaaatcc tgaaccgtac gaaccatctg tgataaactc actgtactga cactgaccac
     4981 agacatagtg aggagagaga ggattgacct ccgtaatccc aatcatggtc gcaacgaaac
     5041 tagatccgac agacccacga gaaccaacca aataaccccg ttcattagaa cgttgcacca
     5101 gcatctgcga tgccagataa atcacagcaa atccattccc cagtatggat gttaattctt
     5161 tttcaatccg caaatcaaca atatctggca gcggatttcc ataaatctca aaagctttct
     5221 tataggtcaa ctcagcaact gtttcttcag ccttgtcgat gaaaggcgta tacaagtcac
     5281 ccttaacgac ttcaacgggt tcaaatattt ctgccaaggc attagtgttt tcaataacca
     5341 gtttacgagc cagttcctct cccaaaaagg caaattcatc caacatctca ttagtcgttc
     5401 gaaaatgagc ctttggaagt ggtgctggtt gggcatgttc accatgaccg atagttcgat
     5461 taatcatcgc accctgtccc aaactacgga caataatttc acgataaatc tcttcttccg
     5521 gttcgatata gtgaacattt cccgtagcca gaacaggctt gccaaggcga tctccaacct
     5581 ctatcaaact cttgataatg gtctggagtt cctccatatc cttgacctgc tctttggcaa
     5641 tcaagggcgc atagatagcc ggtggcatga cctcgataaa gtcataatac ttggccacct
     5701 caaccgcccc atccacacct tgagaaacga ccacgtcaaa aacttcaccc tctgaacagg
     5761 ctgaacctaa aatcaagccc tctcgatggg catctagaac cgttctcgga atccgtggca
     5821 ctccttcaaa atacttggta ttagacaagg aaaccagctt aaagatattt tttagaccta
     5881 cctgattctt gacatagatg gtcgcatgct tgatccgagc ttttttgtaa gaatctggac
     5941 tgattagatc aatgttgagt ctagctaaat cggtcacacc atgtttttct gctacctctt
     6001 tgataaagat gaaaagcaga cgaccagtcg cttccgcatc gtaattggcc atgtggtgat
     6061 gttccaaggc cacaccaaaa cgcttggtca aaggccccaa accatggcgt ttatactcag
     6121 gatagaggtt tctagcaaac tccagcgtat caataactgg ctgactaatc tttggaagac
     6181 catgacgctc ataattagca ttcataaagc caacgtcaaa ggtagcattg tgggcaacta
     6241 ggaccgtatc cttgcaaaat tcttggaatt cttgcaaaac ttgttctagt ggtttggcat
     6301 ttttgacatg atcatctgta attccagtta actctgtagt aaaggctgac aagggatgcc
     6361 caggattgat aaattcatca aattcagcaa taacattccc cttgtacatc ttagaggccg
     6421 caacctgaat caagtcatta tagatagctg aaagtcccgt cgtttccacg tcaaagacca
     6481 cgtaggttgc ttctgacaag tccatctcca cttcgttata gacgataggg acacggtcct
     6541 ccacgatatt ggcttccatc ccatagatca gctggattcc cgctttctta gccgccttat
     6601 agccatgtgg aaaggactgg acattcccat ggtccgtgat agcaaccgcc ttgtgtcccc
     6661 acttagcagc tgttgcaaca atctcttcga cctctggcaa agcatccata gtcgacatgt
     6721 tagtatgagc atgaaactca acccgacgct caccttctgg catcaaatcc ttccgctcat
     6781 agtgaacaac ttcctgcaga tcctgtacgt tcatagtcaa atcgcgtgtg aagttattca
     6841 tctccacatt ccctcgaact cggagccaag aattcttctt gatgagatca aacttctggg
     6901 cctcttcctc gtttttaacc cacttttgca tagaaaaact tgaagtgtag tccgtcattt
     6961 taaagttgat taaaacacga cctgttctag tcactttttg ctccacatca aaaacaaccc
     7021 cttcaaatac cagacgattt tcctctgtcg tcacttcgat cataggagta atctccgcct
     7081 tatccagctt gggtttagct gcagcttttt tcgcttgaaa atcaaagact ggtttctctt
     7141 ccgctggagg aggtgccatc tgctccagtt gttccatagc acggagcgct tcctcattgg
     7201 cagcttgaac aatctgctca ttttcagcat gaaaggcctc ttcctgctct tgggtcagga
     7261 catcattctt atcgacttga cagttaaaag ttggaaaacc aaacttttca agttgtttgg
     7321 ctaaattagg aagatgattc ttcttaaaat gttccttatc aatcgcctca gatccttcaa
     7381 taaatagctg attaccctca gcacgaactt gcaaattttg ataaagggac ttaaaacctt
     7441 gactagcaca tggaccttca gagaaagcct ccctatagta ggactgcaag agctgatttg
     7501 aaaattcttg agaccgagcc ttaatttcaa aaacagcttt attgcctgtc ttagaaaatt
     7561 cttcgctcaa acctttcttt aattctaaaa agatttcaat cggtaaaata ttagaaaata
     7621 cgaaatgaaa ctcccatacc ttactaattt tatgaaccac aactcgctca atattggcct
     7681 gtgctaaagc aggagcctgt ctcatttcag caggcatccc caattgattc atcaaaattt
     7741 caaaactatt tgacattcat tttcctcaca ttattcttct actattttac catatttaga
     7801 ggtattttct aaagacaaaa ggaagccact aagtgacttc cttctagagt gaggacggat
     7861 tagtcttcac ctttattttt cttaataatt tcttcttgta ctgacttagg tacatcttcg
     7921 tagtggtcaa ataccatcat gaatgtacca cgtccttgag atgcagaacg aagaactgtt
     7981 gcgtaaccga acatttcagc aagtggaacg taagcacgaa cgatttggct gttaccgtgt
     8041 gcttccatac catctacacg tccacgacga gcagttacgt gacccataac atcaccaagg
     8101 ttttcttctg gaacagtgat tgttacaagc atcattggtt caaggatagc tggttgtgct
     8161 gatttagcag cttctttaag ggaaagtgaa gccgcaatct tgaaggcagt ttcagatgag
     8221 tcgacatcgt gatatgaacc atcataaagc ttagctttaa cgtcaaccat tgggtaacct
     8281 gcaagaacac cgttagccat agattctacc aaaccttttt caaccgctgg gataaattca
     8341 cgaggaacca caccaccgac gattgcgttt tcgaattcga atcctttacc ttcttcgttt
     8401 ggagtaaatt caatccacac atcaccgaat tgacctttac caccagactg acgtttgaag
     8461 aatccacgtg cttgagtaga agcgcggaat gtttcacggt aagatacttg aggcgcacct
     8521 acgttcgctt caactttgaa ctcacgacgc atacgatcaa caaggacgtc aaggtgaagt
     8581 tcacccatac ctgagataac tgtttcacca gtttcaacgt ttgtttcaac gcggaatgtt
     8641 ggatcttctt cagccaattt ttgaagggcg atacccatct tgtcttggtc agctttagat
     8701 tttggctcaa ccatcaattg gataactggt tctggaacgt tgattgactc aaggatgatt
     8761 ttagattttt catctgtcaa tgagtcacca gttgtagtat ctttcaaacc aacggcagca
     8821 gcgatatcac ctgagtaaac agtgtcgatt tcttgacggc tgttagcgtg catttgaagg
     8881 atacgtccga tacgttcacg tttaccttta gaagtattca atacgtatga acctgattga
     8941 agaacacctg agtaaacacg gaagaatgtc aaacgaccta cgaatgggtc agtcatgatc
     9001 ttgaaggcaa gagctgcaaa tggctcttcg tcagatgctg gacgagtttc ttcagcgtct
     9061 gtatctgggt taataccttt gattgctggg atgtcaagtg gacttggaag gtagtcgata
     9121 accgcatcaa gcatcaattg aacacctttg tttttgaagg ctgaaccaca caatactggg
     9181 aagaattcaa cgttgatagt cgctttacgg ataccagctt tcaattcttc gttagtgatt
     9241 tcttcacctt cgaggtattt catcatcaat tcttcgtcag tttcagcaac tgcttcaatc
     9301 aatttttcac ggtattcttg agcttggtca aggtattcag ctgggatgtc ttcttcaagg
     9361 atatccgtac caaggtcgtt agtatagatt tcagctttca tcttgattaa gtcaatgata
     9421 ccacggaagt catcttcaga accgattggc aattggattg ggtgtgcatt tgcttgaagg
     9481 cgatcgtgaa gtgtgcttac agagtaaagg aagtcagcac cgattttgtc cattttgttg
     9541 gcaaatacga tacgtggaac tccgtactca gttgcttgac gccaaactgt ttcagtttga
     9601 ggctcaacac ctgattgtga gtcaagaacg gtaaccgcac catccaatac acgaagagaa
     9661 cgttgtactt cgattgtgaa gtccacgtgt cctggtgtgt cgatgatgtt tacgcggtgg
     9721 ttgttccatt gagctgttgt cgcagcagat gtgatcgtga taccacgttc ttgctcttgc
     9781 tccatccagt ccatttgtga cgcaccttcg tgagtttcac cgattttgtg gattttacca
     9841 gtgtagtaaa gaatacgctc agtagttgtt gttttaccgg catcgacgtg agccatgata
     9901 ccgatattac gagttttttc aagtgaaaat tcgcgtgcca tgaggtttgt ttctcctatt
     9961 tatttttgat ttctattcta ttataacacg attttaataa aaacggatag gcaggaccta
    10021 cccgttctca atgttttcat gctattgttg gtttcaactt acgagatggt aagctgagtt
    10081 atagctaata ctaatcgatt tagctaattt gaacccgggc taaagttagt tagccgatgt
    10141 gagctggaac gggatgctgc gtgaaaaaga taaaactcct tgtattcgtc gaatactgcg
    10201 tcagtttcct attttcacct tgcatcctta ccgttcctag catcatgatt tagttgagct
    10261 caagctaaaa gtctggagaa aaagatgaat ctcattggtt gcaaccgcaa cctgcttcga
    10321 ttccctattt tctctgggac tttcttaacg ctttcgcatc ctatcttacc aacggaagtg
    10381 tgcgaatgca cggttagctt cagccatacg gtgagtatct tcacgtttct taactgctgc
    10441 accagtgttg ttagcagcat ccaagatttc ttttgcaaga cggtcttgca ttgtgtgttc
    10501 accacgaaga cgagcgattg ttaccaacca acgaagtcca agtgttgtac gacgttctgg
    10561 acgaacttca actgggactt ggtagttaga accaccaaca cgacgtgcac gtacttcaag
    10621 tacaggcatg atgttttcca tagctgtttc aaatacttca agtgcatcgt tgccagtagc
    10681 ttctttgatt tgctcaaaag caccgtaaac gattgaagca gcagtaccac gtttaccatc
    10741 aagcataacg cggttgataa gacgagtaac tagttgtgaa ttgtatagcg gatctggcaa
    10801 tacgtcacgt tttggagctc tatttttacg actcatttct ctttatcccc tttccttatg
    10861 cttttggacg tttagtaccg tatttagaac gaccttgttt acgatcgtta acacctgcag
    10921 tatcaagtgc accacggacg atatggtaac gtacccctgg aaggtctttt acacgtccac
    10981 cgcgaagaag caccacgctg tgctcttgca agttgtgtcc gatacctggg atgtaggcag
    11041 taacttcgat aaggttgctc aaacgtacac gagcgaattt acgaagggct gagttaggtt
    11101 ttttaggtgt cattgttcca acacgagttg caacaccacg tttttgtggt gaagaaacgt
    11161 ttgtttgaac ttttttatga ctattgtaac caacgttcaa agctggtgat ttagattttt
    11221 ctacttttga tttacgcggt ttgcgaacca attggttaat tgtaggcatc tacattctcc
    11281 tgtgtttttt tatttttggt gatgatacac ttggtgacag atatcatctg tgtgtacttt
    11341 tgcaacattt gtcagcacgt ccctgtacac tcttgagaga ccaaaagtaa aaagtaccgt
    11401 ctattattgt aacaaaattt tcccttgttt gtcaagatat ttttcttttt tattggtaat
    11461 gttagagatc aatttctgaa taaaaatagc tgggaacaca tcatcttcct aataatacgg
    11521 cttggcttat gtgacatttt tatctccgtc atttatactg atatataaaa tagtacagaa
    11581 aacttctcaa aagtaagaat ttttttcaca aatcaaagaa aacgcttgca tattgtttta
    11641 ctacatgcta tactgatata gaaatttatt gattggagaa tcattatgag aaaaacacca
    11701 tctcacactg agaaaaaaat ggtctacagc atccgttccc tcaaaaatgg aactggttct
    11761 gtccttatcg gcgcaagcct tgtcttgctt gccatggcta caccaactat ctcatccgac
    11821 gaaagtacac caaccactaa cgaacccaac aacagaaata caaccaccct tgcccaacct
    11881 cttactgata cagcagctgg ctctggtaag aacgaaagtg atatttcttc acctagaaat
    11941 gcaaacgctt ccctagagaa aacagaagaa aaacctgcaa cagagccaac tacttctact
    12001 agtccagtaa caactgaaac taaggcagaa gagcccatcg aagataacta cttccgtatc
    12061 catgtcaaaa aacttcctga agaaaacaag gatgctcaag gactatggac ttgggacgat
    12121 gttgaaaaac catctgaaaa ctggccaaac ggagctttgt ccttcaagga tgccaagaaa
    12181 gatgactacg gctattacct agatgtcaaa ttaaagggag aacaagccaa gaaaattagc
    12241 ttcctcatca acaatacagc tggaaaaaat ctaaccggcg ataaatctgt agaaaaacta
    12301 gttccaaaaa tgaacgaggc ttggttagac caagattaca aggttttctc ttacgagcca
    12361 cagcctgcag gaactgttcg cgtcaactac taccgcacag atggcaacta tgacaagaaa
    12421 tctctctggt actggggaga tgtgaaaaat ccaagtagcg ctcaatggcc tgacggaaca
    12481 gactttacgg ctacaggcaa atatggccgc tatatcgaca ttcctcttaa tgaagccgca
    12541 agagaatttg gatttttatt actagatgag agcaaacaag gagacgacgt gaaaatccgt
    12601 aaagaaaatt ataagttcac agatttgaaa aatcatagcc aaattttcct aaaagacgat
    12661 gatgaatcga tttacacaaa tccatactat gtccatgata tccgtatgac aggagcccaa
    12721 cacgtaggca cttctagcat tgaaagtagc ttttcaacac ttgtcggtgc taaaaaagaa
    12781 gatatcctca aacactccaa catcactaat cacctaggaa acaaggtaac tattaccgat
    12841 gttgcaatcg atgaagctgg taagaaagtg acctacagcg gagatttctc tgacacaaaa
    12901 catccttata ctgttagcta caattccgac caattcacta ccaaaacaag ctggcacctg
    12961 aaagatgaga catacagcta tgatggcaaa ctgggagctg acctaaaaga agaaggaaaa
    13021 caagttgatt tgaccctttg gtcaccaagt gctgataagg tttctgttgt tgtctacgac
    13081 aagaatgacc ctgacaaagt agttggaact gtcgctctcg aaaaagggga aagaggaact
    13141 tggaaacaaa ctctagacag cacaaacaaa ctcggaatca cagatttcac tggctactat
    13201 tatcaatacc aaatcgagcg tcaaggtaaa actgttcttg cactcgatcc ttacgctaaa
    13261 tctcttgctg cttggaatag cgacgatgcc aagattgacg atgcccataa agtggctaaa
    13321 gccgcctttg tagatccagc taaactcgga cctcaagact tgacttatgg taagattcac
    13381 aatttcaaga ctcgtgaaga cgccgttatc tacgaagctc atgtgcgtga cttcacttca
    13441 gatcctgcca ttgcaaaaga cttgaccaaa ccatttggga cttttgaagc cttcattgaa
    13501 aaactagact atctcaaaga cttgggtgta acccatatcc agctccttcc agtcttgtct
    13561 tactactttg tcaatgaatt gaaaaaccat gaacgcttgt ctgactatgc ttcaagcaac
    13621 agcaactaca actggggata tgaccctcaa aactacttct ccttgactgg tatgtactca
    13681 agcgatccta agaatccaga aaaacgaatc gcagaattta aaaacctcat caacgaaatc
    13741 cacaaacgtg gtatgggagc tatcctagat gtcgtttata accacacagc caaagtcgat
    13801 atctttgaag acctagagcc aaactactac cactttatgg atgccgatgg cacacctcga
    13861 actagctttg gtggtggacg cttggggaca acccaccata tgaccaaacg gctcctagtt
    13921 gactctatca aatacctagt tgatacctac aaagtggatg gcttccgctt cgatatgatg
    13981 ggagaccatg acgccgcttc tatcgaagaa gcttacaagg ctgcacgcgc cctcaatcca
    14041 aacctcatca tgcttggtga aggttggaga acctatgccg gtgatgaaaa catgcctact
    14101 aaagctgctg accaagattg gatgaaacat accgatactg tcgctgtctt ttcagatgac
    14161 atccgtaaca acctcaaatc tggttatcca aacgaaggtc aacctgcctt tatcacaggt
    14221 ggcaagcgtg atgtcaacac catctttaaa aatctcattg ctcaaccaac taactttgaa
    14281 gctgacagcc ctggagatgt catccaatac atagcagccc atgataactt gaccctcttt
    14341 gacatcattg cccagtctat caaaaaagac ccaagcaagg ctgagaacta tgctgaaatc
    14401 caccgtcgtt tacgacttgg aaatctcatg gtcttgacag ctcaaggaac tccatttatc
    14461 cactccggtc aggaatatgg acgtactaaa caattccgtg acccagccta caagactcca
    14521 gtagcagagg ataaggttcc aaacaaatct cacttgttgc gtgataagga cggcaaccca
    14581 tttgactatc cttacttcat ccatgattct tacgattcta gcgacgcagt caacaagttt
    14641 gactggacta aggctacaga tggtaaagct tatcctgaaa atgtcaagag ccgtgactat
    14701 atgaaaggtt tgattgccct tcgtcaatct acagatgcct tccgacttaa gagtctccaa
    14761 gatatcaaag accgtgtcca cctcatcact gtcccaggcc aaaatggtgt ggaaaaagag
    14821 gatgtagtga ttggctacca aatcactgct ccaaacggcg atatctacgc agtctttgtc
    14881 aatgcggatg aaaaagctcg cgaatttaat ttgggaactg cctttgcaca tctaagaaat
    14941 gcggaagttt tggcagatga aaaccaagca ggatcagtcg gaattgccaa cccgaaagga
    15001 cttgaatgga ctgaaaaagg cttgaaattg aatgccctta cagctactgt tcttcgagtc
    15061 tctcaaaatg gaactagcca tgagtcaact gcagaagaga aaccagactc aaccccttcc
    15121 aagcctgaac atcaaaatga agcttctcac cctgcacatc aagacctagc tccagaagct
    15181 agacctgatt ctactaaacc agatgccaaa gtagctgatg cggaaaataa acctagccaa
    15241 gctacagctg attcacaagc tgaacaacca gcacaagaag cacaagcatc atctgtaaaa
    15301 gaagcggttc gaaacgaatc ggtagaaaac tctagcaagg aaaatatacc tgcaacccca
    15361 gatagacaag ctgaacttcc aaatacagga atcaaaaacg aaaacaaact cctatttgca
    15421 ggaatcagcc tccttgcgct ccttggtctc ggtttcttac taaaaaataa aaaagagaac
    15481 taaactagcc ctcctataga aaaatccccc aagcattata gctcggggga ttaattttcg
    15541 tacaatattt gttgtcctaa taaacttgat taggattttt tattaagcct ctttcatagc
    15601 aaaataagct cgtacttttg gtgcaacttg tgttccgaag agttcaatag ctctcagaac
    15661 ctggtcatga ggcatagaac caagcggtat atgaagcatg aagcggtcca atcctaaatc
    15721 ctctatcatg cgaatcaatt tttcggccac ctgatctgga ttgccaacaa acatggcgcc
    15781 atttggccct acctgctcca aatattgctc ataacgcaat tcctgccagt gcggacggtc
    15841 tttggaaata gcatccacca cttgcttagt cggatggaaa taatctttca ccgcctgctc
    15901 accatcttcc gcaatccacc cccaagaatg ggctcccact ttcaagtctt tgtcagcatg
    15961 gcccgcttcg cttccaatct cacgataagc ctgaatcaac tttttaaaat aacgtggatt
    16021 accaccaata atagcatata caatcggtag accagcctga gcaatcttca ctgttgattc
    16081 gacatgacca cctgtagcta tccacaaggg caatttgtcc tgaactggac gaggataaac
    16141 ttctttacca gcaatcgttt gagtcaatcg accttgccag tctaacttgg tcttttcatt
    16201 gactaactga agcaagtcta atttctcatc aaaaagagag tcgtagtctt tcaagtcata
    16261 accaaacaga gggaaagatt ccgtgaaaga gccccttcca gccataatct ccgatcgtcc
    16321 atctgacaaa gcatcgatag tggcatactg ttggaacaaa cgaatcgggt ccatgcttga
    16381 cagaatgctg actgcactgg tcaaacggat tttcttggta ttgactgccc cagcggccag
    16441 gacaatctct ggggctgata ctgcaaaatc cgcccgatgg tgctcgccaa tcccatatac
    16501 gtccaaacca accttgtcag ccagctcaat ctctgccacc aactggcgaa tgcgttcagc
    16561 atgactgtaa gtttgtccag tcccttcaag ctccgttatt tccccaaatg ttgaaattcc
    16621 caattctacc attgtgattc tccttgtcta tctctgtact tcaatttgaa aaattattct
    16681 aatactcaat gaaaatcaaa gagcaaacta ggaagctagc cgcaggttgc tcaaaacagt
    16741 gttttgaggt tgtggataga actaacgaag tcagtaacca tacctacggc aaggcgacgt
    16801 tgacgtggtt tgaagagatt ttctaagagt ataacacgaa tcttgagtac aagcaaccaa
    16861 tttgctcaca agaaaaagcc tagataacta gactttttta gcttattcta ccgttactga
    16921 cttggcaagg ttacgtggtt tgtccacatc gaggccacgg tggagggttg caaagtaagc
    16981 gactaattgc gtcggtacga ccattgaaat tggtgagagg tatggatgta cggtcgtaag
    17041 gacgatatcg tcggtatctt tggctacatt ctcttctgcg atagtgagga ctttggcacc
    17101 acgggctgcg acctcttgga tatttccacg agtatggttg gcaagaactg gatctgacaa
    17161 gagagccaaa acaggcgttc cttcttcaat caaggcaatg gttccgtgct tgagttctcc
    17221 tgccgcaaaa ccttcacact ggatataaga aatctctttg agtttgagac ttgcttccat
    17281 ggctacgtag taatcttgac cacgtccgat gtaaaaggcg ttacgagttg tttcaagaag
    17341 ttcacgaacc ttggcttcaa tggtttcttt ctctgaaaga gttgattcga tagactgagc
    17401 tacgattgac aattcatgaa ccaggtcaaa ggcttgcgct ttagcattac catttgcttc
    17461 tccgactgct tttgcaagga aggcaagggc tgcgatttgc gctgtatagg ctttagttga
    17521 tgccacggca atttcaggac ctgcgtgaag gagcatggta tagttggctt cacgtgagag
    17581 ggttgaacct ggaacgtttg tcactgttaa gcttggaatt cccatttcat tagccttgac
    17641 caaaacttga cgactatccg ctgtttcacc agattggctg ataaagatga agagtggttt
    17701 cttgctgaga agtggcatac cgtagcccca ctcagatgag attccaagtt caactggtgt
    17761 atctgtcaat tcttccaaca ttttcttaga agcaaatcct gcatggtaag atgttccagc
    17821 tgcaaggatg tagatgcggt ctgcgtcttg aacagcctta atgatatctg ggtctacgac
    17881 aacttgacca gcctcatctg tgtaggcttg gatgagtttc cgcataacag ttggttgctc
    17941 gtcaatttcc ttgagcatat agtaagggta agttccctta ccgatatctg acaagtcaag
    18001 ttcagcagtg tagctagcac gctcacgacg atttccatca tagtcttgaa cttccacact
    18061 atcagccttg acgattacca actcttggtc atggatttcc atgtattggt tagtttcacg
    18121 aatcatagcc atggcgtctg agcagaccat gttatagcct tctccaagac caatcaaaag
    18181 tggtgattta tttttagcta cgtagatgac ttcaggatct tgtgagtcaa ccaaggcaaa
    18241 ggcataagaa ccacggatga tgtgaagggc ttttttgaag gcttcaagaa ctgagagccc
    18301 ttcttcttcc gcaaattttc caatcaaatg aacggctatt tcagtatctg tctgcccctt
    18361 gaagtggtga cctgcaaggt attcttcctt gatttcaaag tagttctcaa tcaccccatt
    18421 atgcaccaag acaaaacgtt ctgtctcaga gcggtgtggg tgagcattgt cctcagttgg
    18481 ttttccgtga gtagcccaac gagtatgtcc gataccagtt gttccctcaa caccagctgt
    18541 cttggcagac aattctgcaa tacgaccaac agccttcacc aaatggttat cagcaccatc
    18601 taggacaaaa attcccgcag aatcatagcc acggtattca agcttttcaa gcccttgaat
    18661 caaaatatca gttgcatttg tgtttccaac aacaccaaca attccacaca tagtatatac
    18721 gacacaggca agctgtgctt tctccttaaa attggtatag tctaattcat cttttataga
    18781 atcagcaaaa acagtatata cttgtttctt tcacttgtca agagtaaaaa ttggtatagt
    18841 tcaaattaag ctcctgtaag cataaaaact ctgaccgatt gggataatca gtcagagtcc
    18901 tttttaaaat ccattattat cgcttaattc tttgaaccag tggcctgatt tcttcagacg
    18961 acgttcttgc gtttccaagt ctaattcgac caaaccatag cgatttttat agctgttgag
    19021 ccatgaccag cagtcaataa aggtccaaat caagtagccc ttacagttgg caccatcttc
    19081 aatggcacgg tgaagttcac gaagatgacc ttttacaaag tcaatacggt aatcatcttg
    19141 aatcattcca tcttgacgga atttttcttc cccttcaaca cccataccat tctcagtcaa
    19201 catccactca atattgccat aattttcctt gatattttgg gcgatgtcat aaatcccttg
    19261 ctcataaatc tcccaaccac ggtgagaatt gattttacgt ccaggcatca cataaggctc
    19321 gtaaaaatgt tctggtaaga gtggactatc tggatgctta gcaaatcgag gagccataac
    19381 acgcaaaggt tgatagtagt tcacaccaag gaagtccacc gtattatcac gaatgagttc
    19441 caactcttcc tctgtagcat caggtaaaag accgtgttca tgcaagattt ctaccaactc
    19501 ctgtggataa gtccccaaga cagatggatc taagaaagat tgggcctgaa aaagggccgc
    19561 aatacgagct gccttgacat cagcaggatg ctggctacgt ggataagccg gtgtcaagtt
    19621 gaggacaatc ccaatcttgg aatcaggcaa aagttcatgg caagccttaa cagcccggct
    19681 gctggccaat tgtgtatgat aggctacctt aacagctgcc tctgcatcca ccttatgtgg
    19741 ataatgggca tcataaaaat aaccaaattc tacaggaacg atgggctcgt taaaggtaat
    19801 ccattgatcc actaaatctc cataagtctc aaaacaaaaa cgagcatagt cttcataggc
    19861 tgagactgtc gccttatttt cccaaccatc accatcctct tgaagggcaa aaggtaaatc
    19921 aaaatgatag agattgacta acagacgaat tcctttagcc ttaatagcct caaagacctt
    19981 acgataaaaa tccacacctt gagggttgac tttcccacag ccttgtggaa aaatccgtga
    20041 ccactgaata gaagtccgaa agactgtgtg accagtctct aacaaaagct caatatcccg
    20101 ctcccaattt tcataaaaag tcgatgtctt atctgaacca atcccattat agtaacgatt
    20161 tggctccact tggaaccagt aatcccagag attgtctccc ttaccgtcac cagctacacg
    20221 tccttctgtc tgcggtccag aagtagagga tccccagaca aaatcctttg gaaatcttag
    20281 cataacattt acctctttat ctactcattt ctcccattat acagaaaaaa caaggtaaaa
    20341 actagttaca ttttttcctt gtttttcttc tgattatagt ttttatttct tgcttaggat
    20401 ttcaagcgtt tcaagcacgt tatctgcatg aacctcaatg gtgtcaccag ttgccttgat
    20461 cttaacttct acaatgccat cggccgcttt tttaccaaca gtgatacgga ttggaagacc
    20521 aatcaagtca ctatcgctaa atttaacacc gacacgttcg ttacggtcat ctgtcaagac
    20581 ttcataacca gctcccatca agcttgcttc aagtttttct gtcaaggctt gcgcttcttc
    20641 atccttgaca ttaacagtaa tcaaatgcac atcaaatggt gccaattctt tagggaaatt
    20701 gattccccaa gcgtaacggt attcaccttt tggcgttttg ttaacaaaga ggcgagcgtg
    20761 ttgctccatc actgctgaaa gaagacggct gacaccgata ccgtaacatc ccatgatgat
    20821 tggcacagca cgaccatttt catccaagac atctgctccc atgcttgctg aatagcgagt
    20881 tccgagtttg aaaatatgac cgatctcaat accacgcgca aagttaagga caccttgtcc
    20941 atctggggaa atttcaccct cacgaacttc acggatatcc acatattctg cagtaaaatc
    21001 acggcctggg ttcacaccag tcaagtggta gccatcttcg ttagcaccga caactgcatt
    21061 gcgaacatct tgcaccttac gatctgcaat aattttaata ttctctggca aaccaactgg
    21121 tccaagtgaa ccaaatcctg cttgaacaac attcgccact tcttcttcgc tagcaacgtc
    21181 aaagaaatct gctcccaagt gatttttcaa cttgacttcg ttgagttggt catttccaac
    21241 tagaagggct gcaacaagct caccatctgc aatgtagaag agggttttaa tcgtttgttc
    21301 ttctggaaca ttgaggaaag ctgcaacttc atcaattgat ttaacatctg gcgttgcaac
    21361 acgagtaact tcttcttcag cgacaacacg gttgcttggt ttgtactcgt ttgttgccat
    21421 ttctaagtta gctgcatagc tagactcact tgagtaagca atggtatctt caccagagac
    21481 tatccatttg agcaattctg ccttgatttc ttcttgcact tctgcaggaa tttcgtcaaa
    21541 tgaggcaact gacttgtcca agacaaccca gcggtcaagg tctgtacgag cagatgtaat
    21601 ggccataaat tcttggctat ccttaccacc catggctcca ccgtcaccaa taatagcctt
    21661 gaagtctaaa ccactacgag tgaaaatacg ctcataagct gctttgtact catcataaac
    21721 actatccaaa ctatcatagt tagcgtggaa actataagca tccttcatga taaactcacg
    21781 tgtacgaaga agtccattac gcgggcgttt ttcatcacga tacttgggct gaatttgata
    21841 aaggttgagt ggcaattgct tgtaagattt aacagaatca cggacaatag ctgtaaaggt
    21901 ttcttcgtga gttggaccta agataaagtc tgatttttca cggtttttta gtttgtaaag
    21961 gtcttcacca taggtttcgt aacgacctga ttcacgccac aattctgcac taagaagggc
    22021 tggagccaac atctcaacag caccaatctt ttcgaattct tggcgcatga tgtttttagc
    22081 tttttcaatc acacggttgg caagtggtag ataagaataa acacctgctg aaacttggcg
    22141 aacataacca gcacgcaaca taagagcatg gctgataact tgagcatcgc ttggcatttc
    22201 gcgaagcgtt gggataggca ttttactttg tttcataata ttcctcgatt atctaaaaaa
    22261 gagtcgcata atgtcattcc aagtcacagc aatcatcaag acaaccatga tgaccactcc
    22321 ggccaaggtg acataggttt caatttcttg tttcaatggt ttgcggcgga tggcttctag
    22381 gatattgagc acaatcttac caccatccaa ggctggaatc ggaataagat taaaaatccc
    22441 aatattgatg gaaatcattg ccaagaagta caagatattt tcaattccat ttttagcagc
    22501 atcactactt gccttaaaga tagcaacagg tccacccaac ttgttcaaat ctggttggaa
    22561 aatcagattt ttcagagctg agagaattcg gagagctgag tcagcagcag ttgtaaaacc
    22621 acctacaaac atggatagaa aatctgactt accccccggt tgaacaccta gaaggtaacg
    22681 accttgacta tctttgggtg taacagtgac ttgtttgtca ctcccctttt cagaaatagt
    22741 cacatccaaa gtcggtgccg tcttatcttt ggtttctgtt tccacagctt ggatcaagct
    22801 ttcccagttg ctaacctcat gtgagccaat cttggtaatt tgtgccgttt ctggtactcc
    22861 taccttggcc aaggcacctt ggggcatgat atggaactga ttggtatcaa catctctgac
    22921 accaccctgc ataaagatta aaacccaaaa aacaacgaca cctaagataa aattgttcat
    22981 aggacctgca aaattggtaa tcagtttgcc ccagatagtc gcattttgat attgaacatc
    23041 taaaggtgca atccgaacct cagtaccatc tgcttccaca accgttgcat cgtgatccac
    23101 tgcaaatgtt ttttcttctt ccagaaccaa tcctttgata aagagcttgt cttcaaaatc
    23161 aaactgggtc acctgcatag ggaggactgt ttgatccaat tttttacctg agagattgat
    23221 gcgtttaacc ttaccatcat cagcaagtgt caaactaaca ggcgttcctg tcttgatttc
    23281 agttgtatca tcaccccaac cggccatgcg gacatagcca cccagaggca agattcgaat
    23341 ggtataggcc gttccatcct tgccaatgtg agcaaaaatt ttaggtccca taccgatggc
    23401 aaattcacgt actaaaatcc ctgatttctt ggcaaagtag aagtgcccga actcgtgcac
    23461 cactacaata atcccaaaaa ctagaataaa ggttaaaatt ccaagcatag tgtttcctcc
    23521 gtcttttgat taaaagagtc caaataagtg catgattgga aatacaagca acatactatc
    23581 gaaacgatcc aaaacaccac catgtccagg gataaatttc ccagaatcct taacaccaaa
    23641 atgacgtttg atcgaacttt ctagtaaatc accaaattgt ccagcaatgc taaagaaaat
    23701 agcaaagact gacatcttgt aaattccata tggaagagca actgtactgt caactatcat
    23761 aaagataatg gttactaaaa ttgctcctaa aataccaccc aaggcaccct caagggtttt
    23821 attaggcgat acccttggtg ctaactttcg tttcccatag ttcatcccaa caagataggc
    23881 accactgtct gtcgcccaga cgatacacaa ggctaagaga gccttgtcca aacctgcaac
    23941 acgagcatct agtaaagcat taaatccaaa gcccacgtag aagctcatag caagagggaa
    24001 aaccgcatcc tcaatcgtat aagacttgct aaaaacggtc gttcctaaca tgattgaaat
    24061 caaaacacta taggcaacca cattcccatc aactggcaaa aaagtcaggt aattctccaa
    24121 gggaatggtc aatgcaaagg ttgcaaagag ggtcaagagg ccctccatcg tcatggtctc
    24181 tagacctctc atcttcaaaa gttcatgcat ggctagcatg gctatgattc cgattgctat
    24241 ctgaagcaag aggcccccaa tcattaaaat tggtaggaaa atagccaggg caatccctgc
    24301 aaacaaggtt cttttctgta aatcctgggt catatttcct cctaaactcc tccaaatcgg
    24361 cgatgacgac gattataggc aagaatagct tcctgcaagg ccgcttcgtc aaaatcaggc
    24421 cataaggtgt ccgtaaaata aagctcacta taggctccct gccatggaag gaaattgctc
    24481 aaacgtaatt ctccactagt acggataatc aagtctgggt ctcgtaagtc cttaggcaaa
    24541 tgctgagtaa agagatagtt accaatcaat tcctctgtga tgtcacctgg gttgattttg
    24601 gcatctaaaa catcctggga aatcaactta agcgcctgtg taatctcagc acgtccacca
    24661 tagttaagag caaaattaag aatcaatcct gtgttgttct tagtcaattc ctcagccttg
    24721 gttaaagctt caaaggtttg cttaggcagg cggtctgtct ccccaatcat ttgaatctta
    24781 acattattcg catgtagttc cgggacataa ttatcataaa actctactgg caagttcatg
    24841 ataaacttga cttcctgatc tggacgggtc cagttttccg tagaaaaagc atagaccgta
    24901 ataaccttga cgcccagttt gttggctgcc ttggtcacgg tttgcaatgc ttccatgccc
    24961 gccttatgtc caaaaactcg cggttgcata cgttttttag cccaacggcc attgccatcc
    25021 atgatgatgc cgatatgagc aggaacctgt gtcggaacct ctacttccac agccttatct
    25081 ttcttaaaaa atccaaacat gatcttattc ctattcaaaa atctatcgtt tcattatacc
    25141 atatttcccc attttcttct atcactaagc tatttattct caggcaccat gcccattttt
    25201 caaaaaaata agccgcctga ttgggcgact ttatttttat agggagatta ttatgaaaaa
    25261 gttttaggag tttaagttaa ggtcttctta acttatgaac ttagtgtaca ctccctagct
    25321 taaagtttcc ttaagtattt ttaaaaatca aatttttcca tttctcctgc caatttttct
    25381 tggataaacg tgtttgatag agttccattc ggtcttcatt ttctaagaaa tgaggagttg
    25441 gacgaacttg aaaattcaaa atatcctcca aaccataagg tgcatagagt tcaaaatctg
    25501 attcttcatt caagcgcagt ccaactgccg tacaccgttc tggatactta ctcatagcat
    25561 cacgagaact ggtataggaa gcagtgtgag gactgtgctg gtgcatatag acctgatttt
    25621 tcaattccca ctggtactga ggaaaatcct ctctcagctt tttctccagt aataaggttt
    25681 cctcataaga aaaatctgga tcaaagaaaa tcacatctat atctgtttca tgatcaaaag
    25741 gggatttgtc tgacaaaaga ttccagatga aatttctgac agaacctgct gccaactacg
    25801 agtctttcaa accaaggtct cggatgatcg tcagaatggc catcatatct ggattttctc
    25861 taaaagcctc taagatttct tgcttatttt tcactgtatt cataacctaa gtgctcatat
    25921 gccttagcag tcgccacccg tccagaccgt gtccgcatga taaaaccttt ttgaatcaag
    25981 taaggctcat acatgtcttc aactgtctca cgctcttcgg cgatattgac agaaagagtt
    26041 cctagaccaa caggtcctcc actgtacatc tcaatcatgg tacgaaggat tttttgatcc
    26101 acatagtcca aaccttcatg gtcaacatcc agcatagtca aagccttatc ggtaataata
    26161 tcatcgatta ccccattccc cattatctgg gcaaaatcgc gcacgcgctt gaggagacga
    26221 ttggcaatac gaggggttcc acgactacgt agggccaact cagatgctgc ctcatgagtg
    26281 atttccatct caaaaatatc tgccgtccgc tcgacaattt ctgtcaagtc agcatgggca
    26341 taatactcca tatgacctgt aatcccaaaa cgtgcccgta gtggatttga gagcatacca
    26401 gcccgagtcg tcgcaccaat caaggtaaaa ggaggcaact ccaaatgaac actgcgactg
    26461 ccttcaccag ccccaatcat aatatcgatg tagaagtcct ccatggcact ataaagcact
    26521 tcttccactg acatgggtaa gcgatgaatc tcgtcaataa agaggacatc tccaggctct
    26581 aactcattca aaatcgctac caaatcaccc gctttttcga taacaggacc agacgtttgc
    26641 ttgagattga ctcccagttc attggcaatg acaaaagcca tggttgtttt cccaagccct
    26701 ggagggccaa ataagagcac atgatccagc gcttcatccc gcattttagc ggcttcgata
    26761 aagatctgaa gctgatcctt aaccttatcc tgaccaatat attcacgtaa atactgagga
    26821 cggagcgtgc gttctactaa ctcctcatca cccatcatct cattatctaa aattctactc
    26881 atggctctat tatatcaaaa aaacaagcca caaacaaaaa agccacctga ttgggtgact
    26941 cctaagttta gcacttatgt ggtataatat tatacggcac ttctacaccg cctacgaaag
    27001 gaggtgagat agcccatgat ggaattagta ctcaaaacta tcatcggacc aattgtggtc
    27061 ggtgtcgttc ttcgtatagt cgataaatgg ctaaacaagg acaaatagtg tcaaaaaaga
    27121 cctcaagctt atttggtcgt gagcttgggg tcttttctag cctatgatat agaactagta
    27181 ctcaattcct ttttattatc ccatagttca cgaattttgt caaaggttta cattttcttc
    27241 aaccgctgta cgacaagacg gttaagatta agagaacgtt agggattcta tcaatttcat
    27301 agaaattttg atttcgtaaa cgaagagaca atcttacatg tcacttctca tttaatacgc
    27361 cactactaga caagcaaaat cattattaca gtagttccag ttcttcaatt aacagtcact
    27421 tacaatcaaa ttgagtttga actagctgaa gcgaccacag acctatttct tagttatatt
    27481 cgctaaaaaa gtccccgcca attccccgac caaaatccga aaaataccga aaaatatcga
    27541 aaaattattt ttagaatagt ccccaaaagc ctgaaataga gctaaaaaac tccacctgat
    27601 tgggtggagt taagggagat tattatgaaa aagaaaagtt taggatttta ttaaataaag
    27661 ttaggaggtc tttatttaat aactacatga tacaagacga aacttaaaac tagcttaact
    27721 tttctaaaat tttactattt tgcaaaaaat ttctatcacc agcacctcac cacgcaaaaa
    27781 agccacctga ttgggtggct tcattaggag attgtgatga aaaaagttta ggattttatt
    27841 aaataaagtt aggaggtctt tatttaatga ttatataata ctagaccatc cttaaatttt
    27901 gcttaagaaa aaacaagttt tgttattttt tacgattcat ccaagtcatc cctatccaat
    27961 tataggtgga taagatttca aagcccatag aacgattaaa tcccacgttt ttttctgtct
    28021 gttctgtcgc cagctggact tgataggcct ctttaaaatt tcctaaagcc tgtttcatca
    28081 aggagctacc aatcccttgg cgctgatagc tagacaaaac aatcaaatcc tgtacaaaaa
    28141 ctgatgaaaa accatctcca accaaacgaa tcaagcccac aacagcatca ccatcaagtg
    28201 ccagataaat tattaatgaa tgatacaagg tctactccag catctgaggt tgatttgtat
    28261 aatttgtcca accgacagcc tgatagagat gcaaaacatc ctcgaacttg acgatttctt
    28321 gctttctaat agtgatcatg tcaacacctc ttaaaactct ctcaagctct tgtactgctg
    28381 tccattttta tcaaaatttt caggacgcaa ccatgtttcc aaacgatctt tgactttggg
    28441 ccagtcctta tcaatcatag acaaccaatc catatctctc gtacgcccct tataaaccac
    28501 tgcctgacgg aaggttcctt cataaataaa gcccaaacgc tccgcagcac gtctggatgg
    28561 caggttaaga gcatcgcatt tccactcata acgacgatag ttaagctctt caaagacata
    28621 gcgagccagt agatactggg cttctgtccc tatccgtgtc cccctgagtt ttggagaaaa
    28681 agtgacagct cccacttcta ttactccgtt actggtcaat acgcatgaga gaaaaagttc
    28741 ccaaagcctt accagttgcc ttgtctatga ttgcatagta aaaacggtcc ttacgaccaa
    28801 catctgattt aaaaggctga ccagttcctc aatgtctgct actggctcct gaaagaggta
    28861 ggtccacatc tcctgaggag tatcaggacc ataaacagct agcaaatcct ccgcatgctt
    28921 ttccactgaa agagcctcta tcctagcata acgcccttct aagagatcaa taaaagtcag
    28981 ttcacctggt gtataacctt ccattgactc accaatcatc tgaccatatt cgtttactgg
    29041 tataactttc tccttgtttc gcttttcaaa ctttatagtt gcccatagta tagcgtattg
    29101 aaataagatg agaacaaatc gattgggaaa gtaaaattaa tttctataaa tgttttagca
    29161 attgtttcgt actattttag attcagtcta ctatatatca tactttcata agaaggttca
    29221 aaaaatcctc cagattctac tctgaaggat tcctatctta tttcacaaca atgttaacta
    29281 atttagttgg cttcaatagt ccagtggact attgaaggtg gcagatagag ctaataaact
    29341 cgttatttaa cgacgatatt aacgagttta ttcggtaccg caattacttt cacgatttcc
    29401 ttaccgtcaa tttctgcttt gactttttca tcagctaaag cgatttcttg taattcttca
    29461 cgtgatatat ctttagcaac catgagtttg gcacggactt ttcctttgat ttggacaaca
    29521 atttcaattt catcttcaac caatttgctt tcgtcccaag ttggccaagc tacataagag
    29581 attgactcac ctgtttctgc gactgtttgc cagagttctt ctgccaagtg aggtgcaaat
    29641 ggtgcaatca attgaataaa gcctttggca tagtcaacat aaagcttatc ttccttgtta
    29701 gcagcattga caaagaccat aagttgggca atagctgtgt tgaatttgag agactcaatt
    29761 tgctcagtaa cagctttgac tgtttcgttg taaaccttgt caagagcacc attgttttcc
    29821 gcaaggattt ctttacttgt aatcaaacgg taaactcggt caaggaactt acggcttcct
    29881 tccaaacctt cttctgacca agcaatcgaa gcatcgagtg gtcccataaa catttcataa
    29941 acacgaaggg tatcggcacc gtattgttcc accacatcgt ctgggttaac aacgttcttg
    30001 agcgatttag acatcttggc tggcgcttgc tccaactctt cccctgtttc tacatgaaag
    30061 aaggaaccat cacgtttttc aaccttgtcg gttgccacaa gagcaccacg gtggtcacgg
    30121 tagcttgttc ccaaaatcat cccttggtta aagagttttt ggaatggttc cttagtcgga
    30181 acaacaccga ggtcatagag gaatttatgc cagaaacgag cataaagcaa gtgaagtaca
    30241 gcatgttccg caccacccac gtagatatct actggcaacc attgtttgag gaggtcctca
    30301 tcagccaatt tctcagtatt gtgcgggtca atatagcgga ggtagtacca gcttgaacca
    30361 gcccattgtg gcatggtgtt agtttcacga cgacctttga caccatcttc acgagtcact
    30421 tcaagccaat ctgtcaagtt agctagtgga ctttcaccag tacctgaagg acggatatcc
    30481 ttggttacag gcaagacaag cggcaattca gtttcaggaa cagctgttga agttccatct
    30541 tcccaatgaa tgattggaat tggctcaccc cagtaacgtt gacggctaaa gagccagtcg
    30601 cggaggcggt aggtaacctt ctcctgacca cagccttttt cttccaagca agccacaatc
    30661 ttggcaatag cgtcttcttt attcaatcca tctaggaagt ctgaattgac atgcaggcca
    30721 tcctctgtgt aggcagcttc ttcgacattt ccaccttcaa gtacttcgac gattggaagg
    30781 tcaaattgtt tggcaaattc ccagtcacgt tggtcgtggg caggcacagc cataaccgca
    30841 cctgttccat aactagcaag aacatagtcc gcaatccaga ttggcatttc cttaccattg
    30901 acagggttga tggcataggc acctgtccaa acaccagttt tttccttagc aaggtctgta
    30961 cgaaccaagt cagacttaag gctggcttgg tgtttatagt ctgctacagc ttctgcttgc
    31021 tctgaacttg tgatagcgtc tactaattca tgttcaggag ccaagacagt gaaagtcgca
    31081 ccgaaaagtg tgtccggacg agtagtaaag actgtaaatt ccttgtctgt tccttttact
    31141 ttgaaagtta cattggcacc agttgattta ccaatccagt tgcgttgcat atccttgata
    31201 gactctgacc aatctagttc atctaagtca ttgagcaagc gctctgcgta agccgtgatt
    31261 ttgagcatcc attggcgcat tggtttgcgg acaactggat agcctccacg ctcagaagtt
    31321 ccgtcaggaa gcacttcttc attggcaatg gcagttccca attcctcaac ccagtttact
    31381 ggcacttcag cttcataggc caagcctttt tcgtaaagct tggtgaaaat ccattgagtc
    31441 cacttgtagt agtttggatc tgttgtgttg acttcacgat cccagtcata agaaaatcca
    31501 agcgcattga tttgacgttt gaagttggca atgttttccg ctgtaaattc tgctgggtca
    31561 ttaccagtat ccatagcgta ttgctctgca ggcaaaccaa aagcatccca acccattggg
    31621 tgaaggacat tgtagccttg cgcacgtttg taacgactga ggatatcggt tgcagtataa
    31681 ccttctgggt gtcctacgtg cagaccaact ccagacggat aagggaacat atcaagcgca
    31741 taaaacttag gttttgatgt atctgttcct gtcttaaatg tatgatgttc tgcccagtag
    31801 ccctgccact taggctcaat ttctttatga ttataaaaac tcatggtctc tctccaattt
    31861 tgtgatgtta ctattatacc atttttgagg gaatttgaaa tgtgtttaaa gaaaaaactg
    31921 tatactgtat ctcattaatt ttgatgacta tgaattgctc tatctcccac tttttatccc
    31981 attgttatgc agtaaatcaa ggagtaagtc aagacgctta tctcgtatag cacaaaatac
    32041 ttattttaga ccgaagataa aactggaatg ct
//
LOCUS       DAVHLA010000024        31442 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVHLA010000024 DAVHLA010000000
VERSION     DAVHLA010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31442)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31442)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31442
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.024"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            <1..155
                     /locus_tag="VVO77_001226"
     CDS             <1..155
                     /locus_tag="VVO77_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS1380 family transposase"
                     /protein_id="HEU5693240.1"
                     /translation="RTGRKQLLKLSSLYAYSELFSALYSRIRKVNLNLPVPYEPPRKK
                     ASLMMH"
     gene            complement(318..1487)
                     /locus_tag="VVO77_001227"
     CDS             complement(318..1487)
                     /locus_tag="VVO77_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000949617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU5693241.1"
                     /translation="MLSLDQIHLLLNTPEDEFHDFKQKWHHSKTELVRDILNFVNTSH
                     HEDCYIIFGIDNITLDIIGVNNDDNRRNEEDLTDLLHKLFISTNNQIKISIQTETIDN
                     KEIDILIIHDTDKVPVFLTKDYKPKKDTALPKGLIYAINGSINTPKDSSAPFELINEL
                     FQKFNHTDLNIKEQYFHVLKDYKNWFFIENEDGRFFIYNPNPDFYIKLNDDDANRFKT
                     MSYSLNQYQTNIDWQLVQLRYRHLTIDECMAMYLDQGNCLVPSPEVESFKIDYQETIY
                     YHCLYKNTLKYQLLKVFSSIPGLEKYPLTRFKNSIVIYDTKLELKKTHNLINSKFSSK
                     DIVNQLEVTEKDFDFYYKKARHKNPDYSIQENQVNLTELNLVRLLKTQIIHTSLN"
     gene            1849..2205
                     /locus_tag="VVO77_001228"
     CDS             1849..2205
                     /locus_tag="VVO77_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693242.1"
                     /translation="MKRDVRDIRKQFRLTEAEEKQILALMRERGETNFSDFLRKSLLS
                     SDLQKQMETWFALWQSQKLEQISRDVHEVLILAQSERQVTQEHVSILLTCVQELIQEV
                     ANTIPLSKEFREKYMR"
     gene            2210..2575
                     /locus_tag="VVO77_001229"
     CDS             2210..2575
                     /locus_tag="VVO77_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HEU5693243.1"
                     /translation="MEHRYRTNLKKVFLSDSELNQLNINIDQSGCKSFSEYARRTLLD
                     PGMNFITIDTNGYQDLVFELKRIGNNINQIARSVNQSQLIPGEELQELKKGIGELIKE
                     VDKEFNLQAQKLKEFHGHH"
     gene            2562..4385
                     /locus_tag="VVO77_001230"
     CDS             2562..4385
                     /locus_tag="VVO77_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002917262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEU5693244.1"
                     /translation="MVITKHFAIHGKSYRRKLIKYILNPEKTNNLALVSDYGMKNFLD
                     FPSYEEMVQMYHENFISNDTLYDFRHDRMEENQRKIHAHHIIQSFSPEDHLTPEQINR
                     IGYETVKELTGGKFRFIVATHVDKDHLHNHIIINSVDSNSDKKLKWDYKVERNLRMIS
                     DRFSKIAGAKIIENRYSHQRYEVYRKTNHKYELKQRLYFLMEHSRDFEDFKKNAPLLH
                     VEMDFRHKHATFFITDSTMKQVVRGKQLNRKQPYTEEFFKNYFAKREIESLMEFLLLK
                     VENMDDLLQKAKLFGLTINPKQKHVSFQFAGVEVKETELDQKNLYDVEFFQDYFKNRK
                     DWQAPETEDFVQLYQEEKLSKEKELPSDEKFWESYQEFKSNRDAVHEFEVELSLNQIE
                     KVVDDGIYVKVKFGIRQEGLIFVPNMQLDMEEDKVKVFIRETSSYYVYHKDAAEKNCY
                     MKGRTLIRQFSYENQTIPLRRKATVDMIKEKIAEVDALIELEVENQSYVTIKDELVHE
                     LAASELRINELQERMSTLNQVAEYLLASVESKQEMKLNLSKLNITENISANIVEKKLK
                     SLGNQLELERGRYEKMVVRLDKFINRLNTGLSKGDGIDFQK"
     gene            4499..5365
                     /locus_tag="VVO77_001231"
     CDS             4499..5365
                     /locus_tag="VVO77_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU5693245.1"
                     /translation="MGTLLATRLKNRRKELKMSQRELAEGICKQGQISRLESGEFTPG
                     ADFLHALAKKLKVSMDYFFDEQVVEEVNELSEFKKLAQTFITNRNYESLKYIYELENV
                     KAHRLSLADKFYMEWIKSLIDFYFYGQKEEAITRLENMLPQLNVSDLNYLQVSNTLFN
                     FYYDIEDLERFNEIRDKLEHQVNQLNLNTIEELELSIKFNYNVCRYLWLQKNIEEAIT
                     KITATIKQCKEYRTTYLLADLYLLMGSVSENFSSKSSVKEYFETAHFLYKLEENMSMA
                     LKVEHYFADITE"
     gene            5956..6207
                     /locus_tag="VVO77_001232"
     CDS             5956..6207
                     /locus_tag="VVO77_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000098314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693246.1"
                     /translation="MSSQMKAFLNELQGNMEVVGEFFDNPEKVIRKFGIVGREKEALL
                     IRDLNDMDDYALSIQNSVASPSGAHSSTCHFVRQDLQSA"
     gene            6436..6738
                     /locus_tag="VVO77_001233"
     CDS             6436..6738
                     /locus_tag="VVO77_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693247.1"
                     /translation="MKNKYDVKRIIPDELSESLDIFLKNYSETGLSDYNTYLFYGFIL
                     KSYKLPRENRYSIKLLVKELQNRGLKVTLIINIYYHALNCLALNDGLKIYEEDFLI"
     gene            6735..8081
                     /locus_tag="VVO77_001234"
     CDS             6735..8081
                     /locus_tag="VVO77_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase"
                     /protein_id="HEU5693248.1"
                     /translation="MNYEKYLNYLDYETEIEDAYHNLLLEYKISDNFSDEHWLYNLPS
                     NITQSKGFKIHLSASILNANLVAKKFFDFIFSREKKINFKILVSIKELSLQNTGLNGY
                     SQVGKFITIYPKDNKEFQRLLHKLEILYKGVKGVNIPSDFRFQLSEVVYYRYGEFVKD
                     STFKDKRDKKIPSNVNVPIRDYYIPRYNTIPDQYIILEVISKNAKGGVYKVFNTQKRV
                     YSLLKEASDLSLVDFTNRDSVNRLINEREILVELEKEEFTPKVFNDFYIKNSYFVEFE
                     FIIADKLSEYNMVSGSYDWFLTLIDYMEIINSKYNLSYRDLSFNNILIDNRNNIYIID
                     FEHALRKETQIEEKKLPLFGTPGFYETNLNLLNNQPEDIMGLVLLLYWSQNLDDFNVF
                     SKMSFLEAMEYAMNFNSRRLDTLDKSDWLYDIYKKAFNYKYDTFSELKKDFIEVLK"
     gene            8095..9012
                     /locus_tag="VVO77_001235"
     CDS             8095..9012
                     /locus_tag="VVO77_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000995574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5693249.1"
                     /translation="MNCFLKMNNVSVRYDDVIALKDITLQINKGDFIGLLGSNGAGKS
                     TLINSIVGFQEIYLGEIEYCDKDLIVSSQPFAHLGFTPQTTVIDFYTTVKDNVILGLN
                     LAGKFGKNAEKLCQIALEIVGLADKKNNLVETLSGGQLQRVQIARAIAHNPDFYILDE
                     PTVGLDTESAEKFLMYLKDKSLEGKTIIISSHDINLLEKFCKKILFLQNGSISFFGDM
                     RDFVDNSTIKLNFSMQNRISRYQIEFLENFRFKVHIEDNDSFTIEVPIEENILDVINE
                     VGKACEIKNFSTSKLTLQESYLQRIGGEK"
     gene            9009..9809
                     /locus_tag="VVO77_001236"
     CDS             9009..9809
                     /locus_tag="VVO77_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5693250.1"
                     /translation="MKADQLRHKSDLGLRGLAIIAKNEIIAFFRSKGLIISQFLQPIL
                     YVVFIIIGLNSSIKNIQFNDIKTSYAEYTIIGVIALLIIGQMTQVIYRVTIDKKYGLL
                     ALKLCSGVRPLYYILGMSIYSILGLIVQEIIIYIITLAFEINIAMDRFFYTVLLSIVV
                     LLFWDSLAILLTMFINDYRRRDIVIRFVLTPLGFTAPVFYLIDSAPSIVRWIGQLNPL
                     TYQLTILRNFYFKNSTTLELVFLLLTSLLVLISVSFIIPKIKLILIER"
     gene            9967..10440
                     /gene="tnpA"
                     /locus_tag="VVO77_001237"
     CDS             9967..10440
                     /gene="tnpA"
                     /locus_tag="VVO77_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISSpn6 family
                     transposase"
                     /protein_id="HEU5693251.1"
                     /translation="MREDNQSLSHTTWNCKYHIVFAPKYRRQIIYGRYKASIGRIIRD
                     LCERKGVIIHEANACSDHIHMLISIPPKLSVSSFMGYLKGKSSLMIFDKHANLKYKYG
                     NRKFWCRGYYVDTVGRNQKVIAEYIQNQLQEDRVADQLTLFESVDPFTGEINKRK"
     gene            10697..10918
                     /locus_tag="VVO77_001238"
     CDS             10697..10918
                     /locus_tag="VVO77_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU5693252.1"
                     /translation="MYRRLRDLREDHDLTQKQIATILSFTNSAYAKIERSEHALTADV
                     LVKLSDFYDVSTDYLLGLTDFPDKIRFRK"
     gene            11220..11453
                     /locus_tag="VVO77_001239"
     CDS             11220..11453
                     /locus_tag="VVO77_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000693750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU5693253.1"
                     /translation="MEIKYVSVENSVAEWADKKSILKRWEGLNLYTLNRWIKEMRENK
                     RFSLYVINPTHKLVFINLEGFECFLRWKQKRTK"
     gene            11529..13037
                     /locus_tag="VVO77_001240"
     CDS             11529..13037
                     /locus_tag="VVO77_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEU5693254.1"
                     /translation="MYYVTKTNSKGQPLYQVVEKYKDPLTDKWRTVTVSYTRNTSRAR
                     KQAEREVMDKIEKLTSSLESQYNPEMITTFGELKESWFQTWCVSVKPQTIKREELVIE
                     RLGKIIGDEFLLDRITPLLMKNCLNKYLDKYDASPSTMTHIKSTCNKIFNHGVLYNVI
                     KYSPMTAVKIDVPLEKKRESRKRLDAKFLAIHELQAFFDVLGQCRNASYYDLAIVLLL
                     TGIRIGEAAFLPSDVDFDKGILHIDKALQYHDLKVDEFYFDTTKTVNADREVALPIAA
                     SEAIQRTIKRNQEFEAYMEQNPSPAFKKCDSVFQTEYGSPITSHSFRQVLKRVEEKLL
                     KNCQKDYGFKWVKHVTPHSFKHMHISYLQSNEMHIAVKDIMTRVGHANFETTMGYTHN
                     ISRSQENTVTALNQFVEKHNFHFKELKSYTCKYSRMIEQFIETCDDNNKVELSVDEFK
                     DLLHLGSRYSPKHIVSNLLLKIKKDIVKYHPQFDIKIVKLSGNQIKGFSISW"
     gene            13118..13969
                     /gene="ylqF"
                     /locus_tag="VVO77_001241"
     CDS             13118..13969
                     /gene="ylqF"
                     /locus_tag="VVO77_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEU5693255.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEKAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            13956..14735
                     /locus_tag="VVO77_001242"
     CDS             13956..14735
                     /locus_tag="VVO77_001242"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEU5693256.1"
                     /translation="MATIKEIKEFLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQVVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            14751..16301
                     /locus_tag="VVO77_001243"
     CDS             14751..16301
                     /locus_tag="VVO77_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEU5693257.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            16887..17957
                     /gene="xerS"
                     /locus_tag="VVO77_001244"
     CDS             16887..17957
                     /gene="xerS"
                     /locus_tag="VVO77_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEU5693258.1"
                     /translation="MKREILLERINKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAINLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
     gene            complement(18030..19019)
                     /locus_tag="VVO77_001245"
     CDS             complement(18030..19019)
                     /locus_tag="VVO77_001245"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEU5693259.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(19083..20768)
                     /gene="lpdA"
                     /locus_tag="VVO77_001246"
     CDS             complement(19083..20768)
                     /gene="lpdA"
                     /locus_tag="VVO77_001246"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEU5693260.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELES
                     EEDGYLIAILKGEGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESSLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVITDKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            complement(20832..21875)
                     /locus_tag="VVO77_001247"
     CDS             complement(20832..21875)
                     /locus_tag="VVO77_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEU5693261.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     RVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            complement(22093..23085)
                     /locus_tag="VVO77_001248"
     CDS             complement(22093..23085)
                     /locus_tag="VVO77_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEU5693262.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDKNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            complement(23101..24069)
                     /locus_tag="VVO77_001249"
     CDS             complement(23101..24069)
                     /locus_tag="VVO77_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEU5693263.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            complement(24223..25584)
                     /gene="pdrM"
                     /locus_tag="VVO77_001250"
     CDS             complement(24223..25584)
                     /gene="pdrM"
                     /locus_tag="VVO77_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEU5693264.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTVRFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            complement(25595..25855)
                     /locus_tag="VVO77_001251"
     CDS             complement(25595..25855)
                     /locus_tag="VVO77_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693265.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            complement(25869..27137)
                     /locus_tag="VVO77_001252"
     CDS             complement(25869..27137)
                     /locus_tag="VVO77_001252"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEU5693266.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAAGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALFLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLS
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            complement(27150..27614)
                     /locus_tag="VVO77_001253"
     CDS             complement(27150..27614)
                     /locus_tag="VVO77_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU5693267.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            complement(27624..28277)
                     /locus_tag="VVO77_001254"
     CDS             complement(27624..28277)
                     /locus_tag="VVO77_001254"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEU5693268.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            complement(28415..29062)
                     /locus_tag="VVO77_001255"
     CDS             complement(28415..29062)
                     /locus_tag="VVO77_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693269.1"
                     /translation="MTTKKANITIEEYIEMSEVDFNEAVNYEFTSDTCQLANSIYQSL
                     FKFFDKKNFSDDLIFTWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLN
                     MNRNGCMGDFPHDFFDIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRFFSN
                     FDDFLEKNYLKTIWQVSKETPFSEMDFNMFKNISEKIIFERGSKMLNDLKSNYKK"
     gene            complement(29076..29789)
                     /locus_tag="VVO77_001256"
     CDS             complement(29076..29789)
                     /locus_tag="VVO77_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEU5693270.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLVPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            complement(30248..30628)
                     /locus_tag="VVO77_001257"
     CDS             complement(30248..30628)
                     /locus_tag="VVO77_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HEU5693271.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLAFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNA
                     AALLQAGAELSVIQTQLAELEINK"
     gene            complement(31050..>31442)
                     /locus_tag="VVO77_001258"
     CDS             complement(31050..>31442)
                     /locus_tag="VVO77_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEU5693272.1"
                     /translation="DHVQRNKNGQADTNQTEKPSEEKPQTEKPEEETPREEKPQSEKP
                     ESPKPTEEPEEESPEESEEPQVETEKVEEKLREAEDLLGKIQDPIIKSNAKETLTGLK
                     NNLLFGTQDNNTIMAEAEKLLALLKESK"
BASE COUNT        10064 a         5712 c         5863 g         9803 t
ORIGIN      
        1 ttcgaacagg acgcaagcag ctcctcaaat tgtctagtct ctatgcctat tccgaattgt
       61 tttcagcact ttattctagg attagaaaag tcaacctgaa tcttcctgtt ccttatgaac
      121 cacctagaaa aaaagcgtcg ttaatgatgc attaaagaac agtcgagatg aaaaaatcgt
      181 gtgacgcacc aagggaggag tctgcccttt tgaggaaatc tagcgaggaa aaacgatact
      241 ggaacagcag aaagtaaaac tgacctcatg aggaggaaga aagtggctca tgaggtcagg
      301 ggttttgtaa gttacatcta gttgagagag gtatgaatga tttgggtttt caataaccta
      361 actaagttta attcagttag atttacttga ttttcttgga tgctataatc aggattttta
      421 tgtctagctt ttttatagta aaaatcgaaa tctttttctg taacttcaag ttgattcact
      481 atgtcttttg atgagaattt actatttatc aagttgtgag tctttttcaa ttctaatttt
      541 gtgtcataaa ttactatact atttttaaat ctagttaaag gatatttttc gagaccaggt
      601 attgaagaaa atactttcag caattggtac tttaaagtat ttttgtataa gcagtgataa
      661 taaatagtct cctgataatc tattttaaaa ctttctactt caggggaagg gactagacaa
      721 ttaccttgat ctaaatacat agccatacac tcgtcaattg taagatgacg atatcgaagt
      781 tgtactaatt gccaatcaat attagtctgg tattgattta aactataaga catagttttg
      841 aaacgatttg catcatcgtc gttaagttta atataaaaat cgggattagg attataaata
      901 aaaaatcttc cgtcttcatt ttcaatgaag aaccaatttt tatagtcttt taaaacatga
      961 aaatactgct ctttgatatt taagtcggta tgattaaact tttgaaacaa ctcatttatt
     1021 aactcaaaag gagcagagga gtctttaggg gtatttatag agccatttat agcatatatt
     1081 aatccttttg gtaatgcagt atctttctta ggcttataat cttttgttaa aaatacagga
     1141 actttatctg tatcatgaat aattaagatg tcaatttctt tgttgtctat agtttcagtt
     1201 tgtatgctaa ttttaatttg attatttgtt gatataaaga gtttatgtag taaatctgtt
     1261 agatcttctt catttcttct attatcatca ttgtttacac cgattatatc taaagtgata
     1321 ttatcaattc caaagatgat ataacaatct tcgtgatgtg atgtattgac aaaatttaag
     1381 atatcacgca ccaattcagt ttttgaatga tgccattttt gtttaaaatc atgaaactca
     1441 tcttcgggtg tattcaatag taagtgtatt tgatctagac tcagcatttt tatttctcca
     1501 aatattagtt tacagaaatt ttatcataga atcagagaaa gtcaatcata actatattag
     1561 ctgtgatacc tttttcaaat cttccctgtt atcctaatat cattcataga aaatcaattt
     1621 ttgattttct atgggggttt gggggcgaag tcaccaagtt atcttatcgt tggctgtcaa
     1681 aactagaaag ttttgatagg ctggcgatat gatttttgag atattgtgga cacaatatct
     1741 gagctcgcaa agccttacaa gaatgaaaat cagttgttgg aaaagtgtac tgacattgta
     1801 tggtagctca cattgtcagt acaagtattt tggaaaggaa gtagcagtat gaaacgagat
     1861 gtgcgtgata ttcggaaaca atttcgttta acagaagcag aagaaaagca aattctagct
     1921 ttgatgagag agcggggaga gactaatttc tctgattttc ttcgtaaaag tttactttcc
     1981 tctgatttac aaaaacagat ggagacatgg tttgccctct ggcaatccca aaaactagaa
     2041 caaatcagtc gtgacgttca tgaagtttta atcttggcac agtcagaacg tcaagtcacc
     2101 caagagcatg tatctattct cttaacgtgc gtgcaggaat tgattcaaga ggttgcaaac
     2161 accatacccc tcagtaaaga atttcgtgag aagtacatga ggtaagcaca tggaacatcg
     2221 ttaccgaacc aatctcaaga aagtgttttt gtctgatagt gagttgaacc aactaaatat
     2281 aaatatcgat caaagtggtt gtaaatcctt ttctgaatat gcgagacgaa ctctactcga
     2341 tcctggtatg aattttatca cgattgacac aaacggttac caagatttag tgtttgagtt
     2401 aaagaggatt ggcaataata tcaaccagat tgctcgaagt gttaatcaat ctcagttaat
     2461 tcctggtgaa gaattgcagg agttgaaaaa aggaattggt gaattgataa aagaagttga
     2521 taaggaattt aatctgcaag cgcagaagct aaaggagttc catggtcatc actaaacact
     2581 ttgccattca cggaaagagt taccgcagaa agcttatcaa gtacattctc aatcctgaga
     2641 aaaccaataa tcttgccttg gtgtcggact atggcatgaa gaattttctg gactttccta
     2701 gctatgagga aatggtgcag atgtatcatg aaaatttcat cagcaacgat acgctttacg
     2761 attttcgcca cgacaggatg gaagaaaatc aacgaaaaat acacgctcac cacatcattc
     2821 agtctttctc gccagaggat catctcactc ctgaacaaat caatcggata ggttatgaga
     2881 ctgtgaagga attaactggt ggcaaatttc gttttatcgt tgcgacccat gttgataaag
     2941 accacctgca caatcacatc attatcaatt cagtagatag caattctgac aaaaagctca
     3001 agtgggacta caaggtggag cgaaatcttc gcatgatttc tgaccgtttt tctaaaatcg
     3061 caggtgctaa aatcattgag aaccgctatt ctcaccagcg gtatgaagtc tatcgtaaga
     3121 ctaatcacaa gtatgaactc aagcagcgac tctatttttt gatggaacat tctagggact
     3181 ttgaggattt caaaaagaat gctccgctac tacatgtgga gatggatttc cgtcacaagc
     3241 atgccacctt ttttattacg gactcaacta tgaaacaggt ggtgcgtggc aagcaactca
     3301 atcgcaagca gccttacaca gaagaatttt ttaagaacta ctttgccaaa agagaaatag
     3361 aaagtctcat ggaattttta ttgctgaaag ttgagaatat ggatgattta cttcagaaag
     3421 caaaactttt tggactaact atcaatccta aacaaaagca tgtttctttt caatttgcag
     3481 gagtggaggt aaaggagaca gagctagacc agaaaaatct ttatgatgta gagtttttcc
     3541 aagattattt taaaaataga aaagattggc aagctccaga aactgaggat ttcgttcaac
     3601 tttatcaaga agaaaagtta tccaaagaaa aagaacttcc aagcgatgag aagttctggg
     3661 agtcctatca agagttcaag agtaacagag atgccgttca tgaatttgag gtggagttgt
     3721 cactcaatca aattgaaaaa gtagtggatg atggaattta cgtcaaggtc aagtttggta
     3781 ttcgtcagga gggacttatc tttgtgccga acatgcagct tgatatggaa gaggataagg
     3841 tgaaggtttt catcagggaa accagctcct actatgtcta ccacaaagac gctgccgaga
     3901 aaaattgtta tatgaaaggt cgaaccttaa ttagacagtt cagctatgaa aatcaaacca
     3961 ttccattacg cagaaaagcg acagtcgata tgattaaaga gaagattgcg gaagtggatg
     4021 ctttgattga actggaagta gaaaatcaat cttatgtcac gattaaagat gagttagtgc
     4081 atgaactagc agcgtctgaa ttaagaatca atgagttgca agaacgaatg tcaaccttga
     4141 atcaagtagc agaatatcta ctggcttcag ttgaaagtaa gcaagaaatg aaattaaatc
     4201 tttcaaaact gaatataact gagaatatca gtgctaatat tgttgagaaa aaattgaaga
     4261 gcctggggaa tcaactggaa ttggaaaggg gcaggtatga aaagatggta gtcaggctag
     4321 ataaatttat aaatcgctta aatacaggac tttcaaaagg agatgggata gattttcaaa
     4381 aataggaatc tagccaataa ttatatacaa tgtgtatctt ttgtaaaata tatttgaaat
     4441 ttagatttaa tcatgttaca attaacattg aaatcaaata gaaaaggaag atgcaaacgt
     4501 gggtacacta ttagcaacaa gattaaaaaa tagacgaaaa gaattaaaaa tgtctcagcg
     4561 agaattagct gagggtatct gtaaacaggg gcaaattagt cgattagaga gtggagagtt
     4621 cacccctgga gcggattttt tacatgccct tgctaagaaa ttaaaagtta gtatggacta
     4681 cttttttgat gagcaggttg tagaggaagt caatgagtta tcagagttta agaagttagc
     4741 acagacattt atcacaaatc gtaattatga atctttaaaa tatatatatg aattggaaaa
     4801 tgtaaaagcc catcgcttat ctctagcaga taaattttac atggaatgga taaagtctct
     4861 tatagatttt tatttttatg gacagaaaga agaggcaatt acacgattag agaatatgct
     4921 acctcagtta aatgtatctg atttgaacta ccttcaagtt tcaaacactc tattcaattt
     4981 ttattatgat attgaagatt tagaacgttt taatgagatt agagacaagc tagagcatca
     5041 agtgaatcag cttaatttaa acacaattga agagttagaa ctatcaatta agttcaatta
     5101 taacgtttgt cgatacctat ggttacagaa aaatattgaa gaagctatta cgaaaatcac
     5161 agctacgata aagcaatgta aggagtacag gacaacttat ctattagctg atttgtattt
     5221 attgatggga agtgtaagtg aaaatttttc ttctaaaagt tcagtaaaag aatattttga
     5281 gactgctcat tttctctaca aacttgagga aaacatgtca atggctttga aagtcgaaca
     5341 ttattttgca gatataacag aataaggaat acggtgttct agtgagcatc gttttttaaa
     5401 tctaatttga atacaaaaaa gtattaaata aaaaaaaata aaaaaagatt ataaaaatac
     5461 ttgacaagct aattttgaag tgataaaata aatgcaagaa aacgaaagga gaggtatatg
     5521 agaagtttgt ttaggaaaat tgttgctttg ttagtcatag gattaatcct attagggact
     5581 gctggaggaa ctcaagttca taagatggct agagggattg atcaaggtcc tgcgaatggt
     5641 atttatagat aggagattat agtcacttaa aaatcaacaa attataaaat ttttgtttta
     5701 cttaaataga tattttatga tgggcgaagt ttttataact agttcctata agtacagaaa
     5761 cctattttaa tttactaatt tcaaaacaat tttttgagat atatgtaatt aaatctaaat
     5821 taagctttaa aaaattattt ttagcaattt gattttgaaa gtgtcatgca gcaatatgaa
     5881 agcgtagaat agaggtgttt ccaatgtaca agtaagtttt gattccaaat aaagtaatag
     5941 aaaaggagct atataatgag tagtcaaatg aaagctttct tgaatgaact tcaaggaaat
     6001 atggaagttg ttggagaatt ttttgataat cctgaaaagg taattagaaa atttggaatt
     6061 gtcggaagag agaaggaagc attgctaatc cgtgacttaa atgatatgga tgattatgct
     6121 ctttcaattc aaaatagcgt tgcatcgcct tctggggcac atagtagcac ttgccatttt
     6181 gttagacaag atttacaatc cgcataattg ttaatatata aaacataaaa tttcaatttt
     6241 caattaggga taatagaatt ccttactatg atatagaaag tgaattaatt aggaaatctt
     6301 agtcagaggt ttctgattaa ttcatttttt atatattaag agtgatgtga aatgttcaaa
     6361 ttgtgagact actctcggat tgttgtatag aaatttaaaa ttttattgtg agctttttaa
     6421 ggaagagtgg ccgatatgaa aaataaatac gatgttaaaa gaattattcc ggatgaatta
     6481 tcagaatcac tagatatttt tctaaaaaat tattctgaaa ctggattgtc agattataat
     6541 acttatctct tttatggttt tatcttgaag tcctataaat tgcctcgaga aaatagatat
     6601 agcataaaat tattggtgaa ggaattacaa aatagaggac tgaaagttac attgattatc
     6661 aacatttatt atcacgcttt aaattgtttg gctttaaatg atggtctaaa aatttatgaa
     6721 gaagatttct taatatgaat tacgaaaagt atttaaacta tttggactat gaaactgaaa
     6781 tagaagacgc ataccataat ttattattag aatataaaat tagtgataat tttagtgatg
     6841 aacattggtt atataatttg ccgtctaata tcacccaatc taagggattt aaaatacacc
     6901 tgagcgcttc aatattaaat gctaatttgg ttgctaaaaa attctttgat tttatatttt
     6961 ctagagagaa gaagataaat ttcaaaattt tggttagcat taaagaactt tctttgcaaa
     7021 atacagggct taatggttat tcacaagtcg ggaaattcat tacaatttat ccaaaagata
     7081 ataaagaatt tcaacgtttg ttacacaaat tagaaatatt gtataaaggt gtaaagggtg
     7141 taaacatacc atcagatttc agatttcaac ttagcgaggt tgtatattac agatatgggg
     7201 agttcgtaaa agatagcact ttcaaggata aaagagataa gaaaatccct tcaaatgtga
     7261 atgttccaat aagggattac tatattccaa gatataacac tattcctgat caatatatta
     7321 ttttggaagt gatttctaaa aatgccaaag gtggagttta taaagtattt aatactcaaa
     7381 agcgagttta ttctttatta aaagaagcta gtgatttatc gttggttgat tttacaaata
     7441 gagattctgt gaatcgttta ataaatgaaa gagaaatatt agtagaattg gaaaaggagg
     7501 aatttactcc aaaagttttt aacgattttt acataaagaa ttcgtatttt gtggaatttg
     7561 agtttattat tgcagataaa ttaagcgagt ataatatggt tagtggctcg tatgattggt
     7621 ttttaacatt aattgattat atggagataa taaactccaa atataatctt tcctatagag
     7681 atttatcatt taataatata cttattgata atagaaataa tatttatatt atagactttg
     7741 agcatgccct aaggaaagaa actcaaattg aagaaaaaaa gttgcctcta tttggaactc
     7801 cagggtttta tgaaaccaac ttaaatttat tgaataatca accagaggat attatgggat
     7861 tggttttgtt attatattgg agtcagaatt tagatgattt taacgtcttt tcaaaaatga
     7921 gttttttaga agcgatggag tatgcaatga attttaattc gcgtcgctta gacacacttg
     7981 ataaatcaga ttggctttat gatatttata aaaaagcgtt caattataaa tatgatactt
     8041 tttctgaatt aaaaaaagat tttatagagg tattaaaata aaggtagggg tgttatgaat
     8101 tgtttcttga aaatgaataa tgtaagtgtt cgttatgatg acgtaatagc tttaaaagat
     8161 ataactttac aaataaataa gggagatttc attggcttat taggttcaaa tggtgcaggt
     8221 aaatctacgt taattaattc tattgtaggt tttcaagaga tttatttagg agaaatagag
     8281 tattgtgata aagatttgat agttagttct caaccttttg ctcatttagg ctttactcct
     8341 caaaccacag taattgattt ttatactact gtgaaggaca atgtaatatt ggggctgaac
     8401 cttgctggaa agtttgggaa aaatgctgag aagttgtgtc aaatagcctt agaaattgtt
     8461 gggttagctg ataaaaaaaa taatttggta gaaacattgt caggtggaca actgcaacgc
     8521 gtccagattg ctagagcaat agctcataat ccagattttt atattttaga tgaacctacc
     8581 gttggtttag atactgaatc tgccgaaaaa tttttaatgt atttaaaaga taagagtttg
     8641 gaaggaaaaa ctattatcat atcttcacat gacataaatc tactcgaaaa gttttgtaaa
     8701 aaaatacttt ttttacaaaa tggctccata tcattttttg gtgatatgcg tgactttgta
     8761 gataattcaa ctatcaaatt aaatttttca atgcagaata gaatttctag atatcaaatt
     8821 gaatttttag aaaattttag atttaaagtt cacatcgaag ataatgatag ttttacaata
     8881 gaagtcccta tagaagaaaa tatcttagat gttatcaatg aggtaggaaa agcatgtgaa
     8941 attaaaaact tttcaacaag taaattaacc ttacaagaaa gttatttgca aagaatagga
     9001 ggagaaaaat gaaggctgat caattaaggc acaaatcgga cttaggttta agaggtctag
     9061 cgattattgc taaaaatgag attattgctt tttttagaag taaaggttta attatttctc
     9121 agtttctaca accaatctta tatgttgttt ttataataat aggattaaat tcttcgataa
     9181 agaacattca gtttaatgat ataaaaacct cttatgcaga atatacaatc attggtgtta
     9241 tagctttatt gataatcggg cagatgactc aagttattta tagggtgaca atagataaaa
     9301 aatatgggct acttgctctt aagttatgca gtggagttcg tcctttatat tatattttag
     9361 ggatgagtat ctattctata ttagggttga tagttcaaga aattattata tatataatta
     9421 cgttagcgtt tgagataaat atcgcaatgg atagattttt ttatacagtt ttgttatcta
     9481 ttgttgtttt attattttgg gactcccttg caattttact tacaatgttt atcaatgatt
     9541 acagaagacg tgatattgta atacgttttg tactaacacc gcttggtttt acagctcctg
     9601 ttttctactt aatagattct gctcctagta ttgtgagatg gattggtcag ttaaatccct
     9661 taacttatca attaactatt ttgagaaact tttattttaa aaattcaaca actttggaat
     9721 tagttttctt attgttaaca tcattacttg tccttatatc tgtatctttt attataccaa
     9781 agataaaatt gatactgata gaaagataaa agttgggtca tccaactttt ttgttgtctc
     9841 ccgaaaacca ctagctatgc tagtggttcc atagagcttt tagcgtggta acaaaaagaa
     9901 cctcctaaaa tgataagata gaagtggttt ctccgccact acaacatatc atacaggagg
     9961 tacctcatga gagaggataa tcaaagttta tcacatacca catggaattg taaatatcat
    10021 attgtttttg cacccaaata tcgtcgtcaa atcatttatg gcagatacaa agctagtatc
    10081 ggaagaatca tacgtgactt atgtgagcgt aagggtgtaa taatccatga agcgaatgct
    10141 tgttcagacc atattcacat gcttatcagt attcctccga aacttagtgt ttcgtccttt
    10201 atgggctatt taaagggcaa gagcagtttg atgatttttg ataagcatgc gaatttaaaa
    10261 tacaaatatg gcaatcgcaa gttttggtgt agaggctatt atgtagatac ggtaggccgt
    10321 aatcagaaag tgatagctga atatattcag aatcaattac aagaagacag agtagcagac
    10381 cagctcacgt tattcgagtc agtagatccg tttactggcg aaataaataa gaggaagtaa
    10441 ctaaggtgct ttagcacctg ctcgggaaag tggtgcgcga ggaagctatt tcggtgggcc
    10501 tttggccctg gccggtagaa gcggcttata gccgcagaac aaaccaccag ttcacactgg
    10561 tggttttgat ttaaaaaact tgatacataa aaataaaagt ctatataaag gatggtaaaa
    10621 ttcctgttgt ccgatttgga caatatccta aatagttaca atatatggtc tatacttttt
    10681 cttaggagaa agctagatgt acagacgttt gagagatttg agggaggatc atgatctgac
    10741 ccaaaagcaa atagctacaa tactttcgtt tacaaattca gcttatgcca aaattgaacg
    10801 gagtgagcat gcgttgacgg ctgatgtatt ggttaaactc tcagatttct atgacgtcag
    10861 tacagactat ttattgggat taactgattt tcctgataaa attcgcttta gaaaataatc
    10921 tcctcaattt catagagttt gaaaatgagt gagatttttt atttgccctt tgacaactga
    10981 atagcctaaa atggtacttt cctcatttgt ggagcagttt tgcttgattc gccaagatag
    11041 gagcggggac aatcaccaat aaaatagagc gatactctat ctgccatgat gcaaatgata
    11101 tacaatgata cttctgaacg ttcaggctgc cgtcgtaaaa gagcagtaag tgagattctt
    11161 atgatgaccc catcagtcat gccatggagg gagaagaaat tattcgaaag gatgataata
    11221 tggagataaa atacgtatct gttgaaaatt cggtagctga gtgggcggat aagaaaagca
    11281 tactgaaacg atgggaaggt ttgaatctct acactcttaa cagatggatc aaagaaatga
    11341 gagaaaataa gagattttct ttatacgtca tcaatcctac acataagctg gtgtttataa
    11401 atcttgaggg attcgaatgc tttttgagat ggaaacaaaa gcggacaaaa taaggaagtc
    11461 atggtataat atagagtagt tatttattct atacaacaat gatttatttc ttttcgagga
    11521 attaaattat gtattatgta actaaaacaa attcaaaagg acaacccttg tatcaagtgg
    11581 ttgaaaaata taaagatcca cttactgata agtggagaac agtaactgtc agctatacta
    11641 gaaatactag tagagcacga aagcaagctg aaagagaggt aatggataaa atagaaaaac
    11701 tgacctcttc ccttgaaagt cagtacaatc ctgaaatgat tacaactttt ggagagttaa
    11761 aagagagttg gtttcaaact tggtgcgtat ctgtcaagcc ccagacaata aaaagggaag
    11821 agttggtgat agaacggctt ggtaaaatta tcggtgatga atttttactc gatcgaatta
    11881 caccactact gatgaaaaat tgtcttaata aatatctgga taaatacgac gcttcacctt
    11941 caacaatgac acatataaaa agtacgtgta acaagatatt taatcacggt gtgctataca
    12001 atgtcattaa gtactctcca atgaccgctg ttaaaataga tgtgcctctg gagaaaaaga
    12061 gagaatcaag aaaaaggctt gatgctaaat ttcttgcaat tcatgaattg caagcctttt
    12121 ttgatgtttt agggcagtgt agaaatgcta gctattatga ccttgctatt gtattattac
    12181 tgacagggat tcggattgga gaggctgctt ttttaccatc agatgttgat tttgataagg
    12241 ggattttaca tattgataag gctctccaat atcatgattt aaaagttgat gaattttatt
    12301 ttgatacgac taagaccgtc aatgctgata gagaggtagc cctcccaata gcagcgagtg
    12361 aagcaatcca gagaactata aaaagaaatc aggaatttga agcctatatg gaacaaaatc
    12421 ctagtcctgc tttcaaaaag tgtgatagtg tatttcaaac tgagtatggt tctccgataa
    12481 cttctcactc atttcgtcaa gttttgaaga gggttgagga gaagttgtta aaaaattgtc
    12541 agaaggatta tggttttaaa tgggtcaagc atgtgacccc tcattctttc aaacatatgc
    12601 acattagtta tcttcaaagt aatgaaatgc acatagctgt aaaggatatt atgactagag
    12661 ttggtcatgc gaattttgaa accacgatgg gctacaccca taacatcagt cgttcacaag
    12721 aaaatactgt aactgcttta aatcaatttg tagaaaagca caattttcac tttaaagaat
    12781 tgaagagtta cacctgtaaa tattcgagaa tgattgaaca attcattgaa acttgtgatg
    12841 ataacaataa agtagagtta agtgttgatg aatttaaaga cttattacac cttggttcac
    12901 gttactcacc caaacatatt gtttcaaatt tactgttaaa aatcaaaaaa gatattgtca
    12961 aatatcaccc acagtttgat ataaagattg tgaaattaag cgggaatcaa atcaaaggtt
    13021 tttccatttc gtggtagttt tggtgttcgc ttggtgttta gacgatagta aaataaatga
    13081 ggggtgctaa acccttgcta cgaaaggaaa aaactcaatg gctactattc aatggtttcc
    13141 tggtcacatg tctaaagctc gtcgacaggt gcaggagaat ttaaaatttg ttgattttgt
    13201 gacgatttta gtagatgcac gcttgcctct atctagtcaa aatcctatgt tgaccaagat
    13261 tgttggtgat aaaccaaaac tcttgatttt aaacaaggcc gacttggctg atccagcaat
    13321 gaccaaggaa tggcgtcagt attttgaatc acaaggaatc cagacgctag ctatcaactc
    13381 caaagagcaa gtgactgtaa aagttgtaac agatgcggcc aagaagctca tggctgataa
    13441 gattgctcgc cagaaagaac gtgggattca gattgaaacc ttgcgtacta tgattatcgg
    13501 gattccaaac gctggtaaat caactctgat gaatcgtttg gctggtaaaa agattgctgt
    13561 tgttggaaac aagccagggg tcacaaaagg tcaacaatgg cttaaaacca ataaagacct
    13621 ggaaatcttg gatacaccgg ggattctctg gcctaagttt gaggatgaaa ctgttgcact
    13681 taagttggca ttgactggag ctatcaaaga ccagttgctt cctatggatg aggttaccat
    13741 ttttggtatc aattatttca aagaacatta tccagaaaag ctggctgaac gcttcaaaca
    13801 aatgaaaatt gaagaaaaag cgcctgtgat tattatggat atgacccgcg ccctcggttt
    13861 ccgtgatgac tatgaccgtt tttacagtct cttcgtgaag gaagtccgtg atggcaaact
    13921 cggtaactat accttagata cattggaaga cctcgatggc aacgattaaa gaaatcaaag
    13981 aattccttgt gacagtcaag gagttagaaa gccctatttt tttagagctt gaaaaggata
    14041 atcgctcagg agttcaaaag gaaatcagca agcgtaaaag agccatccaa gctgaattag
    14101 atgaaaattt gcgcttggaa tccatgcttt cttatgaaaa agaactttat aagcaaggat
    14161 tgaccttaat tgcaggtatt gatgaggttg gtcgtggtcc tcttgctggt cctgtagtcg
    14221 ctgcggccgt tattttacct aaaaattgta agattaaagg tctcaacgac agcaagaaaa
    14281 ttcctaaaaa gaaacatctg gagattttcc aagtcgttca agaccaagcc ttgtcgattg
    14341 gaattggtat catagataat caggtcatcg accaagtcaa tatctatgaa gcaaccaaac
    14401 tagccatgca agaagcaatc tcccagctca gccctcaacc agagcacctt ttgattgatg
    14461 ccatgaaact ggacttgccc atttcacaaa cctccattat caaaggagat gccaactccc
    14521 tctctatcgc agcagcatct atagtagcca aggtaacacg tgatgaattg atgaaggaat
    14581 acgatcagca gttccctggc tatgatttcg ctactaatgc aggatatggc acagctaaac
    14641 atctggaagg cctcacaaaa ctaggagtta ccccaattca ccgaaccagc tttgaacccg
    14701 ttaaatcact ggttttaggt aaaaaagaaa gttaattgaa aggaaatacc atggaggaac
    14761 aatcggaaat agtccgttct aagaaagaat tcgcctttgc atccagcact atactatccc
    14821 aagttggtcg aggaatcatt gtcggcctca tcgttggaat tatcgtcgga tcctttcgtt
    14881 tcttaattga aaagggcttc cacctgatac aaggagttta tcaagatcaa gggtacttag
    14941 tgcgcaatct ttttgtactg gttttgtttt atatactcat ctgttggctc agtgccaaac
    15001 taacacggtc agaaaaagat attaaaggct caggaattcc tcaagtcgaa gccgaactga
    15061 aaggcctcat gtccctcaac tggtggggca ttctttggaa aaaatatgtg ctaggtattc
    15121 ttgctattgc cagtggactc atgctgggtc gagagggacc cagcattcaa cttggagcag
    15181 ttggtggtaa aggaattgcc aagtggctca aatccagtcc agtagaggaa cgttccttga
    15241 ttgctagtgg agctgcagca ggtttagccg cagcctttaa tgctcctatt gcagcacttc
    15301 tctttgttgt agaagaagtc tatcaccatt tttcgcgctt tttctgggtc tcaactctag
    15361 cagccagcat cgtagcaaac tttgtgtctc tactcatgtt cggtttgaca ccagtattgg
    15421 atatgccaga taacattcct cccatgaccc tagaccagta ttggatatat ctcgtcatgg
    15481 gaattttcct tggattttca ggttttctct atgagaaagc tgtattaaac gttggaagag
    15541 tttatgactt gattggtcaa aaaatccatt tggatagggc ttattatccc atcttggctt
    15601 ttatccttat cataccagtc ggaatcttct tacctcaaat cattggtggc ggaaatcagc
    15661 ttgtcctttc tttaactgaa caaaatttta gtttccaagt tttattagct tactttttga
    15721 tccgctttat ttggagtatg attagctatg gaagtggact gccaggagga attttcctcc
    15781 ccattttagc tcttggttct ttgcttggtg ccttagttgg tgttatctgt gtcaatcttg
    15841 gacttgtcag tcaagagcaa ttccctatat ttgtcattct aggaatgagt ggctattttg
    15901 gagccatatc aaaagctccc ttaaccgcta tgatcctcgt aactgagatg gtaggagata
    15961 ttcgcaacct catgccactt ggtcttgtca ctcttgtttc ttatattatc atggatttgc
    16021 tcaaaggtac gccagtctat gaagccatgc tggaaaaaat gcttccagaa gaagtatcta
    16081 gcgaaggaga agttacactt atcgaaatac cagtttctga taaaattgct gggaaacaag
    16141 ttcatgaact caacttacca cacaacgtcc tcatcacaac tcaagtccat aatggcaaga
    16201 gccaaacagt taacggctca accagaatgt atctgggtga tatgattcac ctggttattc
    16261 caaaaagtga aattggaaaa gtcaaagatt tgttgttgta gtatgagcat ttacataatt
    16321 tatgttatgt aaatgctcag cttgatttat ttagaaaacc gattctcaga aatgagatcg
    16381 gttatttttt actgatgagg aattttacat ataaataatt gaactttatt aaaaataaga
    16441 ctataattaa ttaagttaga aatgataaag cataaagcta gaaaggagtt tactgtatca
    16501 aatctgtaca gtaagattaa aatcatgaaa aagaaaacaa tagtaattat agtgaaatga
    16561 aatagaaata ggataaaaca aacaggacaa tcaaatcaat ttctagcaat gttttagaag
    16621 tccagatgta ctattctagt ttcaatctat tatacaatgt gttttgtatc tcatagctcc
    16681 ttatatagct cttcagttat gtagtattaa cagaagttta gtgggtgaga ttttcattat
    16741 tttccttatt ctgttttgtt tgtaggtcta agtcttttta tcactttgaa aaactcctat
    16801 aacatctttc tgaaaaacta taattttctt gaaaaatata caagtctatg ctatactact
    16861 agtatactta cttatggaga aaatacatga aacgtgagat tttactggaa cgaatcaaca
    16921 aactaaaaca actcatgccc tggtatgttc tggaatacta ccaatctaaa ctggctgtgc
    16981 cctacagttt tacaaccctg tacgaatacc ttaaggaata tgaccgattt ttcagctggg
    17041 ttttggagtc tggtatttca aacgctgata aaatatccga tattccttta tcagttttgg
    17101 aaaatatgtc taagaaagac atggaatcct ttatccttta tctacgtgaa cgtcccttgc
    17161 tgaatgctaa tacaacaaaa caaggtgttt cacagacaac tatcaatcga accttatcag
    17221 cactttctag tctttacaag tatctaaccg aggaggttga aaacgatcag ggggaacctt
    17281 atttctatcg taatgtaatg aaaaaagttt caaccaagaa aaagaaagaa acccttgctg
    17341 ccagagctga aaatatcaag caaaaactct ttctaggtga tgaaacagaa ggttttctaa
    17401 cttatatcga tcaagagcac ccacaacagc tttcaaatcg agctctctca tcattcaaca
    17461 aaaataaaga acgagattta gccattattg cccttctctt ggcatctggt gttcgcttat
    17521 ctgaagctat taatctagat ctaagagatc tcaatctaaa aatgatggtt attgatgtta
    17581 ctcgaaaagg tggcaaacgt gactcagtca atgtcgctgc ttttgctaaa ccttatttag
    17641 agaattatct ggccattcgg aatcaacgct ataaaacgga aaaaacagat acagcccttt
    17701 ttttaactct ctacagaggt gttcctaatc gtatcgatgc ttctagcgtt gagaaaatgg
    17761 ttgctaaata ctcagaggat tttaaagtac gtgtaacacc ccataaactg cgccatacac
    17821 tagcaactag gctctatgat gctactaaat cacaagtttt agtcagtcac caactaggac
    17881 atgccagcac acaagtcact gacctctata cccatattgt taatgatgaa caaaagaatg
    17941 ctctggatag tttatgattt tacgtatttt aaattatgta aataaatatc aaaaaaagaa
    18001 gttggttagt tggccaactt ctttttgatt tatccaacta ccgcttcagc gatttcttca
    18061 cggctaatac cagcgaagta gcgtgtgata tcaatggttt ttagcgcctt aagaacatct
    18121 tcgcgttcgt atttcacccc acgaaggaca tcttctactg cagcaacgtc ttcaatacca
    18181 aagaagtcac cataaatctt gatgtcttgg atttttgatt cagtaacgtt agcaaagact
    18241 tcaaccttac cactagtgaa tttggttcca cgacggacgt taaattcagg tgatttacca
    18301 tagttccagt cccaagttcc aaacttagta tccttgatgc gattgatttc ggccaattct
    18361 tcttctgaaa agacgtattc agtcatctct gggtactctt ttttcatgta ttccaagagt
    18421 aaatcacgga atttttcgac tgtgattttt tttggtaatt cattgataat attggttaca
    18481 cgggcacgga cggatttcac accttttgat tcaaatttat cttttgaaac cttaagggca
    18541 tttgcgagga ctgacaaatc aacgtcaaag agcaagcaac cgtggtgcat gatacggccg
    18601 ttgatatagg cttgggcatt gccacagaac ttcttaccat caatctcaag gtcattacga
    18661 cctgtgaact cagctttaac cccaagttga gccagggtat tgataaccgg agttgagaag
    18721 ctcttgaagt caaatgcctt attttcatct tctttggaga tgatcgtgta gttgaggtta
    18781 tttaaatcgt ggtaaacagc tccaccacca ctaatacggc gaactacctc aataccattt
    18841 tcgcgaacat aatcacggtt gatttcttcg atagtgttct ggtgacgacc aacaatgata
    18901 gatggcttgt taatccaaag taggaagatt tgatcctcat ccaaaaggtg tttaaaggcg
    18961 tattcttcca aggcaatatt aaaagcagtg tcatttgaat gattgataat gtatttcatg
    19021 atatcccttt actttatatg atagaaactg gaaataacct tccagtctaa tctatctttg
    19081 ttttattttt tcttaggtga atggatggcc attcctagaa catctgcaaa cgcttcgtac
    19141 atcacttcag agtaagttgg gtgcccgtgg atggtcttca gcatttcctc aacagtgatt
    19201 tccatttcga tgatgcttga tgcttcgttt attaattctg cggctgcagg accaataatg
    19261 tgtacaccaa ggatttctcc gtatttctta tcagtgataa cttttacgaa accttgagca
    19321 gcgtcagatg caatagcacg accgttagca gcaaagttaa acttaccgat ggcaacatcg
    19381 tatttctcac gggcttgttc ttctgtcaaa cctactgctg ctacttcagg gagagtgtag
    19441 atggctgcag gagtcaaatt caatttggca actgcatgat ttcctttaag ggcattttca
    19501 gcggaaactt cacccatgcg gaaagctgcg tgagccaaca tcttagtacc gttgatgtca
    19561 cctggtgcat aaatgcctgg aactgaagtt tccatgtatt cgttgacctt gatacaacca
    19621 cgatccaatt caaactcaac ctctccaata ccttcaaggt ctggcatacg accaattgaa
    19681 agaagagctt tgcttgcgat gatatcgtct tttccttcaa ccttgatacg aagttgacca
    19741 ttttcctcaa tgatttcttg cagtttagta ccagtcaaga tggtcattcc tttacgctca
    19801 aggatcaagc gaaggttctt agaaacttcc gcatccatag ctggaactat acggtccatc
    19861 atttcgataa cagtcacttt tgaaccaaat gtcatgaagg cctgaccgag ttcgataccg
    19921 acaactccac caccgatgat aacaaggctt tctggcactt cgttcatttc aagaatgtca
    19981 tcactagtca tgacaagtga agattccata ccagggacgt tgatcttgct gacttttgaa
    20041 ccaccagcaa gaatgatttt cttggtttca agcaattcag aaccatttac caagacgttc
    20101 ttgtctttag tgattgtacc aattccttta tgaacagtaa ctccgtagct acgaagaagt
    20161 cctgcaacac caccaacaag agtattaaca actttagatt tagtttctaa aagtttttcc
    20221 atatcaacag tgaagttagg attttcaatc acgataccac gatttgcagc atgaccgata
    20281 ttttcaataa tttcagcgtt atgaaggtag gtcttggttg gaatacatcc acggtttaag
    20341 caggttccac caagttcaga tttctcaaca agggcaacct taccgccgag ttgggcagct
    20401 ttaatggctg caacataacc agcaggacct ccaccaatca caacgatatc aaaagcatca
    20461 tcgctcttac catcatcgtt tgaggtactt gctacaggta cagggctagc ttctggcgat
    20521 gctgctccag ctgttgggat gttttccctt tcttcaccaa ggtaaccgat aacttccgtt
    20581 acagggacag tttcaccctc tcctttgaga atggcaatca agtacccatc ttcttcggat
    20641 tccaattcca tgctgacttt atcagtcatg atttccaaaa ggatttctcc ttcttttaca
    20701 aattctccga cttttttatt ccattggacg atttgtcctt ctgtcatatc cacgccggct
    20761 tttggcataa ttacttctaa ggccatgtct tccttccttt atctatatct taaaaatgaa
    20821 tactcttgct cttaaatcaa cattgagatt ggggtttcaa tcaactcttt caagtccttc
    20881 ataaacttag caccagccat accatctacg acacggtggt caatagttaa tcctaaactc
    20941 atgattgggc gaatcacaat ttcaccattg acgacaactg gcttctcgat tgtcgaactg
    21001 acaccaagga tagctgagtt gggttggtta ataatcggac caaaggactg aacaccaaac
    21061 attcccaaat tactgattgt gaatgttgaa ttttgtaact cacttggagc caatttacca
    21121 tccaaggtac ggccaataac atccttaaag gctacaacca gttctgaaag actcatcttc
    21181 tcagcattgt aaacaacagg tgtcatcaat ccattatcca tcccaactgc catggcaaga
    21241 ttgacatagt tgtgagtgat aatagtcttg ccatcttctg tcaatgaagc gttgatgtat
    21301 ggatgtttca taagagtctt aacaactgca agtgaaagaa ggtctgttac agtagtcttc
    21361 ttcccagttg cttccatgat tggctcaaga accctcttac gaagagccaa catttcagtc
    21421 atatcaactt catagttgag ggtgaaggtt ggcgcagtca agtaagattc aaccatgcgt
    21481 tgggcaataa ccttacgcat tggtgtcatt ggaatacgct cgatttcacc atatggtgtt
    21541 acgttatcag ggacttcttc cactttttca atctgagcag gagatttgat gctatcgttt
    21601 tcgatatttt caggaagcag ggccaaaaca tccttcttca tgattttacc acgatgaccg
    21661 gttccttgga tttcctgcca agcaatgtta tgttcgaggg caattcgttt tgcaagtggc
    21721 gaaatgcgaa ccacgtttgt gtctttataa gtttccacgt cttctttgtg gacacgaccg
    21781 tttgcacctg agccagaaac gtcgtagagg tttatcccta aatcatccgc taactttcta
    21841 gctgcaggag tcgctcttag cttgtcatca gccatgacct ctccaattct atttatgata
    21901 caaagggcgt caaaagcgac tgaaaaatag gaaatcgacg atggcttcga tgaagccaag
    21961 gagatttatc ttttttccga gcttttagcc cgtgctctaa tctaagatat taatgacgaa
    22021 gagctctgca cctaaaagat acaaagtttc tcgtcagctt tattttattt acataactta
    22081 tcttatgtaa ctctattctt tgttataagt ttttcggatt gcatctttga tactttcaac
    22141 tgttggaatc attgcatttt ctaggttttg tgcataaggc atcggcacat cttctcctgc
    22201 acaacggcga attggtgcat ctagatagtc aaatgcttct gattctgaaa taatagctga
    22261 aatttcaccg atatagccac ttgttttgtg ggcatcgttg accagaacaa ccttaccagt
    22321 cttcttcact gagtttatga tgatatcctt atcaagcgga acaagggtac gtgggtcaac
    22381 aatttcaact gaaattcctt cttctgctaa ttcttcagca gcttgaacca cacggcgaag
    22441 catttttcca taagtaacaa ctgttacatc cgttccttgg cgtttgattt caccaacccc
    22501 aagtggaatt gtgtagtctg gatcaactgg cacttcccct ttttggttaa attctgactt
    22561 gtactcaagt ataataactg ggtttttatc acggatagaa gacttaagca ggcctttcat
    22621 gtccgcaggt gttccaggtg ccacaacctt aagtcctgga atgtgagtaa accaagactc
    22681 tagagattgt gagtgctggg cggcagagcc aactccgtta ccagctgcac aacgaacagt
    22741 cattggaacc tgacctttac caccaaacat gtaacgtgtt ttagcagctt ggttgacgat
    22801 attgtccatg gcaataacag agaagtccat gaaggtcata tcgacgattg gacgaagtcc
    22861 tgtcatggca gctcctgctg ctgctccaga gatggcagct tcagaaatcg gacagtcacg
    22921 gacgcgttct ggaccaaatt cttcaagcat tccaacagaa gtaccgaagt ctcctccgaa
    22981 gacaccgacg tcttctccca tcaagaacac attttcatcg cgacgcattt cctcagacat
    23041 agcaaggata atggtgtcac ggaaggacat tgtttttgtt tccattttat ctctttctcc
    23101 ttagtctgcg taaatatctt caaaggctga ttcaagcggt gggaatgggc tttcctctgc
    23161 aaatttaaca gaagcttcta ctgcttcctt tacttgcgct tggatttctt ccaattcttc
    23221 ggcacttgca atgttatttt caataaggta attgcggagg ttttcgattg gatctttttg
    23281 tttccacaat tccacttctt cacgcgtacg atatttacca gggtcagatg atgagtgacc
    23341 gagccagcga taagttacac tttcaatcaa gactggacca ttgccactgc gaacatggtc
    23401 cacagctttc tgaaatcctt catagacatc gatgacattg ttaccatctt cgatgaacat
    23461 tccaggaatt ccataagcgg cgctacgttg atggatatgt tctatattgg tcattttctt
    23521 gatatccgca gagataccgt aaccgttgtt aatgcaatag aaaatgactg gcaggttcca
    23581 gatagaagcc atgttcactg cttcgtggaa aacaccttca ttggtcgcac catctccaaa
    23641 gaagcagaca acgattttac cggtattttg catttgctga ctgagggctg caccgacagc
    23701 gatccccata ccaccaccta caataccatt ggcaccaagg ttcccagcat caaggtcagc
    23761 gatatgcata gatccacctt tccctttaca ggttccagtg tatttaccaa ggatttcagc
    23821 catcattccg ttgaggtcaa tccctttagc aatagcttgc ccgtgtccac ggtggtttga
    23881 ggtaatcaga tcatctggat tgagagctaa catagccccc acgttagctg cctcttcacc
    23941 aacagaaaag tgcgtcattc ctggcacttt ccctttcttt actaattgtg caatttttaa
    24001 gtccatgcga cggatttctt ccatcttacg gaacatttct agcaaaagat ttttatctaa
    24061 agttgacatc ttcttgcctt tctaactttc ttcttacctt actattttac cgtttttggc
    24121 aaatactgtc aaagtttttc taaaagaaat ttcacaaaat aaaaaagaaa accccgtgaa
    24181 aacaagggat tttcttatca agaatatttt ttcacaaact ttttagcgtt tggattttgc
    24241 taaagattca aatctcttca taatcacagt taaacgccaa cggtagagcg ccccactcac
    24301 aatcaaacta ataatcaagc cgatccagta agaataagct ccaaaatctg ttagagaatc
    24361 aaatagcgta gccacaggga ttgctacgcc ccaataacca agcaaaccaa ggtaaaaagg
    24421 aataactgta tccttatacc cccgcaaaat tccctgaagc ggcgccgcaa aggtatctgc
    24481 taactggaag aaaagactat aagttaaaaa acgcactgtc aaatcgataa attttgggtc
    24541 gttaccataa agactggcca catttcccct aaaaatgtaa aggaaggtta aggtgaaggc
    24601 cgcaaaaatg agggcagtcc atcttcctag accaatatag gttttcgcat catcaaatcg
    24661 cttggctccc acttcatagg aaacgacaat agccatagcc gatgagatac tcataggaaa
    24721 ggcgtacata agacttgaaa agttcatagc tgactggtga ctagctataa tcaaggacga
    24781 aaacttagcc ataatcaagc caaccactga aaagatagcc acttccgcga agacagttcc
    24841 cccaataggc agacctaaac gaactccttc cttaatttta tccatattaa gtggaattcg
    24901 tttctcaagg tgtaaggctt tgagcttctc ctgtttaaat aaaaccagaa cagaaatccc
    24961 aagcaagacc cagtaggcca aggatgttcc taaaccagca ccagcccctc ccagttctgg
    25021 aacaccaaag gcaccgtaaa tcaagagata gttaaatccg ctattgagag ggagtaacaa
    25081 aagcatgagg tacatggaca gtttggtcaa gcccagcgaa tccagcaagg aacgaatgac
    25141 gctaaagagc aacaagggga taatcccgat agataaaaac caaagatagc gaaccgctac
    25201 tgccgctact gctgcttcta acccaatatg attcaagatt gttggtgcca agaaaagtac
    25261 catccccagc aataccacag ataggcccaa ggccaaataa ataaattggt aaaaatcaga
    25321 cgcaacttct tccttttttc ctcgaccaag atggtgacca atgataggca ccaaggctga
    25381 cacaatccct gttagaaatg taaagaaagg attccagata ctggttgcca tagatacacc
    25441 agccaagtcc atagtgttgt attgacctgt cattgcagta tcaacaaaag aggcagaata
    25501 attggcaaat tggtaaatca ggattgggaa gaaaattttt aaaaataata ctaacttctc
    25561 tcgtaaacac tttgtcttat acatacttct ctttctattc tgatttatct aaaccaaaga
    25621 gtttcagacc atagtttttc aaacttagcg gaggtttatt agattttgaa gtagtatgcc
    25681 aacacgcaca tgtacgacaa taatagcttc taactaaacc tccgttatca tattgaaccg
    25741 catggtcagc tttttcttta gtttcatatt gaattttgga acgattagct gcgggacagt
    25801 aaattccact attagatttc gcttgtctct ccctacgttt tcgaaaataa ttcatattct
    25861 aactcctatc aagcttgata gacgatttgt cccttacaga tggtatattt aacctgccct
    25921 tttaaggttt caccgatgaa tggtgaatta gctgctttgg aagcaaaatg ggagtccaca
    25981 aggcggtcag ccttggcatc aaaaatagtg atatctgctg gaccattctc agccaagtaa
    26041 cctgcttcaa agttgtaaag cttggctggg ttgtatgtca ttttttcaag taattccatc
    26101 aagctcaact caccagcttc tactaaatag gtcaagctga gagacaggga tgtttctaag
    26161 ccagtcatac cagatggcgc tttggtaata tcctcaacat ttttttcatc tacatgatga
    26221 ggcgcgtggt cagtcgcaat aactgtgatg acacctgatt tgagaccttc gataacggca
    26281 cgacggtctg attccaaacg aagcggtgga ttcatcttag cattgctacc ttgtgttaaa
    26341 aaaagtgctt ctgtcttaga gaaatgctgt ggcgctactt ctgctgtgac ttctgcacct
    26401 aacccctgag caaactccac tactttaaca ctttcttcct tagacaaatg ctggatgtga
    26461 acatgggctt tagttgcata ggcaatcatg acatcacgcg ccatcatagc gtactcagcc
    26521 accccagtag caccgcagat atggaaatgt tctctagcaa tattttcatt aaagccaaga
    26581 acaccgttca aacctggatc ttcctcatga aggctgataa aggtattgag ttttttggct
    26641 tcctccatgg cttccttgac aatcttactg ctctcaagcg gaataccgtc atcagagaaa
    26701 ccagccgcac cagcttctaa gagcgcctta aagtcagtca agtttttacc attaaagttt
    26761 ttagtaatgg tcgcaactgt cttgacatta atcttctctt tggcagctga ctggagaact
    26821 gcttgcaaag tctccacgtc tgaaatggtt ggactggtat tagccatcat gacgacagta
    26881 gtaaaaccac ctgcagcggc tgccagggca ccagtatgaa tgtcttcttt atgtgtttga
    26941 ccaggttcac ggaaatgcac atgaatatcg accaaaccag gagcaaccac aagaccagta
    27001 gcatcaatcg tttctgctcc ttcttccgtg atctcaggcg caattttgat aattttccca
    27061 tcttgaacta agacatcaca aacttgatcc aaaccagact tgggatccat tacacgacca
    27121 tttttgatta gtagcatctg ctttctcctt tattcataga aatcaacttg ggtatccaac
    27181 aatttatccc catcataaac aaacttggct gaaaagaagg gtttatcctc taaaagccac
    27241 tcaacaaagg tgtggtcacc ttcccaagtc ggcttgctca aaacctcatc atagggaacc
    27301 cattctagcg tcccctcatt gcagtcaatc aagtcgccct caaactccgt caccttaaaa
    27361 acataggtgt accagtctaa atctggtgta aattcaggaa aagtgatgac accttttaga
    27421 actggcttgg ctttgagccc tgtttcttca aggatttcac gcgccgcgca ttcctggggc
    27481 gtctctcctc tctctagctt accacccaca ccaatccatt tcccttcatg gacatcattg
    27541 ggtttcttat tacgatggag catgagcagt tctttcccat tatcaatgta gcaaatcgtc
    27601 gctaactgag gcatattttc tccttatcta agccaatcga ttggctcttg tcctgtctct
    27661 tttaagaatg cattggcctt ggaaaagggc ttggaacccc aaaatcctct ataaaccgac
    27721 aaaggacttg gatgggctga ttcgataatc aagtgatgag gattggtaac taatgccttc
    27781 ttcttacgtg cataagctcc ccagagtaca aaaacgactg gtctatctag atgattgacc
    27841 acctgaatca cagcatcagt aaaaggctcc cagatttgac cagcatgacc attggcctgt
    27901 ccagcaggaa cagtcaaaca agcattaaga agcaagactc cttgctcagc ccaagctgtc
    27961 aaatcatgag atttcttaac tccgatatca tctgacaatt ctttcaagat attttgcaag
    28021 gatggtggag ctgggataga gtcaggtaca gaaaaactca agccctgcgc ttgacctggt
    28081 ccgtgatagg ggtcttgccc tagaattacc accttaactt cttcaagcag tgttgtcaag
    28141 agagcctgaa aaaccttttc cttgggtgga taaataatcc cctgagaata gacctgctcc
    28201 ataaactgat tgattttccc gaaataaccc tcaggtaatt gcgccttaat caaagcatgc
    28261 caagacgagt gttccatagc cgactccttc atttttactg cctctattat agcaaaaagt
    28321 ggctatggaa accacttttt acagtttatc taaagattta ataaatcgac tatatatacg
    28381 atttgaatac gtgaatacag tttataaaga ctggctattt tttataatta ctttttaaat
    28441 cattaagcat tttactacct ctttcgaaga ttatcttttc tgaaatattt ttaaacatat
    28501 taaaatccat ttcagaaaaa ggagtttctt tagaaacttg ccatatagtc tttaaataat
    28561 ttttttctaa aaagtcgtca aaattagaaa aaaatcgaaa atacaatgca ttctcttggt
    28621 gtaaaatcgc tctttttaaa ggataatact ctttaatatt attaactttt tgttcgtagg
    28681 catattttgc tacatgatct aggtatatat caaaaaagtc atgaggaaaa tctcccatac
    28741 agccattacg attcatattg aggctatatt ttcgattagt aagataattc ggaaatatat
    28801 ttcctattac tctaagatta tctacttgtg aatcccttct cccaatataa tccccttctt
    28861 tgactaatga tggagatttc caagtaaaaa ttaaatcgtc agagaaattt ttcttatcaa
    28921 aaaacttaaa aagagattga taaatactat ttgctaattg acaagtgtca gatgtaaatt
    28981 cataattaac agcttcatta aaatcaactt cagacatttc aatgtactct tcaatagtaa
    29041 tattagcttt ttttgtagtc attagctaat ctcctttaaa atgtgatctt ttcaagaata
    29101 tttttatcta aacaatccag caagtcttgg taagaataga cttcgtaagt cggctgggct
    29161 tgtgtgtgat tttcgaggtg atgaggatta taccagatag tgtcaatccc cgcattattg
    29221 ccaccttgaa tgtcggcggt tagagaatct ccaatcatca gcgtcttttc tttactaaat
    29281 ccagcaattt gctggccaat cttttcataa aagagagcat ccggcttttg agtttgcaac
    29341 tgttctgaga taaagacttg attgaaataa ggtactagac cagattgagc caaacgtcct
    29401 gtctgaatgg cagtaatgcc atttgtcgca gcatacaagt tataatcacg ctcaatgagg
    29461 ctgtccaaga gatcatgagc gcccgatagt gtttgtccct gctgagcgag ataaaattgg
    29521 taacgctggg caagaaaact accgtctttt tcctgtccaa aatgagaaaa taaacgagaa
    29581 aagcgcgtgt taaccagctc ttgtttactg attttcttca gctccaagtc tttccagaga
    29641 gccttgttca taggaacgta ataatcttta taagcctgaa tatccgcaac tccttcttct
    29701 tttagaagtt gggtcaaagc cacatcctca gcagcatcaa aatcaagaag agtgtggtcg
    29761 aggtcgaaga gtagaaattt gtagaacaat ttgaggtttt cctttctgaa aattcattaa
    29821 gaacattata tcataaagca cctcatacaa ttaactaatt taatcactta aaaaaaattc
    29881 gaacactttc tatacaactg acagctcaaa tctttcagaa tagaacaata ctaactatcg
    29941 agcaccctgt cttcataaat atatgtgtaa ttctagacct agaattccta taaactaaat
    30001 gctttcatac tcttccaagt aattgattgc cttaaatttt aatttttgaa ggattctaaa
    30061 gctagaatag tcccatcaca atcagttttg attgattcac aatttagaaa cactatagtt
    30121 tcactcctgt taaaataaaa aggaactgca taaagcaatc cctttctgat tttgaaatca
    30181 tttacttaac attttatagt tgagataatc aatagcttac ctataaaaag agttatagta
    30241 aaattcctta tttattgatt tcaagctccg ctaactgtgt ttgaataact gacagttctg
    30301 caccagcctg aagaagagca gctgcattat aggcaccttc tacaattgga accctgttga
    30361 tgatgatact tttatcactg aaatcagtca ccatttttaa gttcatttta gcagaaccta
    30421 ggtcaaaaaa ggcaagtaaa gtatctgctg gattttcgga aacaacccta tctacttgat
    30481 caaaactcgt tccaattcct ccgccctcgg ttcctcctac ataagtaatc ggaacatctt
    30541 tagctacttt actaatcagt tcaacaacac cttctgcaat gtgtttggaa tgtgaaacga
    30601 taacaagacc aataccaata ctttccatca aaccacccca gtttctaaaa tagcagtaaa
    30661 gagtaatcct gatgagaatg atccaggatc aatatgtcca agaaaccaca tgctcctaag
    30721 acaagagcta acagactggc catcaataat agtattgttc tttttttcat cattactcct
    30781 taactagtgt ttaactgatc aattagccag taaatagttt atctttattt acactatctg
    30841 ttaagatata gtaaaatgaa ataagaacag gacagtcaaa tcgatttcta acaatgtttt
    30901 agaagtagag gtatactatt ctagtttcaa tctactatat tttgcacatt ttcatgaaaa
    30961 aaatgagaac tagaactcac attctgctct catttttcgt tttcccgttc tcctatcctg
    31021 tttttaggag ttagaaaatg ctgctacctt tacttactct cctttaataa agccaatagt
    31081 ttttcagctt ctgccataat agtattgttg tcctgggtgc caaatagtaa attatttttt
    31141 aatcctgtga gagtctcttt ggcattggac ttgataattg gatcctggat ttttccaagt
    31201 aaatcttcag cctctctcag tttttcttca accttttcag tctcgacctg aggttcttct
    31261 gattcctctg gtgattcttc ttctggttcc tctgttggtt ttggagactc tggtttctcg
    31321 ctttgcggtt tctcttctcg aggggtttct tcctcaggtt tttctgtctg aggtttctcc
    31381 tcgcttggtt tttccgtttg attggtatca gcttgaccat ttttgtttct ttgaacatgg
    31441 tc
//
LOCUS       DAVHLA010000025        31003 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVHLA010000025 DAVHLA010000000
VERSION     DAVHLA010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31003
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.025"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(43..237)
                     /locus_tag="VVO77_001259"
     CDS             complement(43..237)
                     /locus_tag="VVO77_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEU5693273.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(302..1438)
                     /gene="dnaN"
                     /locus_tag="VVO77_001260"
     CDS             complement(302..1438)
                     /gene="dnaN"
                     /locus_tag="VVO77_001260"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEU5693274.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(1597..2958)
                     /gene="dnaA"
                     /locus_tag="VVO77_001261"
     CDS             complement(1597..2958)
                     /gene="dnaA"
                     /locus_tag="VVO77_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEU5693275.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(3171..3929)
                     /locus_tag="VVO77_001262"
     CDS             complement(3171..3929)
                     /locus_tag="VVO77_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEU5693276.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNYFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(3987..5168)
                     /locus_tag="VVO77_001263"
     CDS             complement(3987..5168)
                     /locus_tag="VVO77_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEU5693277.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVIVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            5351..5830
                     /gene="rlmH"
                     /locus_tag="VVO77_001264"
     CDS             5351..5830
                     /gene="rlmH"
                     /locus_tag="VVO77_001264"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEU5693278.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEELSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            5874..5947
                     /locus_tag="VVO77_001265"
     tRNA            5874..5947
                     /locus_tag="VVO77_001265"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5908..5910,aa:Arg,seq:tct)
     gene            6113..6238
                     /gene="comC"
                     /locus_tag="VVO77_001266"
     CDS             6113..6238
                     /gene="comC"
                     /locus_tag="VVO77_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HEU5693279.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            6259..7584
                     /locus_tag="VVO77_001267"
     CDS             6259..7584
                     /locus_tag="VVO77_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU5693280.1"
                     /translation="MDLFGFGTVIVHFLIISHNYHLICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIATFLFPLGLYSYFRWIKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDKDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFS
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            7581..8333
                     /locus_tag="VVO77_001268"
     CDS             7581..8333
                     /locus_tag="VVO77_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU5693281.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            8385..8456
                     /locus_tag="VVO77_001269"
     tRNA            8385..8456
                     /locus_tag="VVO77_001269"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:8418..8420,aa:Glu,seq:ttc)
     gene            8462..8535
                     /locus_tag="VVO77_001270"
     tRNA            8462..8535
                     /locus_tag="VVO77_001270"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:8496..8498,aa:Asn,seq:gtt)
     gene            complement(8576..9118)
                     /locus_tag="VVO77_001271"
     CDS             complement(8576..9118)
                     /locus_tag="VVO77_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEU5693282.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            9296..10063
                     /locus_tag="VVO77_001272"
     CDS             9296..10063
                     /locus_tag="VVO77_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HEU5693283.1"
                     /translation="MIGISLIPALYNIIFLSSMWDPYGQLSDLSVAVVNNDKEASYNG
                     NTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSKKTTTLSNI
                     QSTAAYQSLTSEQQTGISDSVSQNSTDSIQSAQSIVALVQGLQGSLENLQNQSSNLST
                     LKNQANQVLPITSTSLIGLSSGLTEIQGAVTSKLVPASQLIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLDKLVSGSNTLTQKSSRLTAGVG"
     gene            10148..10555
                     /locus_tag="VVO77_001273"
     CDS             10148..10555
                     /locus_tag="VVO77_001273"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693284.1"
                     /translation="MADGSGKLAEGGTKLTSGLEDLQTGLASLGQGLGNASDQLKSVS
                     TESKNAEILSNPLNLSKTDNDQVPVNGIAIAPYMISVALFVAAISTNIIFAKLPSGRH
                     PESRWPWLKSRAEINGIIAVLAGILVYGGVLLV"
     gene            complement(10925..13477)
                     /locus_tag="VVO77_001274"
     CDS             complement(10925..13477)
                     /locus_tag="VVO77_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEU5693285.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAIYLTTLLKFGLIGLSTFFSLNKLFQSIPQALKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISITSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTYKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(13539..15161)
                     /locus_tag="VVO77_001275"
     CDS             complement(13539..15161)
                     /locus_tag="VVO77_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU5693286.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            15367..16392
                     /gene="trpS"
                     /locus_tag="VVO77_001276"
     CDS             15367..16392
                     /gene="trpS"
                     /locus_tag="VVO77_001276"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEU5693287.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            16544..18022
                     /gene="guaB"
                     /locus_tag="VVO77_001277"
     CDS             16544..18022
                     /gene="guaB"
                     /locus_tag="VVO77_001277"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEU5693288.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSINEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(18073..19170)
                     /gene="recF"
                     /locus_tag="VVO77_001278"
     CDS             complement(18073..19170)
                     /gene="recF"
                     /locus_tag="VVO77_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEU5693289.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSDQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSKSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGN"
     gene            complement(19173..19541)
                     /gene="yaaA"
                     /locus_tag="VVO77_001279"
     CDS             complement(19173..19541)
                     /gene="yaaA"
                     /locus_tag="VVO77_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEU5693290.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            19700..20950
                     /locus_tag="VVO77_001280"
     CDS             19700..20950
                     /locus_tag="VVO77_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEU5693291.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            20947..22230
                     /locus_tag="VVO77_001281"
     CDS             20947..22230
                     /locus_tag="VVO77_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEU5693292.1"
                     /translation="MTKVVFEEKYYPAVKEMVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEVTSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            22272..23093
                     /locus_tag="VVO77_001282"
     CDS             22272..23093
                     /locus_tag="VVO77_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU5693293.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            23104..23649
                     /gene="pgsA"
                     /locus_tag="VVO77_001283"
     CDS             23104..23649
                     /gene="pgsA"
                     /locus_tag="VVO77_001283"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEU5693294.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            23646..24473
                     /locus_tag="VVO77_001284"
     CDS             23646..24473
                     /locus_tag="VVO77_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEU5693295.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            24458..25297
                     /locus_tag="VVO77_001285"
     CDS             24458..25297
                     /locus_tag="VVO77_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEU5693296.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            25290..26084
                     /locus_tag="VVO77_001286"
     CDS             25290..26084
                     /locus_tag="VVO77_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU5693297.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            26143..26961
                     /gene="mreC"
                     /locus_tag="VVO77_001287"
     CDS             26143..26961
                     /gene="mreC"
                     /locus_tag="VVO77_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEU5693298.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            26961..27455
                     /gene="mreD"
                     /locus_tag="VVO77_001288"
     CDS             26961..27455
                     /gene="mreD"
                     /locus_tag="VVO77_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEU5693299.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            27549..28727
                     /locus_tag="VVO77_001289"
     CDS             27549..28727
                     /locus_tag="VVO77_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEU5693300.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            28951..29730
                     /gene="rpsB"
                     /locus_tag="VVO77_001290"
     CDS             28951..29730
                     /gene="rpsB"
                     /locus_tag="VVO77_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEU5693301.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGHQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            29809..30849
                     /locus_tag="VVO77_001291"
     CDS             29809..30849
                     /locus_tag="VVO77_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEU5693302.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEDGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
BASE COUNT         9861 a         4949 c         6116 g        10077 t
ORIGIN      
        1 acacaaaaag ggataaagtg ctaaccctct aactaagggt tctcagtcaa taattttatt
       61 catttttcgc tcaaaatcat atcgccccat catgacaaca tgctcacaat tactgcattt
      121 tattttgata tctgctccta cacgtgtaat ttcccaacga ttagcctttt taccagtcga
      181 cttgattgta caagcgtgtg attttttcat ctcaacaaaa tttccaactt gatacatact
      241 actctccttt tctttttcga ttatatcata aaagaggcga gccaggctca acctctttca
      301 cttaatttgt acgaactggt gtaatgagct gcatgaagtc ttcgtcagta tctgctggca
      361 caagagtaaa tggacgaaca gctgagataa agctaatagt caccttttcg ctatttaaag
      421 ctttaagaga atcaatcaag taagttgggt tgaaactaat ggtcaaatct tcaccagtaa
      481 cctgatcagt atcgatttct tcgtttactt taccaacttc tggagagtga acatgggcgc
      541 taacaacccc atccttaatt tcaagtttca cagtaccatt ttgagtcgca cttgataaaa
      601 gacgggcacg ctccattgac tggcgtaagt ttaccacatt aaaagtaata gtagtgttaa
      661 agtctgttgg aatcaagcga tctgtatcag gatagtttcc ttctaggaga cgagtataga
      721 agctaatatt ttcgcttcta aagaggattt gattattggc aaagaaaatc tctacagttt
      781 cgatatcatc tgtaaatacc gctgaaaatt cgcgtagaga acggctagga attacgacat
      841 caaaatcatc actatttttt tcaagagtca attttttctg gcttaggcga tgagagtctg
      901 ttgcaactgt ttttaactct ttgtgttgac tcaatacgaa gtggacacct gttaaaatcg
      961 gacgactctc ttgtgtactt gcagcaaagg ctgtttcatt aataattttc ttgagtaatt
     1021 ttgtttcaag tattaaagga gtgcttgctg aaatttcttg gattcgtgga tattgttcgc
     1081 tatcttttcc ttttagggta atttctgatt tgccactggt taaaacaatt tgattttgtt
     1141 caatttcttt aaaatcaaga gttacatcag gtaaactaga tactacattg ataaagaaag
     1201 aagcttcaag aaggatcgaa cctaaagaag taattaacaa accagcatct tcattttttt
     1261 gagaaataaa attttcaatt gaaatttgac catttgaacc aattaaagta ataccttcat
     1321 tggtcacgtc aatttttact gttgataaaa taggaatggc atttttagaa ctaatagctc
     1381 tcttagtagt atttaatgct tgtagaaata aatttttatt aattgaaaaa tgaatcatgg
     1441 attctccttt atttattttt agtattagaa agataatagt aataatagag tctgtgaaat
     1501 ctgtggaaaa cagcctttaa acaagtcata tcaagttttt tagcttgttt aaaaaatgtg
     1561 gataaaaaag ataaaaaact aaaagttatc cacaaattat ttgattttct ttttgattga
     1621 ttcaatttct aaacgtaaat tatcgtcttg atcaatcaaa gattttattt tggcatgggc
     1681 atgaatgact gtggtatgat cttttccccc aaattccttc ccaatttttg gaagactatt
     1741 atctgttagt tctctagata aatacatggc tacttgacgg gccaaaacaa tattttgaag
     1801 gcgtctactt cccttcattt ctttgatact aacaccataa aagttaccaa cttcagtttg
     1861 gattttatca attgggatga cgagcatttg gctaacatct tgtttgcggg ctctaatggc
     1921 ttctgcagca atatcaatag tgatatcctt gatttttttt actctggcaa ttaaagtgat
     1981 gtcgttgatg gctccctcaa gatctcgaac atttgaatca aattgcccag ctaggtattc
     2041 tagagtatca ctttggaaat tgtagcctaa atgttccgtt ttactttgta aaatggcaat
     2101 acgtgtttca aagtcagggg gtgtgatagt ttgtgtcaat ccccaactaa aacgcgtgac
     2161 aagcctctcc tcgagccctt ctagatgttt tggactacga tcactcgtta ggacaatctg
     2221 tttttgcttg tcatgaaggg cgttaaaggt attgaaaaat tcttcctgag ttgcgacttt
     2281 ttttccgctg agtgactgga tatcatcgat taacaaaaga tcaagactac gataggtctt
     2341 tttaaacttt tccatttccc caagtcttag gtgatcaaga aagtcattaa taaagctttc
     2401 ggcagggata tatttaacac gcgcattagg aatatttttt agaatttcat ttccaatagc
     2461 gtttaataag tgagtcttac caaggcctgg tcctccatag ataaaaagag ggttataggt
     2521 cagagccaaa tcttcagaga cagctaaagc ggctgataca gcccaaacat ttccatcccc
     2581 ttgaataaag ttatcaaagg tatacttttc ttttaatccc gtatctgaat aaggaataga
     2641 tactaacttt ggactatagt cataaagagt taaatttgta gcttcttcaa cttgtgagct
     2701 agtcgtatct tgaggtttgg tgaaaatata gtggggagtt atttcagcgt cataaatttc
     2761 aaaaccagct actacaataa tatcttttag ttgtttttcc cagaccattt ccatttcaga
     2821 gcgaggtaga aatatagtgg caacattttc ctctaccttg atgagttcag cttgaatagc
     2881 atagaaatca tacatggatc gagtcagtct ttcttgtgca aattctaata tacgattcca
     2941 aaattgtttt tctttcaatc ctttctcctc ctttactatt taaaagttta atactagaga
     3001 tattttacca tagatagcaa gaattttcca caagctgtga aaaataatcc acaatgttac
     3061 taaactttat ccacaggttg gggataaaag aagaaattat tgatttatta agctttttat
     3121 cgaaaaacat agtggataac cttgtgagat aaaaaaataa aagaacagcc ttatttcagg
     3181 ctgttgataa ttctactata ttcttcttga tttgaaaaag aaataatgat ttttccactg
     3241 tcttttttag atagtttaat ttctacatct aatccgagta gttttcttaa ctgtttttct
     3301 tcattttgta tgaaataatt agttttttgc tgtttctttt gttttttctc tgtcagaaga
     3361 gcttctaact tccttacaga aatatcttct tctataatcc gttgaaagaa atagtcttgt
     3421 tgttccttat ttaacccaac tagggaacgc gcatgggctt gtgatagttt gccattttct
     3481 acttctgaga gaatctgttc tggcaaggaa agtaaacgaa tggagttgct gatatatgga
     3541 cgagacttgc ccatcttatc tgcaatttca gcatgggtga atcctttctc tacgagagat
     3601 tcataggcgc gtgcttcttc tattgggttt aaattttctc tctgtaaatt ttcaataatg
     3661 gactggacca tcatctcttg gtctgaaatc tgtttaacaa cagctgggat agaccgtaga
     3721 ccagctaaaa gtgaagcccg atagcgtctc tctcctgcaa ggatttcata accaataaca
     3781 ggagattgac gaacaataat cggttgaatg accccatttt ctttgataga ctgtgctagt
     3841 tcatctagtt tttctctatc aaattctttt cggggttgat agggattttt ttgtatatct
     3901 gtgatagaaa tcatttcaaa tttttccatg attctacact aacacatctt ttctcttatg
     3961 taaagctttc tttacataga tgtcaattaa gattctaaat cacctgaact cttgttaagt
     4021 ttgatagagg tagtttcttc tttcccgtta cgatagtagg ttatcttaat ggtgtctccg
     4081 atagaatggt tgtaaagagc actttgtaag tctgttgatg aagcaatctc tttgtcatct
     4141 acttttgtaa ttacatcgta tttttcaagg tgaccattgg caggcatatt actttgtacc
     4201 gaacgaacaa ttacaccaga tgtaacatta cttggaatat tgagtcttct gatgtcgctt
     4261 gtactcacat tagataaatt aaccatctgg attcccaaag ctggacgcgt cacttttccg
     4321 tttttttcta actgttcaat aatattgata gcatcatttg caggaattgc gaaaccaaga
     4381 ccttctacag atgttcctcc atttgtagca attttacttg aggtaattcc gataacctgc
     4441 ccttgaatat tgatcagtgg gccgccagag ttacctgggt taatagcagt atcagtttgg
     4501 atggcttttg tagaaatagc ttgtccatct tccgatttta aggatacatt tctattgaga
     4561 ctggatacga taccttgagt gacagtattt gcatattcag aacctaacgg gctaccgatg
     4621 gcaatagcag tttctcctac agttaactta ctagaatcac caaactcagc tactgttgtc
     4681 actttttctg aagagatttt gacgacagca atatcagaga aagtgtcagc tccgacaatt
     4741 tctccaggta ctttagtccc atctgacaat cgaatatcta ctttgctggc gccatttata
     4801 acgtgattgt tggtgacgat gtaagcttct ttatcattct ttttataaat aactccagat
     4861 ccttcactag agattcgctg agaatctgtg tcagtatcat cattgccaaa tacgctattt
     4921 tgtctgtttg ccgaataagt aataacagaa acaacagcat cttttacttt gttaacagcc
     4981 tgtgttgttg aattttcgtt cttataggca gtttgtgtaa tagtactatt gttgttagag
     5041 ttgtttacac tacttttttg agttagttga gttattgaaa aactacccaa ggctccacta
     5101 aaaaagctaa tgacgataac gactaataat tgaaaccatt ttttgtaaaa tgtttttaga
     5161 tgtttcatat ttgcctccat atgtttgaat tactgaaagt ataaactgac tagcttaatt
     5221 ataacttaaa cacaaaagtt ttacacaaac tgtggataac tcttttgaaa ctgtgatttt
     5281 cttaattgaa atctattttt tattttgtga ataagatgtg aaaaaataga gaatatgtta
     5341 gaatagagtc atgaaaatta aagttgtaac agttgggaaa ctgaaagaaa agtatttaaa
     5401 agatggtatc gcagagtatt caaaacgaat ttctagattt gctaagtttg aaatgattga
     5461 gttatcagat gaaaaaacac cagataaggc cagtgaatca gaaaatcaaa agattttaga
     5521 aatagaaggt cagagaattt tatcaaaaat tgctgaccgt gatttcgtta ttgtgttagc
     5581 cattgaaggg aaaactttct tctcagaaga attgagtaag cagttagaag aaacttctat
     5641 aaaaggattt tctactctta cttttattat tgggggaagt ttaggattgt catcatctgt
     5701 aaaaaataga gccaatcttt ctgtcagttt tggtcgccta accttgcctc atcagttaat
     5761 gagactagtt cttgttgaac aaatctatcg cgcttttacg attcagcagg gattccccta
     5821 ccataaatag aaaattgact tttaattgaa tttttggtag aataattgtg ttaggtctca
     5881 tagctcagct ggatagagca ttcgccttct aagcgaacgg tcgcaggttc gaatcctgct
     5941 gggatcaata taatagcaaa gctgggaatt ttcccggctt ttttcttaaa aaagtacact
     6001 ttgggagaaa aaaatgacag ttgagagaat tttatctaaa acgaaattcc attttgtata
     6061 atggtttttg taagttagct tacaagaaaa aaacatttta ggagatttta ttatgaaaaa
     6121 cacagttaaa ttggaacagt ttgtagcttt gaaggaaaaa gacttacaaa agattaaagg
     6181 tggggagatg aggctgtcaa aattcttccg tgattttatt ttacaaagaa aaaagtaatg
     6241 aaataagggg aaagagtaat ggatttattt ggatttggga cagttattgt tcatttttta
     6301 attattagtc acaactacca tttaatttgt aaaggtcaaa taaatagaaa agaattattc
     6361 gtttttggtg cttatacatt actaacagaa atagtatttg attttccctt atatattcta
     6421 tatttagatg ggttagggat tgcaacattt ttatttcctt tgggcctata ttcctatttt
     6481 cgatggataa aacagtatga gagggataga ggactattcc taagtttact actatctctt
     6541 ttatatgaga gcactcataa ctttctgtcc gtaactttct cctctataac aggagataat
     6601 tttgttttac aatatcattt cccattcttt ttcgttgtga cggtgttaac ctattttgtt
     6661 acattaaaaa tcatttacta tttccatttg gaactagcct attttgacaa ggactacctt
     6721 tatcctttct tgaaaaaagt attttttgct ttactattgc tacatattgt atctttcgtt
     6781 tcagatatgg taagtacgat taaacatttg aatagttttg gaagtatttt gtcatctatt
     6841 gtctttatct ctctcctttt gaccttcttt gcaatgaatt ctcataaagt tcaaatggag
     6901 aaagagattg ctttgaagca gaagaaattt gaacagaaac atttacagaa ttacacagat
     6961 gaaattgttg gtctgtataa tgaaatccgt ggttttcgac atgattatgc tggaatgctt
     7021 gtcagcatgc agatggcaat tgacagtggt aatttacagg aaattgacag aatttacaat
     7081 gaagttttag tcaaagcaaa tcataaattg cgttcagata agtacactta ctttgatttg
     7141 aacaacatag aagactcagc tttacgaagt ttggttgctc agtcaattgt ctatgctcga
     7201 aataatggtg tagagtttac actggaagta aaagatacga ttaccaagct tccaattgaa
     7261 ctattggatt tggttcgtat catgagcgtt ttattgaata atgctgtcga aggatcggct
     7321 gatagctata aaaagcagat ggaagtagca gttattaaga tggaaactga aacagttatt
     7381 gtgattcaga attcatgtaa aatgacgatg actccttcag gagatctatt ttccttagga
     7441 ttctccacta agggaagaaa tcgcggagtc ggattaaata atgtgaaaga actactagat
     7501 aagtacaaca atattatttt agaaacagag atggaaggca gtacatttag acaaatcatt
     7561 agatttaaga gggaatttga atgaaagttt taattttaga agatgttatt gaacatcaag
     7621 tgagactaga gagaatattg gatgaaattt cgaaagaatc gaatattcca atatcataca
     7681 agacaacggg aaaagtccgt gaatttgaag aatacattga aaatgatgaa gtaaatcagc
     7741 tttatttcct agatatcgat attcatggaa ttgagaaaaa gggatttgaa gtggctcagc
     7801 tcattcgtca ttacaatcct tacgctatta tcgtctttat cactagtcga tcagagtttg
     7861 cgactctaac ctataaatac caggtatcag ccctagattt tgttgataag gatatcaatg
     7921 atgagatgtt taagaagaga attgagcaaa atatcttcta cacgaagagt atgttacttg
     7981 aaaatgaaga tgttgtagat tatttcgact acaattacaa gggaaatgat ttaaaaattc
     8041 cttaccatga tattttgtat attgaaacaa caggggtatc tcataaattg cgcattattg
     8101 gtaagaattt tgcaaaagag ttttatggta ccatgacaga tattcaggaa aaggacaaac
     8161 atactcagcg attttattct cctcacaagt catttttggt aaatataggc aatatcagag
     8221 aaattgatcg aaaaaactta gaaattgttt tctatgaaga ccatcgttgt cctatttcaa
     8281 gattaaaaat tagaaaatta aaagatattt tagagaaaaa atctcaaaag tgattgacaa
     8341 ttagcaagaa attgatataa tggttatatc tgctacagat agaaggtccg ttggtcaagg
     8401 ggttaagaca ccgccttttc acggcggtaa cacgggttcg aatcccgtac ggactatttt
     8461 atccgccata gctcagttgg tagtagcgca tgactgttaa tcatgatgtc gtaggttcga
     8521 gtcctactgg cggagtatag ataaaaggga acacagctgt gttcctcttt ttgtatcaat
     8581 ttgtatcacc aagcattttc ataaggaagt ctgttatttc ttgagaactt tctttttttc
     8641 catgtgcaat ccaagtttgg cagacaccaa aaagtgcatg agttagatag atgctactat
     8701 attctaattc agtggtattt agattcagtt gcataaatcg cttttgtaaa tctgtactaa
     8761 gcatgatatg aagtttattt cgtaagaaat tttggatttc tttagtccca ttttcagaaa
     8821 gaagggcagc cagaagtggt tctgactcta gatattcaaa aacttctaaa atagcgtctc
     8881 ttttgtgatg agcatgtttt tgaaaaatat attcaaatgt atggaatagc ttgctttgat
     8941 agtgctcaat catatcatac ttatccttat agtgagtata gaagctggaa cgactaattc
     9001 cggctttttc tactaatttg acagtagaaa ttttatcaaa tggctgttcc atcagtaatt
     9061 gtaccatagc attttcaata gttcgctttg tttttaagcg tttgttactt tcttgcatat
     9121 ttcctccttg taaataaatt agactatatg tctaaaaata gattttttat cttgtaattt
     9181 agatttttta atgtataatc tattatatca aaattttaga caatatgttt aaaaaaggag
     9241 aaactatgtt taaagaatgg aaagcaattt aaaaaaaaca acctttatta ttgtcatgat
     9301 cgggatttct cttattccag ctctgtacaa tatcatattt ttgtcatcaa tgtgggatcc
     9361 atatgggcaa ttgtctgact tatctgtggc agttgtaaat aatgataaag aggcttccta
     9421 taatggtaat actatggcaa taggaaaaga catggtgtcc aatttaaaag aaaataaaac
     9481 cttggatttt cattttgtag atgaagagga aggaaagaag ggattggaag atggcgatta
     9541 ctatatggta gtgactttac caagtgattt atctaaaaaa acaactacat tatccaatat
     9601 tcaatcgaca gcagcttatc aatcattgac aagtgagcaa caaactggga taagtgattc
     9661 tgtatctcaa aattcaactg atagtattca atcggctcag tcaattgtag ctttagtaca
     9721 aggtttacag ggaagtttag aaaacttaca aaatcaatct tctaatcttt cgactttaaa
     9781 aaatcaagct aatcaagtat tacctattac ttctacttct ttgataggat tgtcaagtgg
     9841 attaacagag atacaaggag ctgttactag caaattagtt cctgccagtc agttgattgc
     9901 atcaggtgta aacgcatata ctacaggtgt tgataaagtt tctcagggcg caagtcaact
     9961 aagtgaaaaa aatgccacct tgacaggtag tttggataaa ctagtttcag gctcaaacac
    10021 cttgacacaa aaatcttcta gattgacagc aggagttggt taattacaat caggatctgg
    10081 gcaattagca gacaaatcca gtcagttact ttcaggtgct tctccattag agaatagagc
    10141 taataaattg gcagatggat ctgggaaact agcagaaggt ggaacaaagt taacttctgg
    10201 attggaagat ttacagacag gacttgcttc tttaggacaa ggactaggta atgctagtga
    10261 tcaactcaaa tcagtatcaa cagaatctaa aaatgcagag attttgtcaa atccactcaa
    10321 tctttcaaaa acagacaatg atcaagttcc tgtaaatgga atcgcaatag ctccttatat
    10381 gatatcagtt gctctttttg ttgcagcaat atcaacaaat ataatatttg cgaaattgcc
    10441 ttcaggacgt catccagaga gccgttggcc ttggttgaaa tctcgagctg aaataaatgg
    10501 tattatagct gttttggcag gaattttggt atatggagga gttctattgg tttaactgct
    10561 aatcatgaga tgagaatatt tattctcatc atccaaacaa gtttagtatt catgtctatg
    10621 gtgaccactt tagcaacgtg gaatagccgt ataggagctt ttttctcact tattttgctt
    10681 ttactatagt tagcatcaag tgcaggtact tatccacttg ctttgacaaa tgatttcttt
    10741 agatctatta atccctgttt accaatgagc tattcagttt cgggattacg acaaacaatc
    10801 tctatcaaca agtcattttc ctagctgtca tactagctct atttactggt ttaggtatgc
    10861 tagcctatca acataagaaa atggaagaag attaaaaaaa tcgaccgatt aactggtcga
    10921 ttttttatgc cttagatgac tttcgtctgt gattatagat tccaaatagt aagagagaag
    10981 taaaggaaca gattgctcca gtaataaaac cattgggaat gaaggaaagt gtaatagttc
    11041 ctttcccctt gggaatgtca actttcataa atccagtttg agcttgttta atttctattt
    11101 tcttaccatc ttggtaggca gaccaacctt tgtcataagg aatggtgaag aaaatagatg
    11161 tatcttgttg gacatcatat gtagcaaaaa ccttgttttt ataagttgat actgtgacag
    11221 gttgttcttt aattttttga attgcctcgg tgaaagtttt ggtatctaaa cgatagaagg
    11281 taggagattc aaatgatact tgtgaatttc cagggaaact aacattgata ttgaaagttt
    11341 ttttctcttt agtatatcct agattaaaga aggagaagac attatcagtt gtaaaagtct
    11401 ttttttcacc atttacaagg atgtcaacct tcttttgttt atcgttagaa aagtgaaggt
    11461 ttatgaaaga gagataaact tggctgtttt ctggaacttc aatttgatac tggattgctg
    11521 catcttcatt tgaagaactt gtgatactaa tcaaatcatt agtattttct attttttctg
    11581 ttttttcata aggtattgga gaaaaataat caaaattgac gttagcaagt tgatttaaaa
    11641 atgaggcctg attatccaag gtatgttcat tgaacttgac atcattgtaa acagattgac
    11701 tagcaactgc aatcggaaga gagtattgat tttcatatag ggtaagatta tctttttgat
    11761 agatatcttt aaagccatac ttatcaatag gactgtctga gatattgtac tggataccaa
    11821 ataaactatc agccaaaata ctattatttg catatcggag attgagatta gtcccagagg
    11881 atttaaaacc aagtttatct aaagtagagc ttgatgaacg atttcgaaca gatgaaaatt
    11941 gagagattcc attgtagttg aatttcatac tgtcatttcc tgtctgagtt tgtagttttt
    12001 cagtacgagt aaattgattt ccaatatatg ttgagaaaga ttccatagct gggatatctc
    12061 gactataagc acttcgagaa gcaaatcccc attccttagc aattccgtcc atttgagatg
    12121 aagcatttaa actcatttca accagtataa ataaagagat tagaatggca aatagattca
    12181 cagatataaa ctttttgata actgcaagga gtaaaagaga atagacaacc aaaaattcaa
    12241 gagtaagcag aatattcaaa tctgttaaaa aagaataatg cgattttaga tagatggtag
    12301 ctaaaaatcc tgctactaca agaaaaagcg aaactaaaaa attccagact ttaagttctt
    12361 tcagacgctt taagacttct gctgctgtgt aaattaacaa ggtagagaaa atccaagcat
    12421 agcgatgtaa aaacatgttt ggagtatgca tgccttgcca aaataagtca agagcttcta
    12481 tgtaaaagct tgcaattaga aatgcaaaga atattacata tatgagtttc acgtgaaact
    12541 taatagattt cagcgtaaaa aataaaatgg tcaaaataaa gggaaatagt ccaacaaaaa
    12601 tcattgggat ggccccatac tttgttgtgt caaaggaacc aatgaattgc ttagcaaaga
    12661 gatcaagata ccagctactt tcagtttgaa actttgtaac ttcagtcaat ttttccccat
    12721 gtgtctgtaa atcaaataga gtgggaagag tcataatcaa actagccata ccagctaaaa
    12781 aggagataac tatgaaatca agaacagatg attttcgagt cttaaagtcc cacgaaattt
    12841 gacagagata ccagaaaata agaaacaata ctgtcatata tccaaaataa taattttgaa
    12901 taaataagat tgacagactt gtaaagtaca ataggagttt cttttcagtt atcagtagat
    12961 gtaaaccagt tataattaaa ggaatcaaga taaaaacatc tagccaggtt tttatctcta
    13021 attgactgac agtgaaactc atcagagcat aggaagtaga taaggctagt tttaaagcct
    13081 gagggataga ttgaaacaat ttattcaaac taaaaaaggt tgacagacca atcaatccaa
    13141 attttaagag agttgtcaga tagatagcat ctggcatatt cgttagatca aaaaagtaaa
    13201 ccagaggcgc gagaaaacta cccaagtaat aactagatag ggcatagaag tttagcccta
    13261 gaccacttgt aaaggtgtaa aacagactac tatttccatg taggatattt cgtaaggcta
    13321 catcaaaaat aacgtattga tgaaagccat ctcctaatag aggagagttg tcgctattcc
    13381 agtagatacc ttgagataga tatactccag acataatcac tacaggaatg atgaaagaaa
    13441 taaaataggt tcgatatgtt tttaaaaatg atttcatgtt acctcgtaga atgatagaaa
    13501 actcagttgg ttaacccaac tgagttttga agttttattt agtctttcca aagttcttta
    13561 acttttgctt gtacttctgc attttctagg aattcatcgt aggtttcatc gatacggtca
    13621 atgacgccat ttttagataa gacaatgata tggttagcca aagtttgaat aaattcgtgg
    13681 tcatggctgg caaagatgat tgattcttta aagtttttca atccatcatt caagcttgag
    13741 atagattcca agtccaagtg atttgttgga tcatcaagta caaggacatt tgattttaag
    13801 agcatgagtt ttgaaagcat gacacgaact ttttctcccc ctgacaagac atttacaggt
    13861 ttgttaactt catctccaga gaagagcata cggccgagga agccacgtag gaaagtattg
    13921 tcatcttctt ctttacttgc gaattgacgc aaccagtcaa gaattgattc tcctcctgca
    13981 aaatcagctg agttatcttt tggtaggtaa gattgactag ttgtaactcc ccacttgaca
    14041 gttccttcat agtcaatatc tcccatgatt gcacgaatta atgcagtcgt ttgaatatca
    14101 ttttgtccaa taagtgctgt cttatcatct ggacgcaaga tgaaactaat attatccaag
    14161 atagtttcac catcaatctt tacagttaga ttttctactg tcaagagatc attaccaatc
    14221 tcacgttccg ctttaaagtt gataaatgga tatttacgac tagatggtac aatctcttct
    14281 agctcaatct tatcaagcat tttcttacgt gatgttgcct gccttgactt agaagcattg
    14341 gcagagaaac gagcaacgaa ttcttgcaat tgtttaattt tttcttctgc tttagcatta
    14401 cggtctgcta gcaatttagc agcaagctca gaagattcct tccagaagtc gtagtttccg
    14461 acatagagtt tgatttttcc aaagtcaagg tcggccatgt gagtacaaac tttgtttaag
    14521 aagtgacggt cgtgggatac tacgataact gtgttatcaa agtcaatcaa gaagtcttct
    14581 aaccaagtaa tcgattggat atccaaaccg ttagtaggct cgtccaagag aagaacatct
    14641 ggtttaccaa aaagtgcttt ggcgaggaga acctttactt tttcaccgtt ggccaattcg
    14701 ctcatgtttt ggtagtgtaa ttcttctgga atgtttaggt tttgaagtag ttgagaggct
    14761 tcactctctg cttcccaacc tccaagttcg gcaaactctc cttcgagttc ggcagcacga
    14821 accccgtcct cgtctgagaa atcttccttc atgtagatag catctttctc tttcatgatg
    14881 ctataaagtt tttcatttcc catgataacg acatcaatgg cacgttcatc ttcgtagtca
    14941 aagtgatttt gacgaagaac agagagacgt tcatctggac caagagagat gtgaccagta
    15001 gtaggttcga tatctccagc taaaattttt aaaaaggttg attttccggc accattagca
    15061 ccgattaatc cgtaagtatt tccttctgta aatttgatat tgacatcatc aaaaagtttg
    15121 cgatcactaa aacgtagtga aacatcagat actgtaagca atatttttct cctatatgtg
    15181 taatatattt attctactag aaaatacaga aatattcaaa tttttatttg tcaattttgt
    15241 gtaaattata tttacagtat cctttacaca aatctgtaaa aagcaaggct gatttatttt
    15301 gataaattac ggttatttca ttaaaaaaat gctataattg aaaggactat atcgaaggag
    15361 aacaaaatga ctaaacccat tattttaaca ggagaccgtc caacaggaaa attgcatatt
    15421 ggacattatg ttggaagtct caaaaatcga gtattattac aggaagagga taagtatgat
    15481 atgtttgtgt tcttggctga ccaacaagcc ttgacagatc atgccaaaga tcctcaaacc
    15541 attgtagagt ctatcggaaa tgtggctttg gattatcttg cagttggatt ggatccaaat
    15601 aagtcaacta tttttattca aagccagatt ccagagttgg ctgagttgtc tatgtattat
    15661 atgaatctag tttcgttagc acgtttggag cgaaatccaa cagtcaagac agagatttct
    15721 cagaaaggat ttggagaaag cattccgaca ggattcttgg tctatccaat cgctcaagca
    15781 gctgatatca cagctttcaa ggctaattat gttcctgttg ggacagatca gaaaccaatg
    15841 attgagcaaa ctcgtgaaat tgttcgttct tttaacaatg catataactg tgatgtcttg
    15901 gtagagccgg aaggtattta tccagaaaat gagagagcag ggcgtttgcc tggtttagat
    15961 ggaaatgcta aaatgtctaa atcactaaat aatggtattt atttagctga tgatgcggat
    16021 actttgcgta aaaaagtaat gagtatgtat acagatccag atcatatccg cgttgaggat
    16081 ccaggtaaga ttgagggaaa tatggttttc cattatctag atgtttttgg tcgtccagaa
    16141 gatgctcaag aaattgctga tatgaaagaa cgttatcaac gaggtggtct tggtgatgtg
    16201 aagaccaagc gttatctact tgaaatatta gaacgtgaac tgggtcctat tcgtgagcgc
    16261 cgtattgaat ttgctaagga tatgggagaa gtttataata tgattcaaaa aggtagtgaa
    16321 agagcgcgtg aagttgcggg tcaaacccta tctgaggtaa aaggggcaat gggacttcat
    16381 tactttaatt aagtttattt tacaagaaac tatcatttct atctcgaaga aaagatagtt
    16441 ttttatttac ccctgtaaca tttgacaaat ttttatagaa tggtatgata gatacaatat
    16501 aaaaagagtc aagctcaaaa agaaagaaaa gaggaaactt cgaatgtcta attgggacac
    16561 taaatttttg aaaaaaggtt ttacctttga tgatgtattg cttattccag ctgaaagtca
    16621 tgtgttgcct aacgatgcag atttaacaac taaattggca gataatttga ctttaaatat
    16681 cccaattatt accgctgcca tggacacagt tacagagagt caaatggcca ttgctattgc
    16741 tcgtgcaggt ggtctcggag ttatccataa aaacatgtca attgctcaac aagcagacga
    16801 ggttcgtaag gtaaaacgtt ctgaaaatgg agttattatt gatccgttct tcttgacgcc
    16861 tgaacataca attgctgaag cagatgagct tatgggtcgt taccgcatca gtggtgttcc
    16921 agttgttgaa acacttgaaa atcgtaaatt ggttggtatt ttgacaaacc gagatcttcg
    16981 ttttatttca gattataatc aaccaatttc aaaccatatg actagtgaaa atcttgttac
    17041 tgctcctgtg ggtacggatc ttgcaacggc tgagagtatt cttcaagagc atcgtattga
    17101 aaaacttccg ttggtcgatg aagaaggcag tctttctggt ttgatcacta tcaaagatat
    17161 tgaaaaagtt attgagtttc caaatgcggc taaagatgaa tttggtcgtc ttctagttgc
    17221 aggtgcagta ggtgttactt cagatacatt tgaacgtgca gaggctcttt ttgaggcagg
    17281 agcggatgcg attgttattg atactgcaca tggtcattct gcaggtgtct tgcgtaaaat
    17341 tgccgagatt cgtgctcatt tcccagatcg gactttgatt gctggaaata ttgctactgc
    17401 tgaaggtgca cgtgcccttt atgaagcggg tgtagacgtt gttaaggttg gtattggacc
    17461 aggttctatc tgtactactc gtgtgattgc tggtgttggt gttccgcaag taacagctat
    17521 ctacgatgct gcagctgttg cgcgcgaata tggtaaaacg attattgctg acggtgggat
    17581 caagtattct ggagatattg taaaagcact tgctgcaggt ggaaatgctg ttatgcttgg
    17641 atctatgttt gctggaactg atgaagctcc aggcgaaact gaaatcttcc aaggacgtaa
    17701 attcaagact taccgtggta tgggatcaat tgctgctatg aagaaaggtt caagcgaccg
    17761 ttatttccaa ggttctatca atgaagcaaa caagctcgtt ccagaaggaa ttgaaggtcg
    17821 tgttgcttat aaaggagcgg cagctgatat tgttttccaa atgattggtg gtattcgctc
    17881 tggtatgggt tactgtggtg cagctaacct taaagaacta cacgataatg ctcaatttat
    17941 tgaaatgtct ggtgctggtt tgaaagaaag ccatcctcat gatgtgcaaa ttactaatga
    18001 ggcaccaaat tattctatgt aaaaaacaat gaaaagaact ccagtgaaaa caggagttct
    18061 tttacaatgt tgtcaatttc catttacagc agctttacca tcctgaatag tgaagatact
    18121 tagattttct ggtagatttt gaagatggtc taagcttgtt gttgtgataa aggtttggat
    18181 tgattgagaa atcgtttcta ataattttaa ttgtctagtg ttgtcaagtt cactcatcac
    18241 atcgtcaagc agtaatatag gagattctgt ggtaatgctt tccattaatt cgatttctgc
    18301 taattttatc gagaggacga gactacgatg ttgaccttgg cttccgaaac tagcatccat
    18361 cccatttata taaaaagaaa tgtcatctcg atgaggaccg acaccagtat tctttttaaa
    18421 taaatctctg gatttacttt tttctaaagc aattttgaaa gattcggata agttttgttt
    18481 gtcagttata ttgacagaag attgatagga tattgacaac tcttcgatct gattagagag
    18541 ttcaaaatgt ttcttacgcc caaatgattc tagttttttt atgaaatcta agcggtgatt
    18601 cattacacga catccataat caactagctg atcatctaac acagaaagga atgtttcatc
    18661 tattttttga tctgatttta ggtaagtgtt tctttgcttt aggatgtggt tataattggt
    18721 taagtcagat aagtagattg gcttaatttg cccaagttcc atatcgatga attttcgtcg
    18781 aatcgaaggt gctcctttaa ttagttgtaa atcttcagga gcaaataaga caacattcat
    18841 gtgtcctaca taatctgaaa ggcgtgcctg ttttaagtga ttaacttttg ttacacggcc
    18901 tttttgtgtt agttcgattt ctaggggaat ggatccagtt tttttctgaa cgagacctga
    18961 aagatgaagt tgttcctcat caaaatgaat gagattttta tctgttcgag ttcgatgact
    19021 acgcgttaag gctaaaaaat agatagcctc taacatgttt gtttttcctt gtgcattacg
    19081 tcccaaaaag acattcaatt taggattaaa gtctattttc gtttctttgt aattacgaaa
    19141 agtcttgaga gatagatgtt gtagccacat gattatctac cagggaatcg tggagcttgt
    19201 tggcttttag gtgatgaagc aggtttcgat ttgtcttttt taactccctt attcatcttt
    19261 ttgacaagtt tagcgatccg ttctttttca actttatcag cttggtattc atcttgttct
    19321 tcagaagtag gttgtgtcaa caagatgtca atgttcatgt cagggatgtc aactttatcg
    19381 ccaatacgaa gtttttttcc acgacgactc tctaattccc tattaaagta aacagaatgt
    19441 tcagagagaa atgatttaat agctcctccg ctatgtgtaa ttccaagttc tttgagtagt
    19501 gcttggaggg taataaattc ttcaaataat ttgtattcca taattcacct caatctttgg
    19561 tattatacca tattttccta aaaatagtga gagagacagc gagaaatgta agcgattttt
    19621 atttcaaaag tgttacaggg aacaagaaaa tttcaggttt tcgtgatata atagaagtct
    19681 gtatataagg aggtaaatca tggagttagt gcatggaatt tcaacacatt ttatccaatc
    19741 aaaaaagttt aaaacaaaca aaattaccgt gcgttttacc gctccattat cccttgatac
    19801 gattgcaggt cacatgttga gtgcaagtat gctagagact gctaatcaga tgtaccccac
    19861 ttctcaagat ttgaggagac acttggccag tctatacggt acagatatgt caaccaattg
    19921 tttcagaaga gggcaaagcc acattataga attgacattt acctatgttc gtgatgagtt
    19981 tttaagtagg aaaaacgtgc taacctctca gattttggaa cttgtaaaag aaactctttt
    20041 ttcacccgta gtagttgata atgggtttga tccggcctta tttgaaattg agaaaaaaca
    20101 attgctagca agtttagcag ctgatatgga tgattctttt tattttgcac ataaagaatt
    20161 ggataaattg ttttttcatg atgaacgtct tcaattggaa tatagtgatt tacgaaatcg
    20221 tattttagct gaaactccac aaagttctta ctcttgtttc caagaatttt tagccaatga
    20281 tcgaatagat ttctttttcc taggtgattt taatgaggtt gaaattcaaa atgtattaga
    20341 atcatttggc tttaaaggtc gaaaaggaga tgtgaaggtt cagtattgtc aaccttattc
    20401 taatatcctt caggaaggta tggttcggaa aaatgtggga caatccattt tggaattagg
    20461 ttatcattac cgttctaaat atggtgatga acaacattta cccatgattg taatgaatgg
    20521 tttacttggt ggatttgctc actctaagct ctttacaaat gtccgtgaaa atgctggatt
    20581 agcttatacc atttcaagtg agcttgattt atttagtgga ttcttgagga tgtatgctgg
    20641 tatcaatcga gaaaatcgta accaggctcg taaaatgatg aataatcaac tgcttgattt
    20701 aaaaaaaggt tattttacag agtttgagtt aaatcagacc aaggaaatga ttcgttggtc
    20761 gttgttactt tctcaagata atcaatcttc attgattgaa cgtgcttatc aaaatgcctt
    20821 atttggaaaa tcttcagcag actttaaaag ttggattgca aagcttgaac aaattgacaa
    20881 agatgctatt tgtagagtag ctaataatgt gaaactacaa gcgatttact ttatggaagg
    20941 aatagaatga caaaggttgt ttttgaagaa aaatactatc cagctgtaaa agaaatggtt
    21001 tatcgaactc gtttggccaa cggattgaca gttgctcttt tgcctaaaaa ggaatttaaa
    21061 gaggtttacg ggagtgtcac tgtacagttt ggttcggtag atacgtttgt cacagaagtt
    21121 gacggagatg taaaacaata tcctggagga attgctcatt ttcttgaaca taaattattt
    21181 gagagagaag attctagtga tttgatgtcg gcttttacga gtctaggtgc agatagtaat
    21241 gcctttacaa gctttacaaa aacaaactat cttttttcag caacggatta ttttttagaa
    21301 aatttagatt tacttgatga attggtaaca tcagcacact ttactgaagc ttccattttg
    21361 acagagcagg atattattca gcaagaacga gaaatgtacc aagatgatcc agattcgtgt
    21421 ttattctttt caactttagc gaatttgtat cctggtacac ctttagcaac tgatatagtt
    21481 ggaagtgagg agtccatttc ccaaatcaat ctaactaatt tgcaagaaaa ttttacaaag
    21541 ttttacaaac ctgtaaacat gtctctgttt ttagttggta attttgatgt ggagcgagta
    21601 caggactatt ttgaaagcaa agaactgaaa gattcagatt ttcaggaagt agcaagagaa
    21661 aagttgtttt tacagcctgt aaagccaaca gatagtatga gaatggaagt atcttctccc
    21721 aaactagcga ttggagttag aggtaagcga gaagtttctg aagcggattg ctatcgacat
    21781 catattttat taaaattatt gtttgcaatg atgtttggtt ggacttcgga tcgttttcaa
    21841 aaatgttatg aatcaggtaa aattgatgca tccttatctc tggaagttga agtaacaagt
    21901 cgctttcatt ttgtcatgtt gacaatggat acgaaagagc cagttgcttt gtctcatcaa
    21961 tttaggaagg ctattcgtaa ttttacaaag gatttagata ttacagagga acatttagat
    22021 attatcaaaa gagagatgtt tggcgaattt ttcagtagca tgaactctct tgaatttatt
    22081 gcaacgcaat atgatgcttt tgaaaatggt gagacaattt ttgatttgcc gaaaatttta
    22141 caggaaatta ctttagagga tgtccttgat gctggacatc atttaataga tgatggtgac
    22201 atagttgatt ttacaatatt cccatcgtag taacctatta taatagacac tagaaagaag
    22261 ggatgacaag tatgagaaaa aaaacaattg gagaggtttt acgattagct agaatcaatc
    22321 agggattgag tttagatgaa ttgcagaaaa agacagaaat ccagttagat atgttggaag
    22381 caatggaagc agacgatttc gatcaacttc caagtccttt ttacacgcgt tctttcttga
    22441 aaaaatatgc atgggctgtt gagttagatg accaaattgt tttggatgct tatgattctg
    22501 ggagtatgat tacttatgag gaagtagatg ttgatgaaga tgagttgaca ggtcgtagac
    22561 gttcaagtaa gaaaaagaag aaaaaaacat catttttacc tttattttat tttatccttt
    22621 ttgctttatc gattttaatt tttgtgactt attatgtttg gaactatatt caaactcaac
    22681 cagaggagcc ttctctttct aattacagtg tggttcaatc aacaagttca actagctctg
    22741 ttccccactc ctcaagtagt agttcttcta gtatagaatc agctataagt gtatcaggcg
    22801 aaggaaatca tgtagaaatc gcttataaga caagtaagga aacagttaaa ttgcaattgg
    22861 cagtttcaga tgttacaagt tgggtcagtg tttcagaaag cgaacttgag ggcggtgtaa
    22921 ccttatcgcc aaagaagaaa agtgcagaag caacagttgc aactaaaagt cctgtaacaa
    22981 ttacgttagg tgttgtaaaa ggtgttgatt tgacagtaga taatcagact gttgatttat
    23041 cgaaattaac agctcagact ggacaaatca ctgtaacctt tactaaaaat taaggaaaaa
    23101 cgaatgaaaa aagaacaaat tcccaatctc ttaacaatag gtcgaattct ctttatacct
    23161 atttttatct ttattttaac gataggaaat tcgatagaga gtcatatagt tgcagctatt
    23221 atctttgctg ttgccagtat taccgactat ttagatggat atttagctcg taaatggaat
    23281 gtggtcagta attttggtaa atttgcagat cctatggcgg ataagttact agttatgtcg
    23341 gcttttatta tgttgattga gttaggtatg gctccggctt ggattgttgc agtgattatc
    23401 tgtcgtgagt tagctgtgac aggtttaagg cttttattgg ttgaaactgg tggaacaatt
    23461 ttagcagcag caatgcctgg aaaaattaaa acttttagtc agatgtttgc tattattttc
    23521 ttgctattac attggacttt gcttggtcaa gttctacttt atgtagcctt atttttcact
    23581 atctactctg gctatgacta tttcaagggt agtgcctatg tatttaaagg gacatttggt
    23641 tcgaaatgaa atcaataatt gatgtaaaaa atctttcttt tcgctataaa gaaaatcaga
    23701 actactacga tgtgaaggat attacgtttc acgtgaaacg tggagaatgg ctttcgattg
    23761 tagggcataa tggtagtggt aaatcaacta cggttcgatt aattgatggc ttactggaag
    23821 cagaatccgg agagattgta attgatggcc aacgtttgac tgaggaaaat gtttggaata
    23881 tacgtcgtca aatcggtatg gtttttcaaa atccagacaa tcaatttgtt ggagcgactg
    23941 ttgaagatga tgttgctttt ggtttggaaa atcagggact ttctcgtcaa gaaatgaaaa
    24001 agagagtgga agaagctctg gctttagttg gcatgttgga ctttaaaaag agagagccag
    24061 cgcgtctatc aggtggtcaa aagcaacgtg tggccattgc aggtgttgta gccctaagac
    24121 cagctatttt aatcttagat gaagcaacga gtatgttgga tcctgagggg cgtagagaac
    24181 ttattgggac agtaaaagga attcgaaaag actatgatat gacggtcatt tctattaccc
    24241 atgatttgga agaagtcgcc atgagtgatc gcgtattggt catgaaaaaa ggggaaattg
    24301 aatcaactag tagtccaagg gagcttttct ctcgaaatga tttagatcaa attggattag
    24361 acgatccttt tgctaatcaa ttaaaaaaat ctttgagcca gaatggctat gatttacctg
    24421 aaaattattt gacagaaagt gagctagagg ataagctatg ggaattgctc tagaaaatgt
    24481 gaattttaca tatcaagaag gtactccctt agcttcagca gctttgtcgg atgtttcttt
    24541 gacgattgaa gatggctctt atacagcttt aattgggcac acaggtagtg gtaaatcaac
    24601 tattttacaa ctcttaaatg gtttattggt gccaagtcaa gggagtgtga gggtttttga
    24661 taccttaatc acctcgactt ctaaaaataa agatattcgt caaattagaa aacaggttgg
    24721 cttggtattt cagtttgctg aaaatcagat ttttgaagaa acggttttga aggacgttgc
    24781 ttttggaccg caaaattttg gagtttctga agaagatgct gtgaagactg cgcgtgagaa
    24841 actggctctg gttggaattg atgaatcact ttttgatcgt agtccgtttg agctgtcagg
    24901 gggacaaatg agacgtgttg ccattgcagg catacttgcc atggagccag ctatattagt
    24961 cttagatgag ccaacagctg gtctagatcc tctagggaga aaagagttga tgaccctgtt
    25021 caaaaaactc caccagtcag ggatgaccat cgtcttggta acgcatttga tggatgatgt
    25081 tgctgaatat gcaaatcaag tctatgtaat ggaaaaggga cgtttagtaa aggggggcaa
    25141 accaagtgat gtctttcaag acgttgtttt tatggaagaa gttcagttgg gagtacctaa
    25201 aattacggcc ttttgtaaac gattggctga tagaggcgtg tcatttaaac gattaccgat
    25261 taagatagag gagttcaagg agtcgctaaa tggatagtat gattttgggg cgttatatcc
    25321 caggggattc gattgttcac cgattggatc cacgtagcaa attgcttgct atgatgctac
    25381 tgattttgat tgtgttttgg gctaataacc ccttgacgaa tctgattctt tttatagcga
    25441 cagggatatt tattgccttg tcaggagtat ctctttcatt ttttattcag ggcttgaagt
    25501 ctatgttttt cttgattgcc ttcacaacta tttttcaact atttttcatt tctaatggga
    25561 atgttttatt tgagttttcg tttgtgagaa tcacggatta tgctttgcaa caagctggga
    25621 ttattttttg tcgctttgta ttgattattt tcttttcaac tttgttaacc ttaacaacca
    25681 tgcctttaag tttggcatca gctgtcgaag ctttattagc acctttaaag cgtgtgaaag
    25741 ttccagttca tgaaattgga ttgatgctgt ctatgagttt gcgttttgtc ccaaccttga
    25801 tggatgatac gactcggatt atgaatgcac agaaagctcg tggagtggat tttggagaag
    25861 gaagcatcgt tcaaaaagta aaggcgatga ttcccatttt gattcctctt tttgcgacaa
    25921 gtttaaaacg tgcagattcc ttggctatcg ctatggaagc gcgtggctat cagggtggaa
    25981 aaggcagaag tcaataccga caattgaaat ggactctaaa ggatacgctg accattcttg
    26041 ttattctcgt acttggttgt tgtttatttt tcttaaaatc ttagtagctt tcaggaattg
    26101 ataaaaagtt actgtaacag tttttgatat aaaggtaggg atatgaaccg ttttaaaaaa
    26161 tcaaaatatg tcattattgt ttttgtcact gttctgcttg tgtcagctct cttagcgacg
    26221 acttattcaa gtacaattgt gacaaaatta ggagatggaa tctcattggt tgatagagtt
    26281 gtacaaaaac cttttcagtg gtttgattct gtcaaatcag atttggctca tttgacacga
    26341 acatataatg aaaatgaaag tttgaagaaa cagctttacc aattagaagt taaatcaaat
    26401 gaggtggaaa gtttaaagac agaaaatgaa caactgcgcc aattgcttga tatgaagtct
    26461 aaattgcaag ccacaaagac tttagcagca gatgttatta tgcgttctcc ggtatcttgg
    26521 aagcaggagt tgaccttaga tgcaggtaga tcaaaaggtg cttctgagaa catgttagct
    26581 attgcaaatg gtggcttgat tgggagtgtt tcaaaagtag aggagaactc tactatagtc
    26641 aaccttctga caaatacgga aaatgctgat aagatttctg ttaaaattca acatggctct
    26701 actacaattt atggaattat tattggctat gacaaggaaa atgacgttct taaaattagc
    26761 caattaaata gtaatagcga tattagtgcg ggagataagg tgactactgg tggattagga
    26821 aactttaacg ttgctgatat tcctgttggt gaagtggttg ccacaacgca tagtacagac
    26881 tatttgacac gagaagtaac tgttaaattg agtgcagata ctcataatgt agatgtgata
    26941 gaattagtgg ggaattcata atgagacagt tgaagcgagt tggagtattt ttattgcttc
    27001 ctttctttgt tctaattgac gcccatatta gccagcttct gggctcattt ttcccccatg
    27061 tacatttggc tagtcatttt ctttttctat ttctcttatt tgagacgata gaagtatcag
    27121 agtatctcta cctagtctat tgttttgtta taggcttggt ttatgatgtt tactttttcc
    27181 atctaatagg gattacaact ctcttattta tcttattggg agccttcctt cataaattga
    27241 atagtgttat tttgttgaat cgttggacaa gaatgctagc tatgattgtg ctgacattcc
    27301 tgtttgaaat gggtagttat cttttggctt ttatggtagg gttgacagta gatagcatgt
    27361 cgatttttat agtctatagc ttggtaccga cgatgatttt aaatttttta tggattactg
    27421 tttttcaatt tatttttgaa aaatattatc tataagaacg acatataaat gtaacaaagg
    27481 cgtaatattt attaggcctt tttttggtat actagtattg tctttaaaag aaggagtatc
    27541 tacgtaatat gaagaaaaaa atcttagcgt cacttttatt aagtacagta atggtttctc
    27601 aagtagctgt tttaacaact gcgcatgcag aaacgactga tgacaaaatt gctgctcaag
    27661 ataataaaat tagtaactta acagcacaac aacaagaagc ccaaaaacaa gttgaccaaa
    27721 ttcaggagca agtatcagct attcaagctg agcagtctaa cttgcaagct gaaaatgata
    27781 gattacaagc agaatctaag aaactcgagg gtgagattac agaactttct aaaaacattg
    27841 tttctcgtaa ccaatcgttg gaaaaacaag ctcgtagtgc tcaaacaaat ggagccgtaa
    27901 ctagctatat caataccatt gtaaactcaa aatcaattac agaagctatt tcacgtgttg
    27961 ctgcaatgag tgaaatcgta tctgcaaaca acaaaatgtt agaacaacaa aaggcagata
    28021 aaaaagctat ttctgaaaaa caagtagcaa ataatgatgc tatcaatact gtaattgcta
    28081 atcaacaaaa attggctgat gatgctcaag cattgactac gaaacaggca gaactaaaag
    28141 ctgctgaatt aagtcttgct gctgagaaag cgacagctga aggggaaaaa gcaagtctat
    28201 tagagcaaaa agcagcagct gaggcagagg ctcgtgcagc tgcggtagca gaagcagctt
    28261 ataaagaaaa acgagctagc caacaacaat cagtacttgc ttcagcaaac actaacttaa
    28321 cagctcaagt gcaagcagta tctgaatctg cagcagcacc tgtccgtgca aaagttcgtc
    28381 caacatacag tacaaacgct tcaagttatc caattggaga atgtacatgg ggagtaaaaa
    28441 cattggcacc ttgggctgga gactactggg gtaatggagc acagtgggct acaagtgcag
    28501 cagcagcagg tttccgtaca ggttcaacac ctcaagttgg agcaattgca tgttggaatg
    28561 atggtggata tggtcacgta gcggttgtta cagctgttga atcaacaaca cgtatccaag
    28621 tatcagaatc aaattatgca ggtaatcgta caattggaaa tcaccgtgga tggttcaatc
    28681 caacaacaac ttctgaaggt tttgttacat atatttatgc agattaattt acagagggac
    28741 tcgaatagag ccctcttttc aggttttacc gtgacaatcc ctattaaaaa ttatatcaaa
    28801 atagcttgaa aatattggaa aagtatggta gaatgaaaat tgtcgtgtga acgataatac
    28861 tcattcttga tgaattgtga agcagttgcc cttgggtcgt tttgcgagtt gaagtcaaga
    28921 agaggaaaaa aacaaaaagg agaaatactc atggcagtaa tttcaatgaa acaacttctt
    28981 gaggctggtg tacactttgg tcaccaaact cgtcgctgga atcctaagat ggctaagtac
    29041 atctttactg aacgtaacgg aatccacgtt atcgacttgc aacaaactgt aaaatacgct
    29101 gaccaagcat acgacttcat gcgtgatgca gcagctaacg atgcagttgt attgttcgtt
    29161 ggtactaaga aacaagcagc tgatgcagtt gctgaagaag cagtacgttc aggtcaatac
    29221 ttcatcaacc accgttggtt gggtggaact cttacaaact ggggaacaat ccaaaaacgt
    29281 atcgctcgtt tgaaagaaat taaacgtatg gaagaagatg gaactttcga agttcttcct
    29341 aagaaagaag ttgcacttct taacaaacaa cgtgcgcgtc ttgaaaaatt cttgggtggt
    29401 atcgaagata tgcctcgtat cccagatgtg atgtacgtag ttgacccaca taaagagcaa
    29461 atcgctgtta aagaagctaa aaaattggga atcccagttg tagcgatggt tgacaccaat
    29521 actgatccag atgatatcga tgtaatcatc ccagctaacg atgacgctat ccgtgctgtt
    29581 aaattgatca cagctaaatt ggctgacgct attatcgaag gacatcaagg tgaggatgca
    29641 gtagcagttg aagcagaatt tgcagcttca gaaactcaag cagattcaat tgaagaaatc
    29701 gttgaagttg tagaaggtga caacgcttaa tttatacaaa tagtaattac ctaggagggc
    29761 ggggcttagc ccggctctcc tattttcaaa aaatatagga gaattaaaat ggcagaaatt
    29821 acagctaaac ttgtaaaaga gttgcgtgaa aaatctggtg ccggtgttat ggacgctaaa
    29881 aaagcgcttg tagaaacaga cggtgacatc gaaaaagcga ttgaattgct tcgtgaaaaa
    29941 ggtatggcta aggcagctaa gaaagctgac cgtgttgctg cagaaggttt gactggtgtt
    30001 tatgttaacg gtaatgttgc agcagttatt gaagtaaacg ctgaaactga cttcgttgca
    30061 aaaaacgctc aattcgttga attggtaaat actacagcta aagtcattgc tgaaggaaaa
    30121 cctgctaaca atgaagaagc tcttgctttg ataatgcctt caggtgaaac tcttgaagct
    30181 gcatacgtat ctgcaacagc aactatcgga gagaaaatct cattccgtcg ctttgcattg
    30241 attgaaaaaa cagacgcaca acactttgga gcataccaac ataacggtgg acgtatcggt
    30301 gttatttcag ttgttgaaga tggagacgaa gcacttgcta aacaattgtc aatgcacatc
    30361 gcagcgatga aaccaacagt tctttcttac aaagaattgg atgagcaatt cgttaaagat
    30421 gagttggcac aattgaatca cgttatcgac caagacaacg aaagccgtgc aatggttaat
    30481 aaaccagctc ttccacactt gaagtatgga tcaaaagctc aattaactga tgatgttatt
    30541 gctcaagctg aagctgacat caaagctgaa ttggctgcag aaggcaaacc agaaaaaatc
    30601 tgggacaaaa ttattccagg taaaatggat cgcttcatgc ttgataacac taaagttgac
    30661 caagcttaca cacttcttgc acaagtttac atcatggatg acagcaagac agttgaagca
    30721 taccttgaat cagttaacgc ttcggtagtt gagtttgctc gctttgaagt tggtgaaggt
    30781 atcgagaaag ctgcaaacga cttcgaagct gaagttgcag ctacaatggc agcagccttg
    30841 aataactaat aatagaaagg aagcaaattg cttccttttt tgtatagggc ttagattttt
    30901 cctgaaattg ttttttcccc agtctcactc gattagaata attaaaacaa aaagccctat
    30961 aataagggct aagtgcattt aggagactat acttcaaatt cat
//
LOCUS       DAVHLA010000026        29222 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVHLA010000026 DAVHLA010000000
VERSION     DAVHLA010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29222)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29222)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29222
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.026"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(358..1965)
                     /locus_tag="VVO77_001292"
     CDS             complement(358..1965)
                     /locus_tag="VVO77_001292"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEU5693303.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAAAMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDAEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(2355..2942)
                     /locus_tag="VVO77_001293"
     CDS             complement(2355..2942)
                     /locus_tag="VVO77_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEU5693304.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(3070..3381)
                     /locus_tag="VVO77_001294"
                     /pseudo
     CDS             complement(3070..3381)
                     /locus_tag="VVO77_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(3279..3695)
                     /locus_tag="VVO77_001295"
     CDS             complement(3279..3695)
                     /locus_tag="VVO77_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693305.1"
                     /translation="MKVNIVDLHPTQLYLSEKKLQDIQMLYQSAETNQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLKNHI
                     LPLWIGMVSFFGLKSRRRENGFQLGILHYLRIISPL"
     gene            complement(3723..4373)
                     /locus_tag="VVO77_001296"
     CDS             complement(3723..4373)
                     /locus_tag="VVO77_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEU5693306.1"
                     /translation="MKDKQTFLMKGSFALLLFVILGYMVKFYPETLVGFDQSIQTAIR
                     GDLPDYLTILFRSLTHLIDIPVIITWVVIIAFVFYRKRWKIESFFMLGNLALAGLLIV
                     TFKNIYQRPRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDQVWRKIVQI
                     VLGLYLVSVLVSRVYLGVHYPSDVLASFCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(4363..4926)
                     /locus_tag="VVO77_001297"
     CDS             complement(4363..4926)
                     /locus_tag="VVO77_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU5693307.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(5091..5325)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(5379..5882)
                     /locus_tag="VVO77_001298"
     CDS             complement(5379..5882)
                     /locus_tag="VVO77_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEU5693308.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(6075..6905)
                     /locus_tag="VVO77_001299"
     CDS             complement(6075..6905)
                     /locus_tag="VVO77_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU5693309.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(6890..8572)
                     /locus_tag="VVO77_001300"
     CDS             complement(6890..8572)
                     /locus_tag="VVO77_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5693310.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQTAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHCPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNLSIS
                     KGQVQLQNELAKETPALQSLFRLEEVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            complement(8683..8931)
                     /locus_tag="VVO77_001301"
     CDS             complement(8683..8931)
                     /locus_tag="VVO77_001301"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693311.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVS
                     NHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVR"
     gene            complement(8938..9486)
                     /locus_tag="VVO77_001302"
     CDS             complement(8938..9486)
                     /locus_tag="VVO77_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEU5693312.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            complement(9501..10349)
                     /locus_tag="VVO77_001303"
     CDS             complement(9501..10349)
                     /locus_tag="VVO77_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEU5693313.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            10537..11886
                     /gene="trkA"
                     /locus_tag="VVO77_001304"
     CDS             10537..11886
                     /gene="trkA"
                     /locus_tag="VVO77_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEU5693314.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIETKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            11890..13329
                     /locus_tag="VVO77_001305"
     CDS             11890..13329
                     /locus_tag="VVO77_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEU5693315.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSVIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNQTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(13454..15133)
                     /locus_tag="VVO77_001306"
     CDS             complement(13454..15133)
                     /locus_tag="VVO77_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU5693316.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGVIVSGTVAKSLAGNVNRKMPPGKV
                     INDTSAMLAAICGYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QSISFVFLSLILVVDILIYLPFCRAYDRQLLMKEDVASSNDIILEEETSEIMPGELDE
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKNPSKALQFVLEHYQAV"
     gene            complement(15203..16615)
                     /gene="lacG"
                     /locus_tag="VVO77_001307"
     CDS             complement(15203..16615)
                     /gene="lacG"
                     /locus_tag="VVO77_001307"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEU5693317.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGINMWDVYLQE
                     NSPFLPDPASDFYYRYEEDIALAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKYNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGKVGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSDDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAPLNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            complement(16625..16969)
                     /locus_tag="VVO77_001308"
     CDS             complement(16625..16969)
                     /locus_tag="VVO77_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU5693318.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEAYGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            complement(17137..19023)
                     /locus_tag="VVO77_001309"
     CDS             complement(17137..19023)
                     /locus_tag="VVO77_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HEU5693319.1"
                     /translation="MVIRVFDKQKNTYSSFALEELSYYINRVFKTDIELVEEKEADIF
                     VGLVNKEDRRDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRGHDFVP
                     ELRFEDFLDKQLSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEQFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKAFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGQMLWKKTRNYEELIEEYFSALYGENWQSVVEYLEKL
                     SIYSSCDYFNAIGSRQSDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWKNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            complement(19025..20347)
                     /locus_tag="VVO77_001310"
     CDS             complement(19025..20347)
                     /locus_tag="VVO77_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU5693320.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEAFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            20515..21738
                     /locus_tag="VVO77_001311"
     CDS             20515..21738
                     /locus_tag="VVO77_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEU5693321.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            22388..22558
                     /locus_tag="VVO77_001312"
     CDS             22388..22558
                     /locus_tag="VVO77_001312"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU5693322.1"
                     /translation="MTKQVPKFTKDTAQLYTCKWLLYNKVTKMYDHTVVNHSVREYIT
                     DSISTNTIEETG"
     gene            23170..23454
                     /locus_tag="VVO77_001313"
     CDS             23170..23454
                     /locus_tag="VVO77_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693323.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            23447..23695
                     /locus_tag="VVO77_001314"
     CDS             23447..23695
                     /locus_tag="VVO77_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693324.1"
                     /translation="MDKMKPVFQALNKELIQENLTLTIICVDGYVLEYHGLHATQDVD
                     AFYDQNQKINEIIARVGKQFNLNIHEELWLNNHVAKQI"
     gene            23791..24009
                     /locus_tag="VVO77_001315"
     CDS             23791..24009
                     /locus_tag="VVO77_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693325.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LESFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(24377..26701)
                     /gene="pflB"
                     /locus_tag="VVO77_001316"
     CDS             complement(24377..26701)
                     /gene="pflB"
                     /locus_tag="VVO77_001316"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEU5693326.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            27049..28110
                     /gene="dinB"
                     /locus_tag="VVO77_001317"
     CDS             27049..28110
                     /gene="dinB"
                     /locus_tag="VVO77_001317"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEU5693327.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILCAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSIAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITMTGF"
     gene            complement(28257..29102)
                     /locus_tag="VVO77_001318"
     CDS             complement(28257..29102)
                     /locus_tag="VVO77_001318"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEU5693328.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
BASE COUNT         9217 a         6186 c         5097 g         8722 t
ORIGIN      
        1 tggattaaat taaaaaagta taatgtattg aatctataac agtacatctt gactgctaaa
       61 atatttctat aaattaattt gactttcctt atagagatgt tcacatctta tttcaattca
      121 tgatacaatc cagttcctaa aactttgcta gaaattaatt tggctttccg aattaatttg
      181 ttcagatttt atttcatttc aatatactga taaatccatt cactagcaca gggcaagagg
      241 gagtcgctat tgatttcaac ggtagcaggt acatacagag gactcctacc tcagatatac
      301 tgcaatatca tcgtatgcaa aaaacctctg agatttttct caaaggttct gattttgcta
      361 attgctgttc tcaaccgctg cagtaacaaa ggcagtgtag agttcttctg gtcggtttgg
      421 acggcttgac agttcagggt gatactgaca agctacaaag aatttatttt caggaatttc
      481 cacgatttct accaaacgat tgtctggaga aactcctgaa aagacaaaac ctgctgcctc
      541 aaactgctca cggaaggcat tattaaactc ataacggtga cggtgacggc gttgcaccac
      601 ttcttgattg tgataagcag cagcagcctt agagccacgt ttcaacttag acggataaag
      661 tcccaaacga agggttccac ccatatcctc aatatcaatc tgatcacgca tgatatcaat
      721 gatagggtat tttgtttctg gtgcaagctc tgcagaattg gcaccttcaa gacctaaaac
      781 gtgacgagca aactcgatac atgtcaactg cattcccaag cagactccca acattggaac
      841 atcattttca cgcgcatagc ggatggcttg gattttccct tctgtaccac gttgaccaaa
      901 accacctggt acgatgatcc cgtccgcatc agacaagagt tctgctacat tctctgctgt
      961 cacatcattg gcattgaccc aattgatttt aacttctgca tcattgacat agccagagtg
     1021 tttcaaggct tcgaccactg agatataggc atcttgcaac tccacatact taccaacaag
     1081 ggaaatctta acttgtttct tgaggttcat gaccttgtcc accatggctg accattctgt
     1141 catagccgct gctggtgcgt ctaatttcaa atgatcacaa acaatttggt ccatcccttg
     1201 tgcctgcaag ttcagtggaa tttggtaaag gtgttcaaca tccaacgatt cgataacggc
     1261 ttctggtgcc acatcacaga actgggccag tttattttta attccttgac cagctggctc
     1321 ttctgtacga ataaccaaca tatttggttg gattcccaag ccacgcaatt ctttgacaga
     1381 gtgttgggtt ggtttggttt tcatttcacc agcagccttg aggtaaggaa gcaaggttgt
     1441 atggatatac atgacattat ccgcacccac atctgccttc atctgacgaa gagcctctag
     1501 gaatggcaag gactcgatat ctcctactgt tccaccaacc tctgtgataa tgacatcaga
     1561 gtcggtcgtt agagcggcac gcttgatttt ttctttcaaa gcatctgtga tatgaggaat
     1621 gacttgaaca gttgccccaa ggtattctcc acggcgttct ttacgaagaa cttcactgta
     1681 aattttccca gttgtcacgt tggaatattt gttgagattg atatcgatga aacgttcata
     1741 gtgacccaag tccaaatctg tctcagctcc gtcatctgtc acaaaaactt ccccgtgctg
     1801 gtaaggactc atggttcccg gatcaatatt gatataaggg tcaaactttt gaatggttac
     1861 tttgagacca cgatttttca agagacggcc tagactcgct gccacaatcc ctttcccaat
     1921 agacgatacc acaccaccag ttacaaaaat atatttcgta gacatagatt cctctttcta
     1981 aaatgctcaa ggtcttgtta actacgaggg gatatagaaa acaagaccct actaataaga
     2041 ataatctggg acgactgcac cagattcaca actaatactc ttcgaaaatc tcttcaaacc
     2101 gcgtcaacgt cgccttgccg tagatatgtg ttcctgactt tgtcagtctt atctacaacc
     2161 tcaaaacagt gttttgagca gcctacggct agtttcctag cttgctcttt gattttcatt
     2221 gagtataaaa tacaagaaga taacttcttg aaaaaacaaa aatagctccc taagaactag
     2281 ggagccccga cctctaaaag aggtgcccaa acaatatgat acctaaaaat aggataattg
     2341 tcaatagcta actcttattc ctcgctggtt tcagcgtcgt catctgaaaa ctcgtcgtcg
     2401 tcttcgttga gatccacatc ttctcccaag tcatctggag cgatttcgtt gatttctgca
     2461 tcataagctt ccacttcatt tttttcatca tctggatttt catcatcgta tgaaagagct
     2521 ggatctgctt cgtatgcatc ttcgtcttct ggatcatctg cattgtagtc aatggcatct
     2581 gaatcaccat ccataaaggc attgacacgt tttttcttag cttttggtgc tacttcatcg
     2641 tcgtcatttt cttcaagagc gatgatttct tcgtcgattt cgtccacacc ataccatgaa
     2701 cgaagacccc atttgttgtc cccaagtgag atgaagctac cgtcaaagtt caactctgtg
     2761 tagaacagag gcaaagcttc gcggatatcg ctgtttgatg ttccaaggta gttttgaatt
     2821 tcgtttacaa gatcgctaaa atgcatctca tgatcgcgac cacgaagttc taatatagca
     2881 cgcgctacct caatcataga tagttcactt ttttcttgcc cagcaaatac ttctaattcc
     2941 aaagcgtttc tcctcattta tactactatc gccagagcga acagactctg acctcatttt
     3001 atcatttact ctttatttta cgataatttt gcggaatagt caaaggttaa gggggagaaa
     3061 gtggcaggat tagactaatt ccaatataaa actccttcct ttttctgttg ctccattttc
     3121 cacaaatcca agcgacttga aacacctcct agaagcatga ttgtaggtgt agatttcctt
     3181 gactctcaat tctttccatc cttttactcg agccaattca atcaaagcac ttagaatctt
     3241 ttttccaagt cctcgatgtt ggtaagcgga attcccaatc acaatgggga gattatcctg
     3301 agatagtgta atatccccaa ttggaaacca ttctcccttc tccttgactt caatccaaaa
     3361 aagctcacca tgccgatcca aagaggtaag atatgatttt ttaaatcaaa aacagagtaa
     3421 atctttcttt cctcgcaagc ttgcgcatag agatgatata gttcatcacc accatctcta
     3481 tcccactcag cagaaatcgt atcccgacct gccaataaag cctgataagc cctgtgatgc
     3541 ccatctgtaa tcagcaaaca atctccaaag gcaagaatac tgattggatc gacttggttt
     3601 gtttctgccg actggtaaag catctgaata tcttgcaact tcttttctga taaatatagt
     3661 tgagtcggat gaagatctac tatattgact ttcatttctt tctcctaaag ggaattcgat
     3721 actcacttct gtttgccttt aaatcgccat tggaagcgga gcttgtcata gaagggaaac
     3781 tcgataaaca agactcccaa acccacacag aaactggcaa gaacatctga tgggtagtga
     3841 actcccagat agactcttga taccagcaca ctgactaggt agaggccaag gacgatttgt
     3901 acgatttttc tccagacctg atctttaatc cgctgactaa gaataacaat caaagtccct
     3961 accatcagcg ttacagctag agaatgccca cttgggaagg aaaatccctt ctcctccacc
     4021 agatgtaaga tagctggtcg tgggcgctgg tagatatttt taaaggtcac gattaaaaga
     4081 cctgccaaag ccagatttcc cagcatgaag aaactttcta tcttccatcg cttacgataa
     4141 aagacaaaag ctataatgac aacccaagtg ataatcactg gaatatcaat cagatgtgtg
     4201 agggatcgaa aaagaatagt caaataatct ggtaagtctc ctcgaatggc agtctgaatc
     4261 gattggtcaa aaccgaccag cgtttcaggg taaaatttga ccatatagcc aagaataacg
     4321 aaaagtaaaa gggcaaaact gcccttcatt aaaaatgttt gtttatcttt catagtgttt
     4381 taaggttggt ttcaaaagga cgtacaacaa ccagaatgaa acggaaaaga ttacaccctc
     4441 aatcaagtta aaaggtaata ccatggtcat taggtagttg gaaagtccca aaatttttcc
     4501 aatatcaaag ttagcaaact tagcgtacaa aggaacagca taaacatagt tgagaaccaa
     4561 catggccaag gttaaaccaa cagttccagc tagagagcct agtaggaaac gaagggttgt
     4621 ccgttccttt ttccaaatca aagcaaatac gatgacaaaa actcccaaag ctacgatatt
     4681 catcggcaaa ccaatgtaag tattcactcc ttggctgtta agaagcaatt tcaatagtga
     4741 gcgaagcaag agcactccta gagcagcagg caaatccatg accaccagac ccacaaggac
     4801 tggcaagata ctaaattcga tcttgaggaa agatgccgct ggtaaaagcg gaaagtcaaa
     4861 gtacatcagc acaaatgaga tggctgatag aattgcaatg gtcgaaagtc gacgtgtgtt
     4921 tgtcataaca ggttcctcca attttctata aaatcagaag aagttggaaa ggattcctct
     4981 atctattctc actttttata tcccaaaagt tccctcttac tctattaaag aaaaacaaag
     5041 caagtggtta caatccggct ataaatctat caaaacagac aaagctattc tttcgtcttc
     5101 tcccatccag actatactgt cggttgtgga atctcaccac atcagcttgc gctcgcggac
     5161 ttctttaaag agaaggaaat agagattttt cttttagact aggcgacaag ctgtaggcat
     5221 aacttctggt taggcaaagc ttgtcaacaa agtataaaag gaaaagatca tttcctagtt
     5281 aaagtcaccg ccggtcggga atcacaccct gccctgaaga ctcttttatc ataacaaaaa
     5341 acgcttgcaa gcgcaagcat tttgttcatt ttcatttttt atttcaattt atccacttca
     5401 taggtatgga cgagctcaag acctgcaaag ttctgctggc gaagagcctc atagacaatc
     5461 atgcagacgg tattagacac attgagactg cggacatgtt catcattcat gggaatacgg
     5521 agagccttct caggatgttc tcgcataaaa tcttcaggta agcccttgtc ttcacgtcca
     5581 aagagaaaat aatggtcctc gtcagtcgat aaatccacct cagaatagac tttttccgcg
     5641 aatttcgaaa tcagatagag ttttcccttc atctgagata tgaaatcttc caaactctcg
     5701 taaaaataaa tctctagctt atcccagtaa tccaatccag cccgcttcat cttgcggtca
     5761 tcaataggaa agcccatagg cttgatgatg tggaggggag aattggtcgc agcgcaagta
     5821 cgcgcgatat tgcccgtatt ttgtggaatt tgaggttcaa ataatacaat gtgatttgtc
     5881 atgacttgct tcctttcacc attgcaaaaa aatagccaca ctgcccggag tcaagctcag
     5941 caaacagcgt ggttaaggca tcgttaactt acctcacaac aggtttgaag taaatcagcg
     6001 aaactacttt cttagtataa cactttcaga atcattgtca atagaaatga cttgattttt
     6061 tcaatttttt caagctattt ccaagggttg taaaatcgtc cctgattctg caagataagt
     6121 agtaaactaa ctactaaaaa caaggttgcc aagagcaagg taatatagtc tccttttttc
     6181 aaggcctgat aactatacca tgtgcgtttt ttctctttcc caaagcggcg aagctccatg
     6241 gcagtcgcaa tggtatcaat gcgttctagc gagctaaaaa tcaagggcgt aataatgagc
     6301 agattgcctt tgattcgttg cataagagaa gctttcttgg ataattccat cccacgcgcc
     6361 tcctgagaca tcttgatagt aaagaattct tcctgcaaat ctggaatata gcgcaaggtc
     6421 aggctgacag aataagcaat cttatagggc acaccaattt gatttaaact ggaagcaaac
     6481 tgactaggat gggttgtcat caaaaagata atagccagag gaatggtgca aagatactta
     6541 atggccaaat ttagcagata aaagagctcc tggctggtta gagtgtagac accgattccc
     6601 tgccaaatca cacttctctc tccataaagt ccaaccccat actcgggaga aaagagatag
     6661 accatcaaaa cgtttaaaac ggcaaatacc gtcgcaaaaa cggctacaaa ggaaacatct
     6721 ttaaagcgaa tttctgataa atagaggaga aagactgaaa agatggcaat cagcaagagc
     6781 attctggtat catagctaat catggccgcc aatgatacca gaatgaaaaa gagaagtttc
     6841 ccagctcctg acaagcgatg aatcacagta tctctatgct ggtaaccgat taatttagct
     6901 tgcatccctc tctcctttct ttgtaaaatg ccgttaaatc cagtggatcc acatctagtt
     6961 tcttagccaa gttaaagatg gaggtttctt ttagattggc ttttactaac agctcaggat
     7021 cgctcaacag actggctgga acagtatcgg caatcaattc tccatccacc atgacaagga
     7081 cccggtctga ataatccagc atcaattgca tatcatgggt aatcatgaca atggtatgcc
     7141 ctttttgatg taactcttcg agaaattcca taatctcagt atagttcttc tgatcttgac
     7201 ctgcagtcgg ttcatctagg agaataattt cagctcctaa gaccaaaatt gaagcaatgg
     7261 tgacacgttt tttctgacca aatgacaggg cagaaatagg ccaattacgg aattcataaa
     7321 gtccacagat tttcaaggtt tcatatactc tcgtttcaat ttccttctca tccacacctc
     7381 gcaaacggag ccctagagcc acctcatcaa aaatcatatt ggttgaaatc atttgattag
     7441 gattttgtag cacatatcct actcgttccg cccgctctgc aacagaatcg ccttttatat
     7501 cctgtttttc ccaaagatag cgtccttccg tctgaataaa gctacttata gccttggcta
     7561 gagttgattt ccctgctcca ttttttccga caatagcaat cttttcaccc tttttaatat
     7621 ctaaatgtag ggattttaaa atcggtctat catcataaga aaaagatact tcctctagtc
     7681 taaagagtga ctgcaatgct ggggtttctt ttgccagttc attctgcaac tgaacctgac
     7741 cttttgagat agacaagtta tccagattcg ctaattgttc ttccttgact aaatccacac
     7801 ccaattgacg gagagtggtg agataaaggg gttcgcgaat tccattttgg gtcaacaaat
     7861 cagtcgccag taactggtca gggctcccat taaaaaggat acgaccatcg tttatcaaga
     7921 caatccgatc cacagggcaa tgcagaacat cctccaaacg gtgctcgata ataagggtcg
     7981 tcgtcccctc ctccttatga atctggtcaa tcaattcgat aatatcctga cctgacttgg
     8041 gatcaagatt ggcgagtggc tcatcaaaca agagaatcgg actttcatca atcaagacac
     8101 cagccagact gactcgctgc ttttgtccac ctgacaaatc ctgagggcgc tgatccagta
     8161 aaggaagaag gtccagcttt tcagcccatt tataaacacg acctttcatc tcatctaggg
     8221 ctgtcacatc attttccaga gcaaacgcca aatcttctgc cacagacaag ccaataaact
     8281 gcccatctgt atcctgcaaa actgtgctaa ccagatgaga cttatcatag atgctcatat
     8341 caaaggctgt ttgacccttt atcaaaaatt ctccatatgt ctgacccttg taaatattgg
     8401 gaataatccc attcaaacac tgacccaagg tagatttacc tgatccagat ggtccaacaa
     8461 ttaagacttt ctctcccttg taaatggtca agtctatccc ttgcaaggtc ggttcttgtt
     8521 gtgtttcata ccggaaagag aaatccttcc actcaattat agcttctttc atcttactct
     8581 cttcattcgc ttcttagact tctattttat cataaatcaa gcccttcttg cagtctctcc
     8641 tattaaaatc ttagcgccaa aaagattcct atcctagctt acttacctaa ctaatctata
     8701 aacatcgaaa aagactagtt gcccagcctt ccccatcatt ttatactctt cgaaaatctc
     8761 ttcaaaccac gtcagcttcg ccttgccgta ggtatggtta ctgacttcgt cagtttcatc
     8821 tacaacctca aaaccatgtt ttgagctgac ttcgtcagtt ctatccacaa tttcaaaaca
     8881 ctgttttgag caacctgcgg ctaacttcct agtttgctct ttgattttca ttgagtatta
     8941 gtcctttttc aaacttcctg cacgagtttg ggttcctgca taggcaagta agagaagagt
     9001 tcctgcaata gctacagata caccattggc aattcccgca acaatccctt gtgcaaatac
     9061 tttttctgcc gcttcttgat aaatcacaac atctccaagt ggtgccaaga caccccaaac
     9121 aagggcattt gcaagtagtt gaatgaggtt aaaaataaga atatctttcc agtcaaaaac
     9181 accattgatc acgcgaacgt actttctaaa aagtcccaca actaaaccaa agagtccgct
     9241 agcgataatc caagtccacc atagaccata accagcaaga gagtccttga ttgcatgacc
     9301 aatcaacccg acaagcaaac cgataatcgg tccaaaaata atagaaagta gcgcttgtac
     9361 cgcatactga agctggatgc ttgtatttgg aacaggggtt ggaatgttga tcatcccgat
     9421 gacgacaaag agggcagcgc caattccgac agcaacaact tgtttaattg taaatttaat
     9481 ttccatacta ttctcctatt ttatccttct attttcttta tttcaatggt ccaagatgaa
     9541 ccgacaccta cattataggc cttggcaaag gaaccttggt tgatagccaa acctaaacga
     9601 tagagagagt tgatgtaaag gatgggttgc ccaattctca catctgcaaa tgatttgcca
     9661 tagacaacct gattttgata gaccagcata tcagcatgat agatggtcac ttcaaaacga
     9721 tcaccaaatt ctggttccag cttgtaaaat tcttcccgtg tgatagaggt ccaaagcgaa
     9781 ccgaaacgca catccagaat atcaatggct cccttcacca gatgatcttc tatgatggtc
     9841 gctacgactg gaagctctac aatctgttcc acactgagct ctggccctac ttcctcaaaa
     9901 gtaatgtgac cactggccag tttagcacca gtataggcat agacatcacg accgtggaag
     9961 gtataagaat gctctgtgtt ttgacgccta ttggccacct cagaaatctc acgaatggct
    10021 acaatgccaa cgtgtttctt gataaaggaa agcgtcccat tatctggcgt gacaatgtat
    10081 tgattttttg cagtcttggc aactacactc ttacgtttcg aaccgacacc tggatcgaca
    10141 accgatacaa acgtcgttcc ctcaggccag taatccaccg tctgaaagag acgatagctc
    10201 ccctcaaaaa tattataagg cgtgatatcg tgcgtcaagt gatggatttt taaggttgga
    10261 gactcttcta aagccactcc aatcatagcc gataccgcac catcaaccag accaaagtct
    10321 gattgtaata ccagtaaatt attattcatt ttatctcctt gtatatcctt tatcatacca
    10381 tatttcagag aaagtcgcta atagctattt caattggtta gggtatagtt ttaccttata
    10441 gcgaattttc actaaaagct cttgttatta gctagtaggt gcattttttc ttgaaaaagg
    10501 gtatgatagt tacatcatga aaaagtaggt tttattatga aaattatcct tgtcggaggg
    10561 ggaaaagttg gttttgccct ctgtcgctcc ttggttgcag aaaagcatga tgttttgctg
    10621 attgagcaag acgaagctgt tctcaatcat attgtcagtc gctttgatat cattggtatc
    10681 cttggtaacg gggccgattt tgccattctt gagcaagcca gcgtccaaga ttgtgatatc
    10741 tttatcgccc tgactgagca cgatgaagtc aacatgattg cagcagttct agccaagaaa
    10801 atgggagcta aagaaactat cgttcgggtg cggaaccctg aatattctaa ctcttatttc
    10861 aaggaaaaga atattctcgg tttttctctt atcgttaatc ctgagctctt ggctgcccgc
    10921 gctatcgcga atatcattga cttccccaac gccctgtctg tcgaacgctt tgctggtgga
    10981 cgcgttagcc tcatggaatt tgtcgtcaag tccaccagcg gtctttgcca aatgcccatt
    11041 tctgattttc gtaaaaaatt tggtaatgtc attgtctgtg cgatagagag ggatcatcaa
    11101 attatcattc caagcggtga catgactgta caggataaag atagaatctt tgtcactggt
    11161 aaccgtgtcg atatgatact cttccataat tattttaaat cacgcgccgt gaagagcctt
    11221 ctcatcgttg gagctggtag aattgcctat tatctattag gtatcctcaa agatagtcgt
    11281 atcgaaacca aggttattga aatcaatcct gaaatcgcta gcttctttag cgagaaattc
    11341 ccaaatctct acatcgttca aggagatgga accgcaaaag atatcctgct ggaagaaagt
    11401 gctcaacact atgatgccgt tgcgactcta acaggagtcg atgaggaaaa tctgattaca
    11461 tctatgttcc ttgacagggt aggtgtacag aaaaatatta ctaaggtcaa tcgtaccagt
    11521 ctcctcgaga ttatcaatgc gcctgatttt tcaagtatca tcacacctaa aagcatcgct
    11581 gtagatacga ttatgcactt tattcgtggt cgagttaatg cccagtattc agaccttcaa
    11641 gccatgcacc atctagccaa tggccaaatc gaaaccctgc aattccatat caaggaagcc
    11701 aataaaatga ctgccaaacc tctttctcaa ctgaaattga aaaaaggggt tcttattgca
    11761 gccattattc gaaagggcaa gactattttc ccaactgggg aggatatgtt ggaagttgga
    11821 gacaagctcc tagtaacaac cttgttgcca aacatcacca agatttatga cttgattgcg
    11881 aggtaagaaa tgaataaaag tatgattcgt tacctccttt caaagttact tttgattgaa
    11941 gctgttctcc tcttggttcc tgtggctatc gctgtctatt accgtgaatc gagccaagtc
    12001 tttacagccc tcttttcgac catagggatt ctcgtattgt taggcggttc agggagttta
    12061 cagaagccaa aaaatcaacg gatttatgcc aaggagggag tcttgatcgt tgccctctgt
    12121 tggatccttt ggtctttctt tggtggtctc ccctttgtct tttctgggca aatccctagc
    12181 gttattgatg ccttttttga aattagttct gggtttacaa ctactggagc aagtattttg
    12241 aacgacgttt cggttctcag ccgttccctc ctcttctggc gaagttttac ccacttgatt
    12301 ggagggatgg gagtgcttgt ttttgcactt gctattatgg acaatgccaa aaatagccac
    12361 ctagaggtga tgaaggctga ggttccaggt cctgtttttg gcaaggttgt atccaaacta
    12421 aaaaacactg cccagattct ctatctcctt tatctagctc tcttctccct ctttgtcatc
    12481 atctattatc tagctggtat gcctctctac gatagttttg tcattgctat ggggacagcg
    12541 ggaactggag gctttaccgt ctataacgac ggaattgccc actatggcag ctcactgatt
    12601 acctatctgg tcagtatcgg agttctggtt tttggggtaa atttcaacct ctactactac
    12661 ctcatgctcc gtcgcatcaa ggccttcttt ggtgacgaag aacttcgggc ttacttggtc
    12721 attgtactgg tttctacagg cttgattagc ctcaacaccc tctacctcta cccagggttt
    12781 tcaaagagct ttgaaatgac cttcttccag gtttccaaca tcattacaac aactggtttt
    12841 ggatatggag atattaccaa ctggcccctc ttctcccagt ttatcctcct tttcctcatg
    12901 gcaatcggtg gctctgctgg atcaactgca ggtggactca agattattcg aggcctcatc
    12961 ctttcaaaaa ttgccaaaaa ccaaattttg tcaatcctat cgccccaccg tgttttgact
    13021 ctccatgtga atcaaacggt gattgataaa gatacccagc ataagattct caagtacttt
    13081 gtcatctatg ctatgatttt gctagcgctt atctttattg tcagcctaga tagcaatgat
    13141 tttctggtcg tgaccagcgc tgtctttagc tgtttcaata atatcgggcc tattctagga
    13201 accacttcta gtttctcaat ctttagtccc atctcaaaaa ttctcctctc ctttgcaatg
    13261 attgcagggc gcttggagat ttacccaatc ctccttctct ttatgaaaag aacttggtct
    13321 aagagataaa atacaaaatc cctcttttta caattgtgaa agagggattt ttatattaaa
    13381 aagggggaac gtttttaaat ccaagcctgt ctgtaagcaa agttcttact caaataaaag
    13441 atggaaaaac ttactacaca gcttggtaat gctccaatac aaattgtaag gctttacttg
    13501 gattctttgt taaatgaata tattccattc ctctggtagc aactatctga atacctaatc
    13561 tttctgcatc caccttcatc tctctataat aactccgaac ttgtggagcc agaataatta
    13621 aatcataaac acccataata tcataatgag ctccgtacgc tcctgaattc gcaatcactc
    13681 taacttctgc taattgagcg ccctcgttaa ttgcattggc taattgcgca cttgttccag
    13741 accctgcaca aagaaccagt actttcaact ccttactttt tatttcatct aactcaccag
    13801 gcattatttc acttgtctcc tcctctaaaa taatatcatt tgagcttgca acatcttctt
    13861 tcatcagtaa ctgtctatca tacgctctac agaatggcaa ataaatcaat atgtcgacaa
    13921 ctaaaatcaa agataaaaat acaaaggaga tagattgaaa attcgttcca attaacaatc
    13981 ccaagggacc aggaaaggcc caaggtaact ggatataaaa tccattcatt ccaaagaaat
    14041 caataaagac ctttcctaga aatacattca ctggtggagt catcaaaaaa ggtacaaaaa
    14101 gatagggatt caaaataact ggcataccaa atagaagagg ttcattcact gcaaataaaa
    14161 caggagtaat tgtagcttta cctaccgatt ttaattgttt agaccgcata aagaaaatca
    14221 aaataaatgg tacaacaaag gtagcccccg ttcctccgat agcagcgata taatttccga
    14281 aattaggcgt taaagaatga taaggaaact gcccatttgc aagaagttga gcattctctt
    14341 ccatattgct cagttgtaaa gctgtaacag caggtaagac aatagatggt ccatgaattc
    14401 caacaaacca aagcaaagcg cacataaacc aaatcaacat catagcagga tatgattctg
    14461 cccccttaaa aataggagtc aatagttgtt gaaatacttg ggcaaaagga acatctaaac
    14521 taaaccgaga tacaatatct aacaaaccac taataagtaa aacaaaagaa aaaggaaaaa
    14581 tatctctaaa agcttgtgat atagccccag gaacttcctt aggtaaatga atagtaatgt
    14641 ctcgcttaat acagaatcgg taaacattta cagtaataaa ggcactgaca aacgaagtta
    14701 tcaatccttg agatcctaaa tagtttgtcg acaaacttgt agatcccgtt ttctcatcaa
    14761 ctacaagcgt tacagttaat acaagatagc cacatatggc cgccaacatt gcagaagtat
    14821 catttattac ctttccagga ggcatttttc tattaacatt tccagccaat gactttgcaa
    14881 ctgtccctga aacaataaca cccaaaactc ccatggttag catatacact ttcctcatcc
    14941 aggcaatagc tggactcggt aactctactc cgaaattttt aggaatcata ataataatca
    15001 tcaaaaagct tgaaaacata attaaaggca tagtagcaat gaatccatct ttaatagcca
    15061 tcatataatt attagtagaa attttttcaa atttcccttg ttgcttttca atggcagcga
    15121 ctaacttatc cataaaaact cctcctgtaa aaaatttaag ctcatagtta aaatatatta
    15181 aacatcagtc aaatcgctaa ccttaattcc gttttagccc ttttacccaa agagcacttt
    15241 tcttaatata tctcttctgt gtttcataat caacaaagaa aagaccatat cgcttattgt
    15301 agccattcgc ccaagaaaat tgatcttgca aagaccatat aaaatagcct tgaatattga
    15361 ctcccctatc tcgagcctct aaaactttgt gtaaatgttg ctcaatataa cggattcttt
    15421 tactgtcatc aataatatca ttctcgccct ctggcttaac ctctttaagg gctgtaccat
    15481 tttcagttaa ataaatgacc ggatgttgag gatattcttc tttgatacga agcaacatat
    15541 caaataaccc ttgaggataa atattccaat cccaatctgt tgtcggaata ccaggctttt
    15601 ttacaaattc acctagagca tttaatttaa aagaagactg tccttttatt cctgttgaat
    15661 taaattcttg tctattttca cctttgtatt cacgaataaa ttctgaacga taataattca
    15721 tcccaaacat cgtattaaga ggtgcagctc ttttcataat ttctaaatca ccatcttcaa
    15781 taataaagct agaattatta gcttccaata tttgattcaa gtgaaaaagc gtgtcatcac
    15841 tgtagtagcc caaaaaagtt ccatctaata gaaatttatt attataaaca tcataccgtt
    15901 tagctgccaa aatattttct ttttgcccat caataggata gcctggcttt aaagcatgaa
    15961 tacaacctac ctttccctca atccctaatt gatgaaattc gaggactgca agagcatgcg
    16021 ccaacaacat gttatgattt gcttgaattg cttcagataa ttgaaaatgg tgattcggag
    16081 gaaactgacc tcctatgtat tggcctgcag caagagacat cagttcattg attgtaaacc
    16141 aatgcttgac ttctgtaaat tcttggaaac aaaagcgagc atatcgtatg aaacgatcaa
    16201 tattctctct attcaaccaa tcccctgttt ctaacatttt ctgaggcgaa tcaaaatgat
    16261 gtaaagaaac aaacggaatc acattatatt ttaagcagga ctgaaagact ctatggtaat
    16321 aacgaacagc caatatattc ggctccccat ctatatcagg aaatatacga acccaagaaa
    16381 tagataaacg caaagcctgc aaaccatgtt ctgccgccaa agctatatcc tcttcgtaac
    16441 gataataaaa atcactagct ggatctggta agaacggact attttcttgc aaataaacat
    16501 cccacatatt tattcctttg ccatctaccc tagttgcacc ctctacttga taagcagcgg
    16561 tagcagctcc taataaaaac tccttcggta aggctttaac ctgtaaattt tccatgacta
    16621 atcctcattg caaaccaata tgttcttcaa tctttcgaat tcgttcatat tcatcaataa
    16681 aaaactttac ctgatcatac aatagcatcg ttgtcatcaa agtatcttga ccatgaatca
    16741 tgataaaact cacttcaaaa ttatctccat atgcctcctc cgctaataaa ttagtctgtt
    16801 ctcgatgggc agacactatt gagtcgtttg cagactcaac caattctctt gcctgttcaa
    16861 aatatccatc tctcgcaaac gccaaagcat ccatcaaatc tgaccttgca tctcctgcgt
    16921 aagcgacaat tgtaaaacca agcatattta tttcttcttt tgatttcatc tttcttcctc
    16981 ctcaatcttg aaccatcttt tacacatcat tattaaaatg acttcgctac gatacaaata
    17041 gaaagtcgac cctaaatatc ttaaaaatcc ttaaatttca taatatttag gatcaatctt
    17101 ctctgaatac cttggttcat tttctagact tatgatttat aagtggaaac cagcgtaatt
    17161 ttttgctact tcaattacac gataaacatc caaattagat tggaatagca gttcgtgccc
    17221 acggatataa ttcaacacat ttttccactc atcttgagct tgccttgttt ttccggttgc
    17281 ttgaagatat aaagccttcg ccatcttgac aacatattca cgatgataac tgagctgttt
    17341 ccattcatcc ttttgactat ttaataactt agaaatattt tcctcaataa ttggtaaaaa
    17401 attatcagct agattgtaag ctatataata atgattcgct aaaacatcac tttgacggct
    17461 gccaattgca ttaaaataat cacaagagga ataaatggat aatttttcta aatattcaac
    17521 aacagactgc caattttccc catacaaagc agaaaagtat tcttcaatca attcttcata
    17581 atttcttgtc ttcttccaga gcatttgccc catgacataa ttaggaaaat tatgagggaa
    17641 tccggcacgt aattcttgac acgaaatgta cccgttcaaa tgtaggttgg aaagataaga
    17701 tacatctctg taaatagttt gactaatttt catatagcct aaatcgccat aatgagcacg
    17761 ccctaaagga tagtcatata cgaaactatc tcctttaaat gctttttgcc actcaaaaag
    17821 ataagataaa ttttcctcaa gagaattcgg aagtataatt ttattacgca gataaggttt
    17881 aggcgtaggt atggaattgt caaaatctac atctgcataa ctcatttcaa atgttcttgt
    17941 aatcggtgca aacatcatgg taaagcgttc aggattatct aatttttctt tctgaggtgc
    18001 ccataacaac tcatgataaa gcagaaaaca aatctttgta tctaatccct cactcgttaa
    18061 agccctatcc aattgattga gaatacgaat atactgatcc gaaaccaatt cttgtctaca
    18121 gttttcgcat tcacaaatat tattacgagc atccgacaac catacatgta agtagttaac
    18181 atcaggtctt ttcttggcat aatccttgat aatttctacc atcttatcag ctacatctgg
    18241 atttgaaaaa tccaggctgg ttaaaatcgg agccgtatta aacaattctc gtttcccgtt
    18301 tatttcagcg acatagggtt tcttctcctc tgaaatacta agacctgatt cccagccaaa
    18361 ttttgaagag taacctaaaa cttcacctgt ccatccatga ccaacacgat gatgaataag
    18421 acctcttttt tgcaattctt tatccaacct atcactcaat tcttgtacta attcatttga
    18481 aaattgttct ttatttagat atggattaaa ttcatgttca taccaacgtt tcaaaaaaga
    18541 gtagggattt tcaaactgga tgaaaaaact gttcatccca atcttaggta gccaatcaat
    18601 gaaatctagt atattttcaa atgaatccgc tccctctata catactcccc tatgatagta
    18661 actggctgtt tcatctatag atagctgttt atctaaaaaa tcttcaaatc gtaactctgg
    18721 aacaaagtca tgtccgcgcc ctggtctagt atacacaacc ccaaattcat gaaacattcg
    18781 gtaaattcca ataagtaaac ctacaattgt attagactca attctcccct tacccttgtc
    18841 taatgagata agaacatggt ctcttctatc ctctttattg actaatccta caaaaatatc
    18901 cgcttccttc tcctcgacaa gttctatgtc agtcttaaag acccgattta tatagtaact
    18961 taattcctct aaggcaaagc tagaataagt atttttctgc ttatcaaata ctctgataac
    19021 catcttattt ccctccaaca gtagcttttt ctttttcaag attgcgttta tctgcaattt
    19081 tgaagaatgg ataataaatt gctacagaaa ccaaaatcaa aacaacttgt aatagagctc
    19141 ctcgccaact agctcctgtc gcaaggaagc ctcctatgat cggtggcatt gtccacggaa
    19201 ggattacacc tgttgtatag ggtactaatc ctacagccat tgatacatag gtaattaagg
    19261 cattgattgt aggagtagca ataaacggaa tcagcataat cggatttaaa actgttggaa
    19321 acgtaaatag aatagctgta ttgatattaa aaatagacgg tataatagct agcttaccta
    19381 atgttttatt cgcacgactc ttactaaata ggaagagaca aatcgcaaga ccaatagtcg
    19441 ctccaccgcc accaataaat acaaataaat ctttaaacgg taatgtaata atgtgttgga
    19501 gtgtttgtcc tgcagccaca gcttcttggt tttctgtagt aaattgtaac caaactgggt
    19561 ctacaaaagc atttaaaact tgtcccccat taactccaca gaaccaaaag aatgagttta
    19621 caataacaca tagaatcata cctggaagcg ttcctgcaat taacttaagc ggtgttccaa
    19681 caattgcacc taggagtccg ttgagacctc ctgcaactcc tgccgcttca agacctttta
    19741 agaccagagc ccacaaaaca aaagtagtaa agccaggtaa aagagctgaa aatgatttac
    19801 ttaccacatc tgggacacca cttggcattt ttatcgtaat tccgcgctgg ataaacatac
    19861 gataaatctc tgctgtaacc aatccaatag taatcgccat aaacaaagaa gatgcattca
    19921 gactagaaaa tggtattgcg ccgccaaata actgcttgac ctgctcccca tttttatcat
    19981 aaaccatact cgaaaaacga ggtgccatca atacaaaact ggataaggct atgatccctg
    20041 ccgacggacc atctgtacca tatccttccg acaacctgta ggcaataccg aaacaagcga
    20101 ccaaggagat aatcgctact gttgactgat tcatagttgt caagatactt agcaatccaa
    20161 cactattcag ccaatttgta aaagcctctt gaggccaact gattagaata agaaataaag
    20221 agccgactaa aatcaaaggc attgccatca taaatccttc acgaatagct ttcaaatgcc
    20281 gttggttgcc aactttttca ccaaacggag cgacttttgt ttctaaaaac gctaaaatat
    20341 tgttcatcac cggaactcct ttttttattt tttataaatt aaatatacca ctaacagaaa
    20401 gcgttgtcaa tatatttttt gttattttta caatattttt ttctttgtat agaataataa
    20461 ttttaattga ttttttctta tgtttaatat aaaataaacc aaaggaggaa acaaatgatt
    20521 acaaaacaat cagccttttt acaaaataga gccactatac tggagtttct atatcgaaat
    20581 ccagcaacat cccgtacaga tattgttaat gaaacaggac ttactccagc aacaacgact
    20641 aacatcataa aagagctaag cgaacagtcc ctcatatacg aaactggtga tgaatttagc
    20701 gagttttccg gatctggaag acgtagaaaa actatttcta tcacagataa tattccgtat
    20761 gttgttggag gtattgaaat aaacgtccta ggtatctttc tcagtctatg tgacttacaa
    20821 gggaaaactc ttttcgagac agaaattttg aatgaagatt atcctatttc agaaatcaat
    20881 tccaccatta ccaatatgat aaaaacagct atagagtacg tccctttgga aacaaaatta
    20941 cttggatttg gcttatcaat acctggacat tataacaaag actccggaag tatcattaca
    21001 aacaacccca tatgggaatc ttttaattta ttaaatgtaa ttaaaagatt caattttcct
    21061 tttattgtaa aaaataatat cgattgtatg gctataggac aatacctttt taatccacac
    21121 aatacccccg ataactttat tttcctgcac gctggattag gtatttacac ttcctttttc
    21181 acaaaagaaa aaataggagc ctctaaaaat ccttatatcg gagaaattgg acacaccatt
    21241 gtcgaattga atgggcaata ttgtgaatgc ggaaaaaaag gttgtttaca aacatatatt
    21301 tcggatgctt ggttaatcaa acacgcccaa ttattattta aaaattccca actaactgta
    21361 ctaaaaagcc ttgtaaagac tgaaaaagac attcatttag acaccctttt aacggcttat
    21421 aatttaggcg actccgcttt acgtcaacaa attgataaag gagtcaattt attagccact
    21481 tctattgcaa atctcctcct catcaatcct gctgataaaa tctatatcaa cagtcaattg
    21541 cttaattatc aacctttcac tcatgaagtc agggataaaa tccaagacca gctccacttc
    21601 gttcccttta ctcgtaatat agaaattgaa attttacctt acaacaaaca tcgtggaagt
    21661 ataggagctt gtgcattagc tatcgtcgct tttttcatag aacatagcaa tgtattacaa
    21721 gatattattt caccttaata tattagaaat ctatagacct gtttaaatca actataacct
    21781 gtagtagata tctcgtattt agacaatatg aaaacaagac gacttccata taggaaaccg
    21841 ccttctctct atgttgagtg atttatatta aaataacttt tcttctagct gcattttatt
    21901 attataaaaa cattcatcat aaccctgaac ttaaataacg atttttattc aagatacata
    21961 ctcctagaat aaactttata tgaaattctc atttttgttt ttacaattct ccttagttaa
    22021 atcttgttta atatatgttt tacatatagt atttagcgcc acatagtact gaactctctc
    22081 caaaaacggt tattcctctt tgaatagggc gttatcacaa gaaaagcatc tccacgtttc
    22141 aacttcatat ggctcaaaaa caatcaattg atgctaaaac ctgtacctag atgtttcggt
    22201 tcataaaacc atgaaactgt aaaagtggat gaaattgata gcgatagtca aatcaagagg
    22261 catcataact ctaaaaagtc acaatatata agttcatcct cggaaaaata tcattctaat
    22321 tgttgaaatg cctacatgaa aagaaacgtc aaatactcat gaaacaacga atacaggtat
    22381 caaaactatg acaaaacaag tccctaaatt tactaaagac actgctcaac tttacacctg
    22441 taaatggttg ttgtataata aagttacaaa gatgtacgac cacactgttg taaatcatag
    22501 tgttcgcgaa tatattactg atagcatttc tacaaataca attgaagaga ctggatagac
    22561 tttaaacgaa atatgtcagt gttttggcat tcctagcctt catatcattt aaagaattct
    22621 atagacaaaa tttttcccaa tacagacact cgtaacaact gcttcatttt tctaccaaca
    22681 tatttaggaa caggataaga tacaagagga ttaatccata gatcagttct ataccaatct
    22741 aagacaaata agctaaaaaa acgattgata ataagcaaat agattccaaa ttttctctat
    22801 ctgctcattt taataaacaa tactagtgta actatccttc cagtcagaag cttgtcaaat
    22861 cacaccgaaa attcttctaa aatttatctc gttaggcaat caagcaaaaa ctcgacgata
    22921 gtacaaacat tatcatacag aattgacttc ctaaattata tactttagta aggttttcgt
    22981 ataagaaaaa agattcattt tacatttcta aacattcttt tctaagatga aaaacagaat
    23041 ttttcgattg tgatttaaag caacaagaag attttcagta tcatcctata gatacgagct
    23101 aattaagaaa aactacattt tcgaatataa actacaataa tataaactaa attttatagg
    23161 aggaagacaa tggattggta cgattatatg atacaggcat ccaaacaatc acaattcaac
    23221 gcaagccatt ggtttcgcta tttgcgaaaa gttatttttg aagactattc ttatttaaca
    23281 aaccaagatg tagaaaagtt gctagactcc aaagaactaa cccgttttca aaaaattagc
    23341 ttgaagtatg cctttcaaga gcatactcca actcataaat atgtgatttc attaaataaa
    23401 cctgctaagt taaccaatgt tcaaaaattg atggagaaat acaaacatgg ataaaatgaa
    23461 accggtcttc caagccctaa ataaggaatt aattcaggaa aatctgactt taacaattat
    23521 ctgtgtcgat ggttatgtct tagaatatca tggtttacat gccacacaag atgttgatgc
    23581 tttttatgac caaaatcaga aaatcaatga aattattgct cgtgtaggaa aacagtttaa
    23641 tcttaacatc cacgaagagt tatggctcaa caatcatgtt gcaaagcaaa tatgaacaaa
    23701 caacctccct taagtttatg cgaatccttg tactcatttg agaatctgac cgttttagta
    23761 gtccctattg agtatgtgtt aggaatgaag atgatgagta tcagagagca ggatttgcaa
    23821 gatattggtg caattattaa atacaaaaac tttcattcac cattcgatac ctttaaatat
    23881 ttaaaagaca tgggatttga tactattgac ctctctgttc tattagaaag ttttagttat
    23941 gcttatggta tggattggtt agaaaaattt tttaaagaaa atcaagataa acttcgcgaa
    24001 ttttattaac agtatcaaac aagatgattg tcaattagcc agtcgtcttg ttttttatga
    24061 tgaaatgaaa taaaatctga acaaatcgct tagagaattc cagtcaattt ctagcgctgt
    24121 ttgagacgtt tcagtggact atagtaaaat gaaataagaa taggacaaat cgatcaggac
    24181 agtcaaatcg atttctaaga atgttttaga aataaaggtg tactattcta gtttcaatct
    24241 attatatttc agattcggtc cactattcct tcccaaaaac attgcatatt gcgccgaagg
    24301 aattgctcat actatcccaa gcacaaaacc ctcagtcgtt tgaccgaggg ttccttttta
    24361 ttattcaaga acttgattag ctcaatgcat ccaaggcgtc atccattgaa agaacttcgt
    24421 ggaagacacg ttgtgtcaat tcagtttttt gttctggagt gaggtattta gtgtttacac
    24481 agtatccaga gatacgtacg ataacgtctt cgcctgacat gattttttcg taaacatcgt
    24541 tcaagtccat aacgttcaag ttaacgtgtt gtccaccgtt ttcgaagtaa ccatcaagga
    24601 ttgttaccaa gttatcaact tgttcatcac gagtcttacc aagagcgcga ggtgatactt
    24661 gtgtagtcaa tgagataccg tcagctgcat aactaaagtc aaggctagaa agtgagttca
    24721 agttttgcaa ccaaccacct ttagctttgt tagatgggtt agcacctggt gagaagaatt
    24781 caagtttaga caagttcaca gaaccatctt cgttgaggta tacacctttg tgaactggtg
    24841 agttaccagt ttgtttagag taagcaacgt tagatgtgat tgtcaaaagt gatactgtag
    24901 cttctgcgtc tttgtatagt ttgtggctac gtagacgagt tgtgtaagct tcgatcaacc
    24961 attctgccaa ttcgtttgaa cgtgggtcat cttcacccca gcgtgggtag tcaccgattg
    25021 tttcgtaatc gtagatgtag ccatcttcgt cacggattgg tttaactgta gcgtatttga
    25081 tagctgacaa tgtatcaaca gtgttagcaa atccacagat accgaatccc atgttggcac
    25141 gttgtttagt tggcaagaag gccatttgaa cagcttcgta gttgtaccta tcagtcatgt
    25201 agtggatgat gttcaaggca tctacgtaag tgtcagtcaa ccagtcaaga gatttttcaa
    25261 agttcgcttt aactgattcg aattcaagaa cttcgtcacg gattggttcg atatcaaata
    25321 ctttgtagtc tttgtgaaca tcgtcgtaac caccattcaa accagtaaga agggctttaa
    25381 gaacgtttac acgagcaccg aagtactgga tgttgtggcg ttgttcttca ttttctggat
    25441 caagtggaga cacacagcat gagatacagc tcatttcacc atatccgtct ttagccattg
    25501 ttgttacacc ttcgtattgg atagaagagt gtttgtggct catgtgcata cagtagcgac
    25561 ggaagttgta tggcaatttg tcagtccaaa gaactgtcaa gtttggttct ggtgagttac
    25621 cgatgttgtc aagagtgttc aagaaacggt agtccatctt agtaacacgg tgacgaccgt
    25681 cgttacccat accagccata gaagttgtga taaaggttgg gtcacctgag tacaattggt
    25741 cataagcttt ggtacgagca aatttaactg tacgaagttt cataacgaaa tcatcaacga
    25801 attcttggat ttctgattca gtaaatgtac cacgagcaag gtcacgttct gcaaagatgt
    25861 ccaatacgat tggtacacga cctagagatg tagcagcacc gttaatcaca cggcagacag
    25921 ccatgaaagc aatgttaacc cattggattg cttctttcac gttcatcgct ggtttgcgaa
    25981 catcaacccc gtaaaggtca cccaggcgaa caacttgttg caatgcttgg tattgaaggt
    26041 ttacttcttc acgaagacgg attgtttctt catcgatttc tttgattgca ttccagtcat
    26101 ttactttttc ttgcatcaag tagtctgcac cgtaaagagc aagacgtgcg taaacaccga
    26161 tgatacgtcc gcgtgagtat gcatctggaa gaccagttac agtgtgtgcg tgacgagcgc
    26221 gacgaatatt tgaagtgtag gcacggaaaa taccgtcgtt aactgttgtt acatatttag
    26281 tgaagatttc gtgaacagct gggtctggtt cgtatccatt ttctttcaaa gtagtttcag
    26341 ccatacggat accacctttt ggcatgaagt tcaatttgaa gagttcatcg ttttggatac
    26401 cgaagataac ttcattttct ttgtcgataa atccagcagg gatatcagcg atagatgttg
    26461 gacgagtgtc cattgggaaa cgagtttctt cgtagtgtgc tttagtttct tctacaattt
    26521 tcttgatgtg aagtgaacgc tctgttggtc ctgcaaggaa gctttcgtct ccatcataag
    26581 gtgtgtagtt agcttgtaca aatcgtgata cacttgcttt ttctttccaa tctacgcctt
    26641 tgaagccttc ccaagctttg tcaaaaatat cttgtgcttc aacaactgtc ttaacaacca
    26701 tattaatgtc ctcttttttc tagtaacagt catctgttac attcataaga caagtatacc
    26761 atatagtaac cgatttcaac aagtgaaaat tccctatttt tacactttct tttctaaaac
    26821 agtctatatt ttatttcaaa ctgtattata tttttgaaaa aataaagtcc ttttttcttt
    26881 ttttcagaaa aaagggtata ataaaagaaa ataagcagta acactcaatg gaaatcgaaa
    26941 agcaaactag gaagctagcc gcagattgct caaaacactg ttttgaggtt gcagatagag
    27001 ctgacgtggt ttgaagagat tttcgaagag tataaaaagg tgctaggcat gttgattttt
    27061 cctttgttaa atgatttgtc aagaaaaatc atccatattg acatggatgc cttttttgct
    27121 gcagtggaaa tcagggataa tcctaaactc agaggaaaac ctgtcattat tggaagcgac
    27181 cctcggcaaa caggtggacg gggagtcgtt tctacctgta gttatgaggc aagagctttt
    27241 ggtgtccatt ctgccatgag ttccaaggaa gcttatgaac gttgtcccca ggctgtcttt
    27301 atctcaggga attatgagaa atacaagtct gtgggactcc agattcgagc tatttttaag
    27361 cgctatacag atttgattga acccatgagc attgacgaag cctatttgga tgtgacagaa
    27421 aataaactcg gtatcaagtc agcggtcaaa attgctcgcc tcattcaaaa agatatctgg
    27481 caagaactcc atctaactgc ttctgccggt atttcctata acaagttctt agctaaaatg
    27541 gcgagtgatt atcaaaaacc tcatggtttg acagtgattc tacctgaaca ggctgaggat
    27601 tttctcaaac aaatggatat ttccaaattt catggagtag gaaaaaagac agtagaacgt
    27661 cttcatcaaa tgggcgtttt tactggtgct gatttacttg aagttcctga ggtgacccta
    27721 atagaccgtt ttggtagact aggctatgat ctgtatcgaa aggctcgtgg cattcacaac
    27781 tctccagtca aatccaatcg catccgtaaa tcaatcggca aggagaaaac ctacgggaag
    27841 attctctgtg ctgaggaaga tatcaaaaaa gagctgactc ttctatcaga aaaagtcgct
    27901 ctcaatctac atcaacaaga aaaagctgga aaaattgtca ttttgaaaat ccgctacgag
    27961 gacttttcaa ctcttaccaa acgaaaaagt attgctcaaa aaacacaaga tgctagtcag
    28021 ataagccaaa tagccctgca actctatgaa gaattaagtg agaaagaaag aggtgtccgc
    28081 ctattgggga ttaccatgac tggattttaa agctcaatga aaatcaaaga gcaaactagg
    28141 aggctagccg caggctgctc aaaacactgt tttgaggttg cagataaagc tgacgcggtt
    28201 tgaagagatt ttctaagagt ataaaacctt gaagagttgc cccttcaagg tttttcttat
    28261 acaaataaac ggacaaaact gtaaagtagc aaaacactac caagcacgat acggtattta
    28321 ccaaaaaggg tgaagtcgtg ttttttcaca tagctggtca agaagcgaat agccaccatg
    28381 ctgaccgcaa aagctactcc catcgcgacc aagagcaaaa acaattgccc aaagctcaag
    28441 agttctccgg ctttcacaaa tttgaaaatc tttaaggcac tagctccaaa cataacagga
    28501 atcccaagat agaaggtaaa ttctgtcaca actgaacgac tggttccatt taacaaacca
    28561 ccgacaatcg ttgcacctga acggctagtc cctggtaaaa gagcaagaac ttggaagagt
    28621 ccgatataga aagcggtcgt ataaggaagc ttgtccaact ctgttacact tggctcgata
    28681 gcacgcgctt tattgcgctt ttccaaatag atgaaggcaa ccccgtagat aatcaacatg
    28741 agagcaactg aaaccatgtt atggaagtgg gtatcaaacc aatcatcaaa tttaaagaca
    28801 ccaagtaaag gtaaagtagc aatcaagacc ttcaaccata gtctccaagt cttacgaact
    28861 tcctgtttgt ccttagtcgg tttaaaagga ttgagcttgt taaaataaat caccataact
    28921 gctaaaatag caccaagctg aatcacgaca ttaaacatgg acataaaggc ttcattttga
    28981 ttttggtatt ggatgaattc ctctgctaaa atcaagtgac ctgtactgga aatcggcaac
    29041 cattccgtaa ttccttcaac aatcccgaag aagatagatt ttaaaatttc aataagatac
    29101 atagattact ccctatatta taattagcgc agttagctac tgccaaagcc caagtggtat
    29161 acttggaata agccactgtg gattagttca tttcctccaa tcgcttgacg atttccgaaa
    29221 gg
//
LOCUS       DAVHLA010000027        27576 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVHLA010000027 DAVHLA010000000
VERSION     DAVHLA010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27576)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27576)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27576
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.027"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(326..517)
                     /locus_tag="VVO77_001319"
     CDS             complement(326..517)
                     /locus_tag="VVO77_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000834563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693329.1"
                     /translation="MKSFKDFRESLTAEDMQAISAKANEATKQIDHTDGLQLGKVSGL
                     TSVITTIELLEKYHEWLHS"
     gene            636..779
                     /locus_tag="VVO77_001320"
     CDS             636..779
                     /locus_tag="VVO77_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693330.1"
                     /translation="MEDKIIELADYFISESTTYREAKIACEKLLKQVSHEIELRAMES
                     KTV"
     gene            846..1643
                     /locus_tag="VVO77_001321"
     CDS             846..1643
                     /locus_tag="VVO77_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001056933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="HEU5693331.1"
                     /translation="MNMNLNTNEILTTTEYDIFRKISNRKITENPKLEEELLSEGQRQ
                     PILVNEKMEVIDGQHRLYYLRKHRKPVRYIIDPTANFKTVISMNTSAVNWALQDYVYS
                     FALEGDPEFVKLAKFLDENELLSDKMVIVAGSGRRDGTAAHVVKKLKKGDYVFSNEKQ
                     LREFCKFYERVLNETKLPNKPFLQSVLWTLYTTSVFDENRMLTQLKKSDLTSEDIEGF
                     AKKKLLLTFLELYNGRWSDDHPSLIQYFINRKGSLTIPSLPKQDEDN"
     gene            1661..1798
                     /locus_tag="VVO77_001322"
     CDS             1661..1798
                     /locus_tag="VVO77_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693332.1"
                     /translation="MKVTVYVYGRKLEPDEPIIIPENHRFYDIWNGIVNEMLDNEEDV
                     A"
     gene            1798..2019
                     /locus_tag="VVO77_001323"
     CDS             1798..2019
                     /locus_tag="VVO77_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693333.1"
                     /translation="MKLLTKLKLRLEGVLKSVNLDWREVAVELMNDLFEERKRRFAFE
                     QENYDLKQELAAYKYKENFDIKARLQGEM"
     gene            2020..2274
                     /locus_tag="VVO77_001324"
     CDS             2020..2274
                     /locus_tag="VVO77_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693334.1"
                     /translation="MYIISIYVKNTETGNEDFSLIGRDFLPTGHQDYIARVFGTKEEA
                     IDYLKSISYIASGVHGNDWVYQNEKLPEIESRCRIWKVGE"
     gene            2287..2547
                     /locus_tag="VVO77_001325"
     CDS             2287..2547
                     /locus_tag="VVO77_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693335.1"
                     /translation="MFKALKTIKKIKQLQKEMHAFSLAFLALQDMGLMPETERSKAKA
                     QTMHDVSRVLKDVLDGKSVDEAIKRLNSEVKAEEVGQKDDQN"
     gene            2817..3635
                     /gene="bet"
                     /locus_tag="VVO77_001326"
     CDS             2817..3635
                     /gene="bet"
                     /locus_tag="VVO77_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000184013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage recombination protein Bet"
                     /protein_id="HEU5693336.1"
                     /translation="MTNNQIVEAKGDFLTNPQLLNSGIIRKYLDPQGKASDEELAYFI
                     AQAKAQNLNPFTKEIYFIKYGTQPAQIVTAKSAFEKKADSHPQFDGKEAGVIYLMDGE
                     IKYSKGAFIPKGAEILGGWAKVYRKDRIYPTETEVSFEEYDNSKIRARVKELTQQGKD
                     VTYPVMNSYGKPIGENNWDTMPCVMIRKVALVSAYREAFPAELGASYEADEIQLDNTP
                     KDVTPQESREDVVARKMAQIDQFNKEQEANHADPEPAKTEEPIQGELLDGELEY"
     gene            3645..4709
                     /locus_tag="VVO77_001327"
     CDS             3645..4709
                     /locus_tag="VVO77_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001157031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1351 domain-containing protein"
                     /protein_id="HEU5693337.1"
                     /translation="MQELQVIDDKKINKIYEMITTDELTRESFEKDLIEATEKYKDYI
                     PTAGTLKDDKAKRAEFNKLIESKNRIRIDTKNLLSETANTWDSYAKSIIDPFATVVSE
                     FDKGIKEIEEHQRQLKIDTVKSYLANKSAEYMLDPRLFDEKALEYVKASDFMADGVTL
                     KKATMKSLDDMVTFEFQKQQEFEKAKSAISGLCAEYGMTDSPYIRQLKDLTLAEVFGQ
                     IKADYEFEKQKEELRQDLERAERSNQELLAAQQTKQQEQAPKSTETPNFDPETGKILD
                     GGQILQNEPNALRGAENDLKRYAQKMTLEVYFVDTAEKDRFKAGLSQLGFDFKKNYQV
                     RGYQRIDPLTQAELNEQCGW"
     gene            4877..5200
                     /locus_tag="VVO77_001328"
     CDS             4877..5200
                     /locus_tag="VVO77_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693338.1"
                     /translation="MDIRKISDSVAIYSDGKKLQVIHNLGDEFILDFKVGEDSVWNLN
                     GQVVEIIDMIEPVFKVFSFCSKSGEGMQRLKHAIVHFEKFEQYIRDNQEDLMIWWHNP
                     GGEYD"
     gene            5193..5528
                     /locus_tag="VVO77_001329"
     CDS             5193..5528
                     /locus_tag="VVO77_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000598346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein Cse60"
                     /protein_id="HEU5693339.1"
                     /translation="MIKTVFFSCDYPHHEVIDDQINSWLAENPGIKLIDIKFQSNVSA
                     VADSGVSAEYWHTSALIIYKVPSENNISSINSNGLGFIISCEKCGSLSIIKGKDVGQN
                     VCYECKGEK"
     gene            5623..6039
                     /gene="ssb"
                     /locus_tag="VVO77_001330"
     CDS             5623..6039
                     /gene="ssb"
                     /locus_tag="VVO77_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEU5693340.1"
                     /translation="MINNVTLVGRLVAPPDLRKTPNNVSSLQGTLAVNRNFKNENGER
                     EADFINFQAWRGTADIIAQYCSKGSLIGIIGRLQVRSYEKDGQRRYVTEVIAESVALL
                     ESRNSQHGQGNSFQNGNSSPFTDPNPFDLPNDGLPF"
     gene            6052..6450
                     /locus_tag="VVO77_001331"
     CDS             6052..6450
                     /locus_tag="VVO77_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000401829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693341.1"
                     /translation="MEIDKIIKKDVLEFMETISDNKIDASKINVTERIAIIIEKQKIE
                     VVTTLNYDMSISFDNKDTAPTLDDNGDLFEPVYKCKVKAIPKNDVFFTSLTRVKSNTK
                     TLQEVKKFFEFVNENRENLFEMAGFKGVLE"
     gene            6447..6878
                     /locus_tag="VVO77_001332"
     CDS             6447..6878
                     /locus_tag="VVO77_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HEU5693342.1"
                     /translation="MKLTLNIEPKPQSRPRFARRGSFTTTYEDKDMKTWRNHCQLLIA
                     NQYMGQPILEGALRTRLRFYIKPPQYISKVKKNQQALLDEIIPVGKKPDIDNYEKALY
                     DSMSGIVFQDDGQIALHDVGKFYSLNPRIEVEIEVMKSLSI"
     gene            6894..7076
                     /locus_tag="VVO77_001333"
     CDS             6894..7076
                     /locus_tag="VVO77_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000796349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693343.1"
                     /translation="MADYALYQGDVFVTLGTLAQISSETGITERMLKYYTYTSHQRRH
                     PNGRAVIKIEEEDNEN"
     gene            7101..7418
                     /locus_tag="VVO77_001334"
     CDS             7101..7418
                     /locus_tag="VVO77_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693344.1"
                     /translation="MMEELKQKVNEVYNWTVEDGKPQPPKQDLPQAVKDRADYFWEMA
                     EDGMTFMGAMECIFADEKPIDYDLGATKDWLPKSKEFDDWVGYSPSMAQVVIAVYLIY
                     RGN"
     gene            7420..8112
                     /locus_tag="VVO77_001335"
     CDS             7420..8112
                     /locus_tag="VVO77_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEU5693345.1"
                     /translation="MNKQELIKKLEERRTITGNFQGYVVWWKDVKEIFEQLDESEIGH
                     ADEAPRYVKNILARLRELPLHDREVWLKAIMSEFEQDFSRAKWREGYEQGKIEGMVER
                     EKVIVPQCVAEYIEFKKKNNFHVYGAMRVIEDHYDKKVPDWFYENNIEKFCLAWLDGY
                     EVEKEKRYFVKIKGNIKENMLVYGELLKRYFFTKSFSLDDVIYSHTRKELEDAKFGWV
                     FDCPGIEIEEVE"
     gene            8270..8530
                     /locus_tag="VVO77_001336"
     CDS             8270..8530
                     /locus_tag="VVO77_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1372 family protein"
                     /protein_id="HEU5693346.1"
                     /translation="MKRFIAIWILLSAGLNIWQMDRIRDLEEKKPMVIYKADNAGVEI
                     FGKVVEKGRHGKLYTLTIRDYGVFVVTKDVYDKVKVGDEVLL"
     gene            8527..8949
                     /locus_tag="VVO77_001337"
     CDS             8527..8949
                     /locus_tag="VVO77_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693347.1"
                     /translation="MTETIKLPDYYEPDWKNARYGSLEELKELLLFKRIVKWDKDFLL
                     LEDGTKVTIEMSESDCCASAGGEFQDVSLDAVITNIEIGEPEEIPDHWGTGYKNKVTI
                     FHNQNPVAIANCEAEHNGYYYSVCSLVIGDIHFPVVNA"
     gene            8961..9398
                     /locus_tag="VVO77_001338"
     CDS             8961..9398
                     /locus_tag="VVO77_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000612395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693348.1"
                     /translation="MIPKFRVWVKIGKRMVFSDDILAIDYENKEIVTQQVYFENGLPD
                     DRDIYCYDFDEIELMQSTGLKDKNGKEIFEGDIVRTTRFLGRADEIGGFYEYDKEFIG
                     IVKQLEGSWVIDTGSDAVCLWTEIEENEIIGNIYENKEFGGRK"
     gene            9395..9766
                     /locus_tag="VVO77_001339"
     CDS             9395..9766
                     /locus_tag="VVO77_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693349.1"
                     /translation="MRPCKYPYSGRRKKQETPSPIFSARPIFDEVPIVEEVKVEFGVE
                     ASMGRIYPETLIHLDISGYGNRVHSVHRFPGILLSVGESIQLKMLFYKRLRNFTTDRF
                     LTFRESDWKFFIRDLVNEFKH"
     gene            9839..10243
                     /locus_tag="VVO77_001340"
     CDS             9839..10243
                     /locus_tag="VVO77_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEU5693350.1"
                     /translation="MNKAKELLKELQDLDMDIQSRIDEINELEAGLLSSPKWSEVKVQ
                     GGQTRKVDDVYTQLVVMKEAIEQDTKEVINRKLELGRMINRLKNPKYRAVLRMTYINK
                     GTADSVCYDLNMSRTTYYRLKNEAVLALEEVI"
     gene            10324..10406
                     /locus_tag="VVO77_001341"
     tRNA            10324..10406
                     /locus_tag="VVO77_001341"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10355..10357,aa:Tyr,seq:gta)
     gene            10712..11152
                     /locus_tag="VVO77_001342"
     CDS             10712..11152
                     /locus_tag="VVO77_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEU5693351.1"
                     /translation="MSRLRIKQKRFADEYIISGNATEAYKKAGYRVSSDRVAGVEGHK
                     LLKNPKIKSYIDERLKQLDSEKIADQQEVLSYLTSVMRGETQEQTLISIGELGQTITD
                     IDVGAKDRIKAAELLGKRHRLWTDKVEAAVSGTVVFANESDIPD"
     gene            11130..12428
                     /locus_tag="VVO77_001343"
     CDS             11130..12428
                     /locus_tag="VVO77_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEU5693352.1"
                     /translation="MSQTYQIKQSDIVIDLPKTVGAGYGQFWRSRNLYRVVKGSRGSK
                     KSKTTALNYVIRLLKYPWANLLVIRRYSNTNKQSTYTDFKWACNVLGVTHLFKFNESL
                     PEITVKATGQKILFRGLDDELKITSITVDVGSLCWAWFEEAYQIETEDKFSTVVESIR
                     GSLDVPDFFKQITVTFNPWNERHWLKRVFFDEETSRADTFATTTTYKCNEWLDEVDIK
                     RYEDLYHTNPRRARIVCDGEWGVAEGLIYENVTVKDFDKDELLRDSANKLCIGLDFGF
                     THDPTALCCSLINDTTKEIYVFDEAYKVGLITKEVAKMIKDKGYHRSQIIADSAESRL
                     IEELRSEHGISRIKESRKGKDSIMAGVSKLQGYTIYVHPDCKNIMDEFYSYCYQRDKE
                     GNWLNKPEDKNNHLMDALRYSLQCIEGGKATVRRRSDYGL"
     gene            12440..13909
                     /locus_tag="VVO77_001344"
     CDS             12440..13909
                     /locus_tag="VVO77_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEU5693353.1"
                     /translation="MYQYLTYPRDGYDEGSLKKDLIYKLITIHSTEGSHLKKLKSYYL
                     GEHAILEHTRRNVNAPNYKTVANHAKDIADTATGYFMGNPIKYNNTADGDIDELLTAF
                     DGAEIDQVDAQNALNMAIYGRAYEYIYAKEGMAELDSTSIDPENTFMVYDDSIERKPL
                     FAVYYYEVKDDTKDTTKHQAEVFTENLHYHMVLRSTDSGTIQSEEATPHNLGQIPIIE
                     YRNNHFAIGDYEQQISLIDAYNSLMGNRVNDKEQAVESILVLYGTQLADTPEDAKVAM
                     KILSEEGLLELPGDSARAEFLKNTLDESATEILRTALKEDIYTFSHVPNLTDENFAGN
                     TSGVAMEFKLMGLEMITKTKEANYKRGLRQRIAIFAHYLGMKQIALESHSIVPQFSRG
                     LPKNLLEISQIVNNLEGKVTNRQLISLLPFVEDPDAELEALEEEKKKNMEDMPMFNKD
                     NTKPEDEVEDEESGVLGEEESQSDLPADGQGRKAGRSVR"
     gene            13818..15455
                     /locus_tag="VVO77_001345"
     CDS             13818..15455
                     /locus_tag="VVO77_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEU5693354.1"
                     /translation="MKNQEYWAKRKANLIYQQMDKAEKQADQFDKVYQEAKTYLDKEV
                     NKIFDKFQRDYGLSQVEARQVLKNMKDKKNLNELRKVLEARPNDPNIQRLLADLDSPA
                     YSFRMKRLERLSDDLDRMRESIYHSEKTGSDAFYSDLMKDSYYKATFDLQQQTGLAYG
                     FSGLPESEIKHLQSFSWVGDGSTYSTNIWKNTGKLTSSIKDELLISLMTGRDTRETAQ
                     AIAERFNVGQNDARRLVRTESAFFHNQMELLSYEEADIEKYIFAAVLDKRTSRICQEH
                     DNQVYDRDKAVPGVNCPPMHPWCRSTTVGYDEDADYSKLKRRARNPETGKTELVPADM
                     TYKEWYSKYVAKDGEKVYNQDTREAKAKFYSEQLLSKISGVEPKITSDMQRIAGENKL
                     AGLEFRKKTVESLSRKIIADSLVENISLSKAVSKINDALRYTTIFDSDTFTEEYLKMK
                     QKLIAEGYKIVKVKNTWPVDGPYKGVNTVVEKDGINFEMQYHTQESFDLKNGSLHELY
                     EKYRDTNTSDLERMKLFKEMLDLSNGLEIPKNIERVK"
     gene            15457..15666
                     /locus_tag="VVO77_001346"
     CDS             15457..15666
                     /locus_tag="VVO77_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693355.1"
                     /translation="MKDIKYYRTTTNNAQVLRLIDGVMQVFDIEKKWVNSMDWFNKIF
                     FNDFTDFEEISENDAFTYIDRMVAA"
     gene            15663..16076
                     /locus_tag="VVO77_001347"
     CDS             15663..16076
                     /locus_tag="VVO77_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEU5693356.1"
                     /translation="MIDIALAIAKKAHAGQVDKAGVDYIQHPLYVASQVNTEQEKAVA
                     LLHDVIEDSDITAADLFASGLSNEVVTAVQILTKKKGQSYQEYLGKVKSNNLARVVKL
                     ADLKHNSDLSRLKSVTNTDYERVKKYKNAIYYLST"
     gene            16119..16406
                     /locus_tag="VVO77_001348"
     CDS             16119..16406
                     /locus_tag="VVO77_001348"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693357.1"
                     /translation="MNKYKKLIELIENNGLEIQSKKCYDPQSAWHGEELWIVDKKKQN
                     KIFDLSGNGYCFHDAKVEEAIEEVEKYLLLKKMDTFDDFKKWVEKNAKPKK"
     gene            16670..17194
                     /locus_tag="VVO77_001349"
     CDS             16670..17194
                     /locus_tag="VVO77_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEU5693358.1"
                     /translation="MSEEINATVSTESTETVDTQENVDTVQEEKHERTFTRAEIGKML
                     SAERSKWEAEQEAKENEAKKLAKMNADEKQKYQLDQREQELADREKAIARKELTAEAK
                     AMLSERDLPVELVNVVDLTSAETVSESITSIQKAWEESVQKGVSERMKGSAPIKNAQT
                     VQQEVTEKWRKDFL"
     gene            17217..18242
                     /locus_tag="VVO77_001350"
     CDS             17217..18242
                     /locus_tag="VVO77_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HEU5693359.1"
                     /translation="MAFEELNTAESRKKHLGIIEDVLAVNSYSTPLVTSSDAVTLQGR
                     SFTVATGNTTELKDYKRNKDNEFDHVEVEEKVYTLDEEKYWGRFVDQLDERDSNGQVN
                     INYVIARQAAEVVAPYLDELRFGAALGNVSDNVAMGKTAGANNAYNAVLDVSEKLDEL
                     GITKERLLFVTPSFYKAIKSEIVRLPHGDADKKVLGKGYVGELDDYTVYKVPSKFLKG
                     VNALATAPGVVTSPVQVDNTKYNDNIPGRFGELVEQLLYTGAFVLEHFKKYIITIADS
                     KPAAKPSTQGKVVNRAKAWKTGTTYKEGDTVTHADKVYVAVKDISNSSTAPDTDTTNW
                     KEKTGKK"
     gene            18252..18440
                     /locus_tag="VVO77_001351"
     CDS             18252..18440
                     /locus_tag="VVO77_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693360.1"
                     /translation="MKFKIKQDFYDWESNVKRLAGEELEITEERYAELADNIASNGVA
                     ISDVLEEIFPKPEFLEED"
     gene            18442..18753
                     /locus_tag="VVO77_001352"
     CDS             18442..18753
                     /locus_tag="VVO77_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HEU5693361.1"
                     /translation="MSIELLKKLTGEEDTQLLMLLQTRATNLILSETNRTSLTPALSL
                     LIPEVAIELHNRSGAEGEHSRTEGGIAVVYGENGLSTDLLQRIRMHRLARVAGHVFEA
                     E"
     gene            18734..19072
                     /locus_tag="VVO77_001353"
     CDS             18734..19072
                     /locus_tag="VVO77_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693362.1"
                     /translation="MFLKQSRLKPYPMRRFEKTVTEEGVAKEGYAKEAETVRLELWPA
                     SSKLQSELYGERVNDILNANANKSATIKVKDGVCIDSQTEVTHRVISKKVYTHHQVLE
                     LERVRATRGR"
     gene            19047..19562
                     /locus_tag="VVO77_001354"
     CDS             19047..19562
                     /locus_tag="VVO77_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEU5693363.1"
                     /translation="MSGLLGADRLIAKCRRLASKKTGEDIVLRAVHNATIKVVQADAR
                     RLAPARDGELITSIKTRAKMDGDRAIGEVYTNLKYAPYVEFGTGPIGQANHSGISPEV
                     SVTYKSNPWYVHEDQINVGPYHFQKIGEFYKMYGQPAQPYLYPALRDNQERVSKNISN
                     YVRRKIREQIK"
     gene            19559..19927
                     /locus_tag="VVO77_001355"
     CDS             19559..19927
                     /locus_tag="VVO77_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693364.1"
                     /translation="MINIKPVIYKELQKVADNVTDTYPSDWETFPVVIFLEEQNKPGD
                     WFDDQEQKSSIRYKVDIFDDTSTSELAVKINQIFESLGLRRTDCQDVPDPSHLRHKVM
                     RFEGIVDLHSELVFQFRMEN"
     gene            19930..20343
                     /locus_tag="VVO77_001356"
     CDS             19930..20343
                     /locus_tag="VVO77_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEU5693365.1"
                     /translation="MLANGITLSYGETKDSYTKLVGLKEVPEFGIELEKVENTTLEDT
                     VKKYEFGIGDIGELEYKFSYNNSSATAPYRVLRKAADDKKKLYFEQAYPDGTKVIFEG
                     QVSVKLGGGGVNAVIDFTLKIALQSNLTFTDGIGG"
     gene            20348..20728
                     /locus_tag="VVO77_001357"
     CDS             20348..20728
                     /locus_tag="VVO77_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001185634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693366.1"
                     /translation="MALKYTTWKVTDEKELKLRLTSHQAATVEEKIGMNLLKIFMPEA
                     GEEFTLPPLKVMLLLVHGALQQYEHGYSLEDVYDLYDEYVDNGGDQTTFMTEVLMPLF
                     EVSGFTPRGSKDKKTSKKKMTVDK"
     gene            20767..21117
                     /locus_tag="VVO77_001358"
     CDS             20767..21117
                     /locus_tag="VVO77_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693367.1"
                     /translation="MFLDIGGKPLDFWDLTVLEIREMIESYNRVKIQERKEKIIDSYR
                     LSQMISNHVSLLLSKDAKAFEFWEYAPELFVEEQQAVEQERQKQALLLHKERMREFAE
                     RHNRKRKEEVNGNS"
     gene            21104..24757
                     /locus_tag="VVO77_001359"
     CDS             21104..24757
                     /locus_tag="VVO77_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693368.1"
                     /translation="MATLDELKVMIDAEIAPFRKKMKEVENQVKGTSDQVKNATAKVR
                     EQSSSIGSAFGKLAKFAGFAILGKKLLDVGMYSTQTALEVSASMNQIKRQMGESSQSF
                     LKWVNDNANAMNMGVGEATNYGAVYSNLFSGFIKDTNKLSAYTAKMLQTSAVVAEGSG
                     RTITDVMERIRSGLLGNTEAIEDLGINVNVAMIESTEAFKKFANGQSWQQLDYQTQQQ
                     IRLMAILEQATAKYGDTLSNSVNGRISLFKSLMKDAALNLGNSMLPIINAIMPVLNSF
                     AMVLKNVTAKLAEFIALMFNKKATVKDGVGGAVGDMGNAMKDAAGGAGDLADAVDDAG
                     DSAGGLADNLGDSAKNAKKAAKELLGLLGFDEINILQKPKDDDAGGSGGGGKGGKGKG
                     GGGGPFKDILPEVELTDMDNKFKSIFDGLGDKLKGLFDLFKKGFDAAFRPEGIERIKT
                     ALDQIAKTMGEIATDPRVVNAFNRMAEKIAYALGQVTGSITTIGLGIGVFLAESIANG
                     LGRQKERITRALVALFDNIGNISEAVGNIAQDFSSTFYDVITSTGAVRIGSAIVSTLL
                     SLTSTIVEVGSKLAGSLFKGFEKVVVTSAPKISSVFQSLLDTVAPVFESIERSVNKFG
                     DGLSRVYDEHVAPAINSIANAFNGLIDIIQILWENSWQPFAEFLSGVFGVSIEGISDL
                     LGGGLLATLGLLADAIKLVADGFTVFSDWCKENKEPILALITTWQTINFLSWAEQAGG
                     LAGAFSLLGSKVSLIVGGIKNLGLAIKALTFDKLVSFGETIYLNTLYAKDFVVNSGKT
                     IAQLGKTALELGKSALAWTAHAAKMGLATAAEFAHSVAAGVATAATWAFNAALAVLTS
                     PITWIIAAIAALIAIGVLLYQNWDTVVEFAKTAWQGLCDFISGICRAIGEFFSGLWTK
                     LQEIFEPIGQWFGEKFQQAWDAIVNIFSGIGEWFSGVFQGAWDAIVNIFTPIGSWFGQ
                     RWADVTSALANIGAWFTDIFQKAWTGLTNIFSKLGLWFGERWADVTSVLANVSSWFGN
                     MFTSAYNAVKNAFSSIGGFFSGVWSTVQSIFVNAGQKVGSAVGGAFKSAVNAVLGTIE
                     NVVNGFIGMINGVLGVVRNLPGLGWVGSVSTVSLPRLARGGIVDSPTIAMIGEAGKEA
                     VVPLENTGFIQTLGRVVSSAVVNAMAGISPQGGFSSDGDIVIQIAGHEFGRVAIQEIN
                     KEHERAGQTLLKI"
     gene            24766..25116
                     /locus_tag="VVO77_001360"
     CDS             24766..25116
                     /locus_tag="VVO77_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693369.1"
                     /translation="MAQLTINGVAVKPPKSFQVGIQDIDGETGRNANGDMVRDRITTK
                     RKLDCEWGMMTQGEISQLLHAVSSKFFEVSYPDPMDGQVTKTFYVGDRTAPSYTFTEK
                     LKPWSGAKFNLVER"
     gene            25121..>27576
                     /locus_tag="VVO77_001361"
     CDS             25121..>27576
                     /locus_tag="VVO77_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HEU5693370.1"
                     /translation="MDALTRRQFDRAMFAKERTLAIRVGEYASRDIKEASFEYGYIKG
                     DTYKPGGTCAGSGKITFTSIITTFNKLDTLHPEIGLLVGDTYQWVKMGEYFINDIEID
                     RNRNTTTLELMDGMFKLNREYVTDLHFPAEVREVIQEICLKTGIELANDYFGISAMRY
                     HIEQVPEGKKLSFRDMLSAMTQMIGMSCFFNREGKMEIRDLTESNITINADSYFLHGL
                     TKSEIEYQIAGITCKTDKKSLTVGMTTGRSLELDNVFITQSALNDLYYKLKNLTYYPY
                     NLNYQGHLLLEVGQWVTIQTNKKETFKVPVLSQSFIFKGGLRGRISADSKAGNDTQYS
                     YEGTITKQIKQQDGFEAKIQAQIEAADKDFDQKVDKIKKDFNDQVELAKARAEEVKRE
                     LSDTINQRFNSFDNGPLKEAKRKAEEALRNAGASSSLAQESKRIGLDSVARLEAFKSQ
                     TTSAQTALSGDLDALKRTIANDIRPKQAQAEAEIAKQVEALSRTKNELDGASTLLAQE
                     AKRIELDSVARLEAFKSQTTSAQTALSGDLDVLKRTIANDIRPKQAQAEAEIAKQVEA
                     LSRTKNELAGVKSAQATYEETTTRRLSELTNLANGKASKSELTQTAEELASRIASVQA
                     SGRNLFLNSLFKQDISKTGIWTTSTYTATIDSESKYLGYNALKIIGLNPSGRDGGNPK
                     VTYPVLGQFGKVIPGSTTNQDVTISFYAKANKNGIMLRSRLGNIGYKTGNVTLSTEIK
                     RYVVHIPKGWTNESKQTTNEWLFNFNQEGTVWIWMPKFEISDVDTSYSEAPEDIEGQI
                     STVESTFKQRVNSLEAGVNRL"
BASE COUNT         9079 a         4745 c         6497 g         7255 t
ORIGIN      
        1 tctaataagt actaactata caacaagtac taactataca ataatctaag cctaacggca
       61 ctaacttagt aataactact aacttacaac aaactaatac ttctctaaaa aataaaagag
      121 agaaatttca attttaggac tttgaaaaat aggaaaggag aaaaaatgag accaagacga
      181 tatccgtata gtgggaaaaa agagtccacc tttgtaaagg ccgaccctga gttagttgaa
      241 aaacttttaa gaaacactag ttatcttgag tgtttacaaa aaaagcctat caattttcag
      301 atagactcag aagaatttaa gcgtcttagc tatgaagcca ttcatgatac ttctcaagta
      361 actcaatagt agttattaca gaagtcaaac cactgacctt ccccagttgc aatccgtctg
      421 tatggtcaat ctgtttagta gcttcattag ctttagcaga gatagcttgc atatcttcag
      481 ctgttaaaga ttctcgaaaa tctttaaagg atttcataaa aactcctcct ttctattgga
      541 attttgacta aaacggtgag aggtcctagt cgagattatt atagcaattt aggaggatat
      601 tacatcggtc ttgaggctga tttttggagg caatattgga agataaaatc atagaacttg
      661 ctgactactt catcagcgaa tctacaacgt acagagaagc taaaatagcg tgtgagaagc
      721 tattgaaaca agtcagccat gagatagaac tcagggcaat ggaaagtaag acagtctaga
      781 agacaacaaa aagcacctga cggcaatcag gcgcatacta aaaaacttta caagaggatt
      841 ataacatgaa tatgaactta aatacaaatg aaattttaac aactactgaa tatgatattt
      901 ttcgcaaaat tagtaataga aaaataactg aaaatcctaa attggaagag gagctacttt
      961 ctgagggaca acgtcagccg attttggtaa atgaaaaaat ggaagttatc gacgggcaac
     1021 atcgtcttta ttacttgaga aaacatagaa aaccagtgcg ctacataatt gatccgaccg
     1081 ctaatttcaa gacagtaatt tcgatgaata catcagctgt caactgggca ttacaagatt
     1141 atgtgtattc gttcgcttta gagggagatc ctgaatttgt taaattagct aaatttttag
     1201 acgagaacga attgcttagt gacaagatgg taatcgtagc tggttcagga agacgtgatg
     1261 gtacggcagc acacgtagtc aaaaaattaa aaaaaggcga ttatgtattt tcaaacgaaa
     1321 aacagttaag agaattttgt aagttctacg aacgcgtttt aaacgaaaca aaactgccta
     1381 acaaaccatt tttacaatct gttttatgga ctttgtatac aacatcagtt tttgatgaaa
     1441 acagaatgtt gacacaattg aagaaatcag atttgacatc agaagatatc gaaggatttg
     1501 caaagaaaaa attgctatta acttttttag agctatacaa cggaagatgg agtgacgatc
     1561 atccttcttt aattcaatac tttatcaaca gaaaagggtc gttaacaatt cctagtttgc
     1621 ctaaacaaga tgaagataat taaaaaagta ggaagataaa atgaaagtca cagtatatgt
     1681 ttacggccga aaattagaac cagatgaacc aattatcatc ccagaaaatc atcgttttta
     1741 tgacatttgg aacggaattg taaatgaaat gctcgacaac gaggaggatg tagcttaatg
     1801 aaactactta ctaaattaaa actcagactc gaaggagttc ttaaatcagt caaccttgac
     1861 tggagagagg tagcagtcga acttatgaac gacctatttg aggagcgcaa gcgtcgcttt
     1921 gctttcgagc aagaaaacta tgacttgaag caggagcttg ctgcctacaa gtacaaagaa
     1981 aactttgata tcaaggctag actgcaagga gaaatgtaga tgtacattat atcgatttat
     2041 gtcaagaata ctgaaactgg aaacgaggat ttcagtttga ttggacgtga tttcttaccg
     2101 acggggcacc aagactatat tgcaagagtt tttggaacaa aagaagaagc gattgattac
     2161 ttaaaatcta tatcttacat cgcatcaggt gttcatggta acgattgggt ttatcaaaat
     2221 gaaaaactac cagaaattga gtcacgttgc cgaatttgga aagtaggaga ataaaaggag
     2281 aacaatatgt ttaaagcact aaaaacaatc aaaaaaatca aacaacttca gaaagaaatg
     2341 cacgctttca gccttgcgtt tctagctcta caagatatgg gcttgatgcc agaaactgaa
     2401 agaagtaagg caaaggctca aacaatgcac gatgtaagcc gcgtactcaa ggacgtcttg
     2461 gacggcaagt cggtagatga agcgataaag cgtctaaata gcgaagtgaa agctgaagag
     2521 gtggggcaga aagatgacca gaattgaact tgaaaaccgt gtatggcttt tggctaatca
     2581 tgaagaaaaa aacgaattgc tggatcttgg gctaacgtca aagaccagat atgtgaagcg
     2641 agttctggaa ctaggaaagg tgtatgctca tgtttgatta tgacagagat ataatgcaac
     2701 cgcctgaaga acgagaagaa cgtgacccag ctgattggat tttcagcgct ggtcaatgga
     2761 tctatgtagg agattgttag cctatgaata gagaacacaa cgaaaggtag aaggaaatga
     2821 cgaataatca aattgtagaa gcaaaaggcg actttttaac caacccacag ctacttaata
     2881 gcggtattat cagaaagtat cttgacccac aaggaaaagc tagtgatgag gagcttgcct
     2941 attttatagc tcaagccaaa gcccaaaacc tcaatccatt tacaaaagaa atttatttta
     3001 tcaagtatgg aactcagcca gcccagatag tcactgccaa atcagctttt gaaaagaaag
     3061 cagatagtca cccgcaattt gatggcaaag aggcaggcgt aatctatctg atggatggtg
     3121 aaattaaata ctcaaaagga gcatttattc ctaaaggtgc tgaaattctt ggcggttggg
     3181 ctaaggtgta ccgcaaagac cgtatttacc caacggaaac agaagtatct tttgaggagt
     3241 acgacaattc taaaatacgt gcaagagtta aggaactgac acaacaaggt aaagatgtta
     3301 cttatccagt gatgaactca tacggtaagc caataggtga gaataattgg gatactatgc
     3361 cttgtgtcat gatacgaaaa gtagctctag tgtcagctta ccgtgaggcg tttcctgccg
     3421 agcttggagc aagctatgag gctgacgaaa ttcagctgga taacacacct aaagacgtca
     3481 ctcctcaaga aagccgtgag gatgtcgtag cacgcaagat ggctcagatt gatcaattca
     3541 acaaagagca agaggcaaat catgcagatc ctgaacctgc taaaactgag gagccaatcc
     3601 agggcgagtt gctagacggt gaacttgaat attaggagga caacatgcaa gaattacagg
     3661 ttattgatga taagaaaatc aataaaatct atgagatgat cacaacggat gaacttacta
     3721 gagagtcttt tgaaaaagac ctcatagagg ctactgagaa gtacaaggac tatattccta
     3781 cagctggaac tctcaaagac gacaaggcaa agcgggctga atttaacaag ttaattgagt
     3841 ctaaaaatcg tatccgtatt gacactaaaa acttactatc agagacagct aacacatggg
     3901 atagttatgc taagtcaatt attgacccat ttgcaaccgt agttagtgaa tttgacaaag
     3961 gtatcaagga aatcgaagaa catcaaagac aactaaaaat agatacggtt aagagttacc
     4021 tagccaacaa atcagctgag tacatgctgg atcctcgtct ctttgatgaa aaggcccttg
     4081 agtatgtcaa agctagcgat tttatggcag atggcgtgac gcttaaaaaa gccactatga
     4141 agtcacttga tgacatggtc acatttgaat ttcagaaaca acaagaattt gaaaaagcca
     4201 agtcagctat ttcagggtta tgtgctgagt acggcatgac tgactcacct tacattagac
     4261 agctgaaaga cttgactctt gctgaagtct ttggacaaat caaagctgat tatgagtttg
     4321 aaaagcaaaa ggaagaactc agacaggatc tagaacgagc agagcgatct aatcaggagc
     4381 ttttagcagc ccaacaaacc aaacagcaag aacaggctcc aaaatcaacg gaaaccccaa
     4441 attttgaccc agaaacgggc aaaatcttgg acggtggaca aatcctccaa aatgagccta
     4501 acgctcttag aggggctgaa aatgacctaa aacgatatgc ccaaaaaatg actttagagg
     4561 tgtattttgt agacacagcc gaaaaagacc gtttcaaggc tggtctaagt caactcggat
     4621 ttgattttaa aaagaactat caagtcaggg gttatcaacg tatcgatcca ttaactcagg
     4681 ctgagctaaa tgaacaatgt gggtggtaag tatgacagaa attgaaaaaa tttcagaaga
     4741 attggctgaa tatggggtgc ctgatgagtt aataggaaaa atagaggacc tattagcgac
     4801 tctgtatggc gaaaaaagga aattggagat agaaaaatct tgggatattt ctccagagtc
     4861 aatggggagg gtaaccatgg acatcagaaa aatatctgac agcgtagcca tctactcgga
     4921 cggcaagaaa ttgcaggtta tccacaacct aggggatgag tttatcctag attttaaggt
     4981 gggagaggat agcgtctgga acctcaatgg ccaagtcgta gaaattattg acatgattga
     5041 gcctgtcttt aaagttttca gcttttgctc aaaatctgga gagggtatgc aacgcttaaa
     5101 acatgctatc gttcactttg aaaaatttga gcagtacatc agagataatc aggaagacct
     5161 gatgatctgg tggcacaatc caggagggga atatgattaa aaccgtattt ttttcatgtg
     5221 attatccaca tcatgaggtg attgacgacc aaataaatag ttggcttgcc gaaaatccag
     5281 gcattaagtt gattgacatc aaatttcaat caaatgtgtc tgctgtcgct gacagtggag
     5341 tcagtgctga atattggcat acatccgcat tgattattta caaagttccc tcagagaaca
     5401 atataagcag tattaattca aatggtttag gtttcataat cagctgtgag aaatgtggta
     5461 gcttatcaat aatcaaggga aaagatgtag gtcaaaatgt atgttatgaa tgcaaaggag
     5521 agaaataatg aatgatttta tcaaagagat tgggatggct atcctatgga tgtttttagg
     5581 gtatctcttg ggagagcgta gcactagagg gggacaaatc agatgatcaa taacgtcaca
     5641 ctggttggga ggcttgtagc gcctcctgat ctacgaaaaa cgcctaataa tgtatctagt
     5701 ttacagggca cgcttgcagt caatcgcaat ttcaaaaacg aaaatggaga gcgtgaggct
     5761 gattttatca atttccaagc gtggagaggt acagctgaca tcattgctca gtattgcagc
     5821 aagggctcac ttattgggat cattgggcgc ttacaagtta ggtcttacga gaaagacggt
     5881 cagcgtcgat atgtgactga agtaatcgct gagagtgtag ctctgctaga gagtcgcaac
     5941 agtcagcacg gacaaggcaa cagtttccaa aatgggaata gctcaccttt taccgatcct
     6001 aacccctttg acctcccaaa tgacggtttg ccgttttagg agggacagtt agtggaaata
     6061 gataagatta taaaaaaaga tgtcttggaa tttatggaaa caatttctga taataaaatt
     6121 gatgcaagta aaatcaatgt gacagaacgt attgctatca tcattgagaa acaaaaaata
     6181 gaggtcgtta cgactctaaa ctatgatatg agcattagct ttgataacaa agacacggct
     6241 cctacactag atgacaatgg tgaccttttt gaaccggtct acaagtgcaa agttaaggca
     6301 attcccaaaa atgatgtatt tttcacctca ttaacacggg tcaagagcaa taccaagacg
     6361 ttacaagagg ttaaaaaatt ctttgagttc gtaaacgaaa acagagaaaa tctctttgag
     6421 atggcaggat ttaagggggt tcttgaatga aattgaccct gaacattgag cctaaacctc
     6481 aatcacggcc aaggtttgca agacgtggga gttttaccac aacttacgaa gacaaggata
     6541 tgaaaacatg gcgtaatcat tgccagctgc tcattgctaa tcagtacatg ggtcagccta
     6601 tccttgaggg agctttgagg acacggctta gattttatat caaacctcct cagtacattt
     6661 ctaaagtcaa gaagaaccaa caggccctcc tggatgaaat tataccagta ggcaaaaagc
     6721 ctgacataga taactacgaa aaagcgctat atgacagcat gtcagggatc gtcttccagg
     6781 acgacggtca gatagcgcta catgatgtag gcaagttcta cagtctaaat ccacggatag
     6841 aggttgagat tgaggtcatg aaatccctga gtatttgaag aaatgaggag cagatggctg
     6901 actacgcatt atatcaaggt gatgtgtttg ttacgcttgg aacattagcg cagatcagta
     6961 gcgagacagg aattactgaa aggatgttaa agtattacac ttacacatca caccaaagac
     7021 gacacccaaa cggtagggcc gttattaaaa ttgaggagga agataatgag aattaagacg
     7081 gaaagcggag gagttggaag atgatggaag agttaaagca aaaagttaat gaagtataca
     7141 actggacggt agaagacggg aagccgcaac ctcccaagca agatttacca caagcggtga
     7201 aagaccgggc ggactatttt tgggaaatgg cagaagatgg tatgacgttt atgggagcga
     7261 tggaatgcat cttcgctgat gaaaagccta tagactatga tttgggagct actaaggatt
     7321 ggttgccaaa atctaaggag tttgatgatt gggttggtta ttcgccaagc atggctcagg
     7381 tagttattgc agtttatttg atttatagag gaaactaaga tgaataagca ggaattgatt
     7441 aaaaaattag aggaacgaag aacaataact gggaattttc aaggttatgt agtttggtgg
     7501 aaggatgtaa aagaaatctt tgaacaacta gacgaatccg aaataggtca cgcagatgaa
     7561 gctccacgct acgtaaagaa catactagca cgattgcgag aattgccatt gcatgataga
     7621 gaggtttggt taaaggctat catgagcgaa tttgaacagg attttagccg tgcaaaatgg
     7681 cgagagggct acgagcaagg taaaattgag ggtatggttg aacgtgaaaa agtcatagtt
     7741 ccgcagtgtg tggcggaata tatagaattt aaaaagaaaa acaattttca tgtttacggt
     7801 gcaatgagag taattgaaga tcattatgat aagaaagttc ctgattggtt ttacgaaaat
     7861 aacatcgaaa aattctgtct tgcttggctt gacggctacg aggttgaaaa agagaagcgg
     7921 tattttgtta agattaaagg gaatattaaa gaaaatatgt tggtttatgg agaacttttg
     7981 aaaaggtatt tctttacaaa aagctttagt ttagacgatg ttatatattc ccacacccgt
     8041 aaagaactag aagacgcaaa gttcggctgg gtgtttgatt gtccagggat tgagattgag
     8101 gaggtggagt gatgagcctt acgctaaata gcacaattgg agacttagtt ttggcaatcg
     8161 gagaaattat cgttggttct gatggtaaaa ccactacagc gatactggag atacctgatc
     8221 aaagctttta cttagagatt gagcttaaat tgaaggagga ggtcataaat tgaaacgatt
     8281 catagctatc tggattctgc tatctgctgg attgaatatc tggcagatgg acaggattcg
     8341 agatttggaa gagaagaagc cgatggttat ctacaaggct gataacgcag gcgttgagat
     8401 attcggtaaa gtcgtcgaga aaggacggca tggcaagcta tatacgctaa cgatacgtga
     8461 ctatggtgtg ttcgtggtta cgaaggacgt gtacgataaa gtgaaagttg gggatgaggt
     8521 gttactatga cagaaactat taaactacca gactattatg agcctgattg gaaaaatgca
     8581 aggtacgggt cgttggaaga gcttaaagaa ttgttgctct ttaagcgtat tgtgaaatgg
     8641 gataaggact ttttgctgct tgaagacggc acaaaggtca ctattgaaat gtctgaaagt
     8701 gattgctgtg cctcagcagg tggggagttc caagatgtat cacttgacgc tgtgattact
     8761 aatattgaaa ttggagaacc ggaagaaatc cccgaccatt ggggaactgg ttataaaaac
     8821 aaagtaacta tcttccataa tcagaaccct gtagctattg ccaattgtga agcagagcat
     8881 aacggctatt attacagcgt atgctcttta gtgattggtg atattcattt tccagttgtt
     8941 aatgcttagg aggatttggc atgataccga aatttagagt gtgggtaaaa ataggaaaac
     9001 gtatggtttt ttcagatgac attcttgcta ttgactacga aaacaaagaa atagtgacac
     9061 aacaagttta ttttgagaat ggtttaccag acgatagaga tatctattgt tatgattttg
     9121 acgaaatcga actcatgcaa tcaacaggac tcaaagacaa gaacggcaag gaaatctttg
     9181 aaggcgatat tgtacgaact actagatttt tgggtagagc tgacgaaatt ggcggtttct
     9241 atgagtatga caaggaattt atagggattg ttaagcagct tgagggttct tgggtaattg
     9301 atacgggcag tgacgcagta tgtttatgga ctgaaattga agaaaatgaa atcatcggca
     9361 acatctatga aaataaggag tttggaggac gcaaatgaga ccttgtaaat atccatattc
     9421 aggaagaaga aaaaaacaag aaacgccgtc gccaatattt tctgcacgac caatttttga
     9481 cgaagttcca attgtagaag aagttaaggt tgagttcgga gttgaagcta gtatggggcg
     9541 catatatcca gaaacgttaa tacatttaga tatttctgga tacggaaata gagtgcattc
     9601 agtacatcgc ttccccggta ttttactgag tgttggtgag tcaatccaac taaagatgct
     9661 tttctataaa agacttagaa attttactac agatcgtttc ttgacgttta gagaatctga
     9721 ttggaagttc tttatccggg acctggtcaa cgaatttaag cattaaaaaa agccaagaca
     9781 ctctctgcct cagctaatag ttctcgcaaa gactattata tcacaaagga gacagagagt
     9841 gaacaaggct aaagagctct tgaaagagtt gcaggatctg gacatggaca tccaaagccg
     9901 tatagacgaa attaacgagc ttgaggcagg tttgctctca agccctaaat ggtccgaggt
     9961 taaagtccaa ggtggacaga ctagaaaagt tgatgatgtc tatactcagt tggtagtgat
    10021 gaaagaggct atagagcagg atactaaaga ggtcattaac agaaaacttg aattaggtag
    10081 aatgatcaat aggcttaaaa atccaaagta cagggcagta ttaagaatga cttacatcaa
    10141 caaaggcacc gctgatagcg tttgttatga tttgaatatg agtcgtacaa cctactacag
    10201 gttaaaaaat gaggcggtct tagctttgga agaagttatc taacctcata gtgagcttat
    10261 gggacttttt ggaacagcac ggttctaaaa atctgttaga atggtagtat caagaattga
    10321 aaagagaggt ctcagaattg gtagatggtt acctgtaatg tcagggggct gtaatggcct
    10381 tggaggttca agtcctcccc tctcctttga gtgtttgtgt cccagaatga gttaaatctt
    10441 ctgggtgggg attcacatat cactcattaa ctcctatcac tcattaactt aaaaatggtt
    10501 gcggaagcga ctggacctcg catgattgcg tagctaatta tattccggat aagttataag
    10561 ctagagggtt tgattccctc agaggtttta aagactacaa aaaataaaaa agaagtcaaa
    10621 atttaatacg cacgcaaggt agtagtcgcc ttgcaagaag gtcgcacatc gtgtggcttt
    10681 ttttgattat tcgaagggtg gtgatggaaa attgagtaga ttgagaataa aacaaaagag
    10741 atttgcagat gagtacatca tctcaggtaa tgcgacggaa gcctataaga aagcaggtta
    10801 tcgtgtttct agtgatagag tggcaggcgt tgaaggacat aagttactaa agaatcctaa
    10861 gattaaaagt tatatagatg aacggttgaa acagcttgat tctgaaaaaa tcgcagacca
    10921 gcaagaagtc cttagttatc taacctcggt aatgcgagga gagacgcaag aacagacttt
    10981 gataagcatc ggagaattgg gtcaaacgat tacggatatt gatgttggag caaaagacag
    11041 aatcaaggca gccgaactat taggaaaacg tcataggctt tggacagaca aagtagaggc
    11101 agccgtttct ggaacggtgg tgtttgcaaa tgagtcagac ataccagatt aaacaaagtg
    11161 atattgtaat cgacctacct aagacagtag gagctggata cggacagttc tggcgctcaa
    11221 gaaatcttta tcgtgttgta aaaggttccc gtggttcgaa gaagtccaag acaaccgctt
    11281 tgaattatgt tatccgtctt ttgaagtatc cctgggccaa cttgcttgtt attcgtagat
    11341 actcgaatac caacaagcaa tcaacttata cggattttaa atgggcgtgt aatgtgttgg
    11401 gtgtgactca tttgtttaaa tttaacgagt ctttgcctga aataactgta aaagcgactg
    11461 gtcaaaaaat cctattccgt ggtttggatg atgaactcaa aatcacatct atcacggtcg
    11521 atgtcggcag tctttgttgg gcatggtttg aggaagcata tcaaattgag actgaagaca
    11581 agttcagtac agtagttgag tcaatccgtg gtagcctaga tgtacctgat ttctttaaac
    11641 aaatcacagt cacatttaac ccgtggaatg agaggcactg gctcaaacgt gtgttctttg
    11701 atgaagagac tagccgagct gatacattcg ctactacaac cacttacaaa tgcaatgagt
    11761 ggcttgatga agtcgatatt aagcgttatg aggacttgta tcacacaaat ccaaggcgtg
    11821 cgagaatcgt ttgtgatggt gaatggggag ttgctgaagg tttaatctat gagaacgtga
    11881 ccgtcaagga tttcgataag gatgaattgc tacgagattc agctaataag ttatgtatcg
    11941 gtcttgactt tggttttact cacgatccaa ccgctttgtg ttgttcgttg ataaatgaca
    12001 cgacgaaaga gatttatgtc tttgatgagg cgtataaagt cggattgata accaaagaag
    12061 ttgcgaagat gataaaagac aaaggttatc atcgctcaca aatcattgct gatagcgcag
    12121 agtcacggct gattgaagag ctcaggtcag aacatggcat atctagaata aaagagagtc
    12181 ggaaaggtaa ggatagtatt atggcaggcg tatcaaaatt gcaaggatac actatttatg
    12241 tgcatccaga ttgtaaaaac atcatggatg aattttatag ttactgctac cagcgagata
    12301 aagaaggcaa ctggttgaat aaaccagagg ataaaaacaa ccacttgatg gacgctttgc
    12361 gttacagcct tcaatgtatc gaaggtggga aagcaaccgt ccgcagacgt tctgattatg
    12421 gtctatagag aggaaagaca tgtaccaata tttaacctat ccacgggatg gatatgatga
    12481 gggttctttg aagaaagacc tgatttacaa attgataacg atacatagca ctgaaggctc
    12541 gcatttgaag aagcttaaaa gctactattt gggtgagcat gctatcttag aacacacgag
    12601 acgcaacgtg aacgcaccta attacaagac ggtagccaat catgccaagg atatcgcaga
    12661 cacggctacg ggctatttta tgggcaatcc tatcaagtat aacaatactg ctgacggtga
    12721 tatcgatgaa ctacttacag cctttgatgg tgctgagatt gaccaagtag atgctcagaa
    12781 tgctttgaat atggctatct atggtcgtgc ttacgagtac atctatgcta aagagggtat
    12841 ggctgagttg gattcaacta gtattgatcc ggagaatact ttcatggtct acgatgatag
    12901 tattgagcgg aagcctttgt ttgcggtcta ttactatgaa gtaaaagacg atacgaaaga
    12961 cactaccaag caccaggctg aggtctttac cgaaaatctg cactatcaca tggtgctgag
    13021 aagtacagat tcaggaacaa ttcagagcga ggaggcaaca cctcacaacc ttggtcaaat
    13081 cccaattatc gaatatcgca acaatcactt tgcaattggt gactatgagc aacaaattag
    13141 cttgatagac gcttataatt ccttgatggg gaatcgtgtc aatgataagg aacaggctgt
    13201 agagtctata cttgtcttgt atggcacgca gttagcagac actccagaag acgctaaggt
    13261 agcaatgaag attctttctg aagaaggtct tttggaattg ccgggcgata gtgcaagggc
    13321 tgagttcttg aagaatacgc tggacgaaag tgctactgaa atcttgcgta cagctcttaa
    13381 agaggacatc tacacattta gccatgtgcc taatttgact gatgagaatt tcgcagggaa
    13441 tacatcaggc gtagccatgg aatttaagct gatgggcctt gagatgatta ctaagaccaa
    13501 ggaagcgaac tataagcgag gattgcgtca gcgtattgcg atttttgctc attacttagg
    13561 catgaagcag attgctttag agtctcattc aatcgttcca caattcagtc gtggtttgcc
    13621 taagaacttg ttagaaatct ctcagattgt gaacaatttg gaaggcaaag tgaccaatag
    13681 acagcttatt tctctcttgc cgtttgtgga agaccctgac gctgagctgg aagccttgga
    13741 agaagagaaa aagaagaaca tggaagacat gccgatgttc aacaaagaca acacgaaacc
    13801 cgaagacgag gtagaggatg aagaatcagg agtattgggc gaagaggaaa gccaatctga
    13861 tttaccagca gatggacaag gccgaaaagc aggcagatca gttcgataag gtctatcagg
    13921 aagccaagac ttacttggat aaggaagtca ataagatttt tgataagttc caacgtgatt
    13981 atggtctaag tcaggtagaa gctagacaag tcttgaagaa catgaaagac aagaaaaatc
    14041 tgaatgaact tcgtaaagta cttgaagcga gaccgaatga cccgaacatc caaagattac
    14101 tagctgactt agacagccca gcttattctt tccgtatgaa gcgcctagag cgtttgagcg
    14161 acgatttaga ccgtatgcgt gaatctatct atcattcaga gaagacaggc tcagacgcct
    14221 tttatagcga cctgatgaag gatagttact acaaggctac ctttgacctg cagcagcaga
    14281 caggactagc atacggcttt tctgggcttc ctgagagcga gattaaacat ctacagtctt
    14341 ttagttgggt aggagatgga agtacgtact caacaaacat ctggaagaat acagggaagc
    14401 ttacatcaag cataaaagat gaattactca taagccttat gacaggccga gatacacgag
    14461 aaactgcaca agcaattgct gagaggttca atgtaggtca gaacgatgca agacgtttgg
    14521 ttcggacaga atcagccttt tttcataacc aaatggaact actcagctat gaagaagcag
    14581 acatagaaaa gtatatcttt gcggccgtct tagacaagcg tacatcacgg atttgtcagg
    14641 agcatgacaa tcaggtctat gatagggaca aggctgtccc tggcgtcaat tgtccgccta
    14701 tgcacccttg gtgtaggtct actactgtcg gatacgatga ggacgcagat tacagcaagt
    14761 tgaagcgcag agcaaggaat ccagagacag ggaagaccga gctagtacct gctgatatga
    14821 cttataaaga gtggtatagc aagtatgttg cgaaagacgg ggaaaaggtg tataatcaag
    14881 atacaagaga agccaaggcg aaattttata gcgaacaact attgtccaaa atttcaggag
    14941 ttgagccaaa aattacaagt gatatgcaac gtatcgcagg agaaaacaaa ttggcaggtc
    15001 ttgaatttag gaagaaaaca gttgagtcat tatcacgtaa aattattgca gatagcctag
    15061 ttgaaaatat aagtttgtca aaagccgtga gtaagattaa tgacgcctta aggtacacaa
    15121 ctattttcga ttccgatact tttacagaag agtatttgaa gatgaaacag aagcttatcg
    15181 cagaaggtta taaaattgta aaagtaaaaa acacttggcc agtagatgga ccatacaaag
    15241 gtgtgaatac agtcgttgaa aaagatggta tcaactttga aatgcagtat catactcagg
    15301 aaagtttcga cttaaaaaat ggttcattac atgaactcta tgagaagtat cgtgatacga
    15361 atacatctga tctagaacgc atgaaattat ttaaggaaat gcttgattta agcaatgggc
    15421 ttgagattcc taaaaatata gagagggtga agtgatatga aagatattaa atactaccgc
    15481 acaacgacga acaatgctca agtacttcgt ttgattgatg gtgtcatgca agtttttgac
    15541 attgaaaaaa agtgggttaa tagcatggat tggtttaata aaatcttttt taatgacttt
    15601 acggattttg aagaaatttc agaaaatgat gcatttactt atattgacag gatggtagcg
    15661 gcatgattga tattgccttg gctatcgcta aaaaagcaca tgcagggcag gtagataaag
    15721 cgggtgttga ttacatacag catcctctct atgtggccag tcaagtcaac actgaacaag
    15781 aaaaagctgt cgctctttta catgatgtga ttgaggatag cgatataact gctgccgatt
    15841 tattcgcgtc tggcttgtca aatgaagttg ttacagcggt acaaattttg acaaagaaaa
    15901 aaggtcaaag ttatcaagaa tatcttggga aagtaaaatc aaataattta gcaagagttg
    15961 taaaacttgc agatttgaaa cataactcag atttatcacg tttgaaatct gttaccaata
    16021 cagactacga gcgtgttaaa aaatataaaa atgcaattta ttacttaagc acctagagaa
    16081 atctaagtgc ttttttcgtg ctcagaaagg agaatctgat gaacaagtac aaaaagttga
    16141 tagaattgat tgaaaataac ggtcttgaga tacaatctaa gaaatgttat gatccacaga
    16201 gtgcttggca tggtgaggag ttatggattg ttgataagaa aaaacaaaat aaaatttttg
    16261 atttatcagg taacggttac tgttttcatg acgctaaagt tgaggaagcc attgaagaag
    16321 ttgagaagta tctattattg aaaaagatgg atacgtttga tgatttcaaa aaatgggtgg
    16381 aaaagaatgc taagcctaaa aaatgatgct tagaaaggag tgaagatatg tttatttggg
    16441 attgggtatc aatcgctttc gggtggttgg tatttttgtt tttaatgcta tttatcatag
    16501 cgtttgtgaa aaaagtaatt gaagaaatca aaaaataatc taaccgtatg gaattccgta
    16561 cggtttttat attgtccaaa ctgtaccgat gacattaaaa gctgtaccgt tccgtcgccg
    16621 gacgtaaaac gagattatcg agtggcgacg taatcgctgg aggacaatta tgtcagaaga
    16681 aatcaatgca actgtatcta ctgaatcaac tgagactgtc gacactcaag aaaatgttga
    16741 tacggtgcag gaagaaaagc acgaacgaac tttcactcgt gctgaaatcg gtaagatgct
    16801 atctgccgaa cgctctaaat gggaagctga gcaagaagcc aaggaaaacg aagctaagaa
    16861 acttgccaag atgaacgctg acgagaaaca gaaatatcag ttggatcagc gtgagcaaga
    16921 actagctgac cgtgaaaaag ctattgctcg caaggaattg accgcagaag ctaaagcaat
    16981 gttaagtgaa cgtgacttac ctgttgagtt agtaaatgta gttgatttga caagcgcaga
    17041 gacggtatct gaatctatta cctctatcca aaaagcatgg gaagagtcag ttcagaaggg
    17101 agtttctgaa cgtatgaaag gtagtgcacc tatcaaaaat gcacaaacag tccagcaaga
    17161 agtcacggaa aaatggcgta aagacttctt gtaataaaag aaaagaggaa aaataaatgg
    17221 catttgaaga attaaacaca gcagaatcac gcaagaaaca tcttgggatt attgaggatg
    17281 tgcttgcggt aaattcatat tcaacaccac ttgtaacatc aagcgatgca gtaaccttgc
    17341 aaggtcgctc ttttacagta gcaactggta acacaacaga gttgaaagac tacaaacgta
    17401 acaaagacaa cgaatttgat cacgttgaag ttgaagaaaa ggtttatacc cttgatgaag
    17461 aaaaatactg gggtcgtttc gtagatcaat tggacgaacg tgactctaat ggtcaagtga
    17521 atatcaatta tgttattgcc cgtcaggctg cagaagtagt cgctccatat cttgatgaac
    17581 tacgttttgg tgcagcactt ggaaatgtaa gtgacaatgt tgccatgggt aaaacagcag
    17641 gagcgaacaa cgcttataat gcggttcttg atgtgtctga gaaacttgat gagcttggaa
    17701 ttacaaaaga acgcttgctc ttcgtcactc caagtttcta caaagcgatc aagtctgaaa
    17761 tcgttcgtct accacatggt gacgcagata agaaagtcct tggaaaagga tatgttggtg
    17821 aattggatga ttacacagtc tataaggttc cttctaaatt cctgaaaggt gttaatgccc
    17881 ttgctactgc tccaggtgtt gttacatctc cagtacaagt agataatact aagtacaacg
    17941 ataacattcc agggcgattt ggcgaattgg tagagcaatt gctttacact ggtgcatttg
    18001 ttcttgaaca cttcaagaaa tacatcatca caattgcaga ttctaagcct gctgctaaac
    18061 catctactca aggtaaagtt gtaaaccgtg ctaaagcgtg gaaaactgga acaacctaca
    18121 aagaaggtga cacagttact catgccgata aagtctatgt agcggttaag gatatttcta
    18181 attcatcaac cgcaccagac acagatacaa ctaactggaa agaaaaaact ggtaagaaat
    18241 aggtccgagt tatgaaattt aaaatcaaac aagatttcta tgattgggaa tcaaatgtga
    18301 aacgactggc aggagaggaa cttgagatta ctgaggagcg ctatgctgaa ctggctgaca
    18361 atattgccag caacggtgtc gctatctcag atgttcttga ggaaatcttt cctaaacctg
    18421 agttcttaga agaggattga tatgtctata gagttgctga agaaattaac aggcgaagaa
    18481 gatactcagc ttctcatgtt gctccaaaca agggctacaa atcttatctt gtcagagact
    18541 aatcgcacat ctttgacacc tgctttaagt cttttaatac ctgaggttgc tatcgaactc
    18601 cacaaccgct caggagcgga aggagagcat tctagaaccg agggtggtat agcagtagtc
    18661 tacggagaaa acggcctgtc tacggatctt ctacagcgaa tacgcatgca caggctagca
    18721 agggtggcag gtcatgtttt tgaagcagag tagactgaaa ccttatccaa tgcgacggtt
    18781 tgaaaagact gtcactgagg aaggtgtcgc gaaagaaggg tatgccaagg aagctgagac
    18841 agtccgcctt gaattgtggc cagctagtag caagctacaa tctgaattgt atggcgagcg
    18901 tgtcaatgat attttgaacg caaatgccaa caagtcagct actatcaaag taaaagatgg
    18961 tgtgtgtatc gatagtcaga cggaagtgac tcatagggtt atttctaaaa aggtctacac
    19021 acatcatcaa gttttggagt tagagcgtgt cagggctact aggggcagat aggcttatag
    19081 ctaaatgtag acgattggct agtaaaaaaa ctggcgagga tatcgtctta cgtgcggtgc
    19141 acaatgctac tataaaggtt gtccaagcag atgcaagaag actcgcacca gcgagagatg
    19201 gagagcttat aactagtatc aaaactaggg caaaaatgga cggagatagg gctataggcg
    19261 aagtttacac caaccttaaa tacgctcctt atgttgagtt tggaacggga ccaataggac
    19321 aagctaacca ttcgggtatc tctccagagg tcagcgtaac ttacaagtct aatccttggt
    19381 atgtgcatga agaccaaatc aatgtaggac cgtaccactt tcaaaagatt ggggagttct
    19441 acaagatgta tggtcaacct gctcagcctt atctttatcc agctttgaga gacaatcaag
    19501 agcgtgtgtc taagaatatt tcgaattatg tccgtagaaa gataagagaa caaataaaat
    19561 gattaatatc aagcctgtta tttataaaga attgcaaaag gttgcagata atgtgaccga
    19621 tacttatcct agcgattggg agactttccc agtcgttatt tttttggaag aacaaaacaa
    19681 gccgggtgat tggtttgatg accaggaaca aaaatcctct atccgctaca aggtggatat
    19741 ctttgatgat accagcacta gtgagttagc tgttaaaatc aatcagattt ttgagtcttt
    19801 aggtttgcga agaactgact gccaagacgt gccagacccg tctcatttga gacataaggt
    19861 catgcgtttt gaaggtatcg tcgacttaca ctcagagctt gtttttcaat ttagaatgga
    19921 gaattaaaca tgttagcaaa tggaattacg ctttcttatg gcgaaacaaa agatagctat
    19981 actaaacttg ttggattgaa agaagtacca gagtttggta ttgaactcga aaaagtagaa
    20041 aatactactc ttgaagatac ggtgaagaag tacgagtttg gtattgggga cataggagaa
    20101 cttgagtaca agttctctta taataattca agcgcaactg ctccttatcg tgtattgcgt
    20161 aaggcagcag acgacaagaa gaaactctac tttgaacaag cttatccaga cggtactaag
    20221 gtcatttttg aaggccaagt atctgttaag cttggcggtg gcggtgtcaa tgccgttatc
    20281 gatttcacac ttaagattgc cttgcagtct aatcttacat ttactgatgg tattggaggt
    20341 taattaaatg gcgttaaaat acacaacttg gaaagttact gacgaaaaag agttgaagct
    20401 acgtttgaca tctcatcaag ctgcaactgt ggaagaaaaa atcggcatga acttgctgaa
    20461 gattttcatg cctgaagctg gcgaagagtt cactttaccg cctttgaaag ttatgttgtt
    20521 gttagttcac ggagccttgc agcagtatga acatgggtat tctcttgagg atgtctatga
    20581 tttatacgat gaatacgtgg acaatggcgg agaccaaaca accttcatga cagaggtgtt
    20641 gatgccactc tttgaagtat cgggttttac tccacgagga agcaaggaca agaaaacttc
    20701 caagaagaaa atgacagtag acaagtaatc ttaacggtaa ctcagattat tgagaggctt
    20761 tatcctatgt ttttggacat cgggggcaag cctcttgatt tttgggattt gacggtactt
    20821 gaaatcagag aaatgattga aagctataac cgtgtcaaaa tccaagagcg taaagaaaag
    20881 attattgact catacagact ttcgcagatg atatccaacc acgtttcttt attgttatcc
    20941 aaagatgcca aggcctttga gttctgggaa tatgcgcctg agttgtttgt agaagaacaa
    21001 caagcagtag aacaggaacg acagaaacaa gcacttttgt tgcataagga acggatgcgt
    21061 gaatttgcag agagacataa tcgaaaaagg aaggaggaag taaatggcaa ctcttgatga
    21121 attgaaagtc atgattgacg ctgagatagc gcctttcagg aagaagatga aagaagtcga
    21181 gaatcaggtc aaaggaacat ctgaccaagt gaaaaatgct actgccaaag ttcgtgaaca
    21241 gtcgagctca atcggtagtg cgtttggcaa gctggctaag ttcgctggtt ttgcaatcct
    21301 tggtaagaaa ttacttgatg ttgggatgta ttcaacgcag acggctcttg aagtatcagc
    21361 gtctatgaac caaatcaagc gacagatggg cgagagttcg caatctttct taaaatgggt
    21421 taacgataat gccaacgcta tgaatatggg tgtgggtgag gctaccaact acggtgcagt
    21481 ctactcaaac ttattttctg gatttatcaa agataccaac aagctaagcg cctataccgc
    21541 taagatgttg cagacatcgg cagttgttgc tgaaggttca gggcgcacga ttacagacgt
    21601 tatggagcgg attcgctcag gtttactagg gaacaccgaa gcgattgagg acctaggaat
    21661 caacgtcaac gtggctatga ttgagtccac tgaagccttt aagaagttcg caaacggaca
    21721 gagctggcaa cagttggatt accaaaccca gcaacaaatc cgccttatgg ctattctgga
    21781 acaggctaca gccaagtatg gggatacctt gtctaattct gtaaatggtc gtatcagcct
    21841 atttaagtcg ctgatgaagg acgcagcatt gaaccttggt aactctatgt taccgattat
    21901 caatgccatt atgcctgtct tgaactcttt tgctatggtc ttaaagaacg ttactgctaa
    21961 actcgctgag tttatcgctt tgatgttcaa caagaaagca acagtgaaag atggtgttgg
    22021 tggagcagtt ggagacatgg gtaacgccat gaaggatgct gcaggcggag caggagacct
    22081 tgctgacgca gtagacgacg ctggagattc agcaggagga cttgctgaca atcttggaga
    22141 ctccgccaaa aacgctaaga aggccgctaa agagttgcta ggtcttttgg gatttgatga
    22201 gattaacatc ttgcaaaaac caaaagatga cgacgcaggc gggtctggag gcggtggcaa
    22261 aggtggtaaa ggaaagggag gcggtggcgg acctttcaaa gacatcttgc cagaagtcga
    22321 gttgaccgac atggacaaca aattcaagag catttttgat ggtcttggag ataagctcaa
    22381 agggttgttt gacctcttca agaaaggttt tgatgcagca tttagaccag aaggtataga
    22441 acgcattaag actgccttag accaaatagc taagacaatg ggagaaatcg ccactgaccc
    22501 aagggttgtg aatgccttta accgaatggc tgagaaaatt gcttatgctt tagggcaagt
    22561 gacaggctca ataacaacta tcgggctagg tatcggtgtt ttccttgccg aaagtattgc
    22621 aaatggcctt ggaaggcaaa aagaacgcat taccagggcg ctagtcgctt tgtttgataa
    22681 tattggtaac atttccgagg cagtaggaaa catcgctcag gacttttcta gtactttcta
    22741 cgacgtcatt acctcaactg gtgcggttcg tatcggtagc gctattgtgt caactctgtt
    22801 gagtttgaca tctaccattg ttgaagttgg tagtaaatta gcaggaagtt tgtttaaagg
    22861 ttttgaaaaa gtcgttgtga caagcgctcc taaaatttca tcagtcttcc aaagtttatt
    22921 agatactgtt gcgcctgtat ttgagagcat tgaaaggtct gttaacaaat ttggcgatgg
    22981 cttaagtcgt gtttatgatg aacatgtagc ccctgctatt aactctattg ctaatgcttt
    23041 taacggactg attgatatca tacaaatcct ctgggagaat tcttggcaac cttttgctga
    23101 gtttttatca ggagtattcg gtgttagtat tgaaggaatt tcagatttat taggaggtgg
    23161 ccttttagcc actttgggac tattggcgga tgctattaag ttagtggcag atggtttcac
    23221 cgttttttct gactggtgta aagaaaacaa agaacctatc ttggctttga taacaacttg
    23281 gcaaacgatt aatttcttat catgggctga acaagccggg ggacttgcag gagcattcag
    23341 cttgttaggt agtaaggtct ctttgattgt tggagggatt aagaatctag gtcttgctat
    23401 taaagcattg acatttgata agttggtcag ttttggtgaa acaatctatt tgaacacctt
    23461 atatgcaaaa gattttgtgg tcaattcagg taaaacaatt gcacagctag gaaaaactgc
    23521 tttagaactt ggtaaatcag ctctagcatg gactgctcat gcagcgaaaa tgggattagc
    23581 aaccgcggcg gaatttgcac attctgttgc agcaggagtc gctacagctg caacatgggc
    23641 ttttaatgca gcgttagcag ttttgacaag tccaataaca tggattattg cagcaatcgc
    23701 agctttgatt gctatcggtg tcttgctcta ccaaaactgg gacactgttg ttgagtttgc
    23761 taaaactgca tggcaaggac tatgtgattt tattagtggt atttgtcgag ctattggcga
    23821 atttttcagt ggtctatgga caaaactaca agaaatcttt gagccgatag gtcaatggtt
    23881 tggcgagaag ttccagcaag catgggatgc cattgtcaac atcttctctg gtatcggaga
    23941 gtggttctct ggtgtattcc aaggtgcatg ggacgctatc gttaatatct tcactccaat
    24001 cggctcatgg tttggacaac gttgggcaga tgtgactagt gctttggcta atatcggggc
    24061 atggtttact gacatattcc aaaaagcatg gactggtcta acaaacatct ttagcaaact
    24121 aggtttatgg tttggcgaga gatgggcaga tgttacaagt gttcttgcga atgtatcttc
    24181 ttggtttggg aatatgttta ctagtgctta taatgcagtc aagaacgcgt ttagttcaat
    24241 tggtggcttc ttcagcggtg tatggtcaac ggttcaaagc atatttgtca atgctggaca
    24301 aaaggttggt agcgctgtag gtggagcgtt taagagtgcg gtcaatgcgg ttcttggaac
    24361 gattgaaaat gtagtcaatg gcttcatcgg aatgattaat ggagttttag gcgttgtcag
    24421 aaacttacct ggtctaggat gggttggtag tgtaagcaca gttagcctcc ctcgtcttgc
    24481 ccgtggtggt atcgtcgata gtccaacaat cgccatgatt ggtgaagctg gtaaagaggc
    24541 ggtcgtacca cttgaaaata caggatttat ccaaacactt ggacgagtag tcagcagtgc
    24601 ggtagtaaat gccatggctg gtattagtcc acaaggtggt ttttctagcg acggcgacat
    24661 cgttattcaa atcgcaggcc atgagttcgg acgggtagct atccaagaaa tcaacaagga
    24721 acatgaacga gcaggtcaaa ccttgctcaa gatttaggag gttaaatggc acaattgaca
    24781 atcaatgggg tggctgtgaa gcctcccaaa tcttttcaag tcggtattca agatatcgat
    24841 ggagagacag ggcgtaatgc caatggcgac atggtgcgtg accgtatcac gaccaaacgc
    24901 aaactagact gtgaatgggg tatgatgact cagggagaaa taagtcagct tttacatgct
    24961 gtatcatcta aattttttga ggtatcttat ccagacccca tggatggcca agtcacaaag
    25021 actttctatg tcggtgatag gacagctcct agctatacct ttactgagaa gcttaaacct
    25081 tggtctggcg ctaaatttaa tctggtagag aggtaagaaa atggacgctt taactagacg
    25141 acaatttgac agagccatgt ttgccaagga aaggacgctg gctattcgtg ttggtgaata
    25201 tgcttcacgg gatatcaaag aggctagttt tgagtatggc tacatcaagg gcgatactta
    25261 taagcctggt ggaacctgcg ctggtagcgg taaaattacc tttaccagta tcattaccac
    25321 gttcaataag ctggataccc tgcaccctga gattggtcta ctggttgggg atacctacca
    25381 gtgggtcaag atgggggaat acttcatcaa cgatattgag attgaccgaa accgcaacac
    25441 aaccacactt gaacttatgg acggtatgtt taagctcaat cgtgagtacg tgacggattt
    25501 gcatttccca gctgaagtac gagaggttat tcaggaaatc tgcctgaaaa caggcattga
    25561 gttagcgaat gactatttcg gaatcagcgc tatgcgttac catatcgagc aagttcctga
    25621 aggtaagaaa ctttcgttca gggatatgct gagcgctatg actcagatga ttgggatgtc
    25681 ttgcttcttc aaccgagaag gaaagatgga aatccgtgat ttgaccgagt ccaacatcac
    25741 gattaacgct gacagttact tcttgcatgg attgaccaag agtgaaatcg agtatcagat
    25801 agctggtatc acttgtaaga cggataagaa gtctctgacg gtcggtatga caacaggtcg
    25861 gtctttggaa cttgataatg tcttcataac ccagagcgct ttaaatgact tgtattacaa
    25921 actgaaaaac ctaacttact atccgtataa tctcaactac caaggacatt tgttacttga
    25981 ggttgggcag tgggtaacca ttcagaccaa caagaaagag acttttaaag ttcctgtctt
    26041 aagtcagagc tttatcttta aaggtggtct gagaggtcgt atcagtgcag atagtaaggc
    26101 tggaaacgat acccagtatt cttacgaggg tacgattacc aagcagatta agcaacaaga
    26161 tggctttgaa gcgaaaatcc aagcgcagat tgaagcagca gataaagatt ttgaccaaaa
    26221 ggtcgacaaa atcaaaaaag actttaacga tcaagtagaa ctggccaaag ccagagctga
    26281 agaagtcaag agagaactgt ctgacactat caatcagcgc tttaatagct ttgacaacgg
    26341 gccattgaaa gaagctaagc gcaaggctga ggaagctttg cgaaatgctg gcgcaagtag
    26401 ttctcttgct caggaatcca agcggattgg gctggattct gttgctagac ttgaagcgtt
    26461 taagtcgcag actacgagcg cacaaacggc tctgtcgggt gacttggacg ctctgaaacg
    26521 gactatcgcg aatgatattc gaccgaagca agcacaggct gaagctgaga ttgccaagca
    26581 agttgaagca cttagccgga ctaaaaatga actggatggc gcaagtaccc tgcttgcaca
    26641 ggaagctaag cggattgagc tggattctgt tgctagactt gaagcgttta agtcgcagac
    26701 tacgagcgca caaacggctc tgtcaggtga cttggatgtt ctaaaacgaa ctatcgcaaa
    26761 cgatattcga ccgaagcaag cacaggctga agctgagatt gccaagcaag ttgaagcact
    26821 tagccggact aaaaatgaac tggctggcgt gaagtcagcg caagcgacgt atgaggagac
    26881 gacgactcgt agactgtcag aactgaccaa cttggccaat ggtaaagcca gcaagtcaga
    26941 actcacgcag acagctgagg agctagctag tcggattgcg agtgtgcagg catccggtcg
    27001 aaatctattc ttgaactcac tattcaagca ggatatttca aaaacaggaa tttggacaac
    27061 gagtacatat acggctacta tcgatagcga aagtaagtat cttggatata acgctcttaa
    27121 aattataggt ctgaatccat ctggccgtga tggagggaat cccaaggtta cttatccagt
    27181 tctgggtcaa ttcgggaaag taattcccgg aagtacgact aatcaagatg taaccattag
    27241 tttttatgct aaggcaaata aaaatggaat aatgctaaga tctcgattag ggaatatcgg
    27301 atataaaact ggaaatgtga cattgtcgac agaaattaaa cgatatgttg tccatattcc
    27361 aaaaggttgg acaaacgaat ccaagcagac cacaaatgaa tggttgttca atttcaacca
    27421 ggaaggaacc gtttggattt ggatgccgaa gtttgaaata agcgatgtag atacttctta
    27481 ttcagaagct cctgaagata tagaaggtca gatttcaaca gttgaatcga cctttaaaca
    27541 acgagtcaac tcgctcgaag ctggtgtgaa tcgtct
//
LOCUS       DAVHLA010000028        26251 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVHLA010000028 DAVHLA010000000
VERSION     DAVHLA010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26251
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.028"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            167..781
                     /locus_tag="VVO77_001362"
     CDS             167..781
                     /locus_tag="VVO77_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEU5693371.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGNAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFALILSSVVTGKVG
                     SLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAVLRLVF"
     gene            885..1715
                     /locus_tag="VVO77_001363"
     CDS             885..1715
                     /locus_tag="VVO77_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU5693372.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NSSPKPFNYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYQMAV
                     NNISYTKERAEKYLYAAPTVKDPNVLVVKKDDSSIKSLDDVGGKSTEVVQGTTSAKQL
                     EDYNKQHSDNPTILNYTKANLQQIMGHLSDGQFDYKIFDKITVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAKGQDELKTFVDKRIQELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            1756..1833
                     /locus_tag="VVO77_001364"
                     /pseudo
     CDS             1756..1833
                     /locus_tag="VVO77_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC protein"
     gene            1937..2767
                     /locus_tag="VVO77_001365"
     CDS             1937..2767
                     /locus_tag="VVO77_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU5693373.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            2921..3775
                     /locus_tag="VVO77_001366"
     CDS             2921..3775
                     /locus_tag="VVO77_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEU5693374.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIGDTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEETS
                     DGLDQPVW"
     gene            3875..5248
                     /locus_tag="VVO77_001367"
     CDS             3875..5248
                     /locus_tag="VVO77_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEU5693375.1"
                     /translation="MVFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAYFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQRHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEDRMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            5241..6302
                     /locus_tag="VVO77_001368"
     CDS             5241..6302
                     /locus_tag="VVO77_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEU5693376.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEESSVLEIFSDPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGSSTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGGQ"
     gene            6304..6996
                     /locus_tag="VVO77_001369"
     CDS             6304..6996
                     /locus_tag="VVO77_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5693377.1"
                     /translation="MESLIQTYLPNVYKMGWSGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIVIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(7026..7595)
                     /locus_tag="VVO77_001370"
     CDS             complement(7026..7595)
                     /locus_tag="VVO77_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEU5693378.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADGVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            7730..8344
                     /locus_tag="VVO77_001371"
     CDS             7730..8344
                     /locus_tag="VVO77_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEU5693379.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFISSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            8346..9992
                     /locus_tag="VVO77_001372"
     CDS             8346..9992
                     /locus_tag="VVO77_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU5693380.1"
                     /translation="MKHFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKVSPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVDSIQAIAQGQEGLRIDTLEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQKYFEHQASYSDQRQ
                     SIGIINVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            10004..11290
                     /locus_tag="VVO77_001373"
     CDS             10004..11290
                     /locus_tag="VVO77_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU5693381.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLSSFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            11351..11884
                     /locus_tag="VVO77_001374"
     CDS             11351..11884
                     /locus_tag="VVO77_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5693382.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELA"
     gene            11962..12432
                     /gene="nrdI"
                     /locus_tag="VVO77_001375"
     CDS             11962..12432
                     /gene="nrdI"
                     /locus_tag="VVO77_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEU5693383.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(12725..13987)
                     /locus_tag="VVO77_001376"
     CDS             complement(12725..13987)
                     /locus_tag="VVO77_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEU5693384.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIIIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(14297..14755)
                     /locus_tag="VVO77_001377"
     CDS             complement(14297..14755)
                     /locus_tag="VVO77_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEU5693385.1"
                     /translation="MKKQVFHDAATGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWATIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(14752..15192)
                     /locus_tag="VVO77_001378"
     CDS             complement(14752..15192)
                     /locus_tag="VVO77_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU5693386.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            15625..16491
                     /locus_tag="VVO77_001379"
     CDS             15625..16491
                     /locus_tag="VVO77_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU5693387.1"
                     /translation="MGTLLATRLKNRRKELKMSQRELAEGICKQGQISRLESGEFTPG
                     ADFLNALAKKLKVSMDYFFDEQVVEKVEELSEFKKLAQTFITNRNYESLKYIYELENV
                     KAHRLSLADKIYMEWIKSLIDFYFYGQKEDAIVRLEGVLSQLSVSDLNYLQVSNTLFN
                     FYYDIGDLGRFNKIREKLEYQVNHLNLSTIEELELSIKFNYNVCRYLWLQKNIEEAIT
                     KITATIKQCKAYRTNYLLADLYLLMGNVSENFSSKSSVKEYFETAYFLYKLEENMSMT
                     LKVEHYIADITE"
     gene            16828..17385
                     /locus_tag="VVO77_001380"
     CDS             16828..17385
                     /locus_tag="VVO77_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase family
                     flavoprotein"
                     /protein_id="HEU5693388.1"
                     /translation="MDKKNLLVLVTGSVGASNVDTYLYYIKKFYNVKVILSENSKKFI
                     SKELISYFCDKVYDEIFVEEVVPHVFLPYESDLLLILPATANVIGKIANGIADDLVTA
                     TVLNFNKKIIFCPNMNSTMWDNHIVQRNVSILKELGHIFLFESKKTYEVGLRKAIDST
                     CSMLQPQSLVKELIKLENIVLEEGH"
     gene            17606..18712
                     /locus_tag="VVO77_001381"
     CDS             17606..18712
                     /locus_tag="VVO77_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HEU5693389.1"
                     /translation="MINKKIQQVVLESLQNFLNGNFISPCVVYDFGLLETVLDEFKNQ
                     IPVTFNYQLFYAVKANSNEKILEFLVDKIDGVDVASLSELDVAKKFFPPTQISVNGSA
                     FSYETLYNLIKKQYKVDINFLEHLQQFSPKESVGIRVTEPDELNNRMSRFGINICSDN
                     WTSNLQNPLITRLHFHFGEKDDKFIVKLDKILFKLQEINKLREVREINLGGGFMKLFM
                     ENRLKEFFLSLMEIYKKYDIDSTVTTIIEPGSAITSFSAYMITSPVNVSEVNEQQVIT
                     LDTSIYTNTLWFVPHIITTLNSSSKERYSTILYGNTCYEHDKYKMKVSLPRLTQNSSI
                     VFFPVGAYIKSNHSNLHRNDFMREVYLWTKNLTY"
     gene            18688..20079
                     /locus_tag="VVO77_001382"
     CDS             18688..20079
                     /locus_tag="VVO77_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693390.1"
                     /translation="MDKKLDILDKVKEYLGNKTTQILDNQYKEFLKLNDIRRAFGISE
                     KVLNNSFNFTSKEFNDLINNENYLFEYACRIREEWRKKCFNHSYRFLCSPIITDDFLN
                     TKTLRSSQIEYKYERYLSKSSIGDRAVDGFVSFNTLTANGMSAIKLCLEILNSIFFKK
                     KIDLLYSTGYYETRFLLNNLAKSGISCYEVSNCELDKDKFYNVFMMEPNRADLTLQKT
                     DFKIVEYFVKYKNNSIKVVILDISYQGSNFKLVEFLEKFKFANVIIFVVRSLIKLDQM
                     GLELTNGGIIEVFIPNHLRKLKNFIEEEFNKFRNSHGANLSLYEYCLLDNSLTLKNDW
                     NYSDLVMKFTSNFYADIKDLFMENSDIEIIHEEGVPFVFLDLIGEGKKEYEMFFQWLN
                     FFYKQLGITLYARNSFGFRNLTVEYFGIIGTERYIFKICPGVYKGLSYYLMKFLLKSF
                     SNEYLKTTDEVNR"
     gene            20076..21254
                     /locus_tag="VVO77_001383"
     CDS             20076..21254
                     /locus_tag="VVO77_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU5693391.1"
                     /translation="MKNLIKLLIIRLIVNLADSVFYIVALWHVSNNYSSSMFLGIFIA
                     VNYLPDLLLIFFGPVIDRVNPQKILIISILVQLAVAVIFLLLLNQISFWVIMSLVFIS
                     VMASSISYVIEDVLIPQVVEYDKIVFANSLFSISYKVLDSIFNSFASFLQVAVGFILL
                     VKIDIGIFLLALFILLLLKFRTSNANIENFSFKYYKREVLQGTKFILNNKLLFKTSIS
                     LTLINFFYSFQTVVVPIFSIRYFDGPIFYGIFLTIAGLGGILGNMLAPIVIKYLKSNQ
                     IVGVFLFLNGSSWLVAIVIKDYTLSLILFFVCFMSKGVFNIIFNSLYQQIPPHQLLGR
                     VNTTIDSIISFGMPIGSLVAGTLIDLNIELVLIAISIPYFLFSYIFYTDNGLKEFSIY
                     "
     gene            21679..21912
                     /locus_tag="VVO77_001384"
     CDS             21679..21912
                     /locus_tag="VVO77_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000623387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU5693392.1"
                     /translation="MISIDLGGTNIKITVLSNDGEIETLWSITTDTSEKGSQIISDII
                     SSIKNKLTERNIPDSDLLGIGMGSCSSYFPCKS"
     gene            22195..24144
                     /gene="mutL"
                     /locus_tag="VVO77_001385"
     CDS             22195..24144
                     /gene="mutL"
                     /locus_tag="VVO77_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEU5693393.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(24469..24936)
                     /locus_tag="VVO77_001386"
     CDS             complement(24469..24936)
                     /locus_tag="VVO77_001386"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEU5693394.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(24937..26142)
                     /locus_tag="VVO77_001387"
     CDS             complement(24937..26142)
                     /locus_tag="VVO77_001387"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEU5693395.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(26162..26236)
                     /locus_tag="VVO77_001388"
                     /pseudo
     CDS             complement(26162..26236)
                     /locus_tag="VVO77_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase subunit alpha"
BASE COUNT         8086 a         4507 c         5521 g         8137 t
ORIGIN      
        1 gtgttttgag ctgacttcat cagttctatc tgcaacctca aaacagtgtt ttgagcaacc
       61 tgcggctagt ttcctagttt gctctttgat tttcattgag tattattaag acaatatgag
      121 gagaaagatg aaagaaaaag gattttagga gggggcgcag gcagccatgc caacggctct
      181 tggctatgtc agtatcggcc tggcctgtgg gactatcggt gcgccctatg tgacacctgt
      241 tgagatgggc ttgatgagtc tctttgttta tgctgggaat gcccagtttg ccatgttggc
      301 actgattgtg gttcaagctc ctgtggcagc tattgctatg acggtttttc taatcaactt
      361 gcgtctcttt ttgttgagtt tacacgcatc gacttatttc cgtcatacca gtctttggta
      421 caatatcggt atgtctagta tcttgacaga tgagacctat ggcgttttga tgggtgaatt
      481 ggcccataca gacaaggtaa atcctatgtg gatgcacgga aacaatctta acagctatgt
      541 ggcttggttt gtggggacag tagtcggaac ggctctgggt ggcctgctac caaatccaga
      601 aatctttgcc ttgattcttt caagcgtagt gacaggtaag gttgggagcc ttcctcaaat
      661 taaatggcta gacttcttag ccgtctttcc aacagcttgg gtagcctttc gctaccgcaa
      721 tctagtcgga acagttctct ttggagtagt cttgattgcc gtcttgcgtt tggtctttta
      781 aatcagccat aaagaaaacc tatcacagat atatatatca tataatggtg taaatgattt
      841 ttttctgtta agactataag gtattctatt ttggaggaaa tgacatgaaa aaaatcgtta
      901 aatactcatc tcttgctgcc ctagggcttg ttgctgcagg tgtgctagca gcttgctcag
      961 gtggtgctaa gaaagaagga caagcagcta gcaagaaaga aattattgtt gcaactaatt
     1021 cttcaccaaa accattcaac tatgaagaaa atggcgaatt gactggttac gagattgaag
     1081 tcgttcgcgc tatctttaaa gactctgaca agtatgatgt caagtttgag aagacagagt
     1141 ggtcaggtgt ctttgcgggt cttgacgctg accgttacca aatggctgtt aacaacatca
     1201 gctacactaa agaacgtgcg gagaaatacc tttatgcagc cccaactgtt aaagacccta
     1261 acgttcttgt agtcaagaaa gacgattcta gcatcaaatc gcttgatgat gttggtggaa
     1321 aatcaacaga agttgttcaa ggaacaacat ctgctaaaca gttagaagac tacaacaaac
     1381 aacactcaga taatccaact atccttaact atactaaagc aaacttacaa caaatcatgg
     1441 gccacttgag cgatggtcag tttgactaca agatttttga taaaatcact gttgaaacag
     1501 tcatcaagaa ccaaggtttg gacaacttga aagtcatcga acttccaagc gaccaacaac
     1561 cttacgttta cccacttctt gctaaaggtc aagatgagtt gaaaacattt gtagacaaac
     1621 gtatccaaga actctacaaa gacggaactc ttgaaaaatt gtctaaacaa ttcttcggag
     1681 acacttacct accggcagaa gctgatatta aataatttct tgaaatcatc cattctgagt
     1741 aagatgggtg atttttcagt tcgctaccgc aatctagtcg gaacagttct ctttggagtg
     1801 gtcttgattg ccatcttgcg tttggtcttt taaattaccc ataaaaaaaa cttatcacag
     1861 agatagatat catataatgg cgtaaatgct ctttttctgt taagattata aggtattcta
     1921 ttttggagga aatgacatga aaaaaatcgt taaatactca tctcttgctg ccctaggact
     1981 tgttgctgca ggtgtgcttg cggcttgctc agggggtgct aagaaagaag gagaagcagc
     2041 tagcaagaaa gaaatcatcg ttgcaaccaa tggatcacca aggccattta tctatgaaga
     2101 aaatggcgaa ttgactggtt acgagattga agtcgttcgc gctatcttta aagattctga
     2161 caaatatgat gtcaagtttg aaaagacaga atggtcaggt gtctttgctg gtcttgacgc
     2221 tgaccgttac aatatggctg tcaacaatct tagctacact aaagaacgtg cggagaaata
     2281 cctctatgcc gcaccaattg cccaaaatcc taatgtcctt gtcgtgaaga aagatgactc
     2341 tagtatcaag tctctcgatg atatcggtgg aaaatcgacg gaagtcgttc aagccactac
     2401 atcagctaag cagttagaag catacaatgc tgaacacacg gacaacccaa ctatccttaa
     2461 ctatactaag gcagacttcc aacaaatcat ggtacgtttg agcgatggac aatttgacta
     2521 taagattttt gataaaatcg gtgttgaaac agtgatcaag aaccaaggtt tggacaactt
     2581 gaaagttatc gaacttccaa gcgaccaaca accgtacgtt tacccacttc ttgctcaagg
     2641 tcaagatgag ttgaaatcat ttgtagacaa acgcatcaaa gaactttata aagatggaac
     2701 tcttgaaaaa ttgtctaaac aattcttcgg agacacttat ctaccggcag aagctgatat
     2761 taaataattt cttgaaatca tccattctga gtaaggtggg tggtttctca gtttttaggg
     2821 atatagtttt aaactatata tctgactatc taataacaat ttgtgaaatc aaacaaattg
     2881 tgagatacta gtacggtatt atttttaagg agaaagaatc atgaaaatca aaaaatggct
     2941 tggcctagca gcccttgcta cagtcgcagg tttggctctt gcagcttgcg gaaactcaga
     3001 aaagaaagca gacaatgcaa caactatcaa aatcgcaact gttaaccgta gcggttctga
     3061 agaaaaacgt tgggacaaaa tccaagaatt ggttaaaaaa gacgggatta ccttggaatt
     3121 tacagagttc acagactatt cacaaccaaa caaagcaact gctgatgggg aagtagattt
     3181 gaacgctttc caacactata acttcttgaa caactggaac aaagaaaacg gaaaagacct
     3241 tgtagcgatt ggagatactt acatctctcc aatccgcctt tactcaggtt tgaatggaag
     3301 tgccaacaag tacactaaag tagaagacat cccagcaaac ggagaaatcg ctgtaccgaa
     3361 tgacgctaca aacgaaagcc gtgcgcttta cttgcttcaa tcagctggct tgattaaatt
     3421 ggatgtttct ggaactgctc ttgcaacagt tgccaacatc aaagaaaatc caaagaactt
     3481 gaaaatcact gaattggacg ctagccaaac agctcgttca ttgtcatcag ttgacgctgc
     3541 cgttgtaaac aataccttcg ttacagaagc aaaattggac tacaagaaag cacttttcaa
     3601 agaacaagct gatgaaaact caaaacaatg gtacaacatc attgttgcga aaaaagattg
     3661 ggaaacatca cctaaggctg atgctatcaa gaaagtaatc gcagcttacc acacagatga
     3721 cgtgaaaaaa gttatcgaag aaacatcaga cggtttggat caaccagttt ggtaataaga
     3781 aacagggagg tgggagagag aattccacct cttgcttttg tatagagcac ggagtgtaaa
     3841 gaagactatt cgttcataga aaggtagaga gaatatggtt tttcctagcg aacaagaaca
     3901 gattgaaaaa tttgaaaagg atcatgtagc ccagcattat tttgaggttt tgcgtacctt
     3961 gatttctaag aaatcagtct ttgcccagca ggttggactc aaggaagtcg caaattatct
     4021 gggtgagatt ttcaagcgtg ttggagctga agtggagatt gatgagagct atacagcgcc
     4081 ctttgtcatg gcatatttca agagttcgcg tccagatgcc aagaccttga ttttctataa
     4141 ccactatgac actgtgccag cggatgggga tcaggtctgg acagaggatc cttttacgct
     4201 ttcggtccgc aatggcttca tgtatgggcg tggggttgat gacgacaagg gtcatatcac
     4261 agctcgcttg agtgctttga gaaaatatat gcagcgccat gatgatttac ctgtcaatat
     4321 cagctttatc atggagggag cggaggaatc ggcttcaaca gacctagata agtatttgga
     4381 aaagcatgca gacaaactcc gtggggcgga tttgttggtc tgggaacaag ggaccaaaaa
     4441 tgccttggaa caactggaaa tttctggtgg caataagggg attgtgacct ttgatgccaa
     4501 ggtaaaaagc gctgatgtgg atatccactc gagttatggt ggcgttgtgg aatcagctcc
     4561 ttggtatctc ctccaagcct tacagtctct tcgtgctgcg gatggccgta tcttggttga
     4621 aggcttgtac gaagaagtac aagagcccaa tgaacgagaa atggccttgc tagaaactta
     4681 tggtcaacga aacccagagg aagttagtcg gatttatgga ttggagttgc ctctcttaca
     4741 ggaggatcgg atggcctttc taaaacgttt ctttttcgag ccagcgctta atatcgaagg
     4801 aatccagtct ggttatcaag gtcagggtgt taagactatt ttacctgcag aagccagtgc
     4861 caagctagag gttcgtctgg ttccgggcct agaaccgcat gatgttctgg aaaaaattcg
     4921 gaaacagcta gacaaaaatg gctttgataa ggtagaatta tactatacct tgggagagat
     4981 gagctatcga agcgatatga gcgcaccagc cattctcaat gtgatcgagt tggccaagaa
     5041 attctatcca cagggcgttt cagtcttgcc gacgacagcg gggacaggac ctatgcatac
     5101 ggtctttgat gccctagagg taccaatggt tgcattcggt ctaggaaatg ccaatagccg
     5161 agaccacggt ggagatgaaa atgtgcgaat cgctgattat tacacccata tcgaattagt
     5221 agaggagctg attagaagct atgagtagag atattatcaa gttagatcag atcgatgtga
     5281 cttttcatca aaagaagaga accattacag cggttaagga tgtgaccatt cacatccaag
     5341 aaggggatat ctacggaatc gttggatatt ctggagcagg gaaatcaacc cttgtacggg
     5401 tgattaacct cttgcaaaaa ccatctgcag ggaaaattac cattgacgac gatgtgattt
     5461 ttgatggtaa ggtcaccttg acggcagagc agttgcgtcg taaacgtcaa gatatcggga
     5521 tgattttcca gcattttaac ctgatgagcc aaaagacagc agaggagaat gtagcctttg
     5581 cccttaaaca ctctggactc agcaaggaag aaaagaaggc taaagtagct aagttgttgg
     5641 acttggttgg tttggcagat cgtgctgaaa actacccttc acaactatct ggagggcaaa
     5701 aacagcgtgt ggcaattgcg cgtgccttgg ccaatgatcc aaaaatcttg atttcagacg
     5761 agtcaacttc tgcccttgac cctaagacaa ccaagcagat tttggccttg ttgcaagatt
     5821 tgaaccaaaa attaggcttg actgttgtcc tgattacgca tgaaatgcag attgtcaaag
     5881 acattgccaa ccgtgttgca gttatgcagg atgggcattt gattgaagag agtagtgtgc
     5941 ttgaaatctt ctcagaccct aaacaacctt tgactcaaga ctttatctca acagctacag
     6001 gtattgacga agccatggtc aaaatcgaga agcaagaaat cgtggaacac ttgtctgaaa
     6061 acagtctctt ggtgcaactc aagtacgctg gatcttcaac agacgagcca cttttgaatg
     6121 aattgtacaa gcattatcaa gtaatggcta atattctcta tgggaatatc gaaatcctcg
     6181 atggtactcc tgttggagaa ttggtggtgg tcttgtcagg tgaaaaagca gcgctggcag
     6241 gtgctcaaga agccattcgt caagcaggcg tacagttaaa agtattgaag ggaggacagt
     6301 aagatggaat cattgattca aacctattta ccaaatgtct ataagatggg ttggtctggt
     6361 caggcaggct ggggaacagc tatctaccta accctctata tgacagttct ttccttcatt
     6421 atcggaggct tcttggggct agtggcaggt ctctttctcg tcttgacagc gccaggtggt
     6481 gtcttggaga ataaagtcgt attctggatt ttagacaaaa ttacctcaat ttttcgtgcg
     6541 gttcccttta tcatcctctt ggcaatcttg tcaccacttt ctcacttgat tgttaaaaca
     6601 agtatcgggc caaatgcagc ccttgtccca ctttcttttg cagtctttgc cttctttgcc
     6661 cgtcaggtgc aggttgtctt ggctgaattg gatggcggtg tcattgaggc ggctcaagcg
     6721 agcggagcga ctttctggga catcgtgggt gtttacctat cagaaggtct tccagatttg
     6781 atccgtgtga cgactgtgac cttgatttcc cttgttgggg aaacagctat ggccggtgcg
     6841 gttggagctg gtggtatcgg taacgtagcc atcgcttatg gatttaaccg ctacaatcac
     6901 gatgtgacca tcttggcaac catcgttatc attttgatta tctttgcaat ccaattctta
     6961 ggagatttct tgactaagaa attgagccat aaataaaaaa gagccgtgtg gctcttttta
     7021 actgatcaga ttttctgggc aaatttttta ctcaaggctt gtccaatcaa ggcacccact
     7081 agggctccga tgacaatact tgcgataaat agaaggacag ttccagggtt tggagcgacc
     7141 atgatgcggt cgatatattc ttgggatttt cctcttgcca gaagagtagc catataggct
     7201 ttgggcgcaa tccacataag caagattggt cctgttgtac taaaggcgaa aataatgaaa
     7261 gaaaggaagt tctttgtttt gtccttgtat tttcctaaat gagctactcc atctgctagg
     7321 aggccacaga taattccagg aaggaaggaa ccagcaccgt gtttagttcc caagaaaaag
     7381 agggcaatga caaggccgat agtggtaatg gctccaaagc gcggaacttt tgcgactagg
     7441 atcatataga cgctaccgcc gacaagggca gtaaaggcag gcgcataaaa catgtttcca
     7501 gtttggtcaa agagattgcc caaaaggaca ccaatcccca tgcagaggaa gtaaagaact
     7561 gcaaaaagca gtgtagttaa gatagatttc ttcatgaatt gtctcctgat aattttttca
     7621 caattctcat tttaccatgg tttggtggga ttgtaaatgg atactagaag tttttgaaaa
     7681 cgcttgaaat atgatataat ggtttcatag ttatttttag gggaatatca tgggtagatt
     7741 tttagacttt gtctttaatc gtttcttttt agggatgatt gcgacagcct tcttttggct
     7801 attaacttta gcaggaggga ttatccttgg tctagcgccg gctagtgcca ccttgatgag
     7861 cttatatgca gaacatggtt atagctttcg ggaatacagt ttgaaggagg cttggtctct
     7921 ttacaagcaa aattttatct caagcaacct gattttctat agctttttag gtgtgggtct
     7981 agttttgacc tatggtttgt atctcttggt gcaattgcct catcagacca ttgttcattt
     8041 gattgcgacc cttttgaatg tcctagtagt tgccctgatc tttttggctt atacagtatc
     8101 tttaaaatta caagtttatt ttgccttgtc ctatcgaaat agtctcaaat tatccttgat
     8161 tggcatcttt atgagtctag cagctgtggc taaggttctc cttgggactg tgctacttgt
     8221 agcaattggt tactatatgc ctgccctgct attttttgta ggaattggga tgtggcattt
     8281 ctttatcagt gatatgttgg aacctgtcta tgaaatcatc catgaaaaat tggcgacaaa
     8341 atagaatgaa gcacttttgg ctacatacgc ttctaagaac ctatagttca gtgatgatca
     8401 ttatcattgc gagttttgca atcttactct cttacgctga ctgggattca cgtgaaaagg
     8461 aagcccagag agtagcccag cgtgtaactg ctagaacagt gagtgaaatt gaatattacc
     8521 atagagagtc aacccagata gctcaggctt tagttgaaaa ccaagctcgt attgagggaa
     8581 tctataaata ctttagcctt agcatgccag actattttta ctggcaatta gagcggaaag
     8641 tttcgcctta tatatcagtc tctctgtatg aaaatgttga tgacctctat gttcgaaatg
     8701 attttgtaac tggggtggcc attgcttttc aagattacaa ggaagtctat gtttctacta
     8761 aagacaaacg tagtggagaa aaaatcaggg ctgaggattt caaaccagca ggaaatagtt
     8821 ttgccattcc agtgtcagat ccagtgtcag atcaagactt aggagtgatt tacatctcct
     8881 tggatcctgc tgttttatac catgccattg ataatactag aggtcatact ccgatggcag
     8941 taacagtgac ctcacctttt gatacggaga tttttcatat tggtgagaca gttgataagg
     9001 agagtgaaaa ttggctagtt ggcttaactt ctcatggtta tcaggttcag gtggcagttc
     9061 ccaaaaactt tgttttacaa ggaacggtga ccagctctgc tttgattgtg ggcttgagcc
     9121 ttctctttat tgtcattctt tatctgactt tgaggcagac ctttgctaat tatcaaaagc
     9181 aggtagtgga tttggtggat tccatccaag ctattgccca aggacaagaa ggtcttcgca
     9241 ttgatacgct tgaaaaggat caggaattgc tcctaatcgc ggagacgacc aatgatatgt
     9301 tggatcgatt ggaaaagaat atccatgata tttaccagtt agagcttagt caaaaagatg
     9361 ccaatatgcg agccttgcag gcgcaaatca atcctcattt tatgtataat acgctggagt
     9421 tcttgcgcat gtatgcagtt atgcagagtc aagatgagtt ggcagatatc atttatgaat
     9481 tcagtagtct cttgcgtaac aatatttccg acgaaagaga gaccctcctc aaacaggaat
     9541 tagaattttg ccgtaaatac agctatctct gcatggttcg ctatcccaag tccattgcct
     9601 atggtttcaa gatagatcca gagttagaga atatgaagat tcccaagttt accttgcaac
     9661 cgctggtaga aaactatttc gcgcatggtg ttgaccacag gcggacagat aatgtgatta
     9721 gcatcaaggc tcttaaacag gatggttttg tggaaatttt ggtggtcgat aatggtagag
     9781 gaatgtcggc tgaaaagttg gcaaatatcc gagaaaaatt aagtcagaaa tattttgaac
     9841 accaagccag ctacagtgat caaaggcagt ctatcggaat tatcaatgta cacgagcgtt
     9901 ttgtgctcta ttttggagac cgctatgcca ttacgataga gtctgcagag caagccggtg
     9961 ttcagtatcg tattacaatt caagatgagt agaaagggag aaaatgtata aagtattatt
    10021 agtagatgat gagtacatgg tgacagaagg tctgaagcgt ttgattccct ttgataagtg
    10081 ggatatggag gtcgtcgcaa cagccagtca tgccgatgaa gctctagaat atgttcagga
    10141 aaatcctgtc gatgtcatca tttccgatgt caatatgcca gacaaaacag ggcttgatat
    10201 gattcgggag atgaaagaga tcttaccaga tgctgcctat atcctgctct caggttatca
    10261 ggagtttgat tatgtaaaaa gagcaatgaa ccttagtgtg gtggactatt tggtcaagcc
    10321 tgttgataag gtagagctgg gaaatctgct ggagaagatt gcaggtcagc tcggcgagag
    10381 agggaagaaa agtcagactc ttagtcaaga attagacgag gctggatttg ttagttattt
    10441 aggggataag gagaattggt ggataggtct atccaaggaa aaacaaggtt ccttcaccat
    10501 tccctactat gtcttgggcc aagactggca gattttcatt tctgaccaac ccctagatgg
    10561 tttagtcgtt acaccttttg aagctcctta tcaagaacac tttgaacgct ggaagctgaa
    10621 tgctgagaaa accctctttt acggttctgt aaatttgcag cagtctgaga gtctctttgc
    10681 ctattacgaa ccgatttata gggttatcat tcagggaaat ctcaatcaaa tcgtagaaga
    10741 gttaaatctc ttggagaagg tagttcttga aaatacgccg cgtgttccga ttactaaaca
    10801 gctttttatt cagtttgtca tggatgtttt ccatttattt gaacatctca aagctgatga
    10861 cctgacagac atcgtcaaaa ccattcatgc tattcaatcc ttcgatgaat tggttcctta
    10921 tatcaaggaa actctgagca gctttttcgg tcaataccgt atgaatgaaa atgtggtcag
    10981 tgtgctggaa gtcattggtc gtgattacca aaaagagctt tccctcaagg atatcagtaa
    11041 ggctctcttt atcaatcctg tctatctagg gcagttgatt aagcgtgaaa ccgattcgac
    11101 ttttgcagag ttactaaaca aacaacgtat taaggctgcc caacaacttt tgctttcaac
    11161 tagtgacagc atcgaagata tttgttatgc tgttggttac agtaaccttg gatatttcta
    11221 taaagttttc cgaaaattgt gcggaaaatc gccaaaagcc taccgaaaac aggtagaaac
    11281 tatactataa gatttgtatt cctttacaaa atgtgctata atataaatat tattattagg
    11341 aggttctatc atgaaaaaga aaccaattta tctatgggtc ttgctaatct tgtctgccct
    11401 tatttcagtt ccgtctctgt ttggaattgt gagtcccttg cctagtaaag aagcccttcg
    11461 tgctgctcag aaacaagttg caggggtcaa tgctcagcaa ttagaagacc agcttaatta
    11521 tacctataga gtagcagaag catctcattc tatttttaat gttgctttga ttgtgctatc
    11581 tactatttta gtggtcgtag cgattgtctt ccttgttcgt aaaaatttgc aatatgcaaa
    11641 ctatacttac gttggctatg ttttgttagc tattattggt tcgatttatg gctatgttgg
    11701 tttacaagac gctgtgcagt tggttcaaga tgagagcatg cgtttgacag tgagtattgg
    11761 ttcaaaagct gttagcattt tctatatcgt catcaatgtt ctcttcctag cccttgtctt
    11821 ctataagatg tggcgacaac agaaagcctt ggcagaagaa gaggaaacag aagagcttgc
    11881 ctaagtattg acaaaaaaga actatcaaga tacaatcttg gtagttgttt tttgattata
    11941 gataaaatca tggaggtaca tatgaagaca atttctttag tttatattag tttgagtggc
    12001 aacactgaaa gttttgtgac gcgcttgaaa gactatctct tgtcccagta caaagggatt
    12061 gaggttcaaa agattcatat caaggatttg gtcaaggaag gcaaaaattt ctacgaaatg
    12121 gaccatccct atgttgcttt tttgccgacc tatctcgaag gtgggaatgg cgtggataac
    12181 ggagatgttg agattttgac gacaccggtg ggagatttta ttgcctatgg taacaatgct
    12241 agtaagtgtt ttggtgtggt tgggtcagga aatcgtaact ttaataacca atactgccta
    12301 acagccaagc aatacagtca acgctttggc tttcctgtat tggctgactt tgaaatgcga
    12361 ggcatgctgg aagatatcaa acatgtcgca gctattatcg cagatttgta tgagttggaa
    12421 aaggagaatt aatactcaat gaaaatcaaa gagcaaacta ggaagctagt cgcaggttgc
    12481 tcaaagcaca gctttgaggt tgcagataga gctgacgtgg tttgaagaga ttctcgaata
    12541 gtataaagtt cttataagag gtggttgaag ttgttcaact gttttttgag tataaacagt
    12601 ctttaagaac gtaaaaaagc ataagttcag gtcttcaaaa ccttgttctt atgcttttta
    12661 tcatagaaat atttgctgaa ttttctcttg aaatgaaacc ttatcttcat ctcgcgcttg
    12721 tcccttaccc tgcttttccg attgcgagtg cgtagataaa gaagatggcg aagccaaaga
    12781 ggaaaatcaa tcccgcaatg gcaaggtgtt tgagccaaga aggaagattt ttgttttcac
    12841 gtgttaccaa ggcgtaattc aaaagagcaa agaaaggtgt tgtcaggaaa gagccaatca
    12901 tggcaaagcg gagcatggtt gaaacctgac cagcgaagaa cttgataatg atgataccga
    12961 tgatagcagt gatggtcatc cagatgttca aagatttacg attatcctct ttttgactga
    13021 ttagcagtcg gagagattcc tgattaacgc gagaatagcc atcgataaca gttataactg
    13081 ttccaaagat acagaggaag gcaataaagg taatcaagta acgggaccat tcgccaagaa
    13141 cagaggcata catgcccacg aattgagaga tgtatttggc tgaagcagct tcaaccgcct
    13201 gccctgtagg atactgaatc agtgctccca gtgccacaaa gaagacggct aggatagctg
    13261 ttccaatata accagtgtta aagtcaaaca gagcgtcttc tgtgttaaag ttgacggtct
    13321 ttctcttttc agctgaccaa agtgaattga tggctgaaat ttcaatagga gccggcatcc
    13381 atcctaggag ggagacgatg aagggcagag ctgccatttg ccaaggtgtc ttctcgacaa
    13441 aatcagaact gtattctgga tgcttgaccg ccgcaatgat aactgcaaga acagtcgcaa
    13501 tggttaaggc agacataatc catttgacca tgccgtctaa aagtttgtag cctccaaaga
    13561 gtagcatagc ccaaatgatt gcaacgagaa tgagggacca ctgagtaatg ctaagtccaa
    13621 tcattgggaa ggcactggcg atgatagctg agcacagaat ggcaacacca gccgtgttga
    13681 ccatagccga aaagacattg aggataaaga aaatccagag atagagtttt cctttttcgg
    13741 cataaccttc aaccaaagtc tttccagtat cagctgtgta ttcagcacca aaacggaaaa
    13801 atggatattt aaagacattg gctaagatga ccaagagaag tagagaccaa ccgtaagaac
    13861 cgccagcttg agttgaggat acaatgtggg aacctccaac agcggcagtt gccattagga
    13921 ttccaggtcc cattgctttt agcttgcttg cccaggttga ttgatttaag gaaatagctt
    13981 gcgacatgat aaatactcct ttttgaattt tcagaataat ctgtatatgt aatctatatt
    14041 ctacaaaaaa ttttggaaaa atgcaagagt attttgaaaa aagatagaaa atttacaaag
    14101 aaaatctgaa ataactgtta tgatatagag gattgaaact agaatagtac acctctgctt
    14161 ctaaaacatt gttagaaatc gatttgactg tcctgatcga tttatcctgt tcttatttca
    14221 tttcactata gtaaggtgca gcaggataaa gaaaatccga gaagtttctt tctcggattt
    14281 gcttattatg aggttcctat tttctatgct ccaagagttg attgatgtga tctacttttt
    14341 tagcctctct tttatagaga atagcccaga tgatgagata gacaatcgca aactcgataa
    14401 tgagctggag gtagaaaatc cagtggaaag ggaaccaacc agcaagagtt gctagtggga
    14461 caaagccagc cagcataagg aagaaatgag tcagagtggc acgaagcatg ctccagtcac
    14521 ggctaaataa gcggttgcca aagttgaaga gcataccgat ggttgcccat ataagtgtgc
    14581 agtagagcaa gaccagggca ccgtgaacct gatgctgatc catcacttgg ccgatgagag
    14641 agtagggatt tagtggtgcg taggtatttg gtgcataaat gagtgaaaag aggatagaga
    14701 ggatgaggcc gataagaaca ccggtagctg catcgtgaaa tacttgtttt ttcatagttc
    14761 taatttctcc ttgatggttt ttagataacg gcgtgaagag taggtgaagc tttcgttttt
    14821 caagaaaatt tctaccagac cgtttggcgt gagcttgagg tgagagatgg aatcgatatt
    14881 gatgatttct gattgggaaa tttggataaa attggttggc aagagtttaa gaacctgata
    14941 gagtcgcaaa tcaatgctgt aggtctgact cgcggtttct gctagaacct tccgattctc
    15001 gatatagaag cgctgaatct tgccaatctc aactagatag acctgatcat cgatttttcc
    15061 tttgattttt tctctttggt ccagattttc tgcgaactcg atgactttct ggactttttc
    15121 ggtttcttga ggtgcttgga caatcagctt ttcctcctcg taagtctcac taatctgtag
    15181 ttctactttc atagttttct ctccttttca gttatacaag gttgtgatca cttcctgtat
    15241 atccttatta aacactattt tatagcccat ggcaaggaac cttgtctatg tggagggatt
    15301 gggctcctat gtggtggagc ttttctgttc tttctgaaat atggtataat agcactaatc
    15361 aatttctagg aaaatagata cggaaagggg ctgaaagaac taggggaaca gttggaatta
    15421 gaaagtgata ggtatgaaaa gtggcgttga agctgaataa gtttataaag cgtttgaatg
    15481 aagaaatgga aagtaaataa gttgacgatg aattacaaaa tagattttat ctacaatttg
    15541 tatctttcaa atcattgatt tgaattttag atttaatcat gttacaatta aaactgaaat
    15601 caaatagaag aggaaaatgc aaacgtgggc acactattag caacaagatt aaaaaataga
    15661 cggaaagaat taaaaatgtc tcagcgagaa ctagctgaag gtatctgtaa acaggggcaa
    15721 atcagtcgat tagagagcgg agagtttacc cctggagcgg atttcctgaa tgcccttgct
    15781 aagaagttaa aagtcagtat ggattatttt tttgatgagc aggttgtaga gaaagttgag
    15841 gagttatcag aatttaagaa attagcacag acatttatta caaatcgcaa ttatgagtct
    15901 ttgaaatata tatatgaatt ggagaatgta aaagctcacc gcctatcttt agcagataaa
    15961 atctacatgg aatggataaa atctctgata gatttttatt tttacggaca gaaagaagat
    16021 gcgattgtac gattagaggg ggtattatca cagttaagtg tatctgattt gaactatctc
    16081 caagtttcaa acaccctatt caatttttat tatgatattg gagatttagg tcgtttcaat
    16141 aaaattcgtg aaaaactaga gtatcaagta aatcacctca atttgagtac aatcgaagag
    16201 ttagaactat ctattaagtt taactacaac gtttgtcgtt atctatggtt acagaaaaat
    16261 attgaagaag ctattactaa aattacagct actataaaac aatgtaaggc ttacagaacg
    16321 aattatcttt tggctgattt gtacttattg atgggaaatg taagtgaaaa tttttcttct
    16381 aaaagttcgg tgaaagaata ttttgagacg gcatattttc tatacaaact tgaggagaac
    16441 atgtcaatga ctctgaaagt tgagcattac attgcagata taacagaata atgaatacgg
    16501 tgttcaagtg agcatcgttt ttcaaaccta gttcagatac aaaaaagtat caaacaaaaa
    16561 aaaataaaaa aacattataa aaacaattga caagctaatt ttgaagtgat aaattaaatg
    16621 caagaaaaca aaaggagagg tatatgagaa gtttgtttaa gaaaatagtt gctgtattag
    16681 ttattggctt aattctgtta ggaattgcga gaacacctca agttcataag atggctagag
    16741 ggattgatcc tggtcctgcg aattttattt agaaatcaat ttctactaat tgagtactaa
    16801 ttgagtatta atgggtaaaa agattgtatg gataagaaaa atttacttgt attggttact
    16861 ggttcggtag gtgccagtaa tgtagataca tacttatatt atataaaaaa attctataat
    16921 gttaaagtga tactttctga aaattctaaa aaatttataa gtaaggaatt aattagttat
    16981 ttttgtgata aagtttatga tgaaatattt gttgaagagg tagttccgca cgtttttctg
    17041 ccatatgaat ctgacttact tcttatttta ccagctacgg caaatgtgat tggcaaaatt
    17101 gctaatggta ttgctgatga tttagttaca gcaactgttt taaactttaa taaaaaaata
    17161 attttttgtc ccaatatgaa ctctactatg tgggacaatc acatagttca aagaaatgta
    17221 tcaattctaa aggagttggg acatatattt ttatttgagt ctaaaaaaac atatgaggta
    17281 ggattgcgta aagcaataga ttcaacatgt tcaatgttac aaccacagtc gttagtaaaa
    17341 gaacttatca aattagaaaa tattgtcctt gaagagggac attaaaaact actgagaata
    17401 ttaaggaggg gaaaaaatgg aaaattcatc aatcgatgta gatatgctgt tggaagaatt
    17461 gacacaagaa gcaatggtcg ttgttgctgt tgataaggac tgttaattta aacttatggc
    17521 aatatatgaa aggttactgg atgttttaaa ttatgcaggc agtagccttt tattatatac
    17581 aaatggataa agtaaggata atacaatgat taataaaaaa atacaacaag ttgttttgga
    17641 atcattacag aattttttga atgggaactt catttcgcct tgtgtagtct atgattttgg
    17701 cttgctggaa actgtacttg atgaatttaa aaatcaaatt cctgtaacat tcaattacca
    17761 acttttttat gccgttaaag caaattcaaa tgagaagata cttgaattct tagtagataa
    17821 aattgatgga gttgatgtgg cgtcattatc tgaattagat gtggctaaaa aatttttccc
    17881 accaactcaa atttctgtta atggttccgc attttcttat gaaactttat ataatctgat
    17941 taaaaaacaa tataaagttg atattaactt tttggaacat cttcaacaat tttccccaaa
    18001 agaatctgtt ggaataagag taacggagcc agatgaactt aataatcgta tgagtcgatt
    18061 tggaataaat atttgcagtg ataattggac tagtaattta caaaatcctt taattacacg
    18121 actgcatttt cattttggag aaaaagatga taaatttatt gttaagttag ataaaatatt
    18181 atttaagtta caagaaatta ataaacttag agaggttaga gaaataaatc ttggaggcgg
    18241 ttttatgaaa ttatttatgg aaaatcgttt gaaagaattt tttctatcac ttatggaaat
    18301 ctataaaaag tacgatattg atagtactgt gactacaata atagaaccag gtagtgcaat
    18361 tacttcattt tctgcctata tgattactag cccagttaat gttagtgagg tgaatgagca
    18421 gcaggttatc acgttagaca catcaatata caccaataca ttatggtttg ttccgcatat
    18481 tattacaacg ttaaattcaa gtagtaaaga gcgttatagt actattctct atggtaatac
    18541 ctgttatgaa catgacaagt ataaaatgaa agtttcgctt ccaaggttaa ctcaaaatag
    18601 cagtatagtg ttttttcctg taggagctta tataaaaagc aatcattcaa atttacatcg
    18661 taatgatttt atgcgggagg tatatttgtg gacaaaaaac ttgacatatt agataaagtt
    18721 aaggaatatt taggaaataa aactactcaa attctggata atcaatataa agaatttttg
    18781 aaacttaatg atataaggcg agcgtttggt atttcagaaa aagtattaaa caattctttt
    18841 aattttacga gtaaagaatt taatgattta attaataacg aaaattattt attcgaatat
    18901 gcatgtagaa ttagagagga atggagaaaa aaatgcttta atcattctta tcgttttcta
    18961 tgctcaccta taattacaga tgattttctt aacacgaaga cattgagaag tagccaaatt
    19021 gaatataaat atgagcgata tttatcgaaa agttcgatag gcgatagagc ggttgatggc
    19081 tttgtttcct tcaatacttt aacagctaat ggtatgtctg ctattaaact atgtcttgag
    19141 atattaaact ctattttctt caagaagaag attgatttat tatattcaac cggatattat
    19201 gaaacaagat ttttattaaa taatcttgct aaatcaggta ttagttgcta tgaggtaagt
    19261 aattgtgaat tggataaaga taaattttat aatgtattca tgatggaacc caatcgagcc
    19321 gatttaacat tacaaaaaac tgatttcaag atagtagaat attttgttaa gtataaaaat
    19381 aattcaataa aagtcgttat tttagatatt tcatatcaag gttctaattt taaattagta
    19441 gaatttttag agaaatttaa atttgcgaat gtaattattt ttgtggtacg atctttgata
    19501 aaattagatc aaatgggatt agaattgaca aatgggggaa taatagaagt gtttattcct
    19561 aatcatttga gaaagttgaa aaattttatt gaagaggaat tcaataaatt tagaaattct
    19621 cacggagcta atctaagcct ctatgaatac tgtttgcttg ataattcttt aactttaaaa
    19681 aatgattgga actattctga tttagttatg aaatttacga gtaattttta tgctgatata
    19741 aaagacttgt tcatggaaaa ttctgatatt gaaatcatcc atgaagaggg agtacctttt
    19801 gtatttttag atttaatagg tgaaggtaaa aaagaatatg aaatgttttt tcaatggtta
    19861 aacttctttt acaaacagct tggaatcaca ttgtatgcta gaaatagttt tgggtttcgg
    19921 aatctaacag tagagtattt tggaattatt gggacagaaa gatatatatt taagatttgt
    19981 ccaggtgttt ataaagggtt aagttattat ttgatgaaat ttttattaaa atctttttca
    20041 aatgaatatt taaaaactac tgatgaggtt aatagatgaa aaatttgata aagttgctaa
    20101 taattagatt gattgttaac ttagcagaca gtgtatttta tatagtagca ttgtggcacg
    20161 ttagcaataa ttattcttcg agcatgttct taggaatatt tattgcagta aattatctac
    20221 cggatttgtt actaatcttt tttggaccag ttattgacag agtaaatccg caaaaaattc
    20281 ttataatatc aattttggtt caattagcag tggctgtaat atttttatta ttattaaacc
    20341 aaatatcatt ttgggtgata atgagtctag tgtttatttc agtaatggct agctccataa
    20401 gttacgtgat agaagatgtg ttgattcctc aagtggtaga atatgataag attgtatttg
    20461 caaattctct ttttagtatt tcgtataaag tattagattc tatttttaat tcattcgcat
    20521 catttttaca ggtggcagta ggatttattt tattggttaa gatagatata ggcatatttt
    20581 tacttgctct atttatattg ttgttgttaa aatttagaac tagcaatgcg aatatagaaa
    20641 acttctcttt caaatattac aagagagaag tgttgcaagg tacaaagttt attttaaata
    20701 ataaattatt atttaaaacc agtatttctt taacgcttat aaactttttt tattcatttc
    20761 agacagtagt tgtaccgatt ttttctattc gatattttga tggtccgatt ttttatggta
    20821 tttttttaac tattgctggt ttgggtggta tattgggaaa tatgctagcg ccaatcgtaa
    20881 taaaatattt aaaatcgaat caaattgttg gtgtatttct ttttttgaac ggctcaagtt
    20941 ggttagtagc aattgttata aaagactata ctttatcact tattttattt ttcgtttgtt
    21001 ttatgtctaa aggagtcttc aatattattt ttaattcgtt gtaccaacaa atacctccac
    21061 atcaacttct tggtagggta aatactacca ttgattctat tatttctttt ggaatgccaa
    21121 ttggtagttt agttgcagga acgcttattg atttgaatat tgaattagtg ttaattgcta
    21181 ttagcatacc ttattttttg ttttcttata ttttttatac ggataatgga ttgaaagaat
    21241 ttagtatata ttagaaatgt ttatgttcat tcaaaagcat aatgactata actgaaaaag
    21301 aaaagtgata tctttaaggt tgttcttctt ggtggtgaga ttcgtgagac aacccaagct
    21361 tttgtcggaa agattaccaa tgctttgatg gataggatgt actttagcaa gatgttttta
    21421 gtggtaacgg tatcgtggat ggacgtgtaa taacctcttc tttcgaggag tattttacta
    21481 aaaaactagc cttggagcgt tccccagaaa cggacttact cattgactct tcaaagattt
    21541 ggggagaaga ttttgcttca tctgttcctt gaaaaaagtc acagcagtca tcacagacga
    21601 tagtactgaa caaaactatg aagagttaga aatttatacg caggtgattg tataaaggat
    21661 ctggaaatag ataagaagtt gattagtatt gacctaggtg gtacaaatat taagattact
    21721 gttctttcaa atgacggtga gattgaaact ttgtggagta ttacaacaga tacaagtgag
    21781 aaaggttctc aaattatatc ggacatcatc agttctatta aaaataaatt gaccgaacgg
    21841 aatattcctg atagcgacct tcttggaatc ggtatgggaa gttgctcatc atactttcct
    21901 tgtaaatcat aggggctata aactctccgt ctacttgtcc tgcaacaatt gaagtctgct
    21961 caaaacgccg tccgctaatc ttttcataga ctttctccct tttaggagcc tagctttcta
    22021 gtttgttctt tgatttttat tgagtatacc actattttac tccctctggc aagggacttt
    22081 gtctatgtgg agggattggg ctcctatgtg gtggagcttt tctgttcttt ctgaaatatg
    22141 gtataatagc actaatcaat ttctaggaaa atagatacag aaaggggctg aaagatgtct
    22201 catattattg aattgccaga gatgctggca aaccaaatcg cggctggaga ggtcattgaa
    22261 cgtcctgcca gtgtggtcaa agagttggta gaaaatgcca ttgacgcggg ctctagtcag
    22321 attatcattg agattgagga agctggtctc aagaaggttc aaatcacgga taacggtcat
    22381 ggaattgccc acgatgaggt ggagttggcc ctgcgtcgcc atgcgaccag taagataaaa
    22441 aatcaagcag atctctttcg gattcggacg cttggttttc gtggtgaagc cttgccttct
    22501 attgcgtctg ttagtgtctt gactctgtta acggcggtgg atggtgctag tcatggaacc
    22561 aagttagtcg cgcgtggggg tgaagttgag gaagtcatcc cagcgactag tcctgtggga
    22621 accaaggttt gtgtggagga tctctttttc aacacgcctg cccgtctcaa gtatatgaag
    22681 agccagcaag cggagttgtc tcatatcatt gatattgtca accgtctggg cttggcccat
    22741 cctgagattt cttttagctt gattagtgat ggcaaggaaa tgacgcggac agcagggact
    22801 ggtcaattgc gccaagcaat cgcagggatt tacggtttgg tcagtgccaa gaagatgatt
    22861 gaaattgaga actctgacct agatttcgaa atttcaggtt ttgtgtcctt gcctgagttg
    22921 actcgggcta accgcaatta tatcagcctc ttcatcaatg gccgttatat taagaacttc
    22981 ctgctcaatc gtgctatttt ggatggtttt ggaagcaagc ttatggttgg acgttttcca
    23041 ctggctgtca ttcacatcca tatcgaccct tatctagcgg atgtcaatgt gcatccaact
    23101 aagcaagagg tgcggatttc caaggaaaaa gaactgatga ctctggtttc agaagctatt
    23161 gcaaatagtc tcaaggaaca aaccttgatt ccagatgcct tggaaaatct tgccaaatcg
    23221 accgtgcgca atcgtgagaa ggtggagcaa actattctcc cactcaaaga aaatacgctc
    23281 tactatgaga aaactgagcc gtcaagacct agtcaaactg aagtagctga ttatcaggta
    23341 gaattgactg atgaagggca ggatttgacc ctgtttgcca aggaaacctt ggaccgattg
    23401 accaagccag caaaactgca ttttgcagag agaaagcctg ctaactacga ccagctagac
    23461 catccagagt tagatcttgc tagcatcgat aaggcttatg acaaactgga gcgagaagaa
    23521 gcatccagct tcccagagtt ggagtttttc ggacaaatgc acgggactta tctctttgcc
    23581 caagggcgag atggacttta catcatagat cagcacgctg ctcaggaacg ggtcaagtac
    23641 gaggagtacc gtgaaagcat tggcaatgtt gaccagagcc agcagcaact cctagtgccc
    23701 tatatctttg aatttcctgc ggatgatgcc ctgcgtctca aggaaagaat gcctctctta
    23761 gaggaagtgg gcgtctttct agcagagtac ggagaaaatc aatttattct acgtgaacat
    23821 cctatttgga tggcagaaga agagattgaa tcaggcatct atgagatgtg cgacatgctc
    23881 cttttgacca aggaagtttc tatcaagaaa taccgagcag agctggctat catgatgtct
    23941 tgcaagcgat ctatcaaggc caatcatcgt attgatgatc attcagctag acaactcctc
    24001 tatcagcttt ctcaatgtga caatccctat aactgtcctc acggacgtcc tgttttggtg
    24061 cattttacca agtcggatat ggaaaagatg ttccgacgta ttcaggaaaa tcacaccagt
    24121 ctccgtgagt tggggaaata ttaaaagtat aaaaaagtct gggaaaaatt ttcaaaatca
    24181 gaaaaacgca taaaatcagg tgttcaaaaa ccttgatttt atgcgtttta tcatagaaat
    24241 atttacttca ttttttccta attcttttcg aaactctttt taaaccacgt cagttttatc
    24301 agtaatctca aaacagtgtt ttgagctaat tttgccagtt ttgtctgtaa catcgaagtt
    24361 gtgttttacc actctgcgac tggtttccta gtttgctcta tgattttcac agagtattaa
    24421 attgcgattt tgccaagttt ctttattcgt ctaaaagtag agtctgttct atgcgtctaa
    24481 tgtacgaatt aggttgacca tttcaatagc tccttgtgca cactcagaac ccttatttcc
    24541 tgctttagta ccagctcgtt ctatggcttg ttcaattgta tctgtcgtta acacaccaaa
    24601 cataacagga atttcgctat ttaaactgat ttgggcgatt cccttagata cctcgctaca
    24661 tacataatca taatgacttg tattccctct aatgacagct cccaagcaga taattgcatc
    24721 atatttttta ctttttgcca tttttgatgc aatcagtggt atttcaaaag ctcctggaac
    24781 ccaggctacc tcgatatctt tctcgtttac attctctctt ttgagattat ctagtgctcc
    24841 agataataat tttgaagtta taaattcatt aaatctcgct acaacaatac ctattttaat
    24901 attgtttgct actaaattac cttcataagt gttcatttat ttttcctcca tatttaaaat
    24961 gtgacccatt cgatttttct ttgtttctaa ataaaaacta tcgtaaggat tggcttctat
    25021 ttcgattgat attctactgg aaatggtaat tccatatttt tctaactgtt caaccttgtc
    25081 aggattattt gtcagtaaat gaagtgactg aagtcccaga tctttaagca tttgtgctcc
    25141 aatatgatat tctcttaaat caccttcaaa gcctaatgca agattggcat caagcgtatc
    25201 catgccttga tcttgtaaat gataggcttt taatttattg ataagtccaa ttcctcgtcc
    25261 ctcctgtcgc aagtaaagta agacacccga accattctca acaatcattt tcatagcttt
    25321 atcgaattgc tgtccacaat cgcaacgtaa agagcctaaa acatctcctg ttaaacattc
    25381 ggagtggacc cgacataata cattggcttc atcctctatg tttcccataa taagagcaag
    25441 atgatgttcc ccatttagtt tatctatata gctaattgct ttgaaattac cgtatctagt
    25501 aggcatattg acagttgaaa ctcgttctac cagctgatca tatacttttc tatattcttg
    25561 taattctttg atggtaatta gtggaatgtt gtgtttcttc gagaactgaa ttaaatcatc
    25621 tgttctcatc attttgccat catgattcat tatttcacaa cataggccac actcttttag
    25681 tccagctaat tttaataaat caacagttgc ttctgtgtgt ccatttcttt ctagaacacc
    25741 accttttttt gcaattaaag gaaacatgtg tcctggcctg cgaaaatcag agggtgttat
    25801 atcttcagct acacacatac gtgcggtcag tcctctttcc tcggcagaaa tacctgtggt
    25861 cgtttcttta taatcaattg aaactgtaaa agcagtctta tgattatctg tattgttttc
    25921 aaccataggt gaaagcatta attgattagc taaactttcg ctcataggca tacaaattaa
    25981 tcctttggca taagtagcca taaaattaac attttctgtt gtagctgctt gtgcagaaca
    26041 aattaagtct ccttcatttt ctctatcctt gtcgtctata acaagaacaa gtcgtccctt
    26101 ctgcaatgct tctaatgctt cttgtatttt tcgatattcc attgactgat tatcctttct
    26161 gctaaaatcc attttgatat aatagttcct tagatatttc tgattttgga gagttatcca
    26221 tcagtttttg cacatattaa cacaaaaagg g
//
LOCUS       DAVHLA010000029        25780 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVHLA010000029 DAVHLA010000000
VERSION     DAVHLA010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25780)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25780)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25780
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.029"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(303..590)
                     /locus_tag="VVO77_001389"
     CDS             complement(303..590)
                     /locus_tag="VVO77_001389"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEU5693396.1"
                     /translation="MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSK
                     WKDISNHHDSESFFANLGCPRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            899..1171
                     /locus_tag="VVO77_001390"
                     /pseudo
     CDS             899..1171
                     /locus_tag="VVO77_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514870.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1281..1484)
                     /locus_tag="VVO77_001391"
     CDS             complement(1281..1484)
                     /locus_tag="VVO77_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEU5693397.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(1515..2123)
                     /locus_tag="VVO77_001392"
     CDS             complement(1515..2123)
                     /locus_tag="VVO77_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU5693398.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            complement(2154..2324)
                     /locus_tag="VVO77_001393"
     CDS             complement(2154..2324)
                     /locus_tag="VVO77_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEU5693399.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            complement(2336..2902)
                     /gene="amaP"
                     /locus_tag="VVO77_001394"
     CDS             complement(2336..2902)
                     /gene="amaP"
                     /locus_tag="VVO77_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEU5693400.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            complement(2986..3150)
                     /locus_tag="VVO77_001395"
     CDS             complement(2986..3150)
                     /locus_tag="VVO77_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEU5693401.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            3593..5074
                     /locus_tag="VVO77_001396"
     CDS             3593..5074
                     /locus_tag="VVO77_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU5693402.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            5436..6437
                     /locus_tag="VVO77_001397"
     CDS             5436..6437
                     /locus_tag="VVO77_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU5693403.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILEKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            6588..7505
                     /locus_tag="VVO77_001398"
     CDS             6588..7505
                     /locus_tag="VVO77_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU5693404.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            7516..8406
                     /locus_tag="VVO77_001399"
     CDS             7516..8406
                     /locus_tag="VVO77_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU5693405.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            8435..10051
                     /locus_tag="VVO77_001400"
     CDS             8435..10051
                     /locus_tag="VVO77_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU5693406.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVENLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            10061..11380
                     /locus_tag="VVO77_001401"
     CDS             10061..11380
                     /locus_tag="VVO77_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEU5693407.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEETGVRQVQNMAFSDDGIHFEKIEQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKNNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKCFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDIDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(11590..11662)
                     /locus_tag="VVO77_001402"
     tRNA            complement(11590..11662)
                     /locus_tag="VVO77_001402"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11627..11629),aa:Lys,seq:ctt)
     gene            complement(11927..13198)
                     /locus_tag="VVO77_001403"
     CDS             complement(11927..13198)
                     /locus_tag="VVO77_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEU5693408.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            13468..13668
                     /locus_tag="VVO77_001404"
     CDS             13468..13668
                     /locus_tag="VVO77_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693409.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQ"
     gene            13872..14051
                     /locus_tag="VVO77_001405"
     CDS             13872..14051
                     /locus_tag="VVO77_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693410.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            14188..14367
                     /locus_tag="VVO77_001406"
     CDS             14188..14367
                     /locus_tag="VVO77_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEU5693411.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERLITIPHGE
                     LNKYTERGIRKQAGL"
     gene            14404..14856
                     /locus_tag="VVO77_001407"
     CDS             14404..14856
                     /locus_tag="VVO77_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEU5693412.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            15147..15617
                     /locus_tag="VVO77_001408"
     CDS             15147..15617
                     /locus_tag="VVO77_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEU5693413.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFIMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            15673..16215
                     /locus_tag="VVO77_001409"
     CDS             15673..16215
                     /locus_tag="VVO77_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693414.1"
                     /translation="MLEKVKQFFRSRSAKTEPSVDILPRNRFEDLDFERVLKSGARRL
                     VNEEGRYAEDGKITELEFPEDFAEFEFLVGFKTEEEEQFQQLLARLNSIDNAIQSYLE
                     SEMQQPIPQYAKDLGYTQKRWEKTFYFHPWILSGEENPPNLRYVADYVNDEFTVYFAK
                     KHGRWQAYWDAECQKVIEES"
     gene            16265..16429
                     /locus_tag="VVO77_001410"
     CDS             16265..16429
                     /locus_tag="VVO77_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7,8-dihydro-8-oxoguanine-triphosphatase"
                     /protein_id="HEU5693415.1"
                     /translation="MELLNSRMDFQGCKIALFCGDKLLTILRDDKDDIPCPNMWELPG
                     GGKSVRENLI"
     gene            16539..17573
                     /locus_tag="VVO77_001411"
     CDS             16539..17573
                     /locus_tag="VVO77_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU5693416.1"
                     /translation="MKKSDVLDLIKYHYEGRETEFRNQSIAIARNFNKHGDTQIAQYI
                     MGLMSQSDRFMPQIENPSEYLTPAKLDIGPLPLPLSIMNDLKGIINAVNHHIGINKFL
                     FVGSPGTGKTESVKQVARLIGKELLVVDFSHLVDSKLGQTVKNLATLFNEINNLPFKQ
                     NYIILFDEIDSIVLDRVNQNDLREMGRVTSAFLKELDRLSPEIVLIATTNLFENLDKA
                     VTRRFDAIIDFDRYTDEDKVEVATIILNELLKQFKNVARDLKLFKKIINSANVIPNPG
                     DLRNSIRTSLAFSDPSDPHDYQKRLLRSLHNGRNLSISKLSKLGFTVREIEILTGISK
                     SSVSRELSED"
     gene            17575..19818
                     /locus_tag="VVO77_001412"
     CDS             17575..19818
                     /locus_tag="VVO77_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008288790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HEU5693417.1"
                     /translation="MNTLLTLRGKSFTPKSAKGRGPITIPADSIVTLNHLNELYTSLE
                     RVKEYWSNNTIIDGVLISVYYNRVLAKSNRIDGFFNVGGGNAIPNETIVGAKFSNDKS
                     RHIITHYISKEVLDKTIEHTKKVITIFKDYFASAPMTSMVFSDSSKFNQIDYSKYGLS
                     KSKFKQYLRDACFVKGFGIEQADMSTIRNSIVTIYDVKTNLLTLLKQLDIDVSEANIM
                     DQTTVLLDEKNIELLLLKAPYLVSMIVEDFSSLSPENFYNDGNTFYNNLPFPTNEPII
                     GVIDTLFDDRVYFNEWVEYHDLISPDISKGSQDYKHGTAVSSVIVDGASLNPKLDDGC
                     GRFRVRHFGISLQSGFNSFTIIKQIREIVSQNPDIKVWNLSLGSNDEIRENFISVEGS
                     LLDEIQFDNDVIFIIAGTNGIAPDGQRKKIGAPADSLNSIIVNSVDFSNQVVSYSREG
                     VVLSFFIKPDVSYYGGGNGDFINVCEPLGLARVAGTSFAAPFIARKMAYLIHIMGLSR
                     EEAKALLIDSAIPWNDKKTFADISLLGYGVVPIKIEDILSTPDDEIKFIVSDVSRAYE
                     TYNYDFPVPISKEHYPYVAKATMCYFPKCSRNQGVDYTNTEMQLSLGVLDKKGIKTIN
                     NDNQYSENAPGYVREKSARNIFRKWDNVKHLGEKFSSRKKAKPILNPSNPQWGMSVKT
                     IERLRNDDGYGIRFGVVVTLKELNGVNRIEDFIQQAELRGWLVNRLQVEAQVDLFNSL
                     NEEIEFE"
     gene            19869..20888
                     /locus_tag="VVO77_001413"
     CDS             19869..20888
                     /locus_tag="VVO77_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001028052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEU5693418.1"
                     /translation="MNITYIVGNGLDLQYGLKTRYKDFYEFQNRTYISRKENEEEYSN
                     LIYESLFSDTVNDYENWSDFELSIGKLTKDNDLISSSIEIKEKFIDDFSEIVDDLREY
                     LRIQQEKNLEKGNAIDFISTLDNMRTSLPVINQPAIDKKYNENLYQHDIVNILTLNYT
                     NVIDKLYNESAKSFSNQLRTNNYKFHIAPPIHAHGTVDICTVLGVSDETQISNSFDEE
                     QKESLIKNLVLKNYRENMDVKNSDIIKNSDIIILYGVSLGETDGYIWNQIAEQSIRSS
                     VPVIIYHYVPHFDAGNPTRVKRLYRNVEDKFIQNSGIDLELEKKLRDNLIVVIGKTIF
                     NLMER"
     gene            20901..21851
                     /locus_tag="VVO77_001414"
     CDS             20901..21851
                     /locus_tag="VVO77_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEU5693419.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARLAELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     IFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVVAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDKW
                     DMVRELAESAGFFLETHMVQGEWNACVFKKTKDISGVIGG"
     gene            21853..22596
                     /locus_tag="VVO77_001415"
     CDS             21853..22596
                     /locus_tag="VVO77_001415"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEU5693420.1"
                     /translation="MQQYFVKGSAISPVTIENKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDSIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     AGLGPRILRAETAPLYALSALSVLVELEK"
     gene            22607..24403
                     /gene="pepF"
                     /locus_tag="VVO77_001416"
     CDS             22607..24403
                     /gene="pepF"
                     /locus_tag="VVO77_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEU5693421.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETA
                     ASVALTFFDDALVAADEEVLDRLGKLPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            complement(24463..24735)
                     /locus_tag="VVO77_001417"
                     /pseudo
     CDS             complement(24463..24735)
                     /locus_tag="VVO77_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433071.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            24723..24905
                     /locus_tag="VVO77_001418"
                     /pseudo
     CDS             24723..24905
                     /locus_tag="VVO77_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
     gene            complement(25029..25118)
                     /locus_tag="VVO77_001419"
                     /pseudo
     CDS             complement(25029..25118)
                     /locus_tag="VVO77_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(25115..25648)
                     /gene="queF"
                     /locus_tag="VVO77_001420"
     CDS             complement(25115..25648)
                     /gene="queF"
                     /locus_tag="VVO77_001420"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HEU5693422.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWAMQHYETVEAVTFAYGQRHHLE
                     IQINREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISINPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
BASE COUNT         8237 a         4371 c         5232 g         7940 t
ORIGIN      
        1 atataattta tttcatattt tgtaaggtca gtgtgaaaat atttaaatag acttcctgta
       61 aaaactggat ttaacgccct ccatttgtca aattaagcta gacagtctta ccaactcaga
      121 aaatacctga tgaggtattt ggtatccaaa ggatttaggt gggatgtgat ttcttgaggc
      181 tgggaaaaag tctttaaaat taaaaaatgt ataatatcag gtgttggaaa aactttgata
      241 ctatgcgttt tattgtggga atatttattt cattttctcc tgaaattgag tttttaccca
      301 gcctaaaatt cttgactgac ttcgttgaaa tctgtctgct ttggcaagtc atgacacctt
      361 aaaagtctat ttgaatgttc gttgagacac cgctgtcttg gacatcctag attcgcaaaa
      421 aagctctcac tatcgtgatg attggaaata tctttccatt ttgaaaactc ttttccacag
      481 tcaaacgtaa tagatttaaa gaggttcact agaaattgtg ccagccaccc ttggatggat
      541 tctgccatat cctttgcctt acgactcttg gtcttcaaac tgacaatcaa ttgactatac
      601 ctgttcgctc acaaatagga gagaactttt tacgaaaatc taatgaatat gccacaagaa
      661 cattataccg caacgtgtac tatttttggt tcattttact atagaaacta ttgaagcacc
      721 tgtacgaaaa tatagtagat tgaaactaga atagtacacc tctacttcta aaacattgtt
      781 agaaatcgat ttgactgtcc cgatcgattc gtcctgttat tatttcattt tactatacat
      841 tatgaaaaag gggagataga aagcaaacag ccttgaaatc aatgttgact gcgattatga
      901 acctgaatca gcccctcaaa agggactgta tatgaatgaa cgttaccagt gtttaaaaac
      961 taaagaatat caggcacttt tatcttccaa gggtagacaa attttcgcta aacgtaagat
     1021 tgatatgaaa tctgtctttg ggcagataaa ggtttgtttg ggttataaga gatgtcatct
     1081 gagaggtaag cgtcaagtga gaattgacat gggattcata ctcatggcca acaacctgct
     1141 gaaatataat aagagaaaga ggcaaaatta aaaagctaga gttccgcaat tgggaatctc
     1201 tagctttttg ttttctgaga atcatcttga ctcagactct tttgactaat gttaccaaaa
     1261 agataaagta acttttaacc ttatttatcg tcgccactca acatgttttt aacaccttct
     1321 acagcacctt ctacagcgtc tttagcgtct tcggcaactt cttttacttt agaaacaact
     1381 ttttcagctg ctccttcttt ttccattttt tcatcaccga tggctttccc aacaccttct
     1441 ttaatagaac ctttagcttg atttaatttt tcttctactg acatgataat ttctcctgtt
     1501 atatttattt tatcttagtt tacacgagtg ttttcgtgag atactacacc atttgctgca
     1561 cctttaacag cttctacacc ttcgctaact ttttcttgaa cagttgagaa accagatcca
     1621 agaccagatt tagctttttc gaattgttct gaagtgaatt ctcctgttga ttcagcaacg
     1681 tcagatacgc gatcttgaag gcttactgag tctgcttcat gctgttcttt agttttgatg
     1741 tcgacaacgt ttacgttgat ttcaacaatt tccaagtcag tcattttagc aacttctgaa
     1801 gatacgattt ctctgatttc tgaatataaa gctggaacat ttttttggta ctcaacaata
     1861 acgtttaagt caactgcaac ttgtgtttta ccaacttcta cgttaacacc acttgttacg
     1921 tcatcgctgt taacgatttt ttctttaaga tttgagaaga aaccaccatc gattcccaaa
     1981 agacctgaaa cgttttctag tgaaagacca atgatttttt ggataacttt atcttcgtaa
     2041 gtaagttccc ctttgatttc gtgagctaca acagtagcat ctttcttttc tacgttagta
     2101 tttgtgtttt tttcgtttga catatgaaac tcctttaatt aaattagtaa tttttattta
     2161 tctatatagt ttttttcgat atataatcca gctgcaactc ccagtgctcc taaaatcaat
     2221 acaaatattg ttttgaagaa gccaaaggag acaatcaaac aagccagaaa tacgcctatg
     2281 agaccagcga taattggata tcgatattgt ttaagccatt ccatttttta cttccttact
     2341 tcacacgact aacagtcttt ttgttttgag gttttggttg gtaatttttt actgcaactt
     2401 caagttttac ttgacgctca ataccaaaaa actgcttcaa tccattagtt atttcatttt
     2461 gaattatttg gcatctgtca gcgatgttgt ctgaaggaag aattttacct tctacatgaa
     2521 cgaaacattt attttttcgt aaatttacat gaacagttgg gttcttgatc aatctatgat
     2581 cactcaccaa acttctaaca aaaccttcga ttgccgaatt ctttaatttt aatgtatcgt
     2641 ttttagtttc aagttggatt tccaagtaac gtttaggata aaacatcaca actaaaatgg
     2701 ataataaaac taaagttgat agaaccactg tcccccaaaa gacatatcta gcaagataga
     2761 attcaactac ggagttctgt ctccagctaa gtagatgaat acctagatca ctaacttgat
     2821 gataatctat caaaacagga aggaaaattg tcaagattaa aatacagaaa ataatgaaac
     2881 atattttctt tgcttttgac atatacaatc ctttcgattt aacatttaaa ctatttttcc
     2941 cgtcattgat ttaaaaatag tttgctaact ttactggcga aaagtttact ttctacctgt
     3001 aaagaatgac actacagtaa tcacaatcgc tgcacctaca atagatggga gcaaagccat
     3061 tccagcgatt gatggacccc aactacctaa aagagattgt cctgcatatg ccccgactaa
     3121 accagcgaat acatttgcga tgattcccat agaactactt ttttagtgat tttacctgcc
     3181 aagagaccaa taagacctcc agcaataatt gatcacaaca ctgcctaccc tcctttttta
     3241 ttttaatatc aaaaaatcaa tttctttgat taatactatt atataacttt aatatagaaa
     3301 agtcaattat ttcgattgtt attattatat aattttaaaa aatcaaattc tttaattgtt
     3361 gctattatat aatttttaaa attaaaaata taatctttag acttgaattt gattctgtat
     3421 tcacgccctc aatagacggt aaaataagaa aattgtttat atattgtctc cgtagtgtta
     3481 ttatacgaaa taaaagattt taggaaaagt cgttatatca tgctatacct attctttgtg
     3541 gtataattgc aagaggttta atccgataat ttataaagag agaaagatat tcatgagaga
     3601 tttattatct aaaaaaagtc ataggcaatt agaattatta gaattattat ttgaacataa
     3661 acgttggttt catcgttctg aactagcaga gttattaaat tgtacagaac gtgcagtcaa
     3721 agatgatcta tcccatgtta aatctgcttt tcctgacttg atttttcatt cttctactaa
     3781 tggtatacgc attattaata ccgatgatag tgatattgaa atggtttacc atcatttctt
     3841 taaacattca actcattttt cgattttaga attcatcttc tttaatgaag gttgtcaagc
     3901 tgagagtatt tgtaaagaat tttatatcag ttcatcttcg ctctatcgta ttattagcca
     3961 aatcaataaa gtgattaaaa ggcaatttca atttgaagtc agtctgaccc ctgttcaaat
     4021 cattggaaat gagagagaca ttcgttactt ttttgcacaa tatttttcag aaaaatatta
     4081 tttcctagaa tggccatttg aaaatttttc atcagagcca ctatctcaat tgttagaatt
     4141 ggtttataag gaaacaagct ttccaatgaa tttgtcaacg catagaatgc taaagttgct
     4201 cctagttacg aacctatata gaataaagtt tggtcatttt atggaagtag ataaagattc
     4261 ttttaacgac caaagtttgg attttttaat gcaggcagaa ggaatagaag gtgttgctca
     4321 gagttttgaa tcagaataca atatctcttt agatgaagaa gttgtttgcc aattatttgt
     4381 gtcttacttt caaaaaatgt ttttcataga tgaaagtctc tttatgaaat gcgtaaaaaa
     4441 ggatagttat gttgaaaaat cttaccatct attgagtgat tttattgatc agatttcagt
     4501 caagtatcag attgaaatgg agaataagga taatctgatt tggcatctgc ataataccgc
     4561 acatctgtat cgtcaagagt tgtttactga gtttatttta tttgatcaaa aagggaatac
     4621 aatcaggaac tttcaaaata tttttccaaa atttgtttca gatataaaaa aagagctttc
     4681 tcactattta gagactcttg aggtttgttc tagttcaatg atggtaaatc atctatctta
     4741 taccttcatc actcatacca aacatttggt gattaatttg ctacaaaatc agcctaaact
     4801 aaaggtttta gttatgagta attttgatca gtatcatgca aaattcgttg cagagacact
     4861 ttcttattac tgtagcaata attttgaact ggaagtttgg actgaattag aattatcaaa
     4921 ggaatcttta gaagattcac cttatgatat cattatttct aattttatta ttcctcctat
     4981 tgaaaataag agactcatct attcaaataa tataaacacg gtctcactca tatacttgtt
     5041 aaatgccatg atgtttattc gattagatga gtaaccaaaa ataacaaaaa aacgctattt
     5101 cgcgtttgaa ctgtacctca aaagttagac agaaaaaatc taatttttgg ggtgtttttg
     5161 ttaagaaaag accttcaatc atttaagcaa aatgtacatc tagatttata gccctctaaa
     5221 actcttgctt tttttgtaga agatacgaaa aaagccataa aaccaaggct tttcctgttt
     5281 tatgtagatg tttacacatg aaaattgaag tattttcaaa agctaattgg agtgatttta
     5341 ttcatgatgg gataaatgat ctggccaaaa atgattgaga aatagttgct taaaaagcat
     5401 ttgcatgata ctatatattg aaaggaggtg ataatatggt agaacaaaga aaatcaatta
     5461 ccatgaaaga tgttgcttta gaagcaggag ttagtgttgg aactgtttca cgtgtaatta
     5521 ataaagaaaa aggcattaaa gaagtaactt tgaaaaaagt ggaacaagcg attaaaactt
     5581 tgaattacat tccagattac tatgctagag gaatgaaaaa aaatcgaaca gaaacgattg
     5641 caatcattgt accaagtatc tggcatccct tcttttcaga atttgctatg catgtggaaa
     5701 atgaagtcta taagagaaat aacaaattac tcttatgttc tataaatggt acaaatagag
     5761 agcaagacta tctggagatg ttgcgtcata ataaagttga tggagtggtt gccattacct
     5821 atagtccaat tgaacattac ttgacgtcag gaattccctt tgttagtatt gaccgcacat
     5881 actcagatat tgccattcct tgtgtttcat cagataatga tgcaggtgga agagaagcag
     5941 ctaaacaatt aattagtaaa ggatgtcagc atttagcctt tgtgggcgga cataatacaa
     6001 ccattaatga aaccaaacgt cgtagaattt catttgaaaa gtatgtccaa gagcataaaa
     6061 tacctcttag tatttttgat ttggatgaga cagttactga ctattatgga aagctagaga
     6121 gtttcttgga agaaaattct tctatagatg gaatttttac aatcaacgat tttacagctt
     6181 tggatgtgat tgaaatacta gaaaaaaatg gcaaacgtat tcctcatgat gtccaaatta
     6241 ttggatacga tggaattaaa atggctggag atagagatta tctactttca actattgaac
     6301 aaccattgga agaaatggca aaagaagcgg ttcgtatttt gtttgatata attgatggaa
     6361 agactgttaa tttgcagaca atcctaccag taaaatttgt tgaaggaaaa acaacaaaaa
     6421 atgaaaataa gtcttgacag aaagcgctat caatgataga atgaattcag ataaaaagat
     6481 ttatttttaa aacaaaaatg aaacgtttca aaaaaagaaa taaaaagaca gcgccaagcg
     6541 ctatctttta tagaaaaaat gaaacgtttc aaaaaaagga ggttgctatg aatagcaaag
     6601 cgaagcaagt ttctctttgg gaaagaatca agaaacaaaa actcttgtta ttgatgactg
     6661 tccccggttt agttttaacc tttatcttta aatacatccc tatgtatggg gttttaatcg
     6721 catttaaaga ttacaatcct ttaaaaggaa ttttagggag tgattggatt ggtttttctg
     6781 agtttacaaa attcatatcc tctcccaact ttggtatctt gttagccaac acattaaaat
     6841 taagtatcta tggtttattg cttggctttt taccaccaat cattcttgcg attatgctca
     6901 atcaactctt gagtgaaaaa gtcaaaaaac gaattcagct cattttatac gcaccaaact
     6961 ttatctcagt cgttgttatt gtcggtatga ttttcctctt cttttcagtg ggaggaccaa
     7021 tcaacaattt tctttctatg tttggaatga aggctgactt cttgacaaat ccagacttct
     7081 ttagaccctt atacatcttt agtggtatct ggcaaggaat gggctgggct tcaacgctct
     7141 acacggcaac attggtaaat gtagatccag ccttagtaga agcagctcga ctggatggag
     7201 ccaatatctt ccaacgaatc tggcacattg atattccagc tcttaagcct attatggtta
     7261 tccaatttgt tttagctgca ggtggaatta tgaatgtcgg atatgaaaaa gcattcttga
     7321 tgcagacatc gttaaatttg ccaacttctg aaattatctc gacatatgtc tataaagttg
     7381 gtcttgtatc aggagactat tcttactcaa cagcggttgg tttgtttaat gcagtgatta
     7441 acgtagtatt gcttgttgca gttaaccaaa tcgttaaacg catgaataat ggtgaaggaa
     7501 tttaaggagg aaagtatgaa aaattcgatt atggatacaa aatttgatag acgtatctta
     7561 ctcttaaata aaatcattat tgtctttatc gttttgatga ctttgcttcc tttactttat
     7621 atcgtcgtag catcctttat ggatcctaag gttctggtta gtagagggat tagctttaat
     7681 ccagccgatt ggactgtaga aggttaccag cgtgtattca gtgaccaatc tattctaaga
     7741 ggttttatca attctctact atactctttt ggatttgcag ctttaacagt attgctatct
     7801 gtgtttacag cttatcctct ttctaagaaa gacttggttg gacgtcgttg gattaactac
     7861 ttcttgattg tgactatgtt ctttggtggt ggtttagtcc caacttactt gctcgtaaaa
     7921 gaattgggaa tgctcaatac tccatgggct atcattgttc caggtgctgt caatgtttgg
     7981 aatattattc ttgctagggc ctatttccaa ggattgcctg aagaattagt tgaagctgct
     8041 gtcattgatg gagcgaatga cttgcagatt ttctttaaaa tcatgcttcc tcttgcaaaa
     8101 ccaattatgt ttgttctctt cctctatgct tttgtaggac agtggaactc atactttgat
     8161 gcaatgattt atatcaagga tccaaacttg gaaccattgc aacttgtact tcgtaaaatt
     8221 ctcattcaga gccaaccagg tcaagacatg attggagcac aagcggctat gaatgaaatg
     8281 aaacgtttag ctgaattgat taaatacgca actattgtca tttccagctt gccattgatt
     8341 gttatgtatc cattcttcca aaaatacttt gataaaggaa ttatggctgg ttcacttaaa
     8401 ggataaaaaa agaaaaaata aaaggagttt tctcatgaaa ttcaaaacat tctcaaaatc
     8461 agcagttttg ttgacagcta gtttagcagt acttgcagcc tgtggctcaa aaaatacagc
     8521 ttcaagtcca gattataagt tggaaggtgt aacattcccg cttcaagaaa agaaaacatt
     8581 gaagtttatg acagccagtt caccgttatc tcctaaagac ccaaatgaaa agttaatttt
     8641 gcaacgtttg gagaaggaaa ctggcgttca tattgactgg accaactacc aatccgactt
     8701 tgcagaaaaa cgtaacttgg atatttctag tggtgattta ccagatgcta tccacaacga
     8761 cggagcttca gatgtggact tgatgaactg ggctaaaaaa ggtgttatta ttccagttga
     8821 aaatttgatt gataaataca tgccaaatct taagaaaatt ttggatgaga aaccagagta
     8881 caaggccttg atgacagcac ctgatgggca catttactca ttcccatgga ttgaagagct
     8941 tggagatggt aaagagtcta ttcacagcgt caacgatatg gcttggatta acaaagattg
     9001 gcttaagaaa cttggtcttg aaatgccaaa aactactgat gatttgatta aagtcctaga
     9061 agctttcaaa aacggggatc caaatggaaa tggagaggct gatgaaattc cattttcatt
     9121 tattagtggt aacggaaacg aagattttaa attcctattt gctgcatttg gtatagggga
     9181 taacgatgat catttagtag taggaaatga tggcaaagtt gatttcacag cagataacga
     9241 taactataaa gaaggtgtca aatttatccg tcaattgcaa gaaaaaggct tgattgataa
     9301 agaagctttc gaacatgatt ggaatagtta cattgctaaa ggtcatgatc agaaatttgg
     9361 tgtttacttt acatgggata agaataatgt tactggaagt aacgaaagtt atgatgtttt
     9421 accagtactt gctggaccaa gtggtcaaaa acacgtagct cgtacaaacg gtatgggatt
     9481 tgcacgtgac aagatggtta ttaccagtgt aaacaaaaac ctagaattga cagctaaatg
     9541 gattgatgca caatacgctc cactccaatc tgtgcaaaat aactggggaa cttacggaga
     9601 tgacaaacaa caaaacattt ttgaattgga tcaagcgtca aatagtctaa aacacttacc
     9661 actaaacgga actgcaccag cagaacttcg tcaaaagact gaagtaggag gaccactagc
     9721 tattctagat tcatactatg gtaaagtaac aaccatgcct gatgatgcca aatggcgttt
     9781 ggatcttatc aaagaatatt atgttcctta catgagcaat gacaataact atccaagagt
     9841 ctttatgaca caggaagatt tggacaagat tgcccatatc gaagcagata tgaatgacta
     9901 tatctaccgt aaacgtgctg aatggattgt aaatggcaat attgatactg agtgggatga
     9961 ttacaagaaa gaacttgaaa aatacggact ttctgattac ctcgctatta aacaaaaata
    10021 ctacgatcaa taccaagcaa acaaaaacta gaggttgatt atgggagata agaaatacac
    10081 agtagaaaaa gccaatcgtt ttatagcaga aaataaacat ctcgttaata ctcaatataa
    10141 gcctgaagaa catttttcag ctgagattgg ttggatcaat gatccaaatg gatttgtcta
    10201 ttttcgtgga gaataccatc tcttttatca attctatcca tatgatagtg tttgggggcc
    10261 tatgcactgg ggacatgcta aaagtaagga cttggtgact tgggagcact tgccagtggc
    10321 acttgctcct gaccaagatt atgaccgaaa tggttgtttc tcaggctctg ccattgtcaa
    10381 ggatgatcgc ctctggctca tgtacactgg acatatcgaa gaagaaaccg gtgtccgcca
    10441 agtgcaaaat atggcatttt cagatgacgg gattcacttt gaaaagattg aacaaaatcc
    10501 agttgcaact ggatcagact tgccagatga gttgattgct gctgattttc gtgatccaaa
    10561 actctttgaa aaagatggac gctattactc cgtagtagct gccaaacaca agaataatgt
    10621 gggctgtatc gttctactag ggtccgataa cctagtagaa tggcagttcg aatccatctt
    10681 tttaaaaggg gtagaacacc aaggctttat gtgggaatgc ccagattact tcgagttaga
    10741 tgggaaagat tgccttatta tgtcacccat gcgttatcag cgtgagggag actcatatca
    10801 taacatcaac tcatcgcttt tgttcacggg taaggtagat tggggagaaa aatgttttat
    10861 cccagaatca gttcaagaaa ttgatcatgg ccaagacttc tatgcgcctc aaacattgtt
    10921 ggacgatcaa aatcgtcgta tcctgattgc ttggatgcag acatgggggc gtacccttcc
    10981 aacccatgac caagaacaca aatgggcatg tgccatgact ttacctagaa ttttaagatt
    11041 ggaagatggc aaactaagac aattccctgt taaaaaaggc caatatcaaa tccaaataga
    11101 taaagattgt cattaccact taggaaatga tatagattat cttgaatttg gttatgatag
    11161 taatgcgcag caagtttaca ttgatcgtag ccatcttatt caaaaaattc taggtgaaga
    11221 agaacaggac actagtcgac ggtatgtaga tattgaagct aaagaattgg aagttgttct
    11281 agataaaaat tccatcgaga tttttgtcaa tcaaggtgaa gcaagcttga ctgcaactta
    11341 ttacttaacg gtgccagctg agctatcacg aattgattaa aaattaagtt atttctccta
    11401 aagaaaaagt tctctttcta aaatagtgga aagaggactt tttgtgtttt gggtatataa
    11461 gcttagttta tggtatttgt aaaattggtg ttggattatg atttaagcta gttttctaaa
    11521 gaatttgaaa aaaattttat ttaagcaaaa aaaacccttg gttccaaggc ttttcctgtt
    11581 gtatttatat gccccctaca gggatcgaac ctgtgaccca cggattaaga gtccgctgct
    11641 ctgccagctg agctaaggag gcaaagaaaa aagctgtatt ggtgccgaaa cttcacggtt
    11701 tgtattgaac ccgcgcaatt aagcaggtgg gcaactcgct ctaactgaag ctgtttccgt
    11761 gtgagacggc ctacatgctg ttagaagact tttgtttccc taataataca aaaaatagtc
    11821 ggtcaacact taagtgtgaa gtcgtacacc acagcgtttc tatacttata tgataccact
    11881 ttttcaaaaa aaatcaagag gaaagtgcaa ttttttgaaa aggatttcag atttttcgca
    11941 aacggtcgat agcttccttt ctttgagcca aagcccgttc atatttacca gtatcttctg
    12001 cttggaaata gtgatgatta cgaatttttt ctggcagata gtcttgcttg acccaatttc
    12061 caggatagtt gtgtggatag agatagtctt gggcattccc cagttccttg cttccactgt
    12121 agtgcccatc acgtaggtgt cgcggaatag gcaagtgccc tgatgttttg aggtcagcaa
    12181 gtgccttatc catagctaca taggctgagt tggattttgg agaaagggcc aaatcaatca
    12241 cgacattggc aatgagaatg cgggcttctg ggaacccaat cttctgggca gcatccagag
    12301 cagtcacggt atgaatctgg gcctcaggat tggctaagcc gatatcttca taggcgataa
    12361 cagtcaagcg acgagcgaga ctaggcagat ccccagcctc aatcaagcgg gcagtatagt
    12421 ggagactggc atccacatct gagccacgaa tagacttttg cagggcagat agaacatcat
    12481 agtgaccgtc tccatccttg tccatagtga tgtagcttct ctgaagacta ttttccatga
    12541 tgtctaaggt gatgtggcga atgccctcgt cattctcagg ggtagagaga acagctaagt
    12601 ccagtgagtt aaaggcagag cgaaggtctc cgtttgtaga ggttgcgatg aaatccagcg
    12661 catcctcatc tagttctatt ggaaaatcaa aaccacgttc agggttactt agagctatct
    12721 gcagggcctc tttgacgtct tggttagaca gaggttccaa ctcgaaaatt tgaactcggc
    12781 tacgaatggc aggagtgaca gagaagaaag gattttcagt cgttgctcca atcatgatga
    12841 ccagtccact ttccaagaga ggcaagagga agtcttgctt ggtcttatct agtcgatgaa
    12901 tttcgtctag caataggacg agaccaccag aaaatttagc ttcttccgag atttcttgca
    12961 gtcgcttttt actatcaact gtcgcattga aagttcgaaa ggcatacttg gtcgttccag
    13021 cgatggcaga ggcaatactg gttttgccga ttccaggagg gccatataga atcatggagg
    13081 acaggcggtt ggcttccacc atgcggcgga tgatttttcc aggtccgacc agatgctcct
    13141 gaccgatgac ctggtcgatg gttttagggc gcatgcgaag cgcgagattg tctggcatag
    13201 cagtcctttc tagcgtggat ttgagtagaa tgactcatct actatatctt actatgtcca
    13261 ttctagccta ttagttgtga tatttcaatg gttttgtaat aatcagggag tgagatagaa
    13321 tcttttttac tatttaattt aatgaggaga ggtatcagca tgagagattt gattttcctt
    13381 aaagctcaaa ataggatagt tgagcctaaa gaagtggaag tgctgacttg agaaataata
    13441 ttgctgaatg tcattgtatg aactataatg aaaagagagg tgataagcaa tggaaatgat
    13501 ggaccaagtc aggaaatttt gatttttaca aaacaaattc gtcattggat tcttagtgat
    13561 caagttattt cagggaaaag aaaacttttc ttccgggaag atactccaaa agagatttta
    13621 gatttgtacg aaaacattaa atctaaactt gattttgctt accaataagt ttattctaat
    13681 aatgggttga aaaaatatga aaaatagaat aattgatgtt tttgaagtag taaatcgcat
    13741 ccttgtaata actgttgaaa atcctgattt cgaagacttg agagttaatc atactcaatg
    13801 aaaatcaaag agcaaactag gaaactagcc gcaggctgta cttgagtacg gtaaggcgac
    13861 gttgacgtgg tttgaatttg attttcgaag agtatcagtt tgtaaaaatt ggagataaaa
    13921 aatatagagt acgcagtgtt cctatgattc attcaactcc gcctcaatct gtcttagatc
    13981 gagatacttt tacaattgac tatacagatg atgaattgct cgataaagaa gcagttttta
    14041 ctactcatta gaaaaatagg tctgaataaa ttggcttccc ttagaaccac atctaggggc
    14101 ttttatgtat aatagaataa taagtatcac tcctttacaa tacgtgtaac acgtgttata
    14161 atggtgttgt caggaggtaa aagcgctatg cctatgacac aaaaagagat ggttaaactc
    14221 cttacggccc atggttggat aaagactaga ggcggtaaag gctcccatat taaaatggag
    14281 aagcaagggg aaagacttat cacaatccct catggtgagc tgaataagta cactgaaaga
    14341 gggataagaa agcaagctgg gttgtaaaat tcagcccctg ttttttgata tggaggtagt
    14401 gaaatgttag ttacgtatcc agctttattt tattatgacg acacagacgg aacagaagcg
    14461 acttattttg tccatttccc agattttgaa tactcagcta cacaaggaga ggggatttct
    14521 gaggctttgg ctatggggtc ggagtggcta gggataactg ttgcagattt gatagagagt
    14581 gatggagagt tacctcagcc atcagatatc aatagcttgt ctttaattga taatgatcct
    14641 tttaaagatg atgaagattt cgtgtcaacc tatgaccttg ataaatcttt tatttctatg
    14701 gtatctgttg atgtatcaga atacctagga agtcaggaac ccataaaaaa gactttgacc
    14761 ataccaaaat gggcagataa gttgggacga gaaatgggac ttaacttttc tcagactttg
    14821 acagacgcta ttgcagataa gaaagttcaa gcctaagatt aagcgtggta tcgtggtaat
    14881 agtcaataaa aaagcacgtc cacttgtgct agttactcgc ctattgattt tatagattta
    14941 ttagcccttt cgagggcttt ttatattgat ttttatgaga aatgaagaaa tcagactttt
    15001 aagaaaatca ctgataccaa gggtttaaat gaggtaatat ggtataatta ggacataaaa
    15061 taattttgtg gtaagatggt agtatctatt ttagcatatt tccgagcaat cggggcgatt
    15121 aaagagtcgc atagaaagag gacaaaatgg caacatacgg atttttagat gttttagagg
    15181 aagagttgga caagaacttt ccctttgact ttgagattag ctgggacaaa cgcaaccatg
    15241 cggtagaagt gagttttcta ttggaagcgc aaaatgctgc aggtgtggag atggtggatg
    15301 aagacggaga ggtttcatca gatgacattc tttttgagga agcggtcctt ttctacaatc
    15361 ctgccaagtc aacagtcaat gaggaagact atttgactgt tattccttac ctgcctaaaa
    15421 aaggattttc ccgtgaattt ttagcttatt ttgcgctttt ccttaaagat actgctgagg
    15481 ttgggctaga tgtcctcatg gactttttgg aagacccaga agcagaggaa tttatcatgg
    15541 aatggaacca agaagtcttt gaagaaggaa aagttggctt ggaagaggga gaattttatc
    15601 cttatccaag gtattagaaa agattctaag tggacatttt taaataatga attcaaggag
    15661 aagggggaga ttatgctaga aaaagtcaaa cagtttttca ggagcaggtc agctaaaact
    15721 gagccgtcag ttgatattct tccccgcaat cgctttgagg atctagattt cgagagagta
    15781 ttgaagtcag gagctcgtcg ccttgttaat gaggaaggac gctatgctga ggatgggaaa
    15841 atcacagaac ttgaatttcc tgaagatttt gcggaatttg aatttctagt tggttttaag
    15901 acggaggaag aagagcagtt tcagcaacta ttagctcgtt taaatagtat tgacaatgct
    15961 attcagtcct atttggaaag tgagatgcaa caacccatcc ctcagtatgc caaggatctc
    16021 ggctatactc agaagaggtg ggagaaaacc ttttacttcc atccttggat attaagtggt
    16081 gaggaaaacc cgcctaatct tcgctatgtt gcagattatg taaatgatga gtttacggtt
    16141 tattttgcta aaaaacatgg cagatggcaa gcatactggg atgcagagtg ccaaaaagta
    16201 atcgaagaaa gctagctcgt attttcctag agagtaattg ttatcataga aaagagtaaa
    16261 tatcatggaa ttattgaata gcagaatgga tttccaaggt tgcaagattg ccctcttttg
    16321 tggggataag ctactgacga ttttgcgtga tgacaaggac gatatccctt gtcccaacat
    16381 gtgggagttg ccaggtgggg gaaagagtgt cagggaaaat ctgatatagt tttgcattaa
    16441 aagaatatcc tttcaaggtt attctttttt aattttgtcc caaaataatt gactttgtcc
    16501 caaaaatata gtattatttg tataaggagg aatgaatcat gaaaaaatca gatgttcttg
    16561 atttaataaa gtatcattat gagggcagag agacagaatt tagaaatcaa tccatagcaa
    16621 ttgctcggaa cttcaataaa catggtgata cacaaatagc acaatatatt atggggttaa
    16681 tgtctcaaag tgatagattc atgccacaaa tagaaaatcc tagtgagtat ttgactcctg
    16741 ctaaactaga tattggtcct ctcccattgc ctctttcaat tatgaatgat ttaaaaggaa
    16801 taataaacgc tgtcaatcat catattggaa taaataaatt tttatttgtg ggatctccag
    16861 gtactggaaa aactgaaagt gtaaagcagg tggctagact tattggcaag gaattacttg
    16921 tagtagattt cagtcactta gtagatagta agctagggca aacagtcaaa aacttagcaa
    16981 ctctttttaa tgaaatcaat aatcttcctt tcaagcaaaa ttatatcatc ctatttgatg
    17041 aaattgattc catagtgttg gatagggtta atcagaatga tttaagagaa atgggacgag
    17101 tgacttctgc ctttttaaag gagttggata ggctgtcacc agaaattgta ttaattgcaa
    17161 caacaaatct ttttgaaaat cttgataaag cagttacgag aagattcgat gccataattg
    17221 actttgaccg ttatactgat gaagataaag tagaagtagc tactattatt ttaaatgagt
    17281 tattaaagca atttaagaat gtagctagag atttaaaatt atttaaaaaa attatcaata
    17341 gtgccaatgt aataccgaat cctggtgatt tgagaaactc aataagaacg tcattggcat
    17401 ttagtgaccc atcagatccg catgattacc aaaaacgcct gctaagaagt ttgcataatg
    17461 gtagaaattt atctatttct aaattatcga agctaggttt tactgttaga gaaattgaga
    17521 ttttgacagg tatttctaag agtagtgtat cacgagagtt aagcgaggat taaaatgaat
    17581 acattattga cattacgagg taaaagtttt acaccaaagt cagcaaaggg gaggggaccg
    17641 ataacgattc ccgcagattc tattgttacg ctaaaccatt taaatgaact ttatacatcc
    17701 cttgaacgag taaaagaata ttggtctaat aacacaatca ttgatggagt acttattagt
    17761 gtgtattata atcgtgtcct agctaagagc aatcgtatcg atggtttttt taatgtgggt
    17821 ggcggaaatg caattccaaa tgaaacgatt gtgggtgcaa aatttagtaa tgataagagt
    17881 aggcatatta ttacacacta catttcaaag gaagtgttag ataagacaat tgagcatact
    17941 aaaaaagtta taacaatatt caaagattat tttgctagtg ctcccatgac gagtatggtg
    18001 ttctccgact cttcaaaatt taatcaaatt gattattcta agtatggtct gtcgaaatca
    18061 aaattcaaac aatacttaag agacgcttgc tttgtcaaag gatttggtat tgaacaggca
    18121 gatatgtcta ctatacgtaa ttctattgta acaatctacg atgtaaaaac taatctctta
    18181 acattactta aacaacttga tattgatgtt tcagaagcta acatcatgga ccagacaact
    18241 gttttacttg acgaaaaaaa tattgagtta ctactgctaa aagcacctta tctagtatca
    18301 atgatagtag aagatttttc tagcctgtca ccagagaatt tttataatga tgggaacact
    18361 ttttataata atctcccttt tccaactaat gaacctatta ttggtgtcat cgatacgttg
    18421 tttgatgata gagtttattt caatgagtgg gtagagtatc atgatttaat ttcaccagat
    18481 attagcaaag gaagtcaaga ctataagcac ggtacagcag tttcctcggt aatagtagat
    18541 ggagctagtt tgaatccaaa actagatgac ggatgtggaa gatttagagt cagacatttt
    18601 gggatatctt tacagagtgg tttcaattcc ttcacaatta tcaaacagat tagagaaatt
    18661 gtgtctcaaa atcctgatat taaggtttgg aacctttcgc ttggatcaaa tgatgaaatt
    18721 agggaaaact ttatttctgt cgagggttcg ttgttagacg agattcaatt tgataacgat
    18781 gtaattttta ttattgcagg cactaatggg attgcccctg atggacaacg aaaaaagatt
    18841 ggagcaccag cagattcact caattcaatt attgtaaatt ctgttgattt tagcaatcaa
    18901 gtcgtttctt attcacgcga aggagttgtc ctgtctttct ttatcaaacc tgatgtttca
    18961 tactatggcg gggggaacgg agacttcata aatgtttgtg aaccactagg gctggctcga
    19021 gtagctggga ccagttttgc ggctccattt attgctagaa aaatggctta cctcattcat
    19081 attatgggat taagtcgtga agaagcaaag gctttattaa ttgattcagc gataccatgg
    19141 aatgataaaa aaacattcgc agacatttct ttacttggat atggggttgt gccaatcaaa
    19201 atagaagata ttttgtctac acctgatgat gaaattaaat ttatagtctc agatgtttct
    19261 agagcatatg aaacttataa ttatgatttc ccagttccaa tttctaaaga acactatcca
    19321 tatgtagcaa aggccactat gtgctatttt ccaaagtgtt ctagaaatca aggagttgac
    19381 tatactaata cggaaatgca acttagtttg ggagttttag ataagaaagg cattaaaaca
    19441 attaataacg acaatcaata ttctgaaaat gcaccaggat atgtgagaga aaagtcggca
    19501 cgaaatattt ttaggaaatg ggataatgtc aaacatttag gagaaaaatt ttcttctcgt
    19561 aaaaaagcta agccgattct gaatccttct aatcctcaat ggggaatgag tgtaaaaaca
    19621 attgaacggt taagaaatga tgatggttat ggtatccgtt ttggagtagt tgttactcta
    19681 aaggagttga atggtgtcaa tagaatcgaa gattttattc aacaagccga attacgcggt
    19741 tggctagtta atagattgca agtagaagct caagtagacc tctttaatag tttaaatgaa
    19801 gaaattgaat ttgaatagtg gatattttat ccttattcta gatcttagga acacaagagg
    19861 gcaaagatat gaatattact tatatagttg gaaatggttt ggatttgcaa tatggtttga
    19921 aaacaagata taaagatttc tatgaatttc aaaataggac ttacataagt aggaaagaga
    19981 acgaggaaga atattcaaat ctcatttatg agtctctatt ttctgataca gtaaatgatt
    20041 atgaaaattg gtcagatttt gaattgtcaa ttggtaaatt aacaaaagat aacgacctca
    20101 tctcctcaag tatagaaata aaggagaaat ttatagatga ttttagtgaa atagttgatg
    20161 atttaagaga atatctacgc atacaacaag aaaaaaatct tgagaaaggt aatgcaattg
    20221 actttataag cactctagat aatatgagga cctctctccc tgtaattaat caacctgcta
    20281 tcgataaaaa atataatgaa aatctatatc aacacgatat cgtgaatata ttaactctta
    20341 attacacaaa tgtaatcgat aaattatata atgagtcagc aaaatcattt agcaatcaat
    20401 tacgaactaa taattataaa tttcacattg cgcctccaat tcatgcacat ggaacggtag
    20461 atatttgcac agttttagga gttagtgacg agacacagat ttcaaatagt tttgatgaag
    20521 aacaaaaaga atccttaata aaaaatttag ttttgaagaa ctatagagaa aatatggatg
    20581 ttaaaaatag cgatattata aaaaattctg acatcataat tctttatggg gtttctttgg
    20641 gagagactga tgggtatatc tggaatcaga ttgctgaaca atcaatcaga agttctgttc
    20701 ctgtcataat ttaccattat gtacctcatt ttgatgcagg aaaccccact agagtaaaac
    20761 gcttatatag aaatgtagaa gacaaattca tacaaaatag tggaattgat ttagagttag
    20821 agaagaaatt aagagataac cttattgttg ttattggaaa gactattttt aatctgatgg
    20881 aaaggtaagc aaaatacata atggaaacat ggcaagagtt aaaagttaca gtgaagcgtg
    20941 agggagagga gttggtttcc aatctcttga ttgagctggg agcgcaagga gtcgcaatcg
    21001 aagacagtat ggactatgtg ggaaatgttg accgctttgg cgagattttc ccagaggtgg
    21061 agcagcaaga agaaatcgta gtgacagcct actaccctga cacggtggat gtgacagtgg
    21121 ttgaggcgga tttgcaggct cgtctagcag aattgacaga ttttatggat ttgggagagt
    21181 taaaaatagg tacgactgcc ttggctgagg aagactgggc agacaactgg aagaaatact
    21241 atgaacctgc tcgcatcact catgatttga ccatcgttcc ctcttggaca gactatgagg
    21301 cgactgcggg agaaaaaatt atcaagctgg atcctggcat ggcttttggt acgggaaccc
    21361 acccaactac caagatgagc atttttgcct tggaacaggt tcttcgtggt ggcgaaacgg
    21421 tgctagatgt gggaactggt tcaggggttc tctctattgc cagctcgctt ctgggggcta
    21481 aagaaatttt cgcctatgac ctggatgatg tggcagttcg tgtggctcag gaaaatattg
    21541 agctcaaccc tggaatggaa aatatccatg tagtggcagg cgatttgctt aaaggcgtgg
    21601 agattgaagc agatgtcatc gtggcaaaca tcttggcgga tatcctcatt catctgacag
    21661 aggatgctta tcgcttggtt aaggatgaag gttacctgat catgagtggc attatcaagg
    21721 ataagtggga catggtgcgc gagttggctg aatcagctgg atttttcctc gaaactcaca
    21781 tggttcaagg ggaatggaat gcctgtgtct ttaagaaaac caaggatatc tctggtgtga
    21841 ttggaggcta gcatgcagca gtattttgta aaaggcagtg ctatctctcc tgtcactatc
    21901 gagaacaagg aaaccagtaa gcatatgttt caggttatgc gcttgaaaga agaggatgag
    21961 gttaccttag tctttgatga tggcatcaag cgcttggcgc gcgtgctgga tatggaaaat
    22021 cgtcagtttg agttggtcca agaattaaat gacaatgtgg aactaccagt ccaagtgacc
    22081 atcgcatctg gatttcccaa gggagacaag ctggagttca tcgctcaaaa agtaaccgaa
    22141 ctgggtgcta gccaaatctg ggcctttcct gcagactggt cagttgccaa gtgggatggc
    22201 aagaaattgg gtaaaaaagt tgaaaaacta gaaaaaattg cccttggagc agccgagcaa
    22261 agcaagcgta atattgtacc aagtattaaa cttttcgaga aaaaagcaga ttttctagct
    22321 cagctggacc agtttgactc tatcatagta gcctatgaag aatcagctaa agaaggagaa
    22381 gccgctgcgc ttctgcaagc agtcactggt cttgaaacag gagccaaact gctctttatc
    22441 tttggtccag aaggcggtct ctcacctgca gaaatcgaaa gttttgaagc taagggagcc
    22501 gttttggcag gcctaggtcc tcgtattttg cgagcagaaa cagcaccgct ttacgcttta
    22561 tcagccctta gtgttttagt agaattagag aaataagagg aagaaaatgg aacaaaaaca
    22621 ccgttcagaa tttccagaga aggaactctg ggacttaaca gccctatacc aagaccgtga
    22681 ggatttcttg cgtgcaatcg agaaagctcg cgaagacatc aaccagttta gccgtgatta
    22741 caagggcaat cttcacactt ttgaggattt cgagaaggcc tttgcggaat tggaacagat
    22801 ctacattcag atgagccata ttggcaacta tgcttttatg cctcagacga cggactatag
    22861 caatgacgaa tttgccaata ttgcccaagc tgggatggaa tttgaaacag ctgccagcgt
    22921 agccttgacc ttctttgacg atgccttggt ggcagcagac gaggaagtct tggaccgttt
    22981 gggtaaattg ccacatttaa cagctgccat tcgtcaggct aaaatcaaaa aagcccacta
    23041 cttaggggca gatgtggaga aggccttgac aaatctcggt gaagttttct atagtccgca
    23101 ggacatttat actaagatgc gagctgggga ttttgaaatg gctgactttg aagcccatgg
    23161 caagacctat aaaaacagct ttgtcaccta tgagaatttc taccaaaatc acgaggatgc
    23221 tgaggttcgt gagaaatcct tccgttcctt ctcagaggga cttcgtaagc accaaaatac
    23281 ggctgcagca gcctatctgg ctcaggtcaa gtctgaaaaa ctcttggctg atatgaaggg
    23341 atacgactct gtctttgact atcttctagc tgaacaagaa gtggaccgtg tcatgtttga
    23401 ccgccagatt gacctcatca tgaaggactt tgcaccagtc gctcagagat acctcaagca
    23461 tgttgccaag gtaaatggtc ttgaaaagat gacctttgca gactggaaat tggacttgga
    23521 cagcgccctg aatcctgaag tgactattga cgatgcctat gatttggtca tgaagtcggt
    23581 agaacctttg gggcaagaat attgtcagga agttgctcgt taccaagaag agcgctgggt
    23641 ggattttgct gctaacagtg gcaaggattc cggtggttat gcggcggacc catatcgcgt
    23701 acacccttat gtactcatga gctggacagg ccgtttgagc gatgtctata ccttgattca
    23761 tgaaatcggg cattctggtc aattcatctt ttcagacaat caccaaagct atttcaacgc
    23821 ccacatgtcg acctattatg ttgaagcacc gtcaaccttc aatgaattgc tactcagtga
    23881 ttacttagag aaccagtcta atgacccacg tcaaaaacgc ttcgctctgg ctcatcgctt
    23941 gacagacacc tacttccata atttcatcac ccacctcttg gaagccgcct tccagcgtaa
    24001 ggtgtataca ttgattgaag aaggggagac ctttggagca agcaagctca acagcattat
    24061 gaaggaagtt ttgacagatt tttggggcga tgccattgaa atcgacgacg atgcagcttt
    24121 gacttggatg cgccaagctc actactatat gggcttgtat agttacactt actctgctgg
    24181 tcttgtcatc tcgacagctg gttaccttca tcttaaaaac tcagaaactg gagctgaaga
    24241 ctggctcaat ctcctcaaat caggtggtag caagacacca cttgagtcag ccatgattat
    24301 cggtgctgat atttcaacag acaaaccact ccgtgatacc atccaattct tgtctgacac
    24361 agttgaccag attatcgcct acagtgctga gttgggggag taaggggata gagaggttgt
    24421 tatagaatgg gtatggacag ttatttgctt aaaagtccat gtttaaatcc cccattcctt
    24481 ttcgaggaat tctttgccct tctctgtaat ggtaagtgaa cgtggcgttt gtgcagggat
    24541 gaccaattgt ttttcactga aaaattctaa aagagcattg ccgagagctc cgccgacatg
    24601 atttttacgt tcgctccaat ccaaacattt agggcaaaat ttccgttttt tctttttcaa
    24661 ttcatccgta tcaatgtgta attttctttg gaaataagac ttcccagctt cagtgagttg
    24721 gaagtctttt tctgatcgga ttgaagatta ctggactttc agtaaaccca gctcgtagct
    24781 tggcaccagc tgtcttggtg ggcggcgcag cccttcaaca agtttggatt ttcatccttg
    24841 caccaatcgc tggtggagtt cttgcagccc ttgttgcaaa aaatttcctt ggaacagaag
    24901 aataattgaa actcaaaaag ccttgctcct catcttgagg aacagggctt tttcgtatga
    24961 tactcttcga aaatctcttc aaaccacgtc agcttcacct tgccgtaggt atggttactg
    25021 acttcgtcag ttctatccac aacctcaaaa cagtgttttg agtaacctgc ggctaacttc
    25081 ctagtttgct ctttgatttt cattgagtat gactttagcg gttgtcaatt ttctctggat
    25141 aaaggtcgtg ttggaagagg cgttgttctg ccaagccctc atacttagtt ccttgcttac
    25201 cgtagttgta gtaggggttg attgaaatgc caccgcgcgg agtgaatttc ccccagactt
    25261 ctaaatagcg agggtctagc aagttgacca agtctttccc gatggtgttg atacagtttt
    25321 cgtggaaatc tccgtggttt cggtagctaa atagatatag tttgagggat tttgactcga
    25381 cacagagttt gtcaggaatg taggaaatat gaatcgtcgc aaagtctggc tgagcagtga
    25441 tttgtcccag cagagacata tcgaggatat ggtgacgaat gccctgttcc ttagcgattt
    25501 ctctattaat ttgaatttcg aggtgatgac gttggccgta ggcaaaggtg acagcttcga
    25561 ctgtttcata gtgttgcatg gcccagaaaa ggcaggttgt tgaatcttga ccaccactaa
    25621 agacgaccaa ggctgattga cgtttcatag tactccttcc aaaatgggaa atgttcagag
    25681 catgcaaaaa gctcccatta gggagctaaa aaataccaaa tcgagttttt ttagcgatgg
    25741 catatcccaa acatcgtaat attctactta tatagtaaaa
//
LOCUS       DAVHLA010000030        24114 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVHLA010000030 DAVHLA010000000
VERSION     DAVHLA010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24114)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24114)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24114
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.030"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            <1..767
                     /locus_tag="VVO77_001421"
     CDS             <1..767
                     /locus_tag="VVO77_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU5693423.1"
                     /translation="PAPTPEAPAPAPKPAPAPKPAPAPKPAPAPKPETPKTGWKQENG
                     MWYFYNTDGSMATGWLQNNGSWYYLNANGAMATGWAKVNGLWYYLNSNGAMATGWLQY
                     NDSWYYLNTNGAMATGWLEYNGSWYYLNANGAMATGWLEYNGSWYYLNSNGAMATGWL
                     QYNGSWYYLNANGAMATGWAKVNGSWYYLNANGSMATGWVKDGDTWYYLEASGAMKAN
                     QWFKVSDKWYYVNGLGALAVNTTVDGYTVNENGEWV"
     gene            1168..2289
                     /gene="mnmA"
                     /locus_tag="VVO77_001422"
     CDS             1168..2289
                     /gene="mnmA"
                     /locus_tag="VVO77_001422"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEU5693424.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAITLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLKKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            2430..2885
                     /locus_tag="VVO77_001423"
     CDS             2430..2885
                     /locus_tag="VVO77_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU5693425.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYIIGGA
                     IQVNEKTEDAVVREVKEELGVKAQAGQLAFVVENRFEVDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            2895..4808
                     /gene="mnmG"
                     /locus_tag="VVO77_001424"
     CDS             2895..4808
                     /gene="mnmG"
                     /locus_tag="VVO77_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEU5693426.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWASFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(5003..6682)
                     /locus_tag="VVO77_001425"
     CDS             complement(5003..6682)
                     /locus_tag="VVO77_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEU5693427.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(6684..6917)
                     /locus_tag="VVO77_001426"
     CDS             complement(6684..6917)
                     /locus_tag="VVO77_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEU5693428.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            complement(7735..7887)
                     /gene="cibB"
                     /locus_tag="VVO77_001427"
     CDS             complement(7735..7887)
                     /gene="cibB"
                     /locus_tag="VVO77_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEU5693429.1"
                     /translation="MMKDLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(7889..8074)
                     /gene="cibA"
                     /locus_tag="VVO77_001428"
     CDS             complement(7889..8074)
                     /gene="cibA"
                     /locus_tag="VVO77_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HEU5693430.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            8252..8935
                     /gene="tsaB"
                     /locus_tag="VVO77_001429"
     CDS             8252..8935
                     /gene="tsaB"
                     /locus_tag="VVO77_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEU5693431.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAYTLNIELVGMSSLLALVPY
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMAEAHLPFERVIELIKGASQVTFVGEVGPF
                     VEQIQKHLPRTDYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            8932..9369
                     /gene="rimI"
                     /locus_tag="VVO77_001430"
     CDS             8932..9369
                     /gene="rimI"
                     /locus_tag="VVO77_001430"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEU5693432.1"
                     /translation="MIEIKRIQQQPALAQDIYAVMAAVYPVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLTVQETLFEAEVLQIAVKGACQGQGIASALFAQLPTDKEIFLEV
                     RQSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            9359..10369
                     /gene="tsaD"
                     /locus_tag="VVO77_001431"
     CDS             9359..10369
                     /gene="tsaD"
                     /locus_tag="VVO77_001431"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEU5693433.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLYHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(10409..11715)
                     /locus_tag="VVO77_001432"
                     /pseudo
     CDS             complement(10409..11715)
                     /locus_tag="VVO77_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(11991..12342)
                     /locus_tag="VVO77_001433"
                     /pseudo
     CDS             complement(11991..12342)
                     /locus_tag="VVO77_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(12449..12742)
                     /locus_tag="VVO77_001434"
                     /pseudo
     CDS             complement(12449..12742)
                     /locus_tag="VVO77_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            12985..14159
                     /locus_tag="VVO77_001435"
                     /pseudo
     CDS             12985..14159
                     /locus_tag="VVO77_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            14152..15105
                     /locus_tag="VVO77_001436"
     CDS             14152..15105
                     /locus_tag="VVO77_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU5693434.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCLHQSYKNIEVIIID
                     DNYSNVNLRNKIIHQFGYTNHRIKLILSNEDLGATNARNIGIKNSRGKYISFLDDDDE
                     YMPDRILKLMACFKKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIA
                     GTSFWLCKKEVLELINGFEKIDSHQDGVVLLKLLAQGYQIDIVREFLVNYYAHSKENG
                     ITGVTQKTINADEEYYNYCRKYFNLLSFNERILVTKKYYSLNIKRLLLIGDKCKALKV
                     IKKAREEKIFNEFLFLKYMLLYHFGFFYCIYDNYVQLKFRK"
     gene            15115..16731
                     /locus_tag="VVO77_001437"
     CDS             15115..16731
                     /locus_tag="VVO77_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5693435.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            16992..17420
                     /locus_tag="VVO77_001438"
     CDS             16992..17420
                     /locus_tag="VVO77_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693436.1"
                     /translation="MSEIVEMSKKISDLNDKKEFHKKNCELRFQDSVLDNINSVPGTT
                     HLFSCLNIQTLVKIILYIFRYNSCMKIFNFRDKELIFFNKIVNGLIQNIEENLEDDIE
                     RILKYLYICLFNEIFIIKNKVNFFDDVEFNQTLSEFLDKL"
     gene            17432..18181
                     /locus_tag="VVO77_001439"
     CDS             17432..18181
                     /locus_tag="VVO77_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HEU5693437.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFQYVSDSSMVGYMGKTKELKMYQEELDEKNYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            18194..19366
                     /locus_tag="VVO77_001440"
                     /pseudo
     CDS             18194..19366
                     /locus_tag="VVO77_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
     gene            19761..20624
                     /locus_tag="VVO77_001441"
     CDS             19761..20624
                     /locus_tag="VVO77_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEU5693438.1"
                     /translation="MIERMELGEFYKELRLARKLKQSDVACAGLTASQLSKFELGQSM
                     LSADKLILAIQGINMNFDEFGHKLNNYQESPHMRFGRKVVDRFAHQDIVGLEQLLEEV
                     EQEQMAETYRRLNAIVIKDAIHSLDKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKSGFLNIISELMERKLFSYIPIFE
                     AELESMLRPYDVFEKVLWQFLKKMSIFLQTKGSNQKEIEHFIQSLQVLENPQLIVLFE
                     LRLQQYKKLID"
     gene            20910..21143
                     /locus_tag="VVO77_001442"
     CDS             20910..21143
                     /locus_tag="VVO77_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693439.1"
                     /translation="MLNLQFAETMELTEAELQDVRGGNLVNSMGGGGRSGISGWGVPG
                     IYPGWGNQGMSPNRGAFDWTIDLADGLFGRRRR"
     gene            21165..21842
                     /locus_tag="VVO77_001443"
     CDS             21165..21842
                     /locus_tag="VVO77_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU5693440.1"
                     /translation="MKKMKEVKFHLATGLLILTYYLIFNVTSDLDFMVALSDNMYYVF
                     QVLLVLILGTIATIAFVKSEHWKECGRFQFRWSYLGVFLLSFFLLFVWANLTTYIFPR
                     TQNGSTVVEVATNLTGISYFVTRILYTSIIAPVSEEVVCRGLLMTSLSKVKRYYLDVL
                     VSAAIFGAMHVLQYGWITTDFIKYFGMGLIFCMMFRYTRSIYWAIALHASWNSFLLIV
                     TLLVFGY"
     gene            21854..22519
                     /locus_tag="VVO77_001444"
     CDS             21854..22519
                     /locus_tag="VVO77_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU5693441.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVTGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVVWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEEIIHRGLVMTALEKGKKWGLDVL
                     GSAILFGVSHISNHGWVLTDFFVYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            22591..23817
                     /locus_tag="VVO77_001445"
     CDS             22591..23817
                     /locus_tag="VVO77_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU5693442.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISEILPQILQIFLGVLADFQHHRVLKYTVISFAKFLLYSIVSLSLSGQSFSLL
                     LVAFICLINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTINYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
BASE COUNT         7333 a         4118 c         5126 g         7537 t
ORIGIN      
        1 ctccagctcc aactccagaa gccccagctc cagctcctaa accagctccg gctcctaaac
       61 cagctccggc tcctaaacca gctccagctc ctaaaccaga aactccaaaa acaggctgga
      121 aacaagaaaa tggtatgtgg tacttctaca atacggatgg ttcaatggca acaggctggc
      181 tacaaaataa tggctcatgg tactacctca acgctaatgg tgctatggca acaggttggg
      241 ctaaagtcaa cggcttatgg tattacctca acagcaatgg cgctatggcg acaggatggc
      301 tccaatacaa tgattcatgg tactacctca atactaatgg tgctatggcg acaggttggc
      361 tagaatacaa tggttcatgg tactacctca acgctaatgg tgctatggcg acaggttggc
      421 tagaatacaa tggctcatgg tactacctca acagcaatgg cgctatggcg acaggttggc
      481 tccaatacaa tggttcatgg tactatctaa acgctaacgg cgctatggca acaggttggg
      541 ctaaagtcaa cggttcatgg tactacctca acgctaacgg ttcaatggca acaggttggg
      601 tgaaagatgg agatacctgg tactatcttg aagcatcagg tgctatgaaa gcaaaccaat
      661 ggttcaaagt atcagataaa tggtactatg tcaatggctt aggtgccctt gcagtcaaca
      721 caactgtaga cggatatact gtcaatgaaa acggtgaatg ggtttaagcc gattaaatta
      781 aatcatgtta agaacatttg acattttaat tttgaaacaa agataaggtt cgattgaata
      841 gatttatgtt cgtattcttt aggtacctat cttatgattt caggaaatgt cattaaaaaa
      901 acgactcctt ttctctaact tgaaaaatag attagagaaa atgggttgtt ttatttatta
      961 tagttatttg aatgaagata agaagaaggt atactcacat cattcacata atctgtatat
     1021 tgactataag ttttaaaaaa caatttttaa gctcttcctt gtcttctcta accaagcgtg
     1081 ttataatgaa tactgctcaa gcgaccttca atcgtgaagc acacacgacc ttcaatcgtg
     1141 aataaacgaa tagatgggag acttaccatg agtgataact ctaaaacacg tgttgtcgtg
     1201 gggatgagtg gtggtgttga ttcgtcggtg acggctcttt tgctcaagga gcagggctac
     1261 gatgtgatcg gtatcttcat gaagaactgg gatgacacag atgaaaacgg cgtctgtacg
     1321 gcgaccgaag attacaagga tgtggttgcg gtggcagacc agattggcat tccctactac
     1381 tctgtcaatt ttgaaaaaga gtactgggac cgcgtttttg agtatttcct agcggaatac
     1441 cgtgcagggc gcacgccaaa tccggacgtt atgtgcaaca aggaaatcaa gttcaaggcc
     1501 tttttggact atgccataac cttgggggca gactatgtag cgactgggca ttatgctcga
     1561 gtggcgcgtg atgaggatgg cactgttcac atgcttcgtg gcgtggacaa tggcaaggac
     1621 cagacctatt tcctcagcca actttcgcaa gaacaacttc aaaaaaccat gttcccacta
     1681 ggacatttga aaaagcctga agttcgaaaa ctagcagaag aagcaggtct ttcgactgct
     1741 aagaagaaag actcgacagg gatttgcttt atcggagaaa agaactttaa aaactttctc
     1801 agcaactacc tgccagctca gcctggtcgt atgatgactg tggatggtcg tgatatgggc
     1861 gagcatgctg gtcttatgta ctatacaatc ggtcagcgtg gcggactcgg tatcggtggg
     1921 caacacggtg gtgacaatgc cccttggttc gttgtcggaa aagatctaag caagaatatt
     1981 ctctatgtag gccaaggttt ctaccatgat tcgctcatgt caaccagcct agaggctagc
     2041 caagtccact ttactcgtga aatgccagaa gagtttacgc tagaatgtac ggctaaattc
     2101 cgttaccgtc agcctgactc taaggtgacc gtccatgtca aaggagacaa ggcagaagtt
     2161 atctttgcgg aaccacaacg cgcgattaca ccaggacagg cagttgtctt ttacgatggc
     2221 gaagagtgtc taggtggcgg tttgattgac aatgcttacc gcgatggaca agtttgtcag
     2281 tacatttaga ttgacaaatt ttctcaattt gctacaataa taacagcaat agaaatgatg
     2341 gtcaaagctc atggatgttg caggcttttt tgtcctgcac ttctttggag ttttgactgt
     2401 ttttgtgtcg tttaagggaa aggacaagaa tgactcaaca agactttcgg acaaaagtag
     2461 acaatacggt ttttggtgtt cgggcgacag ccttgattgt ccaaaatcac aagcttctag
     2521 tcaccaaaga caagggcaag tattacatta tcggcggtgc gattcaagtt aacgaaaaaa
     2581 cggaagacgc ggtagtccgt gaagtgaagg aagaactggg tgttaaagct caagctgggc
     2641 agctagcttt tgtggttgaa aatcgttttg aagtggacgg cgtttcctat cacaatatcg
     2701 agtttcatta tctggtggat ttgcttgaag atgccccgtt gaccatgcag gaagatgaga
     2761 aaaggcagcc ctgtgagtgg attgacttgg ataagcttga ggatatccag ctagttccag
     2821 cctttttaaa aacagcccta ccagattggg aaggccaact aagacacatt catcttgagg
     2881 aataggagag aaacatgact tatcatttta ctgaagaata cgatattatt gtaattggtg
     2941 cgggacacgc tggggttgag gcttccttgg ccgctagccg tatgggctgt aaggtcctgc
     3001 ttgcgaccat caatattgaa atgctggctt tcatgccttg taatccctct atcggtggtt
     3061 ctgccaaggg gattgtcgtg cgtgaagtcg atgccctcgg tggcgagatg gccaagacta
     3121 ttgacaagac ttacatccag atgaagatgc tcaacacagg gaaggggcca gctgttcgtg
     3181 ctcttcgtgc gcaggctgac aaggaacttt actctaagga aatgcgcaag acagttgaaa
     3241 atcaagaaaa tctgaccctt cgtcaaacca tgattgatga gattttggtg gaagatggta
     3301 aggttgtcgg tgtgcgtaca gccacccatc aagaatatgc tgctaaggct gttattgtga
     3361 cgacagggac tgctctccgt ggggaaatta tcatcggaga cctcaagtac tcatcaggtc
     3421 ctaaccacag cttggcttct attaacctag ctgacaatct caaggaactg ggtctcgaaa
     3481 tcggtcgttt caagacagga acccctccac gtgtcaaggc ctcttctatc aactacgacg
     3541 tgacagaaat ccaaccagga gatgaagcac ctaatcactt ctcatacact tcacgtgatg
     3601 aggattatgt caaggaccaa gtaccatgct ggttgaccta caccaatggt accagtcatg
     3661 agattatcca aaacaacctc caccgtgcgc ctatgtttac aggtgtggtc aagggagtgg
     3721 ggcctcgtta ctgtccgtcg attgaagaca agattgtgcg ctttgcggac aaggaacgtc
     3781 accaactctt ccttgagcca gaagggcgca atactgagga agtctatgtt caaggacttt
     3841 caaccagtct gcctgaggat gtccagcgtg acttggttca ttccatcaaa ggtttggaaa
     3901 atgcagagat gatgcggaca ggttatgcta ttgagtatga tatggtcttg cctcatcagt
     3961 tgcgtgcgac tttggaaacc aagaaaatct caggtctctt cactgctggt cagacaaatg
     4021 gaacatcagg ttatgaagaa gctgctggcc aagggattat cgcgggtatc aatgcggctc
     4081 tgaaaatcca aggcaagcct gagttgattt tgaagcgcag tgacggttat atcggggtga
     4141 tgatcgacga cttggtgacc aagggaacca ttgaacccta ccgtctcttg acaagtcgtg
     4201 ctgaataccg tctcattctt cgtcatgaca atgctgatat gcgcttgact gagatgggac
     4261 gcgagattgg ccttgtggat gatgaacgct gggctagttt tgaaatcaag aaaaatcaat
     4321 ttgataatga gatgaaacgc ctagacagta tcaaactcaa gccagtcaag gaaaccaatg
     4381 ctaaggttga ggaaatgggc ttcaagccgt tgacagatgc ggtgacagcc aaggaattcc
     4441 ttcgccgtcc agaagtttct taccaagatg tggtggcctt catcggacca gctgcagaag
     4501 acttggatga caagattatc gaattgattg aaacagaaat caagtacgaa ggctatattt
     4561 ccaaagccat ggatcaggtt gccaagatga aacgtatgga agaaaaacgc attccagcca
     4621 atatcgactg ggatgacatc gattctattg cgacggaagc tcgtcagaag ttcaaactca
     4681 tcaatccaga aaccatcggc caagccagcc gtatttcggg agtaaaccca gcagatattt
     4741 ctattttgat ggtgtatctg gaaggtaaaa atcgtagtat ttctaaaact cttcaaaaat
     4801 caaaatgata cgtcgtcggc ttcttacgaa tgagttcaaa gcttggcttt gattcatctc
     4861 caacctccca tagttccccg aactatggga gctaactcaa gttatgcatt ttcctagcct
     4921 tctggtctga ttttcattga gttttaatct caaaagaaag catagagaaa aacagctccg
     4981 aagacggggc tgttttcttg ctttattctt catctggtgt gaggatcatc gggatgatga
     5041 tcggttcacg ttcggtattt tcatagagga aggggcgaat agcgttgaca atggcaccat
     5101 tgacagattg cacgctagca tccttatttt tcagtgcgat acgaatggca ttgaagagga
     5161 tacgctggct ttggcgaatc aagtcgccag actctctcat gtagacaaag cctcggctga
     5221 ggatgtctgg accagataga atcatctgcg atttgaagtc aacagttgcg actgccagaa
     5281 cgacaccgtc ttcagataga tcgcgacgat ctttgaggac agctgcgcca atttcaccga
     5341 tacgatttcc atcgacatag atatcttggg cgttgaaatg acctgcgata cgagctgagt
     5401 cagcagtaag ggcaagcaca tcgccattgc tcatgataaa gatattgtcc ttctcaacac
     5461 cagtatccac tgctagtcca gcgtggactt tttgcatgcg gtattcaccg tggacaggca
     5521 tgaagtattt tggcttaatc aagcagagca tgagtttttg ctcttgctga ccaccgtgtc
     5581 cagatgtatg gatattgttc actttaccgt ggataacttc gacaccagct tcagaaatga
     5641 tgttaatcag cttgttgacg ctagtagtgt ttccagggat gggactagaa gagaagataa
     5701 cggtatcacc tggttgtaat tgtacttgac ggtgggttcc gttggcgata cgagagaggg
     5761 ctgccatagg ctcaccctga ctacctgtac agaggataag aacttctcct gcaggataat
     5821 ctttgatttc atttggctcg ataaaggttc ccttaggagc tttgatgtag ccaagatcga
     5881 ttccgttgac aatggccttt tccatagaac gaccaaagac cgcaatcttg cgtccagtct
     5941 taacagcagc ttctgttgcc tgctggagac ggaagatatt tgaggcaaag gatgcaaaga
     6001 tgatacgtcc ttcaatacct tggataatct tcataatgga ctgaccaacg actttttcag
     6061 agttggtaaa ggttggtact tccgcatttg tcgagtcaga caggagacag agcacgcctt
     6121 cttcaccaag cgcagccata cgatgcaagt ccgcaggttc tccaactgga gtaaagtcga
     6181 acttaaagtc acccgtacag acgattttcc cttgaggagt atgaatgaca atccccaaag
     6241 gctctggaat agagtgagtc gttctaaaga aagttgcctt gagattttta aaggtcaact
     6301 cggtgttgtg gttgatttcg taaagtttgg cgttgcgcaa gaggccgtgt tcttcgagtt
     6361 tcccacggat caaagccaag gcaagcggtc cagcataaat agggacattt gcttgcttga
     6421 gtaggaacgg aatcccacca atgtggtcct cgtgtccgtg tgtgattaaa acagccttga
     6481 cgcggtcgat attgtctacg atgtaagagt agtcaggaat gacatagtcg ataccaagca
     6541 agtcatcttc tgggaattta atcccagcat cgacgatgat aatctcgtct tggtattcaa
     6601 ttccgtaagt gtttttcccg atttctccta gaccaccgat ggcaaaaacg ccgacttctt
     6661 caggtttaag agtgtaggcc atattagaac tccgtgattt cgaaggcgcc agtttctttt
     6721 tcgtaatcga gcaatttgtc agacaagagt tcgatatatt cgatattgta ctctgggcga
     6781 ttttcttcga caagttggcg agcagtgatg cgaccctcaa gttctgagct ggcatcgatg
     6841 tctaggtaaa gcgcgcgtgt tgtttcacgg cgtgggctac gttcttttgt ttcttgataa
     6901 aaaactttgt aaatcatata gttcctttct atttacaggt cagcttattc caaactttta
     6961 gcagatattt gcttgatttc attccatttt gtgtctagat tgaccttgat tcgttacaat
     7021 tatttcaatt ataccacaaa atgaaaaatt agtaaaagac ggaaacgaga aagttagggg
     7081 gcgatttctt tggtaatcgt ttgcaaaaat aaagaaaatg tgttatgttg ataacggaag
     7141 tgaagtttat tacttgtcat aattccatat agattttaag tcaaggaggt tgccctatgt
     7201 ataacttatt tgcttttgct atcggagttc gtttgctagc ttttatcgtt tttgttgctt
     7261 gcgtttatgg aggaaatctt ctatttgcca aactggaacg atgacaaacc aagttcttgt
     7321 ggaaaattac ctttgtgact ctctactcgc tttttctcct cctcgtgacc tatgtcgttt
     7381 ggtttgtatt ttactttgga ttaaatgctt agatgccctg cttatgctgg ttttttttgt
     7441 ttgggaatgt agagatagta gatttacgac acgaaaattc caccccatct atcaagatga
     7501 ggtggtcttt gcatttttct aacatgacat gacaatggaa ttttcaaagc ttattatttt
     7561 tatgggagtc attgttctac tcaaaaatag agttgaagca taaaaataaa acaatacaaa
     7621 cagataaatc gaatggtaaa gggatggtag taatgttcaa atcattgaga atgctgagca
     7681 aactgtaaga gatgaagaca ataaaattta tccttctaaa aatgtgtttc ttatctagca
     7741 tgacttacca aactttttac gaaggtcttt tccaatggta taacctgcca taaataaagc
     7801 gataccaaca ccgacaccaa agccaccctt gatttcttgc aattccttat tagaaatttc
     7861 acgataattg ttcaaatctt tcatcatatt aatctcctcc taaaaaataa ccagctgcca
     7921 aaccagaacc tataagtgct gttccacctg caatagcctt ccaagatact gctactccaa
     7981 agataaccaa gggagcgaga ccgccatcaa tatctgataa ttcattttca gataaggata
     8041 aaaattgatt gtcaagaatg tcaaaatttg tcattgaact ttcctccttt tttcttgttc
     8101 acttttatat tcggaaaaga aaaggaaaag tgagcatttt tttaaattat ttttagttaa
     8161 gtgagggcac tcttgtctgg gggcaaagaa aattcccatg tgccagcttt tgtagtataa
     8221 tagtaagcag acaaaaagat aggaatgtgt tatgaaagta ttagcttttg atacgtccag
     8281 caaggctctt tctctggcta ttttagagga taagcaggtt cttgccgaga cgacgattaa
     8341 tattaagaaa aatcacagta ttactcttat gcctgccatc gattttttga tggcaagttt
     8401 ggattggaca cccaaggatt tggaccgaat cgtggtagct gaagggccgg gtagctatac
     8461 aggcttgcga attgcggtag caactgctaa gaccttagct tacaccctga acattgagtt
     8521 ggttggtatg tctagtctct tggctctagt gccatatcaa caagaaggtt tgtttgttcc
     8581 tttgatggat gcgcgtcgca ataatgttta tgcaggattt tatgaaaatg ccaaacctgt
     8641 catggcagaa gcacatctgc cttttgagcg agtcattgag ctaatcaagg gcgctagtca
     8701 ggtaaccttt gtcggagaag ttggcccctt tgttgagcag attcaaaaac acttgccaag
     8761 gactgattac aaagaaacat tgcccaatgc agctaatcta gctcttttgg cctgggacaa
     8821 ggaagcagac tccttgcatg attttgtgcc aaattacctc aaacgtgttg aggcagagga
     8881 aaactggctc aagaaccata ccgagtctgg tgagtcttac attaaacgcc tatgatagaa
     8941 atcaaacgta tccaacagca acctgccttg gctcaagata tctacgctgt catggcagct
     9001 gtttacccag tcagtccttg gacactagaa caaatccaag cagatctgtc ccaagaccag
     9061 acttggtatg ctctggccta tgatggggca gaagtgattg gctttctaac tgttcaggag
     9121 actctctttg aagcagaagt cctgcaaatc gctgtcaaag gagcctgtca gggtcaggga
     9181 attgcgtcag ccttgtttgc tcaattgccg acagacaagg aaattttcct cgaagttaga
     9241 cagtcaaatc aacgagcgca agcattttac aagaaagaaa aaatggcggt catcgctgag
     9301 cgaaaagcct actaccatga cccagtcgag gacgccatta tcatgaagag agaaatagat
     9361 gaaggataga tatattttag catttgagac atcctgtgat gagaccagtg ttgccgtctt
     9421 gaaaaacgac gatgagctct tgtccaatgt cattgctagt caaattgaga gtcacaaacg
     9481 ttttgggggc gtagtgccag aagtagccag tcgtcaccat gtcgaggtca ttacagcctg
     9541 tatcgaggag gcgctagcag aagcagggat tacagaagag gacgtgacag ctgtggcggt
     9601 tacctatgga ccgggcttgg tcggagcctt actagttggt ttgtcagctg ccaaggcctt
     9661 tgcttgggca catggacttc cgctgattcc cgttaaccac atggctggcc atctcatggc
     9721 ggctcaaagt gtggaacctt tggagtttcc cttgctagcc ctcttggtta gcggtgggca
     9781 cacagagttg gtttatgttt cggaggcagg agattataag attgttgggg aaacccgtga
     9841 tgatgcggtt ggtgaggctt atgataaggt cggccgtgtc atgggcttga cctatcctgc
     9901 aggtcgtgag attgacgagc tggctcatca ggggcaggat atttatgatt tcccccgtgc
     9961 catgattaag gaagataatc tggagttctc cttctcaggt ttgaaatctg cctttatcaa
    10021 tctttatcac aatgccgagc aaaagggaga aagcctgtct acagaagatt tgtgtgcttc
    10081 cttccaagca gcagttatgg acattctcat ggcaaaaacc aagaaggctt tggagaaata
    10141 tcctgttaaa accctggttg tggcaggtgg tgtggcagcc aataaaggtc tcagagaacg
    10201 cctagcagcc gaaatcacag atgtcaaggt tatcatcccc cctctgcgac tctgcggaga
    10261 caatgcaggt atgattgcct atgccagcgt cagcgagtgg aacaaagaaa acttcgcagg
    10321 ctgggacctc aatgccaaac caagtcttgc ctttgatacc atggaataaa gagtggctct
    10381 ttgtcaagtg tagtgggtag gcgaaaagct acaatctgga gagtacgaaa ttcgtactct
    10441 cttttttgat gttcaaagtc atcaaaatcc gttttttaaa attgttaaag ttccggaaac
    10501 caaaggcttt gcgcttgata atcttaatca aattattggt cgcttcaagt ttagcgttgg
    10561 aataaggcag cttaagtgcg ttgataatct tatctctatc ccttaaaaaa gtccaaaaga
    10621 ccgtttgaaa aagcggatga accgttggca gttcttgctc aatcaatcca aagaaatggt
    10681 cggcattctt ctcttgaaaa tgaaagagca ggagttgata gagttcgtag tgaacctgta
    10741 atccctcaga gtaagaaagc agcttatctc gtacttcccg atgggttaag tgcattcgaa
    10801 acgtgggctg atagaatcgt ttctgacaga gcttgaagct atactggtgt agtaaatcag
    10861 tccagtggac tgatttagcc cgagcctaga aacgaaaaag cgagggttcc aaaagcgctt
    10921 gagcgcccga tactccaagg attttcggtc aaattggttc atgatttgga ttcgtactcg
    10981 gttcatagct cggctcagat gttggacaat gtggaagcgg tcaagaacaa tcttcgcctt
    11041 tggaaagagt tgcttagcga gccgataata agggctgtac atgtccatgg tgatgacctc
    11101 gaccagctcc cgaacctctc tctgatagcg ttggaaatgg tttcgaatca ccgcatgagt
    11161 tcgcccgtct aaaattgcga ggatggattt ggactcaaaa tcttgggcaa tgaagctcat
    11221 tttgctcttt ttgaagctat actcatccca actcataact tttggcaact tggtccaatc
    11281 ggtttcaaac ttaaattccc tcagttttcg gatgacggtg gaagttgaga ccgccaatct
    11341 gtgggcaatc tcagtcatag actgcttttc aaggaggagc tgagcgattt tttgtctcac
    11401 catgttggaa atctggcaat ttttcttgac aatggatgtt tgagaaacga ccaccttaag
    11461 gcaattcttg cactgaaagc ggcgcttttt gagatgcagt accgtgggta aaccctgaca
    11521 gtcgagaagc ggaattttag aggctttctg gaagtcgtat ttgatcatct tcccttgaca
    11581 atgaggacaa ggaggagcgg gggaatccaa ctttgcctga acgactagat gggtttggta
    11641 tttcagaaca gacaagattt tgatattttt gtcttccaat ccgagcaaat ctgtggtatt
    11701 cttaagttgt tccatatgaa ccctttctaa tgagttggtt agacgctttt cattataggt
    11761 catatggggc tttttttcta caagaaacga ccctataatt cctggggtgg gattacccac
    11821 tacagaaatt atagagccaa agcattccaa agtcttgtct gactctggaa tgttttctgt
    11881 tcacagttgt tttgtaactg cctaataagt aaccgcgcta taacgaggta tctaccgaga
    11941 ttgtcaattc tccagtatac tgttataaaa aacaaaactg gaggattttt ttatgtcccc
    12001 ccatcgtccc atcgactgtt ccgtagctgc ccaataacgg agtatagtcg gctgaaacaa
    12061 gaataggaca aaagtgcctc aagaaaagca tcgtaatttg acaatattat tctgagatgt
    12121 ttttgatgta agcccatatt ttctcaatgg gattatactc gggtgaatag gtaggaagtg
    12181 gtaacagtct atgccctgct ccttacacat gttcattctg tgaaaccttg catggtccat
    12241 aatgataagg gatggtgtat ctaaagtagg tagtaagaat ttttggaagc aagcttcgaa
    12301 aaagtcactc gtcatcgtat ctttataggt catcggagcc atagtatatt gaaacaaaaa
    12361 agggcattag tacttctata acagtatcgc aatctctggt gtgcgttgtc tcgatcttaa
    12421 ttcaaataat tatatcttct tccagagaga ctaactgcct gctcaaggct cgatcatatt
    12481 cgagataaaa ataggtctca acccctgtct cataaatata aataggagtc aggtagctta
    12541 agtgattcaa ttctttaagg aaccgattta ctttttctgg gtcttgttcg cagtaggtac
    12601 ggctcttttt tagactatat cccatagcct ttagagcgta atgaatagtt gttggaggac
    12661 agttgaattc agcagctatt tcagtcaaat aagcatcggg atgagtttca atatagattt
    12721 ttaatttatc tctatcaatt ttttcaatta atagtggaag ttttcttgaa gttagtgtat
    12781 tgaaacgttt ttatacagtg ctaaaatttg aagtgtagtg cagatggatt tgtaatagta
    12841 ttatagcaat tctttggaga aggtcgagac aagataaaat aggtatcttt gagatataag
    12901 catgatttac tataaaatta ttgagttatt cataaaaatt tctctatcaa atatcataat
    12961 gcgtcgttta aggagatggt tacaatgcaa tatagttgtg gaaaaataaa tattaatatc
    13021 cctgatggat atggagacat taaggatata gtgttttcgg ctcatattat agttaggtat
    13081 aataatggac attgtggagg tatagatccg catataattg gactttgtaa aaagcagatc
    13141 agaaggatgt ctctatatcc tattttgata atcgtatcta gagattcaaa ggttattgat
    13201 gattataaaa atttagatat tgcctatgtt gattgtactc aatgttcaaa taattttgaa
    13261 actgccttac acgttaaaaa tattttaaaa ttattaaaaa tccaacttat acactgtcat
    13321 ggctactcaa ctaattattt tttatatatg ttaaaaaaac ttgacaagaa tggatttgga
    13381 aaggttaaga cagtgataac atgccatgga tgggttgaat ataacttaaa aaagaaattc
    13441 ttgacttatt ttgatttttg gacatattct atgggagatg cttttatttg tgtatctgaa
    13501 actatgaaaa aaagattgga gagtataata aaaaaataag aagatagttg caataaataa
    13561 cggaattaat gtatcaaata gcgatttaga tgtagtaggt gttcaagact ttaaaaaaga
    13621 attttgtatt ccaaataaca aaaaaatcat ttgttatgtt ggaaggttgg atccagaaaa
    13681 aaggccggat agattccttg aatttgcaga aaaattattt ttagtcagag aagatgtgat
    13741 ttttattatg gctggaaatg gtagtatgtg ggctgctttg aaagaaaaaa tttgccattt
    13801 gaaatgtaga gataatttca ggttacttgg tgaaatctat ccagctacta tagtttacca
    13861 aatatcggat ttattgtata ttccttctga tacagaagga atacctatgt gtgttttaga
    13921 gtcaatgtca caaggaactc cggttttagc tagtaatgtt ggcgggttaa gtgaaattat
    13981 tgaacatagg gttgatggat ttttatttga gaaggaagat gttgagggag tgtgtgcttg
    14041 tgctaatttt ttactcaatg attctgagta tttgaaatat ataggtgaga atagtaaatc
    14101 aaaaataaga aaacatgaga gtatatgatg aattattaga gaagagtagt catggatagg
    14161 aatatagatc aagaattagt aagtattata ataccaacac ataataggta tgaatctctg
    14221 attagagctg tgaaaagttg tttacatcaa agttataaaa atatcgaagt tataattatt
    14281 gatgataatt atagtaatgt aaatttaaga aataaaatta tccatcaatt tggctatacc
    14341 aatcatagaa ttaagttaat tttaagtaat gaagatttag gtgcaactaa tgccagaaac
    14401 ataggtatca aaaattctag aggtaagtat atatcatttt tagacgatga tgatgaatat
    14461 atgccagatc gaattttaaa gttgatggct tgttttaaaa agagtagaat gaagaattta
    14521 gctttagttt atagttatgg aataataatt tatccaaatg gtacacgaga agaggagaag
    14581 accgattttg ttggaaatcc cttgtttgtt caaatggttc acaatatagc aggtacgtca
    14641 ttttggttgt gtaaaaaaga ggtgctagaa ttaattaatg gttttgagaa aatagattca
    14701 catcaggacg gtgttgtttt attaaaacta cttgctcaag gataccaaat tgatatagtg
    14761 cgagaattct tggtgaatta ctacgctcac agtaaagaaa acggtatcac tggagtgaca
    14821 caaaaaacaa ttaatgcaga tgaagaatat tataattact gtaggaaata ttttaattta
    14881 ttgagtttca acgagagaat attggttaca aagaaatatt attctttaaa cataaagcgg
    14941 ttactattaa taggagacaa atgcaaggct ttaaaagtaa tcaagaaggc aagagaagaa
    15001 aaaattttta acgaatttct ttttttgaaa tatatgttat tatatcattt tggttttttc
    15061 tattgtatat atgacaacta tgttcaatta aaatttagaa agtgagaaac tattgtgtat
    15121 actattataa aatcaaatat aaaaaaattt agtttattaa cgatatttat tgttgctggt
    15181 caattattgc taatttatgc agcaactatt aatgctctgg tgttgaatga attaattgcg
    15241 atgaatttag agcggttttt gaaattgtca atctaccaaa tgattgtctg gtgtgggata
    15301 atattccttg actgggtagt gaaaaattat caggttgaag tgatccaaga gtttaatcta
    15361 gagattcgaa atagagttgc cacagacatc tctaactcta cctatcaaga atttcatagt
    15421 aaatcatcag gaacatatct ttcgtggcta aataatgatg ttcagacttt aaatgatcag
    15481 gcttttaaac aacttttttt agtaataaaa ggaatttctg gtactatatt tgcagttgtg
    15541 actcttaatc actatcattg gtcattgact gtagccacct tgttttcatt aatgattatg
    15601 ctacttgtac caaaaatctt tgcatcgaaa atgcgagaag ttagtctaaa tttaactaac
    15661 caaaatgaag cttttttaaa atctagtgag actatattga atggatttga tgtgttagcg
    15721 tccttgaatc ttttatatgt attgcctaag aaaattaaag aagcaggaat tttattaaag
    15781 atggttatac aaagaaagac aactgtagaa acgttagcag gcgctattag cttctttctc
    15841 aatatttttt ttcagatatc tctcgttttt ttaacaggct atcttgcaat aaaaggaata
    15901 gtgaaaattg gtactattga agcaatagga gcactaacag gtgttatttt tacagcgcta
    15961 ggtgaattag gaggtcaatt atcctctatt attggtacga agcctatttt tttaaaattg
    16021 tattcaatta atccaattga gtcaaataaa atgaatgata tcgaaccaaa tgaggtgaat
    16081 agagattttc cgttatatga agcaaaaaat atttgctata agtatggaga taaagaaata
    16141 ttaaaaaact taaatttttg ttttcaacgt aatgaaaagt atttaatttt aggtgaaagt
    16201 ggaagcggga aatctacatt attaaaatta ttgaatggct ttttgagaga ttatagtgga
    16261 gaattgcgat tctgcgggga tgatataaaa aaaacctcct atttaaatat ggtttcgaat
    16321 gttctatatg tagatcaaaa agcttatttg tttgaaggta cgattagaga taatatttta
    16381 ttggaagaaa attatactga tgaagaaata ctacagtctt tagagcaagt tggtttgagt
    16441 gtaaaagatt ttcctaataa cattttagat tattatgttg gtgatgatgg gagattactg
    16501 tcaggagggc agaaacaaaa aattacttta gctagagggc taattagaaa taagaaaata
    16561 gtattaattg acgagggaac ttctgctatc gataggagaa cttcgttagc gattgaacgt
    16621 aagatattag atagagagga tttgactgtc attattgtta cccatgctcc gcatccggaa
    16681 cttaaacaat attttactaa gatatatcaa tttccaaagg attttattta agaatatagg
    16741 ggagggaaac atgagattct attgtgaagc ttatgaggta attactgaag agaaaaaagt
    16801 atcatttttt tatgtagatg agaaaccctt aaggtatctg ttatttgact atatatttct
    16861 actagttcta gctaaaaaaa aatatcccaa tcttatgaac tgcaccccaa aagttagatt
    16921 tattctgtct aacttttggg gtgcagttca ttttgcatag ttttggcatt catcctagat
    16981 atccatataa aatgtctgag attgttgaaa tgtctaaaaa aatatcagat ctaaacgata
    17041 aaaaagaatt tcacaaaaag aactgtgagt tgaggtttca agatagtgtt cttgataaca
    17101 taaatagtgt cccgggtaca actcatttat ttagttgttt aaatattcaa acattagtaa
    17161 aaattatttt atatattttt cgatacaaca gttgtatgaa aatatttaat tttagagata
    17221 aagagcttat cttttttaat aagattgtaa atgggctgat acaaaatatt gaggagaatt
    17281 tagaggatga tattgaaagg atattgaaat atttatatat atgtttattt aacgaaatat
    17341 tcattattaa gaataaggtg aatttttttg atgatgtgga atttaatcag acactaagtg
    17401 agtttttaga taaattgtag agggaatggt tatgagtaac aatactaagt atatcttttt
    17461 atctccacat ttagatgacg caattttttc ctgtggtgat tatatttcaa aattaacttc
    17521 agaaggagaa attgtacttg ttattactat attttctggt taccctttga gccaacagct
    17581 acagccctct gctaagcaat ttcataagtt gtgtaacctt gggaaatatc cgattgaaga
    17641 aaggaagaaa gaagacaggt tagcttgtga acgtctacaa tgtgatttta gacacttatc
    17701 gtactatgaa tgtctctata ggaaagatag aaatggcaat tttctatacc gtcatatcta
    17761 tagtgaatta aaaaatgagg acacattaaa gaatgatatc ataaaagagc tgttaatgca
    17821 tttagacgac aaatgtgtcg tatattgtcc gctttcactt ggtgaccatg ttgatcatgt
    17881 ttttgtgaat agtattggaa gggcgcttga atttatgcgt tataaagtaa tatattatga
    17941 ggacttccaa tatgtaagtg atagtagtat ggttggttat atgggaaaaa ctaaagaatt
    18001 aaaaatgtat caagaggaac ttgatgaaaa aaattatatt gatagaatat catcaatatt
    18061 gtgctataaa tctcagattt tgataatctg gaaatcagtt gaaaaacttt taaacaatat
    18121 taaagagttg tatttaagga atggggcagc ttattctatt agattttgga ttaagaaata
    18181 aggaagtagt tttatgaata tagcagtaat tggtttgggg catgttgggc tggcctacgc
    18241 gttactattt gcatctaaat ataaagttgt tgcatatgat atagattctg taaaaataaa
    18301 taatttaaaa aagggcattc ttccatctaa aaatgaagag cttatgaagt ttttttgcga
    18361 gaataactta aatattactt tttttgatac attttctgaa attaaaaata atattgatta
    18421 ttatattatt gcgcttccga cagattatga tgagaaaatt ggtagtttta atacatatga
    18481 aatcgaacaa acggtatcga agattctgag ggtaaaacct aatggaaaga ttatttgaaa
    18541 gtcaacagtt ccgatcggct tttcaaacaa attaaaaagg ctgtttgata caaaaaatat
    18601 catttttgtc cctgaatttt tgagagaagg ttgttctata tatgataatt tatatccaag
    18661 tcgcatagtt gttggagatg agacagttga aggaagaaaa attgcagagt tgttcctttc
    18721 gattagtact catagtactg ccaatattaa aaatgttatg ttagtttctc ctactgaagc
    18781 agaagcaatt aagctttttt ctaacacatt cttagctctc cgtgttgctt tttttaatga
    18841 actagattct tttgctgaga ggagaagttt aaatgctgaa gttgtaataa aaggtgtttg
    18901 tttagatcca agaattggaa atttttataa taatccttct tttggatttg gaggatattg
    18961 tcttcccaaa gatactaaac aattaaaaaa agaatttata gaaataaatg ccccagtgat
    19021 agaagcgatt gatatttcaa acacaaatag aaaacagttc atagttaaac aaatattgga
    19081 acgaaagcca aagatagtag gaatatataa attggggatg aaatataatt cagataatta
    19141 caaagagtca gctattttaa gtataattaa tgaactattg attgtcggta taaaaatttt
    19201 agtatatgaa ccaaatttaa acgttagtat agataacgta atttttgaaa agaattttga
    19261 actatttaca aaacaaagtg atctaattgt tgcaaataga tgggataggg gccttgaagc
    19321 ttataaagat aaagtttaca caagggggat ctggataaga gattaactat tgatattaaa
    19381 aaggcaataa tttataaaat ttgtacaaaa aaatgttaaa ttttcacatt ttcatagtat
    19441 actgtttaat agaaagtagg ttctttgtaa ccgctccatt ataaaatcct ttcactcttc
    19501 cggtatacta ttaggaaaaa cataactgga ggatattttg agctcacacc tcatcgttcc
    19561 agtggctgtt ccccaagctc gtgtactgcc caaaaaagtt agacattcta tttagaacga
    19621 ggattgagtt ctgtattgta caaggctcgg tccttttaga gtcagcttaa ggctggcttt
    19681 ttcaatcacc aaagtgtcag aatgttttga caaaactata aaaacaatga tatactatat
    19741 aaaaaatagg aggtggtgag atgatcgaga gaatggaatt gggagaattt tacaaagaac
    19801 tgcgcctggc tagaaagctc aagcagtcag atgtggcttg tgctggtcta acagcctctc
    19861 agttgtccaa gtttgaacta gggcagtcta tgttgtctgc agataagctc atattagcca
    19921 tccaagggat caatatgaat tttgatgagt ttgggcacaa gctcaacaac tatcaagaat
    19981 ctccacatat gcgatttggt agaaaggttg tggatcgctt tgcccatcaa gatatagttg
    20041 gcttagaaca actattggag gaagtcgagc aagaacagat ggcagagacc tatcgtcgtt
    20101 tgaatgccat cgtgattaaa gatgccatcc attccttaga taaaagctat ccgctagcag
    20161 aggaggatag cgagttttta accacctatc tctatgctat cgagtcttgg acctggtttg
    20221 aactctatct cttttgcaat accatgccct tcttgagcaa ccaagatttg atttttttat
    20281 caacctcttt gcttgaaaaa tctaaggaat ttaaagagtt ggtacataat agactgtata
    20341 tgaaaagtgg ctttctgaat attatatcag agctcatgga gcgcaaactt ttctcttaca
    20401 tcccaatctt tgaagccgag ttggagagta tgctccgtcc gtatgatgtt tttgagaaag
    20461 tgttgtggca gtttttaaag aaaatgagta tttttcttca aaccaaggga agcaaccaaa
    20521 aagagattga acactttatc caatctctgc aagtattaga aaatccacaa ttaatagtcc
    20581 tttttgaatt gcgtttgcag caatacaaaa agcttatcga ttagttagaa atggcaaaat
    20641 aataataatc tcagcaacga ttttcaataa tgttaaaatt tgtttcttca tatttctcca
    20701 ctcctcatta gtagtaactt tattatacca gagaagtaat caaattcacc aaaatcgcaa
    20761 atctgaaatt tctataagaa aaaatatcaa atatgcgatt ttctaaaata agccaatttt
    20821 cgtgttatac tgtacttgta aagcacttga agcaaatcct aggtcgcaga agtggtttac
    20881 aaatgaagat aattgaagga gtgtaaaaga tgttaaattt acaatttgca gaaacaatgg
    20941 aattgacaga agctgagttg caagatgtta gaggaggcaa cctcgtaaat tctatgggag
    21001 gtggtggaag aagtggtata tctggttggg gcgtcccagg aatttaccct ggttggggca
    21061 atcaagggat gagtcctaat cgtggagctt ttgattggac tatagattta gcagatggat
    21121 tgtttggccg ccgtagaaga taggctctta taggagataa taggatgaag aaaatgaaag
    21181 aagtgaaatt tcacctagca actggcttgt tgattttgac ttattacctc atttttaatg
    21241 tcacatcaga cttagatttt atggttgctt tgtctgataa tatgtactat gtgttccaag
    21301 ttttattggt acttattctg ggaactatag ctacaattgc ttttgtcaaa agtgaacatt
    21361 ggaaagagtg tggtcgtttc cagtttcgtt ggtcttacct gggtgttttc cttctttctt
    21421 ttttcttatt gttcgtgtgg gcaaatctaa caacctatat ctttcctcgt acccagaatg
    21481 gaagtacagt cgtagaagta gccaccaatt taacaggaat tagctatttt gttacgcgaa
    21541 tactttatac tagtattatc gcacctgtat cagaagaggt tgtttgtcgt ggtcttttga
    21601 tgacaagttt atctaaagtt aagagatact atcttgatgt tcttgtttcc gctgccatat
    21661 ttggcgctat gcatgttttg cagtatggtt ggataacgac agatttcata aagtattttg
    21721 gaatgggctt gatattttgt atgatgtttc gctacacccg atccatctat tgggctatag
    21781 ctctgcatgc ttcatggaat agtttcttac tcattgttac tttattggta tttggatatt
    21841 agaaaggtga tatatgaaaa agataatctc acaccgctac tttattatag tttttctact
    21901 agttattgct gaccagaagt tcagtgttct agttttacgc agcgaccttg ttactgggct
    21961 atctgacttt gcctattatc tgtcggatat gatgttgaat tttcttgtgg ttttatttgc
    22021 tcttattgct atgatttggt cggggaaatg gcagaaaatc aatagtagaa agtttaaagg
    22081 atcctatctt ttctattcct tcctagctct gcttgctttt gttgtttgga atttcgttac
    22141 cttttttctt ttcccaccta ctcgaaatga aatttcttat caacatgctg ctccgacttt
    22201 tacaggggct acagcatttt tgatgtattt tttctatcct gtgattgcag gtcccatttt
    22261 tgaagagata atccatcggg gattggtgat gacagctctg gaaaaaggaa agaaatgggg
    22321 gctagatgta cttggttctg ctattttatt tggggtctcg cacattagta atcacggttg
    22381 ggtcttgaca gactttttcg tctatatggg tggcggactt atatttgcag tcttatttag
    22441 aatgacaaag tccatttatt ggcctattgg gctgcatata gtctacaacg gcattggtca
    22501 gcttttgatg ttactgtaat tttggttgtt agtagtatcg cggtctattt ctggggaaag
    22561 attcccattt gaacttaaga aggagttgtg atgaaagtat ttcttcaaaa tagagatttt
    22621 aggcaattaa ctatcaacca gtggatttca acgcttgggg atacgatttt ttatctggcc
    22681 tttctgaatt atgtggcaga tgcgtctttt gcacctttgg cgattttact cattacgatt
    22741 tcagaaatcc ttccccaaat tttacaaatc tttctgggag ttttggcaga ttttcaacat
    22801 catcgtgtct tgaaatacac agtcattagt tttgcaaaat ttttgcttta ctctatcgtt
    22861 tctttatcac tttcagggca gtctttctcc ttgttgctag tagcatttat ttgtctgatt
    22921 aacctcttgt ctgacacatt gagttacttt tcaggagcca tgctcactcc gattttcatt
    22981 agaattattg ggcaagacca tctggcagaa gctattggat ttaaacagtc aactgttagt
    23041 ttagtgaaaa caatcagtaa tattctagga ggagtcttgc tagggattct ctccatccag
    23101 ttcatttcct tgctgaacgc tcttaccttt ttaatcgcat ttttaggtat ccttttcata
    23161 aaaactgacc tcttgaaagt agaaaaaacg attaactatc aagaaggact ctctgtaaaa
    23221 tccttttgcc agcatttgct ccaatcatcg aaattgatat ggaatatgaa taaggtgctc
    23281 ttggttttgt ttattatctc tactagtcaa gcagtgataa atgttacagt tcctgtctct
    23341 actctatttt tgaggaatca accctttttg aatttacaaa caggtcaatc tcttgccttg
    23401 ctatccactt ttgaactgtc agccctgatt gtcggaagcc ttgtaagtgg ctatctgcaa
    23461 cataccattt ccataaaaac agctctctat gcctcacttg tcatccagtt gcttcttcta
    23521 gtaggatttg ccacagttcg ttttgactgg attctcatct ttagtacctt ggatgccttt
    23581 ttcgcaggtg ttctctctcc tagattgcaa gaactcgttt ttaaacaaat acctgaggag
    23641 tcaatgggag cagttcaatc ctctatcggt gccattacgg ttgttttacc tagcttattt
    23701 acaatagctt tggtaaccat tgctactagc tttggaactc tggcagttag ctttgtttta
    23761 ttgctatttc ttctagttgc ctttgttatg cttctgaata ttcgtgaaag tatttagtgg
    23821 agaatttcta taatatatgt ttgagactgg attgccagtc tttttatgat ggtcaaaatc
    23881 aacagacttt tttctctttt ctgaatgtgt tataatagac tgaatctaaa atagtacgaa
    23941 acaattgcta aaaaatttat agaaattaat tttactttcc caatcgattt gttctcatct
    24001 tatttcaatc tgctatataa tagtccatgc tgtggctgga ttcttttcag tctacttata
    24061 ctcttcgaaa ctctcttcaa accacgtcag cttcactttg ccgtaggtat ggtt
//
LOCUS       DAVHLA010000031        23946 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVHLA010000031 DAVHLA010000000
VERSION     DAVHLA010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23946)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23946)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23946
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.031"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(1..229)
                     /locus_tag="VVO77_001446"
                     /pseudo
     CDS             complement(1..229)
                     /locus_tag="VVO77_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(291..740)
                     /locus_tag="VVO77_001447"
     CDS             complement(291..740)
                     /locus_tag="VVO77_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEU5693443.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            complement(742..1500)
                     /locus_tag="VVO77_001448"
     CDS             complement(742..1500)
                     /locus_tag="VVO77_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEU5693444.1"
                     /translation="MEESKELNTVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(1631..3610)
                     /gene="pknB"
                     /locus_tag="VVO77_001449"
     CDS             complement(1631..3610)
                     /gene="pknB"
                     /locus_tag="VVO77_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEU5693445.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKTPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPIQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSAE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(3607..4347)
                     /locus_tag="VVO77_001450"
     CDS             complement(3607..4347)
                     /locus_tag="VVO77_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEU5693446.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            complement(4362..5675)
                     /gene="rsmB"
                     /locus_tag="VVO77_001451"
     CDS             complement(4362..5675)
                     /gene="rsmB"
                     /locus_tag="VVO77_001451"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEU5693447.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANDSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(5668..6603)
                     /locus_tag="VVO77_001452"
     CDS             complement(5668..6603)
                     /locus_tag="VVO77_001452"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEU5693448.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGCDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPKEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(6616..9012)
                     /locus_tag="VVO77_001453"
     CDS             complement(6616..9012)
                     /locus_tag="VVO77_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEU5693449.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLKSQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYRHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSRSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(9078..9392)
                     /locus_tag="VVO77_001454"
     CDS             complement(9078..9392)
                     /locus_tag="VVO77_001454"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEU5693450.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(9417..10043)
                     /gene="gmk"
                     /locus_tag="VVO77_001455"
     CDS             complement(9417..10043)
                     /gene="gmk"
                     /locus_tag="VVO77_001455"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEU5693451.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(10173..11786)
                     /locus_tag="VVO77_001456"
     CDS             complement(10173..11786)
                     /locus_tag="VVO77_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEU5693452.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            complement(12055..12285)
                     /locus_tag="VVO77_001457"
     CDS             complement(12055..12285)
                     /locus_tag="VVO77_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEU5693453.1"
                     /translation="MEGVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMDKIRAGH"
     gene            complement(12523..13620)
                     /locus_tag="VVO77_001458"
     CDS             complement(12523..13620)
                     /locus_tag="VVO77_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEU5693454.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQSMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILVQARENVLPEAIHVLGFTEKGRQHLKSLKGQVNLVSRIGKEPWDA
                     MTQKADQIYQLGKPSIAEQNFGRVPIRIETN"
     gene            complement(13630..14376)
                     /locus_tag="VVO77_001459"
     CDS             complement(13630..14376)
                     /locus_tag="VVO77_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU5693455.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKEKKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFAMLWDTYEDEAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            complement(14479..14832)
                     /gene="rsfS"
                     /locus_tag="VVO77_001460"
     CDS             complement(14479..14832)
                     /gene="rsfS"
                     /locus_tag="VVO77_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEU5693456.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            complement(14845..15345)
                     /locus_tag="VVO77_001461"
     CDS             complement(14845..15345)
                     /locus_tag="VVO77_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEU5693457.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLGKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            complement(15346..15939)
                     /gene="yqeK"
                     /locus_tag="VVO77_001462"
     CDS             complement(15346..15939)
                     /gene="yqeK"
                     /locus_tag="VVO77_001462"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEU5693458.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLALIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            complement(15939..16568)
                     /locus_tag="VVO77_001463"
     CDS             complement(15939..16568)
                     /locus_tag="VVO77_001463"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEU5693459.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVAYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GTSYPVIWVDVPLMDISSSMVRDFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            complement(16620..16931)
                     /gene="yhbY"
                     /locus_tag="VVO77_001464"
     CDS             complement(16620..16931)
                     /gene="yhbY"
                     /locus_tag="VVO77_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEU5693460.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            complement(17145..18251)
                     /gene="yqeH"
                     /locus_tag="VVO77_001465"
     CDS             complement(17145..18251)
                     /gene="yqeH"
                     /locus_tag="VVO77_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEU5693461.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPSLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            complement(18254..18844)
                     /locus_tag="VVO77_001466"
     CDS             complement(18254..18844)
                     /locus_tag="VVO77_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEU5693462.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            complement(18796..19704)
                     /locus_tag="VVO77_001467"
     CDS             complement(18796..19704)
                     /locus_tag="VVO77_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEU5693463.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            complement(19761..20321)
                     /locus_tag="VVO77_001468"
     CDS             complement(19761..20321)
                     /locus_tag="VVO77_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HEU5693464.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQVLHFVPNRNITVVSNFSRTD"
     gene            20460..21671
                     /gene="sstT"
                     /locus_tag="VVO77_001469"
                     /pseudo
     CDS             20460..21671
                     /gene="sstT"
                     /locus_tag="VVO77_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012962425.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            21739..22692
                     /locus_tag="VVO77_001470"
     CDS             21739..22692
                     /locus_tag="VVO77_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEU5693465.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            22835..23215
                     /locus_tag="VVO77_001471"
     CDS             22835..23215
                     /locus_tag="VVO77_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU5693466.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            23314..23535
                     /locus_tag="VVO77_001472"
     CDS             23314..23535
                     /locus_tag="VVO77_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEU5693467.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            23552..23866
                     /gene="trxA"
                     /locus_tag="VVO77_001473"
     CDS             23552..23866
                     /gene="trxA"
                     /locus_tag="VVO77_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEU5693468.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
BASE COUNT         6495 a         5595 c         4735 g         7121 t
ORIGIN      
        1 ggcatttctt tttaccagaa tcattcgcta attctttttt agggcgattg atttgtactt
       61 ccgtcgcatc aatcattacc gtgtcctcag aactgagagg agttcttgaa atcgtaaaac
      121 cactttgaac aagagttact tcaacccatt ggctccgacg gattaagttg ctttcgtgga
      181 taccaaaatc agccgcaatt tcttcataag tgcggtattc tcgcacatat agaaagcgtt
      241 gttaatttat ttatctcatt tttcagaaaa ttctttcatt tgtgtaaagt ctacgatact
      301 cgatgtgttt ttatataatg atacagtctg agaatcactg ttccgctagc cattccaata
      361 gagattacca aagccaacat gacaaccaag gtcgcacttg ccagtgcttt attatagtcc
      421 cctgtcacaa aaaaggcagt tgttcggtag gagagataac ctggaaccag cggtgccaaa
      481 atggccaaga taaagaccac agcaggtgtc ttataaagaa tacttaaaat ctggctgaca
      541 caagaaccaa taatggctgc aatgaaggta gctacaatga cattggtcgg ctccttgagc
      601 aagagataga ttagccagac agtcatgccc aaaatccctc caggtaagag catagaccgt
      661 tgcacattga gtacgattaa aaaagtgata atggcaagaa aacttgctac tgcttgtaat
      721 aaaaaggttg ttagtgtcat attagttcat caataccaag gcgacagaag ttcctgcccc
      781 taaagcgagg gtaatgagca gggattcaaa catcttactc ataccagagt ttatgtggtt
      841 ggtcataata tcacggaccg cattggtcaa ggcaatacct ggtacaaacg gcatgaccgc
      901 accagctata atcaaatctg ccgttgaagg aaaacctgtg tagcgagccc aaaactgggc
      961 aattatccca aagacaaagg ctccagcaaa ggctgtcaca aagggaattc ggataaattt
     1021 ttccacatag agggaaaagg caaaaccaaa taaggtcgcc actcctgccc caagtgcgtc
     1081 gtagatattt ccgctaaaca taactgaaaa gaaaggagcg ctaaaggtcg cagccagagt
     1141 tacctgcaac ttagtatagg gaaggggttg agcttgcaag gccgtcaatt gcttaaaggc
     1201 tgtttctaaa tcaatctgcc ccccaaccag ctgacgagaa atctggttca catcgcagac
     1261 tttttcgatg ttataagaag aggaggtcac gcgcttcatg cgcgaaatat tggtattttc
     1321 aatagagaaa aagatagcgg caggcatggc aaggacattg caatccacaa tcccctgcga
     1381 atgcgcgatt cgaatcatgg tatcttctac acgatggatt tctgagccac ttttaaggag
     1441 aatagtcccc gctagcataa tcacatcaat gacggtattt aattcttttg attcttccat
     1501 gctttcctcc ttttatcaac tccctctatt ctatcacaaa tccggactca aaaaaaatct
     1561 ttgccatgaa atcatgacaa agattgatta ctcattttga ttatccatct gcttgattat
     1621 ccatctgctt ttaaggagta gctgaagttg ttttaggttt gtagattgaa atcttgactc
     1681 tagtcttatt gaggtctacc ttttcacctg ctctaggact ttgttcaaca accatgcctt
     1741 ctgcactacc tgcaggcgct gtcgtcactt ctacaacttc tatattagct tccttaatcc
     1801 caacaatttg aatcaaattg ttcttagtaa actccaagct ggaaccaatg taactcggca
     1861 tggcaacact tgtaactttt ttagctactg tcaagacaat ttgaataggt ttactcacat
     1921 cataggtcgt tccggcacct ggactttgtt tcataatcgt tcctggttcg ctttcgctgg
     1981 actcttcttc ctctatctta atcaaattct caggaacctt cttctgcttg agttctgaga
     2041 ttacttctgt agagttccgt ccaatatagt tccctaattg aatcgtcgta gcttttttag
     2101 ctactgtcaa aacaatttga gttgccttgc tcaagtcata ggtcgtacct tctggtagac
     2161 tttgcttcag gaccgttcca gcctcactct cattggactc ttcttcctca attttaatca
     2221 aattatctgg aacttttttc tcttttaatt ccgcaatgac atcagaggat ttccgaccga
     2281 cataattact aatttggaag gattgcttgc ctgatgagac aaccaaattg attttcgttc
     2341 cttcttttcg accagttcca gcgccaggat ctgtacggat aatccgccct tcttccacct
     2401 tttcactagc ctctgtcttc tcctcaccaa tctcaaaatt ggcttttttg agcgttgcct
     2461 tggcctctgc aactgtctga cctgccacat ctggaatggc aatggttgca ggagttctgg
     2521 atagtatcca aataagagaa gctgccacca atacaaggct ggccaacaaa atcaggtaac
     2581 gcatcttaaa tctatgtttt ttcggtgctt gtggttggta agtttcctct gtcacagcct
     2641 ggcttggggt tttgattgat ttgtgttctg tctgcgcttg aaccttagga atagatgtca
     2701 aggtactctg agaaaccttc ggcaaggtct tggtatctgc cttgctcgtt tcatcaaaga
     2761 ttaacttact ttcatttcta cgattgtagg acaagctact agacaagtcc acatacatct
     2821 ctgaaaccga gcggtagcga ttggtcaact ttttagcagt tgccttgata ataacatttt
     2881 ctaaagcctg aggtacagat ggattttctg caataacgga cggcaggggt ttctggaaat
     2941 gctggagggc aatggtcacc gcgctatccc cgtcataagg gatatggcct gtcaacatct
     3001 catagaaaat aatccccata gcatagatat cactctgcac agtcgccttc gaaccacgcg
     3061 cctgctctgg ggacaagtaa tgaactgagc ccaacatcga gttagtctgg gtcagacttg
     3121 tctctgcaaa ggctacagca atcccaaagt ctgtgacctt tgcagtccca tctggtgtca
     3181 aaaggatatt ttgaggtttc aagtccctgt gaacaattcc tctggtatgg gccaaacgca
     3241 tggctaggag gatttgtccc atgatacgga ctgcttcttc attagaaaga ggataatgtt
     3301 ccttgatata gcgtttgagg tctagtccag caacatactc cattgcaaga tactgttgac
     3361 cgtcttcctc accaatatct gttatccgaa cgatatgagg atggtctaga tctgccatag
     3421 ctctcgcttc acgctgaaaa cgagctacag ctatcgggtc cgtctggtag ttggtcctca
     3481 gaaccttcac tgccacttct tccccatcta agattaagtc tttggctagg tagacatccg
     3541 ccatacctcc tcgaccaatc tgtttgacaa tccgatagcg tccggcaaaa atcttgccga
     3601 tttggatcat tctgcatcct cctcgttcat agaaacaagg gcaaccgtaa tgttgtctaa
     3661 acctcctgca ttgttagcaa aacgaacaag tgtctccgtt ttatctgcta aaggaatatc
     3721 actggttaca atatcacgaa tctcactgcc tgaaatcatg ttggtcaagc cgtcactatt
     3781 gagcaagaga tagtcacctg actcaaggat aactgtccca aaatcaggct gaatttcatc
     3841 tttttgccca atagactggg tgataatatt tttttgcgga tgagcttctg cctcttctgg
     3901 tgtcaattga ccagccttga gcaattcatt aaccaaggaa tgatcgctcg tcaactgatg
     3961 gtattcttct ccacgaatca agccgatacg cgaatcacca atatgagcat agatagcctg
     4021 attatcaata atagcaagga cttccaaagt agttcccatg cctctgtaag cttcatcctg
     4081 accaagctgg tgaatctttt gattttcaat ttctaggtaa tgggcgaacc attcacgcac
     4141 ttcattgact gtatcgatct gggtatcaac ccaagctaca cccaggtctg tgaccgccat
     4201 ttcactagcg atattccctg cacgatgacc tcccatccca tcagctaaaa taatcatggt
     4261 acgtccagct ctattgacat agtggttgac atagtcttgg ttatttgttc gtttctgacc
     4321 aacatctgtt aataatgaaa tttccatgtg tcagttcctt cctaatccga tatcttgcga
     4381 aattgactga tgaagaatcc atcacttcca tacaattcag gtgtaatgag gatacagccg
     4441 tctttcatga tatccttaca ttcatgttct agttttacct gctcgaactc gggatgactc
     4501 tctaaaaagg ccttaacgac ttgaaaattc tcctctgaga cgatagtgca ggtgctataa
     4561 gttattatac cacctttgcc tagtatttga caaacactac ctaatatttc taactgaatt
     4621 tcctgcaagg acgcgaaatc tgccgtttct ttattgtatt tgatatctgg ttttcggcgc
     4681 aaaagaccga ttcctgaaca aggagcatcc accaaaatct tatcaaagga atcctggtca
     4741 aaaaactcat gcacctttct ggcatccaat ttttgagttt gaacccgatc ttcaactccc
     4801 agacgttggg cattttcttg aattaaatcc aacttgtggt cgtacaagtc cagagcagta
     4861 acctgacctg tcgtaagata agaggctata tgggctgttt tcccacctgg cgccgcacag
     4921 gcatcaagca ctcgctcatc accttgtaaa tcaagcgtcg gagcaaccag ctgactggac
     4981 tcgtcttgga tggtaatggc tccatccgca aacaaattat gccctgcaaa atgcccctgc
     5041 tccttaacca gaccagtggt tgctaaaagg gaatcattcg cctccaacaa ggcttggatt
     5101 tcctcttttc gacttaggtc tgttacacga atactggctt tgtttcgcac taacaggctt
     5161 tcaaagatgg cttttgctct ctcctctccg tattcttcct tgagtttggc aactagccaa
     5221 actgggagag aataggcaat ggagtcacgc ttgttttttc gcttgatgct agcaatatct
     5281 ggccagcctt cacgcaagat acggcgaagg acagcgttga ccaatttttc actgcctttt
     5341 ttacggagtt tggctaattc cactgcttca ttgaccacag catgatctgg aattttgtcc
     5401 aaatagcgga gttggtaggc actcatgaga agaaggacat agagccagct gtctaactgg
     5461 tctctgtctt cgataaagtg ggataggtac cattccagag tcagtttacg ggctaccgtt
     5521 ccatagacta gctcggtcac taagcccttg tctgctgcag agagctgact ccccttgagg
     5581 tgtttattta aggcaatatt tgaatatgct tgattcacaa aaacatcctc tagcactgct
     5641 agagctaaac ttctagccgt ttctacttta gtcaccaaat cgttctccta cagtcaatgt
     5701 acgtccaact ccattgagga aggaagcaat gtccatctta ggcttaccag ctggctgcac
     5761 ttgtttgagg gatagagccc cttcagccgt tgcgacaatc aattctttct tgccgataga
     5821 gagaatctca cctggatttc cctgaccttc tactggtagg gcttcataaa tcttaaagcg
     5881 gtcgccctta aggaaagtat gggcaacagg ccaggggttc attccacgaa tttggttaaa
     5941 gagttgacga ttggttttgt tccagtccag tttttcttcc tttggcttta tatttggaga
     6001 gaaggtaacc tgactcgtat cctgcggttc aggtttgata tcaccagcaa tataggcagg
     6061 cagagtgtcc aaaagcaaat cacaaccaac tagcgccaat ttttcaaaca aggtgccaac
     6121 attgtcctca tctgtgatcg gaatgctgcg acgagaaatc atatctcctg catccatttc
     6181 cttaaccatt tccatgatgg tcacaccagc ttcctcatcc ccttgaatca aggcataatg
     6241 gataggcgca ccaccacggt gtctaggaag gagggaggca tgaacgttga cagcaaagtc
     6301 catgctatca aggagtttgc ttgggagaaa ctgcccaaaa gcagcagtca caattccatc
     6361 tgctcctagc ttcataagat cttccatctc tggacttcca gataattttt caggttggta
     6421 gatagatagt cctgcttcct tggcagcctg cttgactggg gtttcttgga taactttttt
     6481 acgaccaaca gcacggtctg gctgggtcac aacggctaga atttcgtaac ggtcatctgt
     6541 caaaagtcct tttaagactg ttgctgaaaa gtcgggggtc cccataaaga ttagttttgt
     6601 catatcttct ccttcttata aaaattgctg cggctcatgg tcaatgctga gacggagctc
     6661 actattttcc cgttcttgag tcaaggccaa gacctggttg agggtcggcc ccagctcatc
     6721 ttctaaacgg tatttaatta aaatctggta atgatagagg ttgtgggtac gggcaatcgg
     6781 ttttggcgtt ggccccagaa tgggactggt ctctgacaag cctgaccgca aaatgttcat
     6841 gacttcatag gcacgtttga aaacctcttc ttctttcttg tgagaaaggg taataccaat
     6901 cgtgaaatag taaggtggat agccgagttg tcgtctgatt cccatttcat aggcataaaa
     6961 gccttcgtaa tcttgatcct tggcaaatcg aatagcatag tgctgcgaat tgtaggactg
     7021 tatcaagact tgacctgctt tttcagcccg acctgctcga cctgccacct gagtcaagag
     7081 ctggaaggtt ctctcagaag aacggaaatc aggcagattc aaggccgtat ccgcatttag
     7141 aactccgact agggtaacat tgggaaaatc caaacccttt gcaatcatct gagtaccaag
     7201 taaaatatcc gcttcccctc gcccaaactg gtcaagcaag gcttggtgac tgcctttctt
     7261 tcgagtcgta tccacatcca tcctcaaaat gcgagcttgg ggaaagagtt ctgctagctc
     7321 atcataagcc ttctgagttc ccgtcccata gtaacgaata ctgcggctct tacagttagg
     7381 acagacctga ggaatatcct tcgagaaacc acaataatgg cagttcatag tcttggtatc
     7441 catatgcaag gtcagagaaa tatcgcagtt gggacaagta tccaccgtcc cacactcccg
     7501 acacatgaca aagctagaat aaccacggcg attgagcatg agaaccacct gctctttttt
     7561 aaccagacgg tcttggatag cctctagcaa aggaggcgta aagtttgacg tctcattttg
     7621 tccgatatag tctcgaaagt caatcacttg aacctcaggg attgtagcca aaggattggc
     7681 acgttgggtt agacgtaagt gtcgatagac gcctttgcca gcacgtgccc ggctctctaa
     7741 gctcggcgtt gcagatccaa gtaccagagt tgcttgatta tactgagccc gtaaaatagc
     7801 tacctctctg gcatggtaac ggggattgct gtcctgctta taagccgctt catgctcttc
     7861 atcaataatc atgacaccca gatttttcag aggagcaaag atagcagatc tggcaccaac
     7921 aacaacttgg gcatcgccac gctccacctt acgccattca tcatactttt cgccattgga
     7981 taatcctgag tgaagaatgg ctaccttgtc cccaaaacgt gctataaaac gctcggtcat
     8041 ctgaggagtc aaggaaatct caggtaccag caaaatagct gtcttaccct tatccagggc
     8101 accttggata atctgcaagt aaacctcggt cttcccactt cctgtaatcc cttgaagtag
     8161 aaagggaggt tgagaactgc caatagaact cacaaccgca tcacgcgcct gtctttgttc
     8221 tggatttaac tccaaaggtc tacttgcttc aattccttca aaataagcag ccgagcgttg
     8281 aacttccttt tggactatgg taacagcacc ttgatccaca aagaagttga cttgctctcg
     8341 cgagtaggac tctaacaagc tagccaagga agcgctctct ggatgagaca gcagataatc
     8401 tctcagttcc aactttttct tggcacgtgt agaaatctca acaccttcta attgggcatg
     8461 gtcaacctca taccaagact gggtcttgac cttcttttga tcgactgcct gatattccag
     8521 accaagcagg ccttttctag tcaaacgcat catttcagct tgcttggcaa ggtctagtga
     8581 agaaaaggct agcgaatctt ctgaaccaaa caggcgtact cgttcttcct gactcaagcc
     8641 ttccagagga tagagaatct tgtcatagct agaattcaga aaccctggaa gcatggcctt
     8701 gaggatagag attttgtagg agaagacaga tttgcgtaac tcctcagcca gccagagttg
     8761 ttctggcgtg agaacaggag aaaaatccag cacctctgca atatctttta aatcttgctc
     8821 catctcttct ccatctgatt gggacttcaa accaagaaca atcccttgaa tcaggcgatt
     8881 ccccttacca aaaggcacat gaacccgcat cccaacttcc agcattccct caaattcctc
     8941 cggaatcctg taactatagg gctggtccgt ctgcatcaag ggcacatcta cgataatctt
     9001 agctagggcc atcttctcac ctcctccttg tcagtacatt cttgcaatag aaaaaataag
     9061 attgagtccc cccaacctta aattttttca ccatcttctt tttctttagc aatttgctct
     9121 ttgattttct tttcttcttc ttctttgcgg cgtttttctt cttcgatacg gcgacgcact
     9181 gcttcacgtt ttccttctgg atctgggtga attgtaacgt ttcctgattc gatttcttct
     9241 aaagcgcgaa gagttgattt ttcagacttg aaaccttgag ttgctggggc acctgcttcc
     9301 aattcgtggg cacgttttgc ttccaagatt acgagtgaat attttgaagg aaccttgtcg
     9361 agcaaggtat caatagaggg ttttaacatc atttgcttgt acctattttc taaattttat
     9421 cgggtagttg gagattttgg taacatctcc tgatagtgac caatgacacg atccacacag
     9481 aagtgttctg cttcaatcac acatttgaca cgttcagcag ctaggggcac ctgatcgttg
     9541 acaatcgcat aatcatactc acgcatgagg gcaatttctt ccttggcctt ttcgattcgt
     9601 tgggcaatca cttctgcact atctgttcca cgacctacca agcgatcttg caattcatcc
     9661 aaatctggtg gtgtcaggaa gataaagaca gcatctggaa cctttttctt gacctgaaga
     9721 gcaccctgaa cttcaatttc aaggaaaaca tcgattccct tgtccaaggt ttcattgaca
     9781 taggtcagag gagttccata gtagttgccg acatattctg cgtattccaa catctgtcct
     9841 tgacgaatca gctcttcaaa ttcttcacga gtacggaaga aatagtcaac accgtccact
     9901 tctccaggac gttgtgcgcg tgtcgtcatc gatacagaat attgaaattg gttttcagaa
     9961 ctctcaaaaa tctctcttct aaccgttcct tttccaaccc ctgaaggacc agaaaaaacg
    10021 attagtaagc ctcggtctgc cattgtgtct ccttttagtc aatctgtgaa ataacatttc
    10081 tctagaataa tggcaaaaag ccagattatc ctttacagtc tttctatcta gtgtaacaaa
    10141 aaagcagtaa tttttcaact gctctttctt atttatttag cataatctac tgcacgaagc
    10201 tcgcgaatca cggttacctt gatatttcct ggataatcga gattgttttc aattttctta
    10261 cgaactttgt gagccaagat tgtgactttg tcgtccttga tttttcctgg attgaccatg
    10321 atacgaattt cacgtcctgc ttgaagggca aagctagttt gcactccttc aaagccgtta
    10381 gcaatttctt ccaaatcatg gagacgcttg atgtagcttt caagagactc actacgagca
    10441 cctggacggg ctgcgctcaa ggcatctgct gcagcgacga taactgctat cacgctctca
    10501 gcttcaacat ctccgtggtg actagcaatc gtattcacca caactggggg ttccttgtac
    10561 ttacgggcca attccatacc gatttcaacg tggctacctt caacctcatg gtcaatggct
    10621 ttcccgatat cgtgaaggaa tccagcacga cgggcaagag ccgcattttc accaagttcg
    10681 ctcgccatga taccagccaa cttagcaacc tcaatcgaat ggcgcaaaac attttgtcca
    10741 tatgaagtac ggaactgcaa acgtcccata atcttcatca agtctggatg aaggtttggc
    10801 gcaccaattt cataggcagc agcctcaccg tattcacgaa tcttattgtc aatctcttga
    10861 cggtttttct caaccaactc ttcgatacga gctggatgta tacgaccatc tttgagcaac
    10921 atttccatag tcatacgggc aatctcacga cgaatcggat caaatcctga caaggtcacc
    10981 acttctggtg tatcgtcgat aatcacatcg acccctgtca aactttcaaa ggtacgaatg
    11041 ttacgacctt cacgaccaat aatgcgtccc ttcatagtat cgtctggcag atgaactgtt
    11101 gagtttgttg actccgctac atattcacca gcgatacgtt gcatagcttg aaccaagatg
    11161 tccttggcca ttttgtcaga acgttccttg acctcttgct cagcttcgcg aatgcgactg
    11221 gcaatctccc tggtcaagtt ttcctctgtc tgagccaaga taatatctcg tgcttctgcc
    11281 tgagacagag caccaatacg ctctagttct gcttcttttt gtctttcgac ttcctctaat
    11341 tgctcttcac gcgcatcaag gtttttcgct ctatcagaaa tactttgttc tttttgttca
    11401 agtgtttgtt ctttactcgt caaattgtcg tccttacggt caaggctagt agctctctct
    11461 gtcaaacgac tttcgatttg tttgagttct tgacgttctg atttgaattc agcgtccact
    11521 tcttcacggt attttctggc ttcttctttg gcctccaata gtgcttcttt tttaagagac
    11581 ttgctttcac gtttggcttc attaacaagt aaatccgctt cacgctcagc ttgtccacgt
    11641 aaattagttg cttcttgttc agcatttaaa agcatcaact ctgcagcttc ctgagatgat
    11701 ttcatcttag ctgagatgct gacatatcca atgactaaac caatgatgac ggcaaaaaca
    11761 gcaatcgcaa gcgacatgat ttccatgttt ttacctcatt ttattgttat tccgaatgac
    11821 atacattctt ttacattcta ccataaaaaa gtgattttca caaacctaaa atagaatatg
    11881 ttttggggaa tttggaacac atttaccaaa ataaacttgt tgtttagaaa tagtagttta
    11941 gtagagactt gagaaaaagc ctactttgca gtagacttcc taatgattat gcaatacaag
    12001 aagtttgttt ctaacaacag caagatttca ctcaggtatt ctctgtaaat tagactagtg
    12061 tcctgcgcga attttatcca ttcctcgcaa aaccttgtct gataactcct tattttgggc
    12121 gattctcagg gtttcctgaa tactgtccca ttcgctcttt gaaagaacta caatgtcctc
    12181 atctggattt ttattgacca ccgtcaaagg ctcaaattca tcatttacct tcttcatgta
    12241 atcctttaaa tgatttcgga atgttgagta aagaactcct tccataacca tacctcgttt
    12301 tagctctttt ccactattat acacgaaaag aaagaaattg tcaggaacct gtacaagatt
    12361 ttcttttcta tctatttata ctcaatgaaa atcaaagagc aaactaggaa actagcctca
    12421 ggctgtactt gagtacggca aagcgacgtt gacgcgattt gaatttgatt ttcgaagagt
    12481 attattcgta aaaaatctca aaaagcctac cttttagtag acttagtttg tttctattct
    12541 aatcggcact cttccaaaat tttgctctgc tatacttggc tttcctagtt ggtaaatctg
    12601 gtctgctttt tgggtcatag catcccaagg ttctttgcca attcggctga ctagattgac
    12661 ctgtcctttc agagacttga gatgttgcct gcctttttca gtaaatccaa ggacatgaat
    12721 ggcttctggc aagacatttt ccctagcctg caccaaaata taggtcaata ggcgtctgac
    12781 acgcgccttg gtgtaacgtt tggtagtcac taactcgacc aattcttcca cagactgggc
    12841 tgttttaata gcttctttaa tgcgcacagc catttcttga ttgacctgat agatggtggt
    12901 taggtcggga tttgacaaga tttgatagcg gagcaaggga aaatagtctt cccagatcac
    12961 cttactggcc tgctcaaata gggcaacaga aggcataaaa cgttctaaga aatcttggtc
    13021 cttctgatgt tgacggaggg ctgtcgccga ggcaaagtcc acatctttat tcacagaatg
    13081 gtaacctgcc ccctgacgct gaatcggatg cagcttgata tttcgtcctg caaccgcctt
    13141 tgcataggcc agagcaagaa catgattggg ggtattacct gaaaaatcaa gaccagcaaa
    13201 ttccttccac atagattggg ttttctgggg ataggaaagg gaatcaggca gattttccac
    13261 aaatttctcc atctcagcac ctttctctgt gtataagtca gcgattttct gataatctcg
    13321 aacttcctct gtcccaaaaa ctagactatc aatgcccaag cgatccaaga tatccacagc
    13381 tccttgacca aagaaatcag ctgcctgaac actgactaaa aagggcaatt ccactaccaa
    13441 gtctgcgcca ttttccagcg ccatctgggc ccttgtccac ttatccacaa tagcaggctc
    13501 tccacgctgc atgaaattcc ctgacatggc aacaattttc agtccctctg cctgatccag
    13561 caggtattta tggccattat gaaaaggatt gaactccgcg ataatacctg tgatggtcat
    13621 gctaatctcc tacttctgcg ccacaaaaaa ccaacgggtg ctagtttctg ttggttcctt
    13681 atcctcaaag tctgcataga gtttgaagga cttgaatcca gcctgttcca gtaagatatc
    13741 ataggtcaag atctcatagg tcctctcctc atgtacttca tcgtggcgac taaaggaacc
    13801 gtcagcctcc ttgataaaga aagtcagctc atgcacgatg gagtgaggag cttcgtcctc
    13861 atatgtatcc caaagcatgg caaaatcttc cgcattttca tggtaggaat agccagggaa
    13921 tacttcatct gtctggtagg tcgagtgcac gtcaaagatg aaaactccct cttcattcag
    13981 cgcattgtac acgtccttaa agacgtcccc tacttccacc tcatcctgca tatagcagat
    14041 agagtccgaa taacacgtga caaaatcgta tttccctgcc ttggacaaat tcagcatatt
    14101 accttctata aaagcaatct tttgcttggc tgaagttgct ctcttctccg caatcttcaa
    14161 catatccgca ctcaagtcaa gtccagtcac atcaaaacca gcctgagaga agcgcactga
    14221 ttgaattcct gtcccacaag ccagttccaa gagtttcttt ttctccttgg tcttaggcaa
    14281 atgacgcaga gaaaaatttg tccatttgtc gtataaacta tcgtccatga ccgcatcata
    14341 gaccgccgca aaggtttcat aagtcgccat aatcatgata ctaagagctc catggtaaac
    14401 accactagcc ctttaccttt ctatcaattt ttctaaaata agcaaagaaa cccagttgac
    14461 tacaactgag ttcatcttct aagcaagagc ttctgaaata tctactgaat tcgcctcatg
    14521 ccatagcttc tctagattat aatgggcacg catttcttct gaaaagatat gcacgacaac
    14581 agcaccgagg tccagtaaga cccagcctcc agctgcatcg ccttcgacat ggctaccttt
    14641 aaagcccgct tgagctactt tttcacggat attagctgcg atagcgtcca actgacggct
    14701 attcattgag ctagtgatga caaagtagtc cgtcacacta gtcaaatctt gtacatcaag
    14761 tgcgaggata tcctccgcac gtttctcatc agccgctttc acgactagtt ctagtaattc
    14821 tttttcgttc atttaatcct ctttttagaa aatatgtttg taatctagga catctgcaaa
    14881 gcgctcctcc caaatgtcct cataaaattc attaatcgtt tctgctggaa tgtcatcccc
    14941 atcaaaggtt gtgacagcac cttctggaac aataagctga tagccatatt caaaggcaac
    15001 cttgacagag gtatccacac aatattctgt ctgcatacca cataaaacta atttttcaat
    15061 cccctgctta tccaagtatt cttttaagcc agtttctttg aaaatactgt tatacttctt
    15121 ctgaaagacc ttttcagcag gttttcgatt taaaagcgca gataactgcc aatcttctga
    15181 tgtttgagct tcagagttct caatatgttg aacatagata atttcaatat tcttgcttct
    15241 agcctggttt tgtaaataag aaatttttcc caatagactt tttgtctgga acccagtttc
    15301 tactaaaaca ttctgaacat caatgattat aaaagccgtc ttcatttagt tctctttcaa
    15361 atagtgcaca aaggcgttat aggtttcaag ggtttgggga tagatgggga atccctgatg
    15421 agctagatac tccacggtac gagctgtttc gtaggccacc gccttattga gcgatagact
    15481 tgcaatctca cgcgccacat ctactccagg aaaggctcga ttgtgctcga tatagtctgc
    15541 gacgtagatg accttatcta ggtctgtcat ttgaccagca ccgactgtat ggacttcaat
    15601 ggctcgcagg atttctgaat catgcaaatc caaatcttcc tgaattttgt aaattccgac
    15661 cataccatgc cagacattat tgccccagtt tttgaggtca gggtctagct ggtaacggtc
    15721 aatcaaggct agaaattcct gatctgacaa ctttttagca tagtcatgaa gaagacctgc
    15781 tagacttgct ttctcaacat ctacaccaaa gcgctgagct aattccatag cggcacgctc
    15841 cacacctaga caatgggtta gacgtttctc aggtagaagc tctgccattt tttccaacaa
    15901 ggcctcacgg gagcagttga tatagtcttg ataggacatc agtagagccc ctccttctcg
    15961 atgtagtcta gcactggctg aggtaggaga aagttgggtt tccgaccttg ggcaaggaag
    16021 tcccgcacca tgctggacga gatatccatg agcggtacgt ccacccagat aactggatag
    16081 gaagtcccta ccttgtagcg tggacgctga acccccacaa actgaaccat gtcaaccagt
    16141 tcatcaattc ggtaccactt aggcagatag gcaaccatgt cggcaccgat gataaagtaa
    16201 taatccgtat ctggattctt ctctgtcaaa atcttcatgg tatcgtaggt gtaggaaata
    16261 cccttgcgct ccaactcaat ggtttcaatg actaggccgt caatcccctc aattgccaac
    16321 tcaagcatct tgagacgatg gtgttcaggg atggtttcct ttttatcaac gtgaggaggt
    16381 tggtattcag gcatgagaag aacttgatcc agtcccaact gttgccgtac ttgatccgca
    16441 acaatgagat gggcattgtg aacagggtta aaattccccc ctaaaatccc aacttgtttg
    16501 cgttttttct ccttgatttc tggctccaac tctaccttgg taaagggagt caatagttcg
    16561 attgtcatag gctagtcccc tttatttctc tataaaaaca gttatttgga gtttcggtct
    16621 tagatttctt tgactttctt agaaatcttg cgattttctt tcttgctaga ttgtttaaac
    16681 aaaatcaaga tgcgtcctat tttttggact gtatccacac cgatttcttc ttccaaaatt
    16741 tcagctactt cgtggatgtt ttcatctgtg ttttgtaaga gagtaacctt gattaattca
    16801 cgcgcatcaa gagcttgacg gacgctggtt ttgatttggt cgttgagtcc atttttcccg
    16861 atttggatga taggtttgag ggtgtgtgcc tggctgttga ggaaggcacg ttgttttgat
    16921 gttaatgaca taattttctt ccttgttttt ggatagttat tttaggtggt gagggacggt
    16981 cggaactaat tttccaaaga tttcatcttt gaaaaatgga tttcctgacc tcacaattga
    17041 gccttggtct caattgtgcc ccttgccaat ctacagattg gcaatcacac cacggcaata
    17101 actatcgcta tatgagctca ctttgttcgc tcagcgattt tgttttaaat aattgctttt
    17161 cgtgtgacga cggcgacgcc ttctggtgcc cagacggcga cttttgctat gcctgttaca
    17221 cgaatccagc ctaggcctga gatgactagg tctgtcttat ctttaatggt aaagacatgc
    17281 tggactagac ttgggaaatc ttctttttcc ttgctatttg gtggtgtcag aagagttccc
    17341 aggtgcttat cgtagaaagc actagctcct tcaagcttgc tacgatggag tttgagttca
    17401 ttatcaaaga aagcagtaaa tccttgcttt tctcctgcta taaagtcaaa gcgtcccaaa
    17461 ccacctaaaa atagggtttg ctcaggatta agctgatagg tcttaggctt gatttccttt
    17521 ttaggactga catacttgag gtttttggcc gtcaagtagt gagccatctg gtggcggtgg
    17581 ataattcccg gcgtatcgta aatataagat ccgtcgtcaa gcggaatctc tattttgtcc
    17641 aaggttgtcc ctgggaagcg tgaagtagtg atgacattct gatcacccgt gatttcttgg
    17701 ataatagcat tgattagagt tgattttcca acgttggtca caccgaccac atagacatcg
    17761 cggcccttac ggtagtgttc aatcttgtca atgacttcct taatggcatg tttattttgt
    17821 gctgaagtta ggaccacatc gactggacga agaccttctt catgggcacg tttcatgagc
    17881 cactggctaa tcttaccaga cttaactgac ttaggaagga tatctttttt atttcctacc
    17941 aagaggacat cattgcccga gacgaaacgt ggtaaacctg ggatgacaga tccattaaaa
    18001 tcaaagatat caataacatt gaccactaaa gcatcactgt ctcccacctc gtgcaagagc
    18061 ttgaggaaat catcgttcgt caactggaca tctgtgattt cattgtagtg gcggagacgg
    18121 aaacagcgtt ggcaatagac ttcgccagtc tccaaacctt tttcaagtgc cgactggggg
    18181 gtaaaaccaa gaccagcttt atctgtcgtc tgaatggttg ctccacaacc aatacagaga
    18241 atttcttcca tagttaaatt ccttttttat atgtaatcgg tccgtacttt tcagtgattt
    18301 ttctcataac acgacgctca cgagttcggt taatctgcgt tttgattgag tcatgttgga
    18361 ccaagggttt gactaaaatt gaccgaatcc ctgcacggtg ggctgctcgt atatctgtca
    18421 tgagctggtc accaaccatg accacttcct ttttgtcata gtggaattcc ttcatagcac
    18481 ggtcaatacc aaatgtgaag ggcttcaagg cccagtaaac gtaatcaatc ccaaatttct
    18541 caactgctcg ttgaacgcgt tttttggtgt tatttgacac tacgataatg ccaatacccg
    18601 cgtcccgaag gtcatgtagc cattgcttca tctctggcgt tccatcaggg ttgttccaag
    18661 caatgagggt attatccaaa tcgaccaaaa cagccttgat tccctgcgcc tgcaggcttg
    18721 ggactgtcag atcatagact gcttccacag caaaatctgg tatataattt tcaatcgcca
    18781 ttctggctcc ttttcttaac tttttttcgc aattttcctt agtaacaagg ataaaacaat
    18841 ccacaaacct gcactagcca aactgatata gagccaagca tggggctcat ctgttaaagg
    18901 taagggaaca ttcattccga aaaagcctgt cacgactgcc aaaacagcta gcaagactga
    18961 aatgatagtc aaggttgtca aattgtcatt cagattattg tttagaatat tgttgtaaga
    19021 ggctgaaagc tgctgtaaaa tctgagagat taggtctgtc atggatacca gctgatgagc
    19081 ctcaatcatg gcatcatcaa actgttctct ctcaatctca tcaaaactac gatacaaggc
    19141 atgaccttga atatgctcta acaaaatccg attttgtttg gcagctgccg tcagataaac
    19201 cataccagtc tccaaatcag acagggcaaa gaggtttttc ttggtagttc gctggcgcaa
    19261 gaggtcattg acctcatccc tactcttgtc catctgctca atgacaggat agtaggcatt
    19321 gctgataatt tccagactgg caaagagaaa cttataaatc gaaagcgtgt catggctctc
    19381 cagataacga gtcatctgtt caatgacata ggcgttcttg gtattactaa tggtaatcag
    19441 gcgacgatgc tcgacaataa aggtcatggg aaaagtctca tagtaggcct tgtccttttt
    19501 tacgtctagg acattataga taaaggtaac cgtcccactt tcacggtggt agtccatgtg
    19561 ggcgcgctcg tttctatcca gtgcgtattc aatggtttcc ttgtccaaac cgtaaatttc
    19621 agaaaggtct tctagtttat tcaactttcc taggtctagg tctatccagg tacaaccatt
    19681 gcccaactgc ttttctaaaa ccatcttttc tccttattaa actccctcta ttgtaccaca
    19741 aattacttaa aataacaggt ctagtctgtg cgtgagaaat tgctaacaac tgtgatattt
    19801 cggttaggga caaagtgaag gacttgctcc tcgctacgaa gctgtgtcgt acgaattccc
    19861 acactgacaa ccttacccga tacagtaatc ggtccatttg tcagaacgac ctcatctccc
    19921 acatccagtt gacgttcaaa gaggatgaaa aagccattga tgacatcaga cagaaagcct
    19981 tgggctccca taccaatcgc taccccagca ataccagctc cagccagcaa actagaaact
    20041 ggcaaaccta aaatcgacaa aatgcagtag agtaaaaaga aatatagcgt ataattaaac
    20101 acattttcta gtaaacgtga gatggttttt tggcgtccaa catcatgacg agacattttt
    20161 agagaaggtt tgacaattct ctgcaccatg gtatgaagca tttttttagc aatataaaat
    20221 acaatcaaaa gcagtaaaag agaaatgacc ttggttagaa tattctcgat aatggttgtc
    20281 acatctagct tttcaatata agcctgaata aatttttgca tataaaactc ctttatttca
    20341 ttataccata ttttcatcag tctcattctc cataaatatt caaaaaatag acagaaaatt
    20401 cttgattttg tctatcattt atactataat cataatcact acacaaaaag gagattatta
    20461 tgaaaagaat cattcatgct tggaataagg caagccttgt caagcgtatc ttgattggta
    20521 tgctttgtgg ggaatcctag gactgaccct tcctaatctc tcagggattg ggctactcgg
    20581 ggatttattc gttggaggtc taaaagctgt tgctcctatc ctagtctttg ccctcgttgc
    20641 caatgccctt tcccaacatc aaaagggaca agatagcaat atgaaaactg ttgttttctt
    20701 gtatatccta tgatagggac tttcgccgct gctcttgtag ctgtactagc aagtttcatc
    20761 gtccctattg aaattaccct aaatagtgcc aatactgaaa ttgcaccacc agatggggtt
    20821 gggcagatcc tcagcaacct cttgctcaaa ctggttgaca gcccagtcaa cgcgccctgt
    20881 ttactgctaa ctatattgga atcttatctt gggcagtcat ttttggaatc gctatgagag
    20941 aagccagtaa aaatagtaaa gaattgctaa aaactatcgc tgacgtgact tctaaaattg
    21001 tcgaatggat catcaatctg gctccatttg gaatccttgg tcttgttttt aaaaccattt
    21061 ctgacaaggg agtcggaagc cttgccaact acggtatttt attggttcca ttagtaacga
    21121 ctatgctttt tgttgcccct gtggtcaacc ctttgattgc cttcttcttt atgagacgca
    21181 atccttactc tctagtttgg aactgcctcc gtgtcagcgg tgtgacagcc tttttcactc
    21241 gtagttctgc gactaacatt cctgtcaaca tgaaactctg ccatgacctt ggactcaacc
    21301 cagataccta ttctgtttct atcccactcg gttctactat caatatggct ggagtagcga
    21361 ttaccattaa ccttttgacc cttgctgcag ttaacactct tggaattcct gttgactttg
    21421 ccacagcctt tgtcctcagt gtggtagcag ctatctcagc ctgtggtgct tcaggtattg
    21481 ccggaggttc cctccttctt atcccagttg cttgtagcct tttcggtatt tctaacgata
    21541 ttgccataca agttgttggg gttggttttg tgattggtgt catccaagac tcatgtgaaa
    21601 cagcccttaa ttcttctaca gatgtcctct ttaccgccgt tgccgaatac gcagcaaccc
    21661 gtaaaaaata actcatcaag gcaagcctgc tcatgtcttg tcttttacgc ttttattcta
    21721 acttattagg aaattcttat gtctattagc caacgtacga ccaagctcat cttagctacc
    21781 tgtcttgcct gcctgcttgc ttattttctc aatctttcgt cagcagtttc ggctggaatt
    21841 atcgctctct tgagcctatc tgatacgcgt agaagtactt taaaactggc tcgcaatcgt
    21901 cttttttcta tgcttctagc tctggctatc ggtgttctag cttttcactt gagcggattt
    21961 catatctgga gtctcggcct ctatctggcc ttctacgttc ctttagccta caagatgggc
    22021 tgggaaattg gcatcacacc aagcacggtt ttggttagcc atctcttggt tcaagagtca
    22081 acctctccag acctcctagt caacgaattc cttctctttg ctattggtac aggatttgcc
    22141 ttgcttgtta atctctatat gccttcacga gaagaggaaa tccagcacta ccacacgctg
    22201 gtggaagaaa agttaaaaga tatcctccag cgcttcaaat actatttatc cagaggagac
    22261 ggacgcaacc gagcacagct ggtagcagaa ttagacacgc ttttgaaaga agccctcaga
    22321 ctggtctatt tggatcactc tgaccacctc tttcaccaga ccgactacca tatccactac
    22381 tttgagatga gacagcgaca aagtcgtatc ctgagaaaca tggcccaaca gattaacact
    22441 tgtcaccttg ccgccagtga aagcctgatc ttagcgcaac tcttttcaaa aattgcaggt
    22501 caactgagcc agaccaatcc tgcttctgat ttgctagatg aaattgaacg ttatctggaa
    22561 gtcttccgga accgcagtct gcccaaaaca agagaagagt ttgaaacccg cgccaccctt
    22621 cttcaactcc tacgtgaagc caaaaccttc atccaagtaa aagttgattt ttaccaaaaa
    22681 tatagacagt aaaaaataaa accactaaaa aacagagctt gccagcattc ttgaaaagta
    22741 gtataattat tgcatgcgca atcatcttgt gacgcagaga ctgcccgtta atggactttc
    22801 ttctatttat gactctaaaa agaaaggaga cactatgacc tatttggaaa aatggtttga
    22861 cttcaatcgg cgtcagaaag aaattgaaag tctcttggaa gagaccattg cccaacagag
    22921 cgagcaaagt ctgaccttga aagagttcta cctgctctac tatctggact tggctgaaga
    22981 aaaatctcta cgccagattg acctgccaga taagcttcat ctgagcccga gcgcagtttc
    23041 taggatggtg gctcgcttgg aagctaaaaa ttgcggtcta ctcagtcgca tgtgttgcca
    23101 tcaagataga cgctctagtt ttatctgcct gacaaatgat gggcaaaaga cactggcctc
    23161 gctacaaaag actgtcgaag aaagcttgga agcaggtttg gatttcttga tttaagatga
    23221 ttttaaaaaa agttgcgtgc gcaatcattt ttcttgacat tctcttttat aaggagtaaa
    23281 ataaagttag cattaaacaa aggagtttta aacatgattg aaattaccta tatagatgcc
    23341 agcaagaacg aaagaactgt gactttcgag tcttatgaag actttgaacg ttcgcaacaa
    23401 gcttgcctta tcggcgtcgc agactactac cctgtccaaa aattaactta caagggtcat
    23461 aatttggact accatgggac ttatggagat atcttcttct atctcatgaa acaagattta
    23521 agccaatata actaaaaaaa ggagaaatac aatggcaaaa gcaattacag atgcaacatt
    23581 cgaacaagaa acaaaagacg gtttggtctt agtagacttc tgggcaactt ggtgtggtcc
    23641 atgtcgtatg caaggtccaa tcttggacaa attgtctgaa gaactttcag aagatgtctt
    23701 gaaaatcgtt aaaatggacg ttgatgaaaa tccaaacaca gctcgtgctt ttggaatcat
    23761 gtctattcca actcttctct tcaaaaaaga cggccaagtt gtcaaacaag ttgcaggtgt
    23821 tcacacagca gaacaaatca aggccatcat tgctgaattg agctaatcaa acgagagacc
    23881 aagtactttc tttggtctct tttttcttgc cctttgccat ttttcaaaaa atatgctaga
    23941 ctatag
//
LOCUS       DAVHLA010000032        23222 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVHLA010000032 DAVHLA010000000
VERSION     DAVHLA010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23222)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23222)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23222
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.032"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(35..271)
                     /locus_tag="VVO77_001474"
     CDS             complement(35..271)
                     /locus_tag="VVO77_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEU5693469.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(339..1259)
                     /locus_tag="VVO77_001475"
     CDS             complement(339..1259)
                     /locus_tag="VVO77_001475"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEU5693470.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDSDSYYYRFTQMPIGEVEAFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            1449..1852
                     /locus_tag="VVO77_001476"
                     /pseudo
     CDS             1449..1852
                     /locus_tag="VVO77_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2068..2649
                     /locus_tag="VVO77_001477"
     CDS             2068..2649
                     /locus_tag="VVO77_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU5693471.1"
                     /translation="MYYAENPDAAHDIHELRVDLLGEKMTFLTDAGVFSKKMVDFGSQ
                     LLLKCLDVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLAQRNAEKNNA
                     KATIFQSNIYARVQGRFDHVISNPPIRAGKQVVHEIIEKSKDFLEIGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            2646..3923
                     /locus_tag="VVO77_001478"
     CDS             2646..3923
                     /locus_tag="VVO77_001478"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEU5693472.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLIEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDVLDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            3941..4603
                     /gene="deoC"
                     /locus_tag="VVO77_001479"
     CDS             3941..4603
                     /gene="deoC"
                     /locus_tag="VVO77_001479"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEU5693473.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVRLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            4590..4979
                     /locus_tag="VVO77_001480"
     CDS             4590..4979
                     /locus_tag="VVO77_001480"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEU5693474.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAVFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            5069..6121
                     /locus_tag="VVO77_001481"
     CDS             5069..6121
                     /locus_tag="VVO77_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEU5693475.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            6265..7800
                     /locus_tag="VVO77_001482"
     CDS             6265..7800
                     /locus_tag="VVO77_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5693476.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINMHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            7793..8851
                     /locus_tag="VVO77_001483"
     CDS             7793..8851
                     /locus_tag="VVO77_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5693477.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLTELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            8854..9810
                     /locus_tag="VVO77_001484"
     CDS             8854..9810
                     /locus_tag="VVO77_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5693478.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGVIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            9895..11243
                     /locus_tag="VVO77_001485"
                     /pseudo
     CDS             9895..11243
                     /locus_tag="VVO77_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(11288..11929)
                     /gene="plsY"
                     /locus_tag="VVO77_001486"
     CDS             complement(11288..11929)
                     /gene="plsY"
                     /locus_tag="VVO77_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEU5693479.1"
                     /translation="MITIILLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            12065..14008
                     /gene="parE"
                     /locus_tag="VVO77_001487"
     CDS             12065..14008
                     /gene="parE"
                     /locus_tag="VVO77_001487"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEU5693480.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KVGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRSDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVINTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            14428..16899
                     /gene="parC"
                     /locus_tag="VVO77_001488"
     CDS             14428..16899
                     /gene="parC"
                     /locus_tag="VVO77_001488"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEU5693481.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAATRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            17029..18051
                     /locus_tag="VVO77_001489"
     CDS             17029..18051
                     /locus_tag="VVO77_001489"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEU5693482.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGSVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            18107..18781
                     /locus_tag="VVO77_001490"
     CDS             18107..18781
                     /locus_tag="VVO77_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001828992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU5693483.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     STTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGFAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGDPYIFKGMKLQKDIVTTKEYNEVFKKWQIPK
                     RTRKIH"
     gene            18850..19539
                     /locus_tag="VVO77_001491"
     CDS             18850..19539
                     /locus_tag="VVO77_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEU5693484.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            19536..20459
                     /locus_tag="VVO77_001492"
     CDS             19536..20459
                     /locus_tag="VVO77_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEU5693485.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            20474..21118
                     /gene="pcp"
                     /locus_tag="VVO77_001493"
     CDS             20474..21118
                     /gene="pcp"
                     /locus_tag="VVO77_001493"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEU5693486.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            21286..21516
                     /locus_tag="VVO77_001494"
     CDS             21286..21516
                     /locus_tag="VVO77_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEU5693487.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            21566..21646
                     /locus_tag="VVO77_001495"
     tRNA            21566..21646
                     /locus_tag="VVO77_001495"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21600..21602,aa:Tyr,seq:gta)
     gene            21656..21727
                     /locus_tag="VVO77_001496"
     tRNA            21656..21727
                     /locus_tag="VVO77_001496"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21688..21690,aa:Gln,seq:ttg)
     gene            21889..23091
                     /gene="rpsA"
                     /locus_tag="VVO77_001497"
     CDS             21889..23091
                     /gene="rpsA"
                     /locus_tag="VVO77_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEU5693488.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFVDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
BASE COUNT         7011 a         4085 c         5283 g         6843 t
ORIGIN      
        1 ttcttcaacc cactacagtt gacaaagagc cttcttattt agcaagttta gctgaaagac
       61 gagctttatc gcggcttgct ttgtttttgt gaatcaaacc tttagtttct gctttatcga
      121 tagctgagct agcagcacgg aaaagttctt cagatgggtt tgcttcgaaa gcttttatag
      181 cagtacgcat agctgatttt tgagctgagt tcttttcgtt ttgtttaacg ttcaattcag
      241 cgcgtttgat agctgattta atgtttgcca atgttcttac ctccatattt actaactata
      301 ccattatata tgaaaactta cgttttgaca agggaaaatt atttttttaa gtaaatttca
      361 tcgatttcat ggttcttgct tttatgaaga atcacttctg cacgatttct ggttggttca
      421 atataatttt gtagatttgt gagattgata ctggtccaga cctgatgggc aaaggcttcc
      481 acttccccaa tcggcatctg agtaaaacga taatagtagc tatcagagtc gttttgggct
      541 agactcagca ttttcaagaa acggtccaga taccaacttt caatatcatc cactccagca
      601 tctacataga tggaaaagtc aaagaagtca gtgatataga gacgatcgtt ttgtggattt
      661 tgaaagacat tgattccctc aacaattaca aaatcagcag ctttgacact ttgtttctct
      721 tcgggtacga tgtcgtaaac ttcatgagaa tagacaggaa tatctacatc ttgtccattt
      781 ttgatgcggt ccaagaagtt gagaagagct tccatatcat agctttcagg aaatccttta
      841 cgatttaaaa tcccctgctc aatcaaggtt tgattgggat agagaaaacc atcagttgta
      901 accaactcaa ccgtagcatc tgtaaacgta cgggacagta ggatttgaag taggcgactg
      961 gttgtggatt ttccaacggc aacactccca gaaaccccaa taataaaagg ttgagattta
     1021 ctttcacgtt ggaggaaaat tccttttgaa aaggctaaat cttccttagt tcgcttgtaa
     1081 atctgaatca gatgagccaa ggggagatag atatctgtaa cgtcttggag actgatttgg
     1141 tcattaaaac tcttgataga ttccaattct tcttctgtca aaggaggtgt tgtctttcga
     1201 tgtaaagatt gccaagtctg gcggctgatt ttttcaaaat gtaaaaattc gttggtcatt
     1261 tgttttcccc tagatatttt gtctatcata ccataaaaag ctaaaaaaat aaagcggttt
     1321 cttgaatgtg gtaagtcaat ggtatatagt ataagtgatc aatttattga tgaaatagga
     1381 gatagattct actgatttat aagcttataa agggggcttt ttagttcaca acttatagga
     1441 ggtgtactat gaaaatctta aaacgttaca tattggaact ctgttttatt ttaagttttg
     1501 ctttaccttt tataaaagga gccaatgcag ataatggtag atgctttgtg gaaacctatt
     1561 acggttttac ttttttgatg gaacatgcta ttgtaacagc tgtctttatc tgttcgttct
     1621 taattgcttt cttactaaaa aacgatgggc gaaatggatt gctgcgggta gttattgctt
     1681 tttagtccta cggattgcga cagagggtta tttcttccac atgtcactag aagatttgat
     1741 acgactttgg acaagtttgg aaatcctgac acaaacgtat cagttgggct tttatctaaa
     1801 cattttgtta ggaattttgt tgataataaa gtattttaag gttaagcaat agaaataata
     1861 atctgcctga ttatagatga taaacttttt gtttttatct ggactgtgat atttatagtt
     1921 ctaaatggtt tattatttat aagtgttgaa agagattgaa gaaaatggct tcgtgacttg
     1981 ctttcttcgg tctttttcgt tttattatca atttgtaaac gatttacaat ttgagtcaaa
     2041 ttatggtaaa atagtgtcat gagtaaaatg tactatgcag aaaatcctga cgctgctcac
     2101 gacattcatg agttgagagt ggacttgttg ggagaaaaaa tgactttttt gacagatgcg
     2161 ggtgttttta gcaagaaaat ggttgacttt ggaagtcaac tcttgctcaa gtgtctggat
     2221 gtcaaccaag gagagacagt cctagatgta ggctgtggct atggtccatt aggtttgtcc
     2281 ttggtcaagg tttacggagt tcaggcgacc atggttgata ttaacactcg tgccctggat
     2341 ttagctcaga gaaatgctga aaaaaataat gcaaaagcga cgatatttca atctaatatt
     2401 tatgcaagag ttcaagggcg atttgaccat gtcatttcca atcctcctat ccgtgcgggc
     2461 aagcaagtcg ttcatgaaat catcgagaaa agtaaagatt tcttggaaat tggtggagat
     2521 ttgaccatcg tcatccagaa aaaacaagga gctccaagtg ccaagtctaa gatggaagat
     2581 gtgtttggca attgtgaaat ccttaaaaaa gacaagggat actatatcct tagaagtgtg
     2641 aaagaatgag agcagttgat ttaatccaaa aaaaacgaga cggtcaagaa ctgacttcaa
     2701 gtgaaattga atggctgata gaaggctatg tatcaggaac tgttcctgat tatcagatgt
     2761 ctgcctttgc tatggctgtt tattttaaag gaatgacgac tcgagaaatc tctgatttaa
     2821 cgatgaatat ggttaagact gggcaagagt ttgacctgtc agccattgat ggtgtgaaag
     2881 ttgacaagca ttctactggt ggtgtcggcg ataaggtaac cttgatttta gctcctcttg
     2941 ttgctagctt cggtgtgcct gtagcaaaaa tgagtggtcg tggtcttggc catacaggcg
     3001 gaacaattga taaattggag tccattaagg gctatcaagt agaacgtagt caagaggatt
     3061 ttattcgtca ggttcaggat attggagtat ctgtcattgg gcaatcagac cagctggtca
     3121 aagcagataa gcttctctat gcccttcgtg atgtgaccgc aactgtcgac acgattcctt
     3181 tgattgcgag ttcggtgatg agcaagaaaa ttgcggcagg ggcggatgct attttgctag
     3241 acgtgactgt cggtgagggt gccttcatga agacggttga tgaggcgcgt gagttggctc
     3301 aaactatggt agatcttggt aaggttgttg gacggaagac agtagcagtg attacggata
     3361 tgagccagcc tttgggacga gcgattggaa atcgtctgga aatccttgaa gcattggaga
     3421 ttttgcaagg tcaaggacgt caggatatta cccactttat ttgtgaattg gctcaaatta
     3481 tgcttggttt ggcaaatgtt aacaaaactg ttgaagaagt tcgccaacat cttgaaaatg
     3541 gtcaagcact ggctaagttt gaggaaatgg tgcaagccca aggtggagac ttggaagacc
     3601 tctatcgtcc tgtaaatgta gctcatgtgg tggaaatccc tgctcaggaa acgggtgtca
     3661 tttcagctct tccagctatg gactttggtc tttatgccat gaggctgggt gctggtcgtg
     3721 cagttaagtc tgatgtcttg gactatgaaa caggaattgt ttttgaaaag aagattggag
     3781 actccgttca aaagggtgaa attgttgcaa aagtatacac aaatgaaaaa attccacctc
     3841 aactagttac agatttccaa aaatgtgtta aaataagtga tgaagtgaaa aaaatccgtg
     3901 aaattgtaga aatcatctcc taaatggagg gaaaaccgaa atgaaattaa ataaatatat
     3961 agatcatacg cttttaaaac aagatgcaaa gaaaaaacaa attgatagtt tgttgtctga
     4021 ggctagagag tatgactttg ccagtgtttg cgttaatccg acctgggttg aacatgctaa
     4081 aaaaggactt gaaggcacag atgttaaggt ttgcacagta gtaggtttcc ctttgggagc
     4141 aacaacttca gccgtgaaag catttgagac aaaagaagct atccaaaatg gtgcagatga
     4201 gattgatatg gtgatcaatg ttggagctct caaatcaggt aatttagcct tggttgagtc
     4261 agatattcgc gcagtagtgg aagcaagtgg tgataagtta gtgaaagtca ttattgaagc
     4321 ttgccttctg acagaccaag aaaaaattgt tgtttgccaa ttggcccaaa aagctggggc
     4381 tgactttgtt aaaacatcta ctggcttttc aactggtggt gctacgatag cagatgttag
     4441 attaatgcgt gaaacagttg gatctgatat gggagtcaag gctgctggtg gagctcgttc
     4501 ttatgcagat gctcttgcct ttgtcgaagc aggtgcgacc cgtatcggaa cgtcagctgg
     4561 ggtagctatt ttaaaaggag aattggcaga tggcgactac tgagttgatt gaactggcaa
     4621 ttgaaaccag caaacatgcc tatgtcccct attctcactt tcctatcgga gcagttttag
     4681 tagccaaaga cggaagtgtt tacacgggag tgaatatcga aaatgctagc tatcctttga
     4741 ccaattgcgg tgagagaaca gctgttttta aggctatatc tgaaggccaa agagaatttt
     4801 cagaattgat tgtctatggt caaactgaaa aaccgatctc gccatgtggt gcttgtcgcc
     4861 aagtaatggt cgaatttttt gaacaagatt taaaagtgac cttagtcgca aaagataaat
     4921 cgacggtcga gatgacggtc ggggaattac ttccatactc ttttacagac ttaaactagt
     4981 ctgagtcgct ctctgagtgg cacggtcctt gtggccaacc aatccatact tgcaacatcg
     5041 ttgcacatct tatttaggag gttcagtaat gaacaagaaa caatggctag gccttggtct
     5101 agttgcagtg gcagcagttg gacttgctgc atgtggtaac cgctcttctc gtaacgcagc
     5161 ttcatcttct gatgtgaaga caaaagcagc aatcgtcact gatactggtg gtgttgatga
     5221 caaatcattc aaccaatcag cttgggaagg tttgcaggct tggggtaaag aacacaatct
     5281 ttcaaaagat aacggtttca cttacttcca atcaacaagt gaagctgact acgctaacaa
     5341 cttgcaacaa gcggctggaa gttacaacct aatctttggt gttggttttg cccttcataa
     5401 tgcagttgaa gaagcagcta aagaacacac tgacttgaac tatgtcttga ttgatgatgt
     5461 gattaaagac caaaagaatg ttgcgagcgt aactttcgct gataatgagt caggttacct
     5521 tgcaggtgtg gctgcagcaa aaacaactaa gacaaaacaa gttggttttg taggtggtat
     5581 cgaatctgaa gttatctctc gttttgaagc aggattcaag gctggtgttg cgtcagtaga
     5641 cccttctatc aaagtccaag ttgactacgc tggttcattt ggtgatgcag ctaaaggtaa
     5701 aacaattgca gccgcacaat acgcagccgg tgcagatatt gtttaccaag tagctggtgg
     5761 tacaggtgca ggtgtctttg cagaggcaaa atctctcaac gaaagccgtc ctgaaaatga
     5821 aaaagtttgg gttatcggtg ttgaccgtga ccaagaagca gaaggtaaat acacttctaa
     5881 agatggcaaa gaatcaaact ttgttcttgt atctactttg aaacaagttg gtacaactgt
     5941 aaaagatatt tctaacaagg cagaaaaagg agaattccct ggcggtcaag tgatcgttta
     6001 ctcattgaag gataaagggg ttgacttggc agtaacaaac ctttcagaag aaggtaaaaa
     6061 agctgtcgaa gatgcaaaag ctaaaatcct tgatggaagc gtaaaagttc ctgaaaaata
     6121 atggatggaa gtcatttctt aggaagcggc caagggccgc ttttttaaga gttgagacaa
     6181 agtcattttg tctcagtaaa gcttgctact agacaaacta gcaagtttta ttgaaataaa
     6241 ataagactct gaaaggaaga gcacatggca cacgaaaatg tcattgagat gcgtgatatt
     6301 accaaggtgt ttggtggatt tgttgccaac gacaaaatca acatgcacct acgaaaaggt
     6361 gaaattcatg cacttttagg agaaaatggg gctggtaagt ccacgctaat gaacatgtta
     6421 gcaggccttc ttgaaccaac tagtggtgaa atcgcggtca acggtcaagt tgtcaatctc
     6481 gactccccat ctaaagcagc tagcttggga atcgggatgg ttcaccagca ctttatgttg
     6541 gttgaagcct tcacagtggc tgaaaatatc attttaggta gtgaattgac taaaaatggt
     6601 gtgctagata tcgctggagc tagcaaagaa atcaaggctc tttctgaacg ttatggctta
     6661 gctgttgacc cttctgccaa ggtagcagat atctcagttg gagcccaaca acgtgtagaa
     6721 attttaaaaa cactttatcg gggggctgat atccttatct ttgacgaacc aacggctgtt
     6781 ttgactccat cagaaattga tgagttgatg gctattatga aaaatcttgt caaagaggga
     6841 aaatcaatta tcttgattac ccacaaattg gatgaaattc gagcagtttc tgaccgtgtt
     6901 acagttatcc gtcgtgggaa atcaattgaa accgttgaaa ttgcaggggc taccaatgct
     6961 gatttggcgg aaatgatggt aggacgttct gtttccttta aaacagagaa gcaagcctct
     7021 aaaccaaaag aagtggtttt gtctatcaaa gatttggtgg tcaatgaaaa ccgtggtgtt
     7081 ccagctgtta aaaatctgtc cttggatgtt cgtgctggag agattgttgg tattgcgggg
     7141 attgatggaa atggtcagtc tgaactgatt caagccatta caggtcttcg taaggttgaa
     7201 tctggtagca ttgagctaaa aggagattca attgtaggct tgcacccacg tcagattaca
     7261 gaactaagtg ttgggcacgt tccagaagac cgtcaccgtg atggcttgat tttggaaatg
     7321 atgatatctg aaaatattgc ccttcaaacc tactataaag aaccacatag taaaaatgga
     7381 attttgaact attcaaatat tacttcttat gctaaaaagc tgatggaaga gtttgatgtt
     7441 cgcgctgcca gtgaattagt tcctgcagct gcactctcag gaggaaatca acaaaaagca
     7501 attattgctc gtgaaattga tcgagatcct gatctcctta tcgttagtca gccaactcgt
     7561 gggttggatg tcggtgccat tgagtatatc cacaaacgct tgattgaaga gcgtgataat
     7621 ggcaaggctg tccttgttgt cagctttgaa ttggatgaga ttttaaacgt ctcagaccgt
     7681 attgccgtta tccacgatgg taagattcaa ggtattgtat caccagaaac aaccaataaa
     7741 caagaacttg gtgtcttgat ggctggtgga aacttgggaa aggagaagag tgatgtctaa
     7801 aaaattacaa caaatttcgg ttcccttgat ttctgtattc ctaggaattt tactcggagc
     7861 cattgtcatg tggatcttcg gttatgatgc tatttggggc tacgaagaat tgttctatac
     7921 agcctttggc agtctgcgtg ggattggaga aatcttccgt gctatgggtc ctctggtctt
     7981 gattggtctt ggttttgccg ttgccagtcg agctggtttc tttaacgtcg gacttcctgg
     8041 tcaggctttg gcaggttgga ttctcagtgg ttggtttgcc ctgtcgcatc cagatatgcc
     8101 ccgtcccttg atgattctag caaccatcgt gattgccttg attgctggtg ggattgtcgg
     8161 agcgattcca ggtattctta gggcctatct agggacgtca gaggttattg taaccatcat
     8221 gatgaactac attgtcttgt atgtagggaa tgcctttatc catgctttcc ctaaagactt
     8281 catgcaaagt acagattcga ccattcgtgt tggggctaat gcaacctatc agacaccttg
     8341 gttgactgag ttgactggta actcacggat gaatattggt attttctttg ccatcattgc
     8401 cgttgcagtt atttggttca tgctcaagaa aacaactctt ggttttgaaa tccgtgcagt
     8461 tggtcttaat ccacatgctt cagaatatgc tggtatttct gccaagcgga ctattatcct
     8521 atctatgatt atttcaggtg ccttggcagg tcttggtgga gctgttgaag gtttgggaac
     8581 cttccagaac gtctatgttc aaggttcgtc attagctatc ggatttaacg gaatggcggt
     8641 tagtttgctt gcggccaact caccaattgg tatactcttt gcagccttcc tatttggcgt
     8701 tctccaagtt ggggctcctg gtatgaatgc ggcgcaggta ccatctgagc ttgtcagcat
     8761 tgtaacagcg tctattatct tctttgtcag tgttcattac cttatcgaac gctttgtcaa
     8821 accgaaaaaa caagttaaag gaggtaagta aagatgtcta ttataacctt gctccccctc
     8881 ttggtgtctt ctatgctgat ttactcagca cctctcatct ttacaagtat cggtggtgtt
     8941 ttctctgaac gtggtggtgt ggtaaacgtt ggccttgaag gaattatggt tatgggtgcc
     9001 ttttctggag ttgtctttaa ccttgaattt gcagaacaat ttggagcagc aactccatgg
     9061 ctatccttgc ttgtagcagg attggttggt agtgttttct ctatcatcca cgcagcagcg
     9121 acggttcatt tccgtgcaga ccatgttgtc agcggtacgg tattgaactt gatggcgcct
     9181 gccttggctg ttttcttagt taaagttctt tataacaaag gacaaaccga caacctaagt
     9241 caaacttttg gacgctttga tttcccagtc ttggcaaata tcccagtgat tggtgatatc
     9301 ttcttcaagt caactagtct acttggttat ctggcgattg ccttctcatt ccttgcttgg
     9361 tttattctct ttaagactca atttggtctt cgtctccgct ctgtcggtga acatcctcaa
     9421 gcagcggata ccttgggaat caacgtctac aagatgagat atttaggggt tattatttca
     9481 ggttttctag gtggaattgg cggagcgatt tatgcgcaat caatctcagt taacttctca
     9541 gtgacaacta ttgttggacc tggatttatc gcccttgctg cgatgatctt tgggaaatgg
     9601 aatccaatcg gtgctatgct ttctagtctc ttctttggac tttcacaaag tttggctgtt
     9661 atcggttctc aattgccgtt cctacaagga gtgccagcgg tttatcttca aattgcacct
     9721 tatgttttga caattcttgt cttagcagcc ttctttggaa aagcagtcgc accaaaagca
     9781 gatggtatca actacatcaa atcaaaataa gcatacaaaa aaacgtcagt ccaatgactg
     9841 aactacaccc caaaagttag acagaaaaaa tctaactttt ggggtgtttt tattatgaaa
     9901 ttaacttatg atgataaagt tcagatctat gaacttagaa agcaaggata tagcttagag
     9961 aagctttcaa ataaatttgg gataaataat tctaatctta ggtacatgat taaattgatt
    10021 gatcgttacg gaatagagtt cgtcaaaaaa gggaaaaatc gttactattc tcctgattta
    10081 aaacaagaaa tgattaataa agtctgacat gaaggctgga ctaaagatag agtttctctt
    10141 gaatacggcc tcccaagtcg tacgatactt cttaactggc tagcacaata caggaaaaac
    10201 gggtatacta ttgttgagaa aacaagaggg agagtaccta aaatgggacg taagccaaaa
    10261 acgagacctg aagagaggac agaattagaa tatcttcaag cagaaaatga gtacctgaga
    10321 gcggagaatg ccatcctaaa aaagttaaga gaactccgat tgaaggagga aaaagagaaa
    10381 gaagaaggac agaaattgtt caagaattaa tgactgagtt ttcgttagtt cttcttctaa
    10441 aatccattaa actagctcgt tggacctact actatcactt gaaacagcta gacaaaacag
    10501 ataaggacca agagcttaaa gctgaaattc aatccatctt tatcgaacac aaaggaaatt
    10561 atgcttatcg ccgggttcat ttagaactaa gaaatcgtgc ttatctggta aatcataaaa
    10621 gagttcaagg cttgataaaa gtactcaatt tacaagctaa aatgcgacag aaacgaaaat
    10681 attcttctca taaaggagac gttggtaaga aagcagagaa tctcattcaa ggccaatttg
    10741 aaggctctaa aacaatggaa aagtgctaca cagatgtgac agaatttgcc attccagcaa
    10801 gtactcaaaa gctttactta tcaccagttt tagatggctt taatagcgaa attatcgcct
    10861 ataatctttc aacttcaccc aacttagaac aagtacaaac aatgttggaa caggtattca
    10921 cagagaagca ctatgagaat acgattctcc atagtgacca aggctggcaa taccgacacg
    10981 attcttatca tcggttccta gagagtaagg gaattcaagc atctatgtca cgtaagggta
    11041 acagcccaga caatggtatg atggagtcct tctttgggat tctgaaatcg gaaatgtttt
    11101 acggttatga gaagtcgttt cagtcgctta agcaattgga acaagctatt gtagactatg
    11161 ttgattacta caacaataaa cgaattaagg taaaactaaa aggacttagt cctgtgcagt
    11221 acagaactaa atcctttgga taaattattt gtctaacttt tggggggcag ttcacagaac
    11281 tggcatttta ttttttagga tcttgatggg ttaggttcaa tccccaaggg accaaatttt
    11341 cagttttatt tttgatacga gctatattgt ccttatgacg aatgataatc aaactagcaa
    11401 gtgctaagat aatagcgatg aagagagagt catagttact caggataaaa ccaaaaagtg
    11461 gaaagagcag aaccccgata acagccgcga tcgatgctgt gacactagac agtgaaatca
    11521 tactgccaag atagagagct ccaaagaaga taatcgcaag gtagagacag aagataggcg
    11581 caaatccgaa aatcactcca gcactggttg cgacagcctt accaccttta aatcctgcaa
    11641 agatagggaa ggtatggccg ataacagcca aaagtccaaa gatgagagga gaaacgcctt
    11701 gtagatgaaa aataatcgga agcagcgttg ctagggttcc tttgaaaaag tcaatcacaa
    11761 aggttgccat accagctttc ttacctaaaa tgcggaaggt attggtcgtt ccagtgttac
    11821 cagaaccatg ctcgcgtaga ttgatttgaa agaatacttg tccaatccag agaccagatg
    11881 gaatcgaacc cagcagatag gctaggatta ataaaattat tgtaatcata ctcctattat
    11941 atcatgaatt gggaaagaaa agcagagaat ctctgctgaa attgtcacat cggagaaaga
    12001 aaaattttgc aaaatccttg gaaaacctgt agaatagtaa agatgaacga ataggaggtt
    12061 ccttgtgtca aaaaaggaaa tcaatattaa caattataat gatgatgcta ttcaggtgct
    12121 agaagggttg gatgcggtcc gaaaacgtcc agggatgtat attggatcga ccgatggcgc
    12181 tggtcttcat cacctagttt gggaaatcgt tgataatgca gtcgatgaag ccttgtctgg
    12241 gtttggtgat cgtattgatg taactatcaa taaagacggt agtctaacgg ttcaagacca
    12301 tggacgtggg atgccgacag gtatgcacgc tatgggaatt ccaactgttg aggttatctt
    12361 taccattctt catgccggag ggaaattcgg tcaaggtggc tataagacat caggtggact
    12421 tcacggagtg ggttcttccg ttgttaacgc cctttctagc tggttagaag ttgaaattac
    12481 ccgtgatggc gcagtttaca agcaacgttt tgaaaatggt ggaaaacctg tcacgacttt
    12541 gaagaaagtc ggtacagcac ccaagtctaa aacaggcacc aaagttactt ttatgcctga
    12601 cgcgactatc ttttctacga cagatttcaa gtacaatacc atttcagagc gccttaatga
    12661 atcagccttt ctcttgaaaa atgtgacctt gtctttaacg gacaagcgat cagatgaagc
    12721 gattgagttc cactatgaga atggagtaca agattttgtt tcttatctca acgaagataa
    12781 ggaaatcttg acgccagttc tttactttga aggggaagac aatggttttc aagtggaagt
    12841 agccctccag tacaatgacg gattctcaga taacattcta tcctttgtca ataacgttcg
    12901 caccaaggac ggtggaacgc acgagacagg actcaagtct gccattacca aggtcatgaa
    12961 tgactatgca cgtaaaacag gtcttctcaa ggaaaaagat aaaaaccttg aaggttcaga
    13021 ctatcgtgag ggactagcgg ccgttctttc tatcttagtt cctgaagaac acttgcagtt
    13081 tgaaggacag accaaggata aactaggaag ccccttagct cgcccagttg tggatggaat
    13141 agtggctgat aagttgacct ttttccttat ggaaaatggg gaattagctt ctaacctcat
    13201 ccgcaaggct atcaaggccc gtgatgctcg tgaagcagca cgtaaggcgc gtgatgagag
    13261 ccgaaatggg aagaaaaaca agaaagataa gggcttgttg tctgggaaat tgaccccagc
    13321 ccaatctaag aatcctgcta agaatgaact ctatctagtt gagggggact ctgccggtgg
    13381 ttctgccaaa caaggtcgtg accgcaagtt ccaggctatt ctacctcttc gtggtaaggt
    13441 tatcaataca gccaaggcca agatggcgga tatcctcaaa aatgaagaga tcaataccat
    13501 gatttatacc attggtgcgg gtgttggagc agacttctct attgaagatg ccaactatga
    13561 taagatcatt atcatgaccg atgcggatac cgacggtgcc catatccaga ccttgctctt
    13621 gacatttttc taccgttaca tgcgtccgct agtcgaggca ggtcatgtct atattgccct
    13681 cccacctctt tacaagatgt ccaaaggtaa aggcaagaaa gaagaagtgg cctacgcttg
    13741 gacggacgga gaactagaag aactacgtaa acagttcggt aaaggcgcta ccctccaacg
    13801 atacaaagga cttggtgaga tgaatgcgga ccagctctgg gaaacaacca tgaacccaga
    13861 aacacgtacc ctcatccgtg tcacaattga agatttagcg cgcgccgaac gtcgcgtcaa
    13921 tgttctcatg ggagataagg tagaaccacg ccgtaaatgg attgaagata atgtcaagtt
    13981 tacgctagaa gaagcgacag tgttttaatg aaagaaaata atatgttagt aaactggaaa
    14041 ttagagtcgg atgtgaatga ctatgtgaaa aagcagtttg aaaatcttgg tttgaaaaaa
    14101 ttgcagaatt attaatgaag aatcttctat gagtgcttat ctcaaagagg cgtttaaggg
    14161 agcggctaag acacaaacta agactaattt tggaaaacca gattttcata ttgaaaaata
    14221 caaacaggat agtttggtta cttatcgtaa ctgaacacgg gacgaattcc cgtaaaatat
    14281 cttttactgc ataaaaacct actctacatt ctttgaaagg agttgaacac gccctagata
    14341 ttgtgtgaaa aagataaatt ctcttgtgag tttgcttact tcaagaattt tctattttca
    14401 cttggtattt tatgggcttt gtatcttatg tctaacattc aaaacatgtc cctggaggac
    14461 atcatgggag agcgctttgg tcgctactcc aagtacatta ttcaagaccg ggctttgcca
    14521 gatattcgtg atgggttgaa gccggttcag cgccgtattc tttattctat gaataaggat
    14581 agcaatactt ttgacaagag ctaccgtaag tcggccaagt cagtcgggaa catcatgggg
    14641 aatttccacc cacacgggga ttcttctatc tatgatgcca tggttcgtat gtcacagaac
    14701 tggaaaaatc gtgagattct agttgaaatg cacggtaata acggttctat ggacggagat
    14761 cctcctgcgg ctatgcgtta tactgaggca cgtttgtctg aaattgcagg ctaccttctt
    14821 caggatatcg agaaaaagac agttcctttt gcatggaact ttgacgatac ggagaaagaa
    14881 ccaacggtct tgccagcagc ctttccaaac ctcttggtca atggttcgac tgggatttcg
    14941 gctggttatg ccacagacat tcctccccat aatttagctg aggtcataga tgctgcagtt
    15001 tacatgattg accacccaac tgcaaagatt gataaactca tggaattctt gcctggacca
    15061 gacttcccta caggggctat tattcagggt cgtgatgaaa tcaagaaagc ttatgagact
    15121 gggaaagggc gcgtggttgt tcgttccaag actgaaattg aaaagctaaa aggtggtaag
    15181 gaacaaatcg ttattactga gattccttat gaaatcaata aggccaatct agtcaagaaa
    15241 atcgatgatg ttcgtgttaa taacaaggta gctgggattg ctgaggttcg tgatgagtct
    15301 gaccgtgatg gtcttcgtat cgctatcgaa cttaagaaag acgctaatac tgagcttgtt
    15361 ctcaactact tatttaagta caccgaccta caaatcaact acaactttaa tatggtggcg
    15421 attgacaatt tcacacctcg tcaggttggg attgttccaa tcctgtctag ctacatcgct
    15481 caccgtcgag aagtgatttt ggcgcgttca cgctttgaca aagaaaaggc tgagaaacgt
    15541 ctccatatcg tcgaaggttt gattcgtgtg atttcgattt tggatgaagt cattgctctt
    15601 atccgtgctt ctgagaataa ggcggacgcc aaggaaaacc tcaaagttag ctatgatttt
    15661 acggaagaac aggctgaggc tatcgtaact ttgcaactgt accgtttgac caataccgat
    15721 gtggttgtct tgcaggaaga agaagcagag cttcgtgaga agattgctat gctggcggct
    15781 attattggtg atgaaaggac tatgtacaat ctcatgaaga aagaacttcg tgaggtcaag
    15841 aagaaatttg caactcctcg tttgagttct ttagaagaca ctgcgaaagc aattgagatt
    15901 gatacagcta gtcttatcgc tgaggaagat acctacgtca gcgtgaccaa ggcaggttac
    15961 atcaagcgta ccagtccacg ttcctttgcg gcttccacct tggaagaaat tggcaagcgt
    16021 gatgatgacc gtttgatttt tgttcaatct gccaagacaa cccagcacct cttgatgttc
    16081 acaagtcttg gaaatgtcat ctacagacca atccatgagt tggcagatat tcgttggaag
    16141 gacatcggag agcatctgag ccaaaccatc acaaactttg aaacgaatga agaaatcctt
    16201 tatgtggaag tactggatca gtttgacgat gcgacaacct actttgcagc gactcgcctt
    16261 ggtcaaatca aacgggtaga gcgaaaagaa ttcactccat ggcggaccta tagatctaag
    16321 tctgtcaagt atgctaagct caaagacgat acagatcaga ttgtagcagt ggctccgatt
    16381 aaactagatg atgttgtctt ggttagtcaa aatggttatg ccctgcgttt caatatcgaa
    16441 gaggttccgg ttgtcggtgc taaggcagca ggtgtcaagg ctatgaattt gaaagaagat
    16501 gatgtcctcc aatctggctt tatctgtaat acttcgtcct tctacctctt gacccagcgt
    16561 ggaagcttga aacgtgtttc cattgaggaa attctagcaa ccagccgtgc caaacgagga
    16621 ttacaagtct tgcgtgagtt gaaaaacaaa ccgcatcgtg tcttcttggc aggagcagtt
    16681 gcagagcaag gatttgttgg cgatttcttc agtacggaag tggatgtgaa cgaccaaact
    16741 ctgcttgtcc aatccaataa aggaacaatc tatgaaagcc gattgcaaga cttgaacttg
    16801 tcagaacgca ctagcaatgg aagcttcatt tctgacacga tttcagatga agaagttttt
    16861 gacgcttatc ttcaggaagt agttactgaa gataaataag tgaaatgaag aatcagttct
    16921 aagatggttt ttattggagg aattttctga aaattacaaa atatacttgc tattttagaa
    16981 aaatagtgta gaatataaga aataggtttt tagaataagg agtggaatat gacagtaacg
    17041 attgattggg aaaacctcgg tttttcctat atgaaattac cttatcgcta tcttgctcat
    17101 ttcaaaaatg gacaatggga tcaaggagag cttacagagg atgcaacttt gcatatttca
    17161 gagtcttctc caagtcttca ctatggacaa caagcatttg aaggtttgaa agcttatcgt
    17221 actaaggatg gcagtgttca actgttccgt cctgatgaaa atgctaaacg cctgcaacgt
    17281 acatgtgacc gtctcttgat gccacaagtt ccgacagaca tgtttgtaga agcttgtaaa
    17341 gcagttgtcc gtgcgaatga agaatacgta ccaccatacg gaataggtgg aaccttatat
    17401 cttcgccctc ttttgattgg tgtcggagat attatcgggg taaaaccggc agaagagtac
    17461 attttcacca tctttgctat gccagttgga aattacttta aaggtggttt ggtcccaacc
    17521 aacttcttga ttcaggatga gtacgaccgt gcagcaccaa atggtacagg tgcggctaag
    17581 gttggtggaa actatgctgc aagtctctta ccaggaaaaa tggccaagtc acgccatttc
    17641 tcagatgtta tctatctgga cccatcaact catacaaaga ttgaagaagt cggatcagct
    17701 aatttctttg gaattacagc tgataatgaa tttgtaacac cattgagtcc atctatcttg
    17761 ccatctatta ccaagtattc cttgctttat ttggcagaac accgcttggg attaactcct
    17821 attgagggtg atgttccaat tgataatctt gaccgttttg tagaggcagg tgcctgtggt
    17881 acagcagcgg ttatttctcc aattggaggt attcaacatg gtgatgattt ccatgtattc
    17941 tatagtgaaa cagaagtagg ttctgtgacg cgtaaattat ataatgaatt gacgggtatt
    18001 cagtttggcg atattgaagc gccagaaggt tggattgtaa aagtagatta aaataaaccg
    18061 aaggagattt tttatgaaat agaaaaagtg gctcttaaca gcaggagtgg tcctgagcac
    18121 gtcagctatt ttagtggctt gtggaaaaac tgataaagaa gccgatgcac cgacaacatt
    18181 ttcttatgtc tatgcagtag atccagcatc attgggctac agtatagcga ctcgaacatc
    18241 gacgacagac gttattggaa atgttattga tggtttgatg gaaaatgata aatacggcaa
    18301 tgttgctcct tctcaaaaag actatgattt gaatagtaca ggatgggctc caagctatca
    18361 agatccagcg tcttacttga atattatgga tccaaaatct ggttttgcca tgaaacacct
    18421 tggtattacg aaaggaaaag ataaggatgt tgtagctaaa cctggtttgg ataaatataa
    18481 gaaattgtta gaagatgctg tttctgagac cactgaccta gagaagagat atgaaaaata
    18541 tgccaaagct caagcttggt cgacagatag ttcattattg atgccaacag cttcatctgg
    18601 tggttctcca gttgtaagta acgtagtacc attctcaaaa ccatactcac aagttggtat
    18661 taagggggat ccatatatct ttaaaggaat gaaattgcaa aaagatattg ttacaacaaa
    18721 agaatataac gaggttttta aaaaatggca aataccaaaa agaactagaa aaatacatta
    18781 aataaggaat ggtattgatc ttgataaaat ttttaaaata ctgtcatttt gaatataaag
    18841 gagtttgata tggagtggat tagattaata ggaatagcaa tcattgttgt gggttttatt
    18901 ttaaaatttg atacaattgc aacagtagtc ttagctggtt tggttacagc tttagtttca
    18961 ggtgtttctc tcgttgaatt tttggagatt ttgggaaaag aatttagcaa tcagcgagtg
    19021 ctcacgattt ttatggttac cttgcctctt gtggggctgt cagaaacctt tggactcaag
    19081 caacgatcaa tcgatttgat tcgaaagatt aaaggtctga cagttggaaa cttctataca
    19141 gtttatttct ttattcgaga gttagctggt ttcttttcaa ttcgtctagg aggacaccct
    19201 cagtttgtca gacctttggt tcaacctatg ggagaagcag ctgcagagtc tcaattaggt
    19261 agaaagttaa cagaggttga agatgagaca ataaaagcgc gtgcggctgc gaatgaaaat
    19321 tttggaaatt tctttgctca aaatacgttt gtaggtgctg ggggagtcct cttgataggg
    19381 ggaacattag atcagttagg ctatgaaagc aattatgcag ggattgcttc tacatctatt
    19441 attgttgctg ttataacact tattgtagtg gggatttaca attatttatt tgataaaaaa
    19501 ttgatatcaa aaaagactag gggaggagaa caaaaatgac agagttggca aagcaactat
    19561 tagagttgac ctatattgtg attggttgtc aatttctcca tacagcctat tgtagttata
    19621 aagataaaac aaacccagtt cgacttggga catctgcatt ttggactcta ttgtctatta
    19681 cgtttatagg tggttcctat atgccaaata tgagtattgg tattattgta atcctattat
    19741 cgctgttaac attgtttaag caagtccgta tcggaacctt gccatcctta gatgaaatga
    19801 aagccaatat tgaatctaac aggttgaaaa ataaaatttt tattccagtt atgctgatgg
    19861 caatacttgc gttggtctta gcgcaaatga ttccagaatt tagcaagatt tcgattagcc
    19921 ttgccgcctt gtttgctaca atttctgttc ttgtgattac caatagtcac cctaagagtc
    19981 tgttatcaga aaataatcga atgactcagc aagtttcaac aagtggtatt gttcctcaat
    20041 tattaggggc tttgggggct atttttactg tagcaggtgt tggtgatgtt atctctcatc
    20101 tgattagcgg tattgttcct tcagatagtc gctttatagg agttttggcc tatgttcttg
    20161 gaatggttct attcacaatg attatgggaa atgcttttgc agcattcacc gttattacag
    20221 caggtgttgg agttcccttt gtatttgctc tgggagctaa tccaattgtg gctggtgctc
    20281 ttgccatgac agcaggttat tgtgggacct tattgacccc aatggctgct aattttaacg
    20341 ctctaccagc agcattgatg gatatgaaag atcagaatgg cgttataaag gctcaagcag
    20401 gtgttgctct agtaatgatt gttattcaca tattcttaat gtactttctc gcattttagt
    20461 aaaggaaaat aaaatgaaaa tattggttac aggttttaat ccttttggag gtgaaaagat
    20521 taatccagct ttggaggctg taaaattatt accatctgag attaatgggg ctgaagttcg
    20581 ctgggtagaa attccaacgg ttttttataa gtcgtcagaa gttttagagg cagaaatatt
    20641 acgatatcaa ccagatgctg tactttgtat tggacaagca ggcggcagga ccggcttaac
    20701 acctgaacga gtggctatta atcaagatga tgctcgcata cctgataacg aaggcaatca
    20761 accaattgat acaccgattc gtattgatgg agcatcggcc tattttagta gtttacctat
    20821 caaagcgatg gtacaagcta tcaaaaaaca gggacttccg gcagttgtat ccaatagtgc
    20881 aggaaccttt gtttgcaatc atttgatgta ccaagctctt tatttagtgg ataaaaaatt
    20941 ccctaatatg agagcaggtt tcatgcatat tccatatatg atggaacaag tagtaaataa
    21001 gccgaatact gcaggaatga gtctatgtga tattgtaaga ggcatagagg tagctattga
    21061 agctattgta gactacaaag ataaggattt gcagttagta ggcggtgaga ctcactgata
    21121 acctaaaaag gatagtcaat tatgcttgtt tactaactat taactatgct aaatcaattg
    21181 aggttgttta cataaaactc tatatcagag aagcctgata tagagttttt tcttgctagt
    21241 tttagaattt tcttgtaaaa tagaaaaagt gaagagaggt atgaaatgag caagaaagat
    21301 aaaaaaatcg aaattcaagt agcggatgcc aaagttaatg ttggtaaaga cagttttgaa
    21361 ggttatacat tgactatcgg taaaaaagtt atcggagaaa ttgccgaatt agacggacaa
    21421 tttgccatta taaagaatgg gaatgtcgat agtttttata aaaaattgga aaaagctgtg
    21481 gaaattttga ttgaaaatta taatttagca aaataagtct tgtttttttg aaattttcat
    21541 gatataatag tccatgttga ttgtaggaga gatagcgaag aggctaaacg cggcggactg
    21601 taaatccgct ccttcgggtt cgggggttcg aatccctctc tctccatttc attaatgggg
    21661 tatagccaag cggtaaggca agggactttg actccctcat gcgttggttc gaatccagct
    21721 accccagttc ttaggtaata atcaagataa aaagcaaaat atcttagggt attttatttt
    21781 tataattgaa agacgtgaat gatatgaaca tgtccttgcg ggtgcttagg aaaaaaatta
    21841 taagtatgtc aagtttaaga aaaacttgat tgttggagga ttttttagat gaatgaattt
    21901 gaagatttgc taaatagcgt tagtcaagtt gagactggtg atgttgttag tgctgaagta
    21961 ttgacagttg atgcgactca agctaacgtt gcaatctctg gaactggtgt tgaaggtgtc
    22021 ttgactcttc gcgaattgac aaacgatcgt gatgcagata tcaatgactt tgttaaagta
    22081 ggagaagtat tggatgttct tgtacttcgt caagtagttg gtaaagatac tgatacagtt
    22141 acataccttg tatctaaaaa acgccttgaa gctcgcaaag catgggacaa acttgttggt
    22201 cgcgaagaag aagttgttac tgttaaagga acgcgtgccg ttaaaggtgg actttcagta
    22261 gaatttgaag gtgttcgtgg atttatccca gcttcaatgt tggatactcg tttcgtacgt
    22321 aatgctgagc gttttgtagg tcaagaattt gatactaaaa tcaaagaagt taacgctaaa
    22381 gaaaaccgct tcatcctttc acgtcgtgaa gttgttgaag cagctactgc agcagctcgc
    22441 gctgaagtat tcggtaaatt ggctgttggt gatgttgtaa ctggtaaagt tgctcgtatc
    22501 acaagcttcg gcgctttcgt cgaccttggt ggtgttgacg gattggttca cttgactgaa
    22561 ttgtcacatg aacgtaacgt atcaccaaaa tcagttgtaa ctgttggtga agaaattgaa
    22621 gtgaaaatcc ttgatcttaa cgaagaagaa ggacgtgtat cactttcact taaagcaaca
    22681 gtaccaggac catgggatgg cgttgagcaa aaattggcta aaggtgatgt agtagaagga
    22741 acagttaaac gtttgactga cttcggtgca tttgttgaag tattgccagg tatcgatgga
    22801 cttgttcacg tatcacaaat ttcacacaaa cggattgaaa atccaaaaga agctcttaaa
    22861 gttggtcaag aagttcaagt taaagttctt gaagttaacg cagatgcaga acgcgtgtca
    22921 ctttctatta aagctcttga agaacgtcca gcccaagaag aaggacaaaa agaagaaaaa
    22981 cgtgctgctc gtccacgtcg tccaagacgt caagaaaagc gtgatttcga acttccagaa
    23041 acacaaacag gattttcaat ggctgatttg tttggtgaca tcgaacttta atcaaattga
    23101 aaattcacaa aatcctttgt ttactaaaca agggattttt ctggctcttt gtcaactgta
    23161 gtgggttgaa gaaaagctaa gctcgagaaa ggggctcttt gtcaactgta gtgggttgaa
    23221 gt
//
LOCUS       DAVHLA010000033        22525 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVHLA010000033 DAVHLA010000000
VERSION     DAVHLA010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22525)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22525)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22525
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.033"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(<1..558)
                     /gene="ribE"
                     /locus_tag="VVO77_001498"
     CDS             complement(<1..558)
                     /gene="ribE"
                     /locus_tag="VVO77_001498"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEU5693489.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILG"
     gene            complement(543..1643)
                     /gene="ribD"
                     /locus_tag="VVO77_001499"
     CDS             complement(543..1643)
                     /gene="ribD"
                     /locus_tag="VVO77_001499"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEU5693490.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRKSPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHYVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(1777..1891)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            2048..2641
                     /gene="ruvA"
                     /locus_tag="VVO77_001500"
     CDS             2048..2641
                     /gene="ruvA"
                     /locus_tag="VVO77_001500"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEU5693491.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            2651..3214
                     /locus_tag="VVO77_001501"
     CDS             2651..3214
                     /locus_tag="VVO77_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEU5693492.1"
                     /translation="MTKRCSWVKMTNPLYITYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            3211..3888
                     /locus_tag="VVO77_001502"
     CDS             3211..3888
                     /locus_tag="VVO77_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU5693493.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSAIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLSGLLSIILV
                     GLVFALIHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(4025..5055)
                     /locus_tag="VVO77_001503"
                     /pseudo
     CDS             complement(4025..5055)
                     /locus_tag="VVO77_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
     gene            complement(5310..5993)
                     /locus_tag="VVO77_001504"
     CDS             complement(5310..5993)
                     /locus_tag="VVO77_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEU5693494.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(6005..6949)
                     /locus_tag="VVO77_001505"
     CDS             complement(6005..6949)
                     /locus_tag="VVO77_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEU5693495.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            7081..9912
                     /gene="uvrA"
                     /locus_tag="VVO77_001506"
     CDS             7081..9912
                     /gene="uvrA"
                     /locus_tag="VVO77_001506"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEU5693496.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILASVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLREGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            9905..10966
                     /locus_tag="VVO77_001507"
     CDS             9905..10966
                     /locus_tag="VVO77_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEU5693497.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLDLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASSLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            11098..11496
                     /gene="spx"
                     /locus_tag="VVO77_001508"
     CDS             11098..11496
                     /gene="spx"
                     /locus_tag="VVO77_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEU5693498.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            11562..12131
                     /locus_tag="VVO77_001509"
     CDS             11562..12131
                     /locus_tag="VVO77_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEU5693499.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGTATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            12218..12484
                     /locus_tag="VVO77_001510"
     CDS             12218..12484
                     /locus_tag="VVO77_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEU5693500.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            12488..12907
                     /gene="ruvX"
                     /locus_tag="VVO77_001511"
     CDS             12488..12907
                     /gene="ruvX"
                     /locus_tag="VVO77_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEU5693501.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            12923..13228
                     /locus_tag="VVO77_001512"
     CDS             12923..13228
                     /locus_tag="VVO77_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEU5693502.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            13487..14737
                     /locus_tag="VVO77_001513"
     CDS             13487..14737
                     /locus_tag="VVO77_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEU5693503.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLTDQVKE
                     MEKTLLQTPAQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKDGKKAVIAKLPPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLNIGLEGVYQQENAALALQTFLLFMREGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            14734..15276
                     /locus_tag="VVO77_001514"
     CDS             14734..15276
                     /locus_tag="VVO77_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEU5693504.1"
                     /translation="MTPLFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDIDG
                     TYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKIYTVNG
                     NQIVVDDMDRDPSDQIVLTK"
     gene            15422..16954
                     /gene="cls"
                     /locus_tag="VVO77_001515"
     CDS             15422..16954
                     /gene="cls"
                     /locus_tag="VVO77_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEU5693505.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIMEIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            17032..17175
                     /locus_tag="VVO77_001516"
     CDS             17032..17175
                     /locus_tag="VVO77_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693506.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            17212..18750
                     /locus_tag="VVO77_001517"
     CDS             17212..18750
                     /locus_tag="VVO77_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEU5693507.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     YFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFVHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILY
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            18870..21077
                     /gene="nrdD"
                     /locus_tag="VVO77_001518"
     CDS             18870..21077
                     /gene="nrdD"
                     /locus_tag="VVO77_001518"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEU5693508.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTD"
     gene            21089..21229
                     /locus_tag="VVO77_001519"
     CDS             21089..21229
                     /locus_tag="VVO77_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693509.1"
                     /translation="MGKYQLDDKGCAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            21273..21779
                     /locus_tag="VVO77_001520"
     CDS             21273..21779
                     /locus_tag="VVO77_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU5693510.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKFQSPHDGGFWDTENFVYEDWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            21772..22362
                     /gene="nrdG"
                     /locus_tag="VVO77_001521"
     CDS             21772..22362
                     /gene="nrdG"
                     /locus_tag="VVO77_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEU5693511.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLEFLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            22370..>22525
                     /locus_tag="VVO77_001522"
     CDS             22370..>22525
                     /locus_tag="VVO77_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleoside-triphosphate reductase"
                     /protein_id="HEU5693512.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNPNY"
BASE COUNT         6695 a         4275 c         5016 g         6539 t
ORIGIN      
        1 acctaagata tcattttcaa gatttactgt actcccgact tgtttactct taagaatggt
       61 ttgttccaag gtatgaggga taacagatac tgaaaagttt actttggaga ctttagcgac
      121 agtcagacta atgccgtcaa ttgtaataga tcctttttca actattaaat ctaaaatttc
      181 tttttgtgtg ttgatttgat accatacagc attatcatct ttttttattg acgagatttt
      241 tcctgtacca tcaatgtgtc ctgtaacgac gtgaccccca agtcgaccgt tgacagataa
      301 ggctctttct agattcacct cacttccatg ttttaataga gtaagagctg ttcgactcca
      361 tgtttcattc attacatcaa ctgtaaagga ttgatgattg aaatgagtaa ctgtaagaca
      421 gataccattt actgctatac tatcgcctaa atggatatcc gttaatattt ttgaggcttt
      481 aattgatagt ttacaattac gagagtcttt ctgtattctt tcaacttttc cgatttcttc
      541 aattattcct gtgaacatgg ataaatcact tcactttcta tgagatagtc atttcctatt
      601 tgagaaaaag cataaggttt caatctaata gcgtcatttg gcaaagaaat gccttcacct
      661 ccgacaggaa acttggcact gcctccaaaa atttttggtg caatatatat tttcagctca
      721 tcaacaattt gttgttccaa agcactccaa ttcattagac tgcccccttc tagaactagg
      781 ctatcaatct gcatgtttcc tagatgttgc attaaactcg ataagtctat atgattgcct
      841 tttttcttta tggaaagtat ttcacagcca tgattttgat atagcttcat tttatttttg
      901 tcttcagagg aagtggcaat gtaagtttta atatcatttg ctgtttttac gattttagag
      961 gtaagaggag ttcgtaaatg tgtatcgcat atgatacgga taggattttt cccttcctcc
     1021 aatctacatg tcagcaaagg atcgtcttga ataacagtat tgactcccac cataattgca
     1081 ctaacatagt gtcgtaactg atgcacatgc tttcttgctt cttcttcagt aatccatttg
     1141 gattgatttg ttttagtggc tatttttcca tccattgaca ttgcatattt cataaaaaca
     1201 tagggtacat gctgggtaat atactttcta aaacttttta ttaagttaag acactcattt
     1261 tctaaaattc caacagtaac ttgaagatta ttttcctcaa gtatctttac tccttttcca
     1321 gatacaatag gattacagtc taggcttcca atgactactc ttgtaatacc actatcgatt
     1381 atagcatcta tacagggagg tgttttcccg aagtgacaac agggttcaag tgttacataa
     1441 agcgtcgctc cgacagggga ttttctacag tttttaagag catttctctc agcatgtggg
     1501 ccaccaaaaa actcatgata accttgtccg ataatgtgat tatcttttac aataactgcg
     1561 ccgaccatag gattgggatt gacgtaacca gccccttttt gtgccagttt tattgctaat
     1621 ttcatatatt ttgaatcgct catctcacta cctccaaaaa aatatacctt gaatagggga
     1681 ctactcaagg catacaaaag aaaacttatg cgattaacaa aaatgctctg aaatgacaag
     1741 taatcatttc agagcacgca aaaagcacaa atatactttt atcttctttc atccagacta
     1801 tactgtcggc tttggaattt caccaaatca tgcctttcgg ctcgtgggct ataccaccgg
     1861 tagggaattg caccctgccc tgaagatagt tattcaatta cagatgatta tagtacttaa
     1921 ttttgaatat gtcaacagat aaataccgat tgtttttgat atactgtatt tgtgataatc
     1981 gattctcgct cctcggataa agaaaatatg atatactaga taaacgaaat aagagagaag
     2041 gaacactatg tacgcatatt taaaaggaat cattaccaaa attactgcca aatacattgt
     2101 tcttgaaacc aatggtattg gttatatcct gcatgtggcc aatccttatg cctattcagg
     2161 tcaggttaat caggaggctc agatttatgt gcatcaggtt gtgcgtgagg acgcccattt
     2221 gctttatgga tttcgctcag aggatgagaa aaagctcttt cttagtctga tttcggtctc
     2281 tgggattggt cctgtatcag ctcttgctat tatcgctgct gatgacaatg ctggcttggt
     2341 tcaagccatt gaaaccaaga acatcaccta cttgaccaag ttccctaaaa ttggcaagaa
     2401 aacagcccag cagatggtgc tggacttgga aggcaaggta gtagttgcag gagatgacct
     2461 tcctgccaag gtcgcagtgc aagcaagtgc tgaaaaccaa gaattggaag aagctatgga
     2521 agccatgttg gctctgggct acaaggcaac agagctcaag aaaatcaaga aattctttga
     2581 aggaacgaca gatacagctg agaactatat caagtcggcc cttaaaatgt tggtcaaata
     2641 ggagcagaga atgacaaaac gttgttcgtg ggtcaagatg accaacccgc tctacatcac
     2701 ctatcatgat gaggagtggg gccagcccct ccatgatgac caagcattgt ttgagttgtt
     2761 gtgtatggaa acctatcagg caggcctgtc ttgggaaacg gtactcaaca aacgccaagc
     2821 tttccgagaa gcctttcata gctatcaaat tcactcagtc gcagagatga ctgacactga
     2881 attggaagcc atgctggaga atccagctat cattcgaaat agagccaaga tttttgctac
     2941 acgcgctaac gcccaagcct ttctacagtt acaggcagag tacggctctt ttgatgccta
     3001 tctttggtct tttgttgagg ggaaaactgt cgttaacgat gttcctgatt atcgccaagc
     3061 cccagctaaa acacccttat ctgagaaatt agccaaagat ctcaaaaaac gaggcttcaa
     3121 gttcacaggc ccagtcgccg tattgtcttt tctacaggct gcagggctag ttgatgacca
     3181 cgagaatgat tgtgagtgga aaggtcttaa atgatgtcta acaaaaataa gggaattctg
     3241 atttttgcga ttctctatac agtcctcttt gtgtttgatg gcgttaaatt gctggcttct
     3301 ttaatgccat ctgccattgc aaattatctt gtttatgtag ttttagcttt atatggctcc
     3361 ttcttgttca aggatagatt gatccaacaa tggaaggaga ttagaaagac taaaagaaaa
     3421 ttcttctttg gagtcttaac aggatggctc tttctcattc tgatgactgt tgtctttgaa
     3481 tttgtatcag agatgttgaa gcagtttgtg ggactagatg gacaaggtct aaatcagtct
     3541 aatattcaaa gtacctttca agaacaacca ctactgatag ctgtttttgc ttgtgtcatt
     3601 ggacctctgg tagaagaatt atttttccgt caggtcttat tgcattactt gcaggaacgg
     3661 ttgtcaggtt tactaagcat tattctggta ggacttgttt ttgctctgat tcatatgcac
     3721 agtttggctc tatcagagtg gattggtgca gttggttact taggtggagg ccttgccttt
     3781 tctattattt atgtgaaaga aaaagagaat atctactatc ccctacttgt tcacatgtta
     3841 agcaacagcc tctccttaat cattttagct atcagtatag taaaatgaaa tgagaacagg
     3901 acaaatcgat ttctaacaat gttttagaag tagaggtgta ctattctagt ttcaatatac
     3961 tgtaatatgt gatgaaaatg ccagtaatga taccgagaaa aaagctgaga aacttttccc
     4021 agctttattt gttatagtca aagagaatga cttgttcctg tgcatctaca tgagcatgga
     4081 ccccaaaggg tacaattgct cttggagttg cgtggccgac attcagatta tagacaatcg
     4141 ggatattgct gtcaatgata tccaatagtg cctctttata gtcgtcatgg aaagtttcat
     4201 ccataggttt tccgaccaag agtccattga tgaccgcgaa tatgccagtg tcctttaaag
     4261 ttagcaacat ctttttgaag tcttctggct taggcttttc ttcgcttgtt tcgagcaaga
     4321 ggattttccc ttcccagtct gacaagtcag ggaaaagttt gtatttttgg cagagttccg
     4381 tgctatctgc gtatcgagag ttgtcaaaga tatcgtagag ggattcgagg caaccaccga
     4441 ggattttccc ctcgaactgg gcacttcctt gcaacaagtc aaaacctgta tttgtatgac
     4501 tgacacgagg tgttcccagg gccgtgggac taaaatcagt tcgttcctca taccaaacgt
     4561 cactagggcg gatttctgaa attcttcccg tctcaatcaa ttctttaaag tagtgaaggc
     4621 tataggctag catttctttg tctaattcac aaatgtctgc taaaaaggat tgaccataaa
     4681 aagtcttgat tcctaattta tgcaacatga ggtggttcat ggttgtatcc gagaagccaa
     4741 gaaaaatttt ttgtttgata cccttttgga gttggtcatt ttcaaaaaga taaggtagca
     4801 agcgataggc atcgtctcca ccgatggcac ataggatcat gtcgatctat catcagaaaa
     4861 ggcatgaatc aaatcctctg cacgagcttc aggatggtcc ttgataaagt ctaatccttt
     4921 taacgaatgg ggcaaaaaga tgggattgag tcccagatcc ttgagacgtt ggatacccaa
     4981 gtccacttcg tgtttgacaa aatcctctcc gataatgcca ctagataaac taacaatacc
     5041 aatagtagaa accatatctc atcctcctag aaatagattg agcctatttt atcacaaaat
     5101 ataagagaaa gctatgtggg atttcagaag aatactttta atactcttcg aaaatctctt
     5161 caaaccacgt cagttttatt tgcaacctca aagctgtgct ttgagcaacc tgcagctagc
     5221 ttcctagttt gctctttgat tttcattgag tataactcaa aaaagtaagt gaaaaagcaa
     5281 ccgcacctgc agttgctttt atcgttttct tattcttgat agcgtgttgg tcctgcactt
     5341 gcactacgga tattcaagcg tttcttgaga tagaagcgaa gggctaggag ggctgctcca
     5401 ataatagcta gtggcaatgg atccagtact gggttaaggc tagctggtag gaagcttgtt
     5461 gcaaagaaga caagcaacca aaggaacata gaagctagga taactagtac agatttccag
     5521 aaaggtggac gttgactgcg atccatatct ggtccatagt attggtaaac aaagtagtac
     5581 atcaagtaga aggcaaatcc accaaccagt ccaactaata gaagagtaat caatccatag
     5641 ccgaaagctt gatctgccgc aaagaaggtt gtgagggcgc tgacaagggc aaagaggcta
     5701 gtgatgaaaa gagctgagtc cataatcatc agttttggat catcattttc ttttggatgc
     5761 tctttttcgt actgctcttt gacagtgaag ctatgagccc aatgagttgg tgcgccgtat
     5821 agggaacggg cagttgtacc tttagattgc tcctcaagga tttggggaat gacttcctca
     5881 aaaatagtct ggatttcagc gtctgttttc ccatctttga tgaattgttg ggtagcaatg
     5941 tggacaaact cttggttttt cttagttaat ttttgtagat caatttgaga cataggaact
     6001 cctcttagaa ccatttttta tggatgagat agagagtgag cgagacactc atagcaaagg
     6061 cgataaagac gattaaccag aaggcatttg gctctccgtt tagggggatt tcattatcct
     6121 taaagttcat cccgtaggca gaaaagacca tggttgggat ggacatgacg atggtcacaa
     6181 gggccaaggt tttcatgatg ttgttctggt tgttagaaat gatagaggca aaggtctctg
     6241 tcatagaatg caagacgttt ccataaatat ctgccatctc gatggcctgt tgggtttcaa
     6301 tcagggtgtc ttcaagcagg tcttcgtctt caaggtattt cttgatattg ctggttgaac
     6361 tggtcaattt cttaatcacg cgctcatttg ttttgaggga ggccttgaaa tagacgatag
     6421 ttttttccaa ttccatgagc tcaatcaatt cttcattacg agttgattga tgcagttgac
     6481 tttcgatttg ttcactcttg cggtcgattg aacgaagggc tgttaggtaa agctctgcat
     6541 tgcgataaag aatttgaaag ataaaacgtg aacgcatgaa ggtatagaaa ttacgcaatc
     6601 gacggttgat aaagacatca aggacaggta gtggttccaa acacgtagtg ataatggttt
     6661 cctcagtgat gataatacca agcgggatgg ttacgtagta ggtgcggtta tttctttcct
     6721 ccgtgaccgg cacgtctacg ataatcaggg tatactcgtc ttcaatggta atacgagaca
     6781 tttcttccgc atcgagcggt gctcgaaggt cggcaatatc aatatcgaag gtgttggcga
     6841 tttcgagtga ttcattttga gtcggattga cgagattgat ccaagtaccc ggttcaagcg
     6901 tatcgatctc tttaaattca gttgttgtag agagaaaaac ttgtttcata tcccttatcc
     6961 tttctcattt ttcagatttt ttcacactgt actattatac tacaaaatcg gccttttggg
     7021 taatagaatc tcactttttt tggtataatg gtaagcaata atggactaga aagaacaaag
     7081 atgcaagata aaattgtcat tcatggggcg cgtgcccata atttaaaaaa tattgatgtg
     7141 gagattccgc gagacaagtt ggttgtcgtg actggcttgt caggttcagg gaagtccagt
     7201 ctggcttttg ataccctcta tgcggaggga caacgtcgct atgtagagag tttgtccgcc
     7261 tacgctcgtc agttcttggg aaatatggaa aaaccagatg tagatgccat tgatggtctc
     7321 agtccagcta tttctatcga ccagaaaacg actagcaaaa accctcgctc gacggtggga
     7381 acaacgactg aaatcaatga ctatctgcgt ctcctctacg cacgtgtggg gacgccttac
     7441 tgtatcaacg gacatggagc tatcaatgct tcttctgtgg agcaaatcgt tgataaggtt
     7501 ttggagttac ctgaacgcca gcgcttgcag atcttggcct ctgtcatccg caagaaaaaa
     7561 ggccaacata agagtgttat cgagaaggtt cagaaagacg ggtatgttcg tgtccgtgtg
     7621 gatggggaag tctatgatgt gaccgaagtg ccagagttgt ctaagagcaa gcaacacaat
     7681 atcgatgtcg tggttgaccg tattgttatc aaggagggca ttcgtagtcg tctctttgat
     7741 tccattgagg ctgcccttcg tattgcagaa ggttatgtca ttatcgacac catggacgac
     7801 tctgagttgt tgttctctga gcattatgcc tgtccagttt gtggttttac tgtcccagag
     7861 ttagagcctc gtctcttctc tttcaatgct ccttttggct cttgtagtga gtgtgacggc
     7921 ttgggcatca agctggaggt ggatactgat ttggtagtgc cagatgccag caaaacctta
     7981 cgtgagggag cgttagcacc ttggaatcct atctcatcca actactatcc aaacatgtta
     8041 gagcaggcca tgaaagtatt tggagtggct atggataagc cttttgagga cctgtcagaa
     8101 gaagataaga acttgattct ctatgggtca gatggtaagg aattccattt ccactatgag
     8161 aatgaatttg gtggcgtgcg cgatatcgac attccgtttg agggagttat caataatatc
     8221 aaacgtcgtt accatgaaac caatagcgat tacactcgca ctcagatgcg tctctacatg
     8281 aatgagctga cctgcggaac ctgtcaaggc tatcgtctca atgaccaggc cttgtctgtc
     8341 cgtgtgggcg gccagcaagg gccacatatt ggagaaatct cagacctgtc tatcgctgac
     8401 cacttggact tggtgagcca gttaactttg tctgaaaatg aagccatcat tgctcgtccc
     8461 attctcaagg aaatcaagga tcgtttgacc ttccttaata atgtgggtct taactatcta
     8521 accctgtcac gttcagcagg aaccctttca ggtggggaaa gtcagcgcat tcgtttggca
     8581 acccagattg gttccaacct atcaggcgtc ctctatatcc tagacgagcc gtcaatcggt
     8641 cttcaccaga gagacaatga ccgcctgatt gccagtctga aaaagatgcg tgacttgggc
     8701 aatactctta tcgtggtgga acacgacgaa gataccatgc gtgaagctga ttatctgatt
     8761 gacgttggtc ctggtgccgg tgtttttggt ggtgagattg ttgcagcagg tacacctaag
     8821 caagtggctc gcaacagcaa gtctatcaca ggtcagtact tgtcaggcaa acgtgtcatc
     8881 ccagtaccag aagagcgccg tgtcggaaat ggtcgtttta ttgaagtgat aggagcgcgt
     8941 gagaacaact tgcaaaatgt cacggctcgc tttccactag gaaaatttat cgcagtgaca
     9001 ggtgtgtcgg gttcagggaa atcgactcta atcaacagca ttctcaaaaa agccattgcc
     9061 cagaagctca accgtaattc agacaaacct ggtaagttta agactattac agggattgag
     9121 catgtcgacc gtttgattga tattgaccag agccctatcg gacggacgcc gaggtctaac
     9181 ccagctacct atacaggagt ttttgacgat atacgtgacc tttttgctca gacaaatgaa
     9241 gccaagattc gaggctacaa gaaggggcgc ttcagtttca acgtcaaggg aggtcgctgt
     9301 gaagcttgct caggtgacgg gattatcaag attgagatgc acttcttgcc agatgtttat
     9361 gtggcttgtg aagtttgcca cggaacccgc tataacagtg aaaccctaga agttcactac
     9421 aaggaaaaga atatttcgca ggtcttggat atgacggtca acgatgcggt agaatttttc
     9481 caacacattc cgaaaattca acgcaaactc cagaccatca aggatgtagg gctaggctat
     9541 gtgaccttgg gacagccagc taccaccctt tctgggggag aagcccaacg tatgaagtta
     9601 gctagcgaac tccacaaacg ctcgacagga aaatctttct acattctgga tgagccgacg
     9661 acagggcttc atacagagga cattgctcgc ctgctcaagg ttttagctcg ctttgtagac
     9721 gatggcaata cagtcctcgt catcgagcac aatctggatg ttatcaagac ggcagaccat
     9781 atcattgact tgggacctga gggcggtgtc ggtggtggaa ccatcatcgt aacaggaact
     9841 ccagaagaag tagctgccaa tgaagccagc tatacaggac actatttgaa aggaaagtta
     9901 catcatgaat aaacgcgtac aagcatttct agctaaaatg caagaaaaag aactagatgg
     9961 tatcatcatc aacaatctta aaaacgtcta ttatttgact ggtttttggg gctcaaacgg
    10021 aacagtcttt atcagccgtg accgtcaggt cttagtgaca gactctcgct atatcatcgc
    10081 agctaagcaa gaaaccagtg gttttgagat tgtggctgat cgtgatgaat tggctgtcat
    10141 tgcaggaatt gttaaggaca tgggcttgac tcgtatcggt tttgaagatg agatttcagt
    10201 atcttattac caccgtatgc aggcagcttt tgcaggtttg gacttgcttc cacaaactca
    10261 atttgtggaa ggtcttcgta tgattaagga tgaggcagag attgcagcga ttcgcaaggc
    10321 ttgttctatc tcagaccaag ctttccgcga tgcgcttgac tttatcaaac caggaaaaac
    10381 tgaaattgaa attgccaact tccttgattt ccgcatgcgt gagttgggag catctagctt
    10441 atcttttgat acgatcctag ctagcggtat caattcttct aaaccccatg cccatccaat
    10501 gcacaaacca gtggagttgg gagaagccat taccatggac ttcggctgtc tctatgacca
    10561 ctatgtcagt gatatgaccc ggactatcta tctagggcat gttagcgatg agcaggcaga
    10621 gatttacaat acggttctaa aagctaacca agccttgatt gaccaagcta aggcaggctt
    10681 aggtttccgt gactttgaca aaatccctcg tgatattatc attgaggcag gttatggcga
    10741 ctactttact cacggcattg gccacggtat tggtctggat atccatgagg aaccctactt
    10801 tagccagact tctacagaaa ctattaagac aggtatggcc ttgaccgatg aaccaggtat
    10861 ctatatcgaa ggcaaatatg gcgttcgtat cgaggatgat atcctgatta cagagacagg
    10921 ttgtgaatta ttgaccctag ctccaaaaga gttgatagtc atttagttgt ttgtcaagaa
    10981 aaaagtacga aaatgacgaa aaaagtcaaa aaaaattaaa aataggtcgc aagtcggatg
    11041 ttttttatgg tataatagac taaactgata gtaacatgta gcgaaagggg taggtacatg
    11101 attaaaattt atacagtctc aagttgtact agctgtaaaa aagcaaaaac ctggctcaat
    11161 gcccaccagt taagttataa agaacaaaac cttggtaaag aaggaattac gagagaagaa
    11221 ttactggata ttctaaccaa aacagataac ggaatagcca gcatcgtttc gtctaaaaat
    11281 cgctatgcca aagcccttgg agtggatatt gaagatttga gtgtcaatga agttctcaat
    11341 ctgattatgg aaacaccgag aattttaaag agcccaatcc ttgtagatga aaaacgcctg
    11401 caagttggct acaaggaaga cgatattcgt gccttcctac cacgctctgt ccgtaatgta
    11461 gaaaatgcag aagcacgttt acgtgcagct ctataaacat caaggctggg agcacttccc
    11521 agtcttattc tattttaatt tcaaaaagaa agaagagaga aatgaaaaaa atagttcttg
    11581 ttagtctagc tttccttttt gtcctggttg gttgcggaca gaaaaaagaa actggaacag
    11641 ctacaaaaac agaaaaggat acgcttcagt cggcattgcc agttattgaa aatgccgaga
    11701 agaatacagt tgtaaccaag actttggtct tgcccaagtc agatgatggt agccagcaaa
    11761 ctcaaaccat tacatacaag gacaagactt ttttgagctt aacgattcaa caaaaacgtc
    11821 cagtttctga tgagttgaag acttatatcg accaacatgg agtggaagaa actcaaaaag
    11881 ctcttcttga agcggaggag aaggataagt ctatcattga agctcgtaaa ttggcaggtt
    11941 tcaaacttga aacaaaacta ttgagcgcaa cggaacttca aacaacgact agttttgatt
    12001 ttcaagttct ggatgtcaag aaggcttccc agttggaaca tctgaagaat attggtttgg
    12061 aaaatctttt gaaaaatgaa ccaagcaaat atatttcaga tagattggca aatggcgcga
    12121 cagaacaata gaaaatccaa ataaatagac tgcctgaatt gtagaaggta aggaattatg
    12181 ctataatggt actattctaa ggaaagaggg tgttagaatg ggatttactg aagaaacagt
    12241 acgttttaaa ttggacgatt ccaataaaaa agaaattagc gaaactttga cagatgttta
    12301 tgcttcgttg aacgataagg gttacaaccc aattaaccaa atcgtaggtt acgtattgag
    12361 tggagaccct gcctacgttc ctcgttataa taatgcacga aatcaaatcc gtaagtatga
    12421 gcgtgatgaa atcgttgagg aattggttcg ttactacctc aaaggacaag gagtcgatct
    12481 ataacctatg agaattatgg gattggacgt cggttcaaaa acggtagggg tggcgattag
    12541 cgatccgctt ggttttacag ctcaagggct tgaaatcatc cagataaatg aagaacaagg
    12601 ccaatttggt tttgaccgcg ttaaggaatt ggttgatact tacaaggtag aacgatttgt
    12661 agtgggcttg cctaaaaaca tgaacaatac aagtggaccg cgcgtagaag ctagtcaagc
    12721 ctacggagca aagctagaag agttttttgg tttaccagta gactatcagg atgaacgctt
    12781 gacaacagtg gctgctgagc gcatgttgat tgaacaagca gatatcagtc gcaataagcg
    12841 caagaaagtc attgataagt tagcagctca gctgatttta caaaattatt tagatagaaa
    12901 attttaatat aaaggagagg ctatgtcaca cgatcataac cacgaccacg aagaacgtga
    12961 actaatcaca ctagtagatg agcaaggaaa tgaaaccttg tttgaaatcc ttttgacaat
    13021 tgatggaaaa gaagaatttg gtaaaaacta tgttcttcta gtaccagtta acgcagaaga
    13081 agacgaagac ggacaagttg aaatccaagc ttactcattc attgaaaatg aagatggaac
    13141 agaaggcgaa ttgcaaccaa tcccagaaga ctcagaagac gaatggaaca tgattgaaga
    13201 agtcttcaac agctttatgg aggagtgata cagtctggga gactgtatca gcccaactcc
    13261 cagaaatggg gaagagttgg aacgtccagt gaacattttt accccaactc ttagaacttg
    13321 agaagagttg gaacatctag tggatgtttt tagcccatat tcacattcat agtagctagt
    13381 tattagctaa ccaggtaaga ggtcgggacg aaaatcctgg ccttgttttt attagtaacc
    13441 atactttaat gcgataattg attggacttt tgtcaaggag atgtgtatgt ttgaagtaga
    13501 agaatggctc catagtcgga ttggtttgaa ttttcgatca ggtttgggcc gaatgcagca
    13561 agcggtggat ttgttaggaa atcctgagca gtcttaccct attatccacg taacagggac
    13621 taatgggaaa ggatctacca ttgcttttat gagggaatta tttatggggc atggcaaaaa
    13681 agttgcgacc tttacctccc ctcatatcgt ctctatcaat gaccgaatct gcattaatgg
    13741 gcaacctata gcagacgcag actttatccg tttgactgat caggtcaaag agatggagaa
    13801 aacgcttctg caaactcctg cccagttgtc cttttttgaa ttgctgacct tagttgcttt
    13861 tctttatttt agggagcagg aggtggattt ggttttatta gaagtgggaa ttggtggctt
    13921 acttgacacg accaatgtgg taactggaga gcttgctgtc atcacctcca ttgggcttga
    13981 ccatcaagaa accttgggtg atagtctaga agcaattgca gagcagaaag ctggtatttt
    14041 caaggatggt aagaaggcag tgattgcgaa attgcctcca gaagctaggc ttgtctgtca
    14101 gaaaaaagcc gaatctttag ctgttaacct ttatcaggca ggtcaagatt ttttaatgct
    14161 gaatggtgat ttttcaagct ctttactaaa tctttcacag ctgaacatag gcttagaagg
    14221 agtctatcag caggagaatg cagccttggc gttgcaaact tttcttcttt ttatgagaga
    14281 aggaaaggaa gctgttgatg aacaggctgt aagaaaggcc ttggaacaga cccattgggc
    14341 tggtcgcttg gagcgtattc gcccacagat ttacttggat ggtgctcata acctccctgc
    14401 cttgactcgc ttggttgagt ttatcaaaga aaaagagcag gaaggctatc gacctcaaat
    14461 cctctttgga tccttgaaac ggaaggatta tcaagggatg ttgggttatc tgactgaaaa
    14521 tttacctcaa gtggaactca aaatgaccgg ctttgactat caagggtctt tggacgagac
    14581 agatgtcaca ggttaccatg taattccctc ttaccgagaa tttatcagca gtttcgaaga
    14641 aagggcagac gctcaagact tgctgttcgt tacagggtct ctctatttta tctcagaagt
    14701 acggggctac ctgctggacc gtgagcagat aaattgaccc ccttgtttga acttgttata
    14761 ctaggggaat tgctggttag agaaaatttc tctaaattgg tagcagaaag gaaattcatc
    14821 atgaaattaa aaagattcac actttctctt gcttctctag caagttttag tctcttagta
    14881 gcttgttcac aaagagctca acaggttcaa cagcctgttg ctcagcaggt ccaacagcct
    14941 gctcaacaga ataccaatac tgcaaatgca ggaggtaacc aaaatcaagc ggctccagta
    15001 caaaaccaac ctgttgctca accgaccgat attgatggga cttatactgg tcaggatgac
    15061 ggagaccgta tcactttagt ggtaactgga acgactggta catggactga gctcgaatct
    15121 gacggggatc agaaagtcaa acaggttaca tttgattcag caaatcaacg catgattatt
    15181 ggcgatgatg tcaaaattta cactgtaaac ggtaatcaaa tcgtcgtaga tgatatggat
    15241 agagacccat cggaccaaat cgttttaact aaataagact atgcaagtag aaagggctgg
    15301 atttttcagc ctttttactt ttacctagaa aataatcata aatacttgcc ttctaccgaa
    15361 tacctgcgtt atactagtat caattacttg tttttagcat tcaaactatc aaggagggga
    15421 tatgaaatat aggaaatttc aattattgat gtccaagtat ggctttagtc tttcgattat
    15481 gctacttgaa ctttgtcttg tttttggtct ctttctttat ttaggacgca tggctcccat
    15541 tttatggatt actgtcctca ttctactgag tatcatcaca atcatttcga tagtcaaccg
    15601 taatacgact cctgagaata aggtaacctg gttgttagta gcctttgtgc cagtatttgg
    15661 tcccttgctc tatctgatgt ttggtgaaag gcgattgtcc aaaaaagaaa tcaaacaact
    15721 gaagaagcta ggctctatgc atttccaaga agcaaatagc cagctactaa aagagaaatt
    15781 aaaagaaagt gacaaggcag cttatggagt catcaagtcc ttattgagta tggataccaa
    15841 tgctgacatc tatgatcaaa ctgcctctac attttttcct aacggagaag ctatgtggaa
    15901 aaagatggta gaagatctta aaaaggctga gaaatttatt ttcttggaat attacattat
    15961 agaagaaggt ttgatgtgga atcgcatact agatatacta gagcaaaagg tagctcaggg
    16021 tgtagaggtt aagatgctct atgatgatat cggctgtatg gctactttaa caggagatta
    16081 tgcacatcga cttcgtcagc tgggcatcga ggcccataaa ttcaataaag ttattcctcg
    16141 tttgacagtg gcttataata acagagatca tagaaaaata ttgattgttg atggtcagat
    16201 agcctatact ggtggggtca atctggcaga tgagtacatt aaccacgtcg agagatttgg
    16261 ttattggaag gatagtggaa ttcgcttaga cggactagca gtaaaagccc tgacacgctt
    16321 atttttgacc acttggtaca ttaatcgagg agaaattagt gattttgatc aatatcattt
    16381 agaaaatcat tctatcccga gtgacggttt aaccattcca tacggaagtg gacccaagcc
    16441 aatttttcga gcgcaggtag ggaaaaaagt ttatcagagt ttaatcaatc aagcaacgga
    16501 atcggtctat attacgacac cttatttgat tatagattat gatttaacag agacaatcaa
    16561 aaatgcagct atgagagggg tcgatgttcg aattatcacc ccttacatac cagataagaa
    16621 gttcattcag ttagtcacga gaggggctta tcccgacctt ctttctgctg gtgttcggat
    16681 ttatgagtat agtccaggtt ttattcatag taagcagatg ttggtagacg aagattttgc
    16741 ggtggtgggg acaatcaatc tcgactaccg gagcttggta caccattatg aaaatgcagt
    16801 cttactctat aaaactcctt ctataatgga aatcgcccga gattttcgaa atatatttgc
    16861 agattctcag gaagtctatc ctcattctat caaaacgagc tggtatcaaa agcttgtaaa
    16921 agaaatcgcc cagctattcg cccctatctt ataagaaatc tagaacttag gatacaaacc
    16981 agacctattt ttcttgtctt ttacgaatag aaagaaagag gaggggaatt catgctaact
    17041 aaggaagaag tgaatgatat gattgagttc aaacagacac atttacaccg ctttcgggaa
    17101 attgaaacct ttgtgaaact atgcaaaaaa tcactcaaac agccatcgca agctgacaat
    17161 cctaggactt tttgatatac taagacagat aaattgaaca ggagaaacga tatgagtgtg
    17221 tatggtagag tagaagaagt tcataaggag aatcgtgaac ctctagaata ccaaatcgaa
    17281 caagaatcgc atcatcgtga atcaagtcgt cttcctttgg tgaaaatttt actatggagt
    17341 acgcttgtaa cggggataac tctaggagta ccgctattac tcgacttaat gagtgcacaa
    17401 gaagtgcagg atttttatgc aggttgggcg cttcatcaga cagggaagat ttacagcgac
    17461 tattatggaa gtcaaggttt gctttattat ttgctgactt acgtgagtca gggcggatat
    17521 ttctttgcca tctttgagtg gttagccttg gtagcaggag gatttttcct ttttagatca
    17581 gcggacacct tgacagagca aggagaccaa gctggacatc tggtgactat tttttacatg
    17641 ctagttacag gtcttgcttt tggtggaggc tatgcgactc ttttagcgct tcctttctta
    17701 ttcgcagcct ttagtttagt tgcggcttac ctaagcaatc caagccatga taagggattt
    17761 gtacggattg ggctagcttt ggcaggcgga tttttctttg ctcccttatc atcgctcctg
    17821 tttattgctg tagtgagttt aggcttgttg gtctttaacc ttgggcatag acgttttgtg
    17881 catgggtttt atcagtttct tgcagtggct ttaggttttt cacttgtctt ttatccaact
    17941 gcctactata gtgctgcaac aggaagtttt ggggatgcga ttagtggtat tcgttatcct
    18001 attgacagta ttcgctttga ttttacttct aaaattttag agaatatgtt tttttatggc
    18061 ttgttgtccc ttggtttggg atttgtggtt tgtatctttt taggtctctt tcaatccaaa
    18121 ccctttaaac tatacgtcat ttcggttcct gcaagtcttg tggtaatttt aggtttgatt
    18181 ttacttttct tttcacaaga gcctctgcac gcttcttatt tgatggtcgt cttccctgtt
    18241 ttcctacttt tattggtaac caatattaag agtcaacaga gggggcgtag tgctagaaga
    18301 agccgaagag aaacgccagt tagcctatgg agtcgtttct tcaaaggaaa tctatatctg
    18361 ctagtttttg ggtttgtcta tcttttgtct gttccttttt tgatgaagtt tgtcctttat
    18421 ccagtacctt atcaagaacg taatcgtctt gctgatttgg taaaagagga gacaaatacg
    18481 gaagatgcta tctatgcatg ggatgatact gcgactcttt atcgtaagag tgagcgcttg
    18541 tcgccatcgg cgattttgta cccgttgcac tatacagcaa ctgaagaaaa tcgtaataag
    18601 ttacttaatg acttgaaaga aaaacaacct aaggtgattg tggtaaatga caaggtggta
    18661 gtctggtctg aagtggaaac actcttaaaa gaaaattacc aacaagtaaa gactgattac
    18721 tcagagttta aagtctataa aattaaataa ccaaatcaat atcttgtgta tttttaaaaa
    18781 ttttaggatt tttaacacaa gatattgatt tttcttttta gagtggtata atacttttta
    18841 gaaagaacat tttagaaaag agcatgcata tgattgcact agaagaaaaa attacaattt
    18901 tgccaactct cttcgtcgag aaacgagatg ggagacgtgt tgtatttgat gtggacaaga
    18961 ttgacaaggc tctccacaag gcggctgaca aggttatgga tgtgacaccc ctggttgaaa
    19021 aacgcctcaa tgatctgact gagcgaatta ttacagaaat tcatagtcgc tttccacagg
    19081 gaattaagat ttacgaaatt caaaatatcg tagaacatga actccttgaa gccaaagaat
    19141 atgcactggc tgaggagtat attacttatc ggacacagag ggattttgag cgctcaaaag
    19201 cgacggatat caactttagt attcataaac ttctcaacaa agaccagaca gttgtcaatg
    19261 aaaatgctaa taaagacagt gatgtcttta acactcagcg tgatttgaca gcagggattg
    19321 ttgggaaatc aatcggactg caaatgcttc ctaagcacgt agccaatgcc caccaaaagg
    19381 gggatatcca ctatcacgat ttggactaca gtccctatac ccctatgacc aactgctgtt
    19441 tgattgattt taagggtatg ttggaaaatg gttttaagat tggaaatgca gaggtagaga
    19501 gtcccaagtc tatccagact gcgacagcac agatttctca aatcattgcc aacgttgctt
    19561 ctagccagta cggtggctgt tcagctgacc gtatcgatga aattttggcg ccttatgcag
    19621 agaagaacta tcaaaaacat ctcaaagatg cagaagagtg ggtattgcct gaaaaacggg
    19681 aagattacgc ttggaagaaa acgcaaaagg acatctacga tgccatgcaa tctcttgagt
    19741 atgaaatcaa tactctcttc acttcaaatg gacaaacacc ttttacttcg ctaggttttg
    19801 gtctgggaac cagtcgtttt gaacgagaaa ttcaaaaagc tattttaaac attcgcatca
    19861 agggtcttgg ttcagaacac cgtacggcta tctttcctaa acttattttc actctgaaaa
    19921 gaggccttaa tttagaggaa ggaactccca actacgacat caagcagttg gctcttgagt
    19981 gtgcaaccaa acggatgtat ccagatgttt tatcttacga taagattgtt gacttgacag
    20041 gatccttcaa ggtgcctatg ggttgccgtt ctttcctcca aggatggaag gatgaaaatg
    20101 gtgtagaagt caattcaggt cgcatgaatc tgggtgttgt gacggttaat ctgcctcgta
    20161 ttgctcttga gtctgaaggt gatatgaata agttctggga aatcttcaac gagcgaatga
    20221 atatcgcaga agatgctctt gtttaccgtg tcgaacgcac taaagaggcg acaccagcga
    20281 atgctcctat cctttatcag tacggtgctt ttggccatcg tctaggtaaa gaagaaagtg
    20341 ttgaccagct ctttaagaat cgtcgtgcga ccgtttcgct gggctatatc ggcttgtatg
    20401 aagtagcgac agttttcttt ggtaacagct gggaaagtaa tccagatgct aaggaattca
    20461 cgctagacat cattcacgat atgaaacgcc gtgtagaaga gtggtcagac caatatggct
    20521 accatttctc tatctactca acaccatccg aaagtctgac agaccgtttc tgtcgactag
    20581 atatagacaa gtttggctct attcctgata tcacagacaa ggaatactac accaactctt
    20641 tccactacga tgttcgtaaa aatccaacac cgtttgaaaa attggacttt gagaaagtct
    20701 atccagaagc aggtgcgtca ggtggtttca tccattattg tgagtatcca gtccttcagc
    20761 aaaatccaaa ggccttggaa gctgtctggg attatgctta tgaccgtgta ggctatctag
    20821 gcaccaatac tccgattgac cgttgctaca agtgtgactt tgaaggggat tttgaaccaa
    20881 ctgagagagg gtttgcttgt ccaaactgtg gcaatagcga ccctaaaaca gtagatgtgg
    20941 tgaagcgaac ttgtggctac ctaggtaatc ctcaagcaag accgatggtc aacgggcgtc
    21001 acaaggaaat cgctgcgcgt gtcaaacata tgaatggttc aacgattaaa atagctgggc
    21061 atcaagtaac agattagaaa gaaatgaaat gggaaaatat caactagacg ataaggggtg
    21121 cgcacaagtg acccgttatc acgagaaaca ctctaaaggt ggagctggta agaaagaacg
    21181 cttgcttagc ttcagagaac aatttttaaa caagaacaag aaaaaataaa agtgagagcc
    21241 agctctcgct tttctcatag tgggaggtaa ggatggaatt acgcagacca agattagcgg
    21301 ataagaaagc tgttttagat atgatgacag agtttgaaaa atttcagtcg cctcacgacg
    21361 gcggtttctg ggatacagag aactttgtgt atgaagactg gttagaaagc aatcaggaac
    21421 aggaaatggg gattaatctg cctgaaggat gggttcctgc aattcagtta gtggcttttt
    21481 ctgagaaagg tcaagcagtt ggatttctta atctccggtt gcgcctcagt aactttctac
    21541 tagaagaagg tggccacatt ggctactcca ttcgtccatc tgaaagaggc aagggttatg
    21601 caaaagagac tctccgtcag ggcttgcaag ttgctaagga aaagaacatc aagaaagctc
    21661 tggtgacctg tagcgtgaat aatcctgcta gcagagcagt cattctagca aatggtggaa
    21721 tatttgagga tgctcgcaat ggagtcgagc gttattggat agaggtagcg aatgaataat
    21781 ccaaaaccac aagaatggaa aagcgaggaa cttagtcaag gtcgtatcat tgactacaag
    21841 gcctttaact ttgtggacgg cgaaggcgtg cgtaactctc tctatgtatc aggctgtatg
    21901 tttcactgcg agggatgtta taatgttgcg acttggtctt ttaatgctgg cattccctat
    21961 acagcagaat tagaagagca gatcatggca gatcttgctc agccctatgt tcaaggtttg
    22021 actttgttgg gaggggagcc ttttcttaat actgggattc tcttgccact tgttaagcgg
    22081 attcggaagg aattgccaga caaggacatc tggtcctgga ccggctacac ttgggaagaa
    22141 atgatgttgg aaactccaga taaactggaa ttcttgtcac tgattgacat tcttgtcgat
    22201 ggaagatatg atcgaactaa gagaaatctt atgctccagt ttcgaggttc atctaaccaa
    22261 cgaattatcg atgtgcaaaa atcgctcaaa agtgggcaag tagtgatttg ggacaagctc
    22321 aatgacggaa aagaaagcta tgaacaggtg aagagagaat gaagaaaaaa tgaagaaaaa
    22381 agacttagta gaccaactag tctcagagat cgagacgggg aaagtcagga cactgggaat
    22441 atacggtcat ggagcttcag gtaaatcaac ctttgcacag gaattgtacc aagctttaga
    22501 ttctactaca gtaaacccca attat
//
LOCUS       DAVHLA010000034        21947 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVHLA010000034 DAVHLA010000000
VERSION     DAVHLA010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21947)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21947)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21947
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.034"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            <1..696
                     /locus_tag="VVO77_001523"
     CDS             <1..696
                     /locus_tag="VVO77_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="phosphoenolpyruvate-dependent sugar
                     phosphotransferase system; functions with enzymes IIB
                     (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for
                     anaerobic utilization and uptake of L-ascorbate; sgaTBA
                     are regulated by yifQ as well as Crp and Fnr; IIB is
                     phosphorylated by IIA and then transfers the phosphoryl
                     group to the sugar; IIC forms the translocation channel;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU5693513.1"
                     /translation="LILGPDIMSNKEVITSGTLFNPAKQDFFMYIIQTAFTFSVYLFV
                     LMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAASYGFGSPNAVLSGFTFGLIGQLI
                     TIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRGGWKAAVILSFISGVLQVALGAL
                     CVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIVGYVLVCLFLLVIPQLQFAKAKD
                     KEKYYNGEVQEEA"
     gene            719..1000
                     /locus_tag="VVO77_001524"
     CDS             719..1000
                     /locus_tag="VVO77_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU5693514.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            1077..1562
                     /locus_tag="VVO77_001525"
     CDS             1077..1562
                     /locus_tag="VVO77_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU5693515.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            1579..2244
                     /locus_tag="VVO77_001526"
     CDS             1579..2244
                     /locus_tag="VVO77_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEU5693516.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDIFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            2248..3111
                     /locus_tag="VVO77_001527"
     CDS             2248..3111
                     /locus_tag="VVO77_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEU5693517.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFIEMSIDERDERL
                     ARLDWSKEERLEVVKEIYETGVRIPSICFSGHRRYPLGSKDSVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIS
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            3113..3817
                     /locus_tag="VVO77_001528"
     CDS             3113..3817
                     /locus_tag="VVO77_001528"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEU5693518.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVAWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            3996..5669
                     /locus_tag="VVO77_001529"
     CDS             3996..5669
                     /locus_tag="VVO77_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU5693519.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQMSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            5781..6872
                     /gene="ulaG"
                     /locus_tag="VVO77_001530"
     CDS             5781..6872
                     /gene="ulaG"
                     /locus_tag="VVO77_001530"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEU5693520.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            6986..8962
                     /gene="tkt"
                     /locus_tag="VVO77_001531"
     CDS             6986..8962
                     /gene="tkt"
                     /locus_tag="VVO77_001531"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU5693521.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGINTFGASAPAPKVLAEYGFTVENLVKIVRNLK"
     gene            9079..9378
                     /gene="yajC"
                     /locus_tag="VVO77_001532"
     CDS             9079..9378
                     /gene="yajC"
                     /locus_tag="VVO77_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEU5693522.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            9425..9853
                     /locus_tag="VVO77_001533"
     CDS             9425..9853
                     /locus_tag="VVO77_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEU5693523.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            9855..10265
                     /locus_tag="VVO77_001534"
     CDS             9855..10265
                     /locus_tag="VVO77_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693524.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            10565..13216
                     /gene="adhE"
                     /locus_tag="VVO77_001535"
                     /gene_synonym="adhC"
     CDS             10565..13216
                     /gene="adhE"
                     /locus_tag="VVO77_001535"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEU5693525.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSVHA
                     ARIVRDAAIAAGAPENCVQWITEPSMEATSALMNHEGIATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFRPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
     gene            complement(14202..14510)
                     /locus_tag="VVO77_001536"
     CDS             complement(14202..14510)
                     /locus_tag="VVO77_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU5693526.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(14507..14815)
                     /locus_tag="VVO77_001537"
     CDS             complement(14507..14815)
                     /locus_tag="VVO77_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU5693527.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            complement(14820..16115)
                     /locus_tag="VVO77_001538"
     CDS             complement(14820..16115)
                     /locus_tag="VVO77_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU5693528.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTKFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLALVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(16133..17542)
                     /locus_tag="VVO77_001539"
     CDS             complement(16133..17542)
                     /locus_tag="VVO77_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEU5693529.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTEDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYDNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            17700..18428
                     /locus_tag="VVO77_001540"
     CDS             17700..18428
                     /locus_tag="VVO77_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU5693530.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            18887..19081
                     /locus_tag="VVO77_001541"
     CDS             18887..19081
                     /locus_tag="VVO77_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU5693531.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSGVTLITGKNGTGKSTLL"
     gene            complement(19447..20757)
                     /locus_tag="VVO77_001542"
     CDS             complement(19447..20757)
                     /locus_tag="VVO77_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEU5693532.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNFAITNGTLDVLAQHILYRTRTYPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGKTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTSIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            20994..21866
                     /locus_tag="VVO77_001543"
     CDS             20994..21866
                     /locus_tag="VVO77_001543"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEU5693533.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFKRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALDDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
BASE COUNT         6882 a         3945 c         4464 g         6656 t
ORIGIN      
        1 ttaatcttgg gtccagacat tatgtctaat aaagaagtca tcacttcagg aactctattc
       61 aatcctgcta aacaagattt ctttatgtac attatccaaa cagcctttac cttctcagtt
      121 tacttgttcg ttttgatgca aggtgtccga atgttcgtat ctgagttgac aaacgccttc
      181 caaggtattt caaacaaatt gttgccaggt tcattcccag cggttgacgt tgcagcttct
      241 tatggatttg gttctccaaa tgctgtcttg tcaggattta cctttggttt gattggtcaa
      301 ttgattacaa ttgtcttgct catcgtcttt aaaaatccga ttcttattat tacaggattt
      361 gtaccagtgt tctttgacaa tgcagccatt gcggtctacg ctgataaacg cggcggatgg
      421 aaagcggctg ttatcctttc ctttatatca ggtgtccttc aagttgctct aggagctctt
      481 tgtgtggccc ttctcgattt ggcatcttat ggtggctacc atggaaatat cgactttgaa
      541 ttcccatggc ttggatttgg atatatcttc aaataccttg gtattgttgg ttatgtactt
      601 gtgtgtctct tcttgcttgt tattcctcaa cttcaatttg ccaaagcaaa agataaagag
      661 aaatattaca acggtgaagt tcaagaagaa gcttagtatc tagaaaagga gaaataaaat
      721 ggttaaagta ttagcagcgt gcggaaatgg aatgggttca tcaatggtta tcaagatgaa
      781 ggttgaaaat gctctccgta agcttaatca aacagatttt acagtcaatt catgcagtgt
      841 cggtgaagct aaaggtttag cagtaggata tgacatcgta atcgcttctc ttcatttgat
      901 tcaagaattg gaagggcgaa ctaatgggaa gttaattggg cttgataact tgatggatga
      961 taaagaaatc accgaaaaac tcagtcaagc actacagtaa aaggttggag ggggctggac
     1021 agaaactgag agttatcgtt tctgtccttc tccctcttta aataaaggag gcagatatga
     1081 atttaaaaca agctttaatt gacaatgact cgatccgact aggtttagag gctaacaatt
     1141 ggaaagaagc agtcaaggta gcagtagatc ccttaattga aagtggggca attttgccag
     1201 agtattacga tgctatcatt gaatcgactg aagagtatgg gccttactat atcttgatgc
     1261 caggtatggc tatgccccac gctagacctg aagctggtgt gcaaagtgat gccttttcat
     1321 tgattacctt acaaaatcct gttgtatttt cagatgggaa agaggtatct gttttgttgg
     1381 cactagcagc aacaagttca aaaattcaca caagtgtagc cattccacaa attattgccc
     1441 tgtttgaatt agaagattct attgcacgtt tacaggcttg ccagactaaa gaagatgtct
     1501 tggctatgat tgaagaatct aaggatagcc cttatctcga aggattggat ttggaaagtt
     1561 agaaagagga ataaagaaat gacaaaaaga atacctaatt tacaagttgc attagaccat
     1621 tcagacttgc aaggagcgat taaagcagct gtttctgttg gtcaggaagt agatattatc
     1681 gaagctggaa ctgtttgctt gcttcaagtt ggaagtgaac tggctgaagt cttgcgtagc
     1741 cttttcccag ataagattat tgtggcagac acaaaatgtg ctgatgctgg tggaacagtt
     1801 gctaaaaata atgcggttcg tggagcagac tggatgactt gtatctgttg tgcaaccatc
     1861 cctactatgg aagcagctct aaaggctatc aagactgaac gaggagaacg aggcgaaatc
     1921 cagatcgagc tttatggcga ttggactttt gaacaagctc agctttggct agatgcaggt
     1981 atctcacaag ctatttatca ccaatctcgt gatgctcttc ttgctggtga aacttggggt
     2041 gaaaaagacc ttaataaggt taaaaaactc attgatatgg gcttccgtgt atctgtaaca
     2101 ggtggtctag atgtagatac tctcaaactc tttgaaggtg ttgatatctt tacctttatc
     2161 gcaggtcgtg gaattacaga ggctgcggat ccagcaggag cagcgcgtgc cttcaaggat
     2221 gaaatcaaac gaatttgggg gtaaatcatg gtacgtccaa ttggaattta tgaaaaggca
     2281 accccaacac actttacttg gctagaacgt ttaaattttg ccaaggagtt aggctttgat
     2341 tttatcgaga tgtctattga cgaacgtgac gagcgtttag caagacttga ctggagtaag
     2401 gaagaacgct tggaagttgt caaagaaatc tatgaaactg gtgttcgtat tccttctatc
     2461 tgtttttcag gccatcgtcg ctacccattg ggatcaaaag attcagttct agaggaaaaa
     2521 tctctagaac tcatgaaaaa atgtatcgaa ttagctcaag acttgggagt tcgtacgatt
     2581 caattagctg gttacgatgt ttactatgag gaaaagtcac cccagacacg ccaacgtttt
     2641 atcaaaaatt tgagaaaagc ctgtgactgg gctgaagaag ctcaggtggt acttgctatt
     2701 gaaattatgg atgatccttt catcagtagc atcgaaaaat atttggctat agaaaaagag
     2761 attgactctc ccttcctctt tgtatatcca gatattggta atgtgtctgc atggcataat
     2821 gatatctata gtgagtttta tcttggtcat catgccatcg cagctctcca tctcaaggat
     2881 acttatgcag tgacagaaag ttcaaagggc cagttccgag atgtaccttt cgggcaaggt
     2941 tgtgtcaaat gggaagaagc tttcgatatt ttaaaggaaa ccaattataa tggacctttc
     3001 ctaatcgaaa tgtggtctga aaattgtgaa acagtagaag aaacacgcgc agccattcaa
     3061 gaggcgcaag cttttctcta tccactcatt aagaaagcag gtttgatgta agatgaatca
     3121 agtaatcaat gctatgcgta aacgagtctg tgatgccaat caatcattgc caaaacatgg
     3181 acttgtcaaa tttacctggg ggaatgtatc tgaagtcaat cgcgaactcg gtgtcattgt
     3241 tatcaaacca tcaggcgtgg attatgacga attgacacct gaaaacatgg tagtgactga
     3301 tctagatggt aagatcctag aaggggattt aagaccatct tccgacctcc caactcatgt
     3361 gcaattatat aaggcttggt cagaaattgg tagtgtggtt cacacccatt cgacagaagc
     3421 tgttgcttgg gctcaggcag gtcgtgatat tcctttctac ggaacaaccc atgcagatta
     3481 tttctacggt tcaattcctt gcgcccgtag tttgaccaag gacgaagtag aagtggccta
     3541 tgaaaaagat actggcctgg ttatcgtaga agagtttgaa catcgcggac ttaacccggt
     3601 tgaagtacca ggaattgttg tacgcaatca cggtccattc acctggggca aaaatccaga
     3661 gaatgctgtt tatcactctg tcgtactaga ggaagtatca aagatgaatc gctttacaga
     3721 acaaatcaat ccaagagttg gacctgctcc ccagtacata ctagaaaaac actaccaacg
     3781 taaacatgga ccaaatgctt attatggtca aaagtaagaa cgatgaagga ggagaaaaag
     3841 ataaatttag ctcctctttt tacatttgat ttttattgag agtaaagttg gagttgaagt
     3901 aattttaaaa gattttttag aaatagcgct tgatatatat atggtaaaat aaaaagaatt
     3961 gctgtgatat caatagattt gggggatttt ttaatatggt actggataag gcaagttgtg
     4021 atttgcttca atatttgatg gatcaagaaa cgtccaaaac gattatggcg atttcgaaag
     4081 atttgaaaga gtcaagaagg aaaatttatt atcacattga caaaatcaat gctgctctgg
     4141 gtgacgaggc gcttcacatc attagtattc cacgaattgg tattcactta acggaagagc
     4201 agagagatgc ttgttgtaaa ctattatcgg aagtagattc gtacgattat atcatgagtg
     4261 cgcatgaacg tatgatgata atgttactat ggataggtat ttctaaagaa cgtattacga
     4321 ttgaaaaatt gatagagtta acagaggtat ctaggaatac tgttctcaat gatttgaata
     4381 gtattcgtta tcaactaact ttggaacaat atcaggtgat cttgcaaatg agcaagtcac
     4441 agggatacca ccttcatgcc caccctctta ataaaattca gtatcttcaa tcgcttctat
     4501 atcatatttt tatggaagaa aatgccactt ttgtatctat tttagaagat aagatgaaag
     4561 agaggttaga tgatgagtgt ttgctttctg ttgaaatgaa ccaatttttt aaggaacagg
     4621 ttcctttagt tgaacaagat ttagggaaga aaataaatca tcatgaaata acttttatgt
     4681 tgcaggttct accttatttg ctgttaagct gtcataatgt tgaacagtat caagaaagac
     4741 atcaggatat agagaaagaa ttttctttga taagaaaaag aatagagtat caggtgtcta
     4801 agaaattagg agaacggttg tttcaaaagt ttgaaatttc tttgtcagga cttgaagttt
     4861 ctcttgtagc tgttctcctc ctctcctatc gtaaagattt ggatattcat gcagaaagtg
     4921 atgattttcg gcaattaaaa cttgctttag aagaatttat ctggtatttt gaatcacaaa
     4981 tccgaatgga gattgagaac aaggatgatt tgttacgaaa tttgatgatc cactgtaaag
     5041 ccttgttatt tagaaagact tacggtattt tttctaaaaa tcctctaaca aaacaaattc
     5101 gatccaagta tggagaatta tttttagtca ctagaaaatc tgcggaaatt ttagaaggag
     5161 catggtttat tcggctaaca gacgatgata ttgcctattt gacgattcat attggaggat
     5221 ttttaaagta tacaccatcg tctcaaaaaa atatgaaaaa agtttatctc gtttgtgatg
     5281 aaggtgttgc ggtttcgaga cttttgctga aacaatgcaa actttatttt ccaaatgagc
     5341 aaattgacac tgtatttaca acagaacaat ttaagagtgt ggaagatatt gcacaagttg
     5401 atgtagtgat tactactaat gatgatttgg atagcagatt tccgatttta agggttaatc
     5461 ctatccttga agcagaagat attttgaaaa tgctagacta tcttaaacac aatatatttc
     5521 gtaataagag caaaagtttc agtgaaaatc tttctagtct tatttcgtct tatattgtag
     5581 acagcaagtt ggctagtaag ttccaagaag aggttcaaac acttataaat caagaaatag
     5641 tagttcaagc ttttttggaa gatatttgaa ggacagtcca atgatgaaca caaacctgtg
     5701 tttttcttgg tcttttttag tgttttgaag ggtggtatac taatctcaaa gataacaatt
     5761 atatccaaag gaggcaacat atgccaaacg tcaaagaaat tacaagagag tcatggattt
     5821 tagccacttt cccagagtgg ggaacatggt tgaacgaaga aatcgaagaa gaagtcgtac
     5881 ctgaaggcaa ctttgccatg tggtggctag gcaactgtgg tacttggatt aagacaccag
     5941 ctggtgctaa cgttgtcatg gacctttggt caaaccgtgg aaaatcaacc aaaaaagtga
     6001 aagatatggt tcgtgggcac caaatggcaa atatggcagg tgttcgtaaa ttgcaaccaa
     6061 acttgcgtgt tcagccaatg gttatcgatc catttgctat caacgaacta gactattact
     6121 tagtttcaca cttccacagt gatcatatcg acccatacac agctgcagca attctcaaca
     6181 atcctaagtt agagcatgtt aagtttatcg gtccttacca ctgtggacga atctgggaag
     6241 gatggggggt tccaaaagaa cgtatcatcg ttgttaaacc aggtgacact atcgaattaa
     6301 aagatatgaa gattcatgca gtagaatcat ttgaccgtac ttgcttggta actctcccag
     6361 tgaacggtgc tgatgagaca ggcggtgaac ttgctggctt ggctgttaca gatgaagaaa
     6421 tggctcaaaa ggctgttaac tatatctttg aaacaccagg tggaaccatc tatcatggtg
     6481 cagattctca cttctcaaac tattttgcaa aacatggtaa agactttaaa attgatgttg
     6541 ctttgaataa ctatggtgaa aatccggtag gtatccaaga caaaatgaca tctatcgacc
     6601 ttcttcgtat ggcagaaaat ctgcgtacca aagtcattat cccagttcac tatgatatct
     6661 ggtctaactt catggcttct actaatgaga ttctagaact ttggaaaatg cgaaaagatc
     6721 gcttgcaata cgatttccat ccatttatct gggaagttgg cggtaagtac acttatcctc
     6781 aagatcaaca cttagtagaa taccatcatc cacgtggttt tgatgattgt tttgaacaag
     6841 actctaacat tcaatttaaa gctttgctat aatataaaaa tattctttgg aggttatccg
     6901 tatgttgcat gatacggata attttcatat aatagtaaaa tagaatgtgt gattcaataa
     6961 tcacctcaaa tagaaaggaa attctatgtc aaatctatct gttaatgcaa ttcgttttct
     7021 aggtattgac gccattaata aagccaactc aggtcatcca ggtgtggtta tgggagcggc
     7081 tccgatggct tacagcctct ttacaaaaca acttcatatc aatccagctc aaccaaactg
     7141 gattaaccgc gaccgcttta ttctttcagc aggtcatggt tcaatgctcc tttatgctct
     7201 tcttcacctt tctggttttg aagatgtcag catggatgag attaagagtt tccgtcaatg
     7261 gggttcaaaa acaccaggtc acccagaatt tggtcatacg gcagggattg atgctacgac
     7321 aggtcctcta gggcaaggga tttcaactgc tactggtttt gcccaagcag aacgtttctt
     7381 ggcagccaaa tataaccgtg aaggctacaa tatctttgac cactatactt acgttatctg
     7441 tggagacgga gacttgatgg aaggtgtctc aagcgaggca gcttcatacg caggtttgca
     7501 aaaacttgat aagttggttg ttctttatga ttcaaatgat atcaacttgg atggtgagac
     7561 aaaggattcc tttacagaaa gtgttcgtga ccgttacaat gcctacggtt ggcatactgc
     7621 cttggttgaa aatggaacag acttggaagc catccatgct gctatcgaaa cagcaaaagc
     7681 ttcaggcaag ccatctttga ttgaagtgaa gacggttatt ggatacggtt ctccaaacaa
     7741 acaaggaact aatgctgtac acggcgcccc tcttggagca gatgaaactg catcaactcg
     7801 tcaagccctc ggttgggact acgaaccatt tgaaattcca gaacaagtat atgctgattt
     7861 caaagaacat gttgcagacc gtggcgcatc agcttatcaa gcttggacta aattagttgc
     7921 agattataaa gaagctcatc cagaactggc tgcagaagta gaagccatca tcgacggacg
     7981 tgatccagtc gaagtgactc cagcagactt cccagcttta gaaaatggtt tttctcaagc
     8041 aactcgtaat tcaagtcaag atgccttgaa tgttgtggca gctaaattac caaccttcct
     8101 aggtggatca gctgaccttg ctcactcaaa catgacttat atcaagacgg atggacttca
     8161 agacgatacc aatcgcttga atcgtaacat tcagtttggt gttcgtgaat ttgcaatggg
     8221 aacaatcttg aacgggatgg cccttcatgg tggacttcgt gtatacggtg gaactttctt
     8281 cgtcttctct gactatgtga aggcagctgt ccgcttgtca gccttacaag gacttcctgt
     8341 gacttatgtc tttacccatg attcaatcgc agttggggaa gatggtccga ctcacgaacc
     8401 ggttgagcat ttagcaggtc ttcgtgctat gccaaatcta aatgttttcc gtccagcaga
     8461 tgcgcgtgaa acgcaagcag cttggtacct tgcagtgaca agtgagaaaa caccaactgc
     8521 ccttgtcttg acacgtcaaa acttgactgt tgaagatgga acagacttcg acaaggttgc
     8581 taaaggtgct tatgttgtat atgaaaatgc agccgacttt gataccatct tgattgcgac
     8641 aggttcagag gttaatcttg ctgtctcagc tgctaaagaa ttggctagtc aaggcgaaaa
     8701 aatccgcgta gtcagcatgc catctacaga tgtctttgat aaacaagatg cagcttacaa
     8761 ggaagagatt cttccaaatg cagtccgccg tcgtgttgca gtcgaaatgg gtgcaagtca
     8821 aaactggtac aaatatgttg gtctcgatgg tgccgttcta ggtattaata ccttcggagc
     8881 ctctgcccca gcaccaaaag tattggcaga atatggcttt actgtagaaa atcttgtaaa
     8941 aattgttcga aacttgaaat aatcctaaaa atcagggcgt aagctctggt ttttcttacc
     9001 agaaaagtaa ggtacaatct tgtaaaagta gctgaaattt gatatagtag tcctatgtaa
     9061 aagacaaagg agaaaacaat gaatccaaat attacttttt taatcatgct tgtaggtatg
     9121 atggccttga tgttctttat gcaacgttct caaaagaaac aagctcaaaa gcgtatggaa
     9181 agcttaaata aactacaaaa aggctatgaa gtgattacaa tcggtggact ttatggaaca
     9241 gtcgatgaag tagatacgga gaagggaaca atagttcttg acgtagatgg agtttacttg
     9301 acttttgaac tagctgctat caagacagta ttaccgctga aagaaacagc ttcactagaa
     9361 ggcgcaattg aaaaataaga cgggatcacg aactcccgtt tttctataaa agaaaggaaa
     9421 tgggatgaaa aaattagtct ttgtctgtct gggaaatatt tgccgtagcc ctatggccga
     9481 gtttgttatg aaatcaatga cagataacta cgaaatccaa agtcgagcaa cttcctcttg
     9541 ggaacatggc aatccgattc ataaggggac tcagggaatt tttcaagagt atgagattcc
     9601 ttatgacaag aacaagacat cgcttcagat tagtaaggaa gattttgaag cctttgatta
     9661 tattatcgga atggacgctt caaatatttc tgacttacgt cagatgtgtc cagtagactg
     9721 tcaagataag atttactcat tttcatctga aagtgttcca gacccttggt atacaggaga
     9781 ttttgaagaa acctatcgac gtgttcaaga gggctgtcaa gcttggttag aacgtttaga
     9841 aaaggagagt taaggtggaa aatcttacga atttttacga aaagtatcgt gtctatctga
     9901 ctcgtccacg attagagctt ttggcagtag ttaccattgt tttctgtgct gtactcgtct
     9961 tttttctaaa tattccagga aaaggtgtct taaaactcga taatggaacg attgtttatg
    10021 atggcagtct tgtccgtggt aaaatgaatg gtcaaggtac cattaccttc caaaatggag
    10081 accaatatac aggtggcttc aacaatggag ccttcaacgg aaaaggtacc tttcaatcta
    10141 aagaaggctg gacctacgaa ggtgattttg taaatggtca ggctgaagga aaagggaaac
    10201 taacaacaga acaagaagtc gtttatgaag gaacttttaa acaaggcgtt tttcaacaaa
    10261 aataaagcct ccttatcaaa ggaggtatta ttagaatcgc aaggtaagcg cttacctgca
    10321 aatccctttc tttccaaatc cctcttccaa ccaagtttgt gaaataaaaa atatttgaaa
    10381 taaatttcac aaacttcaaa gataaaacct gataagaaaa gaaaatgaga aaagtttcac
    10441 aagagtttaa aaattctttg tgaaatgttt atgaaactgt ttacaaagtt gaaataatgc
    10501 gttataataa acttgtgaaa aaattaacaa aggatatcgt tccttgaaag ctatggagga
    10561 aaatatggct gataaaaaaa ctgtgacacc agaggaaaag aaactcgttg ctgaaaaaca
    10621 cgtagatgag ttggttcaaa aagctctagt tgcccttgaa gaaatgcgta aattggatca
    10681 agaacaagtt gactacatcg ttgccaaagc atcagtagca gctttggatg cccacggaga
    10741 attggcttta catgcctttg aagaaacagg acgtggtgta tttgaagata aagcaactaa
    10801 gaacttgttt gcttgtgaac acgtggtaaa caacatgcgt cacactaaaa cagttggcgt
    10861 tatcgaagaa gatgatgtaa caggattgac cctgattgct gaaccagttg gtgttgtttg
    10921 tggtatcact ccaacaacaa acccaacatc aacagcgatc ttcaaatcat tgatttcatt
    10981 gaagacacgt aatccaatcg tctttgcctt ccatccatca gctcaagaat catcagttca
    11041 tgcagctcgt atcgtccgcg atgcagctat cgcagctggt gctcctgaaa actgtgtaca
    11101 gtggatcact gaaccatcta tggaagcaac tagtgccctt atgaaccacg aaggtattgc
    11161 aacaatcctt gcaacaggtg gtaatgccat ggttaaagcc gcatactcat gtggtaaacc
    11221 agctcttggg gtaggtgccg gaaacgttcc agcttatgtt gaaaaatcag caaacattcg
    11281 tcaagcagca cacgatatcg tcatgtctaa atcatttgat aacggtatgg tctgtgcatc
    11341 tgaacaagca gttatcattg ataaagaaat ttacgatgaa tttgtagcag agttcaaatc
    11401 ttaccacact tactttgtaa acaaaaaaga aaaagctctt cttgaagagt tctgcttcgg
    11461 cgtcaaagca aacagcaaaa actgtgctgg tgcaaaattg aacgctgaca tcgttggtaa
    11521 accagcaact tggattgcag aacaagcagg atttacagtt ccagaaggaa caaacattct
    11581 tgctgcagaa tgtaaagaag ttggcgaaaa tgagccattg actcgtgaaa aattgtcacc
    11641 agttattgca gttttgaaat ctgaaagccg tgaagatggt attactaagg ctcgtcaaat
    11701 ggttgaattt aacggtcttg gacactcagc agctatccac acagctgacg aagaattgac
    11761 taaagaattt ggtaaagctg ttaaagctat tcgtgttatc tgtaactcac cttctacttt
    11821 tggtggtatc ggggacgttt acaatgcctt cttgccatca ttgacacttg gatgtggttc
    11881 ttacggacgc aactcagttg gggataacgt tagtgccatt aacctcttga atatcaaaaa
    11941 agtcggaaga cggagaaata acatgcaatg gatgaaactt ccttcaaaaa catactttga
    12001 acgtgattca attcaatacc ttcaaaaatg tcgtgacgtt gaacgtgtca tgatcgttac
    12061 tgaccatgcc atggtagagc ttggtttcct tgatcgtatc atcgaacaac tggaccttcg
    12121 tcgcaataag gttgtttacc aaatctttgc ggatgtagaa ccggatccag atatcacaac
    12181 tgtaaaccgt ggtactgaga ttatgcgtgc cttcagacca gataccatca tcgcactcgg
    12241 tggtgggtct ccaatggatg ctgccaaagt aatgtggctc ttctacgagc aaccagaagt
    12301 ggacttccgt gaccttgtcc aaaaattcat ggatatccgt aaacgtgcct tcaagttccc
    12361 attgcttggt aagaagacta aattcatcgc gattccaact acatctggta caggatctga
    12421 agtaacacca tttgccgtta tctctgataa agcaaacaac cgtaaatacc caatcgctga
    12481 ctactcattg acaccaactg tggcaattgt agaccctgct ttggtattga cagttccagg
    12541 atttgttgct gctgatactg gtatggacgt attgactcac gcgacagaag catacgtatc
    12601 acaaatggct agtgactaca ctgatggttt agcacttcaa gctattaaat tggtctttga
    12661 aaatctcgaa agctcagtta agaatgcaga cttccactca cgtgagaaaa tgcataacgc
    12721 ttcaacaatc gctggtatgg cctttgccaa tgccttccta ggtatttctc actcaatggc
    12781 ccataagatt ggtgcgcaat tccacacaat acacggtcgt acaaatgcta tcttgcttcc
    12841 atacgttatc cgttacaacg gtacacgtcc agctaagaca gcaacatggc ctaagtacaa
    12901 ctactaccgt gcagatgaaa aataccaaga tatcgcacgc atgcttggac ttccagcttc
    12961 tactccagaa gaaggggttg aatcttacgc aaaagctgtc tacgaactcg gtgaacgtat
    13021 tgggatccaa atgaatttta gagaccaagg aattgacgaa aaagaatgga aagaacattc
    13081 tcgtgaatta gccttcctgg cttatgaaga ccaatgttca ccagctaacc cacgtcttcc
    13141 aatggtagac catatgcaag aaatcatcga agatgcatac tatggctaca aagaaagacc
    13201 aggacgccgt aaataattgt ttatcagtct agaagcaaga caaaaactca atttgaggga
    13261 aagatccagt aatttttcta tgataaaagg catcctatca aggtttttga acacctgata
    13321 ggatgccttt ttatgatatt gaggcctttt tgcccttttt gaaaaactag aatagaaaca
    13381 aaatatataa tagattgaaa ctggaatagt acacttctgc ttctaaaaca ttgttagaat
    13441 tcgatttgac tgtcctgatc gatttgtcct attcctattt cattttatta tataaaaaat
    13501 atagtatagt agactgaatc taaaatagta cgaaacaatt gctaaaacat ttatagaaat
    13561 taattttact ttcctgatag agttgttcac atcttatttc aattcactat agtttaattt
    13621 aagagtagta tttactaagg cccaattaaa atcaaagagc aaactagaaa acgagtgcca
    13681 ttcagctcaa aacactgatt tgagattgca gataagacta gccccctcat taacagattt
    13741 acgataaaac gatgacaagg tgtgttgctt tttgatttct aaagagtata atgatagatc
    13801 tctataaaat aagtgcgaag gaaatgagct tttatagtcc tttcgtttta aaatactatc
    13861 tcagatattc ttatatcgac aagaagtttt tgagtcattc cctcatcata catattaaat
    13921 aaatagtggc tcattcaatt tttcactaga ataataagct agtatagtaa actgaaataa
    13981 gatataaaca aataaattgg agcttaacat ccatttccag caatttttta gaaactacag
    14041 tggactattc tagattcaac atattataaa aactagagta aaagaaaagg attggatctt
    14101 gtgtaatgca ggatccaatc ctttcaatca ttttgtccaa cttttggagg ttcctacaat
    14161 gtagtcgtca ttaataaaga cagatgggaa tgacagtgtt cctatttatt ttgatagaga
    14221 tcgatgaatt ctttagatag caactgaata atctctgttg aagccatttg gtcttctgca
    14281 tgcataaata gcaaggagaa tcctattttt tctccagtag cttctttttg tatgagatta
    14341 gagtgaatct tgtgcgcttc tactaaggag tcttccgctt cttcaacttt aattttcgct
    14401 tcttttaaat ttcctgcctt agctagttgg atggcttcaa taaaggatga tttggctgct
    14461 ccactattgg caatgagctg aaaacagata tattccattt cttctgtcat cttatttctc
    14521 ctatccatgc aagtgcttgt tccagaactt ttgctccatt catcattccg taatcccgca
    14581 tatcaatggt atctacaggg atatttcctg caatttcttt cacagcaagt aactcataac
    14641 gaatttgtgg cccaattaga atgacatctg cttcatggat attcttttta gcttctgtca
    14701 ttgattttgc ttggatagag atttcaatcc cacgttcagt cgcactttgt tgcatttttt
    14761 taacaagcat acttgtcgac attcccgcat tacatactaa taaaatttgt ttcataatct
    14821 taaccttcca tttcttgttc aacaactttg tcattaactt tgataaatgg aatgtataga
    14881 agaactccaa gtgcaaagat gatgaattga actagaactg ctctcacgtc ccctgctgtt
    14941 gctaaccatg catttaagaa tactggtgta gtccaaggaa cttgtataaa tgcaggactc
    15001 atgaatcctg taactgttgc taagtagctg attaaaatac caaggactgg aactgtgata
    15061 aatggaatag ctaatgaaat gttataaacg attgggtaac cgaataatac tggttcattg
    15121 atattgaaga taccaggtcc aaaagataat ttagccacgt ttttagagac agcattgcga
    15181 ctcactaaga atgttgctat taataaacat aatgtagatc cactaccacc cattaaagcg
    15241 aatgtttgta tttgtgatag gttgatgatg tgtggaatgg cttgtccatt atttgctgca
    15301 gtgatgtttt cagtaatgtt aattaatagt aatggttcta ggatggcact gtaaataact
    15361 gcttggtgaa taccaaatag ccataacata tttcctaaag agtaaataat aatgaccccg
    15421 attaagcttg taccaatatg acgaattggt tcttgaataa agattgtaat gattgagatt
    15481 aagttcattc cagttatatt gaataataat gctgaaacaa ccccaaataa ggagatgacg
    15541 gtcatgactg gaagtaatac gctaaatgat ctactaacag ctggtggaat attttcacca
    15601 aggttcattt gtaaagcttt aacgtttgat aattcaatga ataattctgt tgcaataatc
    15661 gctacgataa ccccggcgaa cattgcgcct gtacctgtgt tgttgaatga aagaacacct
    15721 gaaatgttta cagcatcttt tgctccgtca ggaactacag aaactgtatt tggcatcatc
    15781 acaattaaag aaactaatgc tagcattgat gctgctaacg ggttttcgaa atctctgttt
    15841 ttagctaaga aataaccaac cattacagca ataatcatac ctgaaatact taaagtaccg
    15901 tttgcaattg ttattcccca atattggaat tttgttaatg tatccccttg gaaaatccac
    15961 ttaaataccg tgttgttcaa aagaacgatt aaacctgcca aaatatataa tggcattact
    16021 gttacgaatg catctcttag ggtttttaaa tgaatttggt tccctagttt accagcaaag
    16081 gtggcaaatt gatctataaa ttttgagttt ttcatctgaa tatctcctct ctttactcct
    16141 caatttctac ttcaaaaccg ttattgtcac ttactttgcg ataccatctt cctgagctct
    16201 tgatggttct cttttgcgtt tctaaatcaa cggagataaa tccgtaacga ttcttatatg
    16261 cattattcca agaccagcaa tcaaatgcgg tccaagcgtg gtatccaaaa cagtgacttc
    16321 cctcttcaat ggctttatgt agccatctta aatgttcttc ataaaattca atacgataca
    16381 cgtcatcgat aactccattt tcatcgataa accgtgcttc gttttcaaca cccattccgt
    16441 tttcactgat aaaccatgga atattatcat attcttcctt cacaatcata gcaatatcat
    16501 aaatggcttt cggaaaaatt tcccaaccac gatatggatt catgcgacgc tccggccatt
    16561 catactcttt gaagtattgg tctggcatcc agggcgtctg atattcctca ggatttgctt
    16621 gtgcttgaac acgttttgga tggtagtagt ttactccaag aaaatcaacc gtatttgatt
    16681 tcatcagttg aagctctttt tcggtatgac tccataacac gccatctctc tctagctgtt
    16741 ttaccaatct ttctgggaaa gttcctttaa cagctggatt caagaagact ttgttaaaga
    16801 agtcttctgt aaatcgactt gcttctaagt cttctggaga attacttctt ggataagcag
    16861 gtgtcaagtt taaaataatc ccaatctttc catcaagtcc taatgagcga tatagttgaa
    16921 tcacttttgc actagcaagg tttagattat agatgacttg tacggcctct tttccctttc
    16981 cttttagatt tggataatgg aaagcatata agtatcctgc ttctggaatg accattggct
    17041 cattgaaagt tgtccagtaa tgaaccttat ctccaaagca tgtgaaagca gtcttggcaa
    17101 acttcacgaa taactccact acatgtttgc tttcccaacc accgtatttt tgaagaagtt
    17161 ccactggtaa atcaaaatga tgtaaattca tcacaagatc catctggttc tttttagctt
    17221 cttcaatgat ggcattgtag aaagcaatac cttttggatc aggctcacct gtctctaaat
    17281 tcttgatgag tcgactccat tggatggaag tgcggaaaga attaactcca atttccttca
    17341 tcaagtggaa atcttcggtg taagtatgaa aaaagttact ggctacaaga ggtccgacat
    17401 tatcgaaaaa atcttctgga tgcgttttga accagtagtc catcacattt tcatgtactt
    17461 ttccatattg accttctgtc tgaggtccgc tagaagcagc tccccaccaa aacagattag
    17521 gaaatactaa cttttttttc atgctcaacc tcctttctat tattctatac ataaagtata
    17581 gcataatttt aaaatttgtc tagacatttt taaaaattgt tgatacatgt cttgtgtttg
    17641 cctcatttct tgaactttgt tatactacta ttagaatatt atagagagaa ccagattaaa
    17701 tgagtacaaa atatttattt atttacaatg agattcgtga aaagattctt tgtaataaat
    17761 ataccatgaa cgaacaattg cctgatgaaa tgacattagc taaacagttt gcctgtagtc
    17821 gaatgacgat caaaaaagct ttagacttgt tagtttctga gggcttaatt tttagaaaac
    17881 gtgggcaggg aacctttgtt ctctctcgtg gcagctcaaa aagaaaatta atcgttccag
    17941 aaagagatat ccggggactg acaaaaatat ctgaagatgc tcattctaca attgactcga
    18001 ggattattca cttcaaatta gaatttgcaa acgaattttt agcagaaaaa ctacaggtcg
    18061 ctttgcagag tccagtttat aatatttacc gtctgcgtat tattgacggt aaaccttatg
    18121 ttctggaaca aacttatatg agtaccgatg ttattccagg tattactgaa gatattttac
    18181 aaaaatcgat ttacaattac attgaaggaa agttaggatt gcatattgcc agtgctacaa
    18241 aaatcttgcg agcttcttct agttcagaaa atgagcaaca ttacttgcag ctccttccaa
    18301 cggaaccggt atttgaagta gaacaagtgg cttatttgga taacggaact ccgtttgagt
    18361 actcgattag tcgtcatcgc tatgatttat ttgaatttaa ttcttttgca ttacgacatt
    18421 cctcctagga gaaaatgtga aaatgaagcc aatcttttac agactctagt ttaagaaaaa
    18481 tttaaaacag ggcaagaagg tcccatctat gcttaaatgg tttctctttt ctaaataaga
    18541 tagctttaaa agagtgatcg ttttatccat catgttgaaa aatatcttcg tatagcttat
    18601 agagtaggta ctgaaattgt tcacctgatc tacttcttat agttatttag ttttaaatag
    18661 tgtttcaaac attcttacac tgacgagaag tttttgagtc ttttcttgta acacatatag
    18721 tatactgagg ttagaatagt agactgtgac ttctaaaaaa ttgctagaaa tgaatttcaa
    18781 tctcccaatt tatttgttca tatcttcttt taatatatta aataaattct gaatcataat
    18841 catttaaaaa aattttattt tttatttttc attacgaata atatagatga aggggaaaga
    18901 gtatgaaaac agaactgttt cttttgctat tagttcaaaa ggagaaaaaa tgaaagtaga
    18961 aaatatttcg tatagggtgg atcatcgtat attgtttgat aatatttctt ttgatacttc
    19021 gagttcaggc gtgacattaa ttactggtaa aaatggtaca ggaaagtcaa ctttactata
    19081 gtagattgaa actagaatag tacacatcta cttctaaaat attgttagaa atcgatttga
    19141 ctatcctgat ctatttgtcc tgttcttatt tcatttcact acatctcaaa ttgagtatga
    19201 cgaagtgcgc tcccatgtcc tgggaacgca ctttcttcat atttttcata ttcttgaatc
    19261 catcgataaa gactattggg atgaattttt aaagttgaac taatcatttt tacaggatga
    19321 ggtttacagc agagagtttg aaggctttat caaaggtttt tcttggcata atgacttttc
    19381 ctcgtttcca cttaattttg tgtctacttt attataccaa gtccaccctt aagttagata
    19441 ataaatctaa cttaaggaag ctagaaggat gagaatccag gtggtcaaga gtcccaaact
    19501 taagctgatg gggacaccca gaataatttg ctttttgaag gcaaggccac gttcctctat
    19561 attgggaagt gagagttgaa tgagagaacc agctgatgaa aagggtgaga tattagtaga
    19621 tagagcgcca ataacggtgg ctgttgtgag taagtgaata tcaatctggg gattttgagc
    19681 actgatgata gcaatgatgg gaaagagggc tggagctaca acggataggg tggaactaaa
    19741 gagtgacatc actccggcta tcacacaaaa gaacagaggt aaccagaaat gaggaatgga
    19801 tgttgtcatg aggtgcccta tcagtgtgac taaacctgac ttgaccgcta gagacattag
    19861 taagctcatg ccgcagagca tgataattgt agcccaggga accttagcta aaatggcttc
    19921 ttgcttccct aatttgagcc ttaaggcgag gcagaccatg agtattgaga caaagccaat
    19981 atcaaatgtt ttttgataag tagctatcca ggcgatgttt gggaaaatga gatgcaacaa
    20041 gggaaaaagc caaaccaaaa ccatgctgct gatcatgagc aaggtggttt gtctttgaac
    20101 cttgctgagg agtggtggtt ggtcaatagt caaggatgag tttgtttttc ccttactata
    20161 gtgactgtaa caggataata aaagcaagac gatgagtggg tagataatgc tgacgataaa
    20221 gatatgattg ccaagtgaaa aagcttgctc ttcccatccc atttgcttaa acaggccttg
    20281 aaagacaatg cctgagctac tggttatcaa attagcccct cctgaagctc cccaattgac
    20341 ggcttgagct ccaatcaaag ggtgtttgtc cgctttttga cagagggtaa tcgctagagg
    20401 acagcaaacg gccatagtag tgaaaaatcc agcacctaaa gcagacaaaa gggttgccat
    20461 caggtataaa atcatgtaga gggcgttagg gtaggtgcgt gtgcggtaga gaatgtgttg
    20521 agccaaaaca tcaagagtac cgttagttat tgcaaagtta taaaagagag agacgctaaa
    20581 aatggtaaaa aagagtgagg ttggccaaaa atgaagaagt tctttggggc ttaatcccat
    20641 gagagtggtt gcgatgaggt aagaaaaagc aatagccagc aggccaatat tgattttggt
    20701 gcggtaacca attccaatgg ctagagcaat ggcgctaatc attattaaat gaatcattga
    20761 attgtccttt cagttagaat atggaaatag gttggcaatt ttggcgctca aaagaccacc
    20821 tgtttcctat tggtacttga ctattataca caaaaaaaat acaattgtct tgacaattgt
    20881 attgacactt gttagaatta aaaatgaggt attcaggctt gtgatttcct atggaagtta
    20941 atagtgattg cctctaatgc ttacaagtga tattaaaaat agaggactta gtgatgtcaa
    21001 tcatttcaac tgatttaacc ccttttcaaa tagatgatac attgaaagca gccttgcgag
    21061 aagatgttca ttccgaagat tacagtacca atgccatttt tgatcatcat ggccaagcca
    21121 aggtgtcgct ttttgccaag gaagctggtg ttttagcggg gctaaccgtt tttaaaaggg
    21181 tttttaccct atttgatgcc gaggtgacct tccagaatcc tcatcaattt aaggatgggg
    21241 atcgtttgac tagtggcgat ttggttttag aaatcatagg ctcggtgaga agtctcttaa
    21301 catgtgaacg cgttgccttg aattttttac aacatttatc agggattgct tcgatgacag
    21361 ctgcttatgt agaagcctta gacgatgatt gcattaaggt atttgatact cgaaaaacta
    21421 ctcctaattt acgtcttttt gagaaatatg ccgtgagagt tggcggtggc tataatcatc
    21481 gctttaattt atcagatgct atcatgctaa aagacaatca cattgcggca gtaggtagtg
    21541 ttcaaaaggc aattgctcaa gcgcgtgcct atgctccttt tgtgaaaatg gtcgaggtgg
    21601 aagtggaaag ccttgctgct gccgaagaag ctgcggcggc gggtgctgat attatcatgt
    21661 tggataatat gtcattggaa cagattgaac aggccattac cctaattgca ggacgttctc
    21721 ggattgaatg ttctggaaat attgatatga ccactattag ccgttttcgt ggtttagcga
    21781 ttgattacgt ctccagtggt agtttaaccc atagtgctaa gagtcttgat ttttccatga
    21841 aggggttaac ctaccttgat gtctaagttg taaaataaac taacttttta aaggatgtct
    21901 ttcctctaga acgagtttta tgtcagatag tttaaacgcc tcttcaa
//
LOCUS       DAVHLA010000035        21327 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVHLA010000035 DAVHLA010000000
VERSION     DAVHLA010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21327
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.035"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            <1..372
                     /locus_tag="VVO77_001544"
     CDS             <1..372
                     /locus_tag="VVO77_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEU5693534.1"
                     /translation="KVSGRRYQRISLVAGLTNGELIVPMTYEETMTSDFFEAWFQKFF
                     LPTLTTPSVIIMDNARFHRMGKLELLCEEFGYKLLPLPPYSPEYNPIEKTWAHIKKHL
                     KKVLPSCNTFYEALLSCSCFN"
     gene            338..718
                     /locus_tag="VVO77_001545"
     CDS             338..718
                     /locus_tag="VVO77_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU5693535.1"
                     /translation="MRLFCLVLVSIDYINCLSETTDKNWHKSDRVFVTNTGKTVHSSI
                     LSKSLQRANERLKKPIPKHLSPHIFRHTTISILSENKIPLKTITDRVGHSDSEVTTSI
                     YTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(856..2160)
                     /gene="eno"
                     /locus_tag="VVO77_001546"
     CDS             complement(856..2160)
                     /gene="eno"
                     /locus_tag="VVO77_001546"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEU5693536.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            2324..2770
                     /locus_tag="VVO77_001547"
     CDS             2324..2770
                     /locus_tag="VVO77_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEU5693537.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(2767..3882)
                     /locus_tag="VVO77_001548"
     CDS             complement(2767..3882)
                     /locus_tag="VVO77_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEU5693538.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASDQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(3891..4220)
                     /locus_tag="VVO77_001549"
     CDS             complement(3891..4220)
                     /locus_tag="VVO77_001549"
                     /inference="COORDINATES: protein motif:HMM:NF012905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HEU5693539.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAELGIAFCSKEMLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            complement(4165..4536)
                     /locus_tag="VVO77_001550"
     CDS             complement(4165..4536)
                     /locus_tag="VVO77_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HEU5693540.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            complement(4595..6028)
                     /gene="glgA"
                     /locus_tag="VVO77_001551"
     CDS             complement(4595..6028)
                     /gene="glgA"
                     /locus_tag="VVO77_001551"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEU5693541.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHIHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGLERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWLAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(6025..7164)
                     /gene="glgD"
                     /locus_tag="VVO77_001552"
     CDS             complement(6025..7164)
                     /gene="glgD"
                     /locus_tag="VVO77_001552"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEU5693542.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPKK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(7154..8296)
                     /locus_tag="VVO77_001553"
     CDS             complement(7154..8296)
                     /locus_tag="VVO77_001553"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEU5693543.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(8286..10214)
                     /gene="glgB"
                     /locus_tag="VVO77_001554"
     CDS             complement(8286..10214)
                     /gene="glgB"
                     /locus_tag="VVO77_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEU5693544.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPNVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLICIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
     gene            complement(10679..12103)
                     /locus_tag="VVO77_001555"
     CDS             complement(10679..12103)
                     /locus_tag="VVO77_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEU5693545.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEKIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMLKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVTWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(12648..14927)
                     /gene="pulA"
                     /locus_tag="VVO77_001556"
     CDS             complement(12648..14927)
                     /gene="pulA"
                     /locus_tag="VVO77_001556"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEU5693546.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(15039..16997)
                     /gene="ligA"
                     /locus_tag="VVO77_001557"
     CDS             complement(15039..16997)
                     /gene="ligA"
                     /locus_tag="VVO77_001557"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEU5693547.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KVSQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSISKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(17090..18268)
                     /locus_tag="VVO77_001558"
     CDS             complement(17090..18268)
                     /locus_tag="VVO77_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU5693548.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(18348..19211)
                     /locus_tag="VVO77_001559"
     CDS             complement(18348..19211)
                     /locus_tag="VVO77_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEU5693549.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISSHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAIHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(19214..21115)
                     /locus_tag="VVO77_001560"
     CDS             complement(19214..21115)
                     /locus_tag="VVO77_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU5693550.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNDLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETISWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENAAV
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSEQV"
BASE COUNT         6442 a         4680 c         3779 g         6426 t
ORIGIN      
        1 aaagtatctg gaagaagata tcagaggatt tctttggttg caggtctaac aaatggtgag
       61 ttaatcgttc caatgactta cgaagagacg atgacgagcg acttttttga agcttggttt
      121 cagaagtttt tcttaccaac attaaccaca ccatcggtta ttattatgga taatgcaaga
      181 ttccatagaa tgggtaagtt agaactcttg tgtgaagagt ttgggtataa acttttacct
      241 cttcctccct actcacctga gtacaatcct attgagaaaa catgggctca tatcaaaaag
      301 cacctcaaaa aggtattacc aagttgcaat accttttatg aggctctttt gtcttgttct
      361 tgtttcaatt gactatataa attgtctaag cgaaacaacc gataagaatt ggcacaaaag
      421 cgaccgtgtt tttgttacca atacaggaaa aacagttcat agttctatct tgagcaagtc
      481 tctccagcga gcaaacgaac gccttaaaaa accaattccc aaacatctgt cccctcacat
      541 cttcagacac accactatta gcatcttatc agaaaataaa attcctttaa aaacaatcac
      601 ggacagggtt ggtcattccg actctgaagt cactacttcc atctacaccc acgtcacaaa
      661 gaacatgaaa gatgaagcaa tcaatgtact ggataaagtt atgaaaaaga ttttttaaaa
      721 agttttgccc cttttttgtc ctctaaatac aaaaatagcc cttcggataa aatccgaggg
      781 gctagaaacg ttgttaaatc aacggccgaa cttttgaatt tcatggttcg ggataaaata
      841 gttcactgaa ctattttatt ttttaaggtt gtagaatgat ttcaatccac gatattcagc
      901 tacttcacca agttggtctt cgatacgaag caattggttg tatttagcga tacggtctgt
      961 acgtgaaagt gaaccagtct tgatttgtcc tgcgttagtt gcaactgcaa tatcagcgat
     1021 tgttgaatct tcagtttcac ctgaacggtg tgatacaaca gcagtgtaac cagcttcttt
     1081 agccatttcg atagcttcaa aagtttcagt aagagtaccg atttggttaa ctttgataag
     1141 gattgagtta gcagcacctt cttggatacc acgtgcaagg tagtcagtgt ttgttacgaa
     1201 gaagtcgtca ccaacaagtt gtactttctt accaagacgt tcagtaagag ctttccaacc
     1261 atcccagtcg ttttcatcca taccatcttc aatagtgatg attgggtatt tgttaaccaa
     1321 ttcttcaagg tagtcgattt gttctgcaga tgtacgaaca gcagcacctt caccttcaaa
     1381 tttagtgtag tcgtaaactt tacgttcttt atcgtagaat tctgatgaag cacagtcaaa
     1441 tccgataaat acgtctttac ctggtacata tccagcagct tcaatcgcag caaggatagt
     1501 ttcaacacca tcttcagttc cttcgaaacg aggagcgaat ccaccttcgt cacctacggc
     1561 agtttccaaa ccacgtgatt taaggatttt cttaagagcg tggaagattt cagcaccgta
     1621 acgaagggct tctttaaatg ttggcgcacc aactggcaag atcatgaact cttggaaagc
     1681 gattggagcg tcagagtgag aaccaccgtt gatgatgttc atcattggag ttggaagaac
     1741 tttagtgttg aatccaccaa ggtagctgta aagtgggatt tcaaggtagt cagcagcagc
     1801 acgagctaca gcgatagaca caccgaggat tgcattcgca cccaatttac ctttgttagg
     1861 agtaccgtca agtgcgatca tagcacggtc aatagcttgt tgatcacgta catcgtagcc
     1921 aatgatagct tcagcaatga tgttgtttac gttgtcaaca gctttttgtg taccaagacc
     1981 accgtaacga gatttgtcac cgtcgcgaag ttcaactgct tcgtgttcac cagtagaagc
     2041 tcctgatgga accataccac gtccgaaagc acctgattca gtgtaaactt ctacttcaag
     2101 tgttgggtta ccgcgtgagt ctaggacttc gcgagcgtaa acatcagtaa taattgacat
     2161 tttttactct ccttatgagt taaatttttt acacctctat aataccttaa aacccctcct
     2221 ttttcaagaa aaaacgttat ctttgtgcaa cttttcctta actttataaa gtaatcgctt
     2281 tcttttgtct gttttattct aacttttatg atatactgtt ttcatgacag atttatcaaa
     2341 acaattactt gaaaaagctc atggtgggtt aaaaataaat ccggatgaac aaagacgcta
     2401 tcttggtact tttgaggaaa gagttcttgg atatgtagat attgacacag caaatagccc
     2461 tcagttagaa aaaggctttt tatttatttt agaaaacctt caggaaaaag cagagccact
     2521 atttgtgaag atttcaccaa ctatcgaatt tgataagcaa gttttctact taaaagaagc
     2581 aaaagaaact gatagtcaag ccaccatagt atctgaagag catattactt ctccttttgg
     2641 cctggttatt catagcaatg caccagttca agtagaagaa aaagaccttc gacttgcttt
     2701 tccaaaactt tgggaagtta aaaaggaaga accagccaaa acatccttat ggaagaaatg
     2761 gtttagctaa atcttgcaca tatttaataa gtgcccaata ttggcagccg tgcgctccag
     2821 atagagactg gcatttttca aactatcttc taaaggttca cttttctcca aaatagaaaa
     2881 gacagcttgg atattttcaa atggtagggg aggtaaatct tcagcaagac taccgcaaat
     2941 agcaataaca ggaactccaa caggggttct ttttgcaaca cctataggcg ctttcccagc
     3001 aaagctttga ctatcaagtc ttccttctcc aacaacaacc aagtcagcat ctgaaacttt
     3061 cttatcaaag ttgattaagt ccaagcaggt atcaattcca gacacgatac ttgcctgagc
     3121 aaaggcacac aaaccaccag caaggcctcc acctgctcct gctcctttaa tttctaatgt
     3181 tgcaggtgag aatttttcat aaaaatcttg gatcgcctga tctacgactg caaacatagt
     3241 cggatgtaga cctttttgat tgccaaaagt gtaagtcgca ccttgatgac cacataaggg
     3301 actcacgaca tctgctagaa tatgaatttg aacaccttca ggaattttat agcaattttc
     3361 tgttgaaaca gaagctaagt ttaataagga ttgatcggaa gcaggcaaga catttccatc
     3421 cctatcataa aattgataac ctaaaccagc agcaatcccc agtcctccat cattactggc
     3481 cgtgccacca acaccgatat aaatatcttt aatcccttta gaaatgagat ggagaatcaa
     3541 ctctccaata ccacaagttt ggatttgaag tggatttcgt ttctctagcg gaatttttcc
     3601 aagaccaacc aagtcagcta cttcaaatag tgccagttcc cctttttgaa aatagcgcat
     3661 ggcttctttt tgtccaaaag ggtctgtcac ttggatccat ttttctttta ggtcaagaga
     3721 atgtcggata gcatctacag taccttctcc cccatcacca acagggcaga ggagacattc
     3781 tacatctgct atcgattgtt ggaagcctct ttttattgct tcagctacct gttgagctgt
     3841 caagctttcc ttaaacgaat ccggtgcaat tacaatcttc atattttccc tcattctaaa
     3901 cagtcaatca aaggaagaac ttctaaaaaa tccctcttgt caacatgatg tggtatttct
     3961 tttttgagca tttctttgga acaaaaggcg attcctaact ccgccgactt caacattaat
     4021 agattattga ccccatcacc gattgccacc gttctttctt tagaaagttt tagtttcttt
     4081 ctccattttt ccagagtttc ttttttgacc tggggactta taatttgtcc aactaatttt
     4141 cctgttaaaa gaccttcttt gacttcaagc tggttggcag tgaaataggc aataccaagg
     4201 gattttgcta atctctccaa ctattggtgt aaatccacca gacaccagac caactaggat
     4261 gccattcttt tggagaatag agatgaactc tgggacattt agcgatagat gaattgagtt
     4321 gaagacgtta tcaaagacca aaataggaag accttccaac aaggacactc tttttcttaa
     4381 actgctttca aagaccaact ctcctcgcat tgctcgactt gtaatctgcg aaatttccgc
     4441 ctcatgacct gcctctctcc ctaaaagatc aatcacttct tctaggatta aggttccatc
     4501 tacatccaaa acacacaagc cttttacttg agacatcagt tctcctctct aaacagccta
     4561 aaaatcgtat gaagtcatca tacgatttta tctattaatt aactaaacta tggtacaagt
     4621 caaggtatga cttgcaggct gtatcccatg agaagtcact ctccatagct tgtttttgta
     4681 ggtttctcca aatgtctgga tggtttctat acaagtccaa tgctgtttgg aaagtccaat
     4741 ttaaccaata aggagataga ttgtcaaagc taaagccagt accgcttcct tcgattggat
     4801 tgaaagcgcg aactgtatct cgcaagcctc caacttcatg gaccaatggc aaggttccat
     4861 aacgcatagc catcatttga gacaagccac acggttcaaa acgacttggc atgaggaaga
     4921 ggtcacaagc agcgtagatt tcctgagcaa gtttgacatc aaaagtgata tttgttgata
     4981 gcttgtctgg gtaaatctga gccaaccatg agaaagctcc ttcaaaggct ggatcgccag
     5041 ttcccaaaag aacaatctga acatcttctt gcaagatatg gtgaagactt tcgaccacca
     5101 catcaaaacc tttttgacgt gtcaaacgag aaacaattcc caccagtgga acgtctgctc
     5161 taacaggcaa gccaactctt tcttgcaatt ttgccttatt tttggctttc ccagacaaat
     5221 cttcctgatt gaaatgatag tctaaaagag catccgtctg aggattataa agatcagcat
     5281 caatcccatt cacgatacca gatactttac cagactccat tttaagaatc tgatccaaat
     5341 tacatccaaa ctgactagtc ataatttcat gagcatagct aggtgaaacg gttgaaacac
     5401 ggttcgcata gagaatacct gccttcatcc agttcagaca gttgttccat cgaagggtgc
     5461 catcagcgta acgttcaagg ccaactccaa acaaatcacc caacattcct tctgaaaatt
     5521 gtccttggaa ttctaaatta tgaatggtta aaactgtttc aatgtcctca taggcttgaa
     5581 tccaacggta tttttccttc aacaagaaag gaatcatagc tgtatggtag tcatgaatat
     5641 ggagaagatc aggaataaag tcaatccttt ccatagcctc aatggcagcc agttggaaaa
     5701 aggcaaagcg ttctccgtca tcaaaatcac cgtaaacatg accacggaag aaataatatt
     5761 gattgtcaat aaagtagaag gttacaccat ttaatactgt tttcttaatt ccacaatact
     5821 gtctgcgcca accaacgctc acctcaaaat gaagcacatc ttcaatctga tttccaaatt
     5881 tagcctctac catatcatag tagggtaaaa tcactgcaac ttcgtgccca gcttttacca
     5941 gtgattttgg aagagcgcca atgacgtctc ccaaaccacc tgtttttgaa aagggtgcac
     6001 cctctgctgc tacaaataaa attttcatga atgaatatcc tctgttactt tagcaccttt
     6061 cttaaccaca actggatgtt ctgcagttcc tcgaatcaca acaccaggct caacttcaac
     6121 ccctttgtcc aagatagcat attcgacctg agccccttct ccaataacaa cacgagggaa
     6181 gagcaggcta tctttaacca agctatcctt atggacatga atattacgtg atagaacaga
     6241 attagctact tgaccttcaa taatactacc agaggcaaac tgagaagtgc ttaccttaga
     6301 tgtattagca tagtaagttg gctcttcgtt tttgaccttt gtataaatct tttggtttgg
     6361 tgagaaaaga gaatagaatt tttgtgattc aagcatatcg atattcgctt gataataaga
     6421 tttaacagag tgaatattgg ctagatagcc cgtgtactcg taggcgaaag ctccctcttt
     6481 tacagccaaa tcccgtaaaa catagcgcaa tttctttgga tgttcttttt tagcttcttc
     6541 ttccaagtgt tcaatcaacc aaggtgtatc aacgacaaag atatctgtag acatattgaa
     6601 cgtttcagct gttgacttgc tatcaaagag tttatgagaa agaacatggt ctgtttcatc
     6661 tacatccaag attgcattta cttctgaaat atctttctta gctagttttt tataaactac
     6721 agtgataggc tcttttgttg tactatgtag gtggaaaact tggttcaaat caatgttaat
     6781 aagaacatcg cagttgaggg caaccgtttg gtttgagcca gaacgtttca aataagtaag
     6841 aagctgttgg tagtattctt ttccaactgt actactttct acacgggtat tgtaaattcc
     6901 tagatagtaa tgactaagaa gggttgataa gccccactcg cgtcctgaac gaatatggtc
     6961 aaatactgag ctgatattat cctgctggaa aataccaaag acactacgaa cacctgcatt
     7021 agcaaggctt gaaagtggga agtcaatcaa acgatatttc ccaccaaatg gcaaacttgc
     7081 tactggacgg tggtccgtca atgtcgacat attgtgaaaa ccaactgtat ttcctaaaat
     7141 ggcagaatat ttatcaatct tcatctgttg ctacccccac tacttcatta tatcctacaa
     7201 cttgtacttc atctgttcca tcaatttcga caccgtcaga aataatcgca ccttcaccaa
     7261 taatggcacg tttaatctta gctccttgac caatgatagc tccactcatg ataactgaat
     7321 caaggacttc cgctccttcg cgaacttgcg cgcctgttga aaggatagaa tgtttaacag
     7381 ttccatcaac gaaacatccg tctacaacta atgagtcttc cacatgagca tttgccccga
     7441 ggaagtttgg tggtgaaatc aagtttcttg agtaaatctt ccattgacgg ttacgactat
     7501 ccaaggcatt ttctggagaa atatactcca tgttcgcttc ccaaagtgac tcaatagtac
     7561 caacatcttt ccaataacca ctaaattcgt aagcataaac actttcacct gactcaaggt
     7621 aatttggaat gacatttttc ccaaagtctg acatgccaac cttgctcttt tcagcagcga
     7681 ctaacatatt acgaaggcgt tgccaatcaa aaatgtagat tcccatagaa gcttttgtag
     7741 atttaggttg agctggtttt tcttcaaatt caacaatacg attgttagca tctgtgttca
     7801 tgataccaaa acggcttgct tctttaagag ggacgtctaa aactgctact gtcaagctgg
     7861 cattattatc cttatgagac tggagcatat catcatagtc cattttgtag atgtgatccc
     7921 cagacaaaat caagacatac tcaggattga cactgtcgat atagtcgata ttttggtaaa
     7981 tagcgtgact agtcccctca aaccaacgat ttccttcact tgcagaataa ggttgaagaa
     8041 tagagacacc tgaattgata ccgtctagtc cccagcttga accattccca atatggttgt
     8101 tgagagcaag tggttgatac tgtgtaacga ccccaacatt atgaatccct gagttggcac
     8161 agtttgatag ggcaaagtca atgatacggt agcgcccacc aaattgcaca gctggttttg
     8221 cgatgctttg agtgagttta ccgagacgag ttccttgccc accagcaaga atcaaagcta
     8281 acatttcatt tttcattttc tactcctttt tggtttttat ttgtgacggt tttagtagat
     8341 ttcaagcgac gtttgatttt ccatacactt gctcccatag ccggtagagt aaaggttaag
     8401 gtctgctcat aatctttcca tagtccttct tgcgtttgaa cagtttgatt atgttctttc
     8461 caaacgcctc cccactcttc caactcagta ttccatactt cttcgtaaat tcctgcaacg
     8521 ggtagtccga ttgtaaaatc tttccgctca acaggtacca tgttaaagat acagattaac
     8581 atttctccct ttttaccctt acgaataaag gaaagaacac tctggtctcg attatccgca
     8641 tcaatgattt caataccatc atagctggta tcgatttccc acagacagcg atgatctttg
     8701 taaaactggt ttagctgaga agtgaaatac ttcatcttag cattcattgg gtcttctagg
     8761 ttagaccatt ccaactgttc ttcagatttc cattctagga attgaccgta ttcgctaccc
     8821 atgaagagca atttcttacc agggtgacaa atttggtacg tatagagatt gcgcaagcct
     8881 gcgaattgat tgtaacgatc tccccacatc ttatgcatca tactcttctt gccatgaacc
     8941 acttcatcgt gcgagaatgg caagagataa ttctccttga aaacatacat aaagctgaaa
     9001 gtcaccaggt taaagtcata tttacgatag atcggatctt cttcgtagaa acggaggata
     9061 tcattcatcc agcccatgtt ccatttgtag tcaaatccta gaccaccaat ctctttcatt
     9121 cccgtaatct tggtcgcaga cgaactttct tctgcaatca tcatcacatt tggatattct
     9181 aacttaataa cctcattcaa gcgctgaagg aaataataac cttcatagtt gagatttccg
     9241 ccatctttat taggtgtcca tggagcatca tcatagtcca aatagagcat gttgctaaca
     9301 gcatccacac gaataccatc caaatgatag acatcaatcc aatgcttaat gcaagaaatt
     9361 aagaaggact ggacttcatt ttttccaagg tcaaaattaa gggcacccca accatggtta
     9421 tgagccttat tatggtcttg gtattcaaaa gtcggtgtcc catcataata ggctaaggca
     9481 tcatcgttga tggtaaagtg acctggtacc cagtccacaa taaccccaat attatgggta
     9541 tgacactcct cgacaaaatc ttgaaactcc tctggtcggc cataagcatg ctctaaagcg
     9601 aagtaaccca taagctgata cccccaactc aagcccaaag gatgggacat caagggcata
     9661 aactcaatat gagtatagtt catttcaacg agataaggaa tgagttcatc cttgagctgg
     9721 gcaaaactat aaggactgcc atcagaattt cttttccatg atccagcgtg aacttcataa
     9781 atattgacag gacgctcttc aaagccccaa cgttttcttc gtgccagcca aagtccatcc
     9841 ttccatttct tctcaggaag ctctgttaag attgcccctg ttcctggacg agcctcatac
     9901 ctgacagcaa aagggtcaat cttcatcagt tgatgaccat tttgacgtgt gacatgatat
     9961 ttgtaaatat gcccttcttg agccatattg gtaaagactt cccagacccc aaaatcattt
    10021 cttaccattg gaatctgatt ttcaatccag ttggtaaaat caccaaccaa gtgaacagcc
    10081 tgagcattag gtgcccaaac acggaaggta tagccatgct ctccatttag ttcttcccta
    10141 tgtgctccta gataatgttg gagataaaaa ttttcacccg tcataaaggt ttttaatgct
    10201 tctctattat ccatatactc cccttctcct gtaagcgttt tctatgtttt tattatacta
    10261 cctttttaga gaagattcaa gtaaattact atacttcttt aattattttg aaaatctaca
    10321 acaagttcac ttactcgttc aattgtaaat caatattttt tcaaaaaatt gcgaaaacgc
    10381 ctttcttttt ctactatagt gaaatgaaat aaaacatgcg caaatcgatt aaggacttta
    10441 atctaatttc taacaatgtc ttagaaatca aagtgtacta ttttaactcc aatgtattat
    10501 atatagtaaa atgaaataat aacaggaaaa atcgatttct aacaatattt tagaagtaga
    10561 gctgtactat tctagtttca atatactata ataccaaaaa gttcgtattt tttctataat
    10621 tattattatt ttatagcaaa aaaataaaac caggaaaaca atttcctgat tttacacgtt
    10681 atttcacatc aaaaacaatg gatttgacat ttgtcatcgc ttcaatgcta tatttaattc
    10741 cttgcactcc agctccagaa cctttgacac caaggaatgg gaaattatct ggaccacgct
    10801 gggttttatt attaatgtgg actgtaccta cttcaagttt ttcagcaatt tcaaaggctt
    10861 ttttgaaatc atttgtaaag actgatgatt gaaggccgaa ttcagattcg ttggcaaagg
    10921 caatagcttc ctctacacta gccacacgaa tgattggtaa aacaggacca aatggctctt
    10981 cccatgtcac tttcatatct tttgtaactt ggtcaaaaag cactggccag aggagattgc
    11041 cctcacgttt gattggtgta agagcctgag cctctttttc ttgtgcatcc tcaatcaagc
    11101 cccaaatgaa gtcggctgaa gcattgtcaa taacaggtgt aatatcagca ttgtcaaatg
    11161 gatcaccaac tgttaattta gaaacttctt cctgaagcaa agtagctaat ttatctgcta
    11221 cactttcgag aacaatgaca cgtttaatgg ccgtgcaacg ttgtcctgag tagctaaagg
    11281 ctcccgcaac aatttgcttg gcagcatgtt ccaaatctgc atcttctagt acaagagctg
    11341 catctttccc accaagttcc aacatgatag gacgcatacc agctaaacga ccaatacgtt
    11401 ctccaatagg agttgaacct gtaaagttga tgaagttgac ttctttgtgc tcaatgatat
    11461 aatccccaat ttctgaacca cgacctgtaa tggtgttgaa aacacctgcc ggaatccctg
    11521 cttcttcaaa tgctttagcc aacaagagtc cagaaatgga accttgtgtt ggtggcttca
    11581 acatgaccac attccctgca atcaaggcag gtgcaatttt agaagcagat aaattaactg
    11641 gataattaaa gggagcaatc gctagcacga taccaactgg ttcacgacgg acaacagcca
    11701 gtttgttttt acttgctgcc tcaaaaccac caccttccat tgcttgtcca gtgatacgga
    11761 gaccttcctc agcagcataa cgaatcaagt ctgctgtacg cactacttct ccaattgctg
    11821 ctttaatccc ttttgctact tctttggcaa ggatagtacc aattttttcc ttatcgcgtt
    11881 ctaaaatagc tgctgtttta tgcaaataag ccgcacgttc aattgctgat aaagctcgcc
    11941 atgctggcag ggctgcacgc gcagcttgca tagcctcatc agcttcagtc tgagtcatgg
    12001 ctggaactgt acccaattct tcttgattga ttggtgaata aatcgtaatt tcttgttcag
    12061 atgatttcca ttttccattt actaaattct gatatcttgt caaattcttg tcctcctgaa
    12121 aatgattaag atatatttta ccaaattttc agaaaatcac aacccttttt gcaaaatttt
    12181 tgagattatt ttcacaatct tgatttttca aagtatactc aataaaaatt aaaaaaatcc
    12241 actacgtcaa ggcgaggcta atgtggtttg aagaaatttt cgaagagcat gaatgagtat
    12301 catctatagt aaaataaaaa aactgaacaa tttggttggg gacagccaaa ccaatttctc
    12361 acaatgtttc agaaacaagg gtgtgctatt ccaatttcag cctactataa ctgtcataga
    12421 ttgctgaaac aaagtctagg taaaagtctt cataataaaa agacctccta tcaagtgttc
    12481 aaaaactttg ataggaggtc ttgttttgtg aaaatattta tcaaattttc tatacaagtg
    12541 agctgttagc caggttcttt ctattctttc aatttcaatg aatggatttt ttactaatac
    12601 tcataactgg gaatttgtct gtgtaaaaat agcgagatag atggtattta taaaacactc
    12661 aagacagcta gactaatatc atttaaaaca ttatcttctt ttgagcgact gttggttacc
    12721 aacatagcta aatttcctgc attttcaaat tgatagggtt ctgatttagc attcacaact
    12781 accaagaggt gttctttgcc gtgaacttca tagataaggc agccgctatg ttcaatcgca
    12841 gaatgcacaa agacatgatg gtaaatttca tcatagctag agtaagaaaa ggcaccagtt
    12901 tttgtcttca atcggatgac ttgacggata aactcaatac tgtcttgacg ctcattaatc
    12961 aagttccagt tcacttggtt cacactgtca ggagcattat agctattcat cgcacgctct
    13021 ctatcatcat gggtcaactc accattttca ccagtcgcaa ccagtttggt acgaccaaat
    13081 tcttgaccga tttccataaa ggccatcccc tgcatgagca gattcatggc tgtggcagtt
    13141 tcgaccttgc gcatgatttg ctctgaactt tggtctggat gaagggttgc caataaatcg
    13201 tgaagattgt aattgtcatg ggcttctaca tagttaagca cctgatttgg atgtgtatag
    13261 cttcctaatt cacgacttcc taggattgct ttagctagaa ttggctctgt cgcagcacca
    13321 ctgacaaaac ctgacttgat agcaccataa acttctcccc ctttgacagc atcgcgctga
    13381 ttgtcattaa agaaaccaat atttggcatc tggtaggcat tgtccttctt ggccttatca
    13441 taaggggcaa gacctgttcc catatcccat ccttctccat agaggataat gttggagtcg
    13501 atttcatcca agctttgacg aatcatctgc atggtcttga catcatgaat ccccatcaag
    13561 tcaaaacgga agccgtcaat attatattcc tgcacccagt atagaagaga atcaatcata
    13621 tacttgcgaa acatttcgtg ttcactggct gtttcatttc caacacccgt tccattctgg
    13681 aaggtaccat ctggattcat acgataatag taatcaggga ctgttgtttg gaatggtgca
    13741 tcaacaactg agaaggtatg gttatagact acatccataa tgactccaat acccgcatcg
    13801 tgataagctt gaaccatcac cttcaaatca cgaatgacct gagctggatc atctggatta
    13861 gttgaaaaac tagtttctgg cgcgttatag ttttgtggat cataacccca gttgtaggtt
    13921 acatttccat cctcatcgta ttctttatga cggtctgcaa ttggttgcaa ttgaacataa
    13981 ttgtagccca gcttcttgat gtaatcaaaa gcagttgact ggccgtattg gttaactgtt
    14041 ccagcctgag cagcacccaa gaaagttcct cgaagatgtt catctacacc cgatgtaggt
    14101 gatttagtca aatcacgaat gtgcatttca cagataactg ccttacatgg attttccaag
    14161 cgccaagtag cctccgaacc gtgcttaacc tcgaagtttt caacttgctt ttctacatgg
    14221 ctcagaatag ctgaacgttt gccatcaggg ctggtcgcga ttgtataagg atcacgtgtc
    14281 agtgtttggt gatgagggaa ttggacttga tactgataag tcttacctac caaatcttct
    14341 tcaacatcca aactccagac accgattgta ttgtccttat gattataaga gtagctattg
    14401 cctcttttca tctcaaaagt cttccaaacg ggtgcatcat tagcagctga ttcataaacg
    14461 acaacttgca cttctgtcgc tgtaggtgac cagagagaaa aatgagcctg attgtcctct
    14521 acacggcaac ccaattctcc ttggtaaccc caatgatgat caaaactagc actgttaatg
    14581 gccttatcaa aggcaaaagg attttgattt ttatagaaag gactggcaat agcaggattt
    14641 tcagagtaat aaatcctatc atcgccttcc aaaatccaga cctctgttaa taggggatag
    14701 tgattaaaac ggatagaata ttctttacta gtttgacctg tatgaaccac aaaattcaag
    14761 ctttctataa catgtgaact tgggtgttca aagctaaata aagctccaaa ataatcttct
    14821 ttgtaggtta gcaaatcaat tcgttgatcc tgacttttta caaaggagca agtgtcatat
    14881 tctccattct tacgatggta atgaatgcgc atagggtagt tatacatttt ttatttttcc
    14941 tttttacttt gtttctattt cactaataaa tttttgtcaa tctcgtctca attaacagac
    15001 atagtcatat tctctaaact ctgtttttaa acgatccatt acaaactttc tagccatgcc
    15061 tcatctctga cctggatacc aagttcttgt gctttttgca gtttacttcc agcgtctgca
    15121 cctaccacga cgaggtcggt ctttttagaa atactacctg tcactttggc acccagactt
    15181 tcgagtttac ttttagcttc tgagcgcttg agtcgttcca attttcctgt caataccacg
    15241 gtcaaacctg acaaggccgc atccgctact accgtctgtc ctttatagtc cagattgacc
    15301 ccagtttctt tcaattctct gagcagaatt tcagagcctt ctgtcgcaaa ataagtctga
    15361 agacttttgg caatcacgcc acctagactt tcaatactag ccacttcctc tgaatctgcc
    15421 tgagacagat tttcaattga atggaaatat tgaagtaaaa gctgactaac cttgcttccg
    15481 acatgacgaa ttcccaaacc aaataagagc ttctcggcag agttttcctt tgatgcttgg
    15541 atagcctgat acagtttagc agcggacttt tccttaaccc cctctaaaag gaggaaatcc
    15601 tcttcttgca aacgataaat atccgccaca tccttgacta aattagcagc aaaaagcttc
    15661 tcaacaatag atggaccaag gcctgtaata ttcatagcat cacgagaagc aaagtgaatc
    15721 aagccttcca tgatttgagc agggcaacgc ggattgatac aacgtagggc cacttcatct
    15781 tcaaagtgca acaagtcaga gttacaactt ggacagtttg tagggatatc tagtttttct
    15841 tcagaaaccc gtttggactc taccacacgt aaaacggcag ggatgatgtc accagcctta
    15901 tatacaatga ccgtatcgtc ttttcggata tctttttcag caatataatc tacattgtgc
    15961 agggtcgcac ggctaacagt cgtaccggca agttgtactg gtgttagatt agcagttgga
    16021 gttacaacac cggtacggcc aactgtccag tcaactgata agagttgagc ttctttttct
    16081 tcggcaggga acttgtaggc tactgcccac tttggagcct taacggtaaa accaagttct
    16141 tcttgacttg ctaggtcgtt gaccttgatt accactccat caatatcgta aggcagattt
    16201 tcccgttcct gtcctacttc ttggataaaa ttccagattt catctatgtt ttcagccaag
    16261 attcgcttag gattgaccac aaaacctagt tgttctaggt acttcaaacc cttttcttgg
    16321 ctatcacgag ttgaagggct ggcttcttga tagagaaacg ttgcaagatt acgcttggca
    16381 actactgctg tatccaactg acgcagagtt cctgctgccg cattacgagg attagcaaat
    16441 tcaggctctc cattttcttg gcgcacttgg ttaacttggt caaaggaagc gcgtggcatg
    16501 taacattccc cacgaactgt gatatctagt tcttctggca aagtcaaagg gatgtcctta
    16561 acacgcttga ggttttctgt gatattttca ccaattgaac catctccacg tgttacccca
    16621 gcaaccaaaa tccccttttc ataagtcagc gagatagata agccatcgat tttcagctca
    16681 caaatatagg tcggatgagc cacttcctta cgaacacgcg catcaaaagc atctagctcc
    16741 tcacgtgaaa aagcatcctg caaactataa agaggatact gatgactgta tttttcaaaa
    16801 ccatctaaaa ccttgccacc aacacgatga gtcggactgt ctgctagcac ttgctctgga
    16861 taagcagttt ctaactcgac caactcacgg taaaggcggt catactcact gtctgaaacc
    16921 gagggattat cgctggtata gtactcagtc gcatagcgat tgagcaaagc gactaactca
    16981 ttcattcttt tattcataag accattttac cataaaacaa gccctcctca caaacgagaa
    17041 gggcggaaaa aacacttagt ttgaaattat ttttgaaact caagcaacct tatatcaatt
    17101 tttcaaaatg agttcgaaca taaataaacg atatacaaga caagatgata acaccacttc
    17161 caattatcag gaaagaagag agatgtacac ttggcaagac tgtcataaat ccttttgcaa
    17221 taggcataaa tagaatagct aaggtaaaaa ttgtactcag tactcttcca agaaattcgc
    17281 tctcaacctt ggtttgtact tgagtaaaaa agtgaatatt aaaaatcgtc ataaacaatt
    17341 cacaaactaa atttccagaa aaggaaagaa aagttggaag tggtaatccc atcataaaaa
    17401 ctccgacacc tgtcaaagcc agtaaaatca aaagattata aatattagct ttaattttac
    17461 tagctagaag agccccaatg atggaaccaa tagcccccat agttaaaata cttgcatagg
    17521 ctccttctga cccgtaaagc tgattcgaaa agggaagtag aaattcaaaa gctgcaaaaa
    17581 agaaattaac gctggaagct accagcaaaa ggaagaaaat ttcttgctga tgccagatat
    17641 agtgtaaccc atccttgata tctacaaaaa tatctctccc agtaaaagcc tttttctctt
    17701 gaacttttgc ttcctctttt ggaaggaaag ccactagaac aaaagcaatg aaaaaagtca
    17761 gcgagtctag cagtagcgtc atatggagac ttgcaaactg taaaacaagg aaggaaagaa
    17821 caggagagct aacacctaca acctgcaaaa ccagctctag gcgagaatta tagatcacaa
    17881 tctcatcttt ctccaccact tcagttatga tagctttatt ggctgtgcga gaaaaggcaa
    17941 aagcaatagc ctgcacaatg ttagcaacaa tcaaagcgcc aatcatccag ctatcattcc
    18001 ttatgaaaga aatagccaga caaagaatcc cacaaacaag atctgccgtc attaaaatct
    18061 tacgacgaga aaaacggtct gaaataactc cgccaaaggg attgacgaga atagatgtga
    18121 cgagctcaga aatctgatac attcctaaaa ctgtctgtcc tatagtcccc atagaagcca
    18181 accagacact atttccataa tcatagagca tatttcccat tttattgata gccccacggc
    18241 taatcaactg cactgcatag cgattcatat taaagctcct ctcaaatttt gaaactattg
    18301 tatcaaaacc gaaaggagct ttttattttt tcccttattt gggaaaatta acttttgaca
    18361 aatttttcgt agtgttcctg ataataggct acttgctctg gaagacctaa cacatcaaaa
    18421 atatgtatgg cctcttgcat ctgcttacag ccttctttac actgtccttt ttgatataag
    18481 gcaaaacctt ttaaataatg gaaaacatta cgctcataaa gcttaatacc tttgtcaata
    18541 atcttctctg tataagcctc aaaatagttg gcattataaa aagaagaatg ctctaaacaa
    18601 tgctggtaac aattgagggc caaaatcaac actaatctct tatggctact aatctcttgg
    18661 taaaattcct ccctctccat aacttctcta ccaatccgag tgacataatc cacatcgtag
    18721 aaactataga ggttaccgaa aagaatcaac tcatacatgg tccattcttc tgttttgaag
    18781 agataatctg ctaccttatc caaatcatcc tgcttcatat cataactcgc atctctttga
    18841 caaatcagac cctgtagcaa aatccagttc agctcaaaat aaaggggagt cgtcgaactc
    18901 ttagactttt caagttgttc tctttgaagc ttttgaaaac ctgcaatatc gtttgaatag
    18961 taaagtggga taatctgtgc catcatagac acatgttcat gattatgaaa attccttgcc
    19021 ttatccatga aattttcgat tgttacatga atgttatcca aaatctcaaa gaaacgggag
    19081 actgccaggt cagactcccc aagctcaaag cgagataact gagaggtaga gcaggattcg
    19141 cctgctgctt ccttcaaaga ataatttcca cttgttcgaa attcacgaaa tacttttcca
    19201 agatgttcca tctttacacc tgctctgata attcttccca ctcaagcata gcttcttcct
    19261 gacgatggct gattttgtcc agctcagcct gtaattccat gagtttgtcg gcatcgtttg
    19321 tttccaacat ttgttcagaa atggcttggc tttgactttc tagctcttca atttcagctt
    19381 ctagactttc gatttgtcgc atgagtttgc gaacttcttt ttgactttct ttctgggcct
    19441 gatagtcatt gactggactt gcttcctttg cttgattgct agttgaagct tcctcagtct
    19501 gactcatttc tgctgttgct ttcttctcaa catagtagtc gtaatctcca aggtagagag
    19561 ttgaaccatt ctcagacaat tccaaaacat gagttgccac acgattgata aagtaacgat
    19621 catgactgac aaaaagcaag gtaccatcaa agtcaatcaa ggcattttct agcacttcct
    19681 tactatcaat atccaagtga ttggtcggct catccagaat caaaaagtta ttgttttcca
    19741 tagacaattt agctaaaagc aaacgagctt tttcgccacc agatagcatg ccgactgatt
    19801 ttttaacatc atctcctgag aaaaggaagg ctccaagacg gttgcggatt tcaacttctg
    19861 gtgtcaattt gaaatcattc cagagttcat ccagcaccgt attacttggt gtcagcttgc
    19921 tttgggtttg gtcatagtaa ccaacctcaa cattagcgcc aaagcgcttt tctcccttga
    19981 taaacggaat ttgatccacg attgatttga taaaggttga ttttccgata ccattgggac
    20041 caacgatagc aacagcattc atcttacgaa ggtctaggtt aatcggttgt gacaggactt
    20101 ccccatcata gccaacagcc gcattttcaa cagtcaaaac aacattgccc gacgtttttt
    20161 cagactggaa ggtcatgttg gctgctttct tgccagcttc cggcttgtcc aaacgctcca
    20221 ttttttctag ttgtttacgg cgagattgag cacgtttagt cgttgaagca cgaactagat
    20281 tgcgattgac aaagtcttcc agagcagcga tttccttctg ttgcttttca tagttttttg
    20341 cctcagtagc tagcttttgc tccttcaact cgacaaaacg agagtaattc cccacatagc
    20401 gatccaagga atgcttggtc aaatctagcg taattgtcgc aaccttgtcc aagaaataac
    20461 ggtcgtggct gacgataatg agggcaccgc tatagtttac caagtaattc tctagccagg
    20521 agatggtttc aatatccaag tggttagttg gctcgtccaa gaccaagaga ttgggctttt
    20581 caaggagcat tttagctaga gccaaacgag tattttgacc acctgaaagt tcagctattt
    20641 tcatctgcca catagactcg tcaaacttga atccattcaa aatcgctcga atatcagctt
    20701 cataggtaaa gccacctgct tggcgaaaat tctcagataa gcggtcataa tctgacatca
    20761 gtttatccaa atcctcacca gacttttcac ccatctccag ctccatctga cgcagttgtc
    20821 tctccgtccg acgcaaatca ttaaagacat gaagcatttc atcgtagatg gtattttcag
    20881 actcaaaacg gctatcttgg gctaggtaag acagagaaat atcttttttc ttattgattt
    20941 ctccgctagt tggctcctct tctccaacta aaatcttcaa aagagtagac ttacctgcac
    21001 catttttccc aacaagagca atccgatctc gttcatcaac ctgcaggttg atattatcga
    21061 aaagaacctc tcctgcaaaa gaacgttcaa ttttattagc ttgtaaaata atcataagag
    21121 tagtatagca tgtttcccta aggcattcaa gataatcgta agtcttttag tacaactttt
    21181 ataacataaa ataaactaaa ttatgtatat tttatattag attccttcac tatcttgttg
    21241 gattttctaa ccagctaatc ttgtttcaaa tagttatcgc acaagcctat tatttaattc
    21301 ttttcattat ttacgtacgc gtatagc
//
LOCUS       DAVHLA010000036        21320 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVHLA010000036 DAVHLA010000000
VERSION     DAVHLA010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21320
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.036"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            62..358
                     /locus_tag="VVO77_001561"
     CDS             62..358
                     /locus_tag="VVO77_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEU5693551.1"
                     /translation="MDTPDENGYVADNYRITYLEAHIKAMRDAIYQDGVDLLGYTTWG
                     CIDLVSAGTGEMNKRYGFIYVDRDNVGNGALKRSKKKSFYWYKDVIDSNGASIG"
     gene            479..1423
                     /gene="manA"
                     /locus_tag="VVO77_001562"
     CDS             479..1423
                     /gene="manA"
                     /locus_tag="VVO77_001562"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEU5693552.1"
                     /translation="MSEPLFLQSVMQEKIWGGAKLRDEFGYDIPSEKIGEYWAISAHP
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTLLVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVESWTLEGQDLELIVSHP"
     gene            complement(1444..2807)
                     /locus_tag="VVO77_001563"
                     /pseudo
     CDS             complement(1444..2807)
                     /locus_tag="VVO77_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821651.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            3035..3784
                     /locus_tag="VVO77_001564"
     CDS             3035..3784
                     /locus_tag="VVO77_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEU5693553.1"
                     /translation="MYHIKEAAQLSGVSVKTLHHYDKIGLLVPLKSENGYRTYSQEDL
                     ERLQVILYYKYLGFSLEKIAELLKEERTDLLPHLTRQLDYLTRERQHLDTLISTLQKT
                     IQEQKGERKMTIEEKFTGFSYQDNQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAF
                     NQVFQTLAQNLQVGLPATATENQEQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEF
                     KENIDKFGSGTAQYTSDAIAAYVQTNAEKIG"
     gene            complement(3804..4259)
                     /locus_tag="VVO77_001565"
     CDS             complement(3804..4259)
                     /locus_tag="VVO77_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU5693554.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWPGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(4279..5454)
                     /locus_tag="VVO77_001566"
     CDS             complement(4279..5454)
                     /locus_tag="VVO77_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEU5693555.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDNQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(5513..6358)
                     /locus_tag="VVO77_001567"
     CDS             complement(5513..6358)
                     /locus_tag="VVO77_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU5693556.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            6483..7040
                     /locus_tag="VVO77_001568"
     CDS             6483..7040
                     /locus_tag="VVO77_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEU5693557.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            7059..7526
                     /locus_tag="VVO77_001569"
     CDS             7059..7526
                     /locus_tag="VVO77_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEU5693558.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            7615..8244
                     /gene="upp"
                     /locus_tag="VVO77_001570"
     CDS             7615..8244
                     /gene="upp"
                     /locus_tag="VVO77_001570"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEU5693559.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            8418..9008
                     /gene="clpP"
                     /locus_tag="VVO77_001571"
     CDS             8418..9008
                     /gene="clpP"
                     /locus_tag="VVO77_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEU5693560.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            9087..9335
                     /locus_tag="VVO77_001572"
     CDS             9087..9335
                     /locus_tag="VVO77_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEU5693561.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            9437..10597
                     /locus_tag="VVO77_001573"
     CDS             9437..10597
                     /locus_tag="VVO77_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU5693562.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDSLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            10865..11734
                     /locus_tag="VVO77_001574"
     CDS             10865..11734
                     /locus_tag="VVO77_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEU5693563.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            11738..12694
                     /locus_tag="VVO77_001575"
     CDS             11738..12694
                     /locus_tag="VVO77_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEU5693564.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            12694..13458
                     /locus_tag="VVO77_001576"
     CDS             12694..13458
                     /locus_tag="VVO77_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5693565.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            13458..14168
                     /locus_tag="VVO77_001577"
     CDS             13458..14168
                     /locus_tag="VVO77_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5693566.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            14476..15132
                     /locus_tag="VVO77_001578"
     CDS             14476..15132
                     /locus_tag="VVO77_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU5693567.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIISL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            15240..16335
                     /gene="prfB"
                     /locus_tag="VVO77_001579"
     CDS             join(15240..15311,15313..16335)
                     /gene="prfB"
                     /locus_tag="VVO77_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEU5693568.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQEKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSYEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            16353..17045
                     /gene="ftsE"
                     /locus_tag="VVO77_001580"
     CDS             16353..17045
                     /gene="ftsE"
                     /locus_tag="VVO77_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEU5693569.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            17038..17964
                     /locus_tag="VVO77_001581"
     CDS             17038..17964
                     /locus_tag="VVO77_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5693570.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            18250..20430
                     /locus_tag="VVO77_001582"
     CDS             18250..20430
                     /locus_tag="VVO77_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU5693571.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFAPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEV
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     NAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            20482..21297
                     /locus_tag="VVO77_001583"
     CDS             20482..21297
                     /locus_tag="VVO77_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEU5693572.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLSEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAMLNWK"
BASE COUNT         6530 a         4016 c         4645 g         6129 t
ORIGIN      
        1 actattatat aatgcttttt gattttagtt tagtattatc gtagaaaatg gactcggtgc
       61 tatggataca ccggatgaga atggttatgt agcagataac tatcggatta cttacttaga
      121 ggcccacatc aaggccatgc gagatgccat ttaccaagac ggggttgact tgcttggtta
      181 tacgacttgg ggctgtatcg atctggtttc agctggcaca ggggaaatga ataagcgcta
      241 tggctttatc tatgtagatc gagataatgt aggaaacgga gctctcaaac gtagcaagaa
      301 gaagtccttc tattggtaca aggatgtcat tgatagcaat ggtgcaagca tcgggtagag
      361 cacatttgtt tactattttt ataaaatctt ctccctgctt tataagatgt aaaaaagagt
      421 tcaattcgaa ctcttttttt gctataatga ggggagaaaa atcagacagg agatcgacat
      481 gtcagaacca ttatttttac aatcagttat gcaagaaaaa atctggggtg gagccaagct
      541 acgtgatgag tttggctacg acatcccaag tgaaaaaatc ggagaatatt gggccatctc
      601 agcccatcca aatggagtct ctaaagttgc caatggtcgt tacgagggaa cagatcttgc
      661 tactttgtat gcggaacacc gtgaattatt tggcaatcgt ccagaacctg tatttccact
      721 tttgaccaag atcctcgatg ccaacgactg gctcagtgtc caagttcacc cagacgatgc
      781 ttatggactc gagcatgaag gcgaactcgg aaaaacagaa tgctggtaca ttatcgcagc
      841 ggatgaaggt tcagagatta tctacggtca caatgccaag tcaaaagaag aactccgcca
      901 gcaaatcgag gataagaact gggatgcgct gttgacaaaa gtgccagtta aagcaggaga
      961 tttcttctat gtaccaagcg gtaccatgca cgctatcggg gcgggtatct tgattcttga
     1021 aacccagcag tctagcgata ccacttaccg tgtctatgac tttgaccgaa aggacgataa
     1081 gggcaacttg cgtgaacttc accttgaaaa atctatcgat gtcttgaaca ttggtgaacc
     1141 cgcaaatagc cgtccagtga caatcaaagc agatgatcta cgttccactc tccttgtatc
     1201 caatgatttc ttcgcagttt acaaatggga aattactgga aaagttaact ttgaaaagac
     1261 agctgactac agcttgttga gtgtcttggc tggtcaaggt caactaactg ttgacgggaa
     1321 aaactatcca atccaaaaag ggagacactt tatcctacca agtgatgttg aatcttggac
     1381 tttagaaggg caagatttgg aattgattgt tagtcatcca taaaaagaaa gggcctgagt
     1441 tcactactca agtccttttt gattacataa attgggcgat gaagaccacg atgatgattg
     1501 gaatgacgaa acgaagaaac gaaggaggaa gagccagact tggaaaagta cttgtttcca
     1561 ggctctttca tcgagatgga gttcctccat aacaagagcc tttttaaaga tatagcctgt
     1621 aaaaagtgaa aggcagagag ctccaaatgg catgagaaga ttggaaacca agaaatccat
     1681 ggcatcaaag aaagtcttac caaagatgtg aacatccgcc ataactccat aggatagggc
     1741 tgaaggaatg ccaaagacaa aggtcaaaat tcctaaaata acactccatt tggcacgttt
     1801 gctgttatcc tggttggtga tattgcccac attgatctcc agcatcacga cagaaaaagt
     1861 gactggcgca aaaaggaaga gcaagaggaa aaggacgtag aaaatggttc caaaaggcat
     1921 cttgtcaaag agttgaggca agacgataaa gagcaagctc ggtccccctt cagactggat
     1981 attgaagggg gaccgagctt ggaaaatggc tagacctgcc atgatggata tcgagatatt
     2041 catggctacg atggagattc ctgactggac taggttggtt ttcttgtcca agtaagaagc
     2101 ataggtcaac atgactgtaa cccctagtga gagggcaaag aaagattgtc ccagagcata
     2161 gaggagacca gcgctagtca gttttgaaaa gtctggtttg aggaagtaaa gaaccccttc
     2221 catggcattt ggcaaactga gagagcgacc gatgataaca acaaagatga taaagagcag
     2281 gggcatcatg actttcgaag ctctttcaat ccctttttga accccacgtg atacaataaa
     2341 gatatttaat aagataaagg ctgcttgagc tcctagggca atggctggat ttgaaatgat
     2401 tgaagtaaat aactgagcat aatcacccgt tccaccaagt tggaacaatt tcccaaactc
     2461 aatacctaga tagactagaa tccatcctcc gataacactg taaaaagata agaggataaa
     2521 gagggcaaag gcgccaatcc aaccgataaa gttgtacttg ttattcttgc ccagttttcc
     2581 aaaggttttg atagcggaaa cgccagcact acggccaagg gcaaactcag ccagcaggag
     2641 agggaaaccg attaaaatag tggaaatgag aaagattagt aaaaagcctc catcgccatt
     2701 agcagcagtc atgtagggaa acttccaaac ggaaccaagc ccgatggcca gccagcagat
     2761 gctagaataa aaccaagttt cgacccccat tgtgattttt ctgacatagt taaactctga
     2821 tctccttttt caaaataaga aaaagctact tgagttgtca aatagccttc tgtttgattg
     2881 atagacttga ctatcctatc atgttttcta aggtctgtca agaaaatcat tttcaagttt
     2941 tcacaccttt ctcaaaaaag ttaaaaaatt ttctcaaaaa cgcttgactc tgacctaagg
     3001 ggaggggtta tactatcatt gtaaggagga aatcatgtac catataaaag aagctgcgca
     3061 gctttcaggt gtctctgtca agaccctgca tcactatgac aagataggac tcttggtccc
     3121 cttaaagtcg gaaaacggct atcgaaccta cagtcaagag gatttggaac gccttcaggt
     3181 cattctttac tacaaatatc taggcttttc tttagagaaa atagcagagc tgttaaagga
     3241 agaaaggaca gatttattgc cccatttgac taggcagttg gactatctaa ctcgcgaaag
     3301 gcaacatctg gataccttga tttccacctt gcaaaaaact attcaagaac aaaaaggaga
     3361 aagaaaaatg accattgagg aaaaattcac gggatttagc tatcaagaca atcaaaaata
     3421 ccaccaagaa gcggtagaga aatatggtca agaagtcatg ggacaagcgc tcgaacgcca
     3481 aaaaggtcac gaagacgagg ctacggccgc ctttaaccaa gtctttcaaa ctttggcaca
     3541 aaatcttcaa gttggtttac ctgcaacagc aaccgaaaac caagagcaag cagccaagct
     3601 cttgcaagcc attcgcactt atggatttga ctgctctatt gaggtattcg gtcatatcgg
     3661 taaaggttac gtctataacc cagagtttaa ggaaaacatt gacaagtttg gttctggaac
     3721 agcccagtac acgtcagatg ccattgcagc ttacgttcag acaaatgcag aaaaaatagg
     3781 ctaggaattt cctagcctat tttttacttc aaatcataaa gccagtcgtc accgtttttg
     3841 tagtaaaaga attcactgag atcttcttct agaaacacac gaagcatatc agacatatca
     3901 tcggttgcaa gttttagatg agaaagattt tcaaagtcct cccaccaaac tttcccttcg
     3961 tctgaagact ggagttcacc agtaaagtgt tctgtcttgt aaaaaaggac gacataacga
     4021 taatccttgt cgtcatacca gtttttgata ccacagagtt ggggtttgga aatgatcaga
     4081 ccagtttctt ctttcacttc acgaatgaca gcatcgacaa aggattcgcc acgttcaaca
     4141 tgaccaccag gaaaagtaat gccaggccag tcgggactaa ctcggtcttg gaccaggacc
     4201 ttatctccgt ttttaatcat acacatgtta acaaattcga ctgcctctct tctgttcatt
     4261 cttcacaacc tttaatcttt aatcataatg cagacttccc gccacccagc cggtacagag
     4321 ggcagaagtg atgttaaagc cacccgtgtg ggcattgata tccataactt cgcctgcaaa
     4381 gtggaggcca ggtaccagct tactttcaag ggttttagga ttgatttcct tgagactgac
     4441 tccacccttg gtaacaaagg actttgcaag ggacattttt ccagttacag gaattttaag
     4501 ttctttaatg gactggacaa gctgttctcg ttccttttca gtcagctgtt tgactttttc
     4561 aggatatcct tgtacaaaaa attcggccaa gcgttctggt aacaaggttt ttaaagcgtt
     4621 tttcaaggat ttttcccgat tttcttctag aaatgtaacc aagtccttct cagaaagttg
     4681 aggcaaaaca tcgagtgaga gaacctcccc acctttgaca aagctagaca tgcgtagggc
     4741 agcaggacct gacaaaccaa agtgggtaaa gagtaaatca tgagtgatga catgcttacc
     4801 ataacttagg gtcacatcgt ccaaagaaat cccttgtaag gctttatgtg gaaaatctgt
     4861 taataaagga ctttcagcag cctcaagatc ggtgatggta tgcttaaaat ggcgagcaat
     4921 ctcgtgacca aaaccagtcg aaccagtcga aggataagac ttaccacctg ttgtgacaat
     4981 gagtttctca caagtgaagg tttgatccgc tgacttaagg acaaactggt tatctacttt
     5041 tttaacagaa acgatttcta tttgagtagc aacttgacca cctagttcgg tgattttctt
     5101 ttccaaagct tcgataatag tccgagactt gtcactggct ggaaagacgc gtccgtggtc
     5161 ttcgacctta agtttaacac cattttctgt aaaaaagttg atgatgtcat gattatcgaa
     5221 ctgggagaaa acactgtaaa gaaagcgtcc gtttccagga attccagcta gcaggttgtc
     5281 taagctacca ttgttggtca cattgcaacg tcccccacca gtcccagcta atttttttcc
     5341 aagtttccga tttttttcga tgaggagggt tttctgtcca taaaagctac tggaaatcgt
     5401 agccatcata ccagcaggtc ccccaccgat gacaatagta tcaaaatgtt tcatagctct
     5461 attgtaccac aaaaaaacaa gagatgatgg tcacctcttg tcaagaatgc aattaatcaa
     5521 tttcatagcc catcagcaaa ccgccctctt ctgcatagaa actgcagaga ccagaggttg
     5581 gtagaatttt aatatccgct tgtgggaagg tttcacggat tcgctctgag agctgttgac
     5641 aacatttttc gttattgcgt tgggccatga caatacggcc accagcatat ccagctttta
     5701 ctaactcatc ataggcagct tgaactgatt tctttgatcc ccttgctttt tgtagcaatt
     5761 cgagagtccc agtttcacta gcttttccga ccatacgaat gttgagaagg ccaacgaccg
     5821 taccgataag cttgctcaaa cggccgttct tcaccaagtt atcgactttg gctaggacaa
     5881 agagcaactt agttttttct tgataggcgg tgatagcttc aaccacttct tcaaaagaca
     5941 agccctggtc aatcaagtca ttcaattttt ctacgagtag gtcaacttca ccaccagcag
     6001 ataaactatc aatcacatga atcttagtgt caggatggtc ttccagataa atattctttg
     6061 ctagttgagc actattgtga ctgccagaaa gggtacctgt gatggttact aggaaaatgt
     6121 ttttggcacc ttcaaatgct cgcaaatagt catctgggct tggacaagct gattttgaag
     6181 cttctgcagt tgcatacatg gtttccatca tttggtcaat atcgagactg gcgtcatcaa
     6241 caaagacctg atcagctact tgaatggtta aggggacact tacaaaggtt gtgttaatag
     6301 ctggtgttgg cagttgacga taatcacaac cagagtcagc aataatcttc caagtcatag
     6361 aaattctcca tctttgtcag ttatacattg acaaaggttc tgtctttttt tacaattata
     6421 tcatgaaaac tcttgaaaca aaagcatcat ccgtctgttg tgacaagtag aaagaaaatg
     6481 ttatgtctga acgtagaatc tctgaaaagt ctcttgaaaa tctcagaaaa tcaaatcaag
     6541 aatccaattt attaaccaga gaagccattg aaacagccct cttgcaactc ttggaaaaaa
     6601 aggagctgac caagattagt atttctgaat tggtcaaacg tgcaggtgtt tcgcgtgcgg
     6661 ccttttatcg caattatgac tccaaagagg aaattttaga gagcgtcttt aaacgaactg
     6721 tccacaatat tatggaacag ctgcatcatt acgatttaaa gacagacctt tatttggttt
     6781 gggttcacct tttccgggag gccagaaagg aagctagagt aattcaattg gccttggatt
     6841 accatctgga aaaaatcttt gtccaagcca tgcaggaatt tctagaaaaa taccatggga
     6901 aatcaaaagg tgtcagctct tatcttcatt ccttctggag ctcagccatc gtctctgtcc
     6961 ttctaaaatg gatcaaggat ggcatgaagg taccagctga aaagattgca gatttaggtt
     7021 taccattttt taaaaaatag agaaaaagga gaaaagagat gactgaaaaa agactggcct
     7081 gggatgagta ttttgcagcc caagccctac taattgcgaa tcgttccact tgtaaacgtg
     7141 ctaaagtggg cgcgattctg gtaaaagata ataaggttat ttccactggt tacaatggtt
     7201 cggtgtcagg gactgagcat tgtattgatc acgaatgttt ggtcattgaa ggccactgtg
     7261 ttcgcaccct tcacgctgag gtcaatgcta tccttcaagg tgctgagcgt ggtgttccca
     7321 aaggctttac agcctatgta acccattttc cttgtctcaa ctgtacaaaa caattgcttc
     7381 aggtcggctg caagcgcgtg gtttatatca accagtaccg aatggacgac tacgcccaat
     7441 acctttatca agaaaaaggg acagaattga cccatttacc acttgagaca gtacagacag
     7501 ctcttaaaga ggctgatcta atgtaaaaat tatcaaaaat aaatggttta gaaagatttt
     7561 taaaccgttt tttggtataa tgagaagaat aaattgaaag aaggaattcc aaaaatggga
     7621 aaaattgaag ttattaatca cccactgatt caacacaaat tgtcaatctt gcgtcgtaca
     7681 gatacttcta caaaagcttt tcgtgagcta gtagatgaga ttgcaatgtt gatggggtat
     7741 gaagtacttc gtgatcttcc actagaagat gtggaaatcg aaacaccaat tacaaaaaca
     7801 gttcaaaaac aattggcagg taagaaattg gccatcgtcc caatcttgcg tgcaggtatc
     7861 gggatggttg atggtctctt gagcttggtt ccagctgcta aagttggcca catcggtatg
     7921 taccgtgatg aagaaacact tcaaccagtt gaatacttgg tgaaattgcc tgaggacatt
     7981 gaccaacgtc aaatttttgt agtagaccca atgttggcaa caggtggctc agcaatcttg
     8041 gctgttgatt ctcttaaaaa acgtggcgca tcaaatatca aatttgtctg ccttgtatct
     8101 gctccagagg gtgtaaaagc ccttcaagaa gctcatccag atgtagaaat ctttacagca
     8161 gccttggatg aacgtttgaa cgaacacggt tatatcgttc caggtcttgg agatgctgga
     8221 gaccgcttgt tcggtacaaa ataagatcga aaagaagaat gacttggaaa agtatttcca
     8281 gtcacgaaag gaggttgggt ttttgtttct gtctaatgaa agcagagcaa aaatttgacc
     8341 ttttttgacc aagatattat aatagtctta tcttcagtca tttgaccaac aaaattaaaa
     8401 ctcaaaagga gaaatgaatg attcctgtag ttattgaaca aacaagccgt ggagaacgtt
     8461 cttacgatat ttactcacgt cttctcaaag accgcatcat tatgctgaca ggtccggttg
     8521 aagacaatat ggctaactct gttattgccc aattgctttt cttggatgcc caagatagta
     8581 caaaagatat ttacctttat gtcaatacac caggtggttc tgtttcagct ggtttggcaa
     8641 tcgtagatac catgaacttt atcaaggcag atgtccaaac cattgttatg ggaatggctg
     8701 catctatggg aacagtcatc gcatcaagtg gagcaaaagg caaacgtttc atgcttccaa
     8761 atgctgaata catgattcat caaccaatgg gcggtacagg tggtggtacc caacaaactg
     8821 atatggctat cgctgcagaa cacttgctca aaactcgtaa taccttggaa aaaatcttgg
     8881 ctgaaaattc aggtcagtca atggaaaaag tccatgcaga tgcagaacgt gataactgga
     8941 tgagcgccca ggaaacactt gaatatggct ttattgatga aattatggcc aacaattcat
     9001 tgaactaatg atgatagaag gcaaactcga ctgggtttgc tttttttggt ataataggga
     9061 gagatttctt agaaagagga tttatcatgt ttgaaaaagt caatcgctct ggcttgatta
     9121 tctatcttta ctataatcgt gatgccaaaa aactgcagga ttatggagat attacctatc
     9181 attccaagaa acatcgttac ttacaactct atgttccaac tcaagaagtg gagcaattgg
     9241 tcggacgctt gagcaaggaa aaatttatta aaaaagttag agtttgtcat atccaagagt
     9301 tggaaacacc ctttgtgggc aatctttatc gataggaaaa cgttatcatc gaaaaagttc
     9361 aaggaaaaca ttgacaattt tctgataatt cggtatattc ttaacagact atttaagaaa
     9421 taaggagaca aaaaagatga agaaaaaatt tgccctatcg tttgtggcgc ttgcaagtgt
     9481 agcacttctt gcagcctgtg gagaagtgaa gtctggagca gtcaacactg ctggtaactc
     9541 agtagaggaa aagacaatta aaatcgggtt taactttgaa gaatcaggtt ctttagctgc
     9601 atacggaaca gctgaacaaa aaggtgccca attggctgtt gatgaaatca atgccgcagg
     9661 tggtatcgat ggaaaacaaa tcgaagtagt cgataaagat aataagtctg aaacagctga
     9721 ggctgcttca gttacaacta accttgtaac ccaatctaaa gtatcagcag tcgtaggacc
     9781 tgcgacatct ggtgcgactg cagctgcggt agcgaacgct acaaaagcag gtgttccctt
     9841 gatctcacca agtgcgactc aagatggatt gactaaaggt caagattacc tctttattgg
     9901 aactttccaa gatagcttcc aaggaaaaat tatctcaaac tatgtttctg aaaaattaaa
     9961 tgctaagaaa gttgttcttt acactgacaa tgccagtgac tatgctaaag ggattgccaa
    10021 atctttccgc gagtcataca agggtgaaat cgttgcagat gaaactttcg tagcaggtga
    10081 cacagacttc caagcagccc ttacaaaaat gaaagggaaa gactttgatg ctatcgttgt
    10141 tcctggttac tataatgagg ctggtaagat tgtaaaccaa gcgcgtggca tgggaattga
    10201 caaaccaatc gttggtggtg atggattcaa cggtgaggag tttgtacaac aagcaactgc
    10261 tgaaaaagca tcaaacatct actttatctc aggcttctca actactgtag aagtttcagc
    10321 taaagctaaa gccttccttg acgcttaccg tgctaagtac aatgaagagc cttcaacatt
    10381 tgcagccttg gcttatgatt cagttcacct tgtagcaaac gcagcaaaag gtgctaaaaa
    10441 ttcaggtgaa atcaaggata gccttgctaa aacaaaagat tttgaaggtg taactggtca
    10501 aacaagcttc gatgcagacc acaacacagt caaaactgct tacatgatga ccatgaacaa
    10561 tggtaaagtt gaagcagcag aagttgtaaa accataatag aaaaatgttg aaatagggaa
    10621 tgagcctttg actcactccc tgtttcgata tttaatactc ttcgaaaatc tcttcaaact
    10681 gcgtcaacgt cgccttggat tatatatgtg actgacttcg tcagtcttat ctacaacctc
    10741 aaagcagtgc tttgagcaac ctgcggctag tttcctagtt tgctctttga ttttcattga
    10801 gtataagaac ctatcaaaaa gtgagggaaa accctcggaa ttataaatag aaagagtgaa
    10861 tcttatgctc caacaactcg taaatggttt gattctaggt agtgtttacg cgctgttagc
    10921 cctaggatat accatggttt acggaattat caagctcatc aacttcgccc atggtgatat
    10981 ttatatgatg ggagccttta tcggttattt cttgatcaat tctttccaaa tgaatttctt
    11041 tgtagcgctt attgtagcta tgctagcgac agctattctt ggtgtcgtga ttgagtttct
    11101 tgcttaccga cctttgcgcc actctactcg tattgctgtt ttgattacgg ctattggggt
    11161 ttctttccta ttggagtatg gaatggtcta tctggttggt gccaataccc gtgccttccc
    11221 tcaagcgatt caaacagttc gatatgattt gggaccaatt agcttaacaa atgtgcagtt
    11281 aatgattttg gccatttcct tgattttgat gattttgtta caagtcattg tccaaaagac
    11341 taagatgggg aaagccatgc gtgcagtatc agtagatagc gacgcggcgc aattgatggg
    11401 gatcaatgta aaccgtacga ttagctttac cttcgctttg ggttctgctc ttgcgggtgc
    11461 ggctggtgtt ctgattgctc tttattataa ctctcttgag cctttgatgg gggttactcc
    11521 aggtcttaaa tctttcgttg ccgcagtact tggtggtatc ggaattattc ctggtgcggc
    11581 tcttggtggc tttgtgattg gtctattgga aacctttgcg acagcctttg ggatgtcaga
    11641 tttccgtgat gccattgttt atggaatctt gttgttgatc ttgattgtcc gcccagctgg
    11701 tatccttggt aagaatgtga aagagaaggt gtaaacgatg aaggaaaatt taaaagttaa
    11761 tattctatgg ttactccttt tgttagctgg ctatagcttg attagtgtac tggtttcagt
    11821 cggagtactt aatctattct atgtacagat tttacaacaa attggaatta atattatttt
    11881 ggctgttggt ctcaacttaa tcgttggttt ttcaggacaa ttttcacttg gtcatgctgg
    11941 tttcatggcg attggtgcct atgcagcagc tattattggt tctaaatcac caacctacgg
    12001 tgccttcttt ggagctatgc ttgtaggggc tttgctttca ggagcagttg ccttacttgt
    12061 cggcattcca accttgcgct tgaaggggga ctatcttgcg gtagcaactc tgggtgtttc
    12121 tgaaattatc cgtatcttta tcatcaatgg tggaagtctt acaaatggtg cggcaggtat
    12181 cttagggatt cctaacttta caacttggca aatggtttac ttctttgtcg tgattacaac
    12241 cattgcaacc ttgaacttct tgcgtagccc aattggccgt tcaaccctct ctgttcgtga
    12301 agatgaaatc gctgctgagt cagttggggt taatacgact aaaattaaaa tcatcgcttt
    12361 tgtctttggt gccattactg caagtattgc tgggtcactt caggcaggat ttatcgggtc
    12421 tgttgtaccg aaagattaca ccttcatcaa ctcaatcaac gttttgatta ttgttgtatt
    12481 tggtggactc ggttccatta caggtgcgat tgtttcggct attgttctgg gaattttgaa
    12541 tatgcttctc caagatgttg ctagtgtgcg tatgattatt tacgctttgg ccttggtatt
    12601 ggtaatgatt ttcagaccag gtggactcct tggaacgtgg gaactgagcc tatcacgttt
    12661 ctttaaaaaa tctaagaagg aggaacaaaa ctaatggcat tacttgaagt aaaacagtta
    12721 accaaacatt ttggtggtct aacagctgtt ggagatgtga ctcttgaatt gaacgaaggg
    12781 gaactggttg gattaatcgg tccaaacgga gctgggaaaa ccaccctttt caaccttttg
    12841 accggtgttt atgaaccaag cgagggaaca gtaaccctag atggtcacct tttgaatggg
    12901 aaatcacctt ataagattgc ctctttggga cttggacgta ctttccaaaa tatccgtctt
    12961 tttaaagatt taacagtttt agacaatgtt ttgattgctt ttggaaacca tcacaaacag
    13021 catgttttta ctagtttctt acgcttacca gctttttaca agagtgaaaa agaattaaag
    13081 gctaaagctt tggaattgtt gaaaatcttt gatttagatg gtgatgcaga gactcttgct
    13141 aaaaatcttt cctacggaca acaacgtcgt ttggaaattg ttcgtgccct tgctacggaa
    13201 cctaaaattc tcttcttaga tgaaccagca gcaggtatga acccacagga aacagccgaa
    13261 ttgactgagt taattcgtcg tatcaaagat gaatttaaga ttacaatcat gttgattgaa
    13321 cacgatatga atctggtcat ggaagtaaca gaacgtatct acgtacttga atatggccgt
    13381 ttaattgctc aaggaactcc agacgaaatt aagaccaata aacgcgttat cgaagcttat
    13441 ctaggaggtg aagcctaatg tctatgttaa aagttgaaaa tctttctgtg cattacggta
    13501 tgatccaagc agtccgtgat gtaagctttg aagttaatga aggagaagtt gtttccctta
    13561 tcggtgccaa cggtgcaggt aagacaacta ttcttcgcac cttgtcaggt ttggttcgac
    13621 caagttcagg aaagattgaa tttttaggtc aagaaatcca aaaaatgcca gctcagaaaa
    13681 tcgtggcagg tggtctttca caagttccag aaggacgcca cgtctttcct ggcttgactg
    13741 ttatggaaaa tcttgaaatg ggagctttct taaagaaaaa tcgtgaagaa aatcaagcta
    13801 acttgaagaa ggttttctca cgctttcctc gtcttgaaga acggaagaac caagatgcag
    13861 ctactctttc aggaggggaa caacaaatgc ttgccatggg acgcgctctt atgtcaacac
    13921 caaaacttct tcttttagat gaaccatcaa tgggacttgc cccaatcttc atccaagaga
    13981 tttttgatat cattcaagat attcagaagc aaggaacaac cgtcctcttg attgaacaaa
    14041 atgccaataa agcactcgca atctctgacc gaggatatgt attggaaaca ggaaaaatcg
    14101 tcctatcagg gacaggaaaa gaactcgctt catcagaaga agtcagaaaa gcatatctag
    14161 gtggctaaaa caatccagtg gattgtttta gtcggcagat gaagattacg aagtaatcat
    14221 caatatagtc cgggggacct ttttagccgg tagattgaga ttgcaaacaa atctgcatct
    14281 acattgaaag cttaatttct aataattgaa aaaatcgaat gaaaagtttc ttaccttcat
    14341 tcacagagct cgattttaga gctctttttg ctagcttatt catacttttc taaattttga
    14401 aaaagaaatg taagcgtttg atagatttgc aaaaagattg tataataggg ataagaatag
    14461 aaaaggagaa gtctcatggc agttaaagat tttatgaccc gcaaggtagt ttatattagt
    14521 ccagatacaa cagtatctca tgcagcagat ttgatgagag agcaaggatt gcaccgcttg
    14581 cctgttatcg aaaatgatca attggttggt ttggtgactg agggaaccat tgcacaagca
    14641 agtccatcta aagcaacaag tctttctatc tatgagatga attatcttct gaataagaca
    14701 aaagtaaaag atgtcatgat tcgcgatgtt gtcactgtct caggctatgc tagtctagaa
    14761 gatgcaactt atctgatgtt gaaaaataag attggtattc tccctgtcgt agataaccat
    14821 caagtatacg gagttattac tgaccgtgac gttttccaag cctttcttga aattgcaggt
    14881 tatggcgaag aagggattcg tgtacgcttt gttacagaag atgaagttgg tgttcttgga
    14941 aaaattattt ctttgattgt agaagaaaat ttgaatatct cccatacagt caatattccg
    15001 cgtaaggatg gtaaggtcat tatcgaagtg caaatcgatg gatcaattga tttaccagcc
    15061 ttgaaagaaa aatttgaagc aaatggtatt caagtggaag aaatcgctcg cacttcagca
    15121 aaagtcttgt aagaagggaa gcccaaaggc ttcttttttc atgaaaaggg gattagagca
    15181 aaagatggaa agaaatgata aaatatgcta taatgaaatg atgtaaaaaa ggagtattta
    15241 tggacatttc agtaattcgt cagaaaattg acgcaaatcg tgaaaaatta gcttctttca
    15301 gggggtctct ttgacctcga agggctagag gaagagattg ccatcttgga aaacaagatg
    15361 acagaacctg atttttggaa cgataatatt gcggcccaaa aaacgtcgca agaattgaat
    15421 gaattaaaaa acacttacaa taccttccat aagatggaag agttgcagga tgaagtcgaa
    15481 attttattgg attttttggc tgaagacgag tcagtgcatg atgaactggt agcgcagtta
    15541 gccgaacttg ataagataat gaccagctac gagatgactc tactcttgtc agaaccttat
    15601 gaccacaaca atgccatctt ggaaatccat ccaggttctg gtggtactga ggcgcaggac
    15661 tggggtgata tgttgcttcg tatgtatact cgttatggta atgctaaagg ctttaaagtg
    15721 gaagtgttgg attaccaagc aggtgatgag gctggtatta agtcggtaac tttatcattt
    15781 gaagggccta atgcctatgg tctcctcaag tcagaaatgg gtgttcatcg cttagtgcga
    15841 atctcaccat ttgactctgc caaacgtcgc catacctctt tcacatctgt agaagtgatg
    15901 ccagaattgg atgatactat tgaagtggaa atccgtgaag atgatatcaa gatggatacc
    15961 ttccgttcag gtggtgccgg tggacaaaac gtcaataagg tttcaacagg tgtacgttta
    16021 acccacattc caactggaat tgttgtccaa tcaacagtgg atcgtaccca gtatggaaat
    16081 agagatcgcg ccatgaagat gttgcaggct aagctctatc aaatggagca agagaagaag
    16141 gctgcggagg tagattctct caaaggtgag aaaaaggaga tcacttgggg aagtcaaatc
    16201 cgttcttatg tcttcacgcc ttatactatg gtaaaagatc accgaactag ctatgaggtt
    16261 gctcaggtag ataaggttat ggatggggac ctagatggtt ttatcgatgc ttatctcaag
    16321 tggcgaatta gctaagatag aaaggaactc acatgtcaat tattgaaatg agagatgtcg
    16381 ttaaaaaata cgacaacgga acgactgctc tacgcggtgt ttcggttagc gttcaaccgg
    16441 gggaatttgc ttacatcgta ggaccttcag gagcagggaa gtcaactttt attcgttctc
    16501 tgtatcgtga agtaaaaatc gataaaggaa gtctatcagt tgctggtttt aatctggtta
    16561 agatcaaaaa gaaagatgtc ccgcttctac gtcgtagtgt tggggttgtc ttccaagatt
    16621 ataaactgtt accaaagaaa actgtctatg aaaatattgc ttacgctatg gaagtaatcg
    16681 gggaaaatcg ccgtaatatc aaaagacgag tgatggaagt tttggacttg gttggattga
    16741 agcataaggt tcgttctttc ccaaatgaac tctcaggtgg ggagcaacag cggattgcga
    16801 ttgcgcgtgc aattgtaaat aatcccaaag tattgatagc tgatgagcca acaggaaatc
    16861 tggatccgga taattcatgg gaaattatga atctcttgga acggattaac ctacaaggaa
    16921 caactatttt gatggcgact cataatagcc agattgtaaa taccttgcgc caccgtgtca
    16981 ttgccattga aaatggccgt gtcgttcgtg acgaatcaaa aggagagtat ggatacgatg
    17041 attagtagat tttttcgcca tttatttgaa gccttaaaaa gtttgaaacg aaatggttgg
    17101 atgacagtag ctgctgtcag ttcagtcatg attactttga ccttggtggc aatatttgca
    17161 tctgttattt tcaatacagc gaaactagct acagatattg aaaataatgt ccgtgtagta
    17221 gtttatatcc gaaaggatgt ggaagataat agtcagacaa ttgaaaaaga aggtcaaact
    17281 gttacaaata atgactacca caaggtatat gattctttga agaacatgtc tacggttaaa
    17341 agtgttacct tttcaagtaa agaagaacaa tatgaaaaat taaccgagat aatgggagat
    17401 aactggaaaa tctttgaagg agatgccaat cctctctatg atgcctatat tgtagaggca
    17461 aacactccaa atgatgtaaa aactatagcc gaagatgcta aaaaaattga aggtgtctct
    17521 gaggttcaag atggcggtgc caatacagaa agactcttca agttagcttc atttatccgt
    17581 gtttggggac tagggattgc tgctttgtta atttttatcg cagttttctt gatttcaaat
    17641 accattcgta ttaccattat ttcccgcagt cgcgaaattc aaatcatgcg cttggtcgga
    17701 gctaaaaaca gttatatccg tggaccgttc ttgttagaag gagcctttat cggtttattg
    17761 ggagctatcg caccatctgt tttggtcttt attgtttatc aaattgttta ccaatctgtc
    17821 aacaaatcgt tggtagggca aaatctatcc atgattagtc cagatttatt tagtccgttg
    17881 atgattgccc tactatttgt gattggggtt ttcattggtt cattgggatc aggaatatcc
    17941 atgcgccgat tcttgaagat ttaggtaaaa tagctgcttt tatgaggaga ttgtaaaatc
    18001 tccttttttg ctacaagagt ttttgaaaag agatgcgcag aagaaaagag cttccaaaga
    18061 agtcccccag agaagacttc ttgatggcta atttgaactt gaaatttggc gcactagaaa
    18121 ttttttagaa aaaagtgtaa tttttttata aaagccttta caaaaaaaat taaagtggta
    18181 taattaaatc atagaaagtg caaacgtttt cgtaaaacgt ttgcctaaat aaaaataaag
    18241 gagatttgaa tgatgaaaga tacattcaaa aatgtcttgt ctttcgaatt ttggcaaaaa
    18301 ttcggtaagg ctttgatggt agttatcgcg gttatgccgg ctgctggttt gatgatttca
    18361 atcggtaagt ctatcgtgat gattaaccca acctttgcac cacttgtcat cacaggtgga
    18421 attcttgagc aaatcggttg gggggttatc ggtaaccttc acattttgtt tgccctagcc
    18481 attggaggaa gctgggctaa agaacgtgct ggtggtgctt tcgccgctgg tcttgccttc
    18541 atcttgatta accgtatcac tggtacaatc tttggtgtat caggcgatat gttgaaaaat
    18601 ccagatgcta tggtaactac tttctttggt ggttcaatca aagttgctga ttactttatc
    18661 agtgttcttg aagctccagc cttgaacatg ggggtattcg tagggattat ctcaggtttt
    18721 gtaggggcaa ctgcttacaa caaatactac aacttccgta aacttcctga tgcactttca
    18781 ttcttcaacg ggaaacgttt cgtaccattt gtagttattc ttcgttcagc aatcgctgca
    18841 attctacttg ctgctttctg gccagtagtt caaacaggta tcaataattt cggtatctgg
    18901 attgccaact cacaagaaac tgctccaatt cttgcaccat tcttgtatgg tactttggaa
    18961 cgtttgctct tgccatttgg tcttcaccac atgttgacta tcccaatgaa ctacacagct
    19021 cttggtggta cttatgacat tttaactggt gcagctaaag gtactcaagt attcggtcaa
    19081 gacccactat ggcttgcatg ggtaacagac cttgtaaacc ttaaaggtac tgatgctagt
    19141 caataccaac acttgttaga tacagtacat ccagctcgtt tcaaagttgg acaaatgatc
    19201 ggttcattcg gtatcttgat gggtgtgatt gttgctatct accgtaatgt tgatgctgac
    19261 aagaaacata aatacaaagg tatgatgatt gcaacagctc ttgcaacatt cttgacaggg
    19321 gttactgaac caatcgaata catgttcatg ttcatcgcaa cacctatgta tcttgtttac
    19381 tcacttgttc aaggtgctgc cttcgctatg gctgacgtcg taaacctacg tatgcactca
    19441 ttcggttcaa tcgagttctt gactcgtaca cctattgcaa tcagtgctgg tattggtatg
    19501 gatatcgtta acttcgtttg ggtaactgtt ctctttgctg taatcatgta ctttatcgca
    19561 aacttcatga ttcaaaaatt caactacgca actccagggc gcaacggaaa ctacgaaact
    19621 gctgaaggtt cagaagaaac cagcagcgaa gtgaaagttg cagcaggctc tcaagctgta
    19681 aacattatca accttcttgg tggacgtgta aacatcgttg atgttgatgc atgtatgact
    19741 cgtcttcgtg taactgttaa agatgcagat aaagtaggaa atgcagagca atggaaagca
    19801 gaaggagcta tgggtcttgt gatgaaagga caaggggttc aagctatcta cggtccaaaa
    19861 gctgacattt tgaaatctga tatccaagat atccttgatt caggtgaaat cattcctgaa
    19921 actcttccaa gccaaatgac tgaagtacaa caaaacactg ttcacttcaa agatcttact
    19981 gaggaagttt actcagtagc agacggtcaa gttgttgctt tggaacaagt aaaggatcca
    20041 gtatttgctc aaaaaatgat gggtgatgga tttgcagtag aacctgcaaa tggaaacatt
    20101 gtatctccag tttcaggtac tgtatcaagc atcttcccaa caaaacatgc ttttggtatt
    20161 gtgacggaag caggtcttga agtattggtt cacattggtt tggacacagt aagtcttgaa
    20221 ggtaaaccat ttacagttca tgttgctgaa ggacaaaaag ttgcagcagg agatctcctt
    20281 gtcacagctg acttgaatgc tatccgtgca gcaggacgtg aaacttcaac agtagttgtc
    20341 ttcacaaatg gtgatgcaat taaatcagtt aaattagaaa aaacaggttc tcttgcagct
    20401 aaaacagcag ttgctaaagt agaattgtaa tatacttgag gttggaagct gtattccaac
    20461 ctcttatttt gggagaaaag aatgaaattt ttaacactca atactcatag ttggatggag
    20521 aaagaagcag aggaaaaatt ccagattttg cttgaagata ttcttgaaaa ggactatgat
    20581 ttgatttgtt tccaagaaat taatcaggag atgacctcgt cagaggtgga ggttaatgac
    20641 ctttatcaag ctttgccagc agctgagcct attcaccaag atcactatgt tagactcttg
    20701 gttgaaaagt tatctgagca agggaaaaat tactactgga cctgggccta taaccatatc
    20761 ggctatgacc gctaccacga aggtgtggct atcttgtcta aaacacctat tgaagccaga
    20821 gaaattttgg tttcagatgt ggatgatcca acagactatc atactcgccg tgttgcccta
    20881 gctgaaactg tagtcgatgg caaggagcta gcagttgcca gtgttcatct ctcttggtgg
    20941 gataaaggtt ttcaagaaga atgggcacga tttgaggctg tcttgaaaaa attgaacaag
    21001 ccacttttac tagctggaga ttttaacaac ccagcaggtc aggaaggtta ccaagctatt
    21061 ttagctagtc cattaggctt acaagacgca tttgaagttg ctcaagagaa aagtggtagc
    21121 tatactgttc cgcctgaaat tgatggctgg aaagggaaca ctgaacccct tcgaatcgat
    21181 tatgtcttta ctaccaaaga gttagcggtg gaaaatttac atgtcgtatt tgatggtaac
    21241 aagagtccac aagtgagtga tcactatggc ttgaatgcta tgttaaactg gaaataataa
    21301 ctgaaaagag gttggaacta
//
LOCUS       DAVHLA010000037        21283 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVHLA010000037 DAVHLA010000000
VERSION     DAVHLA010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21283)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21283)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21283
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.037"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            250..1695
                     /gene="cps4A"
                     /locus_tag="VVO77_001584"
     CDS             250..1695
                     /gene="cps4A"
                     /locus_tag="VVO77_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HEU5693573.1"
                     /translation="MSRRFKKSSSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     IDQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EALKNYSTIINSLQDSIQTNMPLETMINLVNAQLESGGNYKVNSQDLKGTGRTDLPSY
                     AMPDSNLYVLEIDDSSLAVVKAAIQDVMEGR"
     gene            1697..2428
                     /gene="cps4B"
                     /locus_tag="VVO77_001585"
     CDS             1697..2428
                     /gene="cps4B"
                     /locus_tag="VVO77_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4B"
                     /protein_id="HEU5693574.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRIIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPDVLDKLEKKRIPTLNDS
                     RYALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QVNSSHVLKPKLFGERYKFMKKRAQYFLEQDLVHVIASDMHNLDGRPPHMAEAYDLVT
                     QKYGEAKAQELFIDNPRKIVMDQLI"
     gene            2437..3129
                     /gene="cpsC"
                     /locus_tag="VVO77_001586"
     CDS             2437..3129
                     /gene="cpsC"
                     /locus_tag="VVO77_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HEU5693575.1"
                     /translation="MKEQNTIEIDVFQLFKTLWKRKLMILIVALVTGAGAFAYSTFIV
                     KPEYTSTTRIYVVNRDQGDKPGLTNQDLQAGSYLVKDYREIILSQNVLEKVATNLKLD
                     MPTKTLASKVKVTVPTDTRIVSISVKDKQPEEASRIANSLREVAAEKIVAVTRVSDVT
                     TLEEARPATTPSSPNVRRNSLFGFLGGAVVTVIAVLLIELLDTRVKRPEDVEDVLQIP
                     LLGVVPDLNKMK"
     gene            3139..3828
                     /locus_tag="VVO77_001587"
     CDS             3139..3828
                     /locus_tag="VVO77_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HEU5693576.1"
                     /translation="MPTLEISQAKLDFVKKAEEYYNALCTNLQLSGDDLKVFSITSVK
                     LGEGKSTTSTNIAWAFAHAGYKTLLIDGDIRNSVMLGVFKARDKITGLTEFLSGTTDL
                     SQGLCDTNVENLFVIQAGSVSPNPTALLQSKNFSTMLETLRKYFDYIIVDTAPVGVVI
                     DAAIITRKCDASILVTEVGEINRRDIQKAKEQLEHTGKPFLGVVLNKFDTSVDKYGSY
                     GNYGDYGKNKK"
     gene            3844..5211
                     /locus_tag="VVO77_001588"
     CDS             3844..5211
                     /locus_tag="VVO77_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEU5693577.1"
                     /translation="MNGKIVKSSLAIIQSFLVILLTYLLSAVREAEIVSTTAIALYIL
                     HYFVFYISDYGQDFFKRGYLIELVQTLKYILFFALAISISNFFLEDRFSISRRGMIYF
                     LTLHALLVYVLNLFIKWYWKRAYPNFKGSKKILLLTATSRVEKVLDRLIESNEVVGEL
                     VAVSVLDKPDFQHDCLKVVAEGEIVNFATHEVVDEVFINLPSEKYNIGELVSQFETMG
                     IDVTVNLNAFDRSLARNKQIREMAGLNVVTFSTTFYKTSHVIAKRIIDIMGALVGLIL
                     CGLVSIVLVPLIRKDGGSAIFAQTRIGKNGRQFTFYKFRSMCVDAEAKKRELMEQNTM
                     QGGMFKVDDDPRITKIGCFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPE
                     QKRRLSFKPGITGLWQVSGRSEIKNFDEVVKLDVAYIDDWTIWKDIEILLKTVKVVLM
                     KDGAK"
     gene            5242..6414
                     /locus_tag="VVO77_001589"
     CDS             5242..6414
                     /locus_tag="VVO77_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HEU5693578.1"
                     /translation="MKQSVYIIGSKGIPAKYGGFETFVEKLTEYQKDGNIQYYVACMR
                     ENSAKSGFTADTFEYNGAICYNIDVPNIGPARAIAYDIAAVNKAIELSKGNKDEAPIF
                     YILACRIGPFISGLKKKIRSIGGRLLVNPDGHEWLRAKWSLPVRKYWKFSEQLMVKHA
                     DLLVCDSKNIEKYIREDYKQYQPKTTYIAYGTDTTPSSLKSEDAKVRNWYREKGVSEN
                     GYYLVVGRFVPENNYETMIREFIKSKSNKDFVLITNVEQNKFYDQLLKETGFDKDLRV
                     KFVGTVYDQELLKYIRENAFAYFHGHEVGGTNPSLLEALASTKLNLLLDVGFNREVGE
                     DGAIYWKKDELAHVIEEVERFDEGDITELDEKSSQRIADAFTWEKIVSDYEEVFTV"
     gene            6411..7694
                     /locus_tag="VVO77_001590"
     CDS             6411..7694
                     /locus_tag="VVO77_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEU5693579.1"
                     /translation="MKILHYTLGFQPSRTGGLVKYAEDLMTQQATDGHEVIALYPGEI
                     SIIFRQVRIKKAENRKFQCYKIINSLPLALFGGISEPDEFMKSCDKASYRKFLKNIKV
                     DVIHIHSLIGLHKEFIEVAKELGIKTVFTSHDYYGLAPVPHFYFNGVDYSSNNTNLAW
                     NIMSSNALSVKKLRFFQVSFYPTIRKLMKMLGKNPKSKKNLVIRDITEAIDYSALRSY
                     YKAMFGLIDAYLFNSQLAKEVYEANHIIPKNNIIVSISNSSISNHNIRVSSGEKTVVA
                     YIGPDEEYKGYFDFLDIVNDLDQEKYDIKTYGHFPNEDCPPYIQQNGYFTKDTVGSVY
                     SNIDILIVPSRWKETFGLISIEALSYDVNVFVSKNVGSKDLVSEEHIFHNKDDLLKKI
                     QYVKFENVKFKTMKEHMVEIINYYERITNDNQKIN"
     gene            7672..8361
                     /locus_tag="VVO77_001591"
     CDS             7672..8361
                     /locus_tag="VVO77_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HEU5693580.1"
                     /translation="MIIKRLIKTITGKEIDLHPDIPITYILQRGFQYGLGLSRGLLRG
                     IGLGKKGKRLFIGRGVTLLAKRKLYVGNNIRIGKYVSIDCLSKDGIQIADNVKIGDYS
                     QIIGTGSVKNMGIGLKIGKNSSFSEYSLFGSAGGITIGGDVIAGQNVRFHAENHSYEV
                     LHIPIREQGVNRKGISVGDNCWIGAGAVFLDGSSIGSGCIVATNAVVTKKFPDNVIIG
                     GVPAKILMERK"
     gene            8405..9640
                     /locus_tag="VVO77_001592"
     CDS             8405..9640
                     /locus_tag="VVO77_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEU5693581.1"
                     /translation="MKIAVVGTGYVGLSISVLLAQHHHVVAVDIVKEKVELINKRISP
                     IQDDFIERYLSESNLDLVATIDAETAYKDASFIVVATPTNYDLERNFFDTSTVESVIQ
                     QVQNMNSTATIVIKSTVPVGFTDSIRKKLGISNLLFSPEFLRESRALYDNLYPSRIIV
                     GTDLSNQKLVEKAQVFSNLLVQGAIKKDIPILTMGFTEAEAVKLFANTYLALRVSYFN
                     ELDTYAEIKGLDTQKIIEGVSLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANYKNVPE
                     ELIGAIVRSNTTRKDFIANQVLKVVNYNIPEDDIPTKQMEKEVVIGIYRLTMKSNSDN
                     FRQSSIQGVMKRIKDRGVKVIIFEPTLKDSDTFFGNAVINDLEEFKVKCDVIIANRYD
                     ETLNDVKDKVYTRDIFRRD"
     gene            9591..10772
                     /locus_tag="VVO77_001593"
     CDS             9591..10772
                     /locus_tag="VVO77_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEU5693582.1"
                     /translation="MTLRIKYIHEIFLEEIDKNMKKVLIVRSGPYQVNPEGYNLQELG
                     LASAISQQGYQCDVMYYHKTKNYDQLYEKNGEQIKIFWRRGIRLFRSGIYPQILREKF
                     LNQYDKIIISEYSQIMAVLLSRIHSNVYIYNGPYYNLFKIPIIEPIYDFLFVEMLNKR
                     TKTVFCKTEKAECYLKNKGFNDCKVVGVGLDIEKFEQEEEPTEDTIELLRRMENKQNI
                     LYVGSLSKRKNTAQLIRIFNILKSKSGKKNELQLVLIGKDEDNIVEKINYSRFKDDII
                     YQPYLKNSQLQFIYPSSQLLVLPSVQEIFGMVLLEAMYFKLPVVSSASAGGETLIQDG
                     INGKIVNDFNDEHWVDCIENLLNNPLELKRLGECAHKRITEQFMWSSIARKIIETFDE
                     R"
     gene            10781..11623
                     /locus_tag="VVO77_001594"
     CDS             10781..11623
                     /locus_tag="VVO77_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU5693583.1"
                     /translation="MNFCFVILHYRTSNDTIECIKSIQKLEGDYKIVIVDNASQNGSI
                     ERVEALFANNDEIVIIKNTKNLGFAAGNNIGYAYARTQIKADMIAVLNNDIVIKQKDF
                     INRIFELYRNSQFHIAGPDIVSLVDGHHQSPVVEKINSISKANKELFKYRILRIINKI
                     GLYELMTRQPKKELNRISVADPMRYQENVILHGSFVIFSPLYVSEEECAFRPDTFMYM
                     EEPILYEYCMLKNYKTVFDPSIVIYHKEDSSTNSLYNAAYAKREFVFKNMIRSLKIYR
                     SLLK"
     gene            11665..12933
                     /locus_tag="VVO77_001595"
     CDS             11665..12933
                     /locus_tag="VVO77_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase"
                     /protein_id="HEU5693584.1"
                     /translation="MLALTIGTVVFVKKTYRTFLNPIILFVILWFIITTLSSLKLFQL
                     FEISTHTQQIILLGTSLFVIGGGIAIWFRDKFYFKVGGNSYFTTDFEINYNLFFLLGI
                     ICLFYYLPDFFSSLVSLIRGGNLNLVRQSAQDAVDTSGLKNFIGTFIVSPSAMVLEIL
                     GVLDFWSNKKGRKLFYLSLAVIFVRVIADAGRTPLFNVVIYLLLTVLANRFSEKTEKK
                     RKVSKIKIVNYGMLGSIILWLSTLSRTTTSVYRILYFYFAMSPILLEKWSSVLDSEKL
                     VTKGLVSLNGFFFSISYVLKNLFRIDYSQRVLEAYTMIANTDAIWYNIAPGLTKANAY
                     VSLFWFFYADGRLLGVLIGSLLYGTFCGYIFCRYIQQQNKKNLAMLLFIYQGVFFSFI
                     RFPFSKSNYAIAFVLLLFFAFKKKGIEKSV"
     gene            12926..13933
                     /locus_tag="VVO77_001596"
     CDS             12926..13933
                     /locus_tag="VVO77_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693585.1"
                     /translation="MFNINDQSIIYVACPYFNKTGGTELVHQLVYSINHFGGKAIVAY
                     YGSESAPNKVNPAFREYVSTFVDIKDVIDSLDNIIILPEINPDLAANLESIQKAVWWM
                     SVDNYLKRNGILGSLEHFGLLRTIKLFVKGNIKIGGYRIDKEIPHLYQSEYAKQFLLA
                     KGVKKYYRLSDYLNESYIQRSISTDTKKDVILYNPKKGIEFTRELIKQAPELTFSPIE
                     NMSTEQVKKLLSKSKVYIDFGNHPGKDRFPREAAISGCCVITGKRGSAKYYKDIPIPD
                     SYKFEDTVENIPNIIETLKSCLKNYDKHTVDFEKYQQYIKSEHDLFERDVKELFTRNR
                     G"
     gene            13938..15380
                     /locus_tag="VVO77_001597"
     CDS             13938..15380
                     /locus_tag="VVO77_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000107550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="HEU5693586.1"
                     /translation="MSTRNSLIKNSLYNVAYRMLNIIFPLVSATYTARIILASGVGEV
                     SFAQNVVSYFTTIAAMGIPNYGIREIAKTRNKAEATNKVFSELFLINGLSTLLCSIVY
                     LILILTFNSIFDNTSMYLAVGLTLVFNFLNIDWFYQGKEDYAYITKRSFSIKLISLFS
                     LFIFVRDTDDAVNYALISSLAIGGNNIFNLVNLRKYNIRFSFNNIKIRRHLKPIFVLL
                     GSVIAIEIYTMLDTTMIGAMVGTTEVGYYTNSMKLVKLLITVITAIGGVLLPRLSDYY
                     SKGEFEKLNHIVDKVFRIMLFLFLPAQVALILVAPVIMPILFGDSFIPAVLTLQLTSL
                     LICTLGFSNLFGTQILLTFGDERKLLISTILGALSNIALNLILIPVMAQNGAALASVI
                     SETIVTLTAYYYAKKRVTIRFDLGFYLPTVVSTIIMGGAIYVVMQLYIGDIEKMLFST
                     LLGGVVFLLINVFMKNPIIYEFTGIIKRKR"
     gene            15383..16483
                     /gene="glf"
                     /locus_tag="VVO77_001598"
     CDS             15383..16483
                     /gene="glf"
                     /locus_tag="VVO77_001598"
                     /EC_number="5.4.99.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
                     /protein_id="HEU5693587.1"
                     /translation="MYDYLIVGAGLSGAIFAHEATKRGKKVKVIDKRDHIGGNIYCEN
                     VEGINVHKYGAHIFHTSNKKVWDYVNQFAEFNNYINSPVANYKGSLYNLPFNMNTFYA
                     MWGTKTPQEVKDKIAEQTAGMKDVEPKNLEEQAIKLIGPDIYEKLIKGYTEKQWGRSA
                     IELPPFIIKRLPVRLTFDNNYFNDRYQGIPIGGYNVIIENMLKDVEVELGVDFFAHRE
                     ELEASANKVVFTGMIDQYFDYKHGELEYRSLRFEHEILDEENYQGNAVVNYTEREIPY
                     TRIIEHKHFEYGMQPKTVITHEYPADWKRGDEPYYPINDEKNNAMFAKYQEEAAQNDK
                     VIFCGRLADYKYYDMHVVIERALEVVEKEFSN"
     gene            16510..17379
                     /gene="rfbA"
                     /locus_tag="VVO77_001599"
     CDS             16510..17379
                     /gene="rfbA"
                     /locus_tag="VVO77_001599"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEU5693588.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLPRFKELLQDGSEFGIKLSYAEQPSPDGLAQAFIIGEEFISDDSV
                     ALILGDNIYHGSGLSKMLQKAASKESGATVFGYHVKDPERFGVVEFDQDMKAISIEEK
                     PEQPRSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLTLAQPLKKN
                     EYGQYLLRLIGEA"
     gene            17380..17973
                     /locus_tag="VVO77_001600"
     CDS             17380..17973
                     /locus_tag="VVO77_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018029578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HEU5693589.1"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENIAEAEVSEADKHHPLLKDVKPLKKEDL"
     gene            17986..19035
                     /gene="rfbB"
                     /locus_tag="VVO77_001601"
     CDS             17986..19035
                     /gene="rfbB"
                     /locus_tag="VVO77_001601"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEU5693590.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPGVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLAAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQATD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            19101..19952
                     /gene="rfbD"
                     /locus_tag="VVO77_001602"
     CDS             19101..19952
                     /gene="rfbD"
                     /locus_tag="VVO77_001602"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEU5693591.1"
                     /translation="MILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITNEEMVEK
                     VFEEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTKNVAKASEKHGATLVYISTD
                     YVFDGKKPVGQEWEVDDRPDPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGKN
                     FVFTMQNLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDT
                     TWYDFAVEILKDTDVEVKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQE
                     FYKQEVR"
     gene            20015..20485
                     /locus_tag="VVO77_001603"
     CDS             20015..20485
                     /locus_tag="VVO77_001603"
                     /inference="COORDINATES: protein motif:HMM:NF013739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding protein"
                     /protein_id="HEU5693592.1"
                     /translation="MYDYLVVGAVFAHEAALEGKKVKVIEKRNHIAGNIYTREEEGIQ
                     VHQYGAHIFHTSDKEIWDYVNQFAEFNRYTNSPVANYKGEIYNLPFNMNTFNKLWGVV
                     TPAEVQAKIDEQRAILNGKTPENLEEQAISLVGTDIYEKLIKDYTEKQWGQTNY"
     gene            20451..20627
                     /locus_tag="VVO77_001604"
     CDS             20451..20627
                     /locus_tag="VVO77_001604"
                     /inference="COORDINATES: protein motif:HMM:NF015247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693593.1"
                     /translation="MQRNSGGKPTTELPSFIIRCLPVHLTYDNNYFNDTYQGIPIGGY
                     TQIVEKCWIMKILM"
     gene            20603..21188
                     /locus_tag="VVO77_001605"
                     /pseudo
     CDS             20603..21188
                     /locus_tag="VVO77_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835598.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
BASE COUNT         6979 a         3254 c         4433 g         6617 t
ORIGIN      
        1 aagattatac cacattgtgt actatattat attgaaacta gaatagtaca catctgcttc
       61 taaaatattg ttagaaaacg atttgactgt cctgatcaat ttgtcatgtt cttatttcat
      121 tttactatat ttttggttcg cgggaagtct actaagatac ttaaagatgc agatagtgaa
      181 aataaaggtg tagacattac cgtaaaaaag tgatataatc gtatgatgtt caatgtatag
      241 gtgttaatca tgagtagacg ttttaaaaaa tcaagttcac agaaagtgaa gcgaagtgtt
      301 aatatagttt tgctgactat ttatttattg ttagtttgtt ttttattatt cttaatcttt
      361 aagtacaata tccttgcttt tagatatctt aatctagtgg taactgcgtt agtcctacta
      421 gttgccttgg tagggctact cttgattatc tataaaaaag ctgaaaaatt tactattttt
      481 ctgttggtgt tctctatcct tgtcagctct gtgtcgctct ttgcagtaca gcagtttgtt
      541 ggactgacca atcgtttaaa tgcgacttct aattactcag aatattcaat cagtgtcgct
      601 gttttagcag atagtgagat cgaaaatgtt acgcaactga cgagtgtgac agcaccgact
      661 gggactgata atgaaaatat tcaaaaacta ctagctgata tcaagtcaag tcagaatacc
      721 gatttgacga tcgaccagag ttcgtcttac ttggcagctt ataagagttt gattgcaggg
      781 gagactaagg ccattgtctt aaatagtgtc tttgaaaata tcatcgagtc agagtatcca
      841 gactatgcat cgaagataaa aaagatttat accaagggat tcactaaaaa agtagaagct
      901 cctaagacgt ctaagaatca gtctttcaat atctatgtta gtggaattga cacctatggc
      961 cctattagtt cggtgtcgcg atcagatgtc aatatcctga tgactgtcaa tcgagatacc
     1021 aagaaaatcc tcttgaccac aacgccacgt gatgcctatg taccaatcgc agatggtgga
     1081 aataatcaaa aagataaatt aacccatgcg ggcatttatg gagttgattc gtccattcac
     1141 accttagaaa atctctatgg agtggatatc aattactatg tgcgattgaa cttcacttct
     1201 ttcttgaaaa tgattgactt attgggaggg gtagatgttc ataatgatca agagttttca
     1261 gctctacatg ggaagttcca tttcccagta gggaatgtcc atctagactc tgagcaggct
     1321 ctaggttttg tacgtgaacg ctactcacta gccgatggag accgtgaccg tggtcgcaac
     1381 caacaaaagg tgattgtggc tatccttcaa aaattaacgt caaccgaagc actgaaaaat
     1441 tatagtacga tcattaatag cttgcaagat tctatccaaa caaatatgcc acttgagact
     1501 atgataaatt tggtcaatgc tcagttagaa agtggaggga attataaagt aaattctcaa
     1561 gatttaaaag ggacaggtcg gacggatctt ccttcttatg caatgccaga cagtaacctc
     1621 tatgtgttgg aaatagatga tagtagttta gctgtagtta aagcagctat acaggatgtg
     1681 atggagggta gatgaaatga tagacatcca ttcgcatatc gtttttgatg tagatgacgg
     1741 tcccaagtca agagaggaaa gcaaggctct cttggcagaa tcctacaggc aaggggtacg
     1801 aatcattgtc tctacctctc accgtcgcaa gggcatgttt gaaactccgg aagagaagat
     1861 agcagaaaac tttcttcagg ttcgggaaat agctaaggaa gtggcgagtg acttggtcat
     1921 tgcttacgga gctgaaattt actacacacc agatgttctg gataagctgg aaaaaaagcg
     1981 gattccgacc ctcaatgata gtcgttatgc cttgatagag tttagtatga acactcctta
     2041 tcgcgatatt catagcgcct tgagcaagat cttgatgttg ggaattactc cagtcattgc
     2101 ccacattgag cgctatgatg ctcttgaaaa taatgaaaaa cgcgttcgag aactgatcga
     2161 tatgggctgt tacacgcaag taaatagttc acatgtcctc aaacccaaac tttttggcga
     2221 acgttataaa ttcatgaaaa aaagagctca gtatttttta gagcaggatt tggttcatgt
     2281 cattgcaagt gatatgcaca atctagacgg tagacctcct catatggcag aagcatatga
     2341 ccttgttacc caaaaatacg gagaagcgaa ggctcaggaa ctttttatag acaatcctcg
     2401 aaaaattgta atggatcaac taatttagga gaaatgatga aagaacaaaa cacgatagaa
     2461 atcgatgtat ttcaattatt taaaaccttg tggaaacgca agctaatgat tttaatagtg
     2521 gcacttgtga caggtgcggg ggcttttgca tatagcactt ttattgttaa gccagaatat
     2581 acgagtacca cgcgaattta cgtagtgaat cgcgatcaag gagacaagcc ggggctgaca
     2641 aatcaggatt tgcaggcagg atcttatctg gtaaaagact accgtgagat tatcctttcg
     2701 cagaatgtat tggaaaaagt agcgacaaat ttgaagttgg atatgccaac aaaaacgtta
     2761 gccagcaaag ttaaagtgac tgtaccaact gacactcgta tcgtctcaat ctctgtcaaa
     2821 gataaacaac cagaagaagc cagtcgtatc gctaattctc tacgagaagt tgctgcagaa
     2881 aagatcgtcg ctgtaacgcg agtatctgat gtaacgacac ttgaagaagc gcgaccagct
     2941 acgactccct cttctccaaa tgttcgacgc aattccttgt ttggttttct tggaggagca
     3001 gtcgtaacag taattgctgt tcttttgatt gagttgctcg acacccgtgt gaaacgtcct
     3061 gaagatgtcg aagatgtact gcaaattcca cttttagggg tcgttccaga tttgaacaaa
     3121 atgaaatagg aggaagttat gccaacatta gaaatctcac aggcaaaatt ggattttgta
     3181 aaaaaggcag aggaatatta taacgctttg tgcacgaacc tacagttaag tggagatgat
     3241 ttgaaagtat tttctatcac ttctgtgaaa ctaggagaag gaaaatcaac gacttccacc
     3301 aatatcgctt gggcttttgc gcatgcaggt tacaaaacgc tgctgattga tggagatatt
     3361 cgcaattctg ttatgttagg tgtctttaaa gcaagggata agattacagg cctgacagaa
     3421 tttttatcag gaactacaga cctatcacaa gggctttgtg ataccaatgt cgaaaatctc
     3481 tttgtaattc aggctggctc tgtgtcaccg aatccgacag ctcttcttca aagtaagaat
     3541 ttcagtacaa tgcttgaaac cttgcgtaaa tattttgact acatcattgt agatactgct
     3601 cctgtcggtg tcgtgattga tgcggctatt attacgcgaa aatgcgatgc ttctatttta
     3661 gtgacggagg taggtgaaat aaatcgacgg gatattcaaa aagcaaaaga acagttggaa
     3721 cacacaggaa agccgttttt gggagttgtg ttgaataaat tcgatacttc agtagacaaa
     3781 tacggttctt atggaaatta tggagattac gggaaaaata aaaaataggt cgggggatta
     3841 gagatgaatg gaaaaatagt aaagtcttca ttggccataa tccagagttt tcttgttatt
     3901 ttattgactt atctacttag tgctgtgaga gaagcggaga ttgtttcaac aacagctatt
     3961 gcactttata tcctccatta ttttgtcttt tatatcagtg attatggaca ggatttcttt
     4021 aaaagaggat atttgattga acttgtccag acattgaaat atatcctatt ctttgcacta
     4081 gcgattagta tttctaattt tttcttagag gatcgattta gtatttccag acgaggcatg
     4141 atttacttcc tcacattaca tgctctctta gtctatgtgc taaacctatt tatcaagtgg
     4201 tattggaagc gggcttatcc caactttaaa ggaagtaaga agattctcct acttacagca
     4261 acttctcgtg tcgaaaaggt actggataga ttaatagaat caaatgaggt tgttggggag
     4321 ttggtagccg tcagtgtctt agataaacca gattttcagc atgattgttt aaaggtagta
     4381 gcagaggggg agatagtaaa ctttgcgact catgaggtgg tcgatgaagt ctttatcaat
     4441 cttccaagtg aaaaatacaa tattggagag cttgtctctc agtttgaaac gatgggaatt
     4501 gatgtaacag ttaatctaaa tgcttttgat cgtagtttgg cacgtaacaa gcaaattcgt
     4561 gagatggcag gattaaacgt tgtgactttt tctacaacat tttataagac tagtcatgta
     4621 attgctaagc ggattattga tatcatgggt gcattggtag ggctgatact atgtggttta
     4681 gtcagtattg tactggttcc tttgattcga aaggatgggg gctctgctat ttttgctcag
     4741 acgcgtatag gaaaaaatgg tcgtcagttc actttttata agtttcgctc tatgtgtgta
     4801 gatgccgagg cgaaaaaaag agaactcatg gaacaaaata ccatgcaggg tggaatgttt
     4861 aaggtggacg atgatcctcg tatcacgaaa attggttgtt ttatacggaa gactagcttg
     4921 gacgagctac cacagtttta taatgttcta aagggagata tgagtttggt tggcacacgg
     4981 ccaccaacag tggacgagta tgagcactat accccagaac aaaagcgtcg tctgagtttt
     5041 aaacctggca taacagggtt atggcaggtc agcggacgaa gtgagattaa gaattttgat
     5101 gaagttgtca aattagatgt agcctatata gacgattgga caatttggaa agatattgaa
     5161 attttattga agacagttaa agttgtattg atgaaggatg gagcgaagtg atttttgccc
     5221 ttcggtcttg ttaggagaga tatgaaacag tcagtttata tcattggttc aaaggggatt
     5281 cctgccaagt atggaggatt tgaaaccttt gttgagaaat taacagaata tcaaaaagat
     5341 ggtaacatcc aatactatgt tgcttgcatg cgcgaaaatt ctgcaaagtc aggatttaca
     5401 gcagacacat ttgagtacaa cggtgctatt tgttacaaca ttgatgtgcc taatattggt
     5461 cctgctagag ccattgctta cgatattgca gcggtcaata aggctattga attgtctaag
     5521 ggaaacaagg acgaggctcc cattttttac attctagctt gtcgtatcgg accttttatt
     5581 tctggactta agaaaaaaat tcgttcgatc ggaggccgtt tgctggtaaa tccagatggt
     5641 catgagtggc ttcgagctaa atggagcttg ccagttcgga agtattggaa attttcggaa
     5701 cagttgatgg tcaaacatgc agatttatta gtctgcgata gcaaaaatat cgaaaaatat
     5761 attcgagagg actataaaca gtatcagccc aagacgacct atatcgctta tggtacagat
     5821 actacccctt caagtctgaa atcagaagat gccaaagttc gaaactggta tcgtgaaaag
     5881 ggagtaagcg aaaatggcta ttatctagtg gtgggacgat tcgttcccga aaacaactat
     5941 gaaaccatga ttcgtgaatt tatcaagtct aagtccaata aggactttgt ccttattaca
     6001 aatgtggaac agaataaatt ttacgatcag ttgctcaagg aaacaggttt cgacaaggat
     6061 ctaagagtca aatttgtggg aacagtctat gaccaagaat tgctcaagta tatccgtgaa
     6121 aatgctttcg cctatttcca tggacatgaa gttgggggta ccaatccatc gcttcttgaa
     6181 gctttagcat ccactaaact caacttgttg ttggatgtcg gctttaaccg tgaagttggt
     6241 gaagacggag ccatttattg gaaaaaagat gagctagcgc atgtaatcga agaagtggaa
     6301 cgatttgatg aaggtgatat tacggaatta gacgaaaagt ctagccaacg aattgcggat
     6361 gcatttacgt gggaaaagat tgtgtcagat tatgaggaag tgtttactgt atgaaaattt
     6421 tgcattatac tttaggcttt caaccatcac gtacaggtgg tcttgtcaag tatgctgagg
     6481 atttgatgac tcaacaagct acagatggac atgaagtaat cgcattatat ccaggagaaa
     6541 tctcaattat atttaggcag gttagaataa aaaaagcaga gaatcgaaaa ttccaatgct
     6601 ataaaataat aaacagccta cccttggctc tatttggtgg tatttcagaa ccagatgaat
     6661 ttatgaagag ttgtgataaa gcttcttata ggaaattttt gaaaaatatt aaggtagatg
     6721 taattcacat tcactcgctt ataggattac ataaggaatt tattgaagtt gcaaaagaat
     6781 taggaattaa aactgtattt acaagccatg attattatgg tttagcgcca gttccgcatt
     6841 tttattttaa cggagtagat tatagtagta ataatactaa tttagcatgg aacatcatgt
     6901 cctctaatgc tcttagtgta aaaaaacttc gattctttca agtctctttt tacccaacaa
     6961 ttcggaaatt gatgaaaatg cttgggaaaa atccaaagtc caagaaaaac ttagtaattc
     7021 gtgatatcac ggaggctatt gattatagtg ctctccgctc ttattataaa gcaatgtttg
     7081 ggttaataga tgcttacctt ttcaatagtc agttagctaa ggaagtttat gaagctaatc
     7141 atataatacc taaaaacaat atcatagtgt ccatttctaa cagctcaata agtaatcata
     7201 atattcgtgt tagttccggt gagaaaacag tggtagctta tattgggcct gatgaggaat
     7261 ataaggggta ttttgatttt ctagatatag ttaatgattt agatcaggaa aagtatgata
     7321 ttaaaacata tggacatttt ccaaatgaag attgtccacc ttatatccaa cagaacggtt
     7381 atttcacaaa agacacggtt ggaagcgttt attccaatat agatattttg attgtgccga
     7441 gtaggtggaa ggaaacattt ggtttgatta gtatagaggc gctatcgtat gatgtgaatg
     7501 tttttgtgag caaaaatgtg ggctctaaag atttggtttc agaagaacat atctttcata
     7561 ataaagacga tttgttaaaa aaaattcaat atgtaaaatt cgagaatgta aaattcaaaa
     7621 cgatgaaaga gcatatggtg gagattataa attactatga aaggattaca aatgataatc
     7681 aaaagattaa ttaagacaat tacaggtaaa gaaattgatc ttcaccctga tatcccaata
     7741 acttacattc ttcagagagg ttttcaatac ggtttgggtc ttagtcgagg gttgttacgt
     7801 ggtattggtc taggaaaaaa aggcaaacga ttatttattg gacgtggggt aacccttctc
     7861 gcaaaacgca agttatatgt tggaaacaat atccgaatcg gcaaatatgt gagcatagat
     7921 tgcctttcaa aggatgggat ccaaattgcg gataatgtta agataggaga ttactcgcaa
     7981 ataattggta caggttcagt aaaaaatatg ggtattgggc tcaaaattgg aaagaactct
     8041 tctttctcag aatatagttt attcggttct gcaggtggga ttactatcgg aggagatgtt
     8101 attgctggac aaaatgtacg ttttcatgct gagaatcata gctacgaagt gttgcatata
     8161 ccaatcagag agcaaggtgt taatcgtaaa gggatatccg ttggtgacaa ttgctggatt
     8221 ggggcaggag ctgttttttt agatggatct agtatcggtt caggttgtat cgttgcaacg
     8281 aatgcggttg ttactaagaa atttccagat aatgtaatta ttggtggagt gccagctaaa
     8341 attttaatgg aaagaaagta gtattaaatt aattgtataa atggagggaa atgatatgtc
     8401 taaaatgaag attgctgtag ttgggacagg ttatgttggt ttatccattt ctgtgttact
     8461 tgcacaacac catcatgtag tagcagtaga tattgtaaaa gagaaagtag aattaattaa
     8521 taaaagaatt tcacctattc aggatgattt tattgaaaga tatctttcag aaagtaattt
     8581 agatttagtt gcaacaatag acgctgaaac agcttataaa gatgcctctt ttatcgtagt
     8641 agcgacacca acaaattatg acttagaaag aaattttttt gatacatcaa cagttgaatc
     8701 ggtcattcaa caagttcaga atatgaattc tacagcaact atagtaataa aatcaacagt
     8761 ccccgtgggc tttaccgatt caattcgtaa aaaattagga atttcaaatc ttctattcag
     8821 tcctgaattt ttgcgtgaat caagggcact ttatgataac ttatatccaa gtcggatcat
     8881 agttggaaca gatttaagta atcaaaaatt agttgaaaaa gcccaagttt tctctaatct
     8941 tttagtgcaa ggtgccatta aaaaagatat ccctatttta actatgggat ttactgaagc
     9001 tgaagcagtt aaattatttg ctaataccta cttagcattg cgggtatcat attttaatga
     9061 attagatact tatgcagaga tcaaagggtt agatactcaa aaaataattg aaggtgttag
     9121 tttagatcct cgtatcggaa cccattataa taatccgagc tttgggtatg gtggatattg
     9181 cttaccaaag gatactaagc aacttttagc caattataag aatgtcccag aagagcttat
     9241 tggagctata gtacgaagca atacaacacg taaagatttt attgctaatc aagttcttaa
     9301 agtggtgaat tataatatac cagaagacga tattcctact aaacagatgg agaaagaagt
     9361 tgttattgga atataccgat taactatgaa aagtaacagt gataactttc gtcagagttc
     9421 aatacaagga gttatgaaac gtattaagga tagaggagtt aaagtaatca tttttgagcc
     9481 tactctaaaa gatagtgata cattctttgg aaacgctgtt ataaatgatt tagaagagtt
     9541 caaagtaaag tgtgatgtga ttattgcaaa tcgttatgat gaaacgttga atgacgttaa
     9601 ggataaagta tatacacgag atatttttag aagagattga taaaaatatg aaaaaagtat
     9661 taattgttcg aagtggacct taccaagtca atccggaagg atataatctt caagaacttg
     9721 gtttagcctc cgctatcagt cagcaaggct accagtgtga tgtcatgtat tatcacaaaa
     9781 caaagaacta tgatcaatta tatgagaaaa atggggaaca aattaaaata ttctggagga
     9841 ggggaataag attatttaga agtggaattt atccccagat tttaagagag aaatttttga
     9901 atcagtatga taagataatt atttctgagt acagccagat tatggcagtt ttattgtcta
     9961 gaattcattc caatgtatat atttataatg gcccatacta taatctattt aagattccca
    10021 ttattgaacc tatatacgat tttctttttg tagaaatgct caataagaga accaaaacag
    10081 ttttctgcaa gacagaaaaa gcagagtgtt atcttaaaaa caaaggattc aatgattgta
    10141 aagtagtggg cgtaggtcta gatattgaga agtttgaaca agaagaggaa cctacagagg
    10201 atactataga gcttttaaga agaatggaga ataaacaaaa tattctttat gtaggttcac
    10261 tatcaaaaag aaaaaacaca gctcagttaa ttagaatttt taatatttta aaatctaaaa
    10321 gtggtaagaa aaatgaactt caattggtat tgattggtaa ggatgaggat aatattgttg
    10381 aaaaaattaa ctattcacgg tttaaagatg atattattta tcaaccttat ttaaagaatt
    10441 ctcagcttca atttatttac ccatcatcac aactacttgt gctcccgtca gttcaagaga
    10501 tttttggtat ggtattactt gaggcaatgt attttaagtt gcctgttgtt tccagtgcaa
    10561 gtgctggagg agagacactg attcaagatg gtataaacgg taaaattgtg aatgatttta
    10621 atgatgaaca ctgggtggat tgtatagaaa atctattaaa taacccattg gaattgaaac
    10681 ggcttggaga atgtgctcat aagcgcatta cggaacagtt tatgtggtct tcaattgcga
    10741 gaaaaataat tgagacattt gatgaaaggt aagacttgct atgaattttt gttttgtgat
    10801 tttgcattat cgtaccagca atgacactat agagtgtatc aaatcgattc aaaagcttga
    10861 gggagattat aaaattgtaa ttgttgataa tgcttctcaa aatggcagta tagaaagggt
    10921 agaagcctta tttgcaaata atgacgagat agttataata aaaaacacga aaaacttagg
    10981 atttgctgct ggaaataata ttggatacgc ctacgctagg actcaaataa aagctgatat
    11041 gattgctgta cttaataatg atattgttat taagcaaaaa gatttcatca atcgtatatt
    11101 tgaactctat agaaattctc agtttcatat cgctggtcca gacattgtct ctcttgtaga
    11161 tggtcatcat caaagtcctg ttgttgagaa gattaattct atatctaagg ctaataaaga
    11221 actttttaaa tatagaatct tgaggattat taataaaata ggattatatg agctgatgac
    11281 tagacagcca aaaaaagaat taaatagaat aagtgttgca gaccctatga gatatcagga
    11341 aaatgttatt ttacatggga gttttgtaat tttttcaccg ttgtatgttt cagaggagga
    11401 gtgtgctttc agaccggata cattcatgta tatggaagag cctattctat atgaatattg
    11461 catgcttaaa aattataaga cagtatttga tccttctatt gtaatttatc ataaagagga
    11521 ctcatcaaca aattcgttgt ataatgcagc atatgcaaaa agagagtttg tttttaaaaa
    11581 tatgattaga tctctaaaga tttatagaag tctattgaag tagtaaacta aggaaaggat
    11641 aataattaga aattgaatct tagtatgtta gccttgacaa taggaacagt ggtatttgtt
    11701 aaaaaaacgt ataggacgtt tctcaatccc ataattttat ttgtaatttt gtggtttatt
    11761 ataacaactt tgtcaagttt aaaactattc caacttttcg agattagtac tcacacacaa
    11821 caaattattt tgcttgggac ttctctattt gttatagggg gagggatagc aatttggttt
    11881 cgggataaat tttattttaa agttggcggt aactcatatt ttacaacaga ctttgaaatt
    11941 aattataatt tgttcttttt gctaggtatc atttgccttt tctattattt gccagatttc
    12001 ttttcctcac tggtatcatt aataagaggt gggaatttaa acttagttag acaatctgcg
    12061 caggatgcag tagataccag tggattaaag aatttcattg gaacatttat tgttagtcct
    12121 agtgccatgg tattagaaat attaggagta ttagatttct ggagcaataa aaaaggtaga
    12181 aaactatttt atcttagttt agctgtcatt tttgtaagag ttattgcaga tgctggtaga
    12241 acacctctat ttaatgttgt catatattta ttacttactg ttttagcaaa taggttctct
    12301 gaaaaaactg aaaagaagag aaaagttagt aaaattaaga tagtaaatta tggtatgcta
    12361 ggttcaatta tcttatggct atcaacttta tctaggacaa caacctccgt ttataggatt
    12421 ctttattttt atttcgcaat gtccccaata ttattagaaa agtggagtag tgtacttgat
    12481 tctgaaaaat tagtaacaaa gggtttggtt tcgttgaacg gtttcttttt ttcaatctca
    12541 tatgtactta aaaatctgtt tagaatagat tattcgcaaa gagtattaga agcatacaca
    12601 atgattgcga atactgatgc aatctggtat aatattgcac ctggtttgac caaggcaaat
    12661 gcatatgtct ctctgttttg gttcttttat gcggatggac gtttactagg agttttaata
    12721 ggatcccttc tatatggtac cttttgtggt tatatctttt gcaggtatat ccagcaacaa
    12781 aataaaaaga atttggctat gttactattt atttatcaag gtgttttttt ctcttttatt
    12841 agatttccgt tttcaaaatc aaattatgca attgcattcg tactcttatt attttttgct
    12901 tttaagaaga aaggaataga gaaaagtgtt taatatcaat gaccagtcta ttatttatgt
    12961 tgcatgtcct tattttaata aaacaggtgg aacggagctt gtccatcaat tagtttattc
    13021 tattaatcat tttgggggga aagctatcgt tgcttattat ggtagtgaaa gtgctccaaa
    13081 taaggtgaat cctgcgttta gagaatatgt ttctacgttt gttgatataa aagatgttat
    13141 tgactctctt gataatatta ttattttacc ggaaattaat ccggatttag ctgctaatct
    13201 agagtctatt caaaaagcag tatggtggat gagcgttgac aattatttga agcgtaatgg
    13261 tattttaggt tccttggaac attttggact tttacgaaca attaaattat ttgtaaaagg
    13321 aaatattaaa ataggtggat atagaataga taaagagatt ccccatcttt atcaaagtga
    13381 atacgccaag caatttcttc tagctaaagg tgtcaaaaag tactatagat tgtctgatta
    13441 tttaaacgag tcttatattc agcgatctat ttcaacagac actaaaaaag atgttattct
    13501 ttacaatcct aaaaaaggga ttgaatttac tcgtgagcta attaaacagg ctccagaatt
    13561 aacgttctct ccaattgaga atatgtcaac tgaacaggtg aaaaaattac tttcaaaaag
    13621 caaagtatat attgattttg gcaaccatcc tgggaaagat agattcccac gggaggcagc
    13681 gatatcaggt tgttgtgtga taactgggaa acgaggttct gcaaaatatt ataaggatat
    13741 tcctattcca gattcataca aatttgaaga cactgttgaa aatatcccca acattattga
    13801 gaccctgaaa tcatgcttaa aaaattatga caaacatact gttgactttg agaaatatca
    13861 acaatatatt aaatctgaac atgatttatt tgaaagagat gtgaaagaat tattcactag
    13921 gaataggggt taaggttatg tcaaccagaa attcacttat taaaaattct ctttataatg
    13981 ttgcttatag aatgttaaat atcatatttc cattagtatc cgcaacatat actgcacgga
    14041 taattttagc tagtggagtt ggggaggtct cgtttgcaca aaatgttgtt tcttacttta
    14101 caacgatagc tgctatgggt attccaaatt atggtatacg agaaattgct aaaactagaa
    14161 ataaagcaga ggctacgaat aaagtttttt cagagctatt tctgattaat ggattgtcta
    14221 cattactgtg ttctatagta tatttaattc tgattttgac attcaatagc atttttgata
    14281 atacatcaat gtatcttgct gtgggtttaa cattagtgtt taacttcctt aatatcgatt
    14341 ggttctatca aggaaaagag gactatgcat acatcacgaa acgtagtttc agtataaaac
    14401 ttatttctct ttttagttta tttatttttg ttagagatac tgacgatgca gttaactatg
    14461 cattgatttc tagcttagca attggcggga ataatatttt taatcttgtt aatttaagga
    14521 aatataatat tagatttagt tttaataata ttaagattag aagacactta aaacctattt
    14581 ttgttttgtt gggttcagtg attgctattg aaatctatac tatgctggat accactatga
    14641 ttggtgctat ggtaggaacg actgaggtag gttattatac aaattctatg aagctagtta
    14701 aattgctgat aactgtgatt accgctattg gaggagtgct tttaccacga ctaagtgatt
    14761 attattctaa gggagaattt gaaaaattaa atcacatcgt tgataaagtt tttagaatca
    14821 tgttgtttct ttttttacca gcccaagttg cattaattct agttgcacca gtaattatgc
    14881 cgattttatt tggtgatagt tttataccag cagtgttaac acttcaactt acttctttgc
    14941 ttatatgtac attagggttt agtaatttat ttgggactca aatattacta acatttggag
    15001 atgagcgaaa gcttttgatt agcacaattt taggagcgct tagtaatatc gctttgaacc
    15061 taattctgat tccagtaatg gctcaaaatg gagcagcgtt ggcatctgtg attagtgaaa
    15121 caattgttac tttaacagca tactactatg cgaaaaaacg tgtgacaatt aggtttgact
    15181 taggatttta tttgccaact gttgtttcaa caataatcat gggtggagct atatatgtag
    15241 taatgcaatt gtatattggg gatatagaaa aaatgttatt ttcaactttg ttaggaggtg
    15301 ttgtattcct tttaattaac gtttttatga agaatcctat tatatatgaa tttacaggta
    15361 ttataaagag aaagagataa ttatgtacga ctatttaatc gttggagcgg gtttgtctgg
    15421 agcaatcttc gcacacgaag ctacaaagcg tggaaaaaaa gtaaaagtga ttgataaacg
    15481 cgatcacatt ggagggaaca tatactgtga gaatgtagaa ggtatcaatg ttcataaata
    15541 tggtgcccat atcttccata cttctaataa aaaagtctgg gactacgtca atcaatttgc
    15601 tgagtttaac aactatatca actcacctgt cgcaaactat aagggaagtc tttataacct
    15661 tcctttcaat atgaatacct tctatgctat gtggggcaca aaaactccac aagaagtgaa
    15721 ggataagatt gctgagcaga cagctggtat gaaggatgtt gagccgaaaa atctggaaga
    15781 acaagctatc aagttgattg gtccggatat ctatgaaaag ttgatcaagg gttatacaga
    15841 aaagcaatgg ggacgctcag cgatagaact tcctccattt atcataaaac gccttccagt
    15901 tcgtttaacc tttgataata actattttaa tgaccgttac caagggattc ctattggtgg
    15961 ttacaatgtc atcatcgaaa atatgctgaa agatgtagaa gttgaacttg gagtagactt
    16021 ttttgctcat cgtgaagagt tggaagcatc tgctaacaaa gttgtcttca caggaatgat
    16081 cgaccaatat tttgactaca agcacggaga gttagaatac cgtagccttc gttttgagca
    16141 tgagatttta gacgaggaaa attatcaagg gaatgctgta gtgaactata cagagcgtga
    16201 gatcccttat actcgtatca tcgaacacaa acattttgaa tatggaatgc agccaaagac
    16261 agttatcacg catgaatatc cagctgactg gaagcgtggg gacgagccct actatcctat
    16321 taacgatgag aaaaataatg ctatgtttgc taaataccaa gaagaagcag cgcagaatga
    16381 taaagttatc ttttgtgggc gtttagcaga ttataagtat tacgatatgc atgtggtgat
    16441 tgaacgggcg cttgaggttg tggagaaaga atttagtaat tgaaaaacaa cgaagaaagg
    16501 ttgcttatta tgaaaggtat tattctagca ggtggttcgg gaactcgctt gtatcctttg
    16561 actcgagccg catcaaaaca acttatgccg gtttatgata aaccgatgat ttactaccca
    16621 ctttcaacat taatgttggc tgggattagg gatattttga ttatctcaac tcctcaagat
    16681 ttgcctcgtt ttaaagagct tcttcaagat ggttccgagt ttggtattaa actttcttat
    16741 gctgagcaac caagtccaga tggtttggca caagccttta tcattgggga agagtttatt
    16801 tctgatgata gcgttgcgct aatcttaggt gataatatct accatggttc tgggctttcc
    16861 aagatgctac aaaaggcagc gagtaaggag tcgggagcaa ctgtttttgg ctaccatgtc
    16921 aaggatccag agcgctttgg tgtggttgag tttgatcagg atatgaaggc tatttctatt
    16981 gaagaaaagc cagagcaacc tcgttcaaac tatgcagtta caggtctcta tttctatgat
    17041 aatgatgtag tagagattgc caagagtatt aaaccaagtc ctcgtggtga actggaaatt
    17101 acagatgtaa acaaagctta cctagatcgt ggtgatttgt ctgttgagct tatgggacgt
    17161 ggctttgctt ggctggatac tggaactcat gaaagtttac tagaggcttc acagtacatc
    17221 gaaacagtcc aacggatgca aaatgttcag gtagcaaact tagaagaaat tgcctatcgc
    17281 atgggttata tcagtcgtga agatgtattg accttagccc aaccacttaa gaaaaatgaa
    17341 tacggacagt atctgctccg tttgattgga gaagcataga tgacagataa ttttttcggt
    17401 aagacgcttg cggcacgcaa ggttgaagct attccaggca tgttggagtt tgatatcccc
    17461 gttcatggag ataatcgtgg ctggtttaaa gaaaatttcc aaaaggaaaa aatgcttcca
    17521 cttggatttc cagagtcttt ctttgcagaa ggaaaattgc aaaacaatgt atccttctca
    17581 cgtaaaaatg tccttcgagg actccacgca gagccttggg ataagtacat ctctgtagca
    17641 gatggaggga aagttctggg ttcttgggtt gatctacgcg agggtgaaac ctttgggaat
    17701 acctatcaga cagtaattga tgcaagcaag ggaatctttg ttcctcgagg cgtagctaat
    17761 ggcttccaag ttctatcaga tacagtgtca tatagctatc tggtcaatga ttactgggct
    17821 ctcgagctca aacccaagta tgcctttgtg aactacgctg atccaagcct tggtattgaa
    17881 tgggaaaata ttgcagaagc agaggtttca gaagcagata aacatcatcc cctacttaag
    17941 gatgtaaaac ctttgaaaaa agaagatttg taaaaaggaa agaatatgac tgaatacaaa
    18001 aatattatcg tgacaggtgg agctggcttt atcggttcta actttgtcca ttatgtttac
    18061 gagaactttc caggtgttca cgtgacagtc ctagataagt tgacttatgc tggaaatcgc
    18121 gcgaatattg aggaaatttt aggtaatcgt gttgagttag ttgttggtga cattgctgat
    18181 gcggagttgg tagacaagtt ggctgctcaa gcagatgcta tcgttcatta tgcagcggaa
    18241 agccacaatg ataattcgct caatgatcca tcgccattta ttcatactaa cttcatcgga
    18301 acctatactc ttttagaagc tgctcgtaag tatgatattc gcttccacca tgtatcgaca
    18361 gatgaagttt atggggatct ccctttacgc gaagatttgc caggtcatgg tgaaggacca
    18421 ggtgagaaat ttactgctga aacaaaatac aacccaagct ctccgtactc atcaaccaag
    18481 gcagcctcag atttgattgt caaagcctgg gtgcgttctt ttggagtcaa ggcaacgatt
    18541 tccaactgtt caaataacta cggtccttat caacatatcg aaaaattcat cccacgtcag
    18601 attactaaca tcctaagtgg aattaagcca aaactttacg gtgaaggtaa gaatgttcgt
    18661 gactggattc ataccaatga ccattcttca ggagtttgga caatcttgac aaaagggcaa
    18721 atcggtgaaa cctacttgat tggggctgat ggtgagaaga acaataagga agttttggaa
    18781 cttatcctta aggaaatggg acaagctacg gatgcctatg atcatgtgac tgaccgtgca
    18841 ggacatgacc ttcgctatgc gattgatgcc agcaagctcc gtgatgagtt ggggtggaaa
    18901 cctgaattta ccaactttga agctgggctc aaggcaacaa tcaagtggta tacagataac
    18961 caagaatggt ggaaagcaga aaaagaagct gttgaagcca attatgctaa gactcaggag
    19021 attattacag tataaaaagc aggaaatagc tgctttttat tgctatattg agaagagtta
    19081 catattagaa aggtctagag atgattttaa ttacaggggc aaatggccaa ttaggaacgg
    19141 aacttcgcta tttattggat gaacgtaatg aagaatacgt ggcagtagat gtggctgaga
    19201 tggacattac caatgaagaa atggttgaga aagtttttga agaggtgaaa ccgactttag
    19261 tctaccactg tgcagcctac accgctgttg atgcagcaga ggatgaagga aaagagttgg
    19321 acttcgccat caatgtgacg gggacaaaaa atgtcgcaaa agcatctgaa aagcatggtg
    19381 caactctagt ttatatttct acggactatg tctttgacgg taagaaacca gttggacaag
    19441 agtgggaagt tgatgaccga ccagatccac agacagaata tggacgcact aagcgtatgg
    19501 gggaagagtt agttgagaag catgtgtcta atttctatat tatccgtact gcctgggtat
    19561 ttggaaatta tggcaaaaac ttcgttttta ccatgcaaaa tcttgcgaaa actcataaga
    19621 ctttaacagt tgtaaatgac cagtacggtc gtccgacttg gactcgtacc ttggctgagt
    19681 tcatgaccta cctagctgaa aatcgtaagg aatttggtta ttatcatttg tcaaatgatg
    19741 cgacagaaga cacaacatgg tatgattttg cagttgaaat tttgaaagat acagatgtcg
    19801 aagtcaagcc agtagattcc agtcaatttc cagccaaagc taaacgtccg ctaaactcaa
    19861 cgatgagcct ggccaaagcc aaagctactg gatttgttat tccaacttgg caagatgcat
    19921 tgcaagaatt ttacaaacaa gaagtgagat aagtagtaga atgattttct agtctaataa
    19981 aagaggcaga taatgaactc caaaggagct taagatgtac gattatcttg ttgttggtgc
    20041 agtctttgcc catgaagcag ccttagaagg aaaaaaagta aaagttattg aaaaacgaaa
    20101 tcatatcgcg ggtaatatct atactcgtga agaggaagga attcaagttc atcaatatgg
    20161 tgctcatatc ttccatactt ctgataagga gatctgggat tatgtaaatc agtttgcaga
    20221 gtttaaccgt tataccaatt ctcctgttgc aaactataag ggtgagattt ataaccttcc
    20281 ttttaatatg aataccttca ataaactctg gggagttgta acgccagcag aagtacaggc
    20341 taagattgat gaacaacgtg ctattttaaa tggtaaaact cctgaaaatt tggaagaaca
    20401 ggcgatttct cttgtaggta cagacatcta cgaaaaatta atcaaagact atacagagaa
    20461 acagtggggg caaaccaact actgaacttc catcctttat tattcgctgt ttaccagtac
    20521 acctgaccta tgataacaac tattttaacg atacctatca agggattcca attggtggat
    20581 acactcaaat agttgaaaaa tgttggatca tgaaaatatt gatgtagaaa caaatgttga
    20641 tttctttgtg aacaaagagc aatatctgaa agattttcct aagattgtct ttactggtat
    20701 gattgatgaa ttctttgact ataagttggg cgaactagag taccgtagtc ttcgttttga
    20761 aaatgagacc ttggatatgg aaaattacca aggaaatgca gttgtgaact atacggatgc
    20821 agaaacccca tatactcgca ttattgaaca caaacatttt gagtttggga gtcaagcaaa
    20881 gactatcatt actaatagaa cattctaaaa catgggaaaa aggtgatgag ccttattatc
    20941 cagttaataa tgatcgtaat aatcatttgt ataaatcata taaaaaactt gctgatgagc
    21001 aagggaatgt tatctttggt ggccgcttag gacactatcg ttattacgat atgcaccaag
    21061 taattggagc agctttgcag tgcgtgagaa atgagttaga ttcatactca atgaaaatta
    21121 aagagcaaac taggaagcta gccgcaggtt gctcaaaaca ctgttttgag gttgcagatg
    21181 gaagctgacg cggtttgaag agattttcga agagtataaa caagtaaaac tgactaccag
    21241 ttattattta gaaatagtat taaaaattcc ttgactatat gat
//
LOCUS       DAVHLA010000038        19641 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVHLA010000038 DAVHLA010000000
VERSION     DAVHLA010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19641
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.038"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(<1..619)
                     /locus_tag="VVO77_001606"
     CDS             complement(<1..619)
                     /locus_tag="VVO77_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEU5693594.1"
                     /translation="MDFEYFYNREAERFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     KRTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDVKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQEVKNLDSNYI
                     ENNKSKYSKREYSFGENGLGTFQNVFLAAEDISDLQIIMNSQLENY"
     gene            complement(728..1246)
                     /locus_tag="VVO77_001607"
     CDS             complement(728..1246)
                     /locus_tag="VVO77_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEU5693595.1"
                     /translation="MRTYENKEELKAEIEKTFEKYISEFDNIPENLKDKRVDEVDRTP
                     AENFAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            complement(1473..2342)
                     /gene="rsmI"
                     /locus_tag="VVO77_001608"
     CDS             complement(1473..2342)
                     /gene="rsmI"
                     /locus_tag="VVO77_001608"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEU5693596.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGL
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQGVEEKDEEDLFVEIQTRIQQGVKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(2345..2662)
                     /gene="yabA"
                     /locus_tag="VVO77_001609"
     CDS             complement(2345..2662)
                     /gene="yabA"
                     /locus_tag="VVO77_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEU5693597.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(2702..3592)
                     /locus_tag="VVO77_001610"
     CDS             complement(2702..3592)
                     /locus_tag="VVO77_001610"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEU5693598.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLAHQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(3589..4227)
                     /locus_tag="VVO77_001611"
     CDS             complement(3589..4227)
                     /locus_tag="VVO77_001611"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEU5693599.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVEVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            complement(4447..5244)
                     /gene="proC"
                     /locus_tag="VVO77_001612"
     CDS             complement(4447..5244)
                     /gene="proC"
                     /locus_tag="VVO77_001612"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEU5693600.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFCQLLSKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGIVMEAVHQAYKRTQELGK"
     gene            complement(5248..6510)
                     /locus_tag="VVO77_001613"
     CDS             complement(5248..6510)
                     /locus_tag="VVO77_001613"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEU5693601.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASFLPRLEQ
                     VLVAERKEAGLEPIQFRLDSKASQFVSGQAAQAQDFDTEFLDYILAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVTGDGQIRE"
     gene            complement(6520..7650)
                     /locus_tag="VVO77_001614"
     CDS             complement(6520..7650)
                     /locus_tag="VVO77_001614"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEU5693602.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDEVKVGDNDTLSA
                     QVAAMVQADLLVLLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGVFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(7730..9607)
                     /gene="cbpE"
                     /locus_tag="VVO77_001615"
                     /gene_synonym="pce"
     CDS             complement(7730..9607)
                     /gene="cbpE"
                     /locus_tag="VVO77_001615"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HEU5693603.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAETGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSLISVVKVNG
                     KKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQTS
                     DSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRKDGFVNISTSYKPIPSFQ
                     AGWHKSVYGNWWYQAPDSTGEYAVGWNEIEGEWYYFNQTGILLQNQWKKWNNHWFYLT
                     DSGASAKNWKKIDGIWYYFNKENQMEIGWVQDKEQWYYLDVDGSMKTGWLQYMGQWYY
                     FAPSGEMKMGWVKDKETWYYMDSTGVMKTGEIEVAGQHYYLEDSGAMKQGWHKKANDW
                     YFYKTDGSRAVGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVSIEKSAT
                     IKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSESE
                     Q"
     gene            complement(9610..10497)
                     /locus_tag="VVO77_001616"
     CDS             complement(9610..10497)
                     /locus_tag="VVO77_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU5693604.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLSLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(10487..10948)
                     /locus_tag="VVO77_001617"
     CDS             complement(10487..10948)
                     /locus_tag="VVO77_001617"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEU5693605.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(10945..11853)
                     /locus_tag="VVO77_001618"
     CDS             complement(10945..11853)
                     /locus_tag="VVO77_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEU5693606.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            11846..12052
                     /locus_tag="VVO77_001619"
     CDS             11846..12052
                     /locus_tag="VVO77_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU5693607.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLHYLPFSR
                     QSYFQNQFKKISGYTPLQYRKEKR"
     gene            complement(12104..12775)
                     /locus_tag="VVO77_001620"
     CDS             complement(12104..12775)
                     /locus_tag="VVO77_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU5693608.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(12829..13050)
                     /locus_tag="VVO77_001621"
     CDS             complement(12829..13050)
                     /locus_tag="VVO77_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HEU5693609.1"
                     /translation="MILMTKNINLTNEELELIQGGADPYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            13321..14130
                     /locus_tag="VVO77_001622"
     CDS             13321..14130
                     /locus_tag="VVO77_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU5693610.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWKELSPADIEYLYDLAEKS
                     NVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(14311..15186)
                     /gene="aguB"
                     /locus_tag="VVO77_001623"
     CDS             complement(14311..15186)
                     /gene="aguB"
                     /locus_tag="VVO77_001623"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEU5693611.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(15196..16281)
                     /gene="aguA"
                     /locus_tag="VVO77_001624"
     CDS             complement(15196..16281)
                     /gene="aguA"
                     /locus_tag="VVO77_001624"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEU5693612.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRSF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALEKPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEKRYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(16278..17405)
                     /gene="nspC"
                     /locus_tag="VVO77_001625"
     CDS             complement(16278..17405)
                     /gene="nspC"
                     /locus_tag="VVO77_001625"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEU5693613.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDEDMEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(17405..18664)
                     /locus_tag="VVO77_001626"
     CDS             complement(17405..18664)
                     /locus_tag="VVO77_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEU5693614.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVKKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            complement(18661..19521)
                     /gene="speE"
                     /locus_tag="VVO77_001627"
     CDS             complement(18661..19521)
                     /gene="speE"
                     /locus_tag="VVO77_001627"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEU5693615.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDREGWKKRQLFTEYYTANLHVGSFMLPKYVE
                     DILEEEEGKK"
BASE COUNT         5665 a         4559 c         3501 g         5916 t
ORIGIN      
        1 tgtaattctc aagctgtgag ttcattatga tttgtaaatc cgatatatct tcagcagcta
       61 aaaacacatt ttgaaatgtt ccaagtccgt tttcaccaaa gctatattct ctcttactat
      121 acttactctt attattctct atatagttag agtcaaggtt cttaacctct tgaagttcat
      181 tttctttact tctgaggtta aaatctttta cttctgaagt taagtttttt gacttctgta
      241 agtcattttc ttttacctga aatatactca taaagtcttt aacataaatg atgttcggct
      301 taccaagtcc aagccttact ctttcgatca gtcctattcc tttttttaca tcaagctcat
      361 ctaatgtttt tatggcagtt ggctttgaga tatttcttct tttcataatt tcttcgacag
      421 taaaatagat aaatactctg ccttccttgt ctatccagtt attcttaaat gacattcctg
      481 tccgtttaag aagtatggaa taaaggataa ttgcttctgc tgataagccc cgaaattctt
      541 ctctatcaac taatatctcc ggtactttta agaagttaaa tctttccgct tctctgttat
      601 aaaaatattc aaagtccatg caagatcacc tcccttctta aaaatttgca aagaaaaaga
      661 cgatagtttt tcttctatcg cctttggtaa ccatttttat gaaatttttt aaagttaaaa
      721 atataattta taatactatc ttcttccatt ttctgatttt agttctgaaa gttccaaaag
      781 gtgcaaccgt atttacatga ataaacttat acacttccca agtcgctgtt ttagtcgctt
      841 catcagccca ctttctcata tgcggttcaa ataattcttc ctcactcaac gaatcaatca
      901 ttgcagagat agaattaata ttttcattta attttgcttt caactcttgc agagataaat
      961 gagcgtaggt atctgtgaac cactgatata attcaccaag ttgattccat ttaaatttat
     1021 ccgatggtgt ttttacttga agcccctttc tttcatcttc ttcccattta agaaccaagt
     1081 tggtccagcc aacctgataa gcaaagtttt ctgctggagt tctatcaact tcatcaactc
     1141 tcttatcttt taaattttct ggaatattat caaattctga aatatatttc tcaaatgttt
     1201 tctctatctc agcttttagt tcttctttat tttcgtatgt tcgcaaaaaa tcaccttctt
     1261 tctgatttat caatcctttg atttaaaatg accttatttt tctatttata ccttctagga
     1321 acgctataac tgctgctcca accatcggta ttccgtatgg gcttaataaa aaacttaata
     1381 ccaaagcttc tataccaagt gatacatctt tatattatca tcactaatta agttaaacag
     1441 aaacagacag aattattaca tcctgtctcc ctttattgtt tttcttccca gtcgtggtag
     1501 gcagcgtaga gctgactttt attccactgg taaatcttag cgacttcctt gatagcttgg
     1561 tttttcttca caccttgctg gatgcgggtt tgaatttcta cgaacaagtc ttcctcgtcc
     1621 ttttcctcca caccctgact ggcaccctca acaatgagaa gacattcgcc cttgagtggc
     1681 gtttcagcaa tgctttctaa taactcagag atagtacctc gttggtattc ttcatagatt
     1741 ttggtcaatt ccctgaccaa gacaactgag cggtcaccgt agacttctaa catattttcc
     1801 aacgtgtctg ctacacgatg aggtgattca taaaaaatct gtgtttcagg ataatctttt
     1861 ttcaagccaa aaaattgctt ctgctgacct gattttctcg gtaaaaaacc gtaaaagata
     1921 tgtggctgtg gcgctaaacc actggcaatc aaggcagaaa ttcctgcaga ggcacctgga
     1981 actgtcacaa ctgcaatttc ttcctcaata gctgccttaa ctaaatcatg accagggtct
     2041 gaaatgctag gcaaaccggc atcagagacc tgagcaatac tttgccctgc tttcaagaaa
     2101 ccaatcaaat caggaatttt ttccttggca ttgtgctcat gaaaactgat ctgcttggtg
     2161 gaaatgtcaa aatgcttgag caaaagacct gtattgcgcg tatcctcagc agcaatccaa
     2221 tctacttctt tcaaggtctg gatagctcga aaggtcatat catctagatt gccaatcggc
     2281 gttgccacta gatacagctt gccataggga gactgcccct taaaactttt ttgaatctgc
     2341 atgcctactc cctgtatagc aactcgtcac aaaacataca ttcctcgtcc tgctctcgac
     2401 gttgtccata aaaatcatta catacgtgaa atccatcacg gtaaatgcga cggacacttt
     2461 cacgaacatg cttggccttg acaggagcat ctgcttccac ctcacccaag cgttctcgca
     2521 acttactatt ttccaagcga agagctgtat tttcctctac caggctcttg agatttttct
     2581 tgatggcttc cacatcggct aaggttacca ataattgttg ggaaaaatca tccagcgcgt
     2641 caaataattc ttttttgtcc ataaaacagc cctttccttt ctttatcatt catttttgag
     2701 tttatatttc tttcaagacc agatattcca tggcattttg aaagctgaca ttagcttgcc
     2761 acatttttct agcttctagt aaatcttgta gaatcactct tactcttacc tgcaagaggt
     2821 cctgcccaca gagaacttca agaatccgta aaacctgatc ctgtttttcc ttatcatctg
     2881 ccaagttggc taatttggca acctgtagat aactttcttt tttcttagct actaaccaag
     2941 tcagcaggcg ttcactttca tcgaccaagg tccaaaaact tgcctgatgt gccaactttt
     3001 ctgcttcagc tcgcgattga ctaaacttag ctaaaagagt cgcttttttc ttaacaagtc
     3061 ccatttgttc taagagtaag ataagttttt cttcttgctt tttaaagtgg aagatctgag
     3121 tccgacttcg gattgtcggt aacatctttt cctcatcgct agtcaagaag aaaatataaa
     3181 cttcactctg gggttcttcg atgaccttga gcagagaatt ggctgcgttg ggatgcattt
     3241 tatccgcttg ctcgatgata aagacctgtt gctggctttc aatccctgct tgagaaaact
     3301 gtcccaccaa ttcccgaatg cgttctgtct tgatgacctg attgactggc ttaatcaagg
     3361 tgacatctgg aaactcttcc tgttcaatca gcttgcaact tcggcatttc tcacatggta
     3421 agacgccaac tttatccgta caaaagaggc tcttagctaa aaattgcgcc atttccaagc
     3481 ttccaaagaa acctgaaaag agataggcgt gattgagctg gtcttgttct aagatacgga
     3541 caaaacggtc aaactgagct ggttgccaag cctttagttg atcttgtttc atttggccaa
     3601 gcccattccg tcaaacaaga cagccttggt agtttccaca acttgctcca aagggagact
     3661 agcatcaatc ttgacaatgc gatttccctc tttatccaga agagaaaggt agccttgacg
     3721 aactttttta tgcaagtcca acccttccaa atccaaacga ttaacctcgc ggtcactatt
     3781 agcagcaata cgagccagcc cttcttccac ctcgatgtca aaatagagtg tcaaatcggg
     3841 tttgaggcca tctgtcgcaa actgattgag ccagtcaatg gcttcaatat ctaagccacg
     3901 accaaatccc tgataggcaa cagaactatc gataaaacga tccatgatga ccaacttgcc
     3961 agcttcaagg gctggaagaa ctttttccac caaatgctgt ctgcgactgg caatatagag
     4021 aagtagctct gttttagcat ccatctgagt atgacttgga tccaaaatca cttcccgaat
     4081 cttctcccca atcaagactc cgccaggttc acgggtcgtc aacacctcta ctcctttttc
     4141 ctctaaaatt ggtagcagag cctctaaaac actggtcttg cctgctccct ctggtccctc
     4201 aagagagact aaaaatcctt ttgacatgtc taactcattt cttttttact acttctattc
     4261 tatcaaaaaa ataggggttt gtgacaatct ttttgtcttc tcatttcata ctcaatgaaa
     4321 atcaaagagc aaactaggaa gctagccgca ggctgtactt gagtacggca aggtgaagct
     4381 gacgcagttt gaatttgatt ttcgaagagt atcaaccacc ataaaagagg cagataaaac
     4441 tacctcttat ttacctagtt cttgtgttcg tttataggct tgatgaactg cctccatgac
     4501 tatgcctcga aaagcatgcg cttctaggct tgctacgcca gcaatagtcg aaccgcctgg
     4561 actacaaact tgatctttca aaactccagg atgttgctgg ctttctagga ccaattgccc
     4621 agctcctacc acagtttggg ctgccatttt caaggctgtt tctcgtggta atcccgtctg
     4681 aacacctgca tctgccaaag cctcaataaa gagatagaca aaggctggtc cacagcctgc
     4741 aagacctgtc gctgcattga ttaagctttc tcctaattca accaagagac cagccttgga
     4801 taaaagctga caaaagagct cactgtcctc agccctgcaa ttaggagaca aggcataact
     4861 aatcactcct tgcccgatag aagcaggggt attaggcatc atacgaataa ttcggtgttg
     4921 acttgggata agacttgcta gtttttctaa ggtcaatcca gctgccatcg aaatcaaaag
     4981 aagactttct cttttttcaa ggatggtctg gtattgagaa agcagttcag aaaactgagc
     5041 aggcttaact cctagaaaaa tcacatctgc ttctgcaaac atttcttcat tgctggaagc
     5101 ctgaccacca aagtctgcaa tgaaagcatc taccttagct tgactacgat tggcaaggag
     5161 aatctcatct gacgtcctag tctgcaagac agattttgcc aagctagcac ccatattccc
     5221 caaaccgata aatccaatct tcatctctta ctcccttatc tgcccatcac cagtgaccac
     5281 atacttgtag ctagtcaatt ccttcaagcc cataggacca cgcgcgtgca atttctgagt
     5341 agaaatcccc atttcacaac caagaccaaa ttgtcctcca tctgtgaaac gagttgaggc
     5401 attaacatac accgctgcag agtccacttg atctgtaaag tatgctgcag cttcagcatt
     5461 ttccgtcaca atggcatccg aatgatgggt actgtgggat tcaatatgcg caaccgcttc
     5521 ttctaaactg ctcacaacct taacagctag aatatagtct aaaaactcgg tatcaaagtc
     5581 ttgtgcttga gcagcttgac ctgaaacaaa ctggcttgct ttgctatcta ggcggaattg
     5641 aattggttcc agtccagctt ccttacgctc tgcaaccaac acttgctcca agcgaggaag
     5701 gaagcttgct gccttgtttt catgaaccag cagaacctcc atggcattac aaacagaagg
     5761 acgactggtt ttagcattgt tgatgataga cagcgccttg tcttcgtctg catccttatc
     5821 cacatagaca tggacaatcc cagtccctgt ctcgataaca ggtacaatcg cattctcaac
     5881 cactgcattg atcaagccag ctcctccacg aggaatgaga aggtctagat agcccttggc
     5941 cttcatcata gcataactac tttcacggct agtatcctcc accagttgaa tcacatttgg
     6001 atgaatagta gtcgtctcca agcccttctt caaggctgtg acaatggcat gggttgtttg
     6061 ataggcatcc ttaccactac gaagaacaac cgcatttcca ctcttaagag tcaaagcagc
     6121 cgcatcagac gtcacatttg gacggctttc atagataata ccgatgacac ccatagctac
     6181 acgttttttt gtgataacca aaccattttc aagctgactt gtttctaaaa cttcaccgat
     6241 tggatctggt aaggcaacca cttcacgaat tcctcttgcc atcgcttcta tacgatctgc
     6301 atccaaataa agacgatcca acatcacatc tgagattttc cccttagccg ctgccatatc
     6361 gagggcatta gccgctaaaa tttcctcagt agcagccact aagtgatcag ccatggctag
     6421 caaggcttgg tttttcactt cttcactagc tgtgttaatc gattttttaa cagcctgtac
     6481 ctgttcaaat tgttcttgtc tactcaccat agtttacctc taaaattctg taaaaagtag
     6541 ttggatttca ggagtaatgg aaatccagtc gtcacggtaa atcaagacac ccttggcttt
     6601 ttgagaacgc aacatatcct ccaaagcaga tgctccaaat tgcacgcgtc cttttccaag
     6661 tgattttcca ctttccttgt caaatactgt cacgatatca ccgtaagaaa agactccttc
     6721 tgcttcaacg ataccagata agagaagact ctttccatgt tgagagagag cttccgcagc
     6781 ccctttatca acccaaatag aaccttgact ctgagcatag aaggcaagcc attgtttctg
     6841 ggtacgaagc cccttctctt gagcaacaaa gtaagaacca tcctcggtct cctctgccgc
     6901 ctcaatcatg gaatctgatt tcaaggatga gcagatataa acaggaactc ctgattccgt
     6961 cgcgatagtt gcagccttga ttttggttaa cataccccca gttccgtttg acgaaccagc
     7021 tccaccagcc atatcaataa tctcacgatt gatggtctcg attctctcca agcgtttggc
     7081 tcttggatct gaattaggat ttccagtata gagaccgtcc acatctgtca agagaaccaa
     7141 aaggtctgct tggaccatcg ccgctacttg ggcacttaga gtgtcattgt ccccaacctt
     7201 gacctcatca ataacgacac tatcattctc attgatgata ggaattgccc cacggttgag
     7261 taaaaccgac aaagcctgat gggcattttt ataacgacgc ttatccacaa agtcatcttg
     7321 ggtcagcaag atttgtgcag aaacgatttg acgcaagaga agattggtcg tatattcttc
     7381 caacaaaagt ccctgcccta ccgctgctga agcctgttta tcagcaatct tagtcggacg
     7441 ctttttaaat cctaaggctc caaaaccagc cgcaatggca cctgaagaca ccaaaatcaa
     7501 ctcatgacca gcctcgtgca gcatagccaa ctgctgggta atatccttta ccttactacg
     7561 tgataaactt ccatcctcat ttgtcagaga agaagtaccc accttaaaga caatccgttt
     7621 gtatttcata gtctcactcc gattattcat atttatccat tataacatga ataacaggaa
     7681 atagaaaaga gttgatagga aaaagaaggc cctaaaacct tcttttctac tactgttctg
     7741 attccgattt gtttacactc gtttcagagc tttgtgaagt tgaggatgtc aaatcttgac
     7801 tagttgaaga atttgtaaca ctttcatgtt gactcgtttc tttattttca agatcctttt
     7861 tcactacttc tttggattct tttatttctg aatgacttgt agttttaatt gtagcagatt
     7921 tctcgatcga aacatccact aaccaggcac cacttgaatc cacagtatag ccttctggtg
     7981 tcttaccatt cacaagtaat tgaccatttt ctttcaagaa gtaccattta tccttgtcct
     8041 tgatccaacc cacagctcgt gaaccgtctg tcttgtagaa ataccaatca tttgcctttt
     8101 tatgccagcc ttgcttcata gctcctgaat cttccagata ataatgttga ccagcaactt
     8161 ctatctcacc tgtcttcatg acaccagtag aatccatata gtaccaggtt tctttatctt
     8221 ttacccagcc cattttcatt tcccctgatg gagcaaagta ataccattgc cccatatatt
     8281 gaagccatcc tgtcttcata gaaccatcaa catccaaata ataccactgc tctttatctt
     8341 gaacccaacc aatttccatc tgattttctt tgttaaaata ataccagatt ccatcaattt
     8401 tcttccaatt tttagcagaa gcaccagagt ctgtcaaata gaaccaatga ttgttccatt
     8461 ttttccattg attctgtaac aagatacccg tttggttaaa gtaataccat tcaccttcga
     8521 tttcattcca accgacagca tactctcctg tagaatcagg cgcttgatac caccagttcc
     8581 catatacact cttatgccaa ccagcttgaa aacttggaat cggcttgtag gatgttgaaa
     8641 tattgacaaa accgtctttt cgaatatcaa aaactgtcgc atcatagtct ttgctggctg
     8701 cgttgattct ctcaattcct cgttctttga gccaattaac atactcacta tcaacaccat
     8761 ttttccaagg tagactatcc gaagtttgaa caatcaaact cggactcaaa tttttaatga
     8821 aatccttggt atttgatttg ttggtatcat ggtgatgatt aaacttcatc aaatcaactt
     8881 ttccaatgag aggaccatac ttgtcttctg ctccatgaac attatctaaa tcgcccccaa
     8941 ggtaaatttt cttgccattg actttcacca cgctaatcaa ggaattgtca tcccaaattt
     9001 tctttaattc acccgatgaa tcagtttcat tttcataatt atagagctga atatccatgt
     9061 ccccaaactg aaaatgagca tccccttgtg tgatattttg aataactgaa acacctgttt
     9121 ctgcagcagt ctgtaaaacc ttatcatagc catacagatt atcccataga cgttcagaat
     9181 tagtaatacg actatcacta tatttcttaa gatagactcg gtcaactgga taggtagaca
     9241 gtaattcatc aacatttcca atatgatcac tgtgggtatg ggtcaccaaa ataaaatcaa
     9301 gtttttggac acccaattcc ttcaaacgac gaaagacacg gtctgttaga acatgcttat
     9361 aagacgtttc aattccttct ctccatggat agcgagaatc acttccatct gggaaatcat
     9421 aatcttctcc tgtatccacc atggcaaaat gtccattgct ttcaagaata atcgcatcac
     9481 tgccaccttc ttgaacattg ataaagtgga ttttatttcc tgaactttct tgagcctgaa
     9541 cattcccata ccatgacaaa cctaaaaaag cgcctacaag tgctaaacta gttaatttct
     9601 ttttcattct tactttctca atctctccaa ggtttcctta aaaatctctg ggatatctgc
     9661 tttaaattcc aaggtcttac ctgttctcgg atgagtaaaa cctaaagtct tggcatgaag
     9721 aaattgtcca tgtcctttca aagtcttgcg aggaccatag acctcatcac cagcgactgg
     9781 atggccgata taagccatgt ggacacggat ttgatgagtg cgccctgtct ccagttgcaa
     9841 ctctactaag ctataatcgc caaagcgttc caagacgtga aaacgcgtca ctgcaggctt
     9901 ccctttagca gttacagcct gtttcttacg gtctttttca ctccggccaa tcggcgcttc
     9961 aattacacca cgatcattag gcagatttcc atgaacaatc gcccaatatt tgcggagaga
    10021 ctttttatcc ttgagttctt gggcaagtgc tagatgcgca tcatcgtttt tagcaatcat
    10081 gagaagacct gacgtatcct tatcaatacg gtgaacaatc cctggacgca gaaccccatt
    10141 gatacccgac aagtccttaa tatgatacat gagggcattt actagggttc cactggtatg
    10201 accagcactc gggtgcacaa ccattccctg aggtttgtta acgacagcca catcctcatc
    10261 ttggtagact atttctagcg aaagatcctc agccacatac tctaatacct ctggttctgg
    10321 cacatggtaa gtgacgacat caccctcttg gactgtgtat ttagctttct tgacttgacc
    10381 attgaccaag acctggcctg atttaatttg ttcattcgcg agactacgtg ataattctga
    10441 caaatctgac aaagccttat ccaaacgcag accaccagtt tcaattttaa tttccattta
    10501 tttcctcttt tagcattgca atcaataaaa taatcactcc aaccgtcaga tagctatctg
    10561 ccacattgaa aattgcaaag ttgataaagt caaggtggaa catatccaca acaaagccct
    10621 gactgaccct gtcaataaag tttccaagac cacccgcgat tattagagtc aaacccaaga
    10681 ccatccagaa tgagtcctcc atgtgtttat gtaaatacca aatggcacct atcacgacaa
    10741 ccagagtaat gacagcgaat aacagctgct gatcttgtaa gatagaaaag gctgcacctc
    10801 gattttgcag gtaggtcaag ctaacgaaat tgggaatcca ggagcgcact tcacccagtg
    10861 gaatctgctg gacgatatag gatttgacca actgatccag cccaattaaa agcagtacaa
    10921 tgactgccac tattgctctt tttttcatga tttcctcttt tgatcaaaat attcttgcat
    10981 gacttctacg aagagagtcc cagcttgact aagctccact tcttcacgtt taacatagac
    11041 catgcggtta tctaggttat ccttgagacg aataactgta atgccattaa cactgtcact
    11101 atctaaaaat ccagaacctg tcgcataggc gtccgtccgc tccaaaatac cattcaaggt
    11161 ggcacggtct gtcacattaa acatctgtga gctagcgctg gtatcgacaa agttctctga
    11221 ataataaagg tactcgtctt tctcttgagt gaaacgaacc gttggtaaat ccgctaaatc
    11281 ctccatgact aattcctctt tctgggctaa aggatgaccc tcacagagat aaatatgggt
    11341 atggaaagga atcaattcga tgacctccag acctaacttt tcaacccgtt gcataatccc
    11401 ctttttattt tgattgttga ggtagataat cccaatctca ctatgccctt gcgccacttc
    11461 atctaatatt tgaacagtag ttgattcaaa aatacggaag ttcttatagt caggatagcg
    11521 ctctgaaaag gccgtaatag ttggtggtaa gaagtcatag tgctggctag caacggaaaa
    11581 ttcatctttt tcttcttcag gattggcata ctgattttga aaaatatcaa atcctttaac
    11641 caattcttgc gctttttcat aaaattccat cccacgacgg gtcaagaaag tccctgagct
    11701 ggtccgacgg aaaatcttaa agcccaactc tttttccaaa tcacgaacag aaatagacag
    11761 actcggctga ctaacataca tcttttcagc agcttcacga aaagtaccac tattggcaat
    11821 agccacaaca tagcgtaatt gttgaatgtt catcttctac ccccaacttc tttatctttt
    11881 cattatacca tattttagaa gttttccaaa aaggaaaaaa gaacatccta ttcttcttaa
    11941 ctatcttcac tatcttcact atctgccttt ctcacgccaa tcttattttc aaaatcaatt
    12001 caaaaaaata agtggctaca caccacttca gtatcggaaa gaaaaacgtt gactatttgt
    12061 gaaaaaagaa aatgccggaa aattccgaca tttttttagt aagctaactt cctgaaaata
    12121 ggagtaacca aacatcccag aaggcagtga tattgatgag aatatgaact agtattggat
    12181 agtagagatt tttagtcatg cgatacaata gagctaaaat cagacctcca ctagcataaa
    12241 tgaaaaaagc aagaggagtt aaagcaaaat tgatatgaat ataaccgaaa ataatagcag
    12301 aaagcaaaac atctccgtac caaggtgagt ttttgaaaaa ggttgtcata agcacacctc
    12361 gataaatcaa ttcctcagca ataggggcga tgaagcaaac gatgagcaag aaataaggga
    12421 actcctgtct ccccatcatt tctaccgttt cattcaaaga aatctgattt gaagacaggg
    12481 atatgaaata cgaaaagagg aagtcagaca tatatgaaat gatgtagccc agtaaaaggt
    12541 agatgaagta cctcagctgc cacttgaaat gaaaaatttt ctttcctgca aaaaccagta
    12601 gatagatgac cgctaagaaa agaactccgc tctccatcaa aagcagaatc tgaaaaaatt
    12661 cacgacttgc tggtagatag ggctttgcga ggtgattgaa aactctccaa aaccaagttg
    12721 atttgtaaaa aattaaggac aatgctagta aaatttgaat agcccgtttt ttcatattaa
    12781 atcctctgtt ttctcccctt gtttcttcat attcctaata aattttactt aaaatctcgc
    12841 agcacttcct ttgcaaagat gattgcctcc tccaatatat cctaaatcat aggtgcctct
    12901 gggacaaaat ccatgaaccg gcagagttaa tactggttct atttcccaat cgtacctacc
    12961 attaggattt ttaccatagg gatctgctcc accttgtatc agctctaatt cttcatttgt
    13021 tagatttata ttttttgtca ttaaaatcat gatatatttc ctccattatt cttcagatta
    13081 gttgagtaat ctactactca tacctactta caaaaaaact attttaagct agttttttta
    13141 tgcttgtcta gttgcaatat tgacaagttt agtatatcat atctttgcca aatatcctct
    13201 tcaaatcttg aattgtcatc gaaacgtcct aaactgcaaa atcaattagt ctcaagcttt
    13261 ctatcaattt cttctccaaa atatgctata ataatagcaa aagataaaga aggaagacct
    13321 atgattaaac tactagcctt ggatatggac ggcaccctcc tcaatgaagc caaggaaatc
    13381 ccacaagctc acattactgc tattcacaaa gccattgaaa aaggtgtcaa actggttctc
    13441 tgtacgggtc gccccctttt cggtgtcctc ccctactaca aaaaactggg gcttgacctc
    13501 cagaacgaat atgttattgt taacaacggt tgttcaactc accaaaccag tgattggggt
    13561 ctagttgact ggaaagaact gagtccagct gacatcgaat acctctatga ccttgctgaa
    13621 aagagtaatg ttcagttgac actttttgac gagtcacatt attttgttct cggtggcaag
    13681 cccaatcaag ttattgaaaa tgatgctaaa ctagtatttt cagacctgac tgaaatttct
    13741 cttgaggaag cgactagtgg aaagttccgg atgttccaag gtatgttttt aggaacaaaa
    13801 gaacaaacag acgattttga gcagcgtttt gctgaagagc tttgccaacg attcagtgga
    13861 gttcgttcgc agcctgtcat ttatgaagca atgccacttg gaacgacaaa ggctactgct
    13921 ctttcacgac tagctgagat tttgaagatt gattcctcag agattatggc catgggcgat
    13981 gctaataacg atatcgaaat gctccagttt gcagggcttg ggattgcaat gggaaatgcc
    14041 agcgattatg tcaaatctct tgcggatgcc gttacctcaa gcaacgaaga agacggcgtt
    14101 gcgcgtgcta ttgagaaata tattctataa aaaagaaaag caaatagaca gaagttactg
    14161 ctatttgctt ttttgctaat attttaaaat acggactaat caatagacaa gaatagcgaa
    14221 tcataaaaat cgatttacta gatgccatag tatcttatag ttgctaataa gaagttagtc
    14281 tagcagaatg aatctctcat ttctcccaca ctaatctgta atttgtctat acatttctgg
    14341 tcttctatct cgaaacaagc cccagtttag gcgttcactc gctcccttgt ctaggtcata
    14401 agtagctaac agaacagctt cttcttgtct ttcagctcgt tctagaatag ctcctgtttc
    14461 atccgtcata aaggaggaac cgtagaagtc aagactggaa ctctgtccgc cattttcctc
    14521 actaggagta acctcctcta aaccataacg attggctgcg atgactggaa caatattcgc
    14581 tgctgcgtgc ccttgcatag tacgttgcca gtgaccacaa ctatctgtat ccaaaatcgg
    14641 ctctgaaccg atggctgttg gataaaagag caattctgcc ccattcagag caagacagcg
    14701 ggctgtttcg gggaaccatt gatcccaaca gataccgata ccaatcttag catagcgagt
    14761 attccagacc ttgaaaccag tgttaccagg cgtgaaatag aatttttctt gataataatg
    14821 gtcatctggt atgtgggtct ttcgataaac gcccagcact tccccatctg catcaataac
    14881 ggcaatagag ttatacaaga cattaccatc tttttcatag aaactgattg gtaaaacaac
    14941 ttgtagttcc ttagcaatca ccttaaaatg ctgaatggca gtattttccg ctacagattg
    15001 ggcatactgg tagtagtcat actgacgttc ctgacagaaa tagggatgtt caaacaactc
    15061 gggcaagaga ataatttggg ctccttgctc agcagcctga cgtactaaac gctctgcggt
    15121 ttggatattt gttgccacat ccttagcgca ttgcatctga atggttgcaa ctcttacatt
    15181 tctcatcttt ttctcctatt ctggaatttg ttgggtgata cagtggatat tgccaccacc
    15241 taagagaata tctctggctg gtattccgac aactttacgg tctgggaaac acttgctgag
    15301 gatatctaag gccacttggt cgtttacatc ctcaaactgt ggaaccaaga cagccttgtt
    15361 ggcgatataa aagtttacgt aggaagctgc tagtcgttca cctgcgtatc gcttttcttc
    15421 tccttcttca tagatgtagc ctggcaaatc ttcttctgtc acaacttgtc gaactgcagg
    15481 gataggcaat ttatgaatgg tgaagtgaca accttttgca tctgtttcct gttctaagag
    15541 ttcgagatct gcttttgaca tggcatactg gggatcattt tcgtcatctg tccaagctaa
    15601 aacaacctca gcaggaccaa caaaggcagc aacattatcg acgtgttcat tggtttcatc
    15661 ctgataaata ccataaggaa gccaaataac tttttcagca ccaagacttt ctaataatgt
    15721 gttttcaatc tcctctttag tcaggttagg attgcgacca ggactaagca agcaactttc
    15781 agttacgaga atagttcctt gaccatcgct atggattgcg cctccttcca gtacaaaagg
    15841 tttagcatca tagacaggct tttccaaggc ctcagcaaaa cgactggcta cttggtcatc
    15901 ctcttcataa tcttgataaa gaccatcata ggtgcctccc caagcattga aggcccaatc
    15961 cacggctaat ttcttacctt tatcattgac gagaatggtt gggccagtat cacgcgccca
    16021 ggcatcattg gtgggaatgt ctaaataaac aaccttgtct ccaagatagg attgggcttc
    16081 agatagatag gcctgctcca ccaaaagata gactctttcc ccttctgcta tggtctcgat
    16141 gatctgagta aatgatcttt tagcagcctt tccttgaaaa ggccatgatc ctggtcgagt
    16201 cggccatatc atgagggtac catgatgggg ttcgtactct gctggcatgt gatagcctaa
    16261 tttttttgga ctgtccatca tgataatctc cctttaaagt cttgatagcc aaaagctttg
    16321 agtaagctac agtctccctg ttcgtccatg agatagagac ttggcaatcc aataccatta
    16381 aaggtattat ttttgacaaa agaataaatg gccatgtctt gaaaataaag tctgtctccg
    16441 atttggactg gattttcaaa actataatca ccaatcacat cgcccgtcag acaggtatta
    16501 gaagaaagtc tgtaggtatg ggctttttcc tgtgcctcaa agccatttct caaaggtgga
    16561 cgatagggca tctcaagtac atcaggcata tggcaggtcg cagaggcgtc taaaaccaag
    16621 atttccatac cattttctac aatatctaat acctcagttg ctaaataacc cgcattaagc
    16681 gcaatggctt caccaggctc gatatagatt tcaagattgt aagtttttcg gatacgcttg
    16741 atttctgaaa tcagcaaatc cacatcgtaa ccttctcttg taatatgatg accaccaccc
    16801 atattgagcc attttacctc atgtaagtag ggaccaaact gttcttctac tgctttcaaa
    16861 gttgtttgta aatcatctgc tccctgctcg caaagggtat gaaaatgaag tccgtcaacc
    16921 aaatctagca aatcactcgg aatcttgtct atagtaactc caaagcgaga accaggtgca
    16981 caagggtcat agagcgcgtg atctccttga gttgaacact gagggttgag gcgcaaacca
    17041 acactgacac cagcctctcg acaacgagcc ccatgcttac gcaactgtct ctctgagtta
    17101 aagacgatat ggtctgttat cccaagcaat tcctccatgt cctcatcctt gaaagctggt
    17161 gcaaaaacat ggacttcacc aggaaattct tcccttgcca atttggcctc atagagtcca
    17221 ctagctgtcg tacctgatag atactggcta atcaagggat aagttttgta gagggaatat
    17281 gccttctggg caagcaagac cttgcaaccg gcctcttctt gtacatattg tagaatgcgg
    17341 caattagctt ctaacttggc caagtcaata acataggctg gtgttggtac ttgttctaac
    17401 ttcattagtc caccatttgt ggattttcaa ccacaaccca tggcaaacca tactcattca
    17461 aagcttccat gaatggatct ggatctaact cctcaaggtt atacactcca gcttgtttcc
    17521 aagttccgtt catgactaat tttgtcccaa tcatggctgg aactcctgtc gtataagaaa
    17581 tagcttgcga accaacctct gcgtaacatt cctgatggtc gcagacattg tagatataga
    17641 tagtcttttt gacaccgtct ttgacacctg taaagataca tccaatattg gttttaccta
    17701 cagtacgtgg accaaggcta gcaggatctg gaagcaaggc tttcaaaaat tgaattggaa
    17761 caatttcttg gccgttaaag ttaatggtat ccgtacgaag gagtccaaca ttttcaagac
    17821 atttcatgtg cgtcaagtaa gattgaccaa aagtcataaa gaaacgaatg cgtttgactc
    17881 caggaatgtt cttggccagc gattcgattt cttcatggtg aaggagatac atatcttttt
    17941 gtccaacttg agggaaatca tactcacgct tgatagacat agcttcgact tcgacccatt
    18001 tcccatcttc ccagtaagaa cctggcgcag aaacctcacg gagattaatt tctggattaa
    18061 agttggttgc aaatggataa ccgtggtcac cgccattaca gtctaaaatg tcgatataat
    18121 ggatttcatc aaaatagtgt ttgagggcat aagctgaaaa gacactagtt acacctgggt
    18181 caaaaccaga accaagaaga gcagtcaagc ctgcttcttt gaatttctct tgataagccc
    18241 actgccatga gtagtcaaag taggctgtaa aaccaagttc cttacaacgt ttttcgtaga
    18301 tagcacgcca ctcagggtct tctgtgtctt ctgcttcgta gttggctgta tcgatatagt
    18361 gaacacctgt tgccaaacaa gcatccataa tggttaaatc ttgataaggc agagctacat
    18421 tcaaaacagc ttctggtttg tagctttcaa tcagggcaat cacttcttca accttgtcag
    18481 catcaagtgc tgcagtttca attttagtac ttgttttgcc ttctagcttc gctttcaagt
    18541 catcgcattt tgacttggta cggctagcaa tcataatctc tgtaaatgtt tcgctatctt
    18601 gacaaatctt tgaaatagca acttgggcaa cgcccccaca accaataact agtaaacgac
    18661 tcattttttt ccttcctctt cttctaaaat gtcctcaaca tacttgggca acataaagga
    18721 tcccacgtgt aagtttgcag tgtagtattc tgtgaaaagc tggcgttttt tccaaccttc
    18781 cctgtcaaaa tctttgacag ggtggtattt tttcgatgca aatccaaaca accaatagcc
    18841 agctgggcta gttggaatat gggcctgata aacccgactg attggaaagg cttgattgac
    18901 cttgcggtgc atgcttcggc aggccgactc atcctcgtca aagaagggac tcccatgctg
    18961 gtaaatcatg atgccgtctt ccttcagagc tcgataacta ttgccgtaga attctttggt
    19021 aaagagtcct tccgtatggc caaatggatc tgtcgcatcg ttgatgataa tatcgtaatc
    19081 atcttcgcag tttcgcaaaa agcgtagccc attttggtag taaatggtaa cacgaggatc
    19141 atctagccct gcagcaaagt ctgggaaata ctcacgacag acctcgacca acatttcatc
    19201 cggttccacg atatcgattt gttccagttc aggatagagt gttaatactt gggcaacacc
    19261 gccgtcacca cccccaataa ccaatacttt ctttggattt gggtggacag ccatgggaac
    19321 gtggacggtc atttcattgt agacgaaatc atccgcatct gagaacaaga catggccatt
    19381 taaaatcagt attttcccaa aagctggcgt atccaagact tcgatatcct gccattcact
    19441 ttttccagcg taaagttgct tggctgttct cagagacaat ttgacatctg gagtatgaac
    19501 ttcagaaaac cataaatcca tctatttctc cttatattat atttagcgca gttagctact
    19561 gccaaagccc aagtggtata cttggaataa gccactgtgg attagttcat ttcctccaat
    19621 cgcttgacga tttccgaaag g
//
LOCUS       DAVHLA010000039        19140 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVHLA010000039 DAVHLA010000000
VERSION     DAVHLA010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19140)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19140)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19140
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.039"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            <1..144
                     /locus_tag="VVO77_001628"
     CDS             <1..144
                     /locus_tag="VVO77_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HEU5693616.1"
                     /translation="KERSKVENIFAKVKTFKIISTTYRNHRKRFGLRMNLSAGIINHE
                     LGF"
     gene            complement(196..558)
                     /locus_tag="VVO77_001629"
     CDS             complement(196..558)
                     /locus_tag="VVO77_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693617.1"
                     /translation="MPKTKTLAKLADVILWSFDFANDHAHAFFMDNVEWSHADSYFFS
                     FVSDDVEERYTENVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSV
                     GTSPEQYPDYDGFDYEEW"
     gene            complement(912..2792)
                     /locus_tag="VVO77_001630"
     CDS             complement(912..2792)
                     /locus_tag="VVO77_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEU5693618.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVTIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDIL
                     CPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RHAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(2786..3655)
                     /locus_tag="VVO77_001631"
     CDS             complement(2786..3655)
                     /locus_tag="VVO77_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU5693619.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILYKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLTQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQTCTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(3739..6384)
                     /locus_tag="VVO77_001632"
     CDS             complement(3739..6384)
                     /locus_tag="VVO77_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEU5693620.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKVLHPTEGYKKMAALILPSYRVEDL
                     DGHPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTACYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            complement(6475..7755)
                     /locus_tag="VVO77_001633"
     CDS             complement(6475..7755)
                     /locus_tag="VVO77_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEU5693621.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEKNWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETGQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFVELDLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSIDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            7926..10010
                     /locus_tag="VVO77_001634"
     CDS             7926..10010
                     /locus_tag="VVO77_001634"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEU5693622.1"
                     /translation="MKPLLETIDTRLGTTNKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTGQLGGDSLFHRQSSYDRDK
                     ASFQPHYLKIFSLRYQIETQLTPTCYGASIRLKQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKASAQADWENLLHRFDVIETGEANRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLKTASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIANCAKKLKNIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKENKWLDIHTEQNHSHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPNH"
     gene            complement(10050..11729)
                     /locus_tag="VVO77_001635"
     CDS             complement(10050..11729)
                     /locus_tag="VVO77_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEU5693623.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPAYG
                     NGGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGNCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELDYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIS
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGAVVEAQKIRVVITESQALPLLTKISLYKT
                     PRLSQTVAVQGLAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIQVLQFQAGESKKDLHLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            12485..13714
                     /gene="arcA"
                     /locus_tag="VVO77_001636"
     CDS             12485..13714
                     /gene="arcA"
                     /locus_tag="VVO77_001636"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEU5693624.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            13772..14788
                     /gene="argF"
                     /locus_tag="VVO77_001637"
     CDS             13772..14788
                     /gene="argF"
                     /locus_tag="VVO77_001637"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEU5693625.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            14953..15900
                     /gene="arcC"
                     /locus_tag="VVO77_001638"
     CDS             14953..15900
                     /gene="arcC"
                     /locus_tag="VVO77_001638"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEU5693626.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            16109..17620
                     /locus_tag="VVO77_001639"
     CDS             16109..17620
                     /locus_tag="VVO77_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEU5693627.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            17642..18973
                     /locus_tag="VVO77_001640"
     CDS             17642..18973
                     /locus_tag="VVO77_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEU5693628.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNDLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLTDKE
                     ELVELLTRCAQNYQLRYEEFDYLASLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            19066..>19140
                     /locus_tag="VVO77_001641"
     CDS             19066..>19140
                     /locus_tag="VVO77_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU5693629.1"
                     /translation="MKLSYEDKVQIYELRKQGQSFKQLS"
BASE COUNT         5405 a         4329 c         3937 g         5469 t
ORIGIN      
        1 aaggagagaa gcaaggttga gaacatcttt gccaaagtaa aaacgtttaa aataatttca
       61 acaacctatc gaaatcatcg taaacgcttc ggattacgaa tgaatttgag tgctggtatt
      121 atcaatcatg aactaggatt ctagttttgc aggaagtcta ttgaaatact aagcctacac
      181 agactgattt caattttacc attcttcata gtcaaaacca tcataatctg gatattgttc
      241 tggcgacgtt ccaaccgaac gtacgagata agcttcttcg tcctctgtct cgatttctct
      301 cagcacttgg cattcaaaac gccattcatc accgaagtcg aaaataaact taaatttttg
      361 tttgacactt aggctatcca gatagacatt ttctgtgtaa cgttcttcaa catcgtcact
      421 aacaaagcta aaaaagtaag aatctgcatg actccactca acattatcca tgaaaaatgc
      481 gtgagcatga tcatttgcaa aatcaaaact ccataaaatc acatctgcta gtttcgctaa
      541 cgtttttgtt tttggaatct atatatgtcg gtagcaacct tttttaaatt tgacggaaat
      601 gacccaagct tctatttctt gttttactaa ttttaagtgt agcataatac ctccaattgc
      661 tcatcgatag aattgctctt aggaaacatt cactttctgc tattttatca taagtttgtc
      721 taactgtagc atttgaaacc agataattct tctgtttcac gcgaaacacc ctgcgccaag
      781 caaggtgttc ttgtttttat actcaatgaa aatcaaagag caaactagga agctagctgc
      841 aggctgctca aaacactgtt ttgaggttgt agatggaagc tgacgtggtt tgaagagatt
      901 ttcgaagagt attaagtcgt ataaatcgtc gacgctgtcg caatggtatg ccactggtta
      961 gctgtagttg ctgcgaagtc cttgtctgcg tagaagtcag taaatggtag gatttcaact
     1021 tccagctcgt cgatgcggtc aagctgacca gccagataaa cctcgatacg gctttctgct
     1081 cgtttgatgc gttgcaagag tccgcccata cggatgtcaa ctgtatccaa accaaagacc
     1141 ttgttttctt tcagccattg gtggctaaag agggcatgga agtcttcaat ttggcttcta
     1201 agttctggta attcttgtct ggcgatttgt tgtaaacttt ctttatcatc cgcttggtag
     1261 gcatgacgaa tgcgtcgtcc cacatctact ttgctactta aaatagcatt caactgggcc
     1321 tgagtttcaa agagataagc atagtttcca gctttttctt taatgttagc aagcgtctca
     1381 gcagcctgag cgaagtgcgg tttgtcctgt tcaggtgtca tgtgttgatc aagaatcgga
     1441 caaagaatat cctgataaaa aacatagcgg ttgggattga taccgctgag attgcctggt
     1501 aggtctggta agaggttggc aagatcaatc tgcataaaat cctcaaccgt tagaccagta
     1561 ttggtcttga agtgcgcaga caaactatct aggtcattgc gatagctgag ttctgcccag
     1621 atttgcaagc ttggtaggat agagaactgg gcagtttcac caccattgtc tccccaacca
     1681 gttacgatga cttctttaat ctgattggca cggcaggctt tattagcctc gatagtcact
     1741 agacggctaa aatggttgtg aggtgtaaag ccaatccact tccaagctcc ccctgcaaat
     1801 gcaaggtcat ggctaatctt gtgatgattg cggaaattac ggttgtattt ttcctcgcta
     1861 tcctgataat aatcccagta aaccagagtc acacggtctt tgagacggtc taggtagaca
     1921 cgagtttcct ctggaatttc cacatcacgg tcgtactggc catccgctga catgagtttg
     1981 aagaacatat cactccacat ctggcagtgg aaaccatatt tgtcagcaat atccagcacg
     2041 cgctccaagt gttggcacat gaggagacta cgatccacaa caccgttcaa aatcaggtag
     2101 cgtcccaaac caaccaagtg ggcttcgtcc atcccgatat tgaccttgcg agtcttcagt
     2161 ttagacaacg tggcaaacat gccatcaatc aggtcataaa ccttttcttc gccaatgaga
     2221 agaatgtcct ctacatcacg gagctcctgg acttccttga caccccattt gacaaaggcc
     2281 gacaagtggg ccaaggtctg gatgcatggt acaaaggtca tgtcaaactg ttgggcatag
     2341 gcttcgattt cctgcaactc ctctgctgaa taagctccac ggaaatagcc aaagtaaggc
     2401 tgtccttcaa tctggtaagt gtcttccatg taaagctcaa aggttgagta gcccatgaga
     2461 gccaagacct caatcatctg cttggcagaa gccacattca gcaccgcatt tcgagaacag
     2521 tcaaccatgt aagccaaatc ttcgtaagct gcttgttcct caatctctac tttatcagct
     2581 tctgctagaa ctgttaccaa caaggataag gcacgataaa gttggtgagg tttgcggtag
     2641 gtcaattgat agtgaccttc ctcaccctcg atagagatag aggcttggtc agactgagtg
     2701 acagccactt ccacatctgg tagagaaata tgacctttta aaacctcaat agcttgcgtt
     2761 tgtttgggac taagtcctgt aaatcttacc attgcttttc ctcctgtagc cagttgacaa
     2821 gggcaccgta gagattggca tctgcgtgat aggtgcaggt ctggataact ggtgcgaccg
     2881 tgtattcttc gtaggcatcg acaaagtctt caacagcctt cttaacacct tggataaaat
     2941 ctggattttg actgatagag ccacccagac tgatgacatc tggatcgatc agatactgga
     3001 tattgagcaa gccttgcgtc agattgcggt tcatgcgctc aatggcttct tgacaaagag
     3061 cattaccagc tgcggcctct tggtaaatct tgcgaccgtc ccaatcagta tgaccagatt
     3121 tttcaatcac gtatcgtacc atattcccag ttgatgctag ttgcgaccag ttattaagtt
     3181 tttcagcagg ggcaagggtt gtcatgtagc caaattctcc acccagaccg tggcgacctc
     3241 gatgaagtct accattgata atcatggctc cgccaatccc tgtcccaatc acgacacagg
     3301 ctgcattttc aagctctgga tgagctagta gttcactgag tccaacgcag ttggcatcat
     3361 tttctaaatg gacaggtagc tgataagagc taagcgcctc ataccaagaa aagccatgga
     3421 tgtagggcac cgcactgaag ccatcaatca cacctgtctc ttgattgacc gcacctggaa
     3481 cgctcatagc aatcccactg taatcctgtt ctgacaagcg ttgatctagc cacgctagta
     3541 aatcctccaa gttttcaggc gttgaaatac ttgtcttata cagtattttc ccatcaggag
     3601 tcagactggc aaacttaatc ccagtccctc cgatatcaat cgttgcaatg gtcattgttt
     3661 ttaccataaa aaggggcgaa tcagcagtta gttcttactt tttcgcccct cctttctttt
     3721 gatgtttact ttttgaaatt aaatttcttc ttttttgatg aattctgtac gaatctcttg
     3781 tggagccaat agtcctgaat gaactggata tggtcgctca agtaagtcaa gaatggtttg
     3841 ttgatgttct gatatgcgca cattttcttg actcatatta tagtaacgga ggacatagcc
     3901 ttcttcattt tccgccactt taaaggctgt tggacaaact tgcggtatgc tgagaacaga
     3961 atggctcaag aggctaccag tcgcaaccac gcttccttcc tgtctagcaa gctgaaggct
     4021 ggtaaacggt gtctgcaagg ctttggcacg acgataggct gagaagcgtt cttgggcttg
     4081 gtggcattca agtgcaaact cgacttcaaa ctcacgcaag cattgtgctt ctggcgttgg
     4141 gaagtagccc cagtcaccta gctcacctga tgcacgcaaa atggtcacgg caatggtgtt
     4201 atccccaagg atttcgtatt cattcaatcc cttattggat acagtcaccc ctttttcatc
     4261 gtcatacaga ctgacaaaag cttgttggtg ttgaggattt tcaggatttt cccatgaagc
     4321 agctggtttg tttggtcgtg tcaccacctc atagatactt tcagaatcat tgcttggacg
     4381 cgtgttatga gtcttgacca agagacggat acggtgatcc ttggcagtgt tagtaaagcg
     4441 agtcttgaag cggatttgtg gattgtcaac gaagacagtc aactcagttt ccagaggaat
     4501 gtttgtcaat tcttctgacc gtccagcctc acgcttcata aactcgatga taccttgttg
     4561 ctcttcttct agcttttcat ccgcgctgac aggcacggtc aattcatgtt tgagcaagat
     4621 tttagcatag caagctgtgt tttccaagac ctcgtggccc ttaagttctg caaagattgg
     4681 ctctgttcct tttggttgga aatagatata ctcgtttccg atgtccccac ggtcttcaaa
     4741 gcggataaag tcttcatagg cttcgtgagt tgtcttgtca tagactgtga tgttgtcatc
     4801 cacactcacc gttacgaatg gtgtatcaat cactccgttt tggtaaatac cctcacggtg
     4861 ttcttgtttt ccttccagca attggaaggt tgtccaagaa agcggcgcta ggtgaactgg
     4921 aatggtcacg cgcacttgac gagcaatacg agcttggcgg aacttgtctt ttggtaaatc
     4981 atactcaaaa ttagctccga ggtcttcgat tgtagcctct acaggatgac catccaagtc
     5041 ctccacacgg taacttggca agataagagc agccatcttt ttgtagcctt ctgttgggtg
     5101 caataccttg aaatcacaag tcgccacatc aatcactgtg ctgacagtat cgaccttatc
     5161 atgcaagcct gtgttaatga cagtaaagag atagtcactt tgagccttat ccgtagcaat
     5221 tttacccttc cactcgttga gcaagttact tttaacaaag tttcctactt ggttgacctt
     5281 ggcaaaacgc gtttccatct cgcggtgaac ttcgtccacg ctacagccac agatactatc
     5341 atgtggcgca ttctgcaaaa gtgttttcca agcataggtc aactggtcct tgtggttgtg
     5401 tccaccagtg ataatagtca agggttctac cacttgctct aggaggttgc tattttcttg
     5461 gaaggcttgt tttaggtaaa tgcgggatga agaagtgttg gcaagtgtgt accagccatc
     5521 tgtttcctga ctggtcaact cgcctgtaac agttgataag tgttcaggaa gcgcaccttc
     5581 tacagcttga acatattcat caaaagaact atgaacaaag attacatccg ggaagagttc
     5641 atttgccaca cgaatggctt cgctcagatt tttctgtaca ggctggtggt cacagccgtt
     5701 catcatcaac cattggttgg tcgaagcgta ggcacgcaca tctgacaatt tttgtttcca
     5761 gaaggtcaag gcctcatctt tgtcaactgg gatttcattc ccattactgt accagttggc
     5821 aaagagaata cctaaaacac gactaccatc cacaccctgc cagtacattt ctgaaaactg
     5881 ggatgtaaac tgctcatctt caaggacttg gttgtcaaat ccaatcggct tcacaccacg
     5941 accaaaggcc gccacgtgaa tgcctgattt ttgaagaatt tgaggcgctt gtcccatatt
     6001 tccaaaggta tctggaaagt agccaatctg ggttgattta ccccatttgg cagcttcttg
     6061 ttgaccaatc aaggtattgc ggacattggc ttcactggag atcaagtagt catcctgcaa
     6121 gatgtaaaag ggaccaattt taagtttgcc ctcgtcaatg tagcgttgga ccttgtcgcg
     6181 attttcaggg cgaatttgta agtagtcatc aaggacaata gtttgtccat ccaagtggaa
     6241 actcttgaac tcagggtcat tttcaaagag atcaaagaga ttgtcaaaca attccaccaa
     6301 ctgcatacga tggctttcaa aaggcaagta ccactcacgg tcccagtgac tatgtgagat
     6361 aatatgtaca acaacatttt ccatgaagta aaacctcatt ctaaatttaa attttaacgt
     6421 tttaaatgta aacttgtgat tctgataaga atcggttgag ctaaagcgag ccccttagcg
     6481 aatatccaag taatccaaga ccaactcaca gaacatcatg ttagcccagg agaaccattc
     6541 acgagagtag agggtcggat catctacgtg gaagctttcg tgcatgacac ctgtaccacc
     6601 atcgcaggca accagctgat ccagcaagaa ttttttctct gccttatctc ttgttgtcaa
     6661 tccttggata gaaagggcga ttggccagat atagcgatag aaggtatgag aacttccgag
     6721 accgctagcg tattctcctt ggtagaagta tggattttca gagctcagaa tggtacggcg
     6781 agtggcttga tacacttcat catcgatcga acagtagccc agatagggcg cagctagtag
     6841 acttggtaca tttggatcat ccatgatgct ggcatttcct aggccatcta cttcaaaagc
     6901 gtaaatcttt tcgcccttgc tgttggtggt gtaagcgtag ttttcgattc cttcttggat
     6961 ttcatcctga agacgcttgg catcagcaat aacactctgg ctatcagcta ggtctaattc
     7021 gacaaagatt tcttgcacat aacccaagac tactacggca aacatattag acggaatcaa
     7081 gtaactatac tgacagcaat cgtcactcgg acgaaaagct gaccaagtca tacctgtcac
     7141 tgcaaagtca ggtccaaagc catcatttac caaggtgtct tccttacggt ccgtatctcg
     7201 gacaaaacga taaggagagt tcttgtggtc ttgttcaact gtccatagat ggagaatttc
     7261 cttagtcgct gcgacaaaag tctcatcaaa ctgaccagtc tcgccagtct ctttccagag
     7321 gagataagcc aactgcaaag gatagcaaag tgaatccacc tcatacttgc gctcccagat
     7381 ccagccgtta aggtctgtgt ggtcagtctc gtggtgccct ttccagttct tctcaatgtt
     7441 gaaggagtta gcatagggat ccttgagtac caaggtcatc tgacgtttga ccaaacctgc
     7501 aatggtctga cgcaggaggg catctctttt agctacatga aggtagggtc tgagttgggc
     7561 tgtcgaatct cgaagccaca tggcaggaat atccccagtc aagacaaaag ttgaaccatc
     7621 ttctaagatt tcaaccgtat tgtccaaggt atcggtgtag caacgctcga aaacatccac
     7681 ccactctgga tggtccttag cccgctctgc tacttcatct agccattctc taacaatttc
     7741 tttcgaataa atcatcgtgc aattccctct ttcaaacaag tttcattttc agtatatagc
     7801 ttttgagaca gaaaatacat acacaaatga tagtcatttt tctacaaaat agttatcttt
     7861 gaaactcctt ttctaaaggc cctctttttc tgatataatg tagaaaaaca gctaaaggaa
     7921 agactatgaa accactactt gaaaccatcg atacccgctt gggaactacc aacaagcatg
     7981 ccttttctcg gggaaatacc ctgccataca caggcgtgcc ttttgggatg aattactttg
     8041 tgccccagac cagtgaccag gatggatctt ggttcttcga tccgcatctg cctatctttc
     8101 aggggattcg attaactcac cagcccagtc cttggattgg ggactactct tggctccttc
     8161 tgacacctgt cacaggtcag cttgggggag acagtctctt tcaccgccaa tcttcctatg
     8221 atagggataa ggcctctttc caacctcatt atctaaagat tttctccctg cgctatcaaa
     8281 ttgaaaccca gctcacaccg acttgctacg gtgcttctat tcgtttgaag caaaagcaag
     8341 gcaaagccct ctccctctat cttcacgcag cagatgaact gacagtagag caagtagata
     8401 agcgaactct tgccctgcga caagaaggta aaactgaaac caacaaaaat tcgctaacga
     8461 tgttcactgc cctgcaaatg aacacggata ttcttgctat cagccaagaa gctggagact
     8521 ggcgaattga cttagcaagt agtcaaaccg agatgcaact agccacttct ttcatctctc
     8581 cttctcaagc tctaatcaat ctacctcaag aagattttga tagctgtaaa gcaagtgccc
     8641 aagcggattg ggaaaatctc ctccatcgtt ttgatgttat agagacagga gaggctaacc
     8701 gaaccttctt tgaccactgt ctctacagac tcttcctctt cccacagact ttttatgagg
     8761 ttgatgagtc agggcaagcc atccacatgg atctggctac tggtactgtc aagcctggtg
     8821 tcctctttag caacaatggt ttctgggata ccttccgcac caccttcccc ctctttgccc
     8881 ttatcatacc ggagcactat caacgctttt tagaaggttt cctcaatagc taccgcgata
     8941 ctggtttcct tccaaaatgg ctggctccag atgaacgggg tatgatgcca ggtacacttt
     9001 tagacggtat tatcgcagat agcgcctgca aggacatggc ccccgaccta gaaggagaac
     9061 tcttccaagc catgctcaaa acagccagca aagccgaccc tctcggcatc aatggccgcc
     9121 acggactagc ccaataccaa gaactaggtt acctctctac cgaccaccac gaaagtgtta
     9181 gccatactct agactatgcc tatagtgact tttgtatcgc caactgtgcc aaaaaactaa
     9241 aaaacataga aatcgctgaa acctacaagg ctgcttcaca aaattaccgc cagctatttg
     9301 acgctgagac aggttacatg cgagcacgag acaatcaagg aaactttcac cctgacttct
     9361 ctccttatag ttgggggcga gactacgctg aatgctctgc cattcaagct actttaggcg
     9421 ttctccacga catccctggc ttaatccaac tgatgggtgg aaaagaaacc tttagcaact
     9481 atcttttgaa agcctgtcaa gatgctcccc tctttgaaac aacaggctat ggttacgaaa
     9541 ttcacgaaat gagcgagatg gctactgctc cttttggaca aatagccatt tccaaccagc
     9601 ctagtttcca cattccttat ctcttccgct acagcgatta ccctgactac actgcccttc
     9661 ttatcaagac gctccgtcag aaagcttttc acccaagttg ggaagcctat cctggagatg
     9721 aagacaatgg tagtctctct gcttggtaca tctggtcagc tctcggattt tatccaacct
     9781 gtccaggaaa accaagctat gatctcggaa ttcctctctt tgaccatcta cgagtctacc
     9841 tagctaaaga aaataaatgg ctagatattc atactgagca aaaccacagc cattttaact
     9901 ttgtcaaaga atgccgactg gacaaaacac tcgtatcaac tattcaacac caagacctcc
     9961 taaaagctga acaactaact ttcaccctca gctggctacc aaatcactaa taaccaaaag
    10021 aacctttgca tcgcgcaaag gttcttcttt tatgaaactt ggacttgaag ttgatccaca
    10081 agctgaccat ccaccgttag gttcagatag aaatccaagg ttttatctcc tgcgaaatac
    10141 agggttggta gatgcaaatc ttttttgctt tcccctgctt ggaattgaag gacttgaatc
    10201 tcatcctgat aggcgacacc atggacacct gtccccggtt gaatcgaaat cttagcctct
    10261 aaagaggagc tactttcact acgttcaatc ctaaaatgaa gagtctctcc ctttgccaca
    10321 gctaggcttt tttctgcaaa tgctagcccc tgaacagcta ctgtttgtga taacctcgga
    10381 gttttataga gtgaaatctt ggtcaacaaa ggcaaagcct gtgattctgt aatgactaca
    10441 cgtatcttct gtgcttcaac aactgctcct cgcaagaggc gcttatgacc aactgtgaag
    10501 cccctgccaa attcctgcca gacaccatcc acctctactt gcacatggaa agcagaaata
    10561 cgttggccta acttcaaatc ttctctcaac tcaattacat caaaagtttt aggagaacct
    10621 aagtcgagtt ctaactggat gggcaagtct gcatcgcttg cccaagagct ggtctcaagg
    10681 ccgtctgtca aatggcgaca agcaaagtct gcggaaagag ctggaccaga tacctcagct
    10741 cccagagcca aatcttcttt atagagctca ttgcgatagg tcgcaaattc ataaagtcgt
    10801 tcaatatcct ttgcatcaaa gagcccagct tgattcggcg gaatattaag caagagtgga
    10861 gttcctcgcc ctactgagtg aaagtagatt tcgaccaact cctcgagaga cttaggatcc
    10921 tgatcctcat ggtagaacca gcctggacgg atggaaacat ctgcctctcc gattgaaaaa
    10981 atcgtgcccg agggatcccc gtgctgaaga tagtccagct ctgcttctgt tcctagttta
    11041 tcaggattca ccttttgcca cagtggatca cctgcatacc ctcgttcatt gccaatccat
    11101 cggatactgg tgccttctgt tgaaaaaatc aagcaattgc cctgcaggtc acgaatggtt
    11161 tcaaaccatt tttcaaattc ataattaacc ttttgcgcgc cctctcctct ggcaccatcc
    11221 atccaaacct cagcaaattt ccctccattt ccataggcag gatttgataa gatttccttc
    11281 agctgagcca gataataggc attgtagtcc gcttctcggt ccacatgata gaggggacta
    11341 tgggcatccc acggtgacag gtagaccccc atatccatat caaactctgt ggcagcttgg
    11401 gatacttcaa ggagcaagtc gccctttcct ctcctccaag gactgacctt aaccgaataa
    11461 tctgtgtgag ctgtcggata aaggacaaag ccatcgtggt gcttgaccac caaaatcaac
    11521 tttttgaagc ccgtttcctt gagcacacga acccactcac gcgcatccaa ctgactcggg
    11581 ttaaagcgct caggatcctc ctgtccagtc ccccattctt ggtcataaaa ggtattagga
    11641 ccgaagtgga taaaagctgc tagttcatct cccagataag ctagctgagt ctgacttggt
    11701 aacggtccat gcggtttgat tttcttcatc gttatatatc tccttcttta gcaacttctc
    11761 ttgttcacaa ggttatccac aggttgtgga taataaaaaa tgatctaacc gccagctctt
    11821 tccaactcca actggtaggc tcaggatttt tctcctcaat attccctctt caaacagctc
    11881 tgtcatatgg ttctgctaac acctctcaga atgctactct ccataattat tctcaggctt
    11941 ctttcaggtc attgtgtgaa gaccattcac tctccagact tttccacaga ttgtgaataa
    12001 gtgattattc taaactatca tctcgtcgac tataacaaaa aataaaaaga gggtcaataa
    12061 gataattatc tcttcctaaa tactcagaaa agattctata atttgtacaa ttgaacaaga
    12121 aatgcttctc caaaatctat cttcaaaaga atgttgcatc tttttatcct ttcacacaaa
    12181 catttctctt tatacagatc caagtgataa ccagatgata attggacact ttttggttat
    12241 ttgtgtattt tttgaaaaat tttttaaaaa aattttatat cctctttaat agaagtttat
    12301 gcatttgtat ctatgtattc tatcctatgt tatgtataat aacataaaat tgtgctaaac
    12361 atcataattt atattatttt ccgagaaatt atagccattg acattaccta ggaattgcgt
    12421 tataacatac atgtaagcgg tacccaaaat ggtgccaagt caaaattttt aaggaggaaa
    12481 atacatgtct tcacatccaa ttcaggtctt ctcagaaatt gggaaactga aaaaagttat
    12541 gttgcaccgt ccaggcaagg agttagaaaa cttgttgccg gactatcttg aaaggcttct
    12601 ttttgatgat attcctttct tggaagatgc tcaaaaagaa catgatgcat ttgcccaagc
    12661 tcttcgcgat gaaggaattg aggttctcta cctagaacaa ctcgctgctg aatcattgac
    12721 ctctccagaa atccgcgatc aatttatcga ggaatactta gacgaagcca acatccgtga
    12781 tcgtcaaacc aaggttgcta ttcgtgaatt gcttcacggc atcaaggaca accaagaatt
    12841 ggttgaaaaa acaatggctg ggattcaaaa agttgaattg ccagaaattc ctgacgaagc
    12901 taaagatcta actgacttag ttgaatcaga ttatccattt gcaattgacc cgatgccaaa
    12961 cctctatttc actcgcgacc catttgcaac aattggaaac gccgtatcgc ttaaccacat
    13021 gtttgcagac actcgtaacc gtgaaacact ctacggtaag tatatcttca aataccaccc
    13081 aatctatggc ggaaaagtgg atttggtcta caaccgtgaa gaagatacgc gtatcgaagg
    13141 tggagacgag ttagttcttt ctaaagacgt ccttgcagta ggtatctctc aacgtacaga
    13201 cgcagcttct atcgaaaaac ttttggtcaa catcttcaag aaaaatgttg gcttcaagaa
    13261 agttttggcc tttgaatttg ctaacaaccg taaattcatg cacttggata ctgtcttcac
    13321 tatggtagac tatgacaagt tcactattca cccagaaatc gaaggcgacc ttcacgttta
    13381 ctcagttact tacgaaaacg aaaaacttaa aatcgttgaa gagaaaggtg acttagctga
    13441 acttcttgct caaaaccttg gtgtagaaaa agttcatttg attcgttgcg gtggtggcaa
    13501 tatcgtagca gctgcgcgtg aacaatggaa cgacggttct aacactttga ccatcgcacc
    13561 tggtgtggta gttgtttatg accgcaatac cgtgaccaat aagattttgg aagaatacgg
    13621 gcttcgcttg attaagattc gcggaagtga attggttcgg ggccgtggtg gacctcgttg
    13681 tatgtctatg ccatttgaac gtgaagaagt gtaatcgctg ttcggcattc gtcaatagaa
    13741 aatgtaaaaa atagaaagag gaaataataa aatgacaaat tcagtattcc aaggacgcag
    13801 cttcttagca gaaaaagact ttacccgtgc agagttagaa taccttattg gtctttcagc
    13861 tcacttgaaa gatttgaaaa aacgcaatat tcaacaccac taccttgctg gcaagaatat
    13921 cgctctccta tttgaaaaaa catctactcg tactcgtgca gcctttacaa ctgcggctat
    13981 cgaccttggt gctcacccag aatacctcgg agcaaatgat attcagttgg gtaaaaaaga
    14041 atctactgaa gatactgcta aagtattggg acgtatgttt gacgggattg aattccgcgg
    14101 attcagccaa cgtatggttg aagaattggc agaattctca ggcgttccag tatggaacgg
    14161 tctaactgac gaatggcacc caactcaaat gctcgctgac tacttgactg ttcaagaaaa
    14221 cttcggtcgc ttggaaggct tgacattggt atactgtggt gatggacgta acaacgttgc
    14281 caacagcttg ctcgtaacag gtgctatcct tggtgtcaat gttcacatct tctcaccaaa
    14341 agaactcttc ccagaaaaag aaatcgttga attagcagaa ggatttgcta aagaaagtgg
    14401 cgcacatgtt ctcatcactg aagatgctga tgaagcagtt aaagatgcag acgttcttta
    14461 cacagacgtt tgggtatcaa tgggtgaaga agacaaattc gcagaacgtg tagctcttct
    14521 taaaccttac caagtcaata tggacttagt taaaaaagca ggcaatgaaa acttgatctt
    14581 cctacactgc ttgccagcat tccacgatac tcacactgtt tatggtaaag acgttgctga
    14641 aaaatttggt gtagaagaaa tggaagtaac agacgaagtc ttccgcagca agtacgctcg
    14701 ccacttcgat caagcagaaa accgtatgca cactatcaaa gctgttatgg ctgctacact
    14761 tggtaacctt tatattccta aagtataatt ttagataata aaccgtctac caacagctat
    14821 gagggctgcg actaatagct ttagtccggt cctcttttat ataatggtaa tctattattt
    14881 cttataaaat atgtgaaaaa tcattaaatt gaaatctaaa cgcattctat tgagtgtgat
    14941 aaaggagaat ttatggcaaa tcgtaaaatt gtagtagctt tgggaggaaa tgcgattctt
    15001 tcttctgacc catcagcaaa ggctcaacaa gaagctttag ttgaaacagc taagcatctt
    15061 gtaaaattga ttaaaaatgg agatgatctg attatcactc acggtaatgg acctcaagtt
    15121 gggaatctct tgctccaaca tttggcatca gactctgaaa agaaccctgc cttcccactc
    15181 gactcacttg tcgctatgac agaaggtagc atcggtttct ggttgaaaaa tgctttgcaa
    15241 aatgctctct tggatgaagg catcgaaaaa aatgttgcct ctgttgtaac gcaagttgtc
    15301 gtagataaaa atgatccagc ttttgttaac ttgagtaaac caatcggtcc tttctattca
    15361 gaagaagaag caaaagcaga agccgaaaag agcggagcga ctttcaagga agatgctggc
    15421 cgtggctggc gtaaggtcgt tgcctcacca aaacctgttg acatcaaaga aattgaaacc
    15481 atccgtactc ttttaaataa tggtcaagtc gtcgtagctg caggtggtgg cggtattccc
    15541 gtcgtcaaag aaaacaatgg acatttgact ggtgtcgaag cggttattga taaagacttc
    15601 gcttcccaac gtttggcaga attggttgat gcagacctct tcatcgtttt gacaggtgta
    15661 gattatgtat ttgttaacta caacaagcca aaccaggaaa aattggaaca tgtgaatgtt
    15721 gcccagctgg aagaatatat caaacaagat cagtttgcac caggtagcat gcttccaaaa
    15781 gtagaagcag ctatcgcttt tgtcaatggt cgtccagaag gaaaagcagt tattacttcc
    15841 cttgaaaatc taggcgcctt gattgaatct gaaagcggaa caattattga aaaaggataa
    15901 gttgttttac taataagatg tattctattt ctagtatctt tatatcaaat tagaaattat
    15961 tcttgaaaac atgtacaata tttcaaaaga tactagtttt agactttaat atggtaaaac
    16021 aaatataaat agaaagcgtt ttcttgaatg tttatttaag aaagtagttg gttttttaca
    16081 ctttgttaga catcaggagg aaaaacaaat gagtgaaaaa gctaaaaaag ggtttaagat
    16141 gccttcatct tacaccgtat tattgataat cattgctatt atggcagtgc taacttggtt
    16201 tatccctgcg ggggccttta tagaaggtat ttacgagact cagcctcaaa atccacaagg
    16261 gatttgggat gtcctcatgg caccgattcg ggctatgcta ggtactcatc cagaggaagg
    16321 ttcgctcatt aaagaaacga gcgcagcgat tgatgtagcc ttcttcatcc ttatggttgg
    16381 tggtttcctt ggcattgtca acaaaactgg tgctcttgac gtagggattg cctctatcgt
    16441 gaagaagtat aagggccgcg aaaaaatgtt aattttggta ctgatgcctt tgtttgccct
    16501 cggtggtaca acttatggta tgggtgaaga aacaatggcc ttctatccac tccttgtgcc
    16561 agttatgatg gccgttggtt ttgatagcct gactggtgtt gcaattattt tgctcggttc
    16621 tcaaatcggc tgtttagcat ctactctgaa tccatttgcg acaggtattg cttcagcgac
    16681 tgcgggagtt ggtacagggg acggtatcgt acttcgtctg atcttctggg ttaccttgac
    16741 tgctcttagt acttggtttg tttaccgtta tgcggataag attcaaaaag atccgactaa
    16801 gtcactggtt tatagtactc gcaaagaaga tttgaaacac tttaacgtag aagaatcttc
    16861 atctgtagaa tctacactta gcagcaaaca aaaatcagtt ctcttcttat ttgtgttgac
    16921 attcatcttg atggtattga gcttcattcc atggacagac cttggcgtta ccatttttga
    16981 tgactttaat gcttggttga ctggtcttcc agttattggt aatattgtcg gttcatctac
    17041 ttctgcacta ggtacttggt acttcccaga aggcgcaatg ctctttgcct ttatgggtat
    17101 cctgattggt gttatttatg gtcttaaaga agataagatt atctcttcct tcatgaatgg
    17161 tgctgctgac ttgctcagtg ttgccttgat cgtagcgatt gctcgtggta ttcaagttat
    17221 catgaacgac ggtatgatta ccgatacaat cctcaactgg ggtaaagaag gcttgagcgg
    17281 tctatcttca caagtcttta tcgttgtaac ttatatcttc tatctaccta tgtcattctt
    17341 gatcccatct tcatctggtc ttgccagcgc aactatgggt atcatggctc cacttggaga
    17401 atttgtaaat gtccgtccta gcttgattat cactgcttac caatctgctt caggtgtctt
    17461 gaacttgatt gcaccaacat ctggtattgt gatgggagct cttgcacttg gacgtatcaa
    17521 cattggtact tggtggaaat tcatgggcaa actcgtagtc gctattattg tagtgaccat
    17581 cgcccttctt ctccttggaa ccttccttcc attcctataa aatagtgagt gaggtgattc
    17641 catgaaaata gatataacaa atcaagttaa agatgaattt cttatatcat taaaaacctt
    17701 gatttcctat ccttcagtac tcaatgaagg agaaaatgga acaccttttg gacaagcaat
    17761 ccaagatgtc ctagaaaaaa ctttagagat ttgtcgagac ataggtttca ctacctatct
    17821 tgaccctaaa ggttattacg gatatgcaga aatcggtcag ggagcagagc ttctggccat
    17881 tctctgtcat ttggatgttg ttccatcagg tgatgaagca gattggcaga caccgccatt
    17941 tgaagcaact atcaaagacg gctgggtatt cggacgtggt gtccaagatg ataaaggccc
    18001 ttcgctcgca gctctctatg cagtaaaaag cttgctggac caaggtattc agttcaaaaa
    18061 gcgcgtacgc tttatctttg gtaccgatga ggaaaccctc tggcgctgca tggcacgcta
    18121 caataccatc gaagaacagg ccagcatggg ctttgcacct gactcatctt ttcctctgac
    18181 ctatgctgaa aaagggcttc tacaggtcaa acttcatggc cctggatcgg atcaactaga
    18241 gcttgaagta ggaggcgcct ttaacgttgt accagacaag gccaactacc aaggtcccct
    18301 ctatgaacag gtttgtaacg atctcaaaga agctggttat gattaccaat ccactgaaca
    18361 aaccgtaacg gttctcggag tgccaaagca tgctaaggat gctagtcaag gtatcaatgc
    18421 tgtcatccga ctagctacca ttcttgctcc tctccaagaa caccctgctc tcagctttct
    18481 tgcaacacaa gcaggtcaag acggcacagg aagacaaatc tttggtgata tagcagatga
    18541 accttctggt cacctatcct ttaatgtcgc aggtctcatg atcaatcatg aacgttctga
    18601 aatccgtatt gacattcgga ctcctgtctt aactgataag gaagaactag tagagttgct
    18661 tacaagatgt gcacaaaact accaactccg ctacgaagag tttgactatc tagcgtctct
    18721 atacgtcgca aaagacagta aactcgttag cacactgatg caaatctacc aagaaaagac
    18781 tggcgataac agtcctgcta tttcatccgg tggtgccact tttgctcgca ccatgccaaa
    18841 ttgtgtagcc ttcggcgcct tattcccagg agcgaagcag acagaacatc aggcaaatga
    18901 atgtgccgtt ctagaagatt tgtaccgtgc tatggatatt tatgccgaag ccgtctatcg
    18961 acttgcaact taatcaggca actgtttcta ccaaaaaaaa tcccgcaaaa tgaactgcac
    19021 cccaaaagtt agacagaata aatctaactt ttggggtgtt ttattatgaa attgagttat
    19081 gaagataaag ttcagatcta tgaactaaga aagcaaggac aaagcttcaa acagctttca
//
LOCUS       DAVHLA010000040        18630 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVHLA010000040 DAVHLA010000000
VERSION     DAVHLA010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18630
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.040"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            <1..206
                     /locus_tag="VVO77_001642"
     CDS             <1..206
                     /locus_tag="VVO77_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU5693630.1"
                     /translation="KSSKLKPLIAEDKAYNYALSKERSKVENIFAKVKTFKMFSTTYR
                     NHRKRFGLRMNLIAGIINHELGF"
     gene            255..719
                     /locus_tag="VVO77_001643"
     CDS             255..719
                     /locus_tag="VVO77_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HEU5693631.1"
                     /translation="MGGHPGFNCPLLDDEVYEDYYLEFEKEETCSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTSLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            876..1301
                     /gene="lacA"
                     /locus_tag="VVO77_001644"
     CDS             876..1301
                     /gene="lacA"
                     /locus_tag="VVO77_001644"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEU5693632.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            1332..1847
                     /gene="lacB"
                     /locus_tag="VVO77_001645"
     CDS             1332..1847
                     /gene="lacB"
                     /locus_tag="VVO77_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEU5693633.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            1858..2787
                     /locus_tag="VVO77_001646"
     CDS             1858..2787
                     /locus_tag="VVO77_001646"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEU5693634.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            2789..3769
                     /gene="lacD"
                     /locus_tag="VVO77_001647"
     CDS             2789..3769
                     /gene="lacD"
                     /locus_tag="VVO77_001647"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEU5693635.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQRTATSWKERV"
     gene            4175..4651
                     /locus_tag="VVO77_001648"
     CDS             4175..4651
                     /locus_tag="VVO77_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693636.1"
                     /translation="MNVDGNKFYNVSVSEDIVNAGQILEDYFYVDKFGNINLKGTPEE
                     LAKNIGISVQEASLMYEAVKELPNVYERGPVGFRFNLGPQVRGMGGWAAGAFATGYAG
                     WHLKQFAVNPVTSGFVAVISGAIGWAVKTAVENYWTVAVATVEVPFVNLVYTIDLP"
     gene            5049..5885
                     /locus_tag="VVO77_001649"
     CDS             5049..5885
                     /locus_tag="VVO77_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU5693637.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIIIGKGIAFGKRKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLKGYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            5921..6238
                     /locus_tag="VVO77_001650"
     CDS             5921..6238
                     /locus_tag="VVO77_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU5693638.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            6238..7929
                     /locus_tag="VVO77_001651"
     CDS             6238..7929
                     /locus_tag="VVO77_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU5693639.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIESGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARHFVGSSVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VEAAQNTITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQAQFD"
     gene            8138..9544
                     /gene="lacG"
                     /locus_tag="VVO77_001652"
     CDS             8138..9544
                     /gene="lacG"
                     /locus_tag="VVO77_001652"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEU5693640.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTDYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            9587..9844
                     /locus_tag="VVO77_001653"
     CDS             9587..9844
                     /locus_tag="VVO77_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEU5693641.1"
                     /translation="MFKDFIQSIYEKVYIINFEKCSQIPCLTSEELKSLGKWYVSTGK
                     EWICHSDDELEEFKNLFLNFINPEGWDTISFDSDFMPFQQS"
     gene            complement(10123..10884)
                     /locus_tag="VVO77_001654"
     CDS             complement(10123..10884)
                     /locus_tag="VVO77_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU5693642.1"
                     /translation="MLKQEKLAKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNVSNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(11066..12028)
                     /gene="nrdF"
                     /locus_tag="VVO77_001655"
     CDS             complement(11066..12028)
                     /gene="nrdF"
                     /locus_tag="VVO77_001655"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEU5693643.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(12216..14375)
                     /gene="nrdE"
                     /locus_tag="VVO77_001656"
     CDS             complement(12216..14375)
                     /gene="nrdE"
                     /locus_tag="VVO77_001656"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEU5693644.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(14456..14674)
                     /gene="nrdH"
                     /locus_tag="VVO77_001657"
     CDS             complement(14456..14674)
                     /gene="nrdH"
                     /locus_tag="VVO77_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEU5693645.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            15025..15288
                     /locus_tag="VVO77_001658"
     CDS             15025..15288
                     /locus_tag="VVO77_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEU5693646.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            15294..17027
                     /gene="ptsP"
                     /locus_tag="VVO77_001659"
     CDS             15294..17027
                     /gene="ptsP"
                     /locus_tag="VVO77_001659"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEU5693647.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            17281..>18630
                     /locus_tag="VVO77_001660"
     CDS             17281..>18630
                     /locus_tag="VVO77_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEU5693648.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEE
                     LLMKDPNYQLKDEDIISEIKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTSANDGAVAFARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRENLSNLRTYRRQNSDNTPRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLIFDPAQITSRTARGVAVPHGNHYHF
                     IPYEQMSELEERIARIIPLRYRSNHWVPDSRPEEPSPQPAPNPQPAPSNPIDEKLVKE
                     AVRKVGDGYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSD
                     "
BASE COUNT         5843 a         3348 c         3858 g         5581 t
ORIGIN      
        1 gtaaatccag caaacttaag ccgctaatag ctgaagataa agcctataac tatgcgctat
       61 ctaaggagag aagcaaggtt gagaacatct ttgccaaagt aaaaacgttt aaaatgtttt
      121 caacaaccta tcgaaatcat cgtaaacgct tcggattacg aatgaatttg attgctggta
      181 ttatcaatca tgaactagga ttctagtttt tcaggaagtc taataaagaa actagcaagg
      241 tcaggcctta ctttattggt ggacatccag gatttaattg tcctctactt gatgatgaag
      301 tctatgaaga ttattatcta gagtttgaga aagaagagac ttgctctgtt ccacgtcctt
      361 tcccagaaac aggtatgttg gatttccaag atagaagtcc atggctagag ggacaaaaag
      421 aaatagatct tagttatgat cttttcagca cagatgcagt gactttggat gaattgcaat
      481 ctcgaacaat tgcccttcgt tctcttaaac atgataaggg attgaaagtg cattttgcag
      541 aatttccaaa cctcatcatc tggtcaactt tgaacaaggg acctttcatt acctttgaac
      601 catggtctgg cttgtcaaca tcccttgaag aaggagatca tttagaagat aagaagaatg
      661 tttgtctctt agaagccaat caggttgaag aattagggtt tgagatagaa gttttataaa
      721 aaagtaaaaa ataaataaca aaaacaaaca caaactattg acttcttcaa acaatagtag
      781 tatattatgt ttgtgaggac taattgactg ttttttaaag atagccaata cactgctgga
      841 atccagcata gaaaaaataa aaaggagtat acaatatgtc tattgttatc ggtgcagatg
      901 ctgcaggttt gagattgaaa gaagttgtga aagacttctt agaaaaagaa aacttccacc
      961 ttgtggatgt tacagctgaa ggtcaagact ttgttgatgt gactctcgct gttgctgcag
     1021 aagtaaacaa agaagaacaa aaccttggta tcgtgattga tgcttatgga gctggtccat
     1081 ttatggttgc aactaagatc aaaggaatgg ttgctgcaga agtatctgac gaacgttcag
     1141 cttatatgac tcgtggccac aacaactcac gtatgatcac tatgggggca caacttgttg
     1201 gtgatgaatt ggctaaaaac atcgctaaag gatttgttaa tggtaaatac gacggtggtc
     1261 gtcaccaaat ccgggttgac atgttgaaca aaatgggcta attagattat agtaagaaag
     1321 gtaagttaaa aatgagaatt gcaattggat gtgaccacat cgtaactgat gaaaaaatgg
     1381 cggtttcaga atttttgaaa tcaaaaggat atgaagtcat tgactttggt acatatgacc
     1441 atacacggac tcactaccca atctttggta aaaaagtagg ggaagcagta actagtggtc
     1501 aagctgatct cggggtatgt atctgtggta ctggtgttgg tatcaacaac gctgtaaata
     1561 aagttccagg tgttcgttct gccttggttc gtgatatgac aacagccctt tatgctaaag
     1621 aacaattgaa cgctaacgtt atcggctttg gtggtaagat tactggtgaa ttgcttatgt
     1681 gtgatatcat cgaagctttc attcatgctg aatacaaacc atctgaagaa aacaagaaat
     1741 tgattgcgaa aattgaacac cttgaaagtc acaatgctca acaaacagac gcaaacttct
     1801 ttacagaatt ccttgaaaaa tgggatcgcg gagaatacca cgactaagag gtgacctatg
     1861 attttaacag tcacaatgaa cccatccatt gatatttcct atcccttgga tgagttgaag
     1921 attgatactg tcaatcgtgt ggtggatgta accaaaacgg ctggtggtaa gggacttaat
     1981 gttacccgag tactttcaga atttggcgat tctgttcttg ctactggttt agtgggtggc
     2041 aaacttggtg agtttttggt tgaacatatc gataatcaag taaagaaaga tttcttctca
     2101 attcagggag aaactcgtaa ctgtatcgct attctccacg gagacaacca aacagaagtt
     2161 cttgaaaaag gtcctgaagt attggaacag gaaggtcaag actttttgga acatttcaaa
     2221 aaactcttgg agtcagttga agtagtggcc atctcaggta gtctgccagc tggccttcca
     2281 gttgattact atgcgagctt ggtagaactt gctaatcaag ctggcaagcc tgtagtcttg
     2341 gactgctcag gtgcagcact tcaggctgtt cttgaatcac cccataaacc aacagtcatc
     2401 aaaccaaata atgaagaatt gtctcagctt cttggaagag aagtttctga ggatttggat
     2461 gaattaaaag aagtacttca agaacctttg tttgcaggga ttgaatggat tatcgtttca
     2521 cttggtgcca acggtacttt tgccaaacat ggtgacactt tctacaaggt agatattcct
     2581 agaattcagg tggtaaatcc tgttggatct ggagactcta ctgtggcagg aatttcttca
     2641 ggacttcttc acaaagaatc ggatgcagaa ttactcatca aggcaaatgt ccttggtatg
     2701 ctcaatgctc aagaaaaaat gactggtcat gtcaacatgg ccaactatca agctctatat
     2761 gatcaattaa tagtaaaaga ggtataaaat ggctttaaca gaacaaaaac gtgtacgctt
     2821 agaaaaactt tctgatgaaa atggtatcat ctcagctctt gcatttgacc aacgtggtgc
     2881 tttgaaacgc ctcatggctc aacaccaaac agaagaacca actgtggccc aaatggaaga
     2941 acttaaagtc ttggtagcag atgaattgac taaatacgct tcatctatgc ttcttgaccc
     3001 tgagtatgga cttccagcaa ctaaagctct tgatgaaaaa gctggtcttc tccttgctta
     3061 tgaaaaaaca ggttatgaca caacaagcac aaaacgcttg ccagactgct tggatgtttg
     3121 gtctgcaaaa cgtattaaag aagaaggtgc agatgcagtt aaattcttgc tttactatga
     3181 tgtagatagc tcagacgaac tcaatcaaga aaaacaagcc tacatcgaac gcatcggttc
     3241 tgagtgtgtg gctgaagata tcccattctt ccttgaaatc cttgcttacg atgaaaaaat
     3301 tgcggatgca ggttctgtag aatacgctaa agtaaaacca cacaaagtta tcggcgctat
     3361 gaaagtcttt tcagacccac gctttaacat tgatgttttg aaagttgaag ttcctgttaa
     3421 cattaaatat gttgaaggct tcgctgaagg tgaagtagtt tatacacgtg aagaagcagc
     3481 agccttcttc aaagcgcaag atgaagcaac gaacttgcca tacatctact tgagtgctgg
     3541 tgtatcagct aaactcttcc aagatactct tgtatttgct catgaatcag gtgcaaactt
     3601 taacggagtt ctttgtggcc gtgctacatg ggcaggatca gttgaagctt acatcaaaga
     3661 tggtgaagca gcagctcgcg aatggcttcg cacaactgga tttgaaaaca ttgacgaact
     3721 caacaaagtt cttcaaagaa cagcaacttc atggaaagaa cgcgtgtaag aaagtcctcc
     3781 tagtttagga acatgaatct aaaaaaattt aaaaaaagtt gtatgtaaag gtttacaaaa
     3841 taacttactt gtgctatact taaatcacaa gttaatatga attagaaagt aactatatga
     3901 agtataataa aaataggata tagtttattt tacgagctag gaaggaaaaa tacggaaaca
     3961 atattgccag aataaactat atttagatgc acatttcatt cattgtttta taaaaggaga
     4021 agataaacgg ctactaaaaa gagttttaaa gcgttagttg taggactagg tattgtttca
     4081 atattctcat cagccttacc tatggttagt ggttctgtat ttgcagatag tgccctaact
     4141 acagtataca gtagataaag caaatgatat tgttttgaat gttgatggga ataaatttta
     4201 taatgtttcg gtttcagaag atattgtaaa tgctggtcaa attttggaag attattttta
     4261 tgtagataaa tttggaaata taaatttaaa aggcactcct gaagagttag caaaaaatat
     4321 tggtatttct gtacaagaag caagtttgat gtatgaagct gtaaaagagt tacccaacgt
     4381 ttacgaaaga ggtcctgtag gttttcgttt caatcttggt cctcaagtga gggggatggg
     4441 tggctgggct gctggagctt tcgctactgg atatgctgga tggcatttga aacaatttgc
     4501 ggttaatcct gttacatctg gatttgttgc tgtaataagt ggtgcgattg gctgggctgt
     4561 aaaaactgct gtagaaaatt attggacagt tgctgtagct acagtagaag tgccgtttgt
     4621 gaaccttgtt tacaccatag atttacctta gaggttattt ctttatgaat cattctttta
     4681 aaaaaataac tgtattttgt tttatagttt cttgtgttct ttgtttatta gacttaatga
     4741 attttaaaaa tgtagctact tttttatttt tctgtcttcc tgtttttgtt ttgatttaca
     4801 aaaataaata aaaacagagc ctctgtttga tgaattttag aacatagtta agttttaaaa
     4861 aaagttgtat gtaaaggttt acaaaacaac cgacttgtgc tatacttaaa tcacaagtta
     4921 atacaaggtg agtgttacta agtaatatta ggcatgatca caggtgaatt agaaatcagc
     4981 tgattttcta gttcatttgt ggtcattttt tgtactcata tacctttaag atataaaagg
     5041 aggttgacat gtatcgaatt ctaaatccaa tgaatcacaa tgtctcgctt gtcagaaatg
     5101 ataagggaga agaggtgatt ataattggta aggggattgc attcggaaaa aggaaggggg
     5161 atttgattgc tgaaaatcag gttgagaaaa tctttcggat gaagaccgaa gagtccagag
     5221 aaaactttat ggctcttctc aaagatgttc cgcttgattt tatcacagtg acctatgaaa
     5281 tcattgataa gctatcaaag aaatatcatt atccgattca agagtatctc tatgtaacct
     5341 tgacagatca tatttactgt tcttatcaag ctctaactca aggaaggtac aaggatagta
     5401 atctgccgga tatttccgct aagtatcctg tcgcttttca aatcgcaaat gaagcttttg
     5461 aaatttaccg tcagaagcta gcagatcatt ttcctgagga cgagattatt cggattgctt
     5521 atcatttcat caatgccgaa ggtgaaaatg aagtggaact tgtggagtcg attgataaga
     5581 ggaaagaaat tctcaggaat gttgaagaag tgctaaaggg ttatgcaatt caacgaacca
     5641 aaaaaaataa tcatttctat gatcgcttta tgattcattt gaattatttc ttggattatt
     5701 tagacagatc tagagatgat aaccaatcac ttctggatat ggaagatcat attaaacaat
     5761 cctatccaaa agccttcgag attggttcca agatctatga tgtgattacg caacatacgg
     5821 gtcttgattt gtataaaagt gaacgagttt atctagttct acatatccaa cgtttattgt
     5881 cataaaaatt tatttaaaac tatataagga gaattctatc atgaatagag aagaagtaac
     5941 attgttaggt tttgaaatcg tagcctatgc tggcgatgct cgttcaaaac tattggaagc
     6001 cttgaaggct gctgaagctg gtgattttga aaaagcggac gctctggtag aggaagctgg
     6061 tagctgtatt gcagaggctc accacgcgca aacaagtcta ttgactaagg aagcttctgg
     6121 tgaggactta gcgtatagtg tgaccatgat gcatggccaa gaccacttga tgacaactat
     6181 cttgttaaag gatttgatgc accatttgat cgaactctat aagagaggag ttaaataatg
     6241 aacaaactaa ttgcatttat cgagaaagga aagcctttct ttgagaaact atctcgtaat
     6301 atctatcttc gtgctattcg tgatggtttc attgcaggta tgcctgttat tctcttctca
     6361 agtatcttta tcttgattgc ctttgtacca aactcatggg gctttaaatg gtctgatgaa
     6421 gttgtagcct ttctgatgaa accttatagc tattctatgg gtattctggc tctcttggta
     6481 gctggtacaa cagctaagtc attgactgac tcagtaaacc ggagcatgga aaaaaccaat
     6541 caaatcaact atatgtcaac gctgttagca gcgattgttg gtttgttgat gttggcagct
     6601 gatcctatcg aaagtggtct agctactgga ttcttgggga caaaaggttt gctttcagcc
     6661 ttccttgctg ccttcgttac tgtagccatc tataaggttt gtgttaagaa caacgtcact
     6721 attcgtatgc ctgacgaagt tccaccaaat atctcacaag tctttaaaga tgtgattcca
     6781 ttcactctat cagtggtttc tctttatgct cttgatttac tagctcgtca ttttgttggt
     6841 tctagtgtgg cagaatcaat cggtaaattc ttcgcaccac tcttctcagc agcagacgga
     6901 taccttggta ttaccattat ctttggtgcc tttgccttct tctggtttgt gggtattcat
     6961 ggtccatcta ttgttgaacc tgctatcgca gcgattacct atgcaaatgc tgaagtcaac
     7021 ttgaaccttc tccaacaagg tatgcatgct gataaaatcc ttacttcagg aactcaaatg
     7081 tttatcgtta ctatgggagg tactggtgcg acactggttg ttccattcat gttcatgtgg
     7141 ttaacaaaat caaaacgtaa ccgtgcaatc ggacgtgctt cagtagttcc aactttcttt
     7201 ggtgtaaatg aaccaatctt gtttggtgca ccacttgtat taaatccaat cttcttcatt
     7261 ccatttatct ttgctccaat cgcaaacgta tggattttca aattctttat tgaaactctt
     7321 ggaatgaact cattcactgc taatctacca tggacaactc cagctccact aggtctagtt
     7381 cttggaacta acttccaagt gctatcattc attcttgctg cccttctaat cgtggttgac
     7441 gttgtcattt actatccatt ccttaaggtc tatgatgaac aaattcttga agaagaacgt
     7501 tcaggtaagt ctaatgatga attgaaagaa aaagttgctg caaacttcaa cactgcaaaa
     7561 gcggatgcta ttcttgaaaa agcgggtgta gaagcagcac aaaatacaat cactaaagaa
     7621 acaaatgtcc tcgttctctg tgcaggtgga ggaacaagtg gtctccttgc aaatgctttg
     7681 aataaggcag cagcagaata caatgtccct gtgaaagcag cagcaggcgg ctatggtgct
     7741 caccgtgaaa tgttaccaga gtttgatctt gttatccttg cccctcaagt tgcttcaaac
     7801 tttgaagata tgaaggcaga aacagataag ctcggtatta aactagcgaa aacagaaggc
     7861 gctcaataca tcaaattaac tcgtgatgga aaaggtgctc ttgcattcgt acaagcgcaa
     7921 ttcgattaag gctagagact ctgaaatagt ctcctatcgt tacggaaatc gctatggcga
     7981 atttcctatt attaattcgt cggtaaaaag atatcgtttt tacctcctca tgtcacaatt
     8041 cggtgacttg gtacaagaag tgagatggaa aaggatggct cactgactcc tctcctctca
     8101 cttttacttt atttaaatca agaaataggt gaaaaaaatg acaaaaacac ttccaaaaga
     8161 ctttattttt ggtggcgcaa cagctgccta tcaagcagaa ggtgctacac atactgatgg
     8221 taaaggacca gtagcgtggg ataaatatct tgaagataac tactggtaca ctgcagaacc
     8281 agccagtgat ttttacaatc gatatccagt tgacctcaag ctagcagaag agtatggtgt
     8341 caatggtatt cgaatttcta ttgcttggtc acgtattttc ccgactgatt acggccaagt
     8401 aaatgctaaa ggtgttgagt tttatcataa tttatttgca gagtgtcaca aacgtcatgt
     8461 tgagcctttt gtaactcttc atcactttga cacgccagaa gctctccact caaatggaga
     8521 cttcttaaac cgtgaaaata tcgaacattt tgtagactac gctgccttct gttttgaaga
     8581 atttccagaa gtaaactatt ggacaacctt taatgaaatt ggaccaatcg gtgatggtca
     8641 atatttggtt gggaaattcc ctccaggtat ccagtacgac cttgccaaag tctttcaatc
     8701 acaccacaat atgatggtgt ctcatgcacg cgcggtaaaa ttgtacaaag agaaaggcta
     8761 taaaggggaa attggtgttg ttcacgccct gccaactaaa tatcctctag atcctgaaaa
     8821 tccagcagat gttcgtgcag ctgagttgga agatatcatc cacaataaat tcatcttaga
     8881 cgcaacttat ctaggtcgct attcagctga aaccatggaa ggtgtcaacc atatcttatc
     8941 agtcaatggt ggtagcttgg atcttcgtga agaagatttt acagcattag aagctgcaaa
     9001 agacttgaat gatttcctag gaatcaacta ctatatgagt gactggatgg aagcctttga
     9061 tggagaaact gaaattatcc ataatggtaa aggtgaaaaa ggaagctcta agtatcaaat
     9121 caaaggtgtt ggtcgtcgtg tagctcctga ctatgtacca cgcacggatt gggattggat
     9181 tatctaccct caaggtttgt atgaccaaat catgcgtgtg aagaaagatt atcctaacta
     9241 caagaagatt tacatcactg aaaatggtct cggctataaa gatgagttcg ttgataacac
     9301 tgtttacgat gatggtcgta ttgattacgt gaaacaacac ttggagatct tgtctgatgc
     9361 gattgcagat ggagctaatg taaaaggtta cttcatttgg tcattaatgg atgtcttctc
     9421 atggtcaaac ggttatgaga aacgttatgg tctcttctac gtagattttg aaactcaaga
     9481 acgttatcct aagaaatcag ctcactggta caagaaagta gcggaaactc agattataga
     9541 ctagtagaat tagtcattag atatagaatt ttagtgagtc aaaaagatgt tcaaagattt
     9601 tatccaatct atttatgaaa aagtttatat tataaatttc gaaaaatgct ctcaaatacc
     9661 gtgtttgacg agtgaagaat tgaaaagtct tggaaaatgg tatgtctcga ctggtaaaga
     9721 atggatttgt cattcagatg atgagctgga agaatttaaa aatctatttt taaattttat
     9781 caatcctgaa ggatgggata ctatctcctt tgattcagat tttatgccgt ttcaacaatc
     9841 gtaaccaatt tctcaaaaaa gttaaatctt atatttagta ctctgtaaaa ctcttatcta
     9901 atcacgttgc ttatactcaa tgaaaatcaa agagcaactt taaactagga agcgagtcgc
     9961 agatttctca atgcatagct ttgaggaatt gggcaaaaag tctttgatat agaaaaacgc
    10021 atagtatcag gtgttgaaac acctgatact atgcgtttta ttgtgggaag atttactttt
    10081 tttcttctga aattgagttg ttacccaggc tctttcagtt tattaaggct tgatgacttt
    10141 aatgtgttta gatagcttaa aaaggattga atcacttagt ttagaatctg aaacaatagt
    10201 atcaagattt gatacattat aaaaagtata aaaatcaaac ttattgaact tgctatgatc
    10261 tgcgagtaaa tattttttat tagaattatt taaagcgatg cgttgagcct ctccctcttc
    10321 ctcgctaaaa gtagctagag ctccgttttg aataccatta cagctaacga aagctttaga
    10381 aaattggaga ttagagagat tttgtagggt caatgtacca acaaaagcac ctgtaatatc
    10441 gcgataattt ccacctatta aaatcaaatc tgttaatttt cgttcgctta aaatcagaaa
    10501 aacaggtaga ctgttggtta cgacgcggat attgtcaata ggcaactcac gcgcaaaaaa
    10561 ctctaatgtt gttcctggtc caatgaaaat agtttctctt tcttctacta gactgcctgc
    10621 aaaatgggct atttcttgtt tttctgccgt ttggagggct tgtttttcaa tatttgatcg
    10681 ctcattagtc aaaagggagt tggttcgaag tttttcagct ccaccatgca cacgaatcag
    10741 caaatcttta tcagctaatt cctgtaaata gcgccttgca gtcatatctg aaacggctat
    10801 ttcgtccata atctgtttaa ctgttatggt tcctttacta tttactatct ctaaaatttt
    10861 ggctaatttt tcttgtttga gcatattatc acctcgtttc ctactactat cttaccataa
    10921 acaaactcat cattcaaata caaaaacaac aaaatgaaac aaaaacaaaa atatcgaagt
    10981 ttgttttcaa aactttcgat atttttgttg ggttataact ttgatgtttc tagtttactt
    11041 tttgatgatt gagagtgatg gagaattagt ctaaaccgta gttatagtca tcgtcttgca
    11101 tggcttcaac ttcgccaaga aggtaaccat ttccgacttg agagaagaag tcatggttgg
    11161 aagttcctgt tgaaataccg ttcataacga ttgggttgac atcttcagct gaatctggga
    11221 aaagtggatc ttgtcccatg ttcatgagag ctttattggc attgtagcga aggaaggttt
    11281 taacctcttc agtccaacca acaccgtcat aaagactctc tgtgtagcct tcttcatttt
    11341 cataaagagt atagagtagg tcgtacatcc attctttgag tttttcttgc tcttcttcag
    11401 gcaattcatt gaaaccaagt tggaatttgt aaccaatgta ggttccgtga acagactcgt
    11461 cacgaataat caatttaatg atttctgcaa cgttggcaag tttgttgtta ccgagatagt
    11521 agaggggagt gaagaaacca gagtagaaga ggaaggtttc gaggaagacg ctggcaactt
    11581 tcttttcaag tgggctgccg tttaggtaga tttcgttgac aatctcagcc ttcttttgta
    11641 ggtaaggatt ggtattggtc cattcgaaaa tttcttcaat ctcagcctta gtattcaagg
    11701 tagaaaagat tgatgagtaa gatttagcgt ggacagattc cataaattgg atgttattga
    11761 aaacagcttc ctcatgtggt gtacggatgt ctgcgcgaag ggcttgaacc ccagtttcag
    11821 attgcatagt gtcaagaagg gttaaaccac caaaaacttt tccgaccaag tctttctctt
    11881 tgttagatag ctttctccag tcatccaagt cgtttgataa gggaatacgt gtatcgagcc
    11941 aaaattgctc cgtcagtttt tcccaagttg atttgtcgat gacatcttcg atggcattcc
    12001 agttaatggc tttgtagtaa gtttccattt aaaatctctt tctgtgttta gtattgcgaa
    12061 ctcacaatta tttctacttt accataattc tataggagta tcgcacaaaa agtcggaagc
    12121 ccgactttta aaatgttaca taaattatgt tatgacatag tagatttgat tttatcagtg
    12181 ctgcttaggg aaaaatagtg tttctatgct agaaactaaa tcacacagct ttcacattgg
    12241 ttggcgccga cttctccacc gtcatctgta aaggtacgga cgtagtagat agacttgatt
    12301 cccttgttaa aggcatagtt acgaaggatg gacaaatcac gtgtcgtttg tttattttcc
    12361 ctcttccatt cgtaaaggcc ttttggaatg tcactacgca tgaagagggt gagtgaaagt
    12421 ccttgatcca cgtgttcagt cgcagcagcg taaacatcga tgactttacg catatccata
    12481 tcgtaggcag aagtgtagta aggaatggtt tctgtagaca agccagcagc agggtagtag
    12541 attttaccaa ttttcttctc ttggcgttct tcgatacgtt gcgtaatcgg gtggatagaa
    12601 gcagaaacgt cgttgatata gctgatagaa ccatttggcg ctacagcaag gcgattttgg
    12661 tggtaaagac catcttcttg aaccttgtcg cgaagttcag cccaatcagc aacaccaggg
    12721 ataaagacat ttttgaagag ttctttaaca cggtctgatg ttggaacaaa ttcaccagtt
    12781 acatacttgt caaagtaact tccgttagca tagtctgatt tttcaaagtt gtggaaggta
    12841 ataccacgtt cacgcgcaat attgtttgac tctaccaagg tccagtagtt cataagcata
    12901 aagtagatgc ttgtaaattc aacagactca ggtgaaccat attcaatgag ttgttgggca
    12961 aggtagctgt gcagtcccat ggcaccgaga ccaaaggtgt gggcttggct atttccatgg
    13021 tcaatcgttg gtacagctac gatatgtgaa ctatctgtaa cgaaagtaag ggcacgaacc
    13081 atagcacgga tagaacgacc aaaatcaggt gaagtcatca tgttaaccac gttggttgaa
    13141 cccaggttac atgaaacatc tgttcccatt tgaaggaatt cttgagcatc gttgatcaag
    13201 cttggttctt gaacttgaag aatctcagaa cacaagttac tcatgataat ctttccatca
    13261 acaggatttg cacggttagc cgtatcgatg ttgactacat aaggatagcc agactcttgt
    13321 tgcaatttag agatttcagt ttccaaatcc cgcgccttga tttttgtctt gcgaatattt
    13381 ggatttgcga ccaattcatc gtatttttca gtaatgtcga tgtaattgaa tggcacaccg
    13441 tattcttttt ctacagagta agggctgaag aggtacattt cttcattttt acgagccaat
    13501 tcgtagaatt tatcaggtac tacaacacca agtgatagag tcttgacacg tactttttca
    13561 tcagcgtttt ctttcttagt tgaaaggaaa gcgatgatat ctgggtgaaa gacgttgagg
    13621 tagacaacac cggcaccttg acgttgcccc aattggttgg agtaagagaa gctgtcttca
    13681 aaaagcttca taacaggaac gacacctgaa gcagctcctt catagccttt gataggtgca
    13741 ccagcttcac gaaggttgct gagggtaatt cccacaccac caccaatacg tgaaagttga
    13801 agagctgagt tgatagaacg tccgatagag ttcatatcat ccgtcacttg gattaggaaa
    13861 caagatacca actccccacg gcgagcacgt ccagcattca agaaggaagg agtagcaggt
    13921 tggtagcgtt ggtggatgat ttcattggca atatcgattg caacagcttc attcccatca
    13981 gcgaaataaa gggcgttgaa gaagacacgg tcttccatat tttcaagata gtattcaccg
    14041 tcattagtct ttaaggcata ttgattgtaa aatttataag ctgccatgaa tgacttgaat
    14101 tggaagtttt ggtctttgat aaattgagcc aattcttcca agaactctgg acggtatttc
    14161 ttgataaagg ctgtttcgat gtagttgtgt tcaatgaggt aattgatttt gtctttgatt
    14221 gaatcaaaaa ccatagtgtt tggaactaca ttttctttaa agaaagcatc caaggcttcc
    14281 ttgtctttat gaagcatgat ttgtccatta acaggacggt taatttcgtt attaagacgg
    14341 aagtaagtca cgtcttcaag atgttttaat cccataaaat ttcccttatc taattacaaa
    14401 agaaaggctt ctaagttagc cctaaaagca gttttttctg gatgatgtac taagattatg
    14461 ctaattgctt cagttttcct ggttggaaac ctgaaaagac ttcagttggt gtttggataa
    14521 caggagctgc gctaaaaccg agctctttaa cttgatcgac gtactcaggt tgctcatcaa
    14581 gattgatttc acgataagag acattattac tgtccaagaa acgcttggtc attttacatt
    14641 ggacacaatt gtttttagaa taaacggtta ccattgtgta actcctcttc aaaatttaat
    14701 actatcttag tatatcagaa aataaaattt tgtcaatgat ttgaactaaa tatagtggtg
    14761 ttcttttgtt gtttttatat ataaacacaa tatatagtgt ttgtgttgtg aaatagcaat
    14821 gattatccta taaattgttt ttgaagaaac tatatcctgt gttttgttat ctaggataga
    14881 agattttcag caagttatct gaaaggaaat tgaaggaaaa tccagaaaat gcttgaaaaa
    14941 aatcctagaa gatggtataa tactaaattg taagggttat cacatataac tcaaaaaaag
    15001 aaagaacaaa aggagagtca aactatggct tctaaagatt tccacgtagt ggcagaaaca
    15061 ggtattcacg cacgtccagc aacattgttg gtacaaactg ctagcaaatt tgcttcagat
    15121 atcactcttg agtacaaagg taaatcagtt aaccttaaat caattatggg tgttatgagt
    15181 cttggtgttg gccaaggtgc tgacgtaact atctcagctg aaggtgcaga tgcagatgac
    15241 gctatcgctg caatctcaga aacaatggaa aaagaaggat tggcataagg gaaatgacag
    15301 aaatgcttaa aggaatcgca gcatctgacg gtgttgcagt tgcaaaagca tatctactcg
    15361 ttcagccgga tttgtcattt gagactatta cagtcgaaga tacaaacgca gaagaagctc
    15421 gccttgatgc cgctctacag gcatcacaag acgagctttc tgttattcgc gagaaagcag
    15481 taggtacgct cggtgaagaa gcagctcaag tttttgatgc tcacttaatg gttcttgctg
    15541 acccagaaat gatcagccaa atcaaggaaa ctatccgtgc gaagaaagtg aatgcagaag
    15601 caggtctgaa agaagttaca gatatgttta tcactatctt tgaaggcatg gaagacaacc
    15661 catacatgca agaacgcgca gcggatatcc gcgacgtgac aaaacgtgta ttggcaaacc
    15721 ttcttggtaa aaaattgcca aacccagctt ctatcaatga agaagtgatt gtgattgcgc
    15781 atgacttgac tccttcagat acagctcaat tggacaaaaa ctttgtaaaa gcttttgtaa
    15841 ccaacattgg tggacgtaca agccactcag ctatcatggc acgtacactt gaaattgctg
    15901 ctgtattagg tacaaacaac atcactgaaa tcgttaaaga cggtgacatc cttgctgtta
    15961 acgggatcac tggagaagtg attatcaacc caacagatga acaagcggca gaatttaaag
    16021 cagctggtga agcctatgcg aaacaaaaag ctgaatgggc acttttgaaa gatgctcaaa
    16081 cagtgactgc tgacggtaaa cacttcgagt tggctgccaa tattggtact ccaaaagacg
    16141 ttgaaggtgt taacaacaac ggtgcagaag ctgttggact ttaccgtaca gagttcttgt
    16201 acatggattc tcaagacttc ccaactgaag atgagcagta tgaagcatac aaggctgttc
    16261 ttgaaggaat gaacggtaaa cctgttgtcg ttcgtacaat ggatatcggt ggagataagg
    16321 aacttcctta cttcgatatg cctcacgaaa tgaacccatt ccttggattc cgtgctcttc
    16381 gtatctctat ctctgagact ggagatgcta tgttccgcac acaaatccgt gctcttcttc
    16441 gtgcgtctgt tcacggtcaa ttgcgtatca tgttcccaat ggttgcgctc ttgaaagaat
    16501 tccgtgcagc gaaagcagtc tttgatgaag aaaaagcaaa ccttcttgct gaaggtgttg
    16561 cagttgcgga taacatccaa gttggtatca tgatcgagat tcctgcagca gctatgcttg
    16621 cagaccaatt tgctaaagaa gttgacttct tctcaattgg tacaaacgac ttgatccaat
    16681 atacaatggc agcagaccgt atgaacgaac aagtttcata cctttaccaa ccatacaacc
    16741 catcaatcct acgcttgatt aacaatgtga tcaaagcagc tcacgctgaa ggtaaatggg
    16801 ctggtatgtg tggtgagatg gctggtgacc aacaagctgt tccacttctt gtcggaatgg
    16861 gcttggatga gttctctatg tcagcaacat ctgtacttcg tacacgcagc ttgatgaaga
    16921 aactcgacac agctaagatg gaagagtacg caaaccgtgc ccttacagaa tgctcaacaa
    16981 tggaagaagt tcttgaactt caaaaagaat acgttaattt tgattaatcg aaaaatccct
    17041 gcaactcagt tacagggatt tttttgatat tttaaaaaga attttcaaga aaatctttct
    17101 tatagaaagt ccaaccttga aaaagtagtg gtcagaacaa aaaatactta aatggttcat
    17161 aaaattcttg acaagttgga gatttaggag taaactatta accagttaag taatagagag
    17221 gagtttctgc aatttagaaa tgaattgcaa ctagaaatat caaatagaaa gagagtttcg
    17281 atgaaaatta ataagaaata ccttgttggt tctgcggcag ctttgatttt aagtgtttgt
    17341 tcttacgagt tgggactgta tcaagctaga acggttaagg aaaataatcg tgtttcctat
    17401 atagatggaa aacaagcgac gcaaaaaacg gagaatttga ctcctgatga ggttagcaag
    17461 cgtgaaggaa tcaatgctga gcaaatcgtc atcaagataa cagaccaagg ctatgtgact
    17521 tcacatggcg accactatca ttattacaat gggaaggttc cttatgacgc tatcatcagt
    17581 gaagaattgc tgatgaagga tccaaactac cagctaaaag acgaggatat tatcagtgaa
    17641 atcaagggtg gttatgttat caaggtagat ggaaaatact atgtttacct taaggatgct
    17701 gcccacgcgg ataatgtccg tacaaaagaa gaaatcaatc ggcaaaaaca agaacatagt
    17761 cagcatcgtg aaggagggac ttcagcaaac gatggtgcgg tagcctttgc acgttcacag
    17821 ggacgctaca ccacagatga tgggtatatc ttcaatgcat ctgatatcat tgaggacacg
    17881 ggtgatgctt atatcgttcc tcacggcgac cattaccatt acattcctaa gaatgagtta
    17941 tcagctagcg agttggctgc tgcagaagcc ttcctatctg gtcgggaaaa tctgtcaaat
    18001 ttaagaacct atcgccgaca aaatagcgat aacactccaa gaacaaactg ggtaccttct
    18061 gtaagcaatc caggaactac aaatactaac acaagcaaca acagcaacac taacagtcaa
    18121 gcaagtcaaa gtaatgacat tgatagtctc ttgaaacagc tctacaaact gcctttgagt
    18181 caacgccatg tagaatctga tggccttatt ttcgacccag cgcaaatcac aagtcgaacc
    18241 gccagaggtg tagctgtccc tcatggtaac cattaccact ttatccctta tgaacaaatg
    18301 tctgaattgg aagaacgaat tgctcgtatt attccccttc gttatcgttc aaaccattgg
    18361 gtaccagatt caagaccaga agaaccaagt ccacaacctg caccaaatcc tcaaccagct
    18421 ccaagcaatc caattgatga gaaattggtc aaagaagctg ttcgaaaagt aggcgatggt
    18481 tatgtctttg aggagaatgg agtttctcgt tatatcccag ccaaggatct ttcagcagaa
    18541 acagcagcag gcattgatag caaactggcc aagcaggaaa gtttatctca taagctagga
    18601 gctaagaaaa ctgacctccc atctagtgat
//
LOCUS       DAVHLA010000041        16851 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVHLA010000041 DAVHLA010000000
VERSION     DAVHLA010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16851)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16851)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16851
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.041"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(46..2478)
                     /locus_tag="VVO77_001661"
     CDS             complement(46..2478)
                     /locus_tag="VVO77_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU5693649.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            complement(2480..2938)
                     /locus_tag="VVO77_001662"
     CDS             complement(2480..2938)
                     /locus_tag="VVO77_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEU5693650.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRDLLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQVIQEVDRKGK"
     gene            complement(3061..3786)
                     /locus_tag="VVO77_001663"
     CDS             complement(3061..3786)
                     /locus_tag="VVO77_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5693651.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLE"
     gene            complement(3786..4793)
                     /locus_tag="VVO77_001664"
     CDS             complement(3786..4793)
                     /locus_tag="VVO77_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU5693652.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            complement(4832..5590)
                     /locus_tag="VVO77_001665"
     CDS             complement(4832..5590)
                     /locus_tag="VVO77_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5693653.1"
                     /translation="MRNLRSILRRHISLLGFLGVLLIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRS"
     gene            complement(5553..5843)
                     /locus_tag="VVO77_001666"
     CDS             complement(5553..5843)
                     /locus_tag="VVO77_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEU5693654.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     regulatory      complement(5914..6016)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(6099..7445)
                     /gene="cbpD"
                     /locus_tag="VVO77_001667"
     CDS             complement(6099..7445)
                     /gene="cbpD"
                     /locus_tag="VVO77_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEU5693655.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSGG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDGGSVGNSQSSASTGGTHYFKTKSAIKTEPLASGTVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSGTVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     gene            complement(7534..7800)
                     /locus_tag="VVO77_001668"
     CDS             complement(7534..7800)
                     /locus_tag="VVO77_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693656.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            complement(7802..9154)
                     /gene="dnaB"
                     /locus_tag="VVO77_001669"
     CDS             complement(7802..9154)
                     /gene="dnaB"
                     /locus_tag="VVO77_001669"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEU5693657.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            complement(9197..9649)
                     /gene="rplI"
                     /locus_tag="VVO77_001670"
     CDS             complement(9197..9649)
                     /gene="rplI"
                     /locus_tag="VVO77_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEU5693658.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            complement(9646..11619)
                     /locus_tag="VVO77_001671"
     CDS             complement(9646..11619)
                     /locus_tag="VVO77_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEU5693659.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQIIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGCKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            complement(11755..12303)
                     /gene="raiA"
                     /locus_tag="VVO77_001672"
     CDS             complement(11755..12303)
                     /gene="raiA"
                     /locus_tag="VVO77_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEU5693660.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNIVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            complement(12383..13045)
                     /locus_tag="VVO77_001673"
     CDS             complement(12383..13045)
                     /locus_tag="VVO77_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEU5693661.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            complement(13042..14340)
                     /locus_tag="VVO77_001674"
     CDS             complement(13042..14340)
                     /locus_tag="VVO77_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU5693662.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLSLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            14396..15031
                     /locus_tag="VVO77_001675"
     CDS             14396..15031
                     /locus_tag="VVO77_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEU5693663.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            15316..16236
                     /gene="cysK"
                     /locus_tag="VVO77_001676"
     CDS             15316..16236
                     /gene="cysK"
                     /locus_tag="VVO77_001676"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEU5693664.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLVLAPDNGERYLSTALYEL"
     gene            complement(16433..16831)
                     /locus_tag="VVO77_001677"
     CDS             complement(16433..16831)
                     /locus_tag="VVO77_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU5693665.1"
                     /translation="MKAPIPKAPLAHSFGSASIIAHTIHQKFNLKVPNYRQEEDWAKM
                     GLPITRKEISNWHIKTSQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
BASE COUNT         4971 a         3890 c         2872 g         5118 t
ORIGIN      
        1 tcactccact gtgacttatg gtcagatgct ggtactttta ttcttttatg caatatcaaa
       61 ttttaactgg cctgctttga caccaatctt aagtgtgctg cctgccacta aatctccctt
      121 gagaagaagt tctgccaact tgtcctccac ttctgtttgc agggttctgc gaagtgggcg
      181 agctcccatc tctgggtcat atccttgatt tgctaacaat ttcagagctg aagcttgtaa
      241 tttcaagtca atgccttttt cagccaaact tgccactaaa ggcttgacca taatcttcac
      301 cacttcctgc atatgatcac tagataggct atggaagacc accttctcat caatacggtt
      361 gatgaattcc ggtctataag cttttttcag ttcttcaaac atgcgttttt ccatattttc
      421 ctggtcaaaa cgaatatcct tagccccaaa accaacagtc ttatcatcac gaagggcagt
      481 cgcacctagg ttcgatgtca taatgataat ggtatttgaa aaatcgacct tgcgtccctt
      541 gctatctgtc aagacaccgt catccagaac ctgcaagaga acattaaaga tatctgggtg
      601 agccttctct acctcatcaa agaggagaac ggaatagggt ttattgcgaa ccttctctgt
      661 caactcccca ccttcttcgt aacccacata gcctggagga gctccattta gacggctggc
      721 tgcgaatttc tccatatact cactcatatc aaagcggata agggctgatt cgtcatcaaa
      781 gagaacttct gccaaagcct tggccaactc ggtcttaccg acacctgtgg gtcctaggaa
      841 cataaaggaa ccgatcggac gcttgtgact gcgaattcct gactgattac ggcgaatcgc
      901 acgactaata cttgaaacag cttgatcttg accgataacc cgtttatgga gttctgcttc
      961 aagatttaga tatttcttag cgtcagtctg agtcagcttt tgaactggga ttcctgacaa
     1021 gcgactcaag gtggtcaaaa tatcagactc tgtcaccaag tctttgtaga caggtacttc
     1081 ctcttctttt gcgattagct gggctgcctg tttccacttg ccatccatca gggccttgtc
     1141 agctggactc aaatctgaat cgtctgcttt tacatgcttt gccttatttt gcactgttgc
     1201 tgctgcttcg tccaagaggt cgatagcaga gtctggcaag tgacgactgg ttaaataacg
     1261 atgagccatc ttaaccgctg tttcaaccgc ttcatctgtg atttgtacac ggtgatgttt
     1321 ctcataagtc gccttcaaac cttgtaaaat agtcatacta tctgccacac ttggttcttc
     1381 aatcgtcact ttagcgaaac gacgagaaag tgccgcatct ttttcgatat gtttttgata
     1441 ttcttcctga gtagtggcac caaccgttct caaagttcca cgcgccaagg ctggtttcaa
     1501 gatattggcc gcatccagag tcgaatcaat cccgctacca gaacccatga tggtgtggag
     1561 ttcatcgata aagaggatga cttggccatc ttcttcaata tccttgatga tattattcat
     1621 gcgttcttca aagtcaccac ggaagcgtgt ccctgcaacg acattcatca aatcaagttc
     1681 taacacgcgc atcttagcca tttccgcagg cacgtcacca ctagcaatac gctgggcaag
     1741 accaagggcc agagctgttt tcccgacacc agcatcccca accaagacag ggttgttctt
     1801 agtcttacgg ctcaagattt gaatcatacg tgagatttcc ttgtcccgac cgatgactgg
     1861 ttctaacttg ccagaacgcg cttgctctgt caaatcatgc gtatagtcct cgagaccacc
     1921 actaggagtc tgcggcatgc ccatcatatt ggccatagaa ttttgcttgt cagctactgt
     1981 acgatggcgt tggcgtaaag ccttgagatc ttcacgagtc cagcctgcac gttcttctaa
     2041 atttcgacga agggcagcaa tcttgacctg atctttcttg tcttcataag aaaaaccagc
     2101 cctctccaag atacgagtcg ccaaggcatt gccatcatgc aaaatcgcat agaggacgtg
     2161 ctctgtccct agtaccttag catggaccac tgacgctaca tactctgctt catcaaaaag
     2221 aacctgcaaa cgacgggaga acggcaattc cgtaaaggtt tcatcctggc tatagtccgt
     2281 ttcagtcagt tccaaagcca cctcttctaa acggtccatc tcatacggat aatcatttaa
     2341 agttgcccct gctacactat aactgtgatt agacatggca atcaacaagt gccacgactc
     2401 tagataacga gctccaaaat gtccagcaac catgtaggca ctttcgatac attcattcaa
     2461 tgcttttgaa tagttcatct tacttccctt ttctatctac ctcttgtatg acctgacgta
     2521 gcatgtttgc tcgaacaact ggagcttctt ctcctaaaac gcgatccaaa gctactgatt
     2581 ctagcaaatt catctcctgc ttggtcatca attcctgctc aaccaaaagc tggagaatat
     2641 cctcataaat ttcttgactg actcgctcac caatcgagta aagcagatcc cggagcattt
     2701 catgatgact agaaaactca atccgtccta tacgaatgta gcctccgcca ccacgcttac
     2761 tttcaaccaa gtagcctcta ctttccgtaa agcgtgtctt gatcacgtag ttaatctgac
     2821 taggaacaac ctgaaaggta tctgccaact gactccgttg caactccacg ataccagatt
     2881 gatctaaaat cgccttgatg taggcctcaa tatgatccga tgtattttta aatctcataa
     2941 caaacccacc tctctcttta aaccttgacc ttgtttgact attataccga aattttctca
     3001 tttttaaaag aaaaagggcg ctggtaaagg ataatcttca ccaactccct atttttctac
     3061 ttattctaag cctaattctg ccaagatttg acgtttgtag gcaatctttt ggacttcctt
     3121 gtcctcatct tcagaccaat ctagtttaat ttctgaaaca atctgcccag ggcgattttt
     3181 caagatatag atgcggtcgc tgagattgag ggcctcctca atactatgcg tgatgatcag
     3241 agttgttagc tgcaactgtt tgtgaatctc aagataccaa gcgtggagtt ccatctttgt
     3301 catctcatcc aaggcgctaa aggcctcatc taagagaaag agcttgtgcc caaaaaggta
     3361 ggtccggagt aaggctacac gctggcgcat cccaccgcta agttcatgag gatacttgtc
     3421 tcttacagct gtcagctgga aggtcgcaag aattttatcc gctcgggaaa tagcttctgc
     3481 cttatccacc ttttgaatca agaggggcag aatgatattt ccaagcaccg tcttgtgctc
     3541 caagagcaga tccttttgca acatataact cacgcgcccc ttgggatttt cttcaccatc
     3601 aaggacaatt ctccctgact gaacttctaa aatcccagcg attagattaa agagggtggt
     3661 ctttccaaca ccacttgggc ctaggatgga aaccacttcg cctgaagtca cctgtagatt
     3721 gatatcctct aaaatcctct cctgaccata ggcataactg acgtgctcta gtctaatttc
     3781 tgtcattatt tcacaaattc gttggtgaag cctttgtctg tcaagtcttc tttaaggata
     3841 ccattttctt tatcccattt gtagaaagca ttccagcgag ctgcgtcaaa ttgaccccat
     3901 ttttccttgt cgcttgcgta ttcttttgac aagtattttt gagattcgat gacaaagtca
     3961 cgtttttcct tgagttcagg tgcattcttg atgagaatat ctgcagcttc ttctggatgt
     4021 tccatggcat attggtagcc ttttttgatg gcttggatga ctttgcgagc ttcttctttg
     4081 ttatctttca gatagtcgtt gtttgcgatg ataactggtg aatagtagtc aaactccttg
     4141 acatagtctt tcaagtacat gaagttagca tctacacctt gagatttagc aaggatacca
     4201 tcccaaccgt agtaaatcca agcagtatca aagacgccat tggcaatcgg tgtgattgag
     4261 tttgagtcgt tatttggtac tttttcaacc ttctcaaagt ctccaccttg agattctacc
     4321 aaggttttca acatagcaag ttcagttggg tcattccatg tcccatattt cttaccaacc
     4381 aagtcttttg gactgcttac attatcagat ttacgagaga tgattcctga tgtattgtgt
     4441 tcaacaatag ctgcaacggc agtgattcct gctccttttt ccaatttctt agccatgtag
     4501 tcttggaaat acactgcaaa tggtgccttt ccgttgataa ccaagtcaga agaactttct
     4561 tctggtggca atttcaaatc aacatccact ccagcttctt tgaaataacc tttttccttg
     4621 gcaacataaa gccctgtgtg gttggtattt ggtgtccagt ctaggataaa gtcaaccttc
     4681 ttaagttctg cctctttgtt gtctttagaa gcagttcctt gaccacaggc cacaagcaca
     4741 acagctacaa gagctgttac aagcgttaaa aacactttcc atgttttctt cattttgatt
     4801 tcctcttttc tttttcagaa acattctaat tctacgaacg tttccattta atcacatatt
     4861 tttcactgat atcgaccagc ttcataccca aaagactgat aatcgacacc agaataataa
     4921 tggcaaacat ggtatcatac tgaaacaatt ttttagactg aatcatataa acaccaagac
     4981 cttcaaaacc tcccaaccac tcagatacca cagttgtgat aaaggcgtag gagacactga
     5041 ccctcagacc tgcataaaag taaggcaggc taactgggat tttaaaatgc cacaggattt
     5101 gccaaggctt ggcccgcatc agactaaaca aggtcagcat atccttgtcg caatgcctaa
     5161 aaccgtccaa aatactaacg atgatgggaa aggttgtcgt taagataatc aagacaatct
     5221 tgggcaaaat cccataacct agccacaaga ccaggatagg agctatggca atggtcggaa
     5281 tggtctgaat gaccaccatc atagggtaaa tcaggtcatt gagccaagtc aaactatcca
     5341 tgagcacagc cataagacag gcaatcaaaa ctcccaaaat cagccccagt aaagccactc
     5401 tcaaggtcgc ccagctatgg tgccagagaa attctctgtc acgaacaaag ggctggagaa
     5461 tttcaagagg tgtcggcagg ataaacttgg ggagaagttt aagaaaacct gctaactgcc
     5521 agattaacaa gactccgaga aagcccaata gactaatgtg tcgtctcagt atacttctca
     5581 agtttctcat caatacttaa aatctctcct acatttattt tgacattggc aaagacattg
     5641 tctgcctcct gccctgccac ttccagcgct tcttttagaa tgcgcataag ctcatcaaac
     5701 tccccttcca agaccgtttc aaatggtgtc actaccatcg tcacttcttg agtttgcaga
     5761 taagcaatga cctgatcaat aacagctatc cgatcaatcc cctgtgctag gggtaaaact
     5821 tgcaaggcaa tgcttgcttt cataagaacc tcctcttctc gttttccttt ttaaaaaaag
     5881 aaaaaccttt accatacatg gaaaaggtgc aaaattagac taagtatcgt tccctccgct
     5941 ggcattaccc agatcaggtg cggtcgaagt ttaacacttc ctctcagact gtacacagac
     6001 tcccatatat tatatgtata tatgatagcg caaaataaga aaaatgtcaa ggaaactgct
     6061 tacagaaaag agcaggaaat ttctcctact ccaattttct atactcgttc tccatcactg
     6121 tttactctgt agccatccac cgtcgtatta acagctaagg cgcctgaaga gtaagaataa
     6181 taccacttac cagagacctg gtaccagcct gttttcattg cccctgaact acccagataa
     6241 taccacgagc cattctcctt taaccatcct gtctgcattt caccagataa tttcaaataa
     6301 taccagctag aaccgtcttt cagccatcct gttgatttag aaccatttga tttgaaatga
     6361 taccaactac catttatttt cttccaaccg acagttgaac tattattgga tccatagcta
     6421 gagatatttc ctgattgatt ctgataattt tgtgaagaag tcactccctc tagctgtata
     6481 tagcgacgac ttccattata ggcagtataa ctcaaccact tgtagccgtc tttttcaagt
     6541 atctgatcat aatgaacctt ctctccagga taatagtaat caatcacagt tccgctaact
     6601 aggggttcag ttttgatagc agacttggtc ttaaaataat gagttccacc tgttgaagaa
     6661 agaacagaat tacctagagg atttttattc acagcctcca attgaacata acgatagctt
     6721 ccattatagg cagtataact caaccactta tagccgtctt tttcaagtat ctgatcataa
     6781 tgaaccttct ccccaggata atagtaatca atcacagttc cgctagctag gggttcagtt
     6841 ttaatagcag acttggtctt aaaataatga gttccgcctg ttgaagctga ggattgacta
     6901 ttcccaacac tgccgccatc caaatcttta aaatgaataa atcctgtcat cgtgtttgct
     6961 tttataactc gtttattata ggattctgta taaccatagt tatattcctc aatctcaatc
     7021 tgatctccca ttacatttga cacccaggca acatgaccat aagttcctgc agtagaccaa
     7081 gtaatggaac caatcgtcgg tgtattatct acacgataac cttcccgacg agcacgatgt
     7141 ccccattcat tcgcatttcc ataagctgcc ggaatttcaa aaccattgac attactcaaa
     7201 cgaaaggcta caaaagaagt acactgacga gaatacatgc gccactgatc aatctcctgg
     7261 ctcccatttt tataataagc aggataatca tccccacgcg caatcgatcc atttcctccg
     7321 gaataggcat agacactatc accagctgct agcatcaatc ctactactaa aaaaggaaca
     7381 agctttttaa ctgacatctt caagtaataa cttgtccctc ttgctataaa cggtaaaatt
     7441 ttcattcttc ctccttgaaa aataatataa agcgatgatt gccttcacct aaattattcg
     7501 gagaaaaaag aaaaagtgag aaaatttctc actttagtca agataatgaa tcaaattctt
     7561 ttctgtaaga atatctgagt aagtaaagga ttcaacgtaa acattaactt gtttatctcc
     7621 ttccacatcc ccaaactcca caataaatag agatggataa acttcaatta gcttacccaa
     7681 tctatttttt tggcgcttac gaccattctc caaagtcatt tctacgactt gtccctcatg
     7741 tgccttgatt tcttctttga tttttttcat cttggctaca tctgtaaatg catctgacat
     7801 cttatgcctc cctctttgag atacttgaaa atttattgta ttctttttgg aaaatcaatt
     7861 ccactgttcc acgagctcca ctacggtttt tctcgataat aacttccacc ttattatttg
     7921 ggataccctc ctcttcttca ccaccacgtt catagtagtc atcgcgatag agaaaagcta
     7981 cgatatcagc gtcctgctca atagacccag attcacgaat atcagacaag accggtctct
     8041 tgtcctgacg ttgttctaca ccacgagaaa gctgactcag agcgattact ggaaccttca
     8101 attccttggc tagtattttc aactgacgag aaatttcaga aacttcttgt tgacgatttt
     8161 ctcgaccagt tcccgtgata agttgcaaat agtctatcaa aatcaaacca agatttccag
     8221 tttcttgagc caatttacga gaacgagaac gaatctctgt aatccgaata cctggcgtat
     8281 catcgatata gatactggcg ttagctagat taccctgagc aatagtatat ttttgccact
     8341 cctcatctgt caattgccct gtacggatag aatgtgactc cactaagcct tctgcagcta
     8401 acatacgatc taccaagctt tccgcaccca tttcgagtga aaaaatagca accgttttgt
     8461 ccaacttagt cccaatattc tgagcgatat tcaaggcaaa tgctgtctta ccaactgctg
     8521 gacgagctgc taagataatc aactcctcct catgaagtcc tgttgtcata tgatccaaat
     8581 cacgataacc tgtcgcaata cctgtaatat cggtcgtttg ttgcgagcga gcttccagat
     8641 ttccaaagtt gagattcaac acatctcgaa tgttcttaaa cccgcttcga tttgcatttt
     8701 cactgacatc aatcaaccct ttttctgcct gagcaataat ttcatcagct ggttgtgacg
     8761 cttcgtaagc ttggttgaca gactctgtca acttggcaat taaacgacgt agcattgctt
     8821 tttctgcaac aatcttagca taatactccg cattagcaga agttggcaca gaattaacaa
     8881 tctcaaccaa gtaagacaag ccaccaatat tctgtaaatc accttgatta tcaaggatag
     8941 tacgaaccgt tgttgcatct atggcatcac cacgatcgga taaatcgacc atggcttgga
     9001 aaatcaaacg atgggcatac ttaaaaaagt cccgagactc aatgtattct cgcacaaaaa
     9061 caagtttact ctcatcaata aagatagccc ctaaaacgga ttgctcagct aagatatctt
     9121 gaggttgtac tcgtaactct tctacttctg ccatcagact tcccttcttt tacaatcttg
     9181 tcaagaaagt gtaaacttat ccttctttca cacgaagatt gattacactt gtgatatctt
     9241 gatagatttt cactggcaca tcaatcaaac caaccgctcg aatcggagct tgtacttgaa
     9301 tatgacgttt atcaatctta attccaaatt gcttttgcaa ttcttctgca atcttcttat
     9361 tggtaataga accaaaggta cgaccatctg gaccaacttt ttcaacaaat tctacaacag
     9421 tttcttctgc ttcaagttgt gctttaattg cttttccttc tgcaatcatc tcagcgtgag
     9481 ctttttcttc cgatttttgt ttaccacgaa gttcacctac agcttgagca gtcgcttctt
     9541 tggctagatt ctttttgata agaaagtttt gcgcataccc tgttggtact tccttaattt
     9601 cgcctttttt accttttcct ttaacatctg ctaaaaagat tactttcatt cttctttctc
     9661 cttttccttt atttcattta atacaatttc tgtcagtttt tcacctgctt ctgacaaggt
     9721 tacatcttta atttgagctg ctgccaaatt aaagtggcct ccaccgccta actcttccat
     9781 aatccgttgt acattcagtt tactacgact tcgagctgag atagagataa atccttgtgt
     9841 attcttcgca agaacaaaac tcgcttcaat acctgacatg gctaacatgg catctgctgc
     9901 cttactaata acaactgtat catagcattt cgtgtcctta gcctctgcta ttagtacatc
     9961 tgaacctaat ttacacccct gtaaaataag ttcattgacc tcacgatatt cttcaaaatc
    10021 tgtcgcagcg atttcctgga tagcaatact atcacttccg cgcgttctga gatagctagc
    10081 aacatcaaat gtccgactag ttactcgcga ggtgaaattt ttagtatcca acatcatacc
    10141 agccatcaaa acacttgctt gcatacgact caaacgattt ttcttagaat tctggaactg
    10201 aatcaattcc gttaccaact cactggcact acttgcacca ctttcgatat aagtaataac
    10261 cgcattatct ggaaaatcct gatcccttct atggtggtca ataacaatga tttgggtaaa
    10321 taaatcataa aattcttttg ataatgttaa ggctgtcttt gaatggtcta caagaatcaa
    10381 caaagaacga ttggtcacca tccccattgc atccttaaca gacaacaact tcgtaactcc
    10441 ttctttttct atgaatgaaa cagctcgttc aatatctgga gacatttgtt cttcatcata
    10501 aagagcatag ctattttcaa tcacattgct ggcgaacaac tgcataccta cagcagagcc
    10561 caaagcatcc atgtctaaat ttttgtgacc gactacaaaa acctgatcta cactccgaat
    10621 cttatctgaa atagctgtca tcatagcgcg cgtacgagtc cgtgtacgct tgattgaagc
    10681 agcagaccca ccaccaaaat aaactggatt tttcgtttcg tcgttttcct taacaaccac
    10741 ctggtcgcca ccacgtactt cagccaagtt caaattgagc aaagcaactt tccctatctc
    10801 atcatgattt ccatcgccat aagaaaatcc catacttaag gtcaagggca actgtctctg
    10861 tttcgactct tctctgaaag catcaataac agaaaattta tcattcatca agccctcaag
    10921 caccgtgtag tcagtaaata gataaaatcg atccatactt acccgacgag aaaacatcat
    10981 gtatttttct gaaaactctg atataaaatt agctacaaaa ctattgattt gactaatatc
    11041 tgactcagaa gttgcatcct ccaaatcatc ataattatcc acagagacaa tcccaatcac
    11101 tggtcgactt gttaccaatt catctgttat ggcttgttcc ctggatacat ctacaaaata
    11161 caaaacaccg gaagaagcat ccatatgaac agcataacgc ttctcaccaa gcttggcata
    11221 agtagacgga tttcctactg aagccttgat aatcgtttga acagcttcta aatcaaaatc
    11281 accatcttcc ttggtcaaaa tcaattcagc atagggatta aaccactcaa cctctccaga
    11341 agataaattc aatttcataa cacctacagg catctgttcc aatagagctg tcaaactttc
    11401 ttccgcttgg tggtttacat actgtatctg ttctacatca ctccttgtat aatgcactct
    11461 cagtttctta aataaaaaaa catagcctcc tacaaaaaga aacaaaatta aaaccgtcaa
    11521 cagattatta ttaacaaaaa taatgaaagt ggataagact ccaaacgcaa tcaatcctac
    11581 tagaatagga aaaattggac ttacataaaa ttttttcatt caaaacctct tggcacccat
    11641 tataccataa tacccctcaa aaagcgactt tttaaaagtg taatcagtaa ttctatcaat
    11701 tataagaaaa aggtagttta caattcagta aacctacctt tacacatatt gaaattaaga
    11761 ttctttaacc tctaacaaac caatttcgcc atcctcacga cgataaatca cattggttgt
    11821 ctgatcttca acatccacat agataaagaa atcatgcccc aataaatcca tttgtagaat
    11881 tgcttcttcc aaatccattg gttttaaatc aatttgtttt gaacgaacaa ctttagactg
    11941 gacaatattt gaatcttcca ccaaagcatc tgtaaataat tgaccagttg ctaccttatt
    12001 tttattttta cgctcgattt ttgttttatt tttacgaatc tgacgttcaa ttttatcagt
    12061 tacaaggtca attgaaccat acatatcttg agatacatct tctgcgcgga gagtaataga
    12121 tccaagcgga atcgttactt ccactttagc cgttttttca cgataaactt ttaagttaat
    12181 tcgggcatcc aactcttgtt ctggttggaa gtacttttcg atcttttcga gtttagaaac
    12241 tacataatca cgaattgctt ctgttacttc taggttttca ccacggatac tatatttaat
    12301 catatgagta ccttctttct aaacattttt gtttttatga ttttattata acgctttcat
    12361 tctatttttg caaatttttt cctcatctta caagggaaaa tgtttttaca tccttagcac
    12421 cagcttcttc caacagtttc ttaacacgat ttatagttgc tcctgtagta tagatatcat
    12481 ctataagtag gattttttta ggaatagtga ctccactttt aataaagaaa ggaagttctg
    12541 tccccaagcg ctctgaacga tttttagaag aactggctct ctcttctctt ttctctaata
    12601 aatccagata ctcaaagcct gctgcctcta ccaagccctc aacctgatta aatcctctgt
    12661 tagcatatct atcaggactt aggggaatta caacaaattg atactctttg tactttttca
    12721 actcctcact taaaaatgaa gcgaaaactt ttcttaacag gaagtctcca tcaaacttat
    12781 accgactgaa aaaatccttc atagcttgat tgtaagtaaa aatcgctcta tgactgactt
    12841 caactccttc tttacaccaa agttgacagt cttgacactt tgttgacaac tctgttttca
    12901 tacaatttgg acagttctct tccccaattc tttcaaaagt agaatcacag tctgaacaaa
    12961 gacaagagtc atcattcctc agaagtaaga gactactaaa agttaaaaca gtcttcatag
    13021 tctgcccaca taacaagcac ttcatagacc agcctcctta ttcatcatct gaatttcctt
    13081 aatcgccttc ttgattgaag catttaaccc atcatggaag aaaagcaaat ctcctgtcgg
    13141 tctatccatg cttcgtccaa ctcgtccacc aatctgaatc aaactagact tggtaaacaa
    13201 acgatgattg gcctctacta cgaaaacatc cacacaaggg aaggtaactc cacgctccaa
    13261 gattgtcgta ctgataagta ttgtcagttc tccatctcga aaagcttgta cttgctctaa
    13321 tcgatcctct gttacagaag atacaaagcc aattttctca tttggaaatt gctcctgtaa
    13381 gatttcttct aactgctccc ctttcttaat ttctgaagca aaaatgagta acggataagc
    13441 tgtctttctc tgcttctcaa tataggactt taactttggt gacaaacgat tcttgtctaa
    13501 gtagcgatta aaatccgata accaaattgg ttttggaata atcaacggat ttccatgaaa
    13561 ccgtctcggt aaactcagtc tttttagttc tcctaaacgg acctttttat ctaactcatt
    13621 ggtcgaagtc gctgttaaaa agattctcaa tccattctcc tttacactat tcttgacagc
    13681 gtggtaaagc gtgggattat caacataagg aaaagcatct acttcatcca ctatcagcaa
    13741 atcaaaagct tgataaaact tcaataactg atgggttgtt gcaacaacta gtggtgttcg
    13801 aaaataaggt tccgattctc catgtagcaa agctatcccg caagaaaaat cctgttgcag
    13861 gcgcttgtac agctccaaac aaacatctat gcgaggacta gccaaacaca ctgcaccacc
    13921 cgcattgatc actttagcca ctacttgata aatcatttct gtctttccag ctcctgttac
    13981 cgcatgaact aaggttggct tttgcttgtc tactgcttga agcagtccct ctgacacctt
    14041 ctcttgaaaa ggagttaatt ggccgcgcca tttgagaaca tcttgcttcg gaaaatcctc
    14101 ctgcggaaaa tagtataaag tttgatcact tctgactcgc ttcatcagca agcactctcg
    14161 acaatagtaa gcaccgatgg gcaaatacca ttcttctaga atagtactat tacaacgttg
    14221 acagaaaagt ttccccttct cctttctcat tgctggaagt ttctccgcca actgacgttc
    14281 ttcttctgtt aattcattct cagtaaataa acgaccgaga taatctaaat ttactttcat
    14341 acttctttat tcgtaaaaac tagcacttta gattattttt tagtacaatt aaatcatgga
    14401 atttaggaca attaaagagg acggccaagt ccaagaagaa atcaaaaaat ctcgctttat
    14461 ctgccatgcc aagcgtgttt atagcgaaga agaggctcgt gacttcatta ctgccatcaa
    14521 aaaagaacac tacaaagcga cacataactg ctctgccttt attattggag aacgtagtga
    14581 aattaaacgt acaagtgatg atggtgagcc tagtggtact gctggtgttc ccatgcttgg
    14641 ggtactagaa aatcacaatc tcaccaatgt ctgtgtggtc gtgacacgct actttggtgg
    14701 tattaaacta ggcgctggag gactaattcg tgcttacgcc ggcagtgtcg ccttagctgt
    14761 caaagaaatt ggtattattg aaataaaaga acaggctggc attgctattc aaatgtctta
    14821 tgctcagtac caagagtaca gtaacttcct taaagaacat gatctcatgg agctggatac
    14881 aaactttaca gatcaagtcg atacgatgat ttatgttgat aaagaagaaa aagaaactat
    14941 taaagctgca cttgtggagt tttttaatgg aaaagtcact ttaactgacc aaggtttacg
    15001 agaggttgaa gttcctgtaa acttagtgta aacaatgaat aatacagcgt ttcgttgaca
    15061 ttctcacaac tactttagcg agcaaaataa aaagatgcgt accaaaatat actagaaaat
    15121 gaagcaattc aaacgaaacc tgatatcgtt ttccttcaca cctatttact agaattaact
    15181 gaacgcaatc acttgaaaat taatgacttt gatctatgat atatagaaat cctatcgctt
    15241 cgataggatt tctatatttt acaaatggta tggatagcgt tatactaaag atatcttata
    15301 caaagaggta ttcatatgtc tatttataac aacattactg aattaatcgg tcaaacaccg
    15361 attgttaaac ttaacaacat cgtgccagaa ggtgctgcag acgtctatat aaagcttgaa
    15421 gcatttaatc ctggttcatc tgtaaaagac cgtattgccc ttagcatgat tgaaaaagct
    15481 gaacaagatg gtattctgaa acctggttct actattgttg aagcaacaag tggaaacact
    15541 ggtattggac tttcatgggt aggtgctgct aaagggtata aagtcgtcat cgttatgcct
    15601 gaaactatga gtgtagaacg acgtaaaatt atccaagctt atggtgctga actcgtccta
    15661 actcctggta gcgagggaat gaaaggtgct attgctaagg ctcaagaaat cgctgctgaa
    15721 cgtgatggtt tccttcctct tcaatttgac aatccagcta atccagaagt acacgaaaga
    15781 acaacaggag ctgagatact agctgctttc ggtaaagatg gattagatgc ctttgttgct
    15841 ggagtaggta ccggtggaac gatttctggt gtttctcatg cactcaaatc agaaaattct
    15901 aacattcaag tttttgcagt agaagcagat gaatctgcta ttctatctgg tgaaaaacct
    15961 ggtcctcaca aaattcaagg tatctcagct ggatttattc ctgatacact tgatactaaa
    16021 gcctatgatg gtatcgttcg tgtaacatca gatgacgctc ttgcactcgg acgtgaaatt
    16081 ggtggaaaag aaggcttcct tgtagggatt tcctcagctg cagctatcta cggagccatc
    16141 gaggttgcca aaaaattagg tacaggtaaa aaagtccttg tcctagcacc agataacggt
    16201 gaacgttatc tctctacagc actttatgaa ttgtaaccgt ccaataacga agtatattga
    16261 aaaatctcca gactagagaa ctcacggata gttcctaatc tggagatttc ttatttgcac
    16321 ttttcttgta caactttagt ccatggtaaa taagcctcta aaacctcttt gtttacgaga
    16381 gtttccacgt ttggaagaca ttctagaaga taggatagat atttctcact atttataatg
    16441 gattgaaata agatatgaac aaatcgatta ggacatgatg gtaaagcgta atcccttgtt
    16501 tctcagcttt cccagacaaa aaagtccaat agtaagtcag ctgactatca ctctctagca
    16561 ccctataaga agtttcatcc gcatgaagta agggctgagt caatagtctc tctcgcaaga
    16621 ggttatagag gggctccaaa tagtattgac tcgtcttgat atgccaatta gagatttcct
    16681 tgcgtgtgat tggtaaaccc atcttagccc aatcttcttc ttggcgataa ttgggtacct
    16741 tcagattaaa cttctgatgg atggtgtgag cgataataga agctgagcca aagctatgcg
    16801 ctaaaggggc tttaggaata ggagctttca caagcttatc cagatgatta t
//
LOCUS       DAVHLA010000042        16061 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVHLA010000042 DAVHLA010000000
VERSION     DAVHLA010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16061)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16061)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16061
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.042"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(90..1331)
                     /locus_tag="VVO77_001678"
     CDS             complement(90..1331)
                     /locus_tag="VVO77_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEU5693666.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            1434..2543
                     /locus_tag="VVO77_001679"
     CDS             1434..2543
                     /locus_tag="VVO77_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEU5693667.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            3189..3536
                     /gene="ssrA"
                     /locus_tag="VVO77_001680"
     tmRNA           3189..3536
                     /gene="ssrA"
                     /locus_tag="VVO77_001680"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(3719..3806)
                     /locus_tag="VVO77_001681"
     tRNA            complement(3719..3806)
                     /locus_tag="VVO77_001681"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3770..3772),aa:Ser,seq:gga)
     gene            3968..4708
                     /locus_tag="VVO77_001682"
     CDS             3968..4708
                     /locus_tag="VVO77_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU5693668.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPAVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            4705..5616
                     /gene="pfkB"
                     /locus_tag="VVO77_001683"
     CDS             4705..5616
                     /gene="pfkB"
                     /locus_tag="VVO77_001683"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEU5693669.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVESVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAELIKETYGKVEVEKR"
     gene            5613..7565
                     /locus_tag="VVO77_001684"
     CDS             5613..7565
                     /locus_tag="VVO77_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU5693670.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTDHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGAFYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALSVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YVAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            7729..9954
                     /locus_tag="VVO77_001685"
     CDS             7729..9954
                     /locus_tag="VVO77_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEU5693671.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGSSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKAQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(9999..10427)
                     /locus_tag="VVO77_001686"
     CDS             complement(9999..10427)
                     /locus_tag="VVO77_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693672.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITASITIMN
                     ALDNNKNIKKEPTTSQTTTIVKEIQKESPKENTSPTKETNTSQEKTQQEETPKSSVKE
                     EKKEDQKTATQDSSTPASSKPATENEKQSNAPTSENKSNQ"
     gene            10565..11707
                     /locus_tag="VVO77_001687"
     CDS             10565..11707
                     /locus_tag="VVO77_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU5693673.1"
                     /translation="MIYFDNSATTKPYPEALETYMQVASKILGNPSSLHSLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWVIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKSQGFEVDFAPVDKKGLVDVEALAGLIRPDTILVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDGVQALTKIPTEKYLTERVDFATFSSHKFHGVRGVGFVYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     NYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAKSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            11716..12930
                     /gene="thiI"
                     /locus_tag="VVO77_001688"
     CDS             11716..12930
                     /gene="thiI"
                     /locus_tag="VVO77_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEU5693674.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYTQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKE
                     GMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAY
                     LSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            13065..13870
                     /locus_tag="VVO77_001689"
                     /pseudo
     CDS             13065..13870
                     /locus_tag="VVO77_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
     gene            13892..14631
                     /locus_tag="VVO77_001690"
                     /pseudo
     CDS             13892..14631
                     /locus_tag="VVO77_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            14644..15810
                     /locus_tag="VVO77_001691"
     CDS             14644..15810
                     /locus_tag="VVO77_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEU5693675.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMDQMIADFGQRQE"
BASE COUNT         4668 a         2997 c         3520 g         4876 t
ORIGIN      
        1 tctttgattt tgagtattag atttactcaa aatcaaggat tttgaagatg aacttgtatc
       61 aaaaaatcgc ggtttaaaat cgcgattttt tataatttct cgttaacaaa gcggacaaac
      121 tgattccacc aaacttttaa gaagaaggct ttttcaattt tcttgtctgc taccatttcg
      181 aaactagggc gctctgtggt gatgtaacct tgaccaatca agtccttgtc ttcataagtc
      241 aaatggccaa ccactgttcc agcttcaagt ggtgctggga ttgctttgga atcaggtgtg
      301 aattgaacag attgggaaga ttgattccca acacgttcga ttagatagat atcctctgga
      361 gccactgcag ttactgtatc ttcttttcca tcttgtacag gggctttgct atcttgatag
      421 gcatcgcctt gttgaacgat tttgcgaagt gtaaatgtag aagaaatata atccattagg
      481 gaagatgtag ctgtaaatcg agcgtaagga ttattgtctt gatgatctgc atttaaaaca
      541 actgtgatga ctctcatgcc tttttcgaca gtagtaccaa caaaagactc tccagcctta
      601 tctgttgttc ctgtttttag cccatcaaaa ccaccacggt aagcaggcat accttctaac
      661 atgtagttgg ttgaagtgat tgtcatccca gcaaaagtag aagatggttt tttggtgatt
      721 tctaagactt gtgggtattt tttgatgagg ttgcgagcaa cgatagcgac atcataagca
      781 ctaagcttat tttcctcatc ttttttagaa cctgggtaaa tgttatcccc tagagtttca
      841 ttgttaagac ctgtcgtatt gacaacagtg gcatcctgaa ttccccattc caagagtttt
      901 gcccgcatca tatcgacgaa atctttttct gagccagcaa ttttctcagc tagggcaata
      961 gcggcgctgt tggcactaga taccagagtt gcttcaagca actcttcgac agtataatta
     1021 cgggcctcca taggaatatt actggcttca gaatttgtcg tcaattgata aggataatca
     1081 gaaatatcta caggagtgga gagggtaata cttccgtttt ccaaagcttc atagaccaga
     1141 taaacagtaa tcaattttgt tatggaagca atttcgacag gttgcgttgc atccttctca
     1201 tagagaattt taccagtatt tgcctcaaca gcaatcgcat gtttagcggc aatggtaaaa
     1261 tcttgagcaa cagcagtaga agcaccccct aaaagagaga cagttaacaa agttaaaaat
     1321 atttttttca tagtagtctt attctatcat aaagaaaaaa aatattcttg ctttaataat
     1381 tcatctgtta agctttttga aaatatggta aaataaagtg agggaggtaa ctcatgtttc
     1441 gtagaaataa attatttttt tggaccacag aaattttact cttaaccatc atcttttacc
     1501 tatggagaca gatggggtct ttgattaacc cttttgttag cgtgcttaat acaattatga
     1561 ttccattttt attagggggc tttctttatt atttgacaaa ccctattgtt actttcttaa
     1621 ataaagtctg taaactcaat cgtttgcttg gtattttaat taccttgtgt actttggtct
     1681 ggggaatggt cataggtgtt gtctatctct tacctatttt gattaatcag ttatctagtt
     1741 tgattatatc tagtcaaact atttatagtc gagtacaaga cttaatcata gacttatcta
     1801 attatcctgc gctccagaat ttggatgtag aagctacaat tcagcagtta aacttatcct
     1861 atgttgatat tcttcaaaat atcctaaata gcgtatcaaa tagtgtgggg agcgtcttgt
     1921 cagctcttat cagtactgtt ttgattttga ttatgactcc agtttttttg gtttatttct
     1981 tattagatgg acataaattc ttgcccatgc ttgaaagaac gattctaaag agggatcgct
     2041 tgcatattgc aggcttatta aagaatttaa atgcgacgat tgctcgctat attagtggag
     2101 tttcgattga cgcaatcatt ataggttgtt tggcttatat tggctatagt attattggtt
     2161 taaaatatgc tttagttttt gccatttttt ctggtgtagc caatttaatt ccttatgtgg
     2221 ggccaagtat tggtttgatt cctatgatca tcgcaaatat attcactgat ccccatagac
     2281 tgctgattgc agtgatttat atgcttgttg ttcagcaggt agatggcaat atcttatatc
     2341 ctcgaattgt aggaagtgtt atgaaggttc atccaatcac gattttagtt ttacttttgt
     2401 tgtcaagcaa tatctatggt gtagttggaa tgattgtcgc agtgccaacc tattctatct
     2461 tgaaagaaat ttctaagttc ttatcccgtt tgtatgaaaa tcataaaata atgaaagaac
     2521 gagaaagaga attagctaag taaaagtcag gagaaccctg atttttcttt actggaagtg
     2581 gcctttagat tagaagactg aaaataagtt aaagtcttaa actaattttc acagctaaga
     2641 atagtagaag ttaatctgat aaaaatcgaa aaaaccagtg gaattccgtg tcagggtaag
     2701 ttccactggt tttcatagtc tattaaagtt cgaatgaaac ctatttatag tatattgaaa
     2761 ctagaatagt acacctctaa ttctaaaaca ttgttagaaa tcgatttgac tgtcctgatc
     2821 tattcgtcct attcttattt cattttacta tattttggtg caataagtga aaagtagtcc
     2881 gaataatata aggattgatt ttatagtttt taaactcaaa tgaattaaaa taaagagagt
     2941 acgaaaattc tcatctgaaa gtattttaga ataattttct tcgtgaattt cttcaaaaca
     3001 gatagcttca tcttaggtat gtgttaattg gatttcgtaa gctctattta caatcgtaaa
     3061 gttatgcact gagaaagttg tagttagtct tccagtttgc taaatttctc gaatagtatc
     3121 ttttttaggt atgtgatttc tttttgcatt tttgagttag ataaggtata atggttttat
     3181 tgtcttttgg ggtcgttacg gattcgacag gcattatgag gcatattttg cgactcgtgt
     3241 ggcgacgtaa acgctcagtt aaatataact gcaaaaaata acacttctta cgctctagct
     3301 gcctaaaaac cagcaggcgt gacccgattt ggattgctcg tgttcaatga caggtcttat
     3361 tattagcgag atacgattaa gccttgtcta gcggcttgat aagagattga tagactcgca
     3421 gtttctagac ttgagttatg tgtcgagggg ctgttaaaat aatacataac ctatggttgt
     3481 agacaaatat gttggcaggt gtttggacgt gggttcgact cccaccggct ccattattcc
     3541 tttgcattct tttgcattcc ttggtaaaac gttgttaaat caacgttttt tatttttatc
     3601 tttggtattc ctttgcattc ttttgctaaa aagggagtca caaacagacc ctattttaaa
     3661 aaaaggatag aaaaaaggat acaacatttg tcgcatccta aaaataatct tttttccacg
     3721 gaagacatgg gattcgaacc cacgcacgct attacacgcc taccgcgttt ccaacacggc
     3781 ctcttaagcc tcttgagtaa tcttccaata cttactcaaa tagtctacca taaaggctct
     3841 tatcttgcaa taaaaattct agaaatatga aaaatgatag attttgaaag aaaatgataa
     3901 aaaatgcttg acttcgaaag aaagtatgat agaatgaata gtgtaaacga taacaggagg
     3961 tgattcagtg ttaaaaacag aacgtaaaca actaatttta gaggagttaa atcaacatca
     4021 tgtagtttct ctagaaaaat tagttagttt gctagaaacg tcagaatcaa cggttcgaag
     4081 agacttggat gagttggaag cggaaaacaa gcttcgtcgt gtgcatggtg gagcagaact
     4141 cccccactcc ttacaggaag aagaaaccat tcaagaaaaa tctgtcaaaa accttcaaga
     4201 aaagaagttg ctggctcaga aagcagcctc tctcattaaa gaaaaagatg tcatctttat
     4261 cgatgctgga acaacaactg cttttttgat tcatgaattg gtcaataaga atgttacagt
     4321 tgtgaccaac tccattcacc atgccgctca gttggttgaa aagcagattc cagctgtcat
     4381 ggttggagga aacgtcaaga cggcgacaga tgctagtatc gggggcgttg ctcttaacca
     4441 gattaaccaa ttgcactttg accgtgcctt tatcggaatg aatggtgttg acgatggcta
     4501 ttatacgact cctgatatgg aggagggagc tgtgaaaaga gctattttgg agaatgccaa
     4561 gcagacctac gtcttggtgg attcgtcaaa aattggacaa acttgctttg ccaaggtagc
     4621 accactcaaa cgcgctatcg ttatcactag tcaagggcat gagctcttgc aggttattaa
     4681 ggagaaaacg gaggtaatag aagtatgatt tatacagtca cactcaatcc atccattgac
     4741 tatatcgttc gtttggacca agtcaaagtt ggtagtgtaa atcgtatgga cagtgatgat
     4801 aagtttgctg gtgggaaagg aatcaatgtc agccgtgtct tgaaacgttt gaatatacca
     4861 aatacagcga cgggatttat cggtggcttt actggtaaat ttatcacaga tactttagca
     4921 gaggaagaaa tcgagacacg ttttgtccag gtggcagaag atactcgtat caatgttaaa
     4981 atcaaagcag accaagaaac agaaatcaac ggaacgggtc caactgttga atcggttcag
     5041 ctagaagaat tgaaagctat tttatctagt ctgacagcag aagatacagt tgtctttgca
     5101 ggttcaagtg ctaaaaatct aggcaatgtt atctataagg atttgatttc cttgacgcgc
     5161 cagactggtg cgcaagtggt ctgtgacttt gaaggacaga ccttaattga tagtttggac
     5221 taccagcctc ttcttgtaaa accaaacaat catgaacttg gagcgatttt tggggttaaa
     5281 ctcgaaagtt tagatgaaat tgagaaatac gctcgtgagt tactggctaa gggtgctcaa
     5341 aatgttatta tctctatggc tggggacggt gctcttcttg tcacatctga gggagcttac
     5401 tttgctaaac caatcaaagg aacagtcaaa aattcagttg gggctggtga ttctatggtt
     5461 gctggattca caggtgaatt tgtcaaatca aaagacgcag tagaagcctt caaatgggga
     5521 gtggcttgcg gaacggcaac taccttctca gatgacttgg caacggcaga acttattaaa
     5581 gaaacatatg gaaaagttga ggtagaaaaa cgatgaaaat tcaagaccta ttgagaaaag
     5641 atgtcatgtt gctagatttg caggcaactg aaaaaacagc tgtcatcgac gagatgatta
     5701 aaaatttgac agaccacggt tatgtaacag attttgaaac atttaaagaa ggaattttgg
     5761 cgcgtgaagc tttgacttct actggtttgg gtgatggaat cgcaatgcct cacagcaaaa
     5821 acgctgctgt caaagaagcg acagttctat ttgctaagtc aaataagggt gttgactacg
     5881 agagcttgga tggacaagca actgacctct tcttcatgat tgcagctcca gaaggtgcca
     5941 atgatactca cttggcagcc ttggcagaat tgtctcaata cttgatgaaa gacggttttg
     6001 cagacaaact tcgtcaagca acatctgcag accaagttat cgaacttttt gaccaagctt
     6061 cagaaaaaac tgaggaactt gttcaagcac ctgctaatga ctctggtgac tttatcgtag
     6121 ctgttacagc ttgtacaaca ggtattgccc acacttacat ggcccaagaa gcccttcaaa
     6181 aagtagctgc tgaaatgggg gttggtatca aggtcgaaac caacggtgct agcggtgttg
     6241 gaaatcaact aactgcagaa gatatccgta aggctaaagc tattatcatt gcagcagaca
     6301 aggccgttga aatggatcga tttgatggaa aaccattgat caatcgtcca gttgctgacg
     6361 gtatccgtaa gacagaagag ctaattaact tggctctttc aggagatact gaagtctacc
     6421 gtgccgctaa tggtgcaaaa gctgcaacag cctctaacga aaaacaaagc cttggtggtg
     6481 ccttctacaa acacttgatg agtggtgtat ctcaaatgtt accattcgtt atcggtggtg
     6541 gtatcatgat tgcccttgcc ttcttgattg acggtgcttt gagtgttcca aatgaaaacc
     6601 ttggcaatct tggttcttac catgagttag cttctatgtt catgaaaatt ggtggagctg
     6661 cctttggttt gatgcttcca gtctttgcgg gttatgttgc ctactctatt gctgaaaaac
     6721 caggtttggt agcaggtttc gtggctggtg ctattgccaa agaaggtttt gcctttggta
     6781 aaattcctta tgtcgcaggt ggtgaagcaa cttcaactct tgcaggtgtc tcatctggtt
     6841 tcctaggtgc ccttgttggt ggatttatcg caggtgcctt ggttcttgcc atcaagaaat
     6901 acgttaaagt tcctcgttca ctcgaaggtg ctaaatcaat ccttctattg ccacttcttg
     6961 gaacaatctt gacaggattt gttatgctag ctgtgaatat cccaatggct gcaatcaaca
     7021 ctgctatgaa tgacttccta ggtggtcttg gaggaggttc agctgtcctt cttggtatcg
     7081 tccttggtgg aatgatggct gttgacatgg gtggaccagt taataaagca gcttatgtct
     7141 ttggtacagg tacgcttgca gcaactgttt cttcaggtgg ttctgtagcc atggcagcag
     7201 ttatggctgg aggaatggtg ccaccacttg caatctttgt cgcaactctt cttttcaaag
     7261 ataaatttac taaggaagaa cgtaactctg gtttgacaaa catcatcatg ggcttgtcat
     7321 ttatcactga gggagcgatt ccatttggtg ccgctgaccc agctcgtgcg attccaagct
     7381 tcatccttgg ttcagcagta gcaggtggac tcgttggtct tactggtatc aaactcatgg
     7441 cgccacacgg aggaatcttc gttatcgccc ttacttcaaa tgctctcctt tacctcgttt
     7501 ctgtcttggt aggagcaatc gtaagtggtg tggtttatgg ttacctacgc aaaccacaag
     7561 cataaaaaat agaaaaatga aaagattgga ccgtttggtg cagtcttttt ctcttcccga
     7621 aatgcctgtg aaatatggta taatagaaga atggcaaaca agaatacaag tacaacaaga
     7681 cggagaccgt ctaaagcaga actggaaaga aaagaagcga ttcaacgaat gttgatttcg
     7741 ttaggaattg cgattttatt gattttcgca gccttcaaat taggggctgc aggtataacc
     7801 ctttataatt taattcgctt gctagtgggt agcctagctt atctggcgat attcggccta
     7861 ttaatctatc tcttcttttt caagtggata cgaaaacagg aaggactctt atctggtttt
     7921 ttcaccatat ttgctggctt actcttgatt tttgaggcct acttggtttg gaaatatggt
     7981 ttggacaagt ccgttctaaa agggaccatg gctcaggttg tgacagatct gactggtttt
     8041 cgaacgacta gctttgctgg agggggcttg atcggggtcg ctctttatat tccaacagcc
     8101 tttctctttt caaatatcgg aacttacttt attggttcta tcttgatttt agtgggttct
     8161 ctcctagtca gcccttggtc tgtttacgat attgctgaat ttttcagtag aggctttgcc
     8221 aaatggtggg aagggcacga gcgtcgaaaa gaggaacgct ttgtcaaaca agaagaaaaa
     8281 gctcgccaaa aggctgagaa agaggctaga ttagaacaag aagagactga aaaagcctta
     8341 ctcgatttgc ctcctgttga tatggaaacg ggtgaaattc tgacagagga agctgttcaa
     8401 aatcttccac ctattccaga agaaaagtgg gtggaaccag aaatcatcct gcctcaagct
     8461 gaacttaaat tccctgaaca ggaagatgac tcagatgacg aagatgttca ggtcgatttt
     8521 tcagccaaag aagcccttga atacaaactt ccaagcttac aactctttgc accagataaa
     8581 ccaaaagatc agtctaaaga gaagaaaatt gtcagagaaa atatcaaaat cttagaagca
     8641 acctttgcta gctttggtat taaggtaaca gttgaacggg ccgaaattgg gtcatcagtg
     8701 accaagtatg aagtcaagcc ggctgttggt gtaagggtca accgcatttc caatctatca
     8761 gatgacctcg ctctagcctt ggctgccaaa gatgtccgga ttgaagcacc aatccctggg
     8821 aaatccctaa tcggaattga agtgcccaac tccgatattg ccactgtatc tttccgagaa
     8881 ctatgggaac aatcgcaaac gaaagcagaa aatttcttgg aaattccttt agggaaggct
     8941 gttaatggaa ccgcaagagc ttttgacctt tctaaaatgc cccacttgct agttgcaggt
     9001 tcaacgggtt cagggaagtc agtagcagtt aacggcatta ttgctagcat tctcatgaag
     9061 gcgagaccag atcaagttaa atttatgatg gtcgatccca agatggttga gttatctgtt
     9121 tacaatgata ttccccacct cttgattcca gtcgtgacca atccacgtaa agccagcaag
     9181 gctctgcaaa aggttgtgga tgaaatggaa aaccgttatg aactctttgc caaggtggga
     9241 gttcggaata ttgcaggttt taatgccaag gtagaagagt tcaattccca gtctgagtac
     9301 aagcaaattc cgctaccatt cattgtcgtg attgtggatg agttggctga cctcatgatg
     9361 gtggccagca aggaagtgga agatgctatc atccgtcttg ggcagaaggc gcgtgctgca
     9421 ggtatccaca tgattcttgc aactcagcgt ccatctgttg atgtcatctc tggtttgatt
     9481 aaggccaatg ttccatctcg tgtagcattt gcggtttcat caggaacaga ctcccgtacg
     9541 attttggatg aaaatggagc agaaaaactt cttggtcgag gagacatgct ctttaaaccg
     9601 attgatgaaa atcatccagt tcgtctccaa ggctccttta tctcggatga cgatgttgag
     9661 cgcattgtga acttcatcaa ggctcaggca gatgcagact acgatgagag ttttgatcca
     9721 ggtgaggttt ctgaaaatga aggagaattt tcggatggag atgctggtgg tgatccgctt
     9781 tttgaagaag ctaagtcttt ggttatcgaa acacagaaag ccagtgcgtc tatgattcag
     9841 cgtcgtttat cagttggatt taaccgtgcg acccgtctca tggaagaact ggagatagca
     9901 ggtgtcatcg gtccagctga aggtaccaaa cctcgaaaag tgttacaaca ataaaaaaat
     9961 agcttctttc cgagtttgga gggaagctat tttagtggct attgattgct tttattttct
    10021 gaagttggcg cattggactg tttttcgttt tcagtagcag gtttacttga agcaggagta
    10081 gaagagtcct gagttgctgt tttctgatct tcttttttct cttccttgac gctagatttt
    10141 ggtgtttcct cttgctgtgt tttttcttga ctagtgttag tctctttagt tggactggtg
    10201 ttttccttag gggattcctt ttggatttct ttgacaatgg ttgtcgtctg gcttgtcgta
    10261 ggttcttttt taatattttt gttattatcc aaggcgttca taatcgtgat acttgcggta
    10321 atcaagccaa ggatactagc gattgtagca acggtttttt gaaagactgt aaagcctttt
    10381 ttgatgtgtt ctgtttttgg ttttgaagtt ctacgatagt tagacataca ttctctcctt
    10441 tgattatgat ttattatact ctgtttcttt aaaaaaatct taaaaaaaga gaaattgccc
    10501 tttcttgtcg caagctccgt ttcatgatac aatagaggaa gtgattttag aaagcgtgag
    10561 aaacatgatt tactttgata attcagcgac gaccaagcct tatcctgaag cccttgaaac
    10621 ctatatgcag gtcgcttcaa aaattttagg aaacccatct agtctccata gtttgggaga
    10681 ccaagcaaca cgaatcttag atgcttctcg ccaacagatt gcagatttaa tcggtaagaa
    10741 aagcgatgaa atcttcttta cctctggtgg aacagaaggg gataactggg ttatcaaggg
    10801 tgtggccttt gaaaaagctc agtttggcaa gcacatcatt gtttcagcca ttgaacatcc
    10861 agcagtcaaa gagtcagccc tctggttgaa aagtcaagga tttgaagtgg attttgctcc
    10921 agttgataag aaaggcttgg tcgatgttga ggcgttagca ggtttgatac ggcctgatac
    10981 aatcctcgtt tctatcatgg ctgtgaacaa tgaaatcggc tctatccaac ctattgaggc
    11041 tatttcagaa ttcttggcag acaagccgac tatttccttc cacgttgatg gggttcaggc
    11101 gcttaccaag attccgactg aaaagtatct gacagaacga gtggattttg cgactttctc
    11161 tagtcacaag ttccacgggg ttcgaggtgt tggctttgtc tatatcaaat ctggcaagaa
    11221 gattacacct cttcttacag gtggtggcca ggagcgagat tatcgttcga caactgaaaa
    11281 tgtggcaggg attgcagcga cagccaaggc cctccgtttg tctatggaaa agctagatat
    11341 ctttaggagc aagactgggc agatgaaggc agtgattcgc caagctcttc tgaactatcc
    11401 ggatattttt gtcttttcag atgaggaaga ctttgcacct catattctga cttttggaat
    11461 caaaggtgtt cgaggtgaag tcatcgttca cgcctttgaa gactatgata ttttcatctc
    11521 aacaacctca gcttgttcat ctaaggcagg aaaaccagcc ggtaccttga ttgccatggg
    11581 agtggacaaa gataaggcca agtcagctgt gcgtcttagc ctagacttgg aaaatgatat
    11641 gagtcaggtc gagcagtttt tgaccaagtt aaaattgatt tacaatcaaa ctagaaaagt
    11701 aagataggag cattcatgca gtattcagaa attatgattc gctacggaga gttgtcaacc
    11761 aagggtaaaa accgtatgcg tttcatcaat aaacttcgta ataatatttc ggacgttttg
    11821 tctatctata cccaagttaa ggtaacagca gatcgcgacc gtgcccacgc ttacctcaat
    11881 ggagctgatt acacagcagt tgcagaatct ctcaaacaag tttttggaat tcaaaacttt
    11941 tctcctgttt ataaggttga aaaatctgta gaagttttga agtcttctgt ccaagagatt
    12001 atgcgggaca tctacaagga aggtatgacc tttaagattt ctagcaagcg tagcgaccac
    12061 aactttgaac ttgatagtcg tgaactcaac caaacacttg gaggggctgt attcgaagcc
    12121 attccaaatg tgcaagttca aatgaaaagt cctgacatca atcttcaggt ggagattcgt
    12181 gaagaagcag cctatctttc ttatgaaacc attcgtgggg ctggtggttt gccagttgga
    12241 acttcaggta aagggatgct catgttgtca ggagggattg actcacctgt agcaggttat
    12301 cttgctctta agcgtggggt ggatatcgag gcagttcact ttgctagtcc accatatact
    12361 agtcctggtg ccctcaagaa agcgcaggac ttgacccgta aattgaccaa gtttggcgga
    12421 aatatccagt ttatagaggt gcctttcaca gagattcaag aggaaatcaa agccaaagcg
    12481 ccagaagctt atttgatgac tctaactcgt cgctttatga tgcggattac tgaccgtatt
    12541 cgtgaggtac gaaatggttt ggttatcatc aatggggaaa gtctaggtca agtagccagc
    12601 caaacccttg aaagtatgaa ggctatcaat gctgttacca acactcccat cattcgtcct
    12661 gtggttacca tggacaagtt ggaaatcatt gacatcgccc aggaaatcga tacctttgac
    12721 atttcaatcc aaccgtttga agactgttgt accatttttg caccagatcg tccaaaaaca
    12781 aatcctaaaa ttaagaatgc ggagcagtac gaagcgcgta tggatgttga aggcttggtt
    12841 gagcgagcag tggctggaat catgattact gaaatcacac ctcaagccga aaaagatgaa
    12901 gttgatgact tgattgataa tctactctaa ttcagaaaat ccaaaagaat agcgaaaatc
    12961 agtaaaaaaa gttagttttt tctctaaaaa caggtaaaaa actaactttt tttattttta
    13021 tgatataatg atataaaatt ttgaatatag agagttttct gacaatgaat caatcctact
    13081 tttatctaaa aatgaaagaa cacaaactca aggttcctta tacaggtaag gagcgccgtg
    13141 tacgtattct tcttcctaaa gattatgaga aagatacaga ccgttcctat cctgttgtat
    13201 actttcatga cgggcaaaat gtttttaata gcaaagagtc tttcattgga cattcatgga
    13261 agattatccc agctatcaaa cgaaatccgg atatcagtcg catgattgtc gttgctattg
    13321 acaatgatgg tatggggcgg atgaatgagt atgcggcttg gaagttccaa gaatctccta
    13381 tcccagggca gcagtttggt ggtaagggtg tggagtatgc tgagtttgtc atggaggtgg
    13441 tcaagccttt tatcgatgag acctatcgta caaaagcaga ctgccagcat acggctatga
    13501 ttggttcctc actaggaggc aatattaccc agtttatcgg tttggaatac caagaccaaa
    13561 ttggttgctt gggcgttttt tcatctgcaa actggctcca ccaagaagcc tttaaccgct
    13621 atatcgagtg ccagaaacta tcgcctgacc agcgcatctt catctatgta ggaacagaag
    13681 aagcagatga tacagacaag accttgatgg atggcaatat caaacaagcc tatatcgact
    13741 cgtcgctttg ctattaccat gatttgatag cagggggagt acatctggat aatcttgtgc
    13801 catccatagt gaaatccctt ggtcagaaaa tctaccagat tgtctgagat tttttgcaga
    13861 aaaatggtaa gttaagaaag gaaaaaacga aatgcatatt gaacatctta gccactggag
    13921 tggtcatcct aaccgtgaaa tgtaccttaa ccgttatgga catggtggga ttccagttgt
    13981 ggtctttgct tcatcaggtg gtagtcacaa cgaatactat gattttggca tgattgatgc
    14041 ctgtgcttcc tttatcgagg aaggccgtgt ccagttcttt accctatcta gtgtggatag
    14101 tgagagctgg ttggctactt ggaaaaatgc tcatgaccaa gcggaaatgc accgtgccta
    14161 cgaacgttat gtgattgagg aggccattct tttatcaagc acaagacagg ttggtttgat
    14221 ggcatgatga cgacaggttg ctctatggga gcctatcatg cacttaattt cttcctccag
    14281 catccagatg tctttaccaa agtgattgct ctcagtggtg tttacgacgc acgtttcttt
    14341 gtcggtgatt actacaacga tgatgctatt taccaaaact cgccagtaga ttatatttgg
    14401 aaccaaaacg acggctggtt tattgaccgt taccgtcagg cagagattgt gctgtgtacg
    14461 gggcttggag cctgggaaca agatggttta ccatcctttt acaagctcaa agaagccttt
    14521 gaccagaaac aaattccagc ctggtttgct gaatggggac atgatgtcgc ccacgactgg
    14581 gaatggtggc gtaaacaaat gccttatttc ctcggtaatc tctatttata aaaggagtta
    14641 cctatgaatt accttgttat ttctccctac tatccacaaa actttcaaca gtttaccatc
    14701 gaactagcta ataaaggcat cacagtcttg ggaattggtc aagagtctta cgagcaattg
    14761 gatgagccct tgcgcaatag cttgaccgag tattttcgtg ttgataatct tgagaacata
    14821 gatgaagtca aacgtgcagt tgcttttctc ttttataaac atggtccaat tgaccgcatc
    14881 gagtctcaca atgaatactg gcttgagcta gacgcaacac tcagagaaca attcaatgtt
    14941 tttggtgcca aaccagagga tctcaaaaag acgaaatata agtctgaaat gaagaaactt
    15001 ttcaaaaaag caggtgttcc tgtggtacct ggagctgtta tcaagacgga agcagatgtt
    15061 gatcaagcag tgaaagaaat cggtcttcca atgattgcca aacctgataa tggagtggga
    15121 gcagccgcaa cctttaaact tgagacagaa gacgatatca atcacttcaa gcaagaatgg
    15181 gaccattcaa ccctttattt ctttgaaaaa tttgtcactt ccagcgaaat ctgtaccttt
    15241 gacgggctcg tggacaagga tggaaagatt gtcttctcaa caacctttga ctacgcctat
    15301 acaccgcttg acctcatgat ttataagatg gacaattctt attatgtgct caaggatatg
    15361 gatcctaaac tgcgcaagta tggggaagca attgtcaaag aatttggtat gaaagaacgg
    15421 tttttccata ttgagttctt ccgtgagggg gacgattata ttaccatcga gtacaataac
    15481 cgccctgcag gtggttttac cattgatgtt tataactttg ctcattcctt ggacctttat
    15541 cgtggctatg cagctattgt cgcaggagag gagttcccgg cgtcagactt tgaaactcag
    15601 tattgtttgg ctacttctcg ccgtgcaaat gctcactatg tttattcaga agaggatttg
    15661 cttgccaaat atagccagca gttcaaggtt aaaaaagtca tgccagctgc cttcgcggaa
    15721 cttcaaggag attacctgta tatgctgaca actccgagtc gacaagaaat ggatcagatg
    15781 attgctgatt tcggacaacg tcaagaataa gaactatcgg attaaggaaa ttcactccct
    15841 taatcctttt gttttgtctg gtaaaaaata agagcatcct aacaaggtag ctatcataaa
    15901 acttgttcga taactatttg aagcaggatt aggtggctag aaattgaatt ttaacatttc
    15961 aattgagtca tagtattgtg ttttcgtatc cttaaatcag ctaaaaggat ccatgacgac
    16021 acctatacga tatagttttc aggataccaa acaagtctat t
//
LOCUS       DAVHLA010000043        15725 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVHLA010000043 DAVHLA010000000
VERSION     DAVHLA010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15725)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15725)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15725
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.043"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     regulatory      73..161
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            376..1044
                     /locus_tag="VVO77_001692"
     CDS             376..1044
                     /locus_tag="VVO77_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEU5693676.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKVFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVDKNREDLTELQQRWNQAVALELAFFDI
                     GYNV"
     gene            1287..2069
                     /gene="thiM"
                     /locus_tag="VVO77_001693"
     CDS             1287..2069
                     /gene="thiM"
                     /locus_tag="VVO77_001693"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEU5693677.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            2071..2700
                     /locus_tag="VVO77_001694"
     CDS             2071..2700
                     /locus_tag="VVO77_001694"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEU5693678.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIKNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNVDGVSIISAISYAKNIEKTVREMSEQ"
     regulatory      2909..2997
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            3258..3818
                     /locus_tag="VVO77_001695"
     CDS             3258..3818
                     /locus_tag="VVO77_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU5693679.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     gene            3819..5204
                     /locus_tag="VVO77_001696"
     CDS             3819..5204
                     /locus_tag="VVO77_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5693680.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQVI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILLQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVAASPELFHMNRVTGELGNRSLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRITWKGSVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            5206..5856
                     /locus_tag="VVO77_001697"
     CDS             5206..5856
                     /locus_tag="VVO77_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEU5693681.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFLPSIALNLLVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            5867..6625
                     /gene="tenA"
                     /locus_tag="VVO77_001698"
     CDS             5867..6625
                     /gene="tenA"
                     /locus_tag="VVO77_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000397218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEU5693682.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKEMEISDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEEWKHEKAPTTSSQINHFIYDDCP"
     gene            6564..7088
                     /gene="thiW"
                     /locus_tag="VVO77_001699"
     CDS             6564..7088
                     /gene="thiW"
                     /locus_tag="VVO77_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEU5693683.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            7088..7891
                     /locus_tag="VVO77_001700"
     CDS             7088..7891
                     /locus_tag="VVO77_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEU5693684.1"
                     /translation="MQEFTNPFPIGSSSLIHCITNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRIAASYAAQVCLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSENQVAVLGNGCAELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            7884..8516
                     /locus_tag="VVO77_001701"
     CDS             7884..8516
                     /locus_tag="VVO77_001701"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEU5693685.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKIETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPI
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(8725..9516)
                     /gene="thiD"
                     /locus_tag="VVO77_001702"
     CDS             complement(8725..9516)
                     /gene="thiD"
                     /locus_tag="VVO77_001702"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEU5693686.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSNARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     regulatory      complement(9600..9698)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            9882..10277
                     /locus_tag="VVO77_001703"
     CDS             9882..10277
                     /locus_tag="VVO77_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEU5693687.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVDKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     gene            10288..10659
                     /locus_tag="VVO77_001704"
     CDS             10288..10659
                     /locus_tag="VVO77_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEU5693688.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKRSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            10669..12912
                     /locus_tag="VVO77_001705"
     CDS             10669..12912
                     /locus_tag="VVO77_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEU5693689.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKEIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDVIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQSLHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNILGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            13119..14894
                     /gene="spxB"
                     /locus_tag="VVO77_001706"
     CDS             13119..14894
                     /gene="spxB"
                     /locus_tag="VVO77_001706"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEU5693690.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            15005..15352
                     /locus_tag="VVO77_001707"
     CDS             15005..15352
                     /locus_tag="VVO77_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU5693691.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(15469..>15725)
                     /locus_tag="VVO77_001708"
     CDS             complement(15469..>15725)
                     /locus_tag="VVO77_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU5693692.1"
                     /translation="IWHKSSTLKIPTNIGFAFIPPYTPEMNPIEQVWKEIRKRGFKNK
                     AFRTLEDVMNQLQDVIQGLEKEVIKSIVNRRWTRMLFESR"
BASE COUNT         4622 a         2870 c         3471 g         4762 t
ORIGIN      
        1 taaagatatt tttcggtcaa atatcttgct agggctttca ttttttgcta tactggttca
       61 gtaattaaat aatagagaca tttggggtgc tttaggctga gataataccc attgaacctg
      121 atacagttaa gactggcgaa gggaaatgtg aaacgttttt tcgtatggcg aaatgaacga
      181 tctaatcttg taagtcaact ctaattcttg attgtaattg gagttttttg tttatataaa
      241 ctggataggc ttgtttagtt agctctctgc aaatgctctc gatgtgcttt aaaaggatca
      301 agtggaatta cgattttgct tgatatttct tggtgtttta ttaattacta acaagtaaag
      361 agaggagaag taaatatgga aacacaagac tatgcatttc agccaggttt gactgttgga
      421 gaattattaa aaagcagtca gaaggattgg caggctgcaa tcaatcatcg ttttgttaag
      481 gaactttttg cggggacaat tgagaataag gtcttaaagg actatctgat tcaagattat
      541 cacttctttg atgccttctt atccatgctg ggtgcctgcg tagctcacgc agataaactt
      601 gaatccaagc ttcgttttgc caagcaacta ggctttcttg aagcagatga agatggttat
      661 ttccaaaagg tttttaaaga gttaaaagta gcagagaatg actatctaga agtgactttg
      721 caccctgtaa caaaagcctt tcaggatcta atgtattcgg cggtggcttc atcagactat
      781 gcccatcttt tggtcatgct ggtcattgca gaaggtctct atttagactg gggttctaaa
      841 gatttggctt tacctgaagt ctatattcat tcggaatgga tcaatctcca cagaggtcct
      901 ttctttgcag agtgggttca atttctggtt gacgaactca atcgtgtcga taaaaatcga
      961 gaagatttga cagaacttca gcaacgctgg aatcaagcag tcgctttaga attagctttt
     1021 tttgatattg gttacaatgt ctagagaagg ctcatgatat ttacaaattt gatgaggtaa
     1081 gactcttcga aaatctcttc aaaccacgtc agttctatcc acaacctcaa aacagtgttt
     1141 tgagcaacct gcggttagcc tcctagtttg ctctttgatt ttcattgagt ataaatcatt
     1201 caatgtaaat gaaaaaaatt cttaacgaaa gatagaaata aatcgaaatc agtagatcgt
     1261 ataaagtgaa aaggaaggat ttcaatatga caagtttaaa attattaaaa gaaaaagcac
     1321 cattggtcat ttgtataacc aatgatgtag taaaaaattt cacagcaaat ggattagtag
     1381 cactgggcgc ctcaccagcc atgagtgagt ttccagcaga tttagaggat ttgttaaagt
     1441 atgctggtgg tttattaata aacataggaa cattgacaga tgaaaattgg aaattatacc
     1501 aagctgctct gaaaattgca gagaaatata atgtcccagc agttttagat cctgtagcct
     1561 gtggagcagg agaatataga aaaaaagtag cagatgatct aatcaacaat tataaactag
     1621 cagcgattag aggaaatgct ggcgagattg cctctttagt aggaatagat gtggcatcta
     1681 aaggagtaga tagtgcgggc gtagataata ttgacgaaat tgctctagca gcaaatgaga
     1741 agttcaatat tccaatagta gtaacaggtg aagtggatgc cattgctgtt aatggagaag
     1801 tggtaacgat tcataatggt agtgctatga tgccgaaagt cattgggaca ggatgcttat
     1861 taggggcagt ggtagcaagc tttatcggac tagaaaaagg tcaagaattg aaatcattag
     1921 aaacagcaat gttggtttac aatatcgctg gagaaatggc agaaaaacgt ccaaatggac
     1981 atcttcctgg gacatttaaa gttgaattta taaatgcctt atacgagatt acagatgaag
     2041 atgtaaagga attcaaaaga gtgaagtaag atgtttcata aagaattact aaaactatat
     2101 tttatttgtg gaacgactac ttgccaagga aaaaatctat atacagtcgt tgaggaagcc
     2161 ttaaaaggtg gtataacctt atttcaattt cgagaaaaag gtgagggtgc tttagaaggc
     2221 ttagaaaaac ttgagctagc tatccaaatt aaagaacttt gtaaaaaata caatgtgccg
     2281 tttatcgtta atgatgatat cgatttggca atggaaattg acgctgatgg cgtacatgta
     2341 ggtcaagatg atattggtgt tgatgaaatt agaaaattga tgccagataa aataattggt
     2401 ctttctataa aaaacgagga agaatttcaa caatcaaaag ttgaatatgt agattatgtt
     2461 ggtgttggtc ctgtatttga tacccagtca aaggatgatg ctggtggtgc tataggttat
     2521 gaaggtcttg aattgatgag aaaactattg ccacaaatgc ctttagttgc aattggtggg
     2581 atacagacga aacatattaa agacattata aagaccaatg ttgacggcgt ttcaatcatt
     2641 tcggcaatat cgtatgcaaa aaatatagaa aaaactgttc gggaaatgag tgagcaatag
     2701 atatctatcc ttggattcta agtaagtagg attttccttt tttaaaaagc tatgtctaga
     2761 ttcagcttga atggttaatt catcaaacag gtcatttgtt ttttgcaaaa gaaagatctg
     2821 ctgtctttgt gagtgcaagg ctgtatttcc agttcaattt cttgaactag tataaaatgt
     2881 gtgttataat aatcacataa ttaaataata aaggcatttg gggtgcttta ggctgagatg
     2941 atacccattg aacctgatac agttaagact ggcgaaggga aatgtgaaat gtttttttcg
     3001 tatgtcgaaa agaactgtct aatcttgtaa gctgaactct aattcgtatc tgtaattaga
     3061 gttttttctt ttacgaaact ggatgaagat gatatagtag attgaaataa gatgcgaaca
     3121 aatcaattag aaaattcaaa ttaatttcta gaaatatttt agcattcttg tgtactgttc
     3181 taaattcagt ctgctataca aagtatttag gtcggtcttc ttgagtgccc cacttttctt
     3241 taaaaaaagg agtttttatg ttgaaaaaat ggcagttaaa agatgttatc ttgcttgctt
     3301 tcttgtctat cttttttggt ggggttttcg ttggttcagg atatgtgtat aatattctca
     3361 gtctactctt aacacctctt ggtttgcagg cctttgccaa tgaaatcctc ttcggtctct
     3421 ggtgtatggc tgcgcccatt gctgccatct ttgttccaag agtcggaagt gcaacgattg
     3481 gagaagtgct agctgcgctt gctgaagtcc tttatggtag ccaatttggt ctaggagctc
     3541 ttttgtctgg cttggttcaa ggtttgggaa gtgaatttgg ttttatcgta actaagaatc
     3601 gctatgaaag ttggctctct ctaactgcta atagtattgg gattacgctt gttagctttg
     3661 tctatgaata cattaagtta ggttactacg ccttttccct tccgtttgtc ctttccttac
     3721 ttgtggtacg ttttatttct gtttatttct tctgtaccat cttggttcgt gccattgtca
     3781 aactctatca tcagtttgca actggaggaa aagcatagat gggtctggaa ctacgagcga
     3841 ttcagtcccc aatcttctct gagccgtttg attttacttt tcatgcgcaa gcctttacct
     3901 tgttagttgg gagcagtggt tcaggaaaat ccagcctttt tcaagtcatt gcccaagtca
     3961 gttctcttcc ctatagtggt caagtcctga tagatgggag cgaggtcagt cagctttcta
     4021 tcatcgcacg tgtccagaag gttggcattc tcttgcaaaa tcccaatcat caatttacca
     4081 tggagaactt gtttgaggag ttgattttca ccttggagaa tatcggctat caccttcagg
     4141 aaattgattc taaaatagca gaggttgtcc agcaatgtcg ttgcgaggca atcttacacc
     4201 gtcccattca tcacctatca ggtggggaaa agcaaaaagc agcgctggct gtcctctttg
     4261 ccatgaatcc tagggtctat ctcttggatg agcccttcgc ttccattgac cgcaagagta
     4321 gaatcgagat attggagatt ctaaaagagt tggctcttga tgggaagaca gtcattttgt
     4381 gcgaccatga tttatctgac tataaagcct atatcgacca tatggttgag ctaagagacg
     4441 gaaaactaag ggaagtgttt caaatccctt cctatgagat gacacaggtt gcttcaaagg
     4501 aagttgctgc tagcccggaa ttattccata tgaaccgtgt gactggtgag cttggaaatc
     4561 gctccctctt ttcgattgct gatttcacat tctatcaagg gatttcctgt atcctgggtg
     4621 acaatggtgt cgggaaatca accctctttc gctctattct tcaatttcaa aagtataagg
     4681 ggcgcattac ttggaagggt tcggtcctga aaaagaaaaa gagtttgtat cgtgatctga
     4741 ctggtgttgt tcaggaagct gagaagcagt ttatccgagt cagtctgcga gaggagcttc
     4801 aattagatgg acctgattct gaaagaaatc agcggatttt tcaagcttta cgatattttg
     4861 atttggagca ggcagtcgat aagagtccct atcaattaag tggtggtcag caaaaaattc
     4921 ttcagctctt gaccatcttg accagtaagg cttccgtgat cttgctagat gaaccttttg
     4981 caggtttgga tgatagagcc tgccattatt tttgcaagtg gattgtggag gagaggaatc
     5041 aaggaagaag ttttctgctc attagtcatc gtttagaccc tttgatttct gtggttgatt
     5101 attggattga gatgactagt cagggtcttc ggcatgtgaa agaagtgacc attaccaaac
     5161 cacttacatc tcagagtagc aatacccaag gggaggtgag atagtatggt caaagtagca
     5221 acccagacac cgattatcag tctcttcttg ctgattttat ccttggaaac atctttcctt
     5281 ccttcgattg ctctgaatct tttggtagtc gcattttgta ttctctttat gctctattac
     5341 cgtcgattta aaatgttagc ttggatgatc atacttgcca ttttaccatc ttttgccaac
     5401 tactgggcag ttcagttaca cggagatgct tcacaggcag tcatgcttgg aacgagggcc
     5461 tttgtgacag tttgtatcgg ccttgtcttt gtttcctcta tttcactaaa agagcttctc
     5521 ttgtacttgg ctcaaaaggg gctatcacgc tcttggtcct atgccttgat tgtggtattc
     5581 aattcttttc ctctcattca gcaagaaatc aagtccctca aagaagcttg cctattacgt
     5641 ggtcaagaac tacatttttg gtcgcccttg atttacagta aggttctgat gacagtcttt
     5701 aggtggcgcc atctttacct gagagctcta tctgctcacg gatatgacga acatgcacag
     5761 ttgaagaata gctatcggac tttttatatt cctaaaaaaa caaaattaat ctacctgctt
     5821 ttctttttat tgcttcaaac cagtctattt ttataaagga gttattatgg aatttacaga
     5881 tattgcgatg gaattatcca agaaagcttg gcaggcttcc tttcatcatc cctttatttt
     5941 acaattacaa gaggggaatt tagaacctgc cattttccgc tattacctga ttcaggatgc
     6001 ctactatctg aaggccttct cagaaatcta tcatcttttg gctgataaga cttcaaacca
     6061 agagatgaaa agactcttga aacaaaatgc tcagggttta gtggagggtg agttatttat
     6121 tcgccaacaa tttttcaagg aaatggaaat cagcgaccag gaaatggagc aacatccaat
     6181 cgctccaacc tgttatcatt acatttctca tatttatagg caatttgcag aaccgaactt
     6241 agccatcgct tttgcaagct tgcttccttg tccttggtta taccatgata taggcaaatc
     6301 acttaatctt aaaccatcac caaatcctct ctatcaacaa tggattgaaa cttatattac
     6361 ggatgagtta gagcaacaga tcagagagga gggagcactg gtcaatcagc tctatcgaga
     6421 aagtgacgag acagacaagc aaaaaatgct agatgccttc cacatcagtg ttcatatgga
     6481 agccaagttt tgggaaatgg cctaccaaca ccagacatgg aagagcgatt tacagtcttt
     6541 agaaaaagga gaagaatgga agcatgagaa agcaccaact acaagttcac aaattaacca
     6601 ttttatctat gatgattgcc cttgatgtag tccttacacc tatctttcgg attgagggaa
     6661 tggcaccgat gtccagtgta gtcaatattc tagcgggaat catgatggga cctgtttatg
     6721 ccttggctat ggctacagtg acagccttta tccgtatgac gactcaaggg attccgcctt
     6781 tagctctcac aggagcgact tttggagccc ttctagcagg tctcttttat aagtacggtc
     6841 gaaaatttta cttttctgcc ttgggagaaa ttgtgggaac aggtattatt ggttctattg
     6901 tttcctatcc tgttatggta ctctttacag gatcagctgc taagcttagc tggtttatct
     6961 acacgcctcg atttttcgga gcaaccttga ttggtacagc gatttccttt attgcctttc
     7021 gatttttaat caagcaggaa ttctttaaaa aagtgcaggg atatttcttt agtgaaagga
     7081 tagactgatg caggaattta caaatccctt tcctataggc tctagttccc tcattcactg
     7141 cattaccaat gagatttctt gtgagatgct ggcaaatggg attttggctc tgggatgcaa
     7201 acctgtcatg gcagatgatc cccgtgaggt tcttgatttt actaagcaaa gtcaggctct
     7261 cttcatcaat ttggggcatt tgtcagctga gaaggagaaa gcaatccgta tagcagcttc
     7321 ttatgcagct caagtttgtc tcccaatggt agtagatgcg gttggcgtaa cgacttcatc
     7381 cattcgtaag agcttagtta aagacctttt agactataga cctacggtcc ttaaaggaaa
     7441 catgtcagaa attcgaagtc ttgttggatt aaagcaccac ggcgttgggg tcgatgcgag
     7501 tgctaaagat caagaaacgg aggatttgct tcaagtcttg aaagactggt gtcagaccta
     7561 tcctggtatg tcattcttag ttactggccc caaggacctc atcgtttcgg agaatcaagt
     7621 tgctgtactg ggaaatggct gtgcagaatt agactggata acagggacag gagatttggt
     7681 tggagcctta acagccgttt ttctcagcca aggaaagact ggttttgaag cttcttgctt
     7741 agcagtctct tatcttaata tcgctgctga gaaaatagtt gttcaaggaa tgggattgga
     7801 agaatttcgt taccaagtac tcaatcagct ttcgctccta agaagagatg aaaattggct
     7861 agataccatc aaaggagagg tttatgaata gagaagcact tagactatat ctggtaacca
     7921 atcgctatca agattccgtg gaaagctttc ttgcaaaaat tgagacggcc tgccgttcag
     7981 gggttaccat agtccaattg cgagaaaaaa atctcacaac caatcaatat tatcaactgg
     8041 caaaacaagt caaggaaata acagatgctt atcaggtacc cttgataatc gatgatcggt
     8101 tggatgtttg tcttgcggtt gatgctgctg gtctgcatat tggagatgac gaactcccag
     8161 tttcggttgc ccgacaagtc ttgggtcctg aaaaaatcct cggtgtcacc gctaaaacgg
     8221 ttaaaagagc tctggaagcg gagaaatcag gtgcagatta cttggggaca ggagccattt
     8281 ttccgacaac caccaaggaa aatgcaccca tcaccctgat ttcaaccttg aaaacaattt
     8341 gccaaacggt tgccattcca atagttgcta ttggcggctt gacttcggag aatattgatc
     8401 agcttatggg cactggcata gctggtgtag ctgttgtacg tgatttgatg caagcagaag
     8461 atattgaggc aaaaacgcaa gcctttttaa caaagttgca tgacattctt tcctaattaa
     8521 tactcaatga aaatcaaaga gtaaactaga aagctagtcg caggttgctc aaagtactgc
     8581 cttgaggttt tagataagac tgacgaagtc agctcaaaac agtgttttga agttgcagat
     8641 ggaagctgac gtagtttgaa gagattttcg aagagtataa aaactctcta attcccttaa
     8701 agtgggaact agagagtttt tttcttaatc tttaaaagtt gtatggttga ctggaccaga
     8761 accatgaccg agttgagggg catcttgaat agcttttgtg ataaaggcct tggccttatc
     8821 aactgcctgg taaagactct tgcccttggc tagttcagca gtaatcactg cagcaaaggt
     8881 acatccagta ccatgggtgt gacaggtttg aattcgtggg ctttcccaga caaattgttc
     8941 attcttggta aagaggaaat ctttagcacc acctttgaga tgtccgcctt tgataaccac
     9001 agactgagga ccaaattctt ttaaaatcag gcgaccagca cgctgcatgt cttcggggtc
     9061 atggattgaa aaaccaacaa tctcttctgc ttcaggaaga tttggcgtaa taatagttgc
     9121 tagaggtagt aagtttgttt tgagatagtc tctagcattt gagtcaatca aggcatctcc
     9181 acttgtagca accataacag gatcaaggac atagggacaa tccagttttt taagataggg
     9241 ttggatgatt tccatgattt cagtagtagc caacattcca gtttttacag cctgaggtgg
     9301 aatatcagaa aagacactct ccaattgggc tttcaacatt tgaggagaaa cgtgctcgat
     9361 tagctgaaca cctctggtat tttgagcgac aagactggtt acaacagcca ttccatagac
     9421 atctctcgct tggaatgact ttaaatctgc cataatgcca gcaccaccac tagggtcagt
     9481 ccctgcaatg gtcaaagcaa cgggtaaata agtcatctaa aacctcccaa ccaactgaag
     9541 tttgtattct taagaacaag ctagtctgtt ttagaaaggc aatagaagac tgctagtccc
     9601 cattatcatt tccacttcca tcagctagca ttacctagat tgagtcagag ggatctagca
     9661 gtcgttaatc tcagctttac gcacccctag tggttgtttt cttttttctt tagtatagca
     9721 tatttttatt gtttatatag taatatttga ctgcaaatcg tttttcaaat gattaaaatt
     9781 ctatttttcg aagaaaatat tatttctata attgacaaat gtagatttta agagtatact
     9841 gataagtgta attgacaaat gtagattttg gaggtatggt aatgcagatt tcagatgcag
     9901 aatggcaggt catgaagatt atttggatgc agggggagca gaccagtaca gatttgatta
     9961 gggttttggc agagcggttt gactggtcca agtccacggt tcagacactt ttggctcgtc
    10021 tggttgataa agagtgtttg actcggaaaa aagaaggcaa gtcctttgtt tattcagccc
    10081 ttttaactct agaccaaagt cgggatttac ttgtccaaga tatcaaagac aaggtttgtt
    10141 cccgtaggat taggaatttg ttggctgact tgattgtaga atgtgaattt actcagactg
    10201 acttggaaga cttggaagct gtgatttcag agaagaaatc aagtgctgta acagaagtaa
    10261 gatgtaattg tatgtaaagg agacgtcatg ttaaatagta ttgtaaccat tatttgtatt
    10321 gctcttatcg cgtttatctt gttttggttt ttcaaaaagc ctgaaaaatc tggacaaaaa
    10381 gcccagcaaa aaaacggata ccaagagatt cgagtggaag tcatgggagg ctatactcct
    10441 gagttgattg tcctcaagag atcagtgcca gcccgcattg tctttgaccg caaggatcct
    10501 tcaccatgtc tggatcaaat tgtttttcca gattttggtg tacatgcgaa cctgccaatg
    10561 ggggaagagt atgtagtgga aatcacgcct gagcaggctg gagagtttgg ctttgcttgt
    10621 ggtatgaaca tgatgcacgg caagatgatt gtagagtagg tggagactat gacagaaatt
    10681 gtgaaagcaa gcttagaaaa tggcattcaa aaaatccgta tccgagctga aaaaggctat
    10741 catccagccc atatccagct tcaaaaggaa attccagctg agattacctt tcatcgtgct
    10801 actccttcaa actgttataa ggaaattctg tttgaagaag aaggtatctt ggaaccaatc
    10861 ggcgtagatg aggagaaagt cattcgtttt acacctcaag aattagggcg acatgaattt
    10921 tcttgtggca tgaagatgca aaagggaagc tatatagtcg ttgagaagac tcgaaaatct
    10981 ctatctctcc tgcaacgttt ttggattact agtatcttta ctgtgcctct tgtgattctc
    11041 atgattggga tgttgacagg tagcattagt catcaagtca tgcattgggg aacctttcta
    11101 gcaacaacgc ctattatgtt agttgcaggt aagccatata tccagagtgc ttgggccagt
    11161 tttaaaaagc acaatgccaa catggatacc ttggttgcgc tgggaactct agtggcttat
    11221 ttctatagcc tagttgctct ctttgctggt ctccctgttt acttcgaaag tgctggattt
    11281 atcctctttt tcgttctttt gggagcagtt tttgaggaaa aaatgagaaa aaatacgtcc
    11341 caagctgtgg agaaattact ggacttgcaa gctaaaaccg cagaagtctt gagtgatgat
    11401 agttatgtcc aagttccttt ggaacaagtc aaggtaggcg acctgattcg agtgcgtccc
    11461 ggtgaaaaga ttgctgttga tggtgtcgta gtagaaggtg tctctagtat tgacgaatcc
    11521 atggtgacag gtgagagtct gcctgtggac aagacagttg gagatactgt cattggctca
    11581 accatcaatc atagtggaac gcttgtcttt agagcagaaa aagttggctc agagactgtt
    11641 ttggctcaga ttgtggattt tgtgaagaaa gctcagacaa gtcgtgcgcc gattcaggac
    11701 ttgacggata agatttcagg gatttttgtc ccagtagttg tcattttagg aatcatgacc
    11761 ttttgggttt ggttcgtctt gctcagggat agtgtggttg tgcttggagc tagctttgtg
    11821 tcctctcttc tctacggagt ggcggttttg attatcgcct gtccttgtgc cttgggactt
    11881 gcaacaccga cagcccttat ggtggggaca ggacgtagtg ccaagatggg ggttctcctc
    11941 aaaaatggaa ctgtcttaca ggaaatccag aaagttcaaa cccttgtctt tgataagacc
    12001 gggactttga cggaagggaa acctgtggta acagatgtca tcggcgacga agtagaagtg
    12061 tttgggttgg cagcctcctt ggaagatgct tctcaacacc cactggctga ggctatcgtt
    12121 aagcgagcga gtgaagctgg acttgagttt caaactgttg aaaattttca gtccttgcac
    12181 gggaaaggtg tttcagggcg aatcaatgga aaacaagttt tacttggaaa tgctaaaatg
    12241 ctggatggca tggatatttc taatacttat caagataaac tagaagaact agaaaaagaa
    12301 gctaagacag ttgtgttctt agctgttgac aatgaaatca aaggcttgct tgctttgcaa
    12361 gatattccta aggaaaatgc taagctagcc atcagtcagc taaaaaaacg tggtctccga
    12421 acagtcatgc tgacaggaga caatgctggt gtggcgcgtg ctattgcaga tcaaatcgga
    12481 attgaagagg tcattgcagg cgtcttgcca gaagaaaaag cccatgaaat ccataaactg
    12541 caacagtcag ggaaagtagc ctttgttggg gacggtatca atgacgctcc tgcccttagt
    12601 gtagcagatg tgggaattgc tatgggtgct ggaacagata tcgccatcga gtcagcagat
    12661 ttggtgttga caaccaataa tattttagga gtggttcgtg cctttgatat gagtaagaaa
    12721 acctttcatc gaattctact caatcttttc tgggctttta tctacaatgt tgtcggaatt
    12781 ccgattgcag caggagtctt ttcaggtgtt ggactggctc tcaacccaga attggcaggt
    12841 ctagccatgg cctttagttc tgtatctgtt ctgaccagtt cccttctgtt aaattttagt
    12901 aaaatagact aaaagtaatg actagatttc tttgttataa aacagaaatg acaacacttt
    12961 caaaactgta ttagaataga gaatagagag ttttgagcag atttttagaa aagtcagcat
    13021 aaatatgata cagtggaata gtaaaaattt ggagaacgtt tccaattcta tgtaatcgta
    13081 ttctccaagt ctaaaaaaat tgaaggagag ttatcattat gactcaaggg aaaattactg
    13141 catctgcagc aatgcttaac gtattgaaaa catggggcgt agatacaatc tacggtatcc
    13201 catcaggaac actcagctca ttgatggatg ctttggctga agacaaagat atccgtttct
    13261 tacaagttcg ccacgaagag acaggtgctc ttgcagcggt tatgcaagct aaattcggcg
    13321 gctcaatcgg ggttgcagtt ggttcaggtg gtccaggtgc gactcacttg attaacggtg
    13381 tttacgatgc agctatggat aacactccat tcctagcgat ccttggatca cgtccagtta
    13441 acgaattgaa catggatgct ttccaagagc ttaatcaaaa cccaatgtac aacggtatcg
    13501 ctgtttacaa caaacgtgta gcttacgctg agcaattgcc aaaagtaatt gacgaagcct
    13561 gccgtgctgc agtttctaaa aaaggtccag ctgttgttga aattccagta aacttcggtt
    13621 tccaagaaat cgatgaaaac tcatactacg gttcaggttc atacgaacgc tcgttcatcg
    13681 ctcctgcttt gaacgaagtt gaaatcgaca aagctgttga aatcttgaac aatgctgaac
    13741 gcccagttat ctatgctgga tttggtggtg ttaaagctgg tgaagtgatt actgaattgt
    13801 cacgtaaaat caaagcacca atcatcacaa ctggtaaaaa ctttgaagct ttcgaatgga
    13861 actatgaagg tttgacaggt tctgcttacc gtgttggttg gaaaccagcc aacgaagtgg
    13921 tctttgaagc agacacagtt cttttccttg gttcaaactt cccattcgct gaagtttacg
    13981 aagcattcaa gaacactgaa aaatttatcc aagtcgatat cgacccttac aaacttggta
    14041 aacgtcatgc tcttgacgct tcaatccttg gtgatgctgg tcaagcagct aaagctatcc
    14101 ttgacaaagt aaacccagtt gaatcaactc catggtggcg tgcaaacgtt aagaacaacc
    14161 aaaactggcg tgattacatg aacaaactcg aaggtaaaac tgagggtgaa ttgcaattgt
    14221 atcaagttta caatgcaatc aacaaacatg ctgatcaaga cgctatctac tcaatcgacg
    14281 taggtaacac tactcaaaca tctactcgtc accttcacat gacacctaag aacatgtggc
    14341 gtacatctcc actctttgcg acaatgggta ttgcccttcc tggtggtatc gctgctaaga
    14401 aagacaatcc agatcgccaa gtatggaaca tcatgggtga cggagcattc aacatgtgct
    14461 acccagacgt tatcacaaac gttcaatacg accttccagt tatcaacctt gtcttctcaa
    14521 atgctgagta cggcttcatc aagaacaaat acgaagatac aaacaaacac ttgtttggtg
    14581 tagacttcac aaacgctgac tacgctaaaa ttgcggaagc tcaaggagct gttggattca
    14641 cagttgaccg tatcgaagac atcgatgcag ttgttgcaga agctgttaaa ttgaacaaag
    14701 aaggtaaaac tgttgtcatc gatgctcgca tcactcaaca ccgtccactt ccagtagaag
    14761 tacttgaatt ggatccaaaa cttcactcag aagaagctat caaagccttc aaggaaaaat
    14821 acgaagcaga agaactcgta ccattccgtc tcttcttgga agaagaagga ttgcaatcac
    14881 gcgcaattaa ataattcctc tcgtcgaaaa tcaaatatga aacttgtaga ctttattctt
    14941 tgattttcat agagcagaac tttaaaagat cggagcaatc cggtcttttt atggaggaga
    15001 gtaaatgaat ttaaatcaat tagatattat cgtttcaaat gttccccaag tctgtgctga
    15061 cttggagcat atcttggata aaaaggcaga ttatgctgat gatggttttg ctcagtttac
    15121 gattggtagt cactgcctta tgttgtcaca aaatcatttg gttcctttgg aaaactttca
    15181 gtcaggaatc attattcata tcgaggttga ggatgtagac cagaactaca aacggttgaa
    15241 cgagcttggt ataaaggttt tacacggacc aactgtaacc gattggggaa cagagtcctt
    15301 attagttcaa ggacctgctg gtctagtgct tgatttttat cgtatgaaat aggtcgcgta
    15361 gtcatttgac gttaacctta gctattttta aaatagaaat tgagaatatg aactattgaa
    15421 agatcggagc aatccggtct ttttatataa agaaattgca tataatactc atctgctttc
    15481 aaaaagcatt ctagtccatc tccgattaac gatggacttt atcacctcct tctccaatcc
    15541 ttgtatgaca tcttggagtt gattcatgac atcttccaaa gttcgaaagg ctttattctt
    15601 aaatccacgt ttacgaatct ctttccacac ttgttcaatg gggttcatct ctggtgtgta
    15661 tggaggaata aatgcaaagc caatattagt cggaatcttt aaggtacttg atttatgcca
    15721 tatag
//
LOCUS       DAVHLA010000044        15667 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVHLA010000044 DAVHLA010000000
VERSION     DAVHLA010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15667
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.044"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            101..256
                     /locus_tag="VVO77_001709"
                     /pseudo
     CDS             101..256
                     /locus_tag="VVO77_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            456..3731
                     /gene="rexB"
                     /locus_tag="VVO77_001710"
     CDS             456..3731
                     /gene="rexB"
                     /locus_tag="VVO77_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEU5693693.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPVKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMNFLDLENLTDEDKRADLLLIFEKVTDYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQIALVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYCFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQIFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPISPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWLEKIREE
                     LNR"
     gene            3728..7378
                     /gene="addA"
                     /locus_tag="VVO77_001711"
     CDS             3728..7378
                     /gene="addA"
                     /locus_tag="VVO77_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEU5693694.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAANELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQESDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FAKLGQLSDQITILDYQERYHQDTWELAKTFQTFMSHFVEVYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYIFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLTSLTETLK
                     QVQTSQAVRDKINLDKILAFFDTALGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            7548..8726
                     /locus_tag="VVO77_001712"
     CDS             7548..8726
                     /locus_tag="VVO77_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693695.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERDIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            8935..15009
                     /locus_tag="VVO77_001713"
     CDS             8935..15009
                     /locus_tag="VVO77_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU5693696.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGEPEVQPTLPEAVVSDKG
                     VPEVQPELPEAVVSDKGVPEVQPELPEAVVSDKGEPEQVAPLPEYKGNIEQVKPETPV
                     EKTKEQGPEKTEEVPVKPTEETPVNPNEGTTEGTSIQGAENPVQPAEESTTNSEKVSP
                     DTSSENTGEVSNKPSDSTTSVGESNKPEHNDSKNENSEKTVEEVPVNPNEGTVEGTSN
                     QETEKPVQPAEETQTNSGKIANENTGEVSNKPSDSKPPVEESNQPEKNGTATKPENSG
                     NTTSENGQTEPEPSNGNSTEDVSTKSNTSNSNGNEEIKQENELDPDKKVEDPEKTLEL
                     RNVSDLELYSLSNGTYKQHISLEQVPSNPNSYFVKVKSSSFKDVYLPVASISEERKND
                     KILYKITAKVEKLQQEIESRYKDNFPFYLAKKGTEETTNFTSFSNLVKAINQNLSGTY
                     HLGASLNANEVELSTDDKSYIKGTFTGQLIGEKDGKHYAIYNLKKPLFENLSGATVEK
                     LSLKNVAISGKNDIGSLANEATNGTKIKQVHVDGVLAGERGVGGLLAKADQSSIAESS
                     FKGRIVNTYETTDSYNIGGLVGHLTGKNASIAKSKATVTISSNTNRSDQTVGGLAGLV
                     DRDAQIQDSYAEGDINNVKHFGRVAGVAGNLWDRTSGDVRHAGSLTNVLSDVNVTNGN
                     AITGYHYTGMKVANTFSSKANRVFNVTLEKNEVVSKESFEERGTMLDASQIASKKAEI
                     NLITPPIVEPLSTSGKKDSDFSKIAHYQANRALVYKNIEKLLPFYNKATIVKYGNLVK
                     ENSILYQKELLSAVMMKDDQVITDIISNKQTANKLLLHYKDHSSEKFDLRYQADFANL
                     AEYSIGDSGLLYTPNQFLYHQDSIINQVLPELNRVNYQSDAVRNTLGISPEVKLTELY
                     LEEQFTKTKEHLAENLKKLLSSDAGLVTDNEVMTGYIIDKIKRNKEALLLGMSYLERW
                     YNFSYGQVNVKDLVMYHPDFFGKGNTSPLDTLIELGKSGFNNLLAKNNVDTYAISLAS
                     HHGTTDLFSTLENYRKVFLPDKTNNDWFKSQTKAYIVEEKSNIEEVKTKQGLVGTKYS
                     IGVYDRITSATWKYRNMVLPLLTLPERSVFVISTISSLGFGAYDRYRNKEHQANGDLN
                     SFVEKSAHETAERQRDHYDYWYRILDEKGREKLYRNILLYDAYKFGTNHTEGKATEVA
                     DFDSPNPAMKHFFGPVGNKVGHNGHGAYATGDAVYYMGYRMLDKDGAITYTHEMTHNS
                     DQDIYLGGYGRRSGLGPEFFAKGLLQAPDQPSDATITINSILKHSKSDSKEGERLQVL
                     DPTTRFKDATDLQKYVHNMFDVVYMLEYLEGKSIVKKLNVYQKIEALRKIENQYLTDP
                     ADGNDVYATNVVKNLTEDEAKKLTSFDSLIDNNILSAREYKAGTYERNGYFTIKLFAP
                     IFSALSGEKGTPGDLMGRRIAFELLAAKGFKDGMVPYISNQYEEDAKQQGQTINLYGK
                     ERGLVTDELVLKKVFDGKYKTWAEFKTAMYQERVDQFGNLKQVTFKDPTKPWPRYGTK
                     TINNVDELQKLMDEAVLQDAKERNYYYWNNYNPETDSAVHKLKRAIFKAYLDQTNDFR
                     RSIFENKK"
     gene            15053..>15667
                     /locus_tag="VVO77_001714"
     CDS             15053..>15667
                     /locus_tag="VVO77_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU5693697.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSVFLGSLLFAPSVVGTSTYHYLDYS
                     TLTQTERVQLKQGRPDESKESYALVYEKDALPNTGSSQSIMTALGLLAIGSLIVIITK
                     DKKRKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVDYLELDDR
                     TVSPVEQPKVVTDKGEPEVQPALPEAVVTGKGKTEVQPTLPEAVV"
BASE COUNT         5244 a         2989 c         3255 g         4179 t
ORIGIN      
        1 aactttttta cgaaaatcta ttgaatatgc cataagaaga ttataccaca ttgtgtccta
       61 tttttggttc attttactat agttcaatca ttctatcaag aatattgaat atataaaggc
      121 acgtaatatt aaaacttctt ctgatatcga attagagtcc gatgttgatg gcgataaatc
      181 agacaatcta cccgtcgaca ttaagacact gggacaacac attgaagtgt attccgtacc
      241 taagaaacaa tcataaaact caaagccttg ttaccgaggc ttttttatta tatgattttc
      301 agtggccaga cttattctat ctaatacaag taaagctaag tatttaagat ttagcagatg
      361 atgaagaaaa gaaaggatgg cctaaatatt ttaacagatt tacgaggcta atcatggtat
      421 aatatagggt gatgaaaaat tccaacgagg ctgagatgaa attactttat actgatattc
      481 gaacttcttt gacagaaatt ctaacaagag aggcagaaga gctagttgca gctggcaagc
      541 gggtcttcta cattgccccc aactctcttt cttttgaaaa ggaacgcgcc gtgctggaat
      601 gcttgtccca gcaggcttct ttttcgatta ccgtcacgcg ctttgctcaa atggctcgtt
      661 atctggtctt gaatgattta ccagttaaaa ctactcttga tgatatcggt cttgggttgg
      721 ccttttacaa atgccttgcc gaactcgatc ccaaggactt gcgtgtttat ggagctatta
      781 agcaggatcc tcaattgatc cagcagttaa ttgagcttta ccatgagatg accaaatctc
      841 agatgaattt tttggacttg gagaatttaa cagatgagga taagagggcg gatttactct
      901 tgatttttga gaaagtaaca gactatctta atcaaggtca gttagcccag ggaagtcagt
      961 tgtcccattt gattgaggct attgagaatg acaaggtaag tagtgatttt aatcaaatcg
     1021 ccttggtcat tgacggcttt actcgttttt ctgctgagga agagcgggtt gtggacttac
     1081 ttcacggcaa aggtgttgag attgttatcg gggcttatgc tagtaagaaa gcctatacca
     1141 gtccttttag cgagggcaat ctctaccaag ccagcgtaaa atttctccat catctggctt
     1201 ctaaatacca aacgcccgct caggactgtt ctcaaactca tgagaagatg gatagttttg
     1261 acaaggcctc tcgtttgttg gagtcttctt atgacttttc agaactcgct ttggatgtcg
     1321 atgagaaaga ccgtgaaaat ttacaaatct ggtcttgttt gacgcaaaag gaggagttgg
     1381 agctagtagc ccgtagcatt cgtcagaaat tacatgagaa ctcagacctg agctacaagc
     1441 attttcgtat tctcttgggg gatgtagctt cttaccagtt atctctcaaa accatttttg
     1501 accagtatca gattcctttt tatcttggta gaagcgaagc catggctcat catcccttga
     1561 ctcagtttgt cgagtctatt ttagctttaa aacgttactg ttttcgtcag gaggatttga
     1621 ttaatcttct tagaactgac ttgtatactg acctcagtca gtctgatatt gatgcttttg
     1681 agcaatatat ccgctatctt ggtatcaatg gcttgccagc ctttcagcaa atcttcacca
     1741 aatcccacca tggaaaattt aatcttgagc gtttgaatgt cctccgcctg agaattttag
     1801 cacctcttga aaccctcttt gccagccgaa aacaaaaggc tgaaaacctc ctacaaaaat
     1861 ggagtgtctt tctaaaagaa ggagctgtga ccaagcagtt acaagatttg acaaccactt
     1921 tggaagctgt agaacaggaa agacaagccg aagtttggaa ggctttctgc catgttttag
     1981 aacaatttgc gactgttttt gctggttcac aggttagtct ggaagacttc ctagccttgc
     2041 tccattctgg aatgagtttg tcccaatacc gtaccattcc agcaacagtg gacactgttc
     2101 tggtgcagag ttacgatttg attgcaccat tgactgctga ctttgtctat gctattggac
     2161 taactcagga caatttacca aaaatttctc aaaacaccag tcttctgaca gatgaagaaa
     2221 ggcaaaatct aaaccaagcg accgaagaag gcgttcaatt actgattgcc agcagtgaaa
     2281 atctcaagaa aaatcgctac actatgcttt ccttagtcaa ttctgctcgt aagcagttgt
     2341 tcttgtcggc tccaagcctt tttaacgaaa gtgaaagtaa ggaatctgcc tatcttcaag
     2401 agttgatcca ttttggattt aggcggagag agaagaggat gaatcacaaa ggactgtcta
     2461 aggaggatat ggggtcctat cacagtcttt tgtctagtct ggttgcctat caccagcagg
     2521 gtgagatgag cgatactgag caagatttga cttttgtcaa ggttctgtcg cgtgtcatag
     2581 gtaaaaaact agatcagcaa ggtctggaaa atccagccat cccaatcagt ccaagcagca
     2641 agaccttagc caaggacacc ttgcaagctc tctatcctgc caaacaggag ttttacctgt
     2701 ctacgtcggg tttgacagag ttttatcgca atgaatacag ttatttccta cgctacgttt
     2761 taggcttgca ggaggaatta cgtttgcgtc ctgatgcccg tagtcacggg aatttcttgc
     2821 atcgtatctt tgaacgcgcc ttgcagttgc ctaatgaaga ttcctttgac caacgtctag
     2881 aacaagctat tcaagaaacc agtcaagaac gcgaatttga agctatttat caagaaagtt
     2941 tggaagccca gtttaccaag gaagttttgc ttgatgttgc acggacaact ggacatattc
     3001 tccgacacaa tccagccatc gaaacaatca aagaagaagc aaattttggt ggaaaagacc
     3061 aagcctttat tcaattagac aatggacgca gtgtctttgt acgaggcaag gtggaccgga
     3121 ttgaccgttt gaaagctaat ggagcgatag gagtagtaga ctacaaatcc agtctgactc
     3181 agttccagtt tcctcatttc tttaatgggc tcaattctca gttaccaacc tatcttgctg
     3241 ccctaaaaag agaaggggag cagaactttt tcggcgccat gtacttggaa atggctgaac
     3301 ctgtccaatc tctgatggcg gtaaaaagtc tggcaggagc agtggtagaa gccagcaaat
     3361 ctatgaaata ccaagggctc ttcttggaaa aagaaagcag ttatttaggc gaattttata
     3421 acaaaaacaa ggcgaatcaa ctgacagatg aggaatttca gctcctactg gactacaatg
     3481 cctatcttta caagaaagct gctgagaaga ttttagcagg ccggttcgcc atcaatcctt
     3541 atactgaaaa tggcagaagc attgccccat acgtccagca acatcaggct attacaggct
     3601 ttgaagccaa ttaccatctg ggccaagccc gtttcctaga aaagttggac ctagctgatg
     3661 gcaagcgtct ggtcggagaa aaactcaagc aagcttggct tgaaaaaata agagaggagt
     3721 tgaatcgatg aagcttattc cctttttaag tgaggaggag attcaaaaac tgcaagaagc
     3781 agaagcaaat tcgagcaagg aacagaagaa aactgccgag caaatcgaag ctatctacac
     3841 ttctggccag aatatcctgg tctcagcatc ggctggttct ggaaagacct ttgtcatggc
     3901 agagcgcatt ctggaccaat tggcgcgtgg tgtcgaaatt tctcaactct ttatctcaac
     3961 ctttaccgtc aaggctgcaa atgaacttaa agaacgttta gagaaaaaaa tcagcaagaa
     4021 aatccaagaa acagatgatg tcgacctcaa acaacacttg ggacgccagt tggcagacct
     4081 accaaacgct gccatcggaa ccatggactc tttcacacaa aaattccttg gcaaacatgg
     4141 ttatctgctt gatattgcac ctaatttccg tattttacaa aaccaaagcg agcaacttct
     4201 tctcgaaaac gaagtctttc atgaggtctt tgaagcgcat taccaaggta aacagaaaga
     4261 gacctttagt catttgctga aaaactttgc tgggcgtggc aaggacgaac ggggtctgcg
     4321 ccagcaggtc tataaaatct atgacttcct ccaatccacc agtaatcctc aaaagtggct
     4381 gagtgaatct ttcctcaaag gctttgagaa agctgatttt accagtgaaa aagaaaaact
     4441 gactgagcaa atcaaacaag ccctttggga tttggaaagc tttttccgtt accatctgga
     4501 taacgatgcc aaggagtttg caaaggctgc ctatttagaa aatgttcagt taattctgga
     4561 tgaaattggc tccctaaatc aggagtccga tagtcaggct tatcaggcag tgcttgcgcg
     4621 tgttgtcgcc atctctaagg agaaaaacgg tcgagctctg actaatgcca gtcgtaaggc
     4681 tgatttgaag cccctggctg atgcctacaa cgaagagaga aagacccagt ttgctaaact
     4741 aggacaatta tcagaccaga taaccattct cgactatcaa gaacgttatc atcaagacac
     4801 atgggaacta gctaaaacct tccaaacctt tatgagtcat tttgtggagg tttatcgtca
     4861 gcgcaaacgc caggaaaatg cctttgaatt cgctgatatc agccattaca ccattgagat
     4921 tttagagaat ttcccacaag ttcgtgagtc ttatcaggag cgcttccatg aagtcatggt
     4981 cgatgagtat caggatacca accatattca agaacggatg ctggaattgt tgtctaatgg
     5041 ccacaatcgc tttatggtgg gagatatcaa gcaatccatc tatcgtttcc gtcaggcaga
     5101 cccgcagatt ttcaatgaga aattccaacg ctatgcgcaa aatccccaag aaggcaagct
     5161 cattctcctc aaggaaaatt tccgtagtag ttcagaagtg ctgtcagcaa ccaatgatgt
     5221 ctttgaacgt ctcatggacc aagaggtcgg cgaaatcaac tatgataaca agcaccagct
     5281 tgtttttgcc aataccaaac tgactcccaa tccagacaac aaggcagaat ttctcctcta
     5341 cgacaaggac gatacaggtg aggaagaaga gagtcaaaca gaaacgaaac taacaggcga
     5401 aatgcgctta gttatcaagg agattctgaa acttcatcaa gaaaaaggtg ttgcctttaa
     5461 ggaaattgcc cttctgacct ccagccgcag tcgtaatgac cagattctcc tcgccctgtc
     5521 tgagtacgga attcctgtca aaactgacgg agagcaaaac aattatctcc aatccctaga
     5581 agtgcaagtc atgctagaca ctcttcgtgt cattcacaat cccctgcaag actacgcctt
     5641 ggttgccctt atgaagtctc caatgtttgg ttttgatgag gatgagctag cacgtttgtc
     5701 ccttcagaaa gcagaggata aagtccacga aaatctctat gagaaactgg tcaatgcaca
     5761 aaaaatggca agtagtcaaa aaggcttgat tcacacagct ctagctgaaa aactaaagca
     5821 attcatggat atcctagctt cttggcgctt gtatgccaaa acccattctc tctatgactt
     5881 gatttggaag atttacaacg accgttttta ttatgactat gttggggctt tgccgaatgg
     5941 tcctgctagg caggccaatc tctatgccct agcactgcgt gctgatcaat ttgaaaagag
     6001 caatttcaaa ggtttgtcgc gttttattcg tatgattgac caagtcttag aagcccagca
     6061 cgatttggca agcgtagccg tcgcaccgcc aaaagatgca gtagagctca tgaccatcca
     6121 caagagtaaa gggctggagt ttccttacat ctttatcctc aatatggatc aagatttcaa
     6181 caagcaagac tctatgtcag aagtcattct cagtcgtcag aatggtcttg gtgtcaaata
     6241 tattgccaag atggagacag gggcagtaga agaccactat cctaaaacca tcaaactctc
     6301 cattcctagt ctgacctata ggcagaacga agaggaatta cagctagcaa gctattctga
     6361 gcagatgcgt ttgctgtatg ttgctatgac gcgggctgag aaaaagctct atcttgtcgg
     6421 caagggttct cgtgaaaagc tggaatccaa ggaataccca gcagccaaaa atgggaaact
     6481 aaatagcaat actagactgc aagcacggaa tttccaagat tggctttggg ctatcagtaa
     6541 agtgtttact aaggacaagc tcaactttag ttatcgtttt attggcgaag atcagttgac
     6601 cagagaagct atcggagagt tggaaaccaa gagtcctctc caagatagct cccaagcaga
     6661 caatcgtcag tcagatacca tcaaagaagc tctggaaatg ctgaaggagg tggaagttta
     6721 taatactctt caccgcgcag ctattgaact tcctagtgtt caaaccccaa gtcaaatcaa
     6781 gaaattctac gaaccagtta tggatatgga aggtgtcgag attgctggtc aaggtcagtc
     6841 agtaggcaag aaaatcagct tcgatttgcc agatttttca accaaagaaa aggtaactgg
     6901 agctgagatt ggtagtgcta ctcacgaact catgcagaga attgacctca gccagcaact
     6961 aacccttact agcctaacag aaacactcaa acaagttcaa actagccaag ctgtcagaga
     7021 caagatcaat cttgataaaa ttcttgcttt ctttgacaca gcactcggtc aggaaattct
     7081 tgctaatacc gaccatctct atcgcgagca acctttctcc atgctcaaac gagaccaaaa
     7141 gagtcaggaa gactttgttg tccgtggtat ccttgatggc tatctgcttt acgaaaacaa
     7201 aattgttctg ttcgactaca agacagaccg ctatgatgaa ccaagtcaac tcgtagaccg
     7261 ctatcgtggt cagttagctc tatacgaaga ggctttatca cgagcctatt cgattgaaaa
     7321 tattgaaaaa tacttgattt tactcggtaa agacgaggtt caagttgtaa aagtataact
     7381 tatactcttc gaaaatctct tcaaaccacg tcagcttcgc cttgctgtat atatggttac
     7441 tgacttcgtc agttctatcc acaacctcaa aacagtgttt tgagctgact gcggctagct
     7501 ttctagtttg ctctttgatt tttattgagt attagaaagg agacctcatg acacttccag
     7561 ttagaaaatc cctgcacgat gcagttttac aggcttcgaa agcggatact tgggaacaag
     7621 ctaccaagga atggaatgaa gtttccttga tttttaacgg tatcggccgt agcaattgtg
     7681 tctgtggaaa tgccatcaaa tacgcttatg aactctttaa cggtgtcaca ggccaacgcc
     7741 tctttccaat tggtagcgac tgtgttcgtc attttcatcg attgtccctt gaccagcaat
     7801 tggaagagga agaaaaactg ctcagaaagg ttgaaaatct aaccagaaaa gctcagaaaa
     7861 aggaaaaaat caaggtcaat aaaagtgact ttgacgagcg acttctaaaa tggctctggg
     7921 aaaaaggtgt tttcaaaccc aatcgtggca atcaatttgc gcctgagaga gactaccagc
     7981 ttttcctaga agtctttcag ggaggaagtt ggaccaaggc ggaaccaaag aaaaaggctc
     8041 ggatggaaga agtccttgaa aagtgtatca aacccttttt acttgggaaa tcggatgacc
     8101 aactctacct tgtcaagcta ggcaaggaga aaattgacta cgaacaagaa ctccgtatcc
     8161 aggcagagaa agaacgcaag aagagggata aaatcgccaa gcaatatgca gacaatctgg
     8221 ttctagccat gggacccgca gagcgtgctt atcaagatta ctttggcttt acagagaccc
     8281 tgactcaaga agaacgcaag tgggaaaaaa ttctttttgg taaaaataga gcagaacggg
     8341 atatcaaggc caaacaatac caaaaagagc tggaaaaaga ccaacgaatt gccagtcagg
     8401 atccaattga aagaaaacag aagcagactt ggctcctcaa ttcctatttt cgtgagcttc
     8461 ctgaagaaaa agctcgattt tctaggctct tattagaata tcgaaaaagt ggtgaagtac
     8521 ccttttcaac tgaatacctg tccgatcatc tcatcgactt tttctataaa atgaaagcct
     8581 ttgaatttga aatcgcacca gaacaagtcc gagattttct aaaaaaaagc ctgcaggaag
     8641 accatcgctc atcagcacaa ggaagctgga tagaaggaat tctcctcaac tgcctcaaac
     8701 catttttaga acgattagtg atatgagtaa cacctaccgt gtaaatttca tggtaggtgt
     8761 tattgtacct caaaataata taaaacaaag tatgaaagcg catctcaatt ttaagacttt
     8821 tttgtaaatt aagagtataa ttaaggtata ctgccttttc tatagataat atataataca
     8881 ctaatataat aaaggtcttt gtaacatata taaattttat ttcaaggagg aataatggaa
     8941 aagtattttg gtgaaaaaca agagcgtttt tcatttagaa aattatcagt aggacttgta
     9001 tctgcaacga tttcaagttt attttttatg tctgtattag ctagttcatc tgtggatgct
     9061 caagaaactg cgggagttca ctataaatat gtggcagatt cagagctatc atcagaagaa
     9121 aagaagcagc ttgtctatga tattccgaca tacgtggaga atgatgatga aacttattat
     9181 cttgtttata agttaaattc tcaaaatcaa ctggcggaat taccaaatac tggaagcaag
     9241 aatgagaggc aagccctagt tgctggtgct agcttagctg ctctgggaat tttaattttt
     9301 gctgtttcca agaaaaaggt taagaataaa acggtattac atttagtatt ggttgcggga
     9361 ataggaaatg gtgtcttagt ttcagtccat gctttagaaa atcatctttt gctaaattac
     9421 aatacggact atgaattgac ctctggagaa aaattacctc ttcctaaaga gatttcaggt
     9481 tacacttata ttggatatat caaagaggga aaaacgactt ctgattttga agtaagtaat
     9541 caagaaaaat cagcagccac tcctacaaaa caacaaaagg tggattataa tgttacacca
     9601 aattttgtag accatccatc aacagtacaa gctattcagg aacaaacacc tgtttcttca
     9661 actaagccga cagaagttca agtagttgaa aaacctttct ctactgaatt aatcaatcca
     9721 agaaaagaag agaaacaatc ttcagattct caagaacaat tagccgaaca taagaatcta
     9781 gaaacgaaga aagaggagaa gatttctcca aaagaaaaga ctggggtaaa tacattaaat
     9841 ccacaggatg aagttttatc aggtcaattg aacaaacctg aactcttata tcgtgaggaa
     9901 actatagaga caaaaataga ttttcaagaa gaaattcaag aaaatcctga tttagctgaa
     9961 ggaactgtaa gagtaaaaca agaaggtaaa ttaggtaaga aagttgaaat cgtcagaata
    10021 ttctctgtaa acaaggaaga agtttcgcga gaaattgttt caacttcaac gactgcgcct
    10081 agtccaagaa tagtcgaaaa aggtactaaa aaaactcaag ttataaagga acaacctgag
    10141 actggtgtag aacataagga cgtacagtct ggagctattg ttgaacccgc aattcagcct
    10201 gagttgcccg aagctgtagt aagtgacaaa ggcgaaccag aagttcaacc tacattaccc
    10261 gaagcagttg taagcgataa aggcgtacca gaagttcaac ctgaattacc cgaagcagtt
    10321 gtaagcgata aaggcgtacc agaagttcag cctgaattac ccgaagcagt tgtaagtgat
    10381 aaaggtgaac cagagcaggt agcaccattg ccagaatata aggggaatat tgagcaagta
    10441 aaacctgaaa ctccggttga gaagaccaaa gaacagggtc cagaaaaaac ggaagaagtt
    10501 ccagtaaaac caacagaaga aacaccagta aatccaaatg aaggtactac agaaggaacc
    10561 tcaattcaag gagcagaaaa tccagttcaa cctgcagaag aatcaacaac gaattcagag
    10621 aaagtatcac cagatacatc tagcgaaaat actggggaag tatccaataa acctagtgat
    10681 tcgacaacct cagttggaga atcaaataaa ccagaacata atgactctaa aaatgaaaat
    10741 tcagaaaaaa ctgtagaaga agttccggta aatccaaatg aaggcacagt agaagggacc
    10801 tcaaatcaag aaacagaaaa accagttcaa cctgcagaag aaacacaaac aaactctggg
    10861 aaaatagcta acgaaaatac tggagaagta tccaataaac ctagtgattc aaaaccacca
    10921 gttgaagaat caaatcaacc agaaaaaaac ggaactgcaa caaaaccaga aaattcaggt
    10981 aatacaacat cagagaatgg acaaacagaa ccagaaccat caaacggaaa ttcaactgag
    11041 gatgtttcaa ccaaatcaaa cacatccaat tcaaatggaa acgaagaaat taaacaagaa
    11101 aatgaactag accccgataa aaaggtagaa gatccagaga aaacacttga attaagaaat
    11161 gtttccgacc tagagttata cagtttgtca aatggtactt ataaacaaca catttcgtta
    11221 gagcaagttc caagcaatcc aaatagctac tttgttaaag tgaaatcttc ttcattcaaa
    11281 gatgtatacc taccagtagc atcaatatca gaggaaagaa aaaatgataa aatcctttat
    11341 aaaatcacag caaaagtaga gaagcttcag caggagatag aaagcagata taaagataat
    11401 tttcccttct atctagctaa gaagggaaca gaagaaacaa caaactttac ttcctttagt
    11461 aatctggtca aagctataaa ccaaaatctc tctggaacct atcatttagg agctagcctg
    11521 aatgctaacg aagtggagct tagtactgat gataaatcct atatcaaggg aacctttact
    11581 ggtcagttga ttggtgaaaa agatggtaag cattatgcta tttacaactt gaaaaagcct
    11641 ctttttgaaa acttgagtgg tgctacagta gaaaaactga gtctaaaaaa tgttgctatt
    11701 tcagggaaaa atgatattgg ttcactggca aatgaagcta cgaatggcac aaagattaaa
    11761 caagttcatg ttgatggtgt tctggctgga gaacgtggtg tcggtggttt gttggctaag
    11821 gcagaccaat caagcatcgc agagagcagt ttcaagggaa gaattgtcaa tacctatgaa
    11881 acgactgatt cctacaatat tggcggtctg gtcggtcatt taacaggaaa aaatgcgtct
    11941 attgctaaat ccaaagcgac agtaaccatt tcgtcaaaca ccaataggtc agatcagact
    12001 gtcggtggtc ttgcaggtct agtagaccga gatgcacaga tccaagatag ctatgctgaa
    12061 ggtgatatca acaatgtcaa gcactttggt agagtcgctg gagtggcagg caatttgtgg
    12121 gatcgaactt ctggtgatgt taggcatgct ggaagtttga ccaatgttct cagcgatgtt
    12181 aatgtaacaa acggaaatgc catcactgga taccactata caggaatgaa ggtagctaat
    12241 acatttagta gtaaggctaa tagagttttc aatgtcactt tagagaagaa tgaggtcgtc
    12301 agcaaagaat ccttcgagga aagaggaaca atgctagatg cttctcaaat tgcaagcaaa
    12361 aaagcagaaa tcaatcttat cactccacca atagtggaac ccctctcaac aagcggtaag
    12421 aaagacagtg atttttctaa gatagcccat tatcaagcca accgtgcttt ggtttataag
    12481 aacattgaaa aattgttacc tttctataac aaggcgacca tcgtgaaata cggaaacctg
    12541 gttaaggaga acagtatctt atatcaaaaa gaactcttgt ctgcagttat gatgaaggat
    12601 gaccaagtaa tcacagatat tatttccaac aaacagactg caaacaaact cttgcttcac
    12661 tacaaggacc attcatctga aaagtttgat ctcaggtacc aggctgattt tgccaatttg
    12721 gcagaatata gcattggaga tagtgggctt ctctatacgc caaatcaatt cttgtatcat
    12781 caagattcta ttattaacca agtgctgcct gaattgaatc gagtaaatta tcaatcagat
    12841 gctgttagaa atacacttgg aatttcacca gaagtgaagc taacggagtt atatcttgaa
    12901 gaacaattta ccaaaacgaa agagcatcta gcagagaact tgaaaaaact tttatcatct
    12961 gatgcaggtt tagtaacaga caatgaagtt atgacaggat atataataga taaaattaaa
    13021 cggaataagg aagccttact tcttggaatg agttatttag aacgttggta taactttagc
    13081 tatggtcaag tgaatgtcaa agacctagtt atgtatcatc cggacttctt tggtaaagga
    13141 aatacttcac cattagatac tctgattgag ttaggtaaat ctggctttaa caatcttctt
    13201 gctaaaaaca atgtcgatac ttatgctatc agccttgcca gccatcatgg aacgacagat
    13261 ttgtttagca cgttggaaaa ttaccgaaaa gtctttctac cagataaaac caataatgac
    13321 tggtttaaat cacagactaa ggcttacatt gtcgaagaaa aatccaatat cgaagaggtg
    13381 aaaacgaagc aaggactagt tggcactaag tattctattg gtgtctatga ccgtatcact
    13441 agtgccacat ggaaataccg taatatggta ctacctctac ttaccttgcc agaaagatcc
    13501 gtatttgtca tttcaaccat atctagtcta ggttttggtg cttatgatcg ctatcgtaat
    13561 aaagaacatc aagcaaatgg tgatcttaat agctttgttg aaaagagtgc tcacgaaaca
    13621 gcagagcgtc aacgagatca ctatgattat tggtatcgta ttctagatga aaaagggcgt
    13681 gaaaagcttt atcgaaatat cttgctttat gatgcctata aatttggaac taatcatact
    13741 gaaggaaagg ctacagaagt agcagatttt gatagtccaa atcctgcaat gaaacatttc
    13801 tttggacctg ttggaaataa ggttggacat aatggacatg gtgcttatgc tacaggggat
    13861 gcagtatatt atatggggta tcgcatgcta gataaggatg gagctattac gtatactcat
    13921 gagatgacgc ataattcaga tcaagatatt tatcttggtg gttatggaag aagaagtgga
    13981 cttggacctg agttctttgc taaaggctta ctacaagcac cagaccaacc aagtgatgca
    14041 acgattacta tcaattctat attgaaacat tcaaaatctg atagtaaaga aggagaacga
    14101 ttacaagtac ttgatccaac tacgagattt aaagacgcaa cagatcttca aaaatacgtc
    14161 cacaatatgt ttgatgttgt ttatatgttg gaatatctcg aaggtaaatc tattgttaag
    14221 aaattaaatg tatatcagaa aatagaagct ctcagaaaaa tcgagaacca atatctaaca
    14281 gatcctgctg atggaaatga tgtttatgct actaatgttg tgaaaaattt gactgaagat
    14341 gaagctaaaa aattgacgag ctttgatagt ttgattgaca ataacattct ttcggctcgt
    14401 gagtataagg ctggcactta tgagagaaat ggctacttta ctataaaact ctttgcacca
    14461 atcttttcag cattgagcgg tgagaaagga actccaggtg accttatggg acgaaggata
    14521 gcttttgaac ttctagctgc taaaggattt aaagatggta tggtaccata tatttccaac
    14581 caatacgaag aagatgctaa acaacaaggg caaactatca atctttatgg taaagaacgg
    14641 ggcttggtga ccgatgagct tgttttgaaa aaggtatttg atggtaagta taaaacttgg
    14701 gcagaattta agacagctat gtaccaagaa cgggtggatc agtttggaaa cttgaagcag
    14761 gtgaccttta aagatccgac aaaaccatgg ccaagatatg gcacaaagac tatcaataat
    14821 gtggatgaat tgcagaaact aatggatgaa gctgttttgc aggatgcaaa agaacgtaat
    14881 tattattatt ggaataacta taatccagaa acggacagtg ccgtccataa gttgaagaga
    14941 gcaatcttta aagcctatct tgaccaaaca aatgatttta gaagatcaat ttttgagaat
    15001 aaaaaatagt gtttactatt aggaaataaa aagtgaatgt ggaggattag aattgtcatt
    15061 attaaaaaaa gataaatttt ccattcggaa aataaagggt attgttggtt cggtattctt
    15121 ggggagtctt ttatttgcac cgtcagttgt tggtacatcg acttatcatt acttagatta
    15181 tagtactttg acacaaactg aacgtgttca actcaaacaa ggtagacctg atgaatcaaa
    15241 agagtcatat gctttggttt atgaaaaaga cgcattacca aacacaggaa gttctcaatc
    15301 tattatgact gcattgggtt tgttagctat cgggagtctt attgtgatta tcacaaaaga
    15361 taaaaagagg aaaaaaatcg ctacattttt gattgtaggg gcgacaggtt tagttacact
    15421 atcaactgct tcagcactta atttgaatgc taacatccat gagtctggac gtgatggtgt
    15481 gttgcaaatt tctggttaca gatatgttga ttacttggag cttgatgata gaactgtttc
    15541 tccagttgag caacccaaag ttgtgaccga caaaggcgaa ccagaagttc agccagcgtt
    15601 accagaagct gttgtaactg gaaaagggaa aactgaagta caaccgacat taccagaagc
    15661 tgttgtg
//
LOCUS       DAVHLA010000045        15643 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVHLA010000045 DAVHLA010000000
VERSION     DAVHLA010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15643
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.045"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            170..1663
                     /locus_tag="VVO77_001715"
     CDS             170..1663
                     /locus_tag="VVO77_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEU5693698.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            1676..2785
                     /locus_tag="VVO77_001716"
     CDS             1676..2785
                     /locus_tag="VVO77_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU5693699.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLREHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKRLITKRK
                     LQLDELNLLVKSRFNEMFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLN
                     TKNVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHL
                     RINSGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLA
                     LQNEFADFVVQVDKSQFACEIAIKVWRNSLKFSII"
     gene            2815..6100
                     /locus_tag="VVO77_001717"
                     /pseudo
     CDS             2815..6100
                     /locus_tag="VVO77_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            6344..6445
                     /locus_tag="VVO77_001718"
                     /pseudo
     CDS             6344..6445
                     /locus_tag="VVO77_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(6686..7156)
                     /locus_tag="VVO77_001719"
     CDS             complement(6686..7156)
                     /locus_tag="VVO77_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU5693700.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAKNDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(7173..9446)
                     /locus_tag="VVO77_001720"
     CDS             complement(7173..9446)
                     /locus_tag="VVO77_001720"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEU5693701.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSSQDVIREVVYVESRVDTDQKGLPDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            9792..12893
                     /locus_tag="VVO77_001721"
     CDS             9792..12893
                     /locus_tag="VVO77_001721"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEU5693702.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     EIEGIHLKIEEIDLEDKETLDLFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRLAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNSSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQVDD
                     SKKKLDVTLFSDLYRQVDQEVREGAFYYIKGKVQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHDSDQEMSRILDQYKGPIPVIIRYEEEQKTIVSPHHFVAKSDELEAKLNGIVMKT
                     IYR"
     gene            12976..13983
                     /gene="pfkA"
                     /locus_tag="VVO77_001722"
     CDS             12976..13983
                     /gene="pfkA"
                     /locus_tag="VVO77_001722"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEU5693703.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            14042..15547
                     /gene="pyk"
                     /locus_tag="VVO77_001723"
     CDS             14042..15547
                     /gene="pyk"
                     /locus_tag="VVO77_001723"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEU5693704.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
BASE COUNT         4962 a         2606 c         3387 g         4688 t
ORIGIN      
        1 gagtcagtat catataccta cggcaaggtg aagctgacgt ggtttgaaga gattttcgaa
       61 gagtataaaa tattcaggtg acgcatagat atagttaatt gaagctttgt ttgaaatctg
      121 ataaaataat gatattacta agttctaaaa actaaagaaa agggaagata tgattacagg
      181 cgaattaaaa aataaaatcg atcagctgtg ggaaattctt tggacagaag gaaacgcaaa
      241 tcctttaaca aatattgaac agttgactta tctcttattt atgaaagatt tggatagtgt
      301 cgagcttgga cgtgaaagtg atgctgaatt tctagggatt ccttatgagg gagtttttcc
      361 aaaagataaa cctgaatacc gttggtcaac ttttaaaaat ataggagatg ctcaggaagt
      421 ttatcgttta atgactcagg agatttttcc gtttattaaa aatctcaagg gggatacaga
      481 tgatacagcc ttttcacgat atatgcgaga agctattttt caaataaata aacctgctac
      541 gcttcaaaag gcaatttcta tcttagatgt ttttccaact aggggattag atgtagattt
      601 tgataatgac aaacaaagta ttactgatat cggagatatc tatgaatatc tgttatcaaa
      661 attgtcgacc gcaggtaaaa atggacagtt ccgtacacct cgtcacatca tcgatatgat
      721 ggttgagttg atgcaaccga ctatcaaaga tatcatctca gatcccgcta tgggttctgc
      781 tggcttctta gtatctgcta gccgttactt aaagcgtaag aaagatgaat gggaaaccaa
      841 tacagataat atcaatcatt ttcataatca gatgtttcat ggaaatgata cggatacgac
      901 tatgttgaga cttggggcga tgaacatgat gctacatgga gtagaaaatc cacaaatcag
      961 ttaccttgac tcgctgtctc aagataatga agaagccgat aaatatactt tggttttagc
     1021 aaatcctcct tttaagggct cacttgacta caattcaacc tctaatgacc ttcttgcaac
     1081 cgtaaaaacc aaaaaaacag aattactctt tctttctctt ttcttgcgaa ctttaaaacc
     1141 aggtggacga gcagcagtta tcgtacctga tggtgtcctt tttggttcgt ctaaagctca
     1201 taaaggaatt cgtcaggaaa ttgtagagaa tcataagctt gatgctgtaa tctcaatgcc
     1261 tagtggtgtt ttcaagcctt atgctggagt ttcaactgcc attctcatct ttacaaaaac
     1321 tggtaatggt ggtactgaca aagtctggtt ttacgatatg aaagcggatg gtttaagttt
     1381 ggatgataag cgacaaccga ttagcgacaa tgatattcca gatattatcg aacgctttca
     1441 tcatcttgaa aaagaagcag aacgtcagag aacggatcaa tctttctttg ttccagttgc
     1501 tgagataaag gaaaatgatt atgatttgtc tatcaataaa tataaagaga ttgagtatga
     1561 aaaagttgag tatgaaccaa cagaggtcat cttaaagaaa atcaatgatt tagaaaaaga
     1621 aattcaagct ggcttggctg aattagaaaa attactcaag tagggaggtg gctgtatgaa
     1681 aaaagtgaag ttgggggaag tcttatctct aaaaaaaggc aagaaagcca ctgtacttgc
     1741 tgaacaaaca actctaagcc aacgttatat tcaaatagat gatttaagaa ataataataa
     1801 tttaaaattc actgaaagtt taaatatgac tgaagcactc ccagatgata ttctgatagc
     1861 atgggatgga gctaatgcag gaacagttgg ttatggatta tcgggagctg ttggtagtac
     1921 aattacggtc ttaaaaaaga atgagcgata caaagaaaaa attatatcag attacttggg
     1981 agtctttttg gaaagtaaat cgcagtattt acgagaacat tcaacaggtg caacaattcc
     2041 tcatttaaac aagaatatat tacttgattt acaattagaa ttgctaggta tcgaagaaca
     2101 agagaacatt atctgtattc ttaatacgat taaaaggctt attactaaaa gaaaattgca
     2161 gttagatgaa ctaaacttgc tcgtcaaatc ccgatttaac gagatgtttg gggaaaataa
     2221 aatatttgaa agcattgata acttatttga tattatagat ggtgataggg gcaaaaatta
     2281 tcctaaatca gatgagttgt ttagtgagga gtactgttta tttttaaata caaagaatgt
     2341 tactaaaaac ggattttcat tcgatacaaa gcaatttatc actaaaacaa aggataaatt
     2401 acttcgaaaa ggcaaacttg agcgttatga tatagtcttg acaacaagag gtactgttgg
     2461 aaatgtagcg tactacgatg aattaataaa atataaacat ttacgtataa attcaggtat
     2521 ggtaatatta cgtcccaaga caccaaatct aaatcagaaa tttattatcc atgttttaag
     2581 gaataataat tatagtcgag tgatatcagg aagtgctcag cctcagttac caattacaaa
     2641 attaaaaaaa atacttctcc ccctcccccc actagccctc caaaatgagt tcgcagactt
     2701 tgtagtccag gtcgacaaat cacaatttgc ttgtgagata gctataaaag tgtggagaaa
     2761 tagcttgaaa tttagtataa tatagctaaa ctatttattt aaagtgagaa aaaaatggga
     2821 aattttagct ttcttttaaa aaatgacgaa tatgaatctt tttcaaaacc ttgcattgaa
     2881 gctgagaata tgattgctac atcaactgtg gctactgcct ttatggcgcg tcgtgcttta
     2941 gagcaggctg tccattggat atatagtcac gattcatatt tagaagctcc ctatcgtgct
     3001 actctatctt ctttagtatg ggatgatgat tttagggata tcgtagattc tgaactccac
     3061 aagcagatag ttctgttgat tcggtgggga aaccatgctg ctcatggtgg tgaaattaag
     3121 gaacgagaag cgattttagc tttgcatcat ttgtatcagt ttgttaattt tatcgattat
     3181 tgttacagca atgagtttgt ggagcgttat tttgatgaga agtgcttacc actttcagca
     3241 aacatcaaat accgagaaac tccacaatct atgataaagt tacaagacag tttaccagaa
     3301 ctgcctgatt ttcatgaaca gatggctgct cagtccgtag aagttcaaga gacttatact
     3361 gaaaaacgtg agactgcagc gcaacggcaa gatgtgcctt tccatattga tcaattatct
     3421 gaggcagaga caagaaagct ctttattgat atcgatctcc gtttagcagg atggatattt
     3481 gaagaaaact gtcgtgttga gatagccgtt gatggtctca agcacggttc aggaattggt
     3541 tactgtgact atgtacttta tggtaaaaat gggaaaattt tagcgattgt ggaggctaaa
     3601 aaagcctctg tcaatccaga agtaggggaa gtacaggtca aagaatatgc tgaagctttg
     3661 gagaaacata tcggctatca gccaatttgc tttattacaa atgggttgaa gcactatata
     3721 cttgatggtc cgaaccgccg ccagattgca ggcttttact ctcaagaaga attgcaatta
     3781 gtgatggata gacgtcatct tcaaaaaccg cttgaggata tttctagtaa aattagggac
     3841 gatatttccg ggcgtcacta ccaaaaacat gccattgcaa gcgtttgtga agctttctct
     3901 gatcatcgta gacaggcact tttggttatg gcaactgggg cggggaaaac tcgtacagca
     3961 gtttctctag ttgatatctt atcacgtcat aactgggtaa aaaacgttct cttcttagcc
     4021 gatagaactt ccttggttaa gcaagcctat gattcgttta gaaaattact cccagatctt
     4081 tccgtttgta acttcttaga agataaagaa ggagctcaat caagtcgtat ggtcttttca
     4141 acttatccga ccatgattgg agcgattagt ggtcaagaag aagtaaatca acgccctttt
     4201 actgttgggc attttgacct tatcataatt gacgaatctc accgttctat ttatcagaaa
     4261 tacaagtcca tttttgatta ttttgatgca aggattgtag gcttaacagc tactccgcgt
     4321 caagatttag ataaaaacac ctatggattc tttaatttgg agaatggggt tccaacatat
     4381 gcatatgatt tggaagaggc tgttaaagac ggatatttag tagcctatca ttctatcgaa
     4441 accaaactga agctacctac ggatggtcta cattatgatg atttgtccga agaagaaaag
     4501 gaacattttg atagcaaatt tgaagacgat agctgtgaaa aagatattga tgggagtgtg
     4561 tttaattcct ttattttcaa taaaagtaca gtagaaattg ttttaaatga actcatgaca
     4621 agaggaattc agacagcctc gggtgatgaa attggtaaaa ctattatttt tgctaaaaat
     4681 catgaccatg cggaatatat cagaggtatt tttaacaacc gctatcctga aaaagggagc
     4741 gactatgctc aggtgattga ttatagtatt aagcattatc agaccttgat tgatgatttt
     4801 aaaattaagg agaagtatcc tcaaattgcg atttctgtcg atatgttaga tacaggtatt
     4861 gatgtaccag aggttgttaa tttagtcttc ttcaagaaag tacgctctaa aactaagttt
     4921 tggcagatga ttggtcgagg aacccgtcta tgtaaagatt tatttggacc tgagcaggat
     4981 aagaaaaact tcttggtatt tgattatggg gacaattttg attattttcg tgcagatcca
     5041 agagatggag agggtcgtca cattgtttcg ctgactcagc gtttatttaa tatcaaagtg
     5101 gacttgattc gagaacttca gggactccaa taccaagaag atcagtttgc gagagcatac
     5161 cgtcagcagc ttgtctcgga acttcaaggt cgtatagaga gcttaaatga gttggacttc
     5221 agggttcgta tggttttaga tacagtttat agctatagga aattggaaag ttggcagaat
     5281 ctaactgctg ttacaagtga aaccattcaa aaaaatctct ctccgctttt atttgatgaa
     5341 gataaagaag atgagatggc gaggagattt gatttgtggt tgcttcatat tcagttgggg
     5401 caactgacag ctaaatcttc cactgttcat atttcccaag tgatgaagac ggctagagct
     5461 ctttctgcta ttggcaatat cccgcaggtt tttgagcagg ctgaaattat cagggaagta
     5521 caggagcctg aattttggaa agaagttaac ttgtctgatt tggaaaaaat tcgtcttgct
     5581 attcgagatt tattacagtt tttggataaa acagaccgta aaccctacta tgttaacttt
     5641 gaagatcgta tactctccac tgttcacgag accacagcat ttttgcaggt caacgatctt
     5701 cggtcttaca atgaaaaagt tgacatctga tgatatgctt gcacttgaaa aattgctttg
     5761 ggaaaaatta ggtagtaaag cagactacca aagtcattat gaaaataagg caattccgag
     5821 attggttcgt gagattattg gcttagatag agagtctgcc aatcgtattt tttctaaatt
     5881 tttgtcggat gagaatctta atgccaggca gatttcattt gtaaaattga ttgtagacta
     5941 cattgtagaa aatggttttt tagagacgaa agtgttaacg caagagccgt ttaaatctta
     6001 tggttctgtt caactactct tccaacacca actaccagta cttcgtaata ttgttcaaat
     6061 cattgaactt atcaataatc gagctggaga agcggcttaa attctaaagt gattgccatg
     6121 ctgagactca tttaaaatta aaaagagtag aaatttatga tatatatgag aagttttatt
     6181 aggaagaatg tcatcgtttt tctagaatac agtatcagtt gttaagtggc tgataaattt
     6241 caaagtagat acttgtacca cgatgtttgt tgatcgagtt attaacaaaa gagctacttt
     6301 gattttaaag aaatagaaaa caaaaagccg agcaagaatt caattgcagg agaaaatgaa
     6361 ataatactca atgaaaatca aagagcaaac taggaaacta gctgcaggct gctcaaaaca
     6421 ctgttttgag gttgtagata agactgacga agtcagctca aaacatggtt ttgaggttgt
     6481 agatgaaact gacgaagtca gtaaccatac ctacggcaag gcgacgttga cgcggattga
     6541 agagattttc gaagagtata aatcttccta ggataaagca aaacgcatag tatcaagggt
     6601 tttcaacact tgatactatg cgttttctga tgttaaagac tttctaccag tttttttaag
     6661 cataattgtt agttgtagtc atttattatt cttcaaagaa aaatggtggg gcgaattttt
     6721 tcagttcttc aaagcacttt tgagcagtat ctgcatcttc acagatgata agacagacat
     6781 cattaccaca aagggtagcg atagcgtcag ggaagctcaa agtatcaatg atagaaccaa
     6841 aggattgagc cagtccagga agggttttta gtaggacttg gtgttgaact gggcgcatcc
     6901 agacaagggc gtcttccatg tagagttcga gacgtttttc ccattttgag atggaaccat
     6961 tgttaagaac ataataagcg ctatcttctt cgcggacttt tgataggttc atatttttga
     7021 tgtcgcgtga gagggttgcc tgggttactt gaatgtcgtt cttagcaaga agggcttgca
     7081 actcagcctg tgtatgaatc ttgttttttg tgataagagc gcgtataagt tggtggcggt
     7141 gttctgattt attcataata atgtaactcc ttttagcaag gtaaggtaag catggactga
     7201 gcgaggtcga cagtcaagtg gtagtctgta ttgtcacgga tggtgatttc aaagtcagta
     7261 gtatagagga ctaaacggag agtgtctcct tcttttagct tgtaaatagt tggctgcagt
     7321 tcaaattgaa cgtccatcca ttcatctgca gtaatatcct ctactaacag taaatcattt
     7381 ctattttgta aattaaggta accttttgtc acgactcgtt gtgcctctgg tctaaatggc
     7441 aattcacaga gattttccaa catgtgatag cgaccgttgt caatggttct agcacttaaa
     7501 atagctggat aaggttgtag gtatttcttt tgcccaaatt ctagcagttg ggcagataag
     7561 agccccttgt ttgtactgga tttgatacga agattgagct gagcgcgacc atttaggtgg
     7621 agatctttag tcacaggaag gttaatagta atctgattgg ctttcccttg atagagctct
     7681 gtattgaagg tttggtatgt cttaccatag cgctcaaaat ccttatctgg gtactggttt
     7741 tgaatagctt gctcttcttg accaagtgag aaggtttcac agttttcttg cccaccgaag
     7801 ttatcaagtg ataaccaagt ctgtggagct gtattgtcct gccagataac agtaggaagt
     7861 tgaaagtctg tttcctgtcc tagtaatttc ttggtcaata aggcatttat ggactcacgg
     7921 aagtcaattg attgccaatt gttcatgtaa acatgagcac cattatggaa aaagagatgc
     7981 ttgtgtatat gagtaggaag agcatggaac atctggtaaa catgaagtgg tttgacattc
     8041 caatcctgag aaccatgagt aaagacaacc tctgccttta ctttatgggc attgagcaga
     8101 taattgcggt catgccaaaa ctgattgtag tccccagttt ttcgatctag ctgagctttc
     8161 actttttcta agtcagcttg gtgagcttca ttgccacgga tatagtcgcc agctaagaga
     8221 ttacgagaat aggttaactc agcaagggag tcaaagtcct cacctggata accacctggg
     8281 ctagtcacca gaccgttttc acggtagtag ttgtaccatg atgaaattcc tgcctcggca
     8341 atgataactt ctaaaccatc gactcctgta gtcgcaagac cattggacat ggtacctaga
     8401 taggaaagtc ctgttgtagc aacttttccg tttgaccaat cagccttgac ttgacgctgg
     8461 cgcgtgtgat cagtaaaggc acggcaacgg ccgttaagcc aatcgatgac atttttataa
     8521 gcctcgattt gctggtagtc tccattagtc atgaaacctg tcgagtcttt ggtaccaaca
     8581 cctgagacat agagattggc aaagcctctc ggaaggaagt agtcgtttag tgtatagcta
     8641 gagttgatgt gagttagctt ttcctcagcc tctgctataa gctcagcttt accttggggt
     8701 tggacgagat ttagttgagg tttctctagc tcaatcttgt gaggaagctt aacctcaagc
     8761 tcgccctcca tcttgtagag agccttgtca ctagccttgt cattggttcc ctgatgataa
     8821 gggctggctg tcatgatggc agggattttt ccatcaaaac gagggcgaat aatgctaacc
     8881 tttactaggt ctggtagccc tttttggtca gtatcgacac gagactcaac gtaaacgact
     8941 tcacgaatga catcctggct agaaaaagta gccaaactct tgccgttaaa gtagtggtag
     9001 tcattatcct ccggaataag accatcacta acaagttggt cgataagagt atttcctttt
     9061 ttggtgcgag tatttagtaa ctgatagaga ttttcaatca agtcaccata tataatggga
     9121 aatccagttt ctttacgaaa aacgtcacta tcttcgaagt caaccaaata agaaaagcct
     9181 aaaagttgaa aagcaacagt ataaaaaata tctgctgtca gttcatcttc tgattgaaaa
     9241 aatgtcagca ggtctgtttt tttatcagct gctaggatag aaagtgggta gttggtgtct
     9301 tgataagtga aaaagaaacg acgtaaaaag gtttcaagtg agtctttgtg attggctgta
     9361 ttttgtaaat caaagccaca tttttttagt tcagataaga cattttcttt tggaaaattg
     9421 atataactat attgattaaa acgcatagaa cctccatata gaatgacagt taaggttatt
     9481 atatcaaaaa aaaagcagaa agggaattgt taacttcaaa aggaaataat ccaataaaaa
     9541 tgaataaagt actaaattca atatagagaa cagagtaaca ataagaataa tagatagggt
     9601 ataaaagttc taggagattt atattatatg ctttctattt ttatacacaa tatagtataa
     9661 atataaaaat gatgacaaaa atacaaatga atagaaaata aattagtaag ctgatgaaat
     9721 ttttctcaag agaagccatt tataggtgaa aatggtataa tatagtgaga aggatagagg
     9781 agaagtgtaa attgatcgca caactagata caaaaacagt ctatagtttt atggaaagcg
     9841 tcatttcgat cgaaaagtat gtgagagcag ctaaagaata cggctacact catttggcta
     9901 tgatggatat tgacaatctt tatggcgctt tcgactttct agagattaca aaaaaatacg
     9961 gcattcatcc tttgctaggg cttgaaatga cagtgtttgt agatgatcag gaagtgaatt
    10021 tgcgtttttt agctctatct agtgtgggct atcagcagtt gatgaagctt tcgacagcca
    10081 agatgcaggg ggagaaaact tggtcagtcc tgtcccagta cctggaggat atcgcggtca
    10141 ttgtgcctta ttttgataga gttgagtcgt tagaactagg ctgtgattac tatatagggg
    10201 tttatccaga aacactagca agcgaatttc atcatcctat cttacctctt tatcgggtca
    10261 acgcttttga aagcagggat agagaagttc ttcaagtttt aacagcgatt aaagaaaatc
    10321 taccgctcag agaagttccc ttgcgttcga gacaagatgt ctttatatca gcaagttctt
    10381 tagagaaact attccaagag cgttttccgc aagctttgga caatttagaa aagcttattt
    10441 caggcatttc ttacgacttg gatactagtc tgaaactgcc tcgttttaat ccagctagac
    10501 cagcagtaga ggagttgaga gagcgtgctg aactggggct tgttcagaag gggttgacta
    10561 gtaaagaata tcaagataga ctagaccaag aattgtctgt tattcatgat atgggctttg
    10621 atgattattt cttggttgtt tgggatttgt tgcgttttgg acgatcgaat ggctattata
    10681 tgggaatggg aaggggttct gcagtaggca gtttggtttc ttatgcctta gacatcacgg
    10741 ggattgaccc agtagagaaa aatctgattt ttgaacgctt tcttaatcgt gaacgctata
    10801 ccatgcctga tattgatatt gatattccag atatttatcg tccagatttt atcagatatg
    10861 ttggtaataa atatggtagt aaacatgcgg cacaaatcgt tactttttca acctttggag
    10921 ccaagcaagc tcttcgagat gtcttgaaac gctttggtgt gccagagtat gaattatctg
    10981 caattactaa gaaaatcagt tttcgtgaca atcttaagtc ggcctatgag ggcaatctcc
    11041 agtttcgtca gcaaatcaat agtaagttag aataccaaaa agcttttgag attgcttgca
    11101 agatagaggg ctatccaagg caaacctctg tccatgcggc tggtgttgta attagtgacc
    11161 aagatttaac caactatatt cctctaaagt atggtgatga aattccactg actcagtatg
    11221 atgctcatgg agttgaggct agcggacttt tgaagatgga ctttctggga ctacgaaatt
    11281 tgacctttgt ccagaagatg caagagttgc ttgctgaaat agaaggtatt caccttaaaa
    11341 ttgaagaaat agatttggaa gacaaagaaa cgttagattt atttgcctct ggaaatacaa
    11401 aaggtatctt tcaatttgag caaccaggtg ccattcgtct gcttaagcgt gtgcaaccag
    11461 tctgttttga agatgtcgtc gcgactactt ctctaaatcg accgggtgct agtgactata
    11521 tcaataattt tgtggcaaga aagcatgggc aggaagaagt gactgttctg gatccagtac
    11581 tggaggatat tttggctcca acctacggca taatgctcta tcaggagcag gttatgcagg
    11641 ttgcccagcg acttgccgga tttagtcttg ggaaagccga tattttgcgt cgggctatgg
    11701 ggaaaaagga tgcctctgcc atgcatgaga tgagggcttc ctttattcaa ggttcattag
    11761 aagctggtca tactgtggaa aaagcagagc aggtctttga tgttatggag aagtttgcag
    11821 gttatggttt taacaggtca cacgcctatg cctactcagc cttggccttc cagttggctt
    11881 atttcaaaac gcattatcca gccatttttt atcaggtcat gttaaattct tccaacagtg
    11941 attacttaat agatgcactt gaagcaggtt ttgaagtagc ctctctatcc atcaacacca
    12001 ttccctatca cgataaaatt gccaacaagg ccatctatct aggtttgaaa tccattaaag
    12061 gagtcagtaa tgatttagct ctctggatta ttgaaaatag accttattct aacattgaag
    12121 attttatagc taaattacct gagaattatc tgaaacttcc tctgctagaa cctttggtaa
    12181 aagttggtct tttcgattca tttgaaaaaa atcgtcaaaa agtatttaat aacttagcta
    12241 atctatttga atttgtgaaa gagttgggaa gtttgtttgg agatgctatt tatagttggc
    12301 aggaatcgga agattggacg gaacaagaaa aattttatat ggaacaagag cttttaggga
    12361 taggtgtcag caaacatcca ctacaagcta ttgcaagtaa ggctatttac ccgattaccc
    12421 caattggaaa tttgtcagaa aatagctatg ctattatctt ggttgaagtt cagaagataa
    12481 aagtaattcg taccaaaaag ggtgaaaata tggctttctt acaggtggat gacagtaaga
    12541 aaaaattgga tgttacactc ttctcagatt tatatcgaca ggttgatcag gaagtaagag
    12601 aaggagcatt ctactatatc aaagggaaag tccagtcacg tgacggtcgt ctgcaaatga
    12661 ttgcacaaga aataagagaa gcagtggctg agcgcttttg gattcaggtt aaaaatcatg
    12721 actcggatca agagatgtca cgtattttag accagtataa aggcccaatc ccagtcatca
    12781 tccggtatga agaggaacag aaaaccatcg tttctcccca tcattttgta gctaaatctg
    12841 atgaattaga ggcgaaattg aatggaatag ttatgaaaac gatttatcgc taaaaatacg
    12901 gaaaatagaa gaattttaaa atcaaatgtg atataatcaa gaagaatgtt aaaagaaaaa
    12961 ggagcataaa ccaatatgaa acgtattgct gttttgacta gtggtggaga cgcacctggt
    13021 atgaacgctg ctatccgtgc agttgttcgt caagcaattt cagaaggaat ggaagtgttt
    13081 ggtatctatg acggatatgc tggtatggtt gccggtgaaa ttcaccccct agatgcagct
    13141 tcagtaggag acatcatttc tcgtggtggt acttttcttc actcagctcg ttatccagag
    13201 ttcgctcaac ttgaagggca acttaaaggg attgagcaat tgaaaaaaca cggaattgaa
    13261 ggtgtagttg ttatcggtgg tgacggatct taccacggcg ctatgcgttt gactgaacat
    13321 ggcttcccag ctattggtct tccaggtaca atcgataacg atatcgttgg tactgacttt
    13381 acaatcggtt ttgacacagc ggttactact gccatggacg ctatcgataa gattcgtgat
    13441 acatcatcaa gtcaccgtcg tacttttgta atcgaagtta tgggacgtaa cgctggtgat
    13501 atcgctcttt gggctggtat tgcaactggt gctgatgaaa tcatcatccc tgaagcaggc
    13561 ttcaagatgg aagatatcgt agcaagcatc aaagctggtt atgaatgtgg taaaaaacac
    13621 aatatcatcg tcttagctga aggtgtgatg tcagcggctg aatttggtca aaaacttaaa
    13681 gaagctggag atacaagcga ccttcgtgta acagaacttg gacatattca acgtggtggt
    13741 tctccaactg cgcgtgaccg tgttttggcg tcacgtatgg gtgcacatgc tgttaaactt
    13801 cttaaagaag gtatcggtgg tgttgcggtt ggtattcgta acgaaaaaat ggttgaaaat
    13861 ccaattcttg gtactgcaga agaaggggca ttgtttagcc ttactgcaga aggtaagatt
    13921 gtggttaaca acccacacaa agccgatatt gagctatcta gcttgaataa gagcttgtca
    13981 taatttacaa tttagttaat aagaccaaaa aggtcatata tataaaggag tcacaaaaat
    14041 catgaacaaa cgtgtaaaga tcgttgcaac tttgggtcct gcggtagaaa tccgtggtgg
    14101 taaaaaattc ggtgaggatg gatactgggg tgaaaaactt gatgttgaag cttcagctaa
    14161 aaacattgct aaattgattg aagctggtgc taacacattc cgattcaact tctcacacgg
    14221 cgaccaccaa gaacaaggtg agcgtatggc aactgttaaa cttgcggaaa aaattgcagg
    14281 taaaaaagtt ggtttccttc ttgatacaaa aggacctgaa atccgtacag aattgttcga
    14341 aggtgaagct aaagaatatt catacaaaac tggtgaaaaa attcgtgttg caactaaaca
    14401 aggaatcaaa tcaactcgtg aagtgattgc gttgaacgtt gctggtgctc ttgatatcta
    14461 tgatgatgtt gaagttggtc gtcaagtttt ggttgacgat ggtaaacttg gtcttcgtgt
    14521 ggttgctaaa gatgatgcaa ctcgtgaatt tgaagttgaa gttgaaaacg atggtatcat
    14581 cgctaaacaa aaaggtgtga acatccctaa cactaaaatt cctttcccag ctcttgctga
    14641 acgcgataac gacgatatcc gtttcggtct tgaacaaggt atcaacttca tcgcaatttc
    14701 attcgtacgt actgcaaaag atgtgaacga agttcgtgca atctgtgaag aaactggaaa
    14761 cggacatgtt caattgttcg ctaaaatcga aaaccaacaa ggtatcgata acttagacga
    14821 aatcatcgaa gcagctgatg gtattatgat tgctcgtggt gatatgggta tcgaagtacc
    14881 gttcgaaatg gttccagttt atcaaaaaat gattatcaag aaagtcaatg ctgcaggtaa
    14941 agttgttatc actgcaacaa acatgcttga aacaatgact gaaaaaccac gtgcaactcg
    15001 ttcagaagta tcagacgtat tcaacgctgt tatcgacgga actgacgcta caatgctgtc
    15061 aggcgagtct gcaaacggta aatacccact cgagtcagta actacaatgg ctacaatcga
    15121 caagaacgct caagctcttc ttaatgaata cggacgtctt gattcagatt catttgagcg
    15181 taactctaag acagaagtaa tggcttctgc tgttaaagat gctactagct caatggatat
    15241 caaattggtt gtaactctta ctaagacagg tcatactgca cgtttgattt ctaaataccg
    15301 tccaaatgct gacatcttag cattgacatt tgacgaattg acagaacgtg gcttgatgtt
    15361 gaactggggt gttattccaa tgttgacaga tgctccatct tcaactgacg atatgttcga
    15421 aatcgctgaa cgtaaagcgg tagaagcagg tctcgttgag tcaggcgatg atatcgttat
    15481 cgttgctggt gtgccagtag gagaagctgt tcgcacaaac acaatgcgta tccgcacagt
    15541 acgttaagaa aaatataaaa acctatcata tccagcttta gagcttgtgt gataggcttt
    15601 ttgtatagag ggtaagaaat aggcaaaact ttcataatgg att
//
LOCUS       DAVHLA010000046        15278 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVHLA010000046 DAVHLA010000000
VERSION     DAVHLA010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15278)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15278)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15278
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.046"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            83..880
                     /locus_tag="VVO77_001724"
     CDS             83..880
                     /locus_tag="VVO77_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEU5693705.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLIHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            1028..2287
                     /locus_tag="VVO77_001725"
                     /pseudo
     CDS             1028..2287
                     /locus_tag="VVO77_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604466.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
     gene            2383..3657
                     /locus_tag="VVO77_001726"
     CDS             2383..3657
                     /locus_tag="VVO77_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEU5693706.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMKQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHEALLAKDKEV
                     QLLENQLATLRLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3667..4545
                     /gene="truB"
                     /locus_tag="VVO77_001727"
     CDS             3667..4545
                     /gene="truB"
                     /locus_tag="VVO77_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEU5693707.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVIAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4786..5088
                     /locus_tag="VVO77_001728"
     CDS             4786..5088
                     /locus_tag="VVO77_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEU5693708.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKHQS
                     VMADLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5196..5834
                     /gene="udk"
                     /locus_tag="VVO77_001729"
     CDS             5196..5834
                     /gene="udk"
                     /locus_tag="VVO77_001729"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEU5693709.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5962..7302
                     /locus_tag="VVO77_001730"
     CDS             5962..7302
                     /locus_tag="VVO77_001730"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEU5693710.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLTHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7280..7492
                     /locus_tag="VVO77_001731"
     CDS             7280..7492
                     /locus_tag="VVO77_001731"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEU5693711.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7489..8364
                     /locus_tag="VVO77_001732"
     CDS             7489..8364
                     /locus_tag="VVO77_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEU5693712.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVAIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQVPFE
                     TESIVSVVESLRING"
     gene            8357..9172
                     /locus_tag="VVO77_001733"
     CDS             8357..9172
                     /locus_tag="VVO77_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEU5693713.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            9165..9596
                     /locus_tag="VVO77_001734"
     CDS             9165..9596
                     /locus_tag="VVO77_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU5693714.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIDTFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9603..11270
                     /gene="recN"
                     /locus_tag="VVO77_001735"
     CDS             9603..11270
                     /gene="recN"
                     /locus_tag="VVO77_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEU5693715.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQYGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDMTEAALTQARELLRNREK"
     gene            11272..12000
                     /locus_tag="VVO77_001736"
     CDS             11272..12000
                     /locus_tag="VVO77_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEU5693716.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12079..13902
                     /gene="lepA"
                     /locus_tag="VVO77_001737"
     CDS             12079..13902
                     /gene="lepA"
                     /locus_tag="VVO77_001737"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEU5693717.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(14106..14186)
                     /locus_tag="VVO77_001738"
                     /pseudo
     CDS             complement(14106..14186)
                     /locus_tag="VVO77_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            14359..14835
                     /locus_tag="VVO77_001739"
     CDS             14359..14835
                     /locus_tag="VVO77_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU5693718.1"
                     /translation="MVLDYFFDKNLVLCLEADNQEQLFDQVASLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMNFFTGNGHLEDLSKISEPEKLYAYIDEAIA"
     gene            14873..15175
                     /locus_tag="VVO77_001740"
     CDS             14873..15175
                     /locus_tag="VVO77_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU5693719.1"
                     /translation="MIKILAACGAGVNSSHQIKSTLEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFCIPAMSAPVFDNIRLPAKQNMV"
     gene            15183..>15278
                     /locus_tag="VVO77_001741"
     CDS             15183..>15278
                     /locus_tag="VVO77_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HEU5693720.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEMLAVL"
BASE COUNT         4568 a         2768 c         3574 g         4368 t
ORIGIN      
        1 acttttatga aatacagaaa acgcttccta aaacctaaag tttgtgatat aattatcaag
       61 aaaaaagatt taggagttta ttatggtttc ttcagaattt atctcaaaga ttgaatttgc
      121 ttgcaataag aaagaaagtc tttatagtca aagcaaattt aagtatgcga ttcgttcgat
      181 gttcgcaggt gcatttttaa ccttcagtac tgctgcaggt gcagttgggg ctgacttgat
      241 taataaaatt gcaccaggta gtggacgctt cctctttcca ttcgtttttg cttggggctt
      301 ggcctacatt gtttttttga atgccgagtt ggtcacttca aacatgatgt tcttgactgc
      361 tggtagtttc ttaaaaaaaa tctcttggag aaaaacagct gagattttac tatactgtac
      421 cttgttcaac cttatcggag ccttgatagc agggtggggc tttgctcatt cggcagccta
      481 tgcgaatctg atacacgata gtttcatctc aggtgttgtt gagatgaagt taggccgctc
      541 aaatgaattg gtcttgcttg aggcgatttt ggcaaatatt ttcgtaaata ttgcgattct
      601 gtcatttatt ttggtcaaag atggtggtgc caaactttgg cttgtgttgt cagctattta
      661 catgtttgta ttcttaacaa acgagcacat tgcggcgaac tttgcttctt tcgcgattgt
      721 gaaattcagt gttgctgcgg attcaattgc caacttcggt gttggaaata tgcttcgcca
      781 ctggggtgtg actttcatcg gaaactttat cggaggaggc ctcttgatgg gtcttccata
      841 tgccttcctc aataaaaacg aagatactta tgtagattaa gaaaatgagc acgattgagt
      901 cgtgcttttt tcattttcaa aataaggtaa tagctatttc ttatatcaaa atatagaaaa
      961 ctgatatttg taaactataa ctcaaggtgc tacaatatcc ttaataaaat gatatggagg
     1021 tcaccttatg acttgtgatt ttaaatctga aactctacaa ctacatgctg gtcaagttgt
     1081 ggctccagct actaagtctc gtgcagtgcc gatttatcaa acaacatttt ttgtttttga
     1141 tgacacgtag gaaggtgccg atctgtttgc cttgaggaaa ccagggaaca tttatactcg
     1201 tatcaccaat cctacaacag ctgcccttga aggtggtgtt gaagcgctag caacagcatc
     1261 aggtatgact gcagtgactt atacgatttt ggcgcttgcc catgctggtg accatgtagt
     1321 ggctgcttcg actatttacg gtggaacctt caatcttttg aaagaacccc ttcctcgtta
     1381 tggtatcaca acaacctttg tcgatgttga taatttggag gaagtagaag cagctatcaa
     1441 agacaatacc aaacttgtct tgattgaaac cttgggtaac tccttgatta atattccaga
     1501 cctggaaaaa ctggcagaga ttgctcataa acatcaaatc ccacttgtgt cagacaatac
     1561 ttttgcaata ccttatttga ttaacgtctt ctctcatggc gttgacattg ccattcactc
     1621 tgcgactaag tttatcggtg ggcatggtac aactattgga ggaataattg tcgatagtgg
     1681 tcgttttgac tggatggctt cagggaaatt ccctcaattt gttgacgagg gttcaagctg
     1741 ccacaatttg agctatactc gtgatgtggg tgcagtagcc tttattatag ttgttcgagt
     1801 tcaattgctt cgtgatacag gtgcagcctt gtcaccattc aatgctttcc tcttgctaca
     1861 aagacttgaa accctttcac ttcgtgtgga acgccatgta caaaatgctg agacaattgt
     1921 tgattttctt gtcaaccatc ctaaggtaga aaaggtaaat tatccaaaac ttgcagatag
     1981 tccttattat gccttggctg agaaatactt gccaaaaggt gtcggttcaa tctttacctt
     2041 ccacgtcaaa ggtgacgagg aagaagcacg caaggtcatt gatcatttag aaatcttttc
     2101 tgaccttgca aacgcggcag atgctaaatc gcttgttgtc catccagcaa caatcactca
     2161 cggtcaattg tcagaaaaag acctagaagc agcaggtgtc acaccaaatc aaatccactt
     2221 gtctatcggt cttgaaaatg tagaagattt gattgaagac ttacgcttgg ccttggaaaa
     2281 aatttaaagt aaaagaagat aaacagtggg ttttgactca ctgtttttga ttttccttca
     2341 tgcatgatat aatggttaca gaagtctaga aagaggaacg atatgaacga aatcaaatgt
     2401 cccaactgtg gggaagtctt tacagtaaat gagagtcagt atgccgaact cttgtcccaa
     2461 gtgagaacgg cagagtttga taaggaacta cacgatagga tgaagcagga actggccttg
     2521 gcggagcaaa aggccatgaa tgagcaacag actaaactgg ctcagaagga tcaagaaatt
     2581 gcgcaattac agagtcagat ccaaaacttt gatacagaaa aagaattggc caagaaagag
     2641 gttgaacaga caagccatga ggctctcttg gctaaggaca aggaagtaca gctcttagaa
     2701 aatcagttgg ctaccttgcg tttggagcat gaaaatcaac tacaaaagac cctttctgac
     2761 ctagaaaaag aacgggatca ggttaaaaac caactacttt tgcaggaaaa ggaaaatgaa
     2821 ttatctttgg cttctgttaa gcaaaactac gaagcccagc tcaaggcagc tagtgaacaa
     2881 gtcgagtttt ataagaattt taaggctcaa caatctacaa aagcgattgg ggaaagccta
     2941 gaacagtatg cagagagtga gtttaacaag gttcgtagtt tcgcctttcc aaatgcttac
     3001 tttgagaagg ataacaaggt ctcttcgcgt gggtctaaag gggactttat cttccgtgag
     3061 tgtgatgaaa atggagttga aatcatttct atcatgtttg agatgaaaaa cgaagcagac
     3121 ggaacagaga agaagcacaa gaatgcagat ttttacaagg aattggacaa ggaccgtcgg
     3181 gagaagaact gtgagtatgc cgttttggtg accatgcttg aggctgataa tgactacttt
     3241 aacacaggga ttgttgacgt cagtcacgag tatgaaaaaa tgtatgttgt tcgtcctcaa
     3301 ttctttatcc aattgattgg tctcttacgt aatgcggcgc taaattccct aaaatacaag
     3361 caggagttgg ccttggttcg cgagcaaaat attgacatta cgcattttga ggaagatttg
     3421 gatgccttta agctagcttt tgctaagaac tataattcag cttcgactaa ctttggaaaa
     3481 gctattgatg aaatcgacaa ggccatcaaa cgcatggaag aggttaagaa attcctgact
     3541 acatctgaaa accaactccg tctagctaac aacaaattgg aagatgtctc tgttaaaaaa
     3601 ttgacccgga aaaatccaac aatgaaagcg aagttcgaag cactgaaggg ggagtagaaa
     3661 gcaaaaatga acggtattat caacttaaaa aaagaagcag gaatgacctc gcatgatgcg
     3721 gtttttaaac tgcgtaagat tttgggaacc aagaaaattg gtcatggtgg aaccttggat
     3781 ccggatgtgg tgggtgtttt gccgattgcg gttggcaagg cgacacgcat ggtcgagttt
     3841 atgcaggacg agggtaagat ctatgagggg gaaattactc tgggttattc cacgacgact
     3901 gaggatgcta gtggggaagt gatcgcagaa acccctgttt tgtctccctt ggatgaaaag
     3961 cttgttgatg aagcgattgc tagcttgact gggcctatta cccagattcc ccctatgtat
     4021 tcggcagtta aggttaatgg tcgcaagctc tatgagtatg cgcgtgctgg tcaggaagtg
     4081 gagcgtccag aacgtcaggt gaccatttat caatttgagc gaacaagtcc gatttcttat
     4141 gatggccaac ttgctcgatt cacttttcgt gtaaaatgca gtaaagggac ttacatccgt
     4201 actttgtcag ttgatttggg tgaaaagctt ggttatgcgg ctcatatgtc ccatttgact
     4261 cgtactagtg ctgctggctt acaattagaa gacgctcttg ccttggagga aattgctgaa
     4321 aaagtagagg ctgggcaatt agattttctc catcctttag agattgggac aggtgacctt
     4381 gtcaaagttt tcctaactcc agaagaggct acagaagttc gctttggtcg ttttattgag
     4441 ctagaccaaa cggacaaaga actggctgcc tttgaagatg ataaattgtt agccattcta
     4501 gaaaaacggg gcaatctcta taagccaagg aaggttttta gctagatcgt ttaggaataa
     4561 aaatcgggtg atagataaca attgcttgat aaaaccccat actaatagta gaatggtttt
     4621 gggaattata atattccaat tgttgcgagt tgtaggtact caaataatct atatagaaat
     4681 ttagaggtgt gaaatgaagc aatttaaaat tctttcagat aaatatttag agtccattac
     4741 aggttctggt gggaacttag gcccaggatt tggtgtgata attccatgat gcgaaatgag
     4801 tttcgagaaa gggtggagca acttcttcaa caaaaagaaa taaatgaaaa tagtgagttg
     4861 agtcacctgt ttcgtcttgc tatacaaaat ttagacagaa atgaaaaaca ccaatcggtc
     4921 atggccgatt tgagtcaagg gttgtcactt tacctcatga cgcatcatta ccaggcacct
     4981 aagtctgtca ttgattttgg tttatggatt gccaaagctc ctagccagga aagagggaga
     5041 ctggctttct tgcagatgct tgctcaaacc ctacagggct ttcgttaaaa ctgtcgaaca
     5101 tcagagggaa gactctggtg ttttttgctg atgagactat aaattttgta aaaaatgtga
     5161 tagaatagac gacggataaa ataacggagg atagcatgca aaatagacca atcattattg
     5221 gagtgacagg tggttctggt ggtggtaaaa ccagtgtttc aagagccatt ttatcgcatt
     5281 ttcctgatga aaagatttcc atgattgagc atgattcata ctacaaggat cagtctcatt
     5341 tgacctttga agagcgtgtc aaaaccaact atgaccatcc ttttgccttt gatacagact
     5401 tgatgatcga gcagattaag gaattgttgg cagggcgtcc ggtggacatc ccgacctacg
     5461 actatacaga gcatacacgg agtagcaaga cctatcgtca ggagcctcaa gatgtcttta
     5521 tcgttgaggg cattttggtc ttggaggaca agcgtctgcg cgatttgatg gatatcaaga
     5581 tttttgtgga tacggatgac gatgtgcgta ttattcgtcg tatcaagcgt gatatggagg
     5641 aacgtggccg tagccttgat agcgttatta accagtactt aggtgtggtc aaaccaatgt
     5701 accaccagtt tatcgagtca actaagcgtt atgctgatat cgtcattcct gaaggggtta
     5761 gcaataccgt ggctatcgac ctgttgacga ccaagattgc aaagattttg gaagaagctc
     5821 gaaacagcaa ataatcacat gtggaggcct tgcctccttt ttctattttt ccctcataat
     5881 ggtacataaa tggagatttt taggcatatt tttggtataa taatacccat aaaagagcaa
     5941 gtaaatgaat agtaggtgga gatggaaaag tatttatcgg taacaacttt gaccaaatat
     6001 ctgaaaatga aattcgataa agacccatac ttggaacggg tctatttaac tggtcaagtt
     6061 tccaactttc gtaaacgacc tactcaccaa tatttctccc taaaggatga ccatgcagtt
     6121 attcaagcga ccatctggtc tgggatttat cagaaattag ggtttgacct ggaagaagga
     6181 atgaagatca atgtgattgg gcgtgtacag gtctatgaac caagtggtag ctactccatc
     6241 atcattgaaa aagctgagcc tgatggggtt ggggcgcttg cgattcagtt tgaacaactt
     6301 aagaaaaaat tgacagaaga aggcctgttt caagaacgct tcaagcaagc tctaccccaa
     6361 ttttctaaga gaattggggt agtaaccagc cgtagtggag ccgttattcg agatattatc
     6421 acgaccgtca gcaggcgatt cccaggtgtt gacatccttc tttatcctac caaggttcaa
     6481 ggtgaagggg ctgcggagga aattgctaga aatattgcgc gtgctaatca acgggacgat
     6541 ttggatttgc tcattattgg tcgtggaggt ggttctattg aggatctctg ggcctttaac
     6601 gaagaaattg tggtacgagc tatttttgaa tctcgtttgc cagttatctc tagtgtgggg
     6661 catgagacgg atgtgacctt ggcagatttt gtggcagatc gacgcgctgc aacgccaaca
     6721 gcggcggctg aactggcaac acctgtgacc aagttggatg tattaactca tttgcaaaat
     6781 caggaaaaac ggatggcaac ggcagtccga aatgttctat ctaagaaaca agaggctttg
     6841 aaaaaatgca gtcagtctgt tatctttaga caacctgagc gcttgtatga cggttatttg
     6901 caacgcttgg accaactgca actgcgtttg aaacaaagtt tgcgaactcg gatttctgat
     6961 aacaaacaat tagttcaagc aagaactcat caattagtac aattatcacc tgttaccaaa
     7021 atccaacgct atcaagaccg tttaggacag ttggacaagc tcttaggtag ccaaatggcg
     7081 ttagtttatg acgccaaggt tgctgaggcc aagcgacttt cggaagcttt gctcatgttg
     7141 gatactagcc gaatcgtggc gcgtggttat gctattgtca aaaaagaaga gtccgttgta
     7201 gattcggttg agagtttgaa gaaaaaagat caagtaacgc ttttgatgcg agatggtcaa
     7261 gtagaattag aggttaaaga tgtcaaaaca aaagaaattt gaggaaaatc tagcagaact
     7321 ggaaaccatt gtccaaagtt tggaaaatgg tgaaattgct ctggaagatg cgattactgc
     7381 ctttcaaaag ggcatggtct tgtcaaaaga gctccaagct acgctggaca aggctgaaaa
     7441 gaccttggtc aaggtcatgc aagaagacgg aacagaaagt gattttgaat gaaaaagcaa
     7501 gaaaaattag ctcttgtcga gtcggctttg gaagattttt atggagacca gcagtttgcc
     7561 tctagtttac gggagtctgt tctctattct attcatgctg gtggcaagcg tattcggcct
     7621 tttctcttgt tagaagttct ggaagccttg caggttgcca tcaaacctgc tcacgcgcag
     7681 gtagctactg ccttggagat gattcataca gggagcttga ttcacgatga ccttcctgct
     7741 atggatgatg acgattatcg aagagggcgg ttaaccaatc acaagaaatt cggtgaagct
     7801 atggccattt tggctggaga tgccttattc ttagacccat atgccttgat tgcgcaggca
     7861 gatttgccaa gtcagattaa ggtggacttg attgccaact tatcccttgc ttcaggtagt
     7921 ctgggtatgg tggcagggca agttttggat atggagggcg aacaccagca cttgtctctg
     7981 gaagaacttc agactattca tgccaataag actgggaagt tactagccta tcccttccaa
     8041 gcggcagcta ttatagctga attgtcacct gaaatgcagg tgaagctgaa aactgtgggt
     8101 gaattgattg gacttgcttt tcaagtcaga gatgatgtac tggatgtgac agctagtttt
     8161 gaggaaatcg gtaagacacc tcaaaaggat ctgcaggcag aaaaatcaac ctatcctgcc
     8221 ttgttgggct tggaagagtc cattgccttt tgtaaccaaa ccctggatca agctaatgaa
     8281 aaattggaag aaattgccca gcaggttccc tttgaaacag aatcgattgt aagtgtagta
     8341 gaaagtttga gaatcaatgg ctaaggaaag agtggatgta ctagcttata aacaggggtt
     8401 gtttgaaacg agagagcagg ccaagcgagg tgtgatggct ggcctagtcg tagcagtcct
     8461 taatggagaa cggtttgaca agccaggaga gaaaattcca gatgataccg aattaaaact
     8521 caagggggag aaactcaagt atgtcagccg tggtggtttg aaactggaaa aggccttgca
     8581 ggtctttgat ttgtcggtgg atggcgcgac tacgattgat atcggggcct ctactggagg
     8641 ttttaccgat gtcatgctac agaatagtgc caagttggtc tttgcagtcg atgttggtac
     8701 caatcagttg gcttggaaat tacgccaaga cccacgagtt gtcagcatgg agcagttcaa
     8761 tttccgctat gctgaaaaga ctgatttcga gcaggagccg agctttgcca gtattgatgt
     8821 gagtttcatt tcccttagtc tgattttgcc agccttgcac cgtgtcttgg ctgatcaagg
     8881 tcaggtggta gcacttgtca aacctcagtt tgaggcagga cgtgagcaga ttgggaaaaa
     8941 tggaattatt cgagatgcta agattcatca gaatgtcctt gaatctgtaa cagctatggc
     9001 agtagaggca ggtttttcag tccttggctt ggacttttct cccatccaag gtggacatgg
     9061 aaatattgaa tttttagcgt atttgaaaaa agaaaagtca gcaagcaatc agattcttgc
     9121 tgagattaaa gaagcagtag agagggcgca tagtcaattt aaaaatgaat aaaaaagaaa
     9181 gacttgaaaa aattagaaga ttggtgacag attatcaaat cggcacgcaa gaagaaattg
     9241 tagaacattt gaaagaagca ggtatcactg ccactcaggc gacggtatcc cgagatatca
     9301 aagagttagg tattgtcaaa attcctttga gagacaacac ctatgtctac gaattaccaa
     9361 aatcaatcgt aaaaagtctg caactggctg aagacaatat cgaatcggct gaattgatgg
     9421 ataagatgat caatctccaa gttattccag gaaatacggc ttttgtaaaa gctcagttaa
     9481 tcgatacttt tgcagacaag atttttagtt gtttgactga tgatagctcg attttagtca
     9541 ttgccagaag tggaagtcta gcagaggaaa tctttgaaca agtaaaaaat tggtaggtct
     9601 atatgttact tgaaatttcg ataaaaaact ttgccattat tgaggctatt tccctcaatt
     9661 ttgaaaaggg gatgactgtc ctgactggtg aaacgggtgc agggaagtcg attatcattg
     9721 atgccatgaa tatgatgttg ggagctcgtg cgacgacaga tgttattcgt catggtgcac
     9781 caaaggcaga gattgagggg cttttctcag ttgagaatag tcgcctttta caggaaattt
     9841 ttgatgagca aggtttagaa ttaggtgatg aaattatcat ccgtcgggaa atcttgcaaa
     9901 atggtcgtag tatcagccgt gtaaatggtc agatggttaa tctgtctgtt ttgcgagcta
     9961 ttgggcaaca tcttgtagat attcatggtc agcatgacca tgaggagtta atgcgtcccc
    10021 aactgcatat ccagatgttg gatgaatttg gtgatgccgc tttttgggac ttgaaagaaa
    10081 cctatcaaac gagttttgat gcctatcgga aaatgcgcaa gcaggttctg gaagtcaaga
    10141 aaaaccaaca ggaacacaag gcacgtatcg aaatgttgga atttcaaatg gcagagattg
    10201 aggcagcaaa cttgcaggct ggagaagact tggctctcaa tcaagagcga gataaactcc
    10261 tcaaccacaa aaatattgcg gatacactga ccaatgccta cagtatgttg gacaatgaag
    10321 atttttcaag tctggccaat gttcgttcag ctatgaatga catggaaagt gtcgaagagt
    10381 atgatcctga ataccgtgaa atttcaagct ctctgtctga gacctactat gttttagaag
    10441 acattagcaa acgtttggaa gctatcattg aggaccttga ttttgatggc aatcgcctga
    10501 tgcaggttga gaatcgtttg gacctccttc atactattac tcgtaagtat ggtgggactg
    10561 ttgatgatgt tttgctttat tttgctaaga ttacggaaga atacaatctc ttgacaggca
    10621 ataatctttc gtctgaggac atggaagcag agcttaagaa gttggaagtc aatcttgtca
    10681 atttggcagg tcaacttgct tctgctcgtc ataatttggc tcagcaactc gaagctgaga
    10741 ttaaacaaga actgcaagat ctttatatgg aaaaagccca gtttcaggtt cgttttagta
    10801 agggaaaatt cagtcgtgag ggaaatgaaa tggttgagtt ttatatttca accaaccctg
    10861 gagaagactt taaacccttg gttaaggttg cttctggagg ggaattatct cgtctcatgt
    10921 tagccattaa gtctgccttt tcacgtaaag aaggcaagac tagcattgtc tttgatgagg
    10981 tggatacggg agtttcaggt cgtgttgctc aagctattgc tcagaaaatt cataaaattg
    11041 gtcagtatgg tcaggttttg gctatctccc atttgccaca agtaattgcg attgcagatt
    11101 atcaattttt tattgagaag attagtaatg accattcaac ggtttcgact gttcgtctct
    11161 tgacagtcga agagcgagtg gaggaagttg ccaagatgtt ggcaggtgat gatatgacag
    11221 aagcagccct gacgcaagcc agagaattgt tgagaaacag ggagaaataa gatgacagat
    11281 tattatgtaa ttggagatgt tcacggaaaa gctgggatgc tggaagacct tctcaaaacc
    11341 tgggatggtc agacccagtt gctctttcta ggtgatttga ttgacagagg tgaggatagt
    11401 caccgtgttc ttgaaatggt caaggacttg gtggacaatc aaggggctat ctgtttgtct
    11461 ggaaaccacg agtatatgtt tttgacttgg ctagatgacc cagaagaaag ttatgaccat
    11521 tatcgtcgca atggtggaga tacaaccatt aactctatcc taggtcgtcc cttggatgca
    11581 ccagttgatg gagtagaaga tgccaagcgg gttgccgctg aagcggcaga cttggtcgaa
    11641 ttcattcgtc aaatgccatt tgtagtagag acagacaagt atatctttgt tcacgcaggt
    11701 attgatttga ccttggacga ctggcatgaa acaacagatt ataaaaaagt atggcttaga
    11761 aaaccattcc acggagctga aaatcatact ggaaaaacca ttgtcttcgg tcatacaccg
    11821 gtctatggtt tgttacagca agaacgcggt acatctgagc tttggactac agaagatggc
    11881 aagattggaa tggatggagg agctgtttat ggtggtgtcc ttcacgggat tgtctttaca
    11941 gaccaaggaa tgacagaaca ccactttatc gaaaatgacg gctttgtcgc tgaagattag
    12001 tactcctagc agggtatggt cttgtcaaaa tatcaaaaac aatttataat aaatagatac
    12061 cctgaaagga agagaatcat gaacttagaa gaattgaaaa aacgacagga gaagatccgt
    12121 aacttctcta ttatcgccca tattgaccac ggaaaatcaa ctctagcaga ccgcattttg
    12181 gaaaaaacag agacggtttc aagtcgtgaa atgcaggccc agcttttgga tagcatggat
    12241 ctagagcggg aacgtggaat tactattaag ttgaatgcca tcgagttgaa ttacactgca
    12301 aaagatggag aaacttatat tttccacttg attgacacac cagggcacgt tgactttacc
    12361 tatgaagttt cacgttcgct agctgcctgt gagggtgcta ttttggtggt cgatgcggct
    12421 caaggaattg aggctcaaac tcttgccaac gtttatctgg ctttggataa tgatttggaa
    12481 atcatgccta tcattaataa aattgacctg ccggctgcag atccggagcg cgtgcgtaca
    12541 gagattgaag atgtgattgg tttggatgcc agtgaagcag ttttggcttc tgccaaggct
    12601 gggattggga ttgaagaaat cctcgagcaa attgtagaaa aagtaccagc accaacgggt
    12661 gatgtgacgg cgccacttaa ggccttgatt ttcgactctg tttacgatgc ttaccgtggg
    12721 gttatcctcc aagtgcgtgt catggacgga gtggtcaaac ctggtgataa gattcagctc
    12781 atgagcaata gtaagacctt tgatgtggcc gaagtcggta tttttacacc aaaagcggtt
    12841 ggtcgtgatt tccttgcgac tggtgatgtt ggttacattg cggcgtctat caagacggtt
    12901 caggatactc gtgtgggtga taccgttacc ttggcaacca atcctgcggc agaaccatta
    12961 catggttata agcagatgaa tcctatggtc tttgcgggtc tctacccaat cgaatcaaac
    13021 aagtacaatg acctgcgtga agcgcttgaa aaattgcaac tgaatgatgc tagtcttcag
    13081 tttgaaccag aaacatctca ggcacttgga tttggttttc gttgtggatt tcttggactt
    13141 ctccatatgg atgttatcca ggaacgttta gagcgtgagt tcaatattga cctcatcatg
    13201 acagctccgt ctgttattta caaagttaat ttgaccgacg gtgagtctat ggatgtgtct
    13261 aacccatctg agtttccaga cccaactaag attgcgacca ttgaagagcc ttatgtcaag
    13321 gcgcaaatca tggtaccaca ggagttcgtc ggagcagtaa tggagctagc tcagcgtaag
    13381 cgtggggact ttgtgactat ggactatatt gatgataacc gtgtcaatgt tatctatcaa
    13441 attcctcttg ctgaaattgt ctttgacttc tttgataaac ttaagtcttc aacacgtggt
    13501 tatgcaagct ttgactacga attgtcagaa tatcgcccat ctaagctggt gaaaatggat
    13561 atccttctca atggagataa ggtggatgct ctcagcttta tcgttcacaa ggactttgcc
    13621 tacgaacgtg ggaaactcat cgttgataaa ctcaagaaaa tcatccctcg ccaacaattt
    13681 gaagttccaa tccaagcggc tattggacac aagattgtcg ctcgtactga tatcaaggcc
    13741 cttcgtaaga acgtacttgc taaatgttat ggtggtgacg tttctcgtaa gcgtaaactc
    13801 cttgaaaaac aaaaagctgg taagaaacgc atgaaatcca tcggatcagt tgaagttccg
    13861 caagaagcct tcctcagcgt cttgagtatg gatgaagaat aagttatcag aaatgccttt
    13921 ccttgttcac aggaaattta tataagaatc aatagtaaag caggcttaga tggtctgctt
    13981 ttttagtttt tatactcttc gaaaatctct tcaaaccacg tcatcgtcgc cttaccgtat
    14041 gtatggttac tgacttcgtc agtttcatct acaacctcaa aaccatgttt tgagctgact
    14101 tcgtcagtct tatctacaac ctcaaaactg tgttttgagt aacctgcggc tagcttccta
    14161 gtttgctctt tgattttcat tgagtattag aacagaaaaa tgcttggagt atttgtttgt
    14221 gtgtttattt ttatataaca aactataaac aaaacaaaaa tataaaaaag agacaaaaaa
    14281 gaacagaaag taattaacaa cgatttcata tagtgttata cttatggcat aaagttaatg
    14341 gaaagaaggg aaaaccttat ggtattagat tatttctttg acaaaaacct tgtgctttgc
    14401 ttagaagcgg ataatcaaga acaactcttt gatcaggtag caagcttgtt ggaagaacga
    14461 gaaattgtca ctcctactta tcgtgaagcc ttgatcacgc gtgaaaagtc atttccaact
    14521 ggtttagata tggaatttct aggaaaggac ttgccaaatg tagcgattcc tcacacagat
    14581 attgttcata atctagctga gaaagtggtg gttgttcgat tagaaaaacc agtaactttt
    14641 cacaatatga tagctcccga taaggaagta gaagtatccc tactcttctt tatcattaat
    14701 aattcaagtt caagtcaaac gaacattctt gctcagttga tgaacttctt cacaggaaat
    14761 ggacatcttg aagacctatc aaaaatttcc gaaccagaaa aactttatgc ttatatagat
    14821 gaagcaatcg cttaatcttg tctattaaaa aataaaatcg gaggaagtct atatgattaa
    14881 aattcttgct gcctgcggtg caggtgttaa ctcaagtcac caaattaaaa gtactctaga
    14941 agaagaactt tcaaaccgtg gttacgatgt tcactgtgat gcagtcatgg tgaaagatgt
    15001 aaacgaagac cttatgaaag gttacgatat ctttacacca atcgctgcaa cagatcttgg
    15061 ttttgaacca ggtatcccag ttatcgaagc tgggccaatc ttattttgta tcccagcaat
    15121 gagcgctcca gtatttgaca atattagact ccctgcgaaa caaaatatgg tatagtagtt
    15181 ctatgaatga tgaagcaagt aaacaactaa ccgatgcacg atttaagcgt cttgttggtg
    15241 ttcagcgtac cacttttgaa gagatgttag ctgtatta
//
LOCUS       DAVHLA010000047        14400 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVHLA010000047 DAVHLA010000000
VERSION     DAVHLA010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14400
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.047"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(91..1140)
                     /locus_tag="VVO77_001742"
     CDS             complement(91..1140)
                     /locus_tag="VVO77_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5693721.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(1137..1868)
                     /locus_tag="VVO77_001743"
     CDS             complement(1137..1868)
                     /locus_tag="VVO77_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5693722.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            1936..2346
                     /locus_tag="VVO77_001744"
     CDS             1936..2346
                     /locus_tag="VVO77_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEU5693723.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMNATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            2356..2643
                     /locus_tag="VVO77_001745"
     CDS             2356..2643
                     /locus_tag="VVO77_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693724.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIIDQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            2804..2980
                     /locus_tag="VVO77_001746"
     CDS             2804..2980
                     /locus_tag="VVO77_001746"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693725.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSSKHCF
                     EVVDTTHIYTASRR"
     gene            complement(3009..4145)
                     /gene="dnaJ"
                     /locus_tag="VVO77_001747"
     CDS             complement(3009..4145)
                     /gene="dnaJ"
                     /locus_tag="VVO77_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEU5693726.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(4350..4703)
                     /locus_tag="VVO77_001748"
     CDS             complement(4350..4703)
                     /locus_tag="VVO77_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000115730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693727.1"
                     /translation="MSVNKNNLSDIADYHEKIKFFEELFNLDYNPTEMLVTVERNGNV
                     IYKEFTEVAVGKSKYDYTSVFKDVMIYFSDHICQELHLYKTQDPHYNKFEFDLAKRSL
                     KITTRDNTTIFISNE"
     gene            complement(4716..6539)
                     /gene="dnaK"
                     /locus_tag="VVO77_001749"
     CDS             complement(4716..6539)
                     /gene="dnaK"
                     /locus_tag="VVO77_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEU5693728.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(7019..7543)
                     /gene="grpE"
                     /locus_tag="VVO77_001750"
     CDS             complement(7019..7543)
                     /gene="grpE"
                     /locus_tag="VVO77_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEU5693729.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(7570..8604)
                     /gene="hrcA"
                     /locus_tag="VVO77_001751"
     CDS             complement(7570..8604)
                     /gene="hrcA"
                     /locus_tag="VVO77_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEU5693730.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRIADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQINVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(8768..9277)
                     /locus_tag="VVO77_001752"
     CDS             complement(8768..9277)
                     /locus_tag="VVO77_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HEU5693731.1"
                     /translation="MNSRVEFRIFTIVDLDKEEEYLHEMHLKGWRYRTSRFGLFYFDQ
                     CQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTTTFLGGLVVCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            9884..12217
                     /locus_tag="VVO77_001753"
     CDS             9884..12217
                     /locus_tag="VVO77_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU5693732.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFRPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAMVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGDPVKVLE
                     TGAKTVSGSTPGFVDKEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            12230..13693
                     /locus_tag="VVO77_001754"
     CDS             12230..13693
                     /locus_tag="VVO77_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEU5693733.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTNDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            13693..>14400
                     /locus_tag="VVO77_001755"
     CDS             13693..>14400
                     /locus_tag="VVO77_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU5693734.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRIKSIYWNFGQ
                     NKPEKSFRYIDTSSIDRKKNIINYKNLQYLSPEQAPSRARKLVSQNSVLFSTVRPYLK
                     NIAVVRELKEYLIASTAFIVLDTLLNETYLKYYLLSDNFINRVNNKSTGTSYPAINDY
                     NFNLLLIALPPLSEQQRI"
BASE COUNT         4492 a         2880 c         2792 g         4236 t
ORIGIN      
        1 tctctacgga ccaaccatta tcctgtagta acaaaaaaga agctgagaca gactgaactc
       61 aacttctttt ttagtgtcgt atcagcaatg ttagtcctgc atctgacgtt ttacctgata
      121 aggcaaatac aagactagta aaaccaaacc agctcctagt aaggctagaa gggccagttt
      181 ttcttggaag gtaatcaacc caacaactaa ttccacaagt aaaacaaaac tggtcaatcc
      241 tcgaactacc tcctgtaagc ctttttcctt ttgccccttg tccagcggaa agagttgggt
      301 caaatactgg tagtcaaagg catgatagag ggccagcaac tggaagagca agaggtagtt
      361 aaagagaact accactgctg tcgcaatcca agcttgctcg ataaaaacct gcgccagtac
      421 ggaaagtaat agaagacgaa gactgagagc aaagaggtcg ccatttcgca gataagaacg
      481 cagatagaga ttttgccaaa tcttcccagg caccttctga acagccttta agataaagtc
      541 cagataggca cgacgcttaa cgctgtttga aattcccttg acctgcgtaa agagggcaaa
      601 gaaacgaagc aagacttgct tacgcttgct ttcttgagaa ataacatagt cccagtccag
      661 tccagtttca gtgaaaaatt tgctggcctt ttgacgaaag tggaaatatt ttcctacccc
      721 caataaaagc acatagagca gaaaaactgg caagccataa cccattgcta aaaataaagg
      781 cgcaaataac agcaagaaaa gggtctgtac aaagagccaa aagactaggg aaatgccagt
      841 ttgacgcttg agatggagct tgatttcctc ttctccaact aagagaaaga gcttgtctgg
      901 agcctccata taggtggcaa ttcctcccca aagtaaaagt aaaacagacg taattcctac
      961 aaacaaaagg ataggccaat gattttcagg aaaatgttgt aagagttgac tgtactggta
     1021 ggctagaaag cccaacagga caagcaggaa caagacaaag tggtcattga gcacatagcg
     1081 cagataacca agacactcct tacgaaaggc ctgctttctc tttaaaaaca agtctttcat
     1141 aggtcctcct cttttgtcag agccaagtaa atatcattca aactagcctc aggcatatca
     1201 aaggcttcgc gtagttgcag gagattgcct ttggcacgca cctctccctt gtgaagaatg
     1261 acaaaggcat cacacatctt ctccgccgaa tccagcacgt gggtactcat gagaatagac
     1321 ttgccctttt gcttctccac ttccaaaagc tgaatcaaat cagaaatagc cagcggatca
     1381 agaccaagga aaggctcatc cacgatgaaa agacttggat ccaccacaaa agcacagata
     1441 atcatgacct tctgcttcat cccttttgaa aaatgaacag ggaaccagtc taatttctgt
     1501 tccaaacgga acatttttaa caagggctct actcgttcga aagccacttt ttgctcaata
     1561 ccgtaagcca tagcaaccgt ttcgatatgc tctctgaggg tcaattcctc atacagacta
     1621 ggcgtctcag gaatgtagcc aatctgcttg cggtagctag tcgcatctcc ttgcagagtc
     1681 aggccattga tattgatgga gccactataa ggtgccaaca gaccgataat ctcattgatc
     1741 gtcgttgatt tcccagcacc attgagacca atcaaaccga ccaactgccc actttcaaca
     1801 gtaaaggaca catctttcaa aacaggaaca tgaacatagc cacctgtcag gtttttaatt
     1861 tctaacatat tttctccaaa tctggtataa tgtagctata ttatatcaaa attcagtaca
     1921 gtagaggtag attttatgtc agattgcatt ttttgtaaaa tcatcgcagg ggaaattcct
     1981 gcttcaaaag tatatgaaga tgagcaggtc cttgcctttc ttgatatctc tcaagtaaca
     2041 ctaggacaca ccttggtcgt gccaaaagaa cactatcgca atcttttgga gatgaatgct
     2101 acgagcgcca gccaactctt tgcccaagta ccaaaagtag ctcaaaaagt catgaaagtc
     2161 actaaggctg ctggtatgaa tatcatttcc aactgtgaag aagtcgctgg tcaaacagtt
     2221 tttcatactc acgttcacct tgtgcctcgc tacagtgctg acgatgacct caagattgat
     2281 tttatcgccc acgaaccaga ctttgacaaa cttgctcaag tcgctgaaac catcaaaaac
     2341 gcttaaggag ttgctatgaa attatccaac ctactgctat ttgcaggagc tgcagccgga
     2401 agttatctgg ttacaaaaaa tcgccaaacc atcacagatg aagtcttaaa taccactgac
     2461 cgcgttcaag ctatcaaaga cgatgtggat attatccaaa atagcctgca aatcatcgac
     2521 cagcaaaaag aacttatcaa ggaataccaa gaagacttga cttacaagtt taaggtcttg
     2581 gaaaaggata tccagactag actagctgtg ataaaagaaa tgcagggaac tgaagataag
     2641 taaaaagagc ccccggctct tttttaaaac gtaaacaagt tatagtgaat tgaatttaga
     2701 atagcacatc atagtttcta aagcattgtt agagattact ttaaaatcct cttatcaatt
     2761 tgttcatatt ctatttcaat ctactatata tatcccatca actatgcatc ataatttagg
     2821 taactcatac tcaataaaaa tcaaaaagca aactagaaag ctaggcacag actgctcaaa
     2881 acaccgtttt aaggttgtgg atagaactga cgaagtcagc tcaaaacact gttttgaggt
     2941 tgtagatacg actcacatat atacggcaag ccgacgctga cgtggtttga agagattttc
     3001 gaagagtatt attctccatc aaaggcatct ttaatatggt caaagaagcc ttttttcttt
     3061 ggatttactt tcaagtcacc agcagccgcg aattctttca aggctacttt ttggcggtcg
     3121 ttcaagcctg tcggtgttac gacattaaca gtaacgtatt ggtcaccaac tgcaccgcca
     3181 cgaaggctcg gtgccccctt actacgtagg cggaatttct taccagtctg agttccctct
     3241 ggaataacca attcaacatc accgtgaaca gttggaatat ctactgtatc accaagagcc
     3301 gcttggacaa agttgaggtt gagattgtag aagatagtcg ttccttcacg ttcaaacttg
     3361 tcgctagctt ctacagaaac tactacatac aagtcaccat aaggtccacc gttaaagcct
     3421 gcttcacctt gaccagcgag gcgaatttgt tgacctgttt ccacaccagc agggattttc
     3481 acatgtacgc tatgagcttg tttctcatga cctgttccat gacaggttgt acatggatat
     3541 ttgatttctt ttcctcgacc gtgacagaca tcacaggtta cttggcgacg catcatacca
     3601 agaggagtct gcgtatcgac gttaatgaca ccagcgccat gacagcgtcc acaagtgact
     3661 ggacttgtcc ctggcttagc accagagcca ttacatgtac gacagccagc ttcacgatga
     3721 tacttaactt ccttctcagt tccgaagata gcttcttcaa aggtcaaatt gacacgatac
     3781 tggagatcat ctccttggcg aggagcgttt ggattgcgcg aagaaccgcc tccgccgaag
     3841 aaacttgaga aaatatcctc aaaaccaccg aagccacctg ccccattgaa accgccgaaa
     3901 ccaccagctc caccaaaacc accattggcg cctgcagcac catactggtc ataggcagca
     3961 cgtttttggt cgtcactcaa agtctcatag gcttcttgaa cttccttgta cttgtcctca
     4021 gcaccaggct ccttgttgat atctgggtga tattttttgg aaagcttacg ataagccttt
     4081 ttgatctcgt ctgccgaagc gttttttgac acccccagac gatcataaaa ttcagtattg
     4141 ttcatacaag ataccaagac cgtaaaattc gactgaaaaa taggaaatct gacgctggag
     4201 cgacgctcct agacagattt ctcttttttc cgagaattta ggtcgggttc aattcctttc
     4261 ttttatattg atgagataat actccagcca ctcggcccta tcccttttta ccgaaaaaca
     4321 gaggctgggt tgcaacctct gtggttagat tattcatttg aaataaaaat ggttgtatta
     4381 tctctagtag taatcttcaa agacctttta gctaaatcaa actcaaattt attatagtgt
     4441 gggtcttgtg ttttatatag gtgtaactcc tgacatatat gatccgaaaa gtaaatcata
     4501 acatctttaa acacagaagt gtagtcatat ttactcttac caacagctac ttctgtaaat
     4561 tctttataaa tgacatttcc atttctttcc acagtcacca gcatttctgt tggattataa
     4621 tccaaattaa ataattcttc aaaaaacttt atcttttcat gataatctgc aatgtcagaa
     4681 agattatttt tattaacact cataacacta gccccttact tttccgtaaa ctctccgtct
     4741 acgacgtcat cgcctgcgtt tcctgttgct tgtgcgcctt ctgctccttc ttgagcttgt
     4801 tgcgctgctg cggcttgttc gtagagttta acagcaagtc cttgagcttt ttcgttcaat
     4861 gcttcaagtt ttgctttcat gtcgtccaag ttgttgtctt cttgagcttt cttaaggtca
     4921 tcaagggcag cttgggcagc gtcacgttct gcgtcgaagc ctttaccttc agtttccttg
     4981 attgtctttt cagtcgcaaa gattgcttgg tctacttcat tacgaaggtc tacttcttct
     5041 ttacgtttct tatcggcttc agcgtttgct tctgcatctt tcatcatgcg gtcgatttct
     5101 tcgtcagtca aacctgagtt cgattggatg acaatagttt gttctttttg agttccaagg
     5161 tctttggcct taacagacac gataccgttc ttgtcgatat caaatgttac ttcgatttga
     5221 ggaattccac gaggtgcagc tgggatatca gtcaattgga agcgtccaag agtcttgtta
     5281 tctgctgcca ttgggcgttc accttgaaga acgtggatat caacggctgg ttggttgtct
     5341 gctgctgttg agaagacttg tgatttagat gttgggattg tagtgttgcg atcgataagt
     5401 tttgtaaata ctccacccat tgtttcgata ccaagtgaca atggcgttac atcaagaagg
     5461 acaacatcct tgacatcacc agtaatcaca ccaccttgga tagccgcacc catagcaact
     5521 acttcatcag ggtttactga tttgtttggt tctttaccag tttcagcttt aacagcttca
     5581 acaacggcag ggatacgagt tgaaccacca acaaggataa cttcgtcgat ttctgacaag
     5641 ctcaaacctg catctgaaag ggcttgacga actggaactt ttgtacgttc aacaaggtca
     5701 cgagtcaaat catcaaattt cgcacgagtt aaagtcattt ccaagtgaag aggtccagcc
     5761 tcacctgcag tgataaatgg caagctgatt tgtgttgaag ttacaccaga aaggtctttc
     5821 ttcgcttttt cagccgcatc tttcaaacgt tgcattgcca tcttgtcagt agacaagtcg
     5881 ataccgtttt ctttcttgaa ttctgctacc aagtggtcaa tgattttttg gtcaaagtcg
     5941 tcaccaccaa gtttgttgtc ccctgcagtt gacaatacgt cgaagacacc gtcacccaat
     6001 tcaaggatag agacgtcgaa tgtaccacca ccaaggtcaa ataccaagat tttttcttct
     6061 ttgtcagtct tgtccaaacc ataagcaaga gctgctgcag ttggttcgtt aacaatacgt
     6121 tctacttcaa gaccagcaat tttaccagcg tcttttgttg cttgacgttg agcgtcgttg
     6181 aagtaagccg gaactgtgat aacagctttg gttactttct caccaaggta gtcttcagcg
     6241 tagcctttca agtattgaag gatcatagct gagatttctt gtggagtgta ttcttttcca
     6301 tttgcagaaa ctttttcaga agttcccatc ttagatttga tagagataac tgtatctggg
     6361 tttgtgactg cttgacgttt tgcagcatca ccaacgatga tttctccgtt tttgaatgag
     6421 actacagatg gagttgtgcg gtttccttct gggtttgcga tgattttgct ttcagttcct
     6481 tcaagaactg caactgctga gtttgttgta cctaagtcaa taccgataat tttagacatg
     6541 tgtttttctc cttgttagtt aattttctat ttttcttttt gatactcttc ttaagtggcg
     6601 acgccgtcag agcttgactt cgtcaatctc tttgactaaa ctttgagcct aaggtctcaa
     6661 aatttgcgca aatagcgcca cggcgaagag tatcgtgttt ggttcgcttc gctcactatt
     6721 acaaagccaa acatatttta tctttcttca tagtttattg tcgtttcgga caagttttct
     6781 attatgtaaa ttgcgacacg aagagtcgaa atcgatttta tttcgacgac gagttagtaa
     6841 ggaagctagg caaacgccat agcgattgcc gttttctgac gagttgcttt agctaccgtc
     6901 agaattgccg aatcgaacac gccctaagct ctgagtaaaa aagatagatt ttcttgtgtt
     6961 catcgaacac ttcgtcaatc tcctattttt actgcgagct ttttacgggc tttgtatctt
     7021 agttatacac cactaccatt gctgggcgta ggatgcggtc atggagtttg tagccttttt
     7081 gaaagacttg agcgatggta tctactgggt gttcatcgtc tgctgggaga gtttggatgg
     7141 ccatatggta gttatggtca aattcgccat ctgctgcgat ttcttcaatt ccttcttctt
     7201 tcaaagcgtg aatcaagctt tcttgcacca tccccaagcc cttcttcaca tcatctgtca
     7261 aaccttcaac tgcaagtgca cgctcaaggt tgtcaagaga tggtaagatt gcttttgcca
     7321 agtcctggct acgataacgt tgcaagtttt gacgttcttc attggcacgg cgttggatat
     7381 tttgcatttc tgcatgagcg cgaagatatt tgttttcgaa ctcatctgca cgttcatttg
     7441 ccaagtccaa ctcagacttt tcaggagttg tttcttcagc tgtttccaca acttcctctt
     7501 cttgaacttc ttctacttct tcatttttta tatcttgggc catgttcgcc tcctttaatg
     7561 atttcaatct taatgtactt cgtaatgatt actgctgagg tagcggtaaa aatctgtcaa
     7621 cttcatggtc aaaacacggt tgaccacatt gatttgattg attagctgtt ggtaatccag
     7681 attaactgga ccgataatgg ctagaattcc aactccccga taaggaatga ggaacttact
     7741 actaatcacc gctaggtcag ctaaacagga ctcttgaccg tctgcaatac gaacattttg
     7801 catctgatcc tcacgcaacc cctcacgaat ctccaaggcc accttttgcg gttggtcaaa
     7861 gaactgatag gctgctagat tggcaaaatt caagagattg accttgcccg ccatcacaat
     7921 gttttcgttg aacatttcct taaagatgtg ttcaaagaga tcgatgacat tatccgttgt
     7981 tgtaaagtaa cgctggataa tctgcggaat ctccgtccga atcttgtagt gaatatctaa
     8041 aacggtgtga ccgaggaaac gttcctgaat gatgctcttc agtttcagca aatcctcctg
     8101 caagaagttc cttggaatca gaaactgact agtaaccgtt cgcgactcgt ctagggtaaa
     8161 taccgccaag gctgtatgtt gccccaaaac aacgatatca aaggctgtca aacgttgcct
     8221 gctcggctca acatccagtg ccactaccgt acagccactc aggtctgtta gcaagttagc
     8281 agcctcttgc agaatatcct ccaatttgaa gaattcctga tcaaaggctt tgacaatctc
     8341 atatacctca ttttcagcca gccggtgaaa atccagtgag tgtttcacat agtactgaaa
     8401 accagcaaca cttggcatcc gaccgcttga agtatgagcc ttctcaagca acccttgttt
     8461 ttctagttcc gccatgtcat tacgaatggt tgcactgcta gagttaatag actcttgcaa
     8521 ggcttttgat ccgacaggtt cgtgcgtttt ggtaaagatg tcaataatca gatttaaaat
     8581 atcctgctga cgctctgtaa ccatctcatc actcctctct gtctgatcaa ttagcactca
     8641 atgcatccaa gtgctaactt atgattctat tatacaccct tagaagagaa tgtcaagaca
     8701 aaaactcaaa aaattagcac tcttttatca agagtgctaa aaatcaatct gaagacctag
     8761 aaccttgcta ttcatctact cggtatttcc tttttagtct gaaataacca tgaattagat
     8821 aagaaatcag aaaagcatat aaaacaaaaa taagaaagaa agacatagaa agatcctctc
     8881 taaacaaact cgtacaaaca acaagaccac ctaagaaagt agttgtacag gaacgaagtc
     8941 tagatcgcat aacttcccat ttgagcccct tactcatata gacttgatcc tctggaagta
     9001 aatcagaaga cgatttacga agaatcgaac aagaacctgc tcctatcaat tcccaacctc
     9061 tatctctaaa atcttgcagt tcatgcttat attttttaag aaatctagaa tcatagatac
     9121 ggtagatgac atcgtctggt tgacattggt caaaatagaa caaaccaaaa cgactcgttc
     9181 tatacctcca acctttcaaa tgcatctcat gtaaatattc ttcttccttg tccaaatcaa
     9241 caatagtgaa aatccgaaat tctactctgc tattcattgt cttaccccaa aattagaaaa
     9301 catgcctggc gttatttatt agataattct ttccgctttt gactcaatct ccaaaaaata
     9361 taagaaatct gaatcgcaaa aactatcaat aaaacccaat ctattatgaa agtcaaaaac
     9421 acttcccaac tgaaagaact acctccagtg acaaactttg agaaaaacgg tagtagagct
     9481 aaaaagagaa gcaaaatagg aagcatccgc attgttaaaa tccttttggc ataaaaaaat
     9541 ctttatttaa acgaaaatat tatggcaaaa tttacgccag tttttgaacg gctgatgtag
     9601 atattttata ctttcaaaat gtttaaatgt gattatttat ttttgaaaaa tagctcacca
     9661 gcccgactga aagtgcttat aaatgataat aagtcgcctg ccgaaaacag cgaaaaatag
     9721 cggtgttatg cggagataat ctgacgcgat gcgaaagtat attgcatact tattttcaac
     9781 aatttagcag agtattttta taagtgtgat ataatagaag tataatttgt tctgatagtt
     9841 tattttatgg agaagtagat ttttagaatg cggagggttc aatatggttg agtttataaa
     9901 gtctaagaaa gaaatgagtg aggaggatat taaagcaaat ttcatcactc ctgctattgt
     9961 atccaaagga tggaaaaatg gtgagcatat cgcttacgaa gaatacttca ctgatggtcg
    10021 aattgaggtt agaggagata aggctcgtcg taaagaagga aaaaaatcag actattcact
    10081 gtattaccaa tttggaactc gaattgcaat tgttgaggca aaggataata aacacagcgt
    10141 tcgagcagga ttacaacaag ctattgaata tggagagatt ttagatgttc catttgttta
    10201 ttcttcgaat ggtgatggct ttattgaaca cgaccgtatc acgagagaag aacgtgagct
    10261 ggagttagac gaattcccta ctcgtgaaga attattttct cgtatgacga aggaaaaagg
    10321 attgacgtac gaaattacag aagctatctc aactccatac tatacagacg ccttctcaat
    10381 gaaaacgcca cgctattatc agcaaatagc tatcaaccgt actattgaaa cagttgccag
    10441 aggacaaaaa cgagtaatgt ttgtgatggc aacaggaacg gggaaaacgt tcatggcttt
    10501 tcaaattatt catcgccttc gaaaagctgg tttggctaaa cgagttttat tcttagcgga
    10561 tagaaacatc ttagtagacc aaacgatggc tgaagacttt aggccattcg aaaaggtaat
    10621 gacgaaaatt acaccaaaac ttttgactgc tcctgaaaaa ttaaattctt ttgaaattta
    10681 tctagggctt tatcagcaac taactggtga agatggaact gaaacacatt atcaaaaatt
    10741 tgacaaagac ttctttgatt taatcgtaat tgatgaagcg caccgtggtt cagctaagga
    10801 aaacagtaac tggcgtaaga taattgatta tttcagttct gcgacacaga ttgggatgac
    10861 cgctactcct aaagaaacca agaatgcttc caatacggaa tactttggtg agccaatcta
    10921 tacttatagt ttaaaacagg gaatcgagga tggttttttg gctccatatc gtgttatgag
    10981 ggttaattta gatgtggatg tggatggtta tcgtccagaa actggaaaag ttgatgctaa
    11041 cggacaatta atagaagata ggtactacgg caggaaagat tttgataaaa ccattgtcat
    11101 tgatgataga acgcaaagag ttgccaagtt tgtttctgat tatatgaagc aaaacaatgc
    11161 acgatttgat aaaacaattg ttttttgtgt tgatattgac catgccgagc gaatgcgtgc
    11221 tgcacttgta aaagagaatc tagacttagt ccaagaagac tatcgttatg tcatgcaagt
    11281 aactggtgac aacgctgaag gaaaagctca actggataac tttatggatg tcaattctaa
    11341 ttttcccgct atggtaacaa cgtctaaatt attaacgaca ggagttaatg ctaaaacatg
    11401 tcgtttgatt gttttagact ctaatatcca atccatgact gaatttaaac aaattattgg
    11461 tcgtggcaca cgtctttatc ctcaaaaggg gaaagaattt tttacgatta ttgattttcg
    11521 aaatgttacc aatttgtttg ctgaccctga ttttgatggt gatcctgtga aggtgctgga
    11581 aacaggtgcg aaaacagtca gtggttctac gcccggtttc gtagataagg aaggtgaccc
    11641 agtagaaaaa tatatcgtta cagacaagca ggttaccatt cttaattcta ctgttcaagt
    11701 attggatgaa aacgggaaac tgattaccga aagcctgacc gactacactc ggaagaatat
    11761 cttaggtagc tacgccactt tgaacgattt tatcacagtt tggcatacgg cggataaaaa
    11821 gaagcttatc ttagacgaac tttataaaaa aggagtttat ctagatgcta ttcgagagtc
    11881 ggagggaata tcagaacaag aaatcgatga ttttgattta ctcctaaaac ttgcctatgg
    11941 tcaaaaagaa ttaaccaaaa cggaacgtat caataaactc aaacaaagcg gatatttata
    12001 taaatatagt gaggaagcgc gtgctgtttt ggaaatttta ctgaacaaat acatggataa
    12061 aggtattgga gaactcgaaa gcattgaaac attaaaactt ccagaatttc agatatatgg
    12121 tggaaccttc aaaatcatca atacttattt tggagataaa aaacgatatt tacaagcaat
    12181 taaagaattg gagcaagagc tatttacagt agcttaatga aaggaaagta tgtcaattac
    12241 atcatttgta aaaagaattc aagatatcac tcgaaacgat gctggtgtta atggtgatgc
    12301 tcaacgtatt gagcaaatgt cttggttatt attcttaaaa atttatgata gccgtgaaat
    12361 ggtttgggaa ttagaagaag acgagtatga gtcaattatc ccagaggaat taaaatggcg
    12421 aaattgggct catgctcaaa atggggaacg ggtattgaca ggcgatgaat tacttgattt
    12481 tgtcaataac aagttattca aagagttgaa agagcttgaa ataacttcaa atatgcctat
    12541 tcgaaaaacg attgttaaat cagcttttga agatgcgaac aactatatga aaaatggcgt
    12601 cttgttacgc caagtcatca atgttattga tgaagttgat ttcaatagcc ctgaagatcg
    12661 tcattcgttt aatgatattt acgaaaaaat tcttaaagat attcaaaatg ctgggaactc
    12721 aggagaattt tatacgccac gtgcagcgac tgattttatt gccgaagttc ttgacccaaa
    12781 acttggagaa tcaatggcag accttgcttg cggaacagga ggcttcttga cttcgactct
    12841 gaaccgttta agtagtcaac gtaaaactag tgaagatacc aaaaaatata atacagctgt
    12901 ttttggtatt gaaaagaaag catttcctca tcttttagca gttacaaatc tgtttcttca
    12961 cgaaattgat gaccctaaaa ttgttcatgg aaatactttg gagaaaaatg ttcgtgaata
    13021 tacgaatgat gaaaaatttg acattattat gatgaatcca ccttttggag ggtcagaatt
    13081 agaaacaata aaaaataact ttccagcaga attacggagt tctgaaacag ctgatttatt
    13141 tatggctgtc attatgtatc gtttgaaaga aaatggtcgt gttggagtta ttttacctga
    13201 tggttttcta tttggtgaag gtgtaaaaac tcgcttgaaa caaaaactgg tagatgagtt
    13261 caacttgcat acgattatta ggttgcctca tagtgtcttt gcaccgtata caggaatcca
    13321 tacgaacatt cttttctttg ataaaacaaa gaaaacagaa gaaacttggt tttatcgttt
    13381 agatatgcca gatggttata aaaatttctc gaaaactaag ccgatgaagt cagaacactt
    13441 caatcctgtt cgtgactggt gggaaaatcg tgaagagatt ctggaaggta agttctacaa
    13501 atctaaatca tttacaccta gtgaattggc tgagttgaat tataatttag accagtgtgg
    13561 ttttccaaaa gaggaagagg aaatcttaaa tccctttgag ttgattcaga attatcaagc
    13621 ggaaagagca actttaaatc ataagattga taatgtatta gctgatattt tgcagttgtt
    13681 ggaggacaaa taatgacacc agaacaactt aaagcaagta ttctccaaag agcgatggaa
    13741 gggaaattag tgccgcaaaa tcccaatgac gaacctgcaa gtgaattatt aaagagaatt
    13801 aaagctgaaa aagaaaaact tatcagtgaa ggaaaaatca aacgagataa aaaggaaact
    13861 gagatatttc gtggtgatga tgggaaacat tatgggaagt ttgctgatgg aagcactcaa
    13921 gaaattgatg ttccttatga tattcctgat acttgggagt gggtgaggat aaaatcaatt
    13981 tattggaatt ttgggcaaaa taagccagag aaatccttta ggtatataga tacgtctagt
    14041 attgatagaa aaaagaacat aatcaactac aaaaatctac aatatctttc acctgaacaa
    14101 gcgccttccc gtgctagaaa attagtttcg cagaatagtg tcttattttc aacagttaga
    14161 ccatatctaa aaaatattgc tgtagttaga gaacttaaag agtatttgat agctagtaca
    14221 gcatttattg ttttggatac tttacttaac gaaacatatt tgaaatatta tttattatca
    14281 gataatttta tcaatcgtgt taataataaa tctactggaa caagttatcc tgcaatcaat
    14341 gattataatt ttaatctatt attaattgct ctccccccac tatccgaaca acaacgaata
//
LOCUS       DAVHLA010000048        14282 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVHLA010000048 DAVHLA010000000
VERSION     DAVHLA010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14282
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.048"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(<1..1276)
                     /locus_tag="VVO77_001756"
     CDS             complement(<1..1276)
                     /locus_tag="VVO77_001756"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEU5693735.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIVMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLG"
     gene            complement(1354..2601)
                     /locus_tag="VVO77_001757"
     CDS             complement(1354..2601)
                     /locus_tag="VVO77_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEU5693736.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTFFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNAYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLDLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            complement(2792..3643)
                     /gene="rgg"
                     /locus_tag="VVO77_001758"
     CDS             complement(2792..3643)
                     /gene="rgg"
                     /locus_tag="VVO77_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HEU5693737.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELLV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIIIKSYMKSIDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            3767..4108
                     /locus_tag="VVO77_001759"
     CDS             3767..4108
                     /locus_tag="VVO77_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEU5693738.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIEDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            4166..4246
                     /locus_tag="VVO77_001760"
                     /pseudo
     CDS             4166..4246
                     /locus_tag="VVO77_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(4362..6065)
                     /gene="ilvD"
                     /locus_tag="VVO77_001761"
     CDS             complement(4362..6065)
                     /gene="ilvD"
                     /locus_tag="VVO77_001761"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEU5693739.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIIDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(6298..7230)
                     /locus_tag="VVO77_001762"
     CDS             complement(6298..7230)
                     /locus_tag="VVO77_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEU5693740.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSYSDIVVLEADLSSSMATNNLEK
                     NFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPEAVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(7227..8084)
                     /locus_tag="VVO77_001763"
     CDS             complement(7227..8084)
                     /locus_tag="VVO77_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU5693741.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            complement(8088..9434)
                     /locus_tag="VVO77_001764"
     CDS             complement(8088..9434)
                     /locus_tag="VVO77_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU5693742.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(9447..9731)
                     /locus_tag="VVO77_001765"
     CDS             complement(9447..9731)
                     /locus_tag="VVO77_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU5693743.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(9735..11765)
                     /locus_tag="VVO77_001766"
     CDS             complement(9735..11765)
                     /locus_tag="VVO77_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEU5693744.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLINQVVKDYYEKLQLVPIVNQLKVCLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKCYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            11956..12963
                     /locus_tag="VVO77_001767"
     CDS             11956..12963
                     /locus_tag="VVO77_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEU5693745.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGVFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            12966..13166
                     /locus_tag="VVO77_001768"
     CDS             12966..13166
                     /locus_tag="VVO77_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU5693746.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            13318..13500
                     /gene="rpmF"
                     /locus_tag="VVO77_001769"
     CDS             13318..13500
                     /gene="rpmF"
                     /locus_tag="VVO77_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEU5693747.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            13516..13665
                     /gene="rpmG"
                     /locus_tag="VVO77_001770"
     CDS             13516..13665
                     /gene="rpmG"
                     /locus_tag="VVO77_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU5693748.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(14145..>14282)
                     /locus_tag="VVO77_001771"
     CDS             complement(14145..>14282)
                     /locus_tag="VVO77_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693749.1"
                     /translation="ESGSMATGWFTVSGKWYYTYNSGDLLVNTTTPDGYRVNANGEWV
                     G"
BASE COUNT         4599 a         3018 c         2463 g         4202 t
ORIGIN      
        1 atcctagttt ttcaaagatt tctgagaagt tttggctgat tgtctcaagt gacacttgca
       61 cttcttctcg ggtttggttg ttcttgaccg tcacttgtcc gctttcgact tcgctctctc
      121 ctagggtgat gagggtctta gccgcaaaga catctgctga cttgaactga gctttgagct
      181 tacggttgag gtaatcacgc tctgctttga aaccttgttg gcgaagagct tggactagtt
      241 ctagggcttt gacatttgct ccatcaccca agactgcgat atagacatct agggcgtttt
      301 cgatagggag ggccacgcct tgtttttcaa ggatgagaag caggcgctct acaccaagcc
      361 caaaaccaaa tccagcagtt tcagggcctc caaagtaagc aaccaaacca tcgtagcgac
      421 cacccgcaca gactgtcaag tcattgccct caatctctgt gataaactcg aaaatggtgt
      481 ggttgtagta gtccagacca cgcaccatat tggtatcgat gatgtaatct actccaagat
      541 tttccaacat ctgacgcaca gcatcaaaat gagtttggct ttcttcatca agaaagtcca
      601 agatagacgg cgcattctct actgccacct tgtcttcttt ttccttagag tccaagacac
      661 gaagaggatt ttcctccaag cgacgttggc tatccttaga caaggtctcc ttgagcggtg
      721 tcaaatagtc aatcaaggct tggcggtagg ctgcacggct ctcaggattt ccaagagtgt
      781 tgaggtgcaa tttgacacct tgaataccga tttccttcaa aaaatgggct gccataacga
      841 ttgtttccac atcggtagct ggattgctag agccaaaaca ctcaacacca atctggtgga
      901 attggcgcaa gcgccctgcc tgtggacgct cataacggaa cataggtccc atgtagtaga
      961 acttgcttgg cttttgcact tctggggcga agagtttatt ttccacatag gaacggacaa
     1021 cgggcgcagt tccttctgga cggagggtaa tatggcggtc acccttgtca tagaaatcgt
     1081 acatttcctt ggttacgata tccgttgtat ctccgacaga gcggctgata acctcgtaat
     1141 gctcgaaaat aggcgtacgc acttctgcgt agttgtagcg cttgaaaatc tcacgggcaa
     1201 agccctcaac gtactgccac ttagcagact cagcaggtaa aatatcctgc gttccttttg
     1261 gtttttgtaa tttcataggg aatcctcttt aaacttaata gtcttatttt accataaata
     1321 gagggattaa aacagtgaga aaaaaattag gatttagata tcatttttga gattaagaat
     1381 tgtcaaaaaa atagctagca aggaaagacc aacaaatagc atccaagtca actgtatatt
     1441 ccatacggct actagtgaaa aacaagctgt tcccacaggt atggataagg taaacaatag
     1501 atctaaaaaa ttactagtac gagctagaac ctctggagct agatttttca tgagcatggc
     1561 actaatcttt ggttgaactt taccagacac atacagagta aagaagagaa atagcaaacc
     1621 aagcacgact tgattgaata aattagccaa accaactaga ctaagtccta cagtcgccca
     1681 catcatcaat ctaggcaagg actgcttccc aaaataagca ttgcccgtaa ggctactgat
     1741 gatgattgct actaaaacac agaattgatt gataaatagt gcctctgtat aagaaaaatt
     1801 caagagagaa tggctcaaaa agaagatatt ataaattcca cccaaagcgc cacccaagga
     1861 attaataagc aagacagcaa agagcataaa accaaagttt ttctgcccac ttttaagaaa
     1921 aacgagacgt aaatttcggt aaattgttag gaactggtct ttgatagaaa gcttctcatt
     1981 ttttaagttt tcaccatcag cagatgacat tgacaggctc aatttgcttt ttcctaaaaa
     2041 gaggatagtg gctgatacta ggaaaaagca ggcattgatt cccgcaacga gagaaaaatt
     2101 gttgaccgat agagctaaga gccagactcc gaaagcttga ccaccaatag ctgaaatata
     2161 ggtgatgaac tgtgaaaaag aataagcctc catcagatca tcttcagcta ctttttcctt
     2221 aataagaggc atacgcaggc cacctgcaaa atcactgatg atatcactaa tgacattgat
     2281 caaacacagg ctagaaaagg caaagagact agcttgctga acaactaggg ctgctagaaa
     2341 aaatagaacc gcctgaaaca aaccgctata gaccatccat ttgaccttgt ccctcgtgta
     2401 atctgcccga atccctgcaa aaactgtaaa gaaggtcgga agaatcatga caatattcgc
     2461 catagcaaca gcaaaagatg cttgtgacaa ggtcgatgca tagacgataa agaccaggtt
     2521 gaaaatcgaa gcaccaaaag cattgaagaa gcgtgataaa gtcaaaattc tataagctgg
     2581 atttctaaac aatagtttca tagataatct ccctccttgt tctaagttct acatcaagaa
     2641 tagctttagt atagcactta tgaatttgcg aaacgattct tttgaatata tgcaacaaac
     2701 aaaatgagca aaaaaacgat agaacttttg taatgacctg agagagggta acagttctat
     2761 cgcttcaaat tttttcttgg tttgcagata ctcaacattc ggtcgtattt ctatagtatt
     2821 cggcagattt attacagcca agcatctcaa aaatacggac agcatcctcc atctttttct
     2881 ggccttcctt gactctacct tgcttgctat caaggagacc ttctgcccac agataaacaa
     2941 ttcggaaata ggtctcattt tccttgtaga aatgctcttc gataacacgt ttaaaataat
     3001 aggcattggt aaattcttca cactcaatac tagctaaaaa gccattcaat agtatagtat
     3061 gaaaaaggtt tcgattgcca gacatttcca ttagaaaatc agatttacgt accatttctc
     3121 gtacatatct agtaaaaaga gaaacagata aaaatggaga actgactgaa aataaattga
     3181 gttcatagat tccccagatc tcggtagaaa acaaataatc atgaaggact tttccttcct
     3241 ctgctgttaa ctctaccctt tcatctatgc tcttcatata agacttgata ataatggcat
     3301 ttagaatatg tttctgtttg ttgtgagaat gggcatgctt ttgatactcc ctgcgatata
     3361 agtcctcaag aggtgctata ttctttggtt ccaagacatc tgtaatttct tttctcaact
     3421 cagaatctgt atcatactgg aaacctctcg ccagaaagag gatctcctcc acactggcag
     3481 atatattttc cagagcaaat agaaactttt ccaccaaaag ctcactctga cctgtttcaa
     3541 aacgggacaa catagacggc gaaaattgtc ctccggttgc ttgtctcagt gagatatttc
     3601 ttgactctcg taattgtcta aagacttttc caatctgctc catagacttc cccttgattc
     3661 cgtattttct tcattttatc atatttttca gaaaattcat caaaaacttg ccaaattgtc
     3721 agaattatga gaaaatagag gatatttatc acgtggaggg actgctatga gagacgatat
     3781 caaaatcaat gaccgtgctt tggccttgca agaccaaatt atcgaaaaac tagagaaagt
     3841 ttttgataca gatgtggaat tggatgttta caatctaggt ctgatttatg aaatcaatct
     3901 ggatgaaacg gggctctgca agattgtcat gaccttcacc gatactgcct gtgattgcgc
     3961 cgaaagcctg cctattgaaa tcgtggcagg tctgaaacaa atcgagggta tcgaagatat
     4021 caaggttgaa gttacctggt cgcctgcttg gaaaatcaca cgaatcagtc gctatggccg
     4081 tattgccctt ggactaccac ctcgttaagc aggccaatca cttttaaaga tgaaaaaagc
     4141 aagccgaaaa tggcttgctt tttgatactc aatgaaaatc aaagggcaaa ctagaaaact
     4201 agccgcaggt tgctcaaaac actgttttga agttatggat agaactgacg aagtcagctc
     4261 aaaatactgt tttgaggttg tggatagaac tgacgaagtc agtaaccata cctacggcaa
     4321 ggcgacgttg acgtgatttg aagagatttt cgagtatgag tttatttttt acctgacttg
     4381 tccatattcc agaagtctgt cacggctccg cgtgaagcag atgatacgat gtgggcatat
     4441 ttaccgagga caccacggct gtaaagtggt ggcaaggttg tttctgcctt gcgtttttca
     4501 agttcttctt cggatacggc catggaaatt tctttggtat cttggtcaac cgtaacgata
     4561 tcgccggtac ggagataggc aattggtcca ccatcctgag cttcaggagc gatatgtcca
     4621 acaaccagac cataagtacc accagagaaa cgtccgtccg tcaagagggc caccttatct
     4681 ccctgacctt taccaacaat cattgaagaa agtgacagca tctcaggcat accaggacca
     4741 cctttaggtc caacaaaacg aacaacgact acatcgccat caatgatttc atctgtcagg
     4801 acggcctgaa tcgcatcttc ttctgagtca aagaccttag ctggcccaac gtgacgacgc
     4861 actttaacac ctgatacctt ggcaactgca ccgtcaggag caaggttccc gttcaagatg
     4921 ataagcggac catccgcacg ttttggattt tcaagtggca tgataacttt ttggcctgga
     4981 gtcaagtctg caaagtcagc caagttttca gctacagtct taccagtaca tgtgatgcga
     5041 tctccgtgaa ggaaaccatt tgccaacaag tacttcataa ccgcagggac accaccgact
     5101 tcgtagaggt cttggaagac atactgacca gatggtttca agtcggccaa gtgaggcaca
     5161 cgttcttgaa tcgtattgaa gtcctcaagt gacaagtcaa catttgcggc atgggcaatg
     5221 gcgagcaagt gaagagtggc gtttgtagaa ccaccgagag ccatcgttac agtaatagca
     5281 tcttcaaagg cttcacgagt caagatatct gatggtttga gaccaagttc caacatctta
     5341 acaacagcac gtcctgctgc ttcgatatct tctttcttat cagctgattc agctgggtga
     5401 gaggatgacc ctggcaaact catccctaga acttcgatag cagttgccat ggtattagca
     5461 gtatacatac caccacaacc accagggcca gggcaggcat tacattcaag acgtttcacg
     5521 tcctcagctg tcatgtcacc gtggttccat tttccgatac cttcaaagac agaaaccaag
     5581 tcgatatctt taccatcaag atttcccggt gcaatagttc caccataggc gaaaatagct
     5641 gggatatcca tattagcaat agcaatcata gatccaggca tgttcttgtc acagccaccg
     5701 atagcgacga aggcatccac gttgtgacca ctcatagccg cctcgatgga gtccgcgatg
     5761 atgtcacgag atgttagaga gaaacgcata ccaggcgttc ccatagcgat cccgtccgct
     5821 acggtaatgg ttccaaactg tacaggccaa gcgcctgcag atttgacacc ttctttagcc
     5881 agtttcccga aatcatgcaa gtgaatgtta catggtgtat tttccgccca agtcgaaatc
     5941 actcccacaa tcgatgtttc aaagtcctta tctgtcatac cagtcgcacg aagcatagca
     6001 cggttaggtg atttaaccat gctgtcataa atgctactgc ggtgacgttt atctaattca
     6061 gtcatcttat ccctcccatt tcagttttta ctattatagc acaatttaaa ggcaatgaac
     6121 agaataaaat tcttgaattt tcagaaaatt ctatacgcat gtgaaatatt taaaattaaa
     6181 aacaacaaag cggattagtg cactttctga tgaccagaat atgcttttta atccgctttc
     6241 tttaaataac gtactgtaat ttttacagaa attctttcag ataagtgtat ttaacatcta
     6301 tcttgcatta taaatttcta gaaccttctc ttttatattc gattcactca aaccatactc
     6361 attaagaaga taatccattt tccctacttg accgaatctt tcttgaacac ccatccgatg
     6421 aatttttgtt attccatcat cagagaataa ttcacataaa gcactgccaa ttccacctat
     6481 ctgattgtgg ttttctacag taaatatagt ttttccactt aacattgttt ttatctgttc
     6541 tggtatcggt ttgattctaa ataaatctat cacacctact gaataaccta atttagacag
     6601 ttcatctgca actcgaatac ttggagcaac cattatgcca gaagcaacga ttacaagatc
     6661 ttcaccatgt cttaactcaa tgtagccctt agaaaaatct tctccacctt gatatacagc
     6721 ctctggagct tttctaattg ttcgaatata ttttagtcct tttaagtcta atgtctgatt
     6781 caatatttca cgaaattgga tatcatcagt tgcttcaaaa atgattgatt taggaattaa
     6841 acgtaacaat ccaatttctt caaatggcat atgtgtccca ccattcattt ctgcagttac
     6901 tcctgcatct gatccaatca cagtggcatc caattgtgcg tatccaagag aaataaataa
     6961 ttgatcaaat actcttcgtg aagcaaaagg accaaatgta tgaagataag gtctaaaccc
     7021 ctgaatagac aagcctgctg caaggccgac catttctgct tccataatcc caacattcac
     7081 ataacggtct ccaaagttct tttcaagatt attagtagcc atcgaacttg acaaatcggc
     7141 ttctaagact actatatcag aataactttg attagcctct aaaaggaagt ctctatatac
     7201 atgccgtaat tctttcgtac ttctcatcat tctgtttcct ccaattcctg acttaatctt
     7261 tctacaactg aagttaacat ttgtttctcc tctacagtag ggcgaagatg atgattggat
     7321 ttcatttctt ccagctcttg aaccccttga cctttaatag tatctaatac aatgcactta
     7381 ggtgatgaat tatttgactg ttttaattgg acaatccctt cataaatttc tctaatatct
     7441 gaacccttga ccctaatgga ttcaaatcca aatgctgaaa atttttctac gaaatcacct
     7501 ggattacaaa tatcctttgt aaaaccatct aattgttttt tgttatcatc aacaaataca
     7561 attaagttgg ataactgttg atgagaagca aactgtatag cctcccaaca ttgtccctca
     7621 tttaactcac catctccaac aatagcataa gtataaaagg gactctttct tattctctga
     7681 ccatatgcaa gtccagttgc aacactaatt ccttgtccta aagagcccgt tgtcatatct
     7741 atgcctggcg ttagatttct atcaggatga gacggtaatt tggttccatt tgtatttaaa
     7801 gaatataaga attctttgtc aaagaaacca ttcaaataga gtgtactgta tagagctggt
     7861 cctccatgac cttttgataa tatgaaataa tctctatctc gtgctgcaaa tatttctgga
     7921 gtcattggca ttatttcacc ataaagcact gctaaaactt ctacgataga cagacttcct
     7981 ccgtaatgtc cgaatccaag atgattcaat gttctaagag tatttaatcg gatgttagtc
     8041 gcaaattttc ttaacccatc ttctctattt ttacttaaaa tcatccctta ttcctccttt
     8101 gcagatggct ttttaataaa ggatactcca aacataactg ctagaataag aacaagacca
     8161 atcacaatac ctgcttgtga gccaaattga tttaacattc ctaaaataat tcctgataga
     8221 ccaaaatctg catctgagaa agttgatcct tggaaaccaa gtcctcccaa aactggcatt
     8281 aaaaagactg gaagaaaact gattaaaata ccttgtaaaa atgctccaat agtggcgcca
     8341 cgaacaccac cagatgcatt cccaatgaca cctgcagtcg ctccacagaa gaaatgaggc
     8401 acaacacctg gtaagataac aaccgttcct gaagcaatca taattgccat acttactaaa
     8461 ccaccaacaa aactagagat aaatccaatt agaactgcat tgggtgcata agtataaaca
     8521 atcggacaat ccaaagcagg ttttgaatta ggtacaagac gctctgaaat acctttaaag
     8581 gctggaacaa tttcgcccaa aataaggcga acacctgcta aaataacaaa tacccctgct
     8641 gcaaattgac ctgctaattg taaagcataa actagaccac ttgtaccact actgatttct
     8701 ttttctatat attctgaccc tgcaaagata gctacaataa tgtaaataac tgccatagat
     8761 aaagtgatac taacagtact atcacgtaaa aaagctaaac tctttggaaa tttaatgtcc
     8821 tctgttgatt ttgatttgtc accgataagg ctaccagtaa aaccactcaa ccaatatccc
     8881 aaagaactga aatgacctaa agccaccttg tcatttccag ttaattgaac catatatttt
     8941 tgcacaaatg ctggggaaat actcataata ataccgagtg ctaatcctcc tagtaagatg
     9001 agaggcaagc tagtaaagcc agcaactgat aaaatgaccg caatcataca tgccatatat
     9061 agagtgtggt gccctgttaa aaaaatatat ttaaatcgag taaaacgagc gattaagata
     9121 ttgaacacca tgcctgcaaa cataatcatt gcagtagctg agccatatgt tgttaaagct
     9181 acagctacaa ttgcttcatt attcggcaca acgccagata aatgaaaagc atgctcaaac
     9241 atggtaccaa atggatttaa agaattttgt acaattcctg caccaccaga tacaactaag
     9301 aaaccaacaa aggtcttaat tccaccttta ataatatcag gtaatttctt cttctgaaga
     9361 actaatccta aaattgcaat taaagctact aaaatagctg gtgtactaac aatatccaat
     9421 atgaacttca tcatgacgct agcctcctat ataagtcctt tttcttcaca aagtttagta
     9481 attaattctc gtagttcatc catatcaata atactattta agatacgaac atctccaaga
     9541 tgactagctg aatcagctag atcacgacca acaatccaaa tatcagctgc atttggatct
     9601 gctccaccta aatcataatg ttcaacttct acatccgaaa cattcaaatc actcaataca
     9661 gattcaatat tcatctgtac cataaaactt gaacctaatc ctgaaccaca agctgtacca
     9721 atttttaaca ttatctaatc ctcctgttta attatcattt taatgtcatc atagtttttt
     9781 gatgatatta aagtttgaac atgattttta tctcttaaaa ttgttgttaa atgtgacaaa
     9841 gcctttaaat gactctcatt atcaatggct gcaatacaaa tcaacaatct tacctcttgt
     9901 tctggattat ccaataaata aatcggttct tccaaaacta acattgacat tcctatttca
     9961 ttcacacctt catctggccg agcgtgagga attgctactc ccttccctaa attaataaaa
    10021 ggtccaaact cttctacttt ttgaatcatt gcctcagggt agttctcagt tatcttatct
    10081 tgatccaaaa gcggtttagc tgctaaacga atcgcctcct tccatcctaa tttttgcgaa
    10141 ctaacctgat aggtttcttt ggtaataagt tgttctagca ctggtacaat ttcctttcta
    10201 tcattttttt ggtaaagata attctttaac gccaatctta attccaattc ttgtgtaata
    10261 attccatatc ttttgacaat attcaggatt tgttcaatct caaaatctcc atactctaaa
    10321 ttcggaaaat cttttaacac tagttctact agttgtattg cttgctcttc agtcatcata
    10381 accgaaacta gataatttgg cttttctgtc tccaccttta tggtagaaaa aaccatatca
    10441 tagtcactac tagctttcac ctgtaaatca tcaatctttg aggttcctat aaactcaatt
    10501 tgaggaaata atgctaatag attctctttt aacatcaatg aagaactaac accattagga
    10561 caaatgattg ctgctttata gcatttttga ggcaaagtat ctgctttctt taaataacct
    10621 ccgaaatgga taacaaaata tgctgtttca ctatcaggta tgggattgtc aatagcgtcc
    10681 atcaagggca tcaaagaatc tttgactaat tcaaataaat caggataatg ttctttaaca
    10741 tgcaatacat attcatttga actaggtagg ccgaacttta atctatagta agccggtata
    10801 aggtggcggc gaagattttc tctcaatcct tccctttgtt taaaatgtaa caaagaaata
    10861 tcttccattc tacttataat agcctctgtt aattgattaa agtaaaccgg agcaacatct
    10921 acttcacctt caaagcaact tgataataaa actgtgatat agcgataatc atcctcagaa
    10981 aacaccgtat ctataattcc caaatcaacc actgtatcca ataaaatagt ggttatatct
    11041 tgaataacag gagatactaa tgtctctgaa agacatactc tttcaacatc cctttgatac
    11101 ctacacagaa tgaatactaa accgaaaagg caaactttta attgattaac aataggtact
    11161 agttgtagct tctcataata atctttaact acctgattta tcaaatcata agttaatgaa
    11221 tacccccaac tggataaaac ataatccaaa ccccaaatcc ctatggagga ttccagcaac
    11281 tcactaacca tttgaaaagc taagcggtgc ttattccact ctgaaccgtg taaagtataa
    11341 ccttttgctc tactgtaccc tagctccaaa tcattatcta acataatctt tcttaatgat
    11401 tgaatatcag ataaggttgt attcttactt actttcaaaa agtcttggta atgattattc
    11461 gatataaaat ctaatcggca aaaagtgtaa agatagatta aagctaagcg agtcgacttt
    11521 ggtaaaacca attcatccga cttaataata tctgtcaaag actgcttcgt acgatttgat
    11581 aaactatagc gaccttgttt tttatccagc actatccctt tattagctag ataaggcact
    11641 aaataatcta ttccttcttt gacttccttt ataggtaagc tcaccttaac agataattca
    11701 tataatgata gctcacaatg atccatcaaa gtcatcaaaa taactagtgc tctataatca
    11761 aacatttctc ttcctttcta actacaatta tagtgtaaaa attataagaa taaaagagta
    11821 tttgagcaca atataatctc accttttaaa agaaattatt gggctgaaag tttttagtga
    11881 ttattttcaa ctttctattg acttttaaaa acaaagtgat atcatttaga tatcaaataa
    11941 tgggaggtca ttcttatgac tgaaaaacta atcaattcaa aaccaaatgg tgtattcgca
    12001 ttgattctca ttgagttgac aatcgtactt ggtgtcttta tatttataat gggtgttggt
    12061 tcggaaaaca tttttggaat tattatcgga cctttactaa tcgtaattgc aggtctagct
    12121 catgctggtt taaaagttgt caaacctcag gaagctctgg ttctgacact ctttggtaat
    12181 tatacaggta ccatcaaaga acctggtttt tactttgtca atcccttcag cgtagcagtc
    12241 aaccctgcaa accacactcg acttggacaa agtggtgatg ttagcacaaa atctcctttt
    12301 ttaggagcta aatcatcaaa tgacaatgat gtaaatcttg aaattggcaa gaaacacatt
    12361 tccctcaaag tcatgacctt gagcaattct cgtcaaaaaa tcaatgattg cttaggaaac
    12421 cctgtagaaa tcggtatcgc ggtaacttgg agagttgtcg ataccgctaa ggcagtcttc
    12481 aacgttgata actacaaaga atatctttca ctgcaatgtg atagcgccct ccgtaatatt
    12541 gtccgcatct atccttacga tgtgtctcct aatgtggata ctacgggtga cgggcaagca
    12601 gatgaaggta gtctccgtgg ctctagcgaa attgttgcta accgtattcg tgaagaaatc
    12661 caaagtcgtg ttgaggatgc tggcttggaa atccttgaag cacgtatcac ttacctagct
    12721 tatgctccag aaattgctgc cgttatgctt caacgccaac aagcatctgc cattattgat
    12781 gcacgtaaga tgattgtaga tggtgctgta ggaatggttg aaatggcact agaacggctc
    12841 aatgaagggg aattggtaga acttgacgaa gaacgaaaag ctgccatggt ttcaaatctc
    12901 cttgtcgttc tttgtggcaa tcatgatgca caaccaattg tcaacacagg aagtctttac
    12961 taaagatggc tgaagctaaa aaaaagcaga tcccccttcg actctcaaca aagttatacg
    13021 ctgcactcgc atcatgggca gaagacgact ttcgttcagt caatggccaa atcgaatatc
    13081 tcctcacaga gtgtgtcaag caacggaaga aagacggaaa atacgtatca gaaaccattg
    13141 acgaaccatt tgagattgat atttaacacc ttctcctgtc tgccgtgtcg gataggagaa
    13201 ttttttcatc tttttttgtc aagtaacttt actttacaaa aaaaatgtgt tatcctagta
    13261 tggttgatga aaatcagtag attgaatcga atataaatac ctaaaggaga aatcaaaatg
    13321 gcagtacctg cacgtcgcac ttcaaaagcg aagaaaaaca aacgtcgtac acactacaaa
    13381 gtaacagctc catctgtaaa ctttgacgaa actactggag attactcacg ttctcaccgt
    13441 gtatcactta aaggatacta caaaggacgt aaaatcgcta aagctgcatc agctgaataa
    13501 tagaagggag ataccatgcg cgtaaatatt acacttgaac acaaagaatc tggtgaacgc
    13561 ttgtacctta cttctaaaaa caaacgtaac actccagacc gccttcaatt gaagaaatac
    13621 tcaccaaaac ttcgcaaaca cgttgtgttt acagaagtga agtaagcatt caatacgaat
    13681 caatacagaa gaaaaacgct tgatcagcgt tttttctttt tgttaatttc actatattgc
    13741 aagagaaatc attcgaatga ctacattttt tgaaataaga atacggattc ggacgattaa
    13801 aagtaagaga aactcaaatg taagttgggg ttcctttttt gtatattttt caaataacgc
    13861 ctctacacta tttgtagcaa attcaccaac tacagttgca tcttagttaa aataagttag
    13921 aatatgtaag tgagtaccag atataccaag acatcgtcac catctaaggt atattcaaaa
    13981 tacaaaagtt gaccaactag atttctgaat atccttatat atccattctt aaaattggtt
    14041 taaatagcgt agtcttttaa actagttttg agaatccaaa aaatcttcct acatatgtaa
    14101 gaagattttt tagttcagaa tgattagatt tagctaatgg atacctatcc tacccactca
    14161 ccgttagcat tgactcgata gccatcgggt gtagtcgtgt ttactaataa atctcctgaa
    14221 ttataggtat agtaccattt accagaaact gtaaaccaac cagtagccat tgaacctgat
    14281 tc
//
LOCUS       DAVHLA010000049        14065 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVHLA010000049 DAVHLA010000000
VERSION     DAVHLA010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14065)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14065)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14065
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.049"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(388..2079)
                     /locus_tag="VVO77_001772"
     CDS             complement(388..2079)
                     /locus_tag="VVO77_001772"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEU5693750.1"
                     /translation="MNTKELIASELSSIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            2215..2661
                     /gene="argR"
                     /locus_tag="VVO77_001773"
     CDS             2215..2661
                     /gene="argR"
                     /locus_tag="VVO77_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU5693751.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            2712..5246
                     /gene="mutS"
                     /locus_tag="VVO77_001774"
     CDS             2712..5246
                     /gene="mutS"
                     /locus_tag="VVO77_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEU5693752.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            5393..7087
                     /gene="patA"
                     /locus_tag="VVO77_001775"
     CDS             5393..7087
                     /gene="patA"
                     /locus_tag="VVO77_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HEU5693753.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEVIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQDGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(7417..7680)
                     /locus_tag="VVO77_001776"
                     /pseudo
     CDS             complement(7417..7680)
                     /locus_tag="VVO77_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            7874..9640
                     /gene="patB"
                     /locus_tag="VVO77_001777"
     CDS             7874..9640
                     /gene="patB"
                     /locus_tag="VVO77_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEU5693754.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTENKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            9779..10468
                     /locus_tag="VVO77_001778"
     CDS             9779..10468
                     /locus_tag="VVO77_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEU5693755.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQIGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            10472..10651
                     /locus_tag="VVO77_001779"
     CDS             10472..10651
                     /locus_tag="VVO77_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693756.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            10638..11987
                     /locus_tag="VVO77_001780"
     CDS             10638..11987
                     /locus_tag="VVO77_001780"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEU5693757.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            12111..13571
                     /locus_tag="VVO77_001781"
     CDS             12111..13571
                     /locus_tag="VVO77_001781"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEU5693758.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYSRHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWIIQKKDGYPTYNFAVAIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            13585..14019
                     /locus_tag="VVO77_001782"
     CDS             13585..14019
                     /locus_tag="VVO77_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEU5693759.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT         4109 a         2717 c         3165 g         4074 t
ORIGIN      
        1 aaatcatcgt aaacgcttcg gattacgaat gaatttgatt gctggtatta tcaatcatga
       61 actaggattc tagttttgca ggaagtctat tatttggtta ggtgaattag tgaagtgttt
      121 aggcaagtgt ctctggttac gacgtcatgg cctctaaatc gattatattt aggggtcatg
      181 actagtgaag cagttagcta gttcgcatat aagcggctag cgtctaacaa ttaggaactt
      241 tagttccaat aactttaaga ttacgacgtt ttaggacata aatcgatcat atttatgtcc
      301 taaaactagt gaagcgccta gccaaagtcc gaataggatt tggcgttagt tacttagatt
      361 gctttgcaat caagtaactt tggcgattta catcttctct ggcgcttcta ctccaagcaa
      421 gcgaagggct tctttgagaa cgactgcggt tgcgtagctg agggctagac ggctgtcgcg
      481 ttctgggctt tcatccaaga tacgtgtatg tgcatagtat ttgttaaagg attgagccag
      541 gctaattgca aatttagcaa tgatagaagg ttcaaagtta tctgccgcac ggttgataat
      601 acgtgggaag tcttgaatga gtttaatgat ttcccagctt tcagtatcat tcaagctata
      661 gttgccagct gtttctggtt tgaaatcggc tttgcgtaag atagattgga tacgagcgta
      721 ggcatattga acgtaaggtc cagtttcacc ctcgaaggat accatagctt ctaggtcgaa
      781 gtcgtatcca tttgtacggt cagttttgag gtcatagaat ttaatggctc caaccccaac
      841 agcatgtgct acttggtctt tgttttctag ttcaggattt ttagcctcga tttggacctt
      901 ggcacggcta acagcctctg caacagtagg ctctagcaag atgacattcc ctttacgagt
      961 agagagcttc ttcccttctt ttgtaaccag accaaaagga acgtgggtaa tgtcgtcact
     1021 ccaatcgtag cccatctctt gcaagacagc tttgagttgt ttaaagtggg cagattgctc
     1081 ttgaccaacg acgtagatag atttagcaaa ttggtattca tttttacggt agagggctgc
     1141 agccaagtca cgtgtgatat agagagttgc accatcagac ttcttgatga gggctggatg
     1201 ttcaattcca tatttctcaa gattcacaac ttgggcacct tctgattcaa gaagtagtcc
     1261 tttttcagaa agaatgtcta caactgcatc catcttatca ttgtagaagg cttctccgtt
     1321 atagctgtca aattcaacct tcaattcatt gtaaaggcgg ttaaattcca ctaaactttc
     1381 atcgcggaac cattgccaaa gagcgagagc ttcctcatct ccattttcaa gtttacggaa
     1441 ccattcgcgc gcttcttcat ccaagctagg gtcattttca gcttcagcgt tgatgcggac
     1501 atagagttta aggagttcat cgattggatg agcttttaca gcttcttcgt cgccccattt
     1561 tttgtaggca acaatcaaca tcccaaattg tttaccccag tctcccaaat ggttgacctt
     1621 gaccgtttga taaccgattt tttggaaaat atgtgacaag ctatctccga taacagttga
     1681 acgcaggtgg ccaatagaaa atggtttagc gatattcgga ctagacatgt cgataacaac
     1741 attttcttgt ttgccaatat tttggtcagc atagtgttct ttttcagtgg taacagcttg
     1801 caatacttga gcagaaatgg cagatttatc aaggaaaaag ttaacgtaag gtcctgttgc
     1861 gacaactttt tcaaaggctt ggctgttcat tttttcagcc agttcagccg caatcatttg
     1921 tggtgcttta cgttcgactt ttgcaagaga aaaagcaggg aaagcaatgt ctcccatttc
     1981 tgagttttta ggggtttcca gtaactttaa aatagcctct tggtccaggc tatcaatgat
     2041 gctagataat tcgctagcaa tcaattcttt tgtattcatt aagagctcct ttttggactt
     2101 ttctactatt ttatcacaat tttaaagaaa gaagaaaaaa tttttgaaat ctcctgtttt
     2161 tttggtataa tatggttata aatatagtta taaatatgca cgcaagagga ttttatgaga
     2221 aaaagagatc gtcatcagtt aataaaaaaa atgattactg aggagaaatt aagtacacaa
     2281 aaagaaattc aagatcggtt ggaggcgcac aatgtttgtg tgacgcagac aaccttgtct
     2341 cgtgatttgc gcgaaatcgg cttgaccaag gtcaagaaaa atgatatggt gtattatgta
     2401 ctagtaaatg agacagaaaa gattgatttg gtggaatttt tgtctcatca tttagaaggt
     2461 gttgcaagag cagagtttac cttggtgctt cataccaaat tgggagaagc ctctgttttg
     2521 gcaaatattg tagatgtaaa caaggatgaa tggattttag gaacagttgc tggtgccaat
     2581 accttattgg ttatttgtcg agatcagcac gttgccaaac tcatggaaga tcgtttgcta
     2641 gatttgatga aagataagta aggtcttggg agttgctctc aagacttatt tttgaaaagg
     2701 agagacagaa aatggcgata gaaaagttat cacccggcat gcaacagtat gtggatatta
     2761 aaaagcaata tccagatgct tttttgctct ttcggatggg tgatttttat gaattatttt
     2821 atgaggatgc ggtcaatgct gcgcagattc tggaaatttc cttaacgagt cgcaacaaga
     2881 atgccgacaa tccgatccct atggcgggtg ttccctatca ttctgcccaa cagtatatcg
     2941 atgtcttgat tgagcagggt tataaggtgg ctatcgcaga gcagatggaa gatcctaaac
     3001 aagcagttgg ggttgttaaa cgagaggttg ttcaggtcat tacgccaggg acagtggtcg
     3061 atagcagtaa gccggacagt cagaataatt ttttggtttc catagaccgc gaaggcaatc
     3121 aatttggcct agcttatatg gatttggtga cgggtgactt ttatgtgaca ggtcttttgg
     3181 atttcacgct ggtttgtggg gaaatccgta acctcaaggc tcgagaagtg gtgttgggtt
     3241 atgacttgtc tgaggaagaa gaacaaatcc tcagccgcca gatgaatctg gtactctctt
     3301 atgaaaaaga aagctttgaa gaccttcatt tattggattt gcgattggca acggtggagc
     3361 aaacggcatc tagtaagctg ctccagtatg ttcatcggac tcagatgagg gaattgaacc
     3421 acctcaaacc tgttatccgc tacgaaatta aggatttctt gcagatggat tatgcgacca
     3481 aggctagtct ggatttggtt gagaatgctc gctcaggtaa gaaacaaggc agtcttttct
     3541 ggcttttgga tgaaaccaaa acggctatgg ggatgcgtct cttgcgttct tggattcatc
     3601 gccccttgat tgataaggaa cgaatcgtcc aacgtcaaga agtagtgcag gtctttctcg
     3661 accatttctt tgagcgtagt gacttgacag acagtctcaa gggtgtttat gacattgagc
     3721 gcttggctag tcgtgtttct tttggcaaaa ccaatccaaa ggatctcttg cagttggcga
     3781 ctaccttgtc tagtgtgcca cggattcgtg cgattttaga agggatggag caacctactc
     3841 tagcctatct catcgcacaa ctggatgcaa tccctgagtt ggagagtttg attagcgcag
     3901 cgattgctcc tgaagctcct catgtgatta cagatggggg aattatccgg actggatttg
     3961 atgagacttt agacaagtat cgttgcgttc tcagagaagg gactagctgg attgctgaga
     4021 ttgaggctaa ggagcgagaa aactctggta tcagcacgct caagattgac tacaataaaa
     4081 aggatggcta ctattttcat gtgaccaatt cgcaactggg aaatgtgcca gcccactttt
     4141 tccgcaaggc gacgctgaaa aactcagaac gctttggaac cgaagaatta gcccgtatcg
     4201 agggagatat gcttgaggcg cgtgagaagt cagccaacct cgaatacgaa atatttatgc
     4261 gcattcgtga agaggtcggc aagtacatcc agcgtttaca agctctagcc caaggaattg
     4321 cgacggttga tgtcttacag agtctggcgg ttgtggctga aacccagcat ttgattcgac
     4381 ctgagtttgg tgacgattca caaattgata tccggaaagg gcgccatgct gtcgttgaaa
     4441 aggttatggg ggctcagacc tatattccaa atacgattca gatggcagaa gataccagta
     4501 ttcaactggt tacagggcca aacatgagtg ggaagtctac ctatatgcgt cagttagcca
     4561 tgacggcggt tatggcccag ctgggttcct atgttcctgc tgaaagcgcc catttaccga
     4621 tttttgatgc gatttttacc cgtatcggag cagcagatga cttggtttcg ggtcagtcaa
     4681 cctttatggt ggagatgatg gaggccaata atgccatttc gcatgcgacc aagaactctc
     4741 tcattctctt tgatgaattg ggacgtggaa ctgcaactta tgacgggatg gctcttgctc
     4801 agtccatcat cgaatatatc catgagcaca tcggagctaa gaccctcttt gcgacccact
     4861 accatgagtt gactagtctg gagtctagtt tacaacactt ggtcaatgtc cacgtggcaa
     4921 ctttggagca ggatgggcag gtcaccttcc ttcacaagat tgaaccggga ccagctgata
     4981 aatcctacgg tatccatgtt gccaagattg ctggcttgcc agcagacctt ttagcaaggg
     5041 cggataagat tttgactcag ctagagaatc aaggaacaga gagtcctcct cccatgagac
     5101 aaactagtgc tgtcactgaa cagatttcac tctttgatag ggcagaagag catcctatcc
     5161 tagcagaatt agctaaactg gatgtgtata atatgacacc tatgcaggtt atgaatgtct
     5221 tagtagagtt aaaacagaaa ctataaaacc aagactcact agttaatcta gctgtatcaa
     5281 ggagacttct ttgacaattc tccacttttt tgctagaata acatcacaca aacagaatga
     5341 aaaggagctg acgcattgtc gctccctttt gtctattttt taaggagaaa gtatgctgat
     5401 tcagaaaata aaaacctaca agtggcaggc cctggcttcg ctcctgatga caggcttgat
     5461 ggttgctagt tcacttctgc aaccgcgtta tctgcaggaa gtcttaggcg ccctccttac
     5521 tgggaaatat gaagttattt atagtatcgg ggcttggttg attggtgtgg ccgtagtcgg
     5581 tctagttgct ggtggactca atgttgtcct cgcagcctat attgcccaag gagtttcatc
     5641 cgaccttcgg gaggatgcct tccgtaaaat tcaaaccttt tcttatgctg atattgaaca
     5701 atttaatgcg ggaaatctag tcgttcgaat gacaaatgat atcaaccaga ttcagaacgt
     5761 tgtcatgatg accttccaaa ttcttttcag acttcccctc ttgttcatcg gttcgtttat
     5821 cctagcggtt caaaccttac cttctctgtg gtgggtgatt gttctcatgg tagtcttgat
     5881 ttttggtttg actgctgtca tgatgggaat gatggggcct cgttttgcta aatttcaaac
     5941 ccttcttgag cgcatcaatg ccattgccaa ggaaaattta cgtggcgttc gtgtggtcaa
     6001 gtcctttgtc caagaaaaag agcaatttgc taagtttaca gaggtctcag acgagcttct
     6061 tggtcaaaac ctttacattg gttatgcctt ttcagtagtg gaacccttta tgatgttggt
     6121 tggttacggg gcggtcttcc tctctatttg gctggtcgcg ggaatggttc agtcggatcc
     6181 gtctgttgtt ggttccatcg cttcttttgt taattaccta agccagatta tctttaccat
     6241 tgttatggtt ggatttttgg gaaattctgt cagccgtgcc atgatttcca tgcgtcgtat
     6301 tcgagaaatt cttgacgcag agccagctat gaccttcaag gatatcccag atgaagagtt
     6361 ggttggaagt cttagctttg aaaatgtgac ctttacctat ccaatggaca aggaaccgat
     6421 gctgaaagat gtgagcttta ctattgaacc tggtcaaatg gttggtgtag ttggagcgac
     6481 tggtgcagga aagtcaacct tggctcaatt gattccacgt ctctttgatc cacaggacgg
     6541 ggccattaaa atcggtggca aggatattcg agaagtgagt gaaggaaccc tgcgtaaaac
     6601 agtttccatc gttctccaac gtgccattct ttttagtgga acgattgcag ataacttgag
     6661 acaggggaag gggaatgcta ctctatttga aatggagcgc gcagccaata ttgcccaggc
     6721 tagtgaattc attcatcgta tggagaaaac ctttgaaagt ccagttgaag aacggggaac
     6781 caatttctct ggtggacaaa aacaaaggat gtcgattgcg cgtgggattg tcagcaatcc
     6841 acgtattctg atttttgacg attcgacctc agccttggat gccaaatcag agcgcttggt
     6901 gcaagaagct ttgaataagg acttgaaggg gacgacaacc attattattg ctcaaaaaat
     6961 tagctcggtt gtccatgcag acaagatctt ggttctaaat caaggacgat tgattggtca
     7021 aggcacgcat gcagacttgg ttgccaacaa tgccgtttac cgtgaaatct atgaaacaca
     7081 gaaatgaaag acaaactata agaaaagtca atagttttat ctaaactatt tcttatttca
     7141 atttgatgat ttggcgatga ttttagagca cggcaaaaag cccttgaaaa agtccatttt
     7201 ttcaaaggta atcctgtgtt aatttcagaa attacatcac tttttgttcg tcaaatggca
     7261 gctctttttt aggatataaa acagggttcg gataagtttt tttgcaaggt ggatgatggc
     7321 tacattgtaa tgttttcctt attctaactt agtcttaaga taggccttaa aagcaggtga
     7381 aaagcgagcg catgctttgg cagcttgtat gagtgcctac cgcagatgag gggaaccccg
     7441 tttgatcatt cttccagcta aatcaatctg acctgactga taaatagaag aatccagtcc
     7501 agcgaaagct tgtaattgag caggattatc aaaggcatga atattttgaa tctcggctaa
     7561 aatgaccgcc cctaaacgat tcccaatccc agtaaccgtc gtgatgaccg aatttaactc
     7621 agccatcaag tcattgacac atttttccgc cttgtcaatg agcctcttgt aatgtttgat
     7681 gttttcatta cacgagataa aacgtctatg cgttatcaaa ctcattacca attaaaacaa
     7741 atgtggttag atcctttcgg aaattgtcaa gcgattggag gaaatgaact aatccacagc
     7801 ggcttattcc aagtatacca cttgggcttt ggcagtagct aactgcgcta aatataatat
     7861 aaggaggagt aaaatgaaga cagttcaatt tttttggcat tattttaagg tctacaagtt
     7921 ctcatttgta gttgtcatcc tgatgattgt tctggcgact tttgcccaag ccctctttcc
     7981 agtcttttct ggacaagcgg tgacgcagct agccaattta gttcaagctt atcaaaatgg
     8041 caatccagaa cttgtatggc aaagcctatc aggaatcatg gtcaatcttg gcctgctggt
     8101 tttggttcta tttatctcta gtgtaatata catgtgtctc atgacgcgcg tgattgcaga
     8161 atcgaccaac gagatgcgca aaggtctctt tggtaagctt gctcagttga cggtttcttt
     8221 ctttgaccgt cgacaagatg gcgatatcct gtctcatttt accagtgatt tggataatat
     8281 cctccaagcc tttaacgaaa gcttgattca ggtcatgagc aatattgttt tatacattgg
     8341 tctgattctt gtcatgtttt cgagaaatgt gacgctggct ctcatcacca ttgccagcac
     8401 cccattggct ttccttatgc tgattttcat cgtgaaaatg gcacgcaaat acaccaacct
     8461 ccagcagaaa gaggtaggga agctcaacgc ctatatggat gagagcatct caggccaaaa
     8521 agccgtgatt gtgcaaggaa ttcaagagga tatgatggca ggatttcttg aacaaaatga
     8581 gcgcgtgcgc aaggcaacct ttaaaggaag aatgttctca ggaattcttt tccctgtcat
     8641 gaatgggatg agcctgatta atacagccat cgtcatcttt gctggttcgg ctgtactttt
     8701 gaatgataag tctattgaaa caagtacagc cctaggtttg attgttatgt ttgcacaatt
     8761 ttcacagcag tactaccagc ctattatcca agttgcagcg agttggggaa gccttcagtt
     8821 ggcctttact ggagctgaac gaattcagga aatgtttgat gcagaggagg aaatccgacc
     8881 tgaaaaggct ccaaccttca ctaagttgca agaaagtgtt gaaatcagtc atatcgattt
     8941 ttcatacttg cctgataaac ctattttgaa agatgtcagc atttctgccc ctaaaggcca
     9001 gatgacagca gttgttgggc cgacaggttc aggaaaaacg actattatga acctcatcaa
     9061 tcgcttttat gatgttgatg ctggtggtat ttattttgat ggtaaagaca ttcgtggcta
     9121 tgacttagat agtcttagaa gcaaggtggg aattgtattg caagattcgg tcttgtttag
     9181 cggaacgatt cgagacaata tccgatttgg tgtgccagat gctagtcagg aaatggttga
     9241 ggtagcagca aaagcaaccc acattcacga ctatatcgaa agtttgcctg ataagtacga
     9301 tactcttatt gatgatgacc agagcatctt ttcaacaggg cagaagcaat tgatttcaat
     9361 cgctcgaacc ctgatgacag atccagaagt tctcattctc gatgaagcaa cttcaaacgt
     9421 agatacggtg acagaaaaca agattcagca tgccatggag gtggttgtag caggtagaac
     9481 tagtttcgtc attgcccacc gcttgaaaac cattctcaat gcagatcaga ttattgtcct
     9541 taaagatgga gaagtcattg aacgtggtaa ccaccatgaa cttttgaagc taggtggctt
     9601 ttattcagaa ctctatcaca atcaatttgt tttcgaataa gaaagaagtt gtcctatgtg
     9661 ggcagctttt tcttgtccat aaaaaatgtt tatcacagcc ttaaaaaaaa catattagac
     9721 gaaagtcatt ttgagtgata tgataggact atcgttagca ttcgaaagga gaggcatcat
     9781 ggctagaacg gttgtaggag ttgctgcaaa tctatgtccc gtagacgcag aaggcaaaat
     9841 cattcattca tctgtatctt gtagattcgc agagatcatt cgtcaaatcg gtggtctccc
     9901 tttagtcatt cctgttggtg atgagtcagt tgtacgtgat tatgtggaaa tgattgacaa
     9961 actcattttg acaggaggcc aaaatgttca tcctcagttt tatggagaga aaaagaccgt
    10021 cgagagcgat gattacaatc tggtccgtga cgaatttgaa ttggcactct tgaaggaagc
    10081 gcttcgtcag aataaaccaa ttatggcaat ctgtcgcggt gtccaacttg tcaatgttgc
    10141 ctttggtgga accctcaatc aagaaatcga aggtcactgg caaggactac ctttcgggac
    10201 atctcactct attgagacag tagaaggaag cgtggtggct aagctatttg ggaaagaaag
    10261 tcaggtcaac tcagtccatc gtcaaagcat taaagatttg gcacctaatt tccgtgtaac
    10321 tgctattgat tcaagagacc aaactattga agcgattgag tctatcgacg agcaccgcat
    10381 tatcggttta cagtggcatc cagagtttct ggttaatgaa gaagatggca atttagaatt
    10441 atttgagtat ttattgaatg aactgtaacg attggaacat ctggtcgttc tttcttttat
    10501 tttttcaaaa tttttagaat gtggcatttt acgcaaacgt ttgaattctg ataaaaattg
    10561 gagaaattcg acaaaaaaac ttgaaaaaaa cgaaggtaag cgttatgata gaaaagaaga
    10621 aatattggag gaagaacatg tcacatatta aatttgatta ttcaaaagtt ttagacaaat
    10681 ttgttgcacc acatgaagtg gaatacatgc aatcacaagt aacagcagca gatgaattga
    10741 tccgtaaagg aactggtgct ggtagcgact tcttgggatg gttggacctt cctgaaaaat
    10801 acgatcgcga agaatttgac cgcatcttga aagctgctga gcaaatcaag tcagacagcg
    10861 atgttttggt tgtgatcggt attggtggat cttaccttgg tgcaaaagca gcaatcgact
    10921 tcttgaatca ccattttgct aacttgcaaa caaaagaaga acgcaaagct ccacaaatcc
    10981 tttacgcagg aaactcaatc tcatctactt accttgctga cttggtagag tatgttgcag
    11041 acaaagactt ctcagtaaac gtaatttcta aatcaggtac aacaactgaa ccagcgattg
    11101 ctttccgtgt ctttaaagaa ctcttggtta agaaatacgg tcaagaagaa gctaacaaac
    11161 gtatctatgc aacaactgac cgccaaaagg gtgctgttaa ggttgaagca gacgctaacg
    11221 gttggggaac atttgttgtt ccagatgata tcggtggacg cttctcagta ttgacagccg
    11281 ttggtttgct tccaatcgca gcatcaggag ctgacatcaa agctcttatg gaaggtgcga
    11341 atgcagctcg caaagactac acttcagaca aaatctctga aaacgaagct taccaatacg
    11401 cagctgttcg gaacatcctt tatcgtaaag gctatgcaac tgagatcttg gtaaactatg
    11461 agccatcact tcaatacttc tcagaatggt ggaaacaatt ggctggtgaa tcagaaggaa
    11521 aagaccaaaa aggtatctac ccaacttcag ccaacttctc aactgacttg cactcacttg
    11581 gtcaatttat ccaagaagga actcgtatca tgtttgaaac agttgtccgt gttgacaaac
    11641 ctcgtaaaaa cgtgcttatt cctactttgg aagaagacct tgacggactt ggttaccttc
    11701 aaggaaaaga cgttgacttt gtaaacaaaa aagcaactga cggtgttctt cttgcccaca
    11761 cagatggtga tgtaccaaac atgtatgtga ctcttccaga gcaagacgct ttcactcttg
    11821 gttacactat ctacttcttc gaattggcaa ttgccctttc aggttacttg aatgctatca
    11881 acccatttga ccaaccaggt gttgaagctt ataaacgtaa catgtttgcc cttcttggaa
    11941 aaccaggatt tgaagaattg agcaaagaac ttaacgcacg tctataatag aagaaaagag
    12001 tggtttgccc actcttttta ctctctttat ccatagaaat tggactcagc caagacttgt
    12061 gatataatat agaaagcaaa aaggcagacg cctagataat aggagaaact atgtcaaaag
    12121 atatccgcgt acgttacgca ccaagtccaa caggactact acacatcgga aatgctcgta
    12181 cagcattgtt taattacttg tattcgcgcc atcatggtgg aacatttctc atccgtatcg
    12241 aagatactga ccgtaaacgc catgtcgagg atggtgaacg ttcacaactt gaaaaccttc
    12301 gctggttagg catggattgg gatgaaagtc cagaatcaca tgagaattat cgccagtctg
    12361 agcgtttgga cttgtatcaa aaatacattg accaactatt agctgaagga aaagcctata
    12421 aatcttacgt tacagaagaa gagttggcag ctgaacgcga acgccaagaa gtagctggcg
    12481 aaacaccacg ctacatcaat gaataccttg gtatgagtga agaagaaaaa gcagcttaca
    12541 tcgcagaacg tgaagcagca gggatcatcc caactgttcg tttggctgtc aatgagtcag
    12601 gtatctacaa gtggcatgat atggtcaaag gcgatatcga atttgaaggt ggcaatatcg
    12661 gtggtgactg gattatccaa aagaaagacg gttacccaac ttacaacttt gccgttgcca
    12721 tcgatgacca tgatatgcaa atctctcatg ttatccgtgg agacgaccat attgctaaca
    12781 caccaaaaca gctcatggtt tatgaagcac ttggttggga agctccagag tttggtcaca
    12841 tgaccttgat tatcaactct gagactggta agaagttatc taaacgtgat actaatacac
    12901 ttcaatttat cgaagattac cgaaagaaag gttaccttcc agaagcagtc tttaacttta
    12961 ttgctcttct tggttggaac ccaggtggtg aagatgagat tttctctcgt gaagaactca
    13021 ttaaactttt tgatgaaaac cgcctcagca agtcaccagc agcctttgat cagaaaaaac
    13081 tagactggat gagcaatgat tatatcaaga atgcagacct tgaaaccatc tttgaaatgg
    13141 caaaaccatt cttagaggaa gcaggccgtt tgactgacaa ggctgaaaaa ttagttgagc
    13201 tctataaacc acaaatgaaa tcagtagatg agattatccc attgacagat cttttcttct
    13261 cagatttccc agaattgaca gaagcagagc gcgaagtcat gacgggtgaa acagttccaa
    13321 cagttcttga agcattcaaa gcaaaacttg aagcgatgac agatgataaa tttgtgacag
    13381 aaaatatctt cccacaaatt aaagcagttc aaaaagaaac aggtattaaa gggaaaaatc
    13441 ttttcatgcc tattcgtatc gcagtttcag gcgaaatgca tgggccagaa ttaccagata
    13501 caattttctt gcttggacgt gaaaaatcaa ttcagcatat cgaaaacatg ctaaaagaaa
    13561 tctctaaata aagaggatac aataatggac atctgggaaa agatgtacga agaagcacag
    13621 aaactataca atccacatga agtatcagac tttgtttatg ccaatcatgt tgtagctgca
    13681 gtagaagcag aagatggaca aatatttaca ggattctgta tggagggaac ctgtggtgtt
    13741 ttccatctct gcgcagaacg ggcggccctc ttcaatatgt accaattttc aggacaaact
    13801 aaggttaaga aagtattagc ctttcgagac aaaccacctt atggtggaag ttcagccatg
    13861 ccttgcggtg cttgtagaga attcctttta gagcttaatg ctgaaaataa agatgcagaa
    13921 ttcatgatgg actataatat aagaaaaaca gttaaagtcg cagaactaat cccttattgg
    13981 tggggagaag aacgtgcttc taagtttaat gagcgataga agagtcagta taattctggc
    14041 tttttttact ataagttgaa aaaat
//
LOCUS       DAVHLA010000050        14030 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVHLA010000050 DAVHLA010000000
VERSION     DAVHLA010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14030
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.050"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(23..316)
                     /locus_tag="VVO77_001783"
                     /pseudo
     CDS             complement(23..316)
                     /locus_tag="VVO77_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001167986.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
     gene            complement(482..707)
                     /locus_tag="VVO77_001784"
                     /pseudo
     CDS             complement(482..707)
                     /locus_tag="VVO77_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            1555..2427
                     /locus_tag="VVO77_001785"
     CDS             1555..2427
                     /locus_tag="VVO77_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEU5693760.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(2573..2917)
                     /locus_tag="VVO77_001786"
                     /pseudo
     CDS             complement(2573..2917)
                     /locus_tag="VVO77_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            3060..3371
                     /locus_tag="VVO77_001787"
     CDS             3060..3371
                     /locus_tag="VVO77_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693761.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEHPELYAVAQTSGEIPEKKREELRQIITTIFEQKMNKHSI
                     K"
     gene            3375..4091
                     /locus_tag="VVO77_001788"
                     /pseudo
     CDS             3375..4091
                     /locus_tag="VVO77_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
     gene            complement(4221..5036)
                     /locus_tag="VVO77_001789"
     CDS             complement(4221..5036)
                     /locus_tag="VVO77_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEU5693762.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(5033..5938)
                     /locus_tag="VVO77_001790"
     CDS             complement(5033..5938)
                     /locus_tag="VVO77_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEU5693763.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMLLAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
     gene            complement(6313..6396)
                     /locus_tag="VVO77_001791"
                     /pseudo
     CDS             complement(6313..6396)
                     /locus_tag="VVO77_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            6440..8569
                     /locus_tag="VVO77_001792"
     CDS             6440..8569
                     /locus_tag="VVO77_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEU5693764.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIADLEKEAEKFVCEGFATGKEALAGAVDI
                     LVEALSEDVTLRAMTYQEVLRHSKLTSQVKDESLDEKQVFQIYYNFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNINTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKRL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKQIDTEREKVNLSLLAPNETD"
     gene            8556..9005
                     /locus_tag="VVO77_001793"
     CDS             8556..9005
                     /locus_tag="VVO77_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEU5693765.1"
                     /translation="MKLTDYVKQVSLEDFGRSFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPIKLYRCQSCQQTYQRKRRIDTRRYRCGLCRGKLLLINQPED"
     gene            9064..9336
                     /locus_tag="VVO77_001794"
     CDS             9064..9336
                     /locus_tag="VVO77_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEU5693766.1"
                     /translation="MNSKFYKMRRNRMISGVLVGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(9384..9548)
                     /locus_tag="VVO77_001795"
     CDS             complement(9384..9548)
                     /locus_tag="VVO77_001795"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693767.1"
                     /translation="MDEAGEILLILFKNQSANYVNFTLPTKLQPAAGFLVCTLIFIEY
                     KSKKALNQAV"
     gene            complement(9690..9881)
                     /locus_tag="VVO77_001796"
     CDS             complement(9690..9881)
                     /locus_tag="VVO77_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693768.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            10309..11067
                     /locus_tag="VVO77_001797"
     CDS             10309..11067
                     /locus_tag="VVO77_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5693769.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFNEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            11069..13057
                     /locus_tag="VVO77_001798"
     CDS             11069..13057
                     /locus_tag="VVO77_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5693770.1"
                     /translation="MFRLTNKLAISNLIKNRKLYYPFALAVLLAVTITYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKKLGIYGMLGLEKRHL
                     ISMTFKELVLFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQMKVVITVLL
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKRGRFLPLQTILGSISLGIGYYLAL
                     TVTDPLTALTIFFLAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYSVKEKEVLRYSNFGIANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNEGVKEQKALTLNDHQFSVKEEFTKDFIVNHVPNQF
                     NILTADYNYLVVPDLQAFLNQFPDSDIYNQFYGGMNVSISEEEQLKVAEEYEKYLQKF
                     NAQLNTEGNYVYGSTLADASAQMSVLFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQIINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(13099..13743)
                     /locus_tag="VVO77_001799"
     CDS             complement(13099..13743)
                     /locus_tag="VVO77_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HEU5693771.1"
                     /translation="MLRAGVLDANNGIISIAGVVIGVASATTNIWIIFLSGFAAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQNGECKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSEYR
                     IPATVLIVGVALLLTGYTSARLGKAPARTAMIRNLAIGLLTMGVTFLLEQLFSI"
     gene            complement(13769..>14030)
                     /locus_tag="VVO77_001800"
     CDS             complement(13769..>14030)
                     /locus_tag="VVO77_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEU5693772.1"
                     /translation="DVFSEEHIYYAHPYASWERGTNENRNRLIRRWLPKGTKKMTPKE
                     VAFIEKWINNYPKKYLDYKSPREDFLMANLNLKFSVRNKSRN"
BASE COUNT         4297 a         2609 c         2873 g         4251 t
ORIGIN      
        1 aaataagata tgcacaaatt gattagaaag tcaaatgaat ttctacaaat gttttagcaa
       61 tcgtaatgta cttgtctaga ttcgatctga tatattttcg atttaatgat atggtattta
      121 aaacctccaa agtagcttac tccattcttt tacttacgtg agtgtagatg ttatttactg
      181 ttttagcgtt tttgtgttcc actctaacca ttatagcatt cttctcagct agtgtactaa
      241 ggagtgtgtg cctgaaaata tgggaactaa ggggctggtt tatcggtttc tctagtttag
      301 tatttgcctt ttgcaaagtg atcttaaatg cctttctcta aatttacata tcactattgt
      361 ttaacaaaat ctaatctatc ttaggtcact tattcttttt ttgaaatgta gaatgaactt
      421 tttcaaagtt tttcgaatct tttaaaatct gtttgtttta tatcgccatt ctcccccttt
      481 tttaattctc cctatatagc ctgacaactt tcccgatggt acgaatatgg ttgctttcgt
      541 ctaggtggat gtcggagtat tcgggattga gtttttttga ggtagccttg gcggagtttc
      601 ttgacatagt tagtgccgtc tacttggaag atgccgatgg tattatagtc aatctgtggg
      661 gtattcttga taaataggta gtcgctgttt cttatctttg gctccatgga cttgctgacg
      721 acataagcga ttgggtcgta gtcgtctggg ataatggaaa ctccataact aaatcgtcgt
      781 cctgcatcaa gcggctacct gcagagataa actacctaac acgagagtaa gtagtctgtc
      841 tgtagtcgtc cagtctgatg atttttacga tacttcgttt ttctgatcat acagttgcct
      901 ctcggcatag gtcagaactt taccttgtct gggtggtgcc cgttggtcgt agatagattg
      961 gatatcgcta ggagaatcct tttgaactgg aggaaagagg gcatcaatca agctactgaa
     1021 tactttaact aagtcaaata tagtattttt cttagtagac ctaacccttt tttcataatt
     1081 tctaatggtg tttttactta tacctatctt agtacccaat tcttattgag tccaaccatt
     1141 actagtctat attgttttat agttgattga gtttggaata gtacgctgta gctgctaaaa
     1201 catttctagg aattaatttg cctttcctaa tagagttgtt catatcttat ttcaatctac
     1261 tatatttttc acctctaaca atcgcaatct cttctttatc catgaacgaa aacgctttct
     1321 atctttgtaa gtaaagcatc acacgaaatc cacgaaaatg aaaacctttg ttgtgttttc
     1381 gtaaaaaatt tgttgacaga gcacgaaacg cctactataa ttaaatcaag tttaaggaaa
     1441 taacaaaaaa acaaatcgga gggaaagacg atgaacacat taaatgagaa agtaatcaat
     1501 atctgtaaag cagtagttaa agaaacttta atccaagaca tttaggagaa agaaatgaag
     1561 aaatcaagaa aattagccac attaggaatc tgttcagcct tgtttttagg cttggctgct
     1621 tgtcaacaac aacatgctac ttctgagggg acgaatcaaa ggcaaagcag ttcagcgaaa
     1681 gttccatgga aagcttcata caccaaccta aacaaccagg taagtacaga agaggtcaaa
     1741 tctctcttat cagctcactt ggatccaaat agtgttgatg cattttttaa tctcgttaat
     1801 gactataata ccattgtcgg ctcaactggc ttatcaggag atttcacttc ctttactcac
     1861 accgaatacg atgttgagaa aatcagtcat ctctggaatc aaaagaaggg cgatttcgtt
     1921 gggaccaact gccgtatcaa tagttattgt cttttgaaaa attcagtcac cattccaaag
     1981 cttgaaaaga atgaccaatt gcttttccta gataacgatg cgattgataa aggaaaggtc
     2041 tttgattcac aagataagga agagtttgat attctatttt cgagagttcc aactgaggca
     2101 actacagatg tcaaggttca cgctgaaaag atggaaacat tcttctcaca atttcaattc
     2161 aatgaaaaag ctcgaatgct gtctgtagtc ttgcacgaca atctggatgg cgagtatctg
     2221 tttgtaggtc acgttggggt cttagtacct gctgatgacg gtttcttatt tgtagagaaa
     2281 ttgactttcg aagagcccta ccaagcgatt aaatttgcta gtaaggaaga ttgctacaag
     2341 tatttaggca ccaagtatgc ggattataca ggcgagggac tggctaagcc ttttatcatg
     2401 gataatgata agtgggttaa actttaatag tgttatgata tgacagtaat cttaggattt
     2461 ttatttctat ttttgatgag ttggtgggtt atttcaatcg ttaatagcca gaaaccacgc
     2521 aaaaatgaaa catttattgg ctatatccaa agatacgata ttgatgggaa tggctatcaa
     2581 tcattaccgt gtcctcagaa ctgagaggag ttcttgaaat cgtaaaacta ctttgaacaa
     2641 gagttacttc aacccattgg ctccgacgga ttaagttgct ttcgtgaaca ccaaaatcag
     2701 ccgcaatttc ttcataagtg cggtattctc gcacatattg aagagtggcc ataagaaggt
     2761 cttctaggct taatttaggt tttcgtcccc cttttgtgtg tttaagttga taagcagttt
     2821 ttaatacagc taacatctct tcaaaagtgg tgcgctgaac accaacaaga catttaaatc
     2881 gtgcatcagt tagttgctta cttgcttcat cattcataga actactatac catattttgt
     2941 ttcgcaggaa gtctaatgct aaaatcttat cagtgagaag atttcttaaa gtttattctt
     3001 tgtagtttca tctgtattag tacataattt aacttagaga aaataggagg actaatcgaa
     3061 tggaattaaa agattttaca gaaaaagaac aggaaatgat taagaaaagg cttacaatgt
     3121 ctaatattag tgacaaagaa actactgaga agattctggc gctagtacca caagacttga
     3181 ttaagcgaat cccgtttttt gtcagaaaac atgctacaac acgtacgatt aaacgcattt
     3241 caattgaaca ccctgaactc tacgctgtag ctcaaacaag tggtgagatt ccagaaaaaa
     3301 aacgcgaaga attgcgtcag attatcacaa ctatctttga acaaaagatg aataagcata
     3361 gtattaagta gagaatgaaa aaatatttta ttggcggttt gggaagcaat gcctatcata
     3421 gcaaggattt tctttaagaa ctagattcgc aggtctattt tctaaatcca tatgaaaagc
     3481 atcttcgaga tgaaacagaa ttgaaatcat ggtttaaaaa tgagattgta gaggaagaat
     3541 ctatctgtct gataggtcat tctattggag gcgatttagc tcgttatttc gcatcggaat
     3601 ttgaagaagt aaagaaactg attcttttgg atggtggcta tctagattta gataagattt
     3661 tacctttgga tacagagtta gaggaaacta aaaattatat caaatctcaa attatttcgg
     3721 acttagatgt tcttacttct aaagaaaaat ctgaagcaaa gcattggtca gaaaatatgg
     3781 agaaagctgt aagacagtcc tatcactgga atgttgagta taatagatat gagttggcta
     3841 taaattatga aaatatagaa gcgatactcc gcctacggag aaaaatacaa gcttttaaga
     3901 gagaagtggg agataccttg tttattagtc ctcgctatcc taatgaagct acatggagag
     3961 aggaagccct aaaagaattg ccagactatt ttgatactat ttttttagaa aactttggcc
     4021 atgagcttta tactcaagca cctaaagaaa tcgctagtct aatgaatgag tggctcgctt
     4081 attttctatg agctacttgt attgctggaa atggtataag atgaaaatct acaagtcact
     4141 aattttcata taacaaaaaa acgaacaggc tctttttctg ttattcagaa gagaacttgt
     4201 tcgtttttat cttgattttc ttaaaaagct ctatatacat agggattttc tggtttatcg
     4261 actttggtaa agctgtcgat ttccaaggtt ggaaggtttt gtttgagttc tttatggtag
     4321 tgattgacca gttttccttt ggctgtaatc caggtgttgt tttcatactg ccgggtattg
     4381 cccttggtca gcaatccata gacaccagaa tctgcgatac agtggataat gccgaatcgg
     4441 aacagaaatt gactattggc atgactgggg tcgttataga caaagcctgt aaactggatt
     4501 gtcttgccct caaattcatc tggatagtcg tagatagcct ccatgacttc catatagttt
     4561 tcattagtga tctgaatact atcttgggat aagtatttat ccgccgccgt tcgcatttcc
     4621 ttttcatagg ctgattttga aaaataagaa ctagtatctg gtttcaaata ttggcttgta
     4681 gtcccttcac ttgtctgaat agctagatcc gttccttccg atagggggaa atgataacct
     4741 ttagcagaaa cggtctgaga atccaagcta acagttggga aagttaagcc gatgacaagt
     4801 ggaatagcca gaagagaaat actcgtcatc ttggccaatc ggctgttcag atgactgtgg
     4861 gttttgactt gcttcatcca gatatacaat tgaacaattg ccaagataaa ggaaagcacc
     4921 atggagatat aggccagata ggaatagtgc atgttgatgt actggtttag tttgcccgac
     4981 agatggaggt aaatagtcag ttcaaaatag ccagctaaaa ctaaaaatcg aatcatagga
     5041 tgactccaat caagagagaa taggctaaaa cgaccagagt cacaatcgta atgaagtgac
     5101 taataaatcg tgctttcaag taatttttca tcatgagaat atttttgata tccagcattg
     5161 ggccaatgac gagaaaggcc agaactggtg ccaaaccgaa actcgagagt agagaagcac
     5221 ctataaaggc atccgcctca ctacagagcg aaagaagaaa ggctaaaagc atcaagagca
     5281 ggatagcaaa aagaggagtc gcactgatag aggtcagaat ccgagtcgga acgtagacct
     5341 gtattataga agcaaagagg cagccaaata ccaaataacg ccccgtatca aaaaattcat
     5401 caatggcctg cacaaagact tgaaaaactt tttttgcaga actcaagtaa gaaaaatcat
     5461 gctcatgaca agccagacga ttttctttct gaatcggttc ttgccagaaa aatcctagaa
     5521 aaattcctag tattacagcc acaagaatgg aacccagagc tcgtaatagt gcgacatgga
     5581 aggagttgcc aaaggcagaa taggtcgcaa aaagaacaat gggattgata acaggtgctg
     5641 tcacaagaaa aggaacggcc gtgtaacttg gaaccttttt ttccagaaaa cgattgatga
     5701 tggggacgat tccacattca caagaaggga aaagtatacc gacaaaggtc ccaaaaaaga
     5761 ttctccccca acgatttcga gggagaaaat gataaacctt gtcaggtgtg atataaactt
     5821 caatcagccc tgagacaatg cttcctatca gaacgaaggg aagggcttca atgataatgg
     5881 agagaaaaat ggctccagtt tgaagtacac tagatgggag ttgttgaaaa gcagtcatct
     5941 agtttttctt ttctgctttg acttttttct ctttgtcatc agggaaagta acttgtttca
     6001 aatcagggag tttagcaaac tcttcaaaca tcttgtccaa gtcgtctcgt tttgtaaatt
     6061 tgacagccat aggtgtacct cgattctaaa ttctacctct attatactat tattttgcgg
     6121 aaaagggagt tttttaattt gttttcgata gttgatacac ttcgaaaatc tcttcaaacc
     6181 acgtcagctt cgccttaccg tagtacggtt actgacttcg tcagttctat ccacaacctc
     6241 aaaacagtgt tttgagctga cttcgtcagt cttatccaca acctcaaaac agtgttttga
     6301 gctgacttcg tcagtcttat ccacaacctc aaaacagtat tttgagcagc ctgcggctag
     6361 cttcctagtt tgctttttga ttttcattga gtatgaaaag gattggagaa agccttccag
     6421 cttgtggtat aatagattta tggataaaaa atatgaaaaa atctctcagg atttgggagt
     6481 gacgttaaag caaattgata ccgttctaag tttgacagct gaaggggcga ctattccctt
     6541 tatcgcgcgt tatcgcaagg acatgactgg tagtctggat gaggtggcga ttaaggctat
     6601 tattgatttg gataaaagtc tgacaaatct caatgaccgt aaggaagctg tcttagctaa
     6661 gattcaagaa caaggtaagt tgaccaagga attggaagaa gctatcttag ttgccgaaaa
     6721 attagcagac gttgaagaac tctatcttcc ttataaggaa aagcgtcgta ccaaggcaac
     6781 cattgcccgt gaagctggac tctttcctct tgctcgtttg attttgcaga atatagctga
     6841 cttagagaaa gaagctgaaa agttcgtctg tgaaggattt gcgactggta aggaagcttt
     6901 ggctggtgca gttgatatct tggtcgaagc cttatcggaa gatgtgacac tgcgtgctat
     6961 gacttatcag gaagtgctga gacactctaa actcacttct caagtcaagg atgaaagtct
     7021 tgatgaaaaa caggtttttc agatttatta taatttttca gagacagttg gaactatgca
     7081 aggctatcgt accttggctc tcaatcgtgg ggagaaactt ggtgtcttga agatcggttt
     7141 tgaacatgcg acggaccgta ttcttgcctt ctttgctact cgtttcaagg tgaaaaatgc
     7201 ttatattgat gaagttgttc agcaatccgt taagaaaaag gtcttgcctg ctattgagcg
     7261 tcgtattcgg acagaattaa ctgagaaagc tgaagaggga gctatccaac ttttttctga
     7321 caatctgcgc aatctcctct tggttgctcc attgaaaggg cgcgtggttc ttgggtttga
     7381 cccagccttt cgtacaggtg ccaagctagc tgtcgtggat gcaacaggaa aaatgctgac
     7441 aactcaggtc atctatcctg ttaaaccagc atcagctcgt caaatcgaag aagccaagaa
     7501 agatttagca gatttaattg gtcaatacgg tgtagagatt attgccattg gaaatggaac
     7561 ggccagtcgt gaaagtgaag cttttgtagc ggaagttctg aaagatttcc ctgaagtcag
     7621 ctatgttatc gttaatgaaa gtggtgcttc tgtctattct gccagcgaac ttgctcgtca
     7681 ggagtttcca gacttgaccg ttgaaaaacg ctctgccatt tctatcgccc gtcgtttgca
     7741 agatcctctt gcggaattgg tcaaaatcga tcctaagtca attggtgtcg gtcaatacca
     7801 acacgatgtc agtcagaaga aactatctga gagtctggac tttgtcgtgg atacggtggt
     7861 taaccaagtc ggtgtcaata tcaatacggc cagtccagct cttctttctc acgtggctgg
     7921 actcaataaa accatttctg aaaatattgt caaataccgt gaggaggaag gaaaaatcac
     7981 ttcacgctcc caaatcaaga aagttcctcg tttgggggct aaggcctttg aacaggcagc
     8041 tggtttcctt cgtatccctg aaagtagcaa tatccttgat aatacaggag ttcacccaga
     8101 aaattacgct gccgttaagg aactcttcaa acgcttggac attaaggacc tgaatgaaga
     8161 ggcccaaagc aaactcaagt cgctttcagt caaggaaatg gcgcaagagt tagaccttgg
     8221 tccagaaact cttaaagata tcattgcaga tcttctcaaa ccaggtcgag atttccgtga
     8281 ttcctttgat gctccagttc tccgtcaaga tgtcctagat atcaaggact tagtggttgg
     8341 acaaaagcta gaaggagtgg tgcgtaacgt tgttgatttc ggtgcttttg ttgatatcgg
     8401 aattcatgag gacggtctca tccatatttc ccatatgagt cgcaagttta tcaaacaccc
     8461 tagtcaagtg gtggcagttg gagatttggt gagcgtttgg gttaagcaaa ttgatactga
     8521 acgtgaaaaa gttaatctgt ctctcctagc tccaaatgaa actgactgat tacgtcaagc
     8581 aggtttcact agaagacttc ggcagatctt ttatccatca tgtccagtgg aataggcgtc
     8641 tacgttcgac aggtgggcga tttttcccca aagatgggca tttggatttt aatcccaagg
     8701 tttatcagga actggggttg gacgttttta ggaaaattgt ccgacatgaa ctctgtcatt
     8761 atcacctcta ttttcaaggg aaaggctatc aacataagga tcgagatttt aaggaactgt
     8821 tgaaagcagt ggatggatta cggtttgtac catccttgcc caatagtaac tccaagccaa
     8881 tcaagctcta tcgttgccaa tcctgccagc aaacttatca gcgtaagcga agaattgata
     8941 ccagacgcta tcgctgtgga ctttgtcgag gtaaattgct actaataaat cagcctgagg
     9001 actgatgaaa gccgagccta cccgtgatat actatgtcta acttagcaga aagaggaaat
     9061 atcatgaaca gtaaatttta taaaatgaga cgaaatcgca tgatttcagg agttttggta
     9121 ggcctgtcag acaagtggaa ctttgatgtt acccttgtac gttttctgtt tgccattttt
     9181 acagtcgcaa actttggact tggggtgatt atctatatca tcctagcttc tatcatgcca
     9241 accaaggaag aaatcgaagc agaaatgtac ggaacaggcc cacgtaaacg caaagaagct
     9301 caagccattg acgataatga aggctggttt tggtgaggtt ttacaaaaga tttggaatac
     9361 gcaaaaagct ttaaatcaat agtctaaact gcttgattta aagctttttt acttttatac
     9421 tcaataaaaa tcaaagtgca aactaggaag ccagccgcag gctgtaattt agtcggcaat
     9481 gtgaagttaa catagtttgc actttgattt ttgaatagta ttaataatat ttcgccagct
     9541 tcatccacaa actatagtgg attggaacta gaatagtaca cctctacttc taaaatattg
     9601 ttagaaatcg atttgactat cctgatcgat ttgtcctgtt tttatttcat tttattataa
     9661 aagcagtaat ttaaactcag ttttttaatc tatttttgct gctgagacaa tacatttttg
     9721 gaaaaatggt ggatgctgat aacaactgat aaccagcaaa taacataagc agtgccggta
     9781 aattctgtac cgataaagtg tgtgtgttca actaagagct gaccgatgaa tggagagagg
     9841 agatagagaa gtccgatgag tatatgttct ttgtgtttca ttaaagcgca ccttctttcc
     9901 ttataggttg aacgacttgc aagtgttaaa ttgaatggta tgttatctag gtaagcttac
     9961 tcaaatgata gttcccgctt cctccttttc aaagtaagcc ttttcacact tatgttttac
    10021 aactttaaaa ataggaaatc aaatcatttt ctaagtaatt ttgcttatat ttcacccaat
    10081 cttacaaaaa tgtaagatta aagtctcttt tgtaaggtta ggttatggca agcggtcttt
    10141 ttttgatgta aactagactc ataaagaaca aaggagtaac atcatgaaac aaatcttaca
    10201 taagaaaact agaaaaccaa gtcacaaaga aattgagcgc gttcagctgg gatgcactat
    10261 gatgcaagct acatttcatt tgatgggata ttaagaaagg agattctcat gacactttta
    10321 gatgtaaaac acgttcaaaa aatttataaa acacgttttc agggcaacca agtagaagcc
    10381 ctcaaggata ttcactttac cgtcgaaaag ggtgactacg ttgccatcat gggtgagtct
    10441 ggttctggta aatcaactct tctcaatatt ctagctatgc tggataaacc aagtcgtggt
    10501 caggtttact tgaatggaac tgacaccgca accattaaaa attcacaggc ctctagcttc
    10561 cgtcgtgaaa agttgggctt tgtcttccaa gactttaact tgctagatac tctatctgta
    10621 aaggacaata tcttgcttcc gcttgtcttg tcaagaagac ctattacaga gatgatgaag
    10681 aaattggtgg tgacagctga gaatctgggt attaaccaat tgcaagagaa gtacccttac
    10741 gagatttctg gtggtcagaa acagcgtgta gcagtagccc gcgccatcat cacagaacct
    10801 gaaattctcc ttgcggacga gccaacagga gcccttgatt ccaagtcatc tgcagcctta
    10861 cttgatgtct ttaatgaaat caatgagcgt gggcaaacca tcctcatggt aacccactca
    10921 acagcagctg ctagcagggc caagcgtgtt ctctttatca aagacggcat tctttacaac
    10981 caaatctacc gtggagagaa gacagagcgt cagatgttcc aagaaatctc tgataccttg
    11041 actgtcatgg caagcgaggt gaattagtat gtttcgatta accaataagt tagcgatatc
    11101 gaacctgatt aaaaaccgca aactctacta tccctttgca ctggctgttc tcttggcagt
    11161 caccatcacc tatctctttt actccctaac cttcaatcca aagattgcgg aaatccgtgg
    11221 aggaaccacc attcaagcaa cacttggatt tggtatgttt gtcgttaccc ttgcgtcagc
    11281 cattatcgtc ctctatgcca atagttttgt catgaaaaac cgttccaaga aactgggtat
    11341 atatggcatg ttaggcttgg agaagcgcca tctaatcagt atgaccttta aggagttagt
    11401 gctatttggg attctaactg ttggagcagg aatcggtatt ggagccttgt ttgacaagtt
    11461 gattttcgct ttcctactca aactgatgaa attgaaggtg gaactggtcg ctaccttcca
    11521 gatgaaagtt gtcattacag tacttcttgt cttcggtttg attttcctag gcctcatgtt
    11581 cctgaatgcc cttcgaatcg cccgtatgaa tgccctccag ctctcacgtg agaaagctag
    11641 cggagagaaa agaggtcgtt tcctacctct ccaaactatt cttggttcca taagtttagg
    11701 gattggctat tatcttgccc ttacggtaac cgatcctctt acagccctaa caattttctt
    11761 cctagctgtt ttgctggtta tctttggtac ttatctattg tttaatgcag ggattacagt
    11821 cttcctacaa atcttaaaga aaaacaagaa atactattac caacctaata acctcatatc
    11881 tgtttccaac ttgattttcc gtatgaagaa aaatgcggtt ggactagcaa ccatcgctat
    11941 tttgtcaaca atggttttgg taaccatgtc agcagcgaca agcattttca attccgcaga
    12001 aagctttaaa aaagttctaa atcctcatga ttttggggtt tcagggcaaa atgttgaaaa
    12061 agaagatttg gacaaactct tgagccagtt tgcaagtgac aaaggttata gtgtcaaaga
    12121 gaaagaagta cttcgttaca gtaactttgg tattgcaaat caagaaggaa ccaagttaac
    12181 tatttttgaa aaaggacaaa accgtgtcca acccaaaaca gttttcatgg tatttgacca
    12241 aaaagattat gaaaatatga ctggtcaaaa actgtctcta tcaggaaatg aggtcggact
    12301 ctttgcaaag aatgagggag ttaaagaaca gaaagctcta actctaaatg atcatcaatt
    12361 ttctgtcaaa gaagaattta ctaaagattt tattgtcaac catgttccaa atcagtttaa
    12421 tattttgact gctgattaca attaccttgt tgtacctgat ttacaagcct ttttgaacca
    12481 attcccagat tcggatatct ataatcagtt ttacggtggt atgaatgtaa gtatcagtga
    12541 agaagagcaa ctcaaagtcg ctgaagaata tgaaaaatac ttacaaaagt ttaatgctca
    12601 attaaacact gaaggtaact atgtgtatgg tagcactcta gcagatgcta gtgctcaaat
    12661 gagtgtcctc tttggcggtg tcttctttat tggtattttc ctatccatta tctttatggt
    12721 cggaaccgtt ctggtcatct actacaaaca aatttctgaa ggctatgaag accgtgaacg
    12781 ctttattatc ttgcagaaag tcggtttaga tcaaaagcaa atcaagcaaa tcatcaacaa
    12841 acaggtttta actgttttct tccttccttt gctttttgcc ttcatacatc tagcctttgc
    12901 ctaccatatg cttagcctga ttttaaaagt gattggtgta ctggatacga ctatgatgtt
    12961 gatcgtgacc ttgtctatct gcgctatctt cctcatcgcc tatgtgctga ttttcatgat
    13021 tacttcaaga agttatcgca agattgtgca aatgtaaaaa agatacctcg acttcaaaat
    13081 cgaggtattt cttgtattct aaatgctgaa aagttgttcg agcaggaagg taactcccat
    13141 ggtcaagaga ccaatagcta ggttccgaat catagctgtt ctagccggag cctttccaag
    13201 tctggcacta gtgtaaccag tgagaagaag ggccacaccg acaataagga cagtagcagg
    13261 gatgcgatat tcacttggga atatggtcac tgacagcatt ggaggcaaac ttctaaggaa
    13321 aaaggcaacg aagctagaaa tggcagcgtg ccaaggattg gtaaattctt catactcaat
    13381 cccatatttt tcctctacca gagccttgag tggattttta agaaagatct tattagtcaa
    13441 gagttgggca gaagttttgc attctccatt ttggatataa gcagcataga gggatttttt
    13501 ggctagttcc ctatcttggt ctagcaagag tttttctcgc gaaacggcag cttcctcggt
    13561 atcttttgga gttgaaacgg atacatattc tccaccagcc attgaaaagg caccagctaa
    13621 gatagccgca aaacctgata aaaagataat ccagatattg gtcgtggcac tggcaactcc
    13681 gataaccaca ccagcaatgg aaataattcc attgttagca tcaagaacac ccgcacgcag
    13741 gatatttaaa cgacctgcaa aatttgaatc aatttcgtga tttgtttctg acgctaaatt
    13801 tcaagttcaa gttagccatc aagaagtctt ctctgggtga cttgtagtcc aagtattttt
    13861 taggatagtt gttgatccac ttttcgatga atgcgacttc tttgggagtc attttcttgg
    13921 ttcccttagg taaccatcta cgaatgagcc tgttgcgatt ctcattagtt cccctttccc
    13981 aagaggcata ggggtgcgca taatagatgt gctcctcaga aaatacatca
//
LOCUS       DAVHLA010000051        13699 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVHLA010000051 DAVHLA010000000
VERSION     DAVHLA010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13699)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13699)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13699
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.051"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            76..1335
                     /locus_tag="VVO77_001801"
     CDS             76..1335
                     /locus_tag="VVO77_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEU5693773.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMSCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    1411..1546
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            1585..2085
                     /locus_tag="VVO77_001802"
     CDS             1585..2085
                     /locus_tag="VVO77_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEU5693774.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            2161..2529
                     /gene="rplL"
                     /locus_tag="VVO77_001803"
     CDS             2161..2529
                     /gene="rplL"
                     /locus_tag="VVO77_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEU5693775.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            2716..2886
                     /locus_tag="VVO77_001804"
     CDS             2716..2886
                     /locus_tag="VVO77_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693776.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            2886..3134
                     /locus_tag="VVO77_001805"
                     /pseudo
     CDS             2886..3134
                     /locus_tag="VVO77_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            3148..3488
                     /locus_tag="VVO77_001806"
                     /pseudo
     CDS             3148..3488
                     /locus_tag="VVO77_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812122.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3481..3861
                     /locus_tag="VVO77_001807"
     CDS             3481..3861
                     /locus_tag="VVO77_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEU5693777.1"
                     /translation="MIDLYLSKNRQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            3874..4017
                     /locus_tag="VVO77_001808"
     CDS             3874..4017
                     /locus_tag="VVO77_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693778.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRH"
     gene            4110..4697
                     /locus_tag="VVO77_001809"
     CDS             4110..4697
                     /locus_tag="VVO77_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU5693779.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGVEFVSLLIISLCFSLIHAQGSTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTIIAWCLYV
                     SLGMFLGLVRYKLDLWGSMGLHLVWSLLVYSLLLF"
     gene            4899..5036
                     /locus_tag="VVO77_001810"
     CDS             4899..5036
                     /locus_tag="VVO77_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HEU5693780.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            5326..6729
                     /locus_tag="VVO77_001811"
     CDS             5326..6729
                     /locus_tag="VVO77_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase"
                     /protein_id="HEU5693781.1"
                     /translation="MNNDEWVYQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICH
                     EMRIPFKHLSTEDKFIMRNGKLVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGP
                     YILSDKRWDEAPIYLRYGVFRPSRDDEKKVVIDELIVGDEVVKDERLPVFKIPKGIVP
                     PDFLNKWLDKKDKKQGDFPFIIDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLG
                     FDGTYSSERLASECKALKILNEWSEMPKIYWYGKIWEHTFLGIEHMKGVPLNRWVTNN
                     FPLYEVVDKTKDYLLRVSKIVEKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIID
                     WEQAVFSNDEKVVHKVAAPGFRAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNY
                     VSQTRIEGKKLFESLGYTREHIDYVESLLSYLDSKCPQIENISRKKVLKPMHEIRTIE
                     SEQDIQDFIIKAFLLVN"
     gene            6918..7536
                     /locus_tag="VVO77_001812"
                     /pseudo
     CDS             6918..7536
                     /locus_tag="VVO77_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656069.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            7551..8291
                     /locus_tag="VVO77_001813"
     CDS             7551..8291
                     /locus_tag="VVO77_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5693782.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            8294..9613
                     /locus_tag="VVO77_001814"
     CDS             8294..9613
                     /locus_tag="VVO77_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693783.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASLLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPFIQSCFIKLLSIIIFRNNFMFIVSKWNLLYRKPY
                     IKSISAAITGAILLISSFQMISQNILSQFQDDSDLELKVAFIVYVGAPILIVLANIIS
                     IAFLSSHQERIEIQQFEILGTSNYQMVKIKVGEAIFLTFVTSLIAFLLNIKIMALIYY
                     SLGDILIDDMNLLGLILPNFIVSIILFILIFITKSSYFIFKNAKIIS"
     gene            9747..9884
                     /locus_tag="VVO77_001815"
     CDS             9747..9884
                     /locus_tag="VVO77_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HEU5693784.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            10180..11531
                     /locus_tag="VVO77_001816"
     CDS             join(10180..10621,10621..11531)
                     /locus_tag="VVO77_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEU5693785.1"
                     /translation="MKLSYEDKVQIYELRKQGQSFKQLSKRFGVDVSGLKYMVKLIDR
                     YGIEIVKKGKNRHYSSKLKQEMMDKALLEGCSQRSISLDYALPNQGMLSFWPAQYKKN
                     GYTIVEKTRGRPAKMGRKRKKTWEEMTELERLQEENERLRTEVAYPKKVKRVRGKGRS
                     PRARKAETVREMVSGGFRLDFLLETARLARSTYYYQLKQLDGVDKDKEIKTEIQGIDN
                     EHKGNYGYRRIHLELRNRGFVVNHKKVQRLMRILGLTARIRRKRKYSSYQGEIGKKAE
                     NLIQRQFEASRPMEKCYTDVTEFAIPNSTQKLYLSPVLDGFNSEIIAYHLSTSPNLEQ
                     VKSMLEQAFTEKYYENTILHSDQGWQYQHDSYHRFLESKEIQASMSRKGNSPDNGMME
                     SFFGILKSEMFYGYEKNFRSLENLEQAIVDYIDYYNNKRIKVKLKGLSSVQYRTKSFG
                     "
     gene            complement(11766..12374)
                     /locus_tag="VVO77_001817"
     CDS             complement(11766..12374)
                     /locus_tag="VVO77_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001165927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HEU5693786.1"
                     /translation="MQIKFIDKVSNLIMLNLLYVASVVTVIAIGSGESALIATLIKIV
                     RHEESYPYRDFANSFFKDYWKNLGAALISNLPILILLFSLFFLPYIPLPIYIISILRH
                     IGVIYIILHLIATTFLIPLIGRYNNTLKNSLHNSIMLAYKHFFIAVLIRIIEIIPVLL
                     FFILQNQLLVWITLMIFILPSITKYANAFLYNFIFSKYEKLN"
     gene            12540..12710
                     /locus_tag="VVO77_001818"
                     /pseudo
     CDS             12540..12710
                     /locus_tag="VVO77_001818"
                     /inference="COORDINATES: protein motif:HMM:NF013577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
     gene            12699..13310
                     /locus_tag="VVO77_001819"
     CDS             12699..13310
                     /locus_tag="VVO77_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEU5693787.1"
                     /translation="MTKDILELESQKMSSDTFIDEIKNNYLSIVESTRKLIDGRQIEL
                     AIKLIREANQILMIGVGSSGNAAREFESSLLRIGIISKTVIDTHFQLMHTALLKDNDL
                     IIAFSLSGSTKEVEETLLNAKRKNVKIISITNYSSRNIAKLSDCVLLTSKKESYLEGG
                     SLMAKASQLFIIDVICTRLSLINYEDTICKKEEIASLLSNKVE"
BASE COUNT         4693 a         1934 c         2675 g         4397 t
ORIGIN      
        1 aaccacacct acggcaaagt gaatctgaag tggtttgaag agagtacaac ttgtctttta
       61 gaaaaggagc ctataatgaa agtctttcag catgtaaata tcgtgacttg tgatcaagat
      121 ttccatgttt atcttgatgg aatcttagca gtcaaggatt ctcaaatcgt ctatgtcggt
      181 caagataagc cagcgttttt agagcaagct gagcagatta tagactatca gggagcttgg
      241 attatgcctg gtttggtcaa ttgtcacacc cattctgcaa tgacaggtct gagagggatc
      301 cgagatgaca gcaatctcca tgaatggctc aatgactata tttggccagc agaatctgag
      361 tttactcccg acatgactac caatgcggtc aaagaagccc tgacagagat gctccagtca
      421 ggaacaacaa cctttaacga tatgtataat cccaatggtg tggatatcca gcaaatttat
      481 caggtggtga aaacttccaa gatgagttgt tatttttctc cgactctctt ttcttcagag
      541 acagaaacaa ctgctgagac tataagtaga actcgatcca tcatagacga aatcttaaaa
      601 tataaaaatc caaatttcaa ggttatggta gcacctcatt ctccgtatag ctgcagtaga
      661 gacttgctgg aagcgagttt ggaaatggca aaagagctaa atattccgct ccatgtccat
      721 gtggcggaga ccaaggagga gtcaggaatt atcctcaaac gatacggcaa acgccccctt
      781 gcttttcttg aagaactggg ttatttagat catccgtccg tatttgctca cggggtcgaa
      841 ttaaacgaga gagaaattga acgcttggca tcttctcaag tggctatcgc ccacaatcct
      901 atcagtaacc tcaaactggc atcaggaatt gctccaatta tccagctcca aaaagcggga
      961 gtagcagtcg gaattgcgac tgactcggtt gcttccaata acaatctaga tatgtttgag
     1021 gaaggaagga ctgcagctct tcttcagaag atgaaaagtg gggatgccag ccagtttcca
     1081 atcgaaacag ctctcaaggt actgacaatc gaaggggcta aggtccttgg aatggaaaat
     1141 cagataggaa gtctggaagt cggcaagcaa gcagattttc tggtcattca accacaaggg
     1201 aaaattcatc tccaacctca ggaaaatatg ctgtctcacc tggtttatgc agttaaatct
     1261 agtgatgtag atgatgttta tatcgccgga gaacaggttg ttaagcaagg tcaagtcctg
     1321 acagtagaac tttaaaagaa aaattacgaa aaattttaaa aaaagtttgc aaaaatcttg
     1381 cattcttttt ttgactatgc tatacttata tacggtttaa aaaaactgcc taagacagta
     1441 ggggagctcg actcataaat atcctaccga ggacaaaacg tatcatgtaa aaagaagcgt
     1501 attgtacttt cgtgtctagg tttgggcgcg tttttctttt tgaaaaattc cccaagcaaa
     1561 ataattacgg aggtgaacac actaatgagt gaagcaatta ttgctaaaaa agcggaacta
     1621 gttgacgtag tagctgaaaa aatgaaagct gctgcatcta tcgtcgttgt agacgctcgt
     1681 ggtttgacag ttgagcaaga tacagttctt cgtcgtgagc ttcgtggaag cgaagttgag
     1741 tataaagtta ttaaaaactc aatcttgcgt cgtgcagctg aaaaagctgg tcttgaagat
     1801 cttgcatctg tatttgttgg accatctgca gtagcatttt ctaatgaaga tgttatcgca
     1861 ccagcgaaaa tcttgaacga cttttctaaa aacgctgaag cacttgaaat taaaggtggt
     1921 gcaatcgaag gcgctgtcgc atctaaagaa gagattcttg cacttgcaac tcttccaaac
     1981 cgcgaaggac ttctttctat gctcctttct gtacttcaag cgccagtgcg caacgttgct
     2041 cttgcagtca aagcggttgc agaaagcaaa gaagacgcgg cttaatctta agctacacag
     2101 cgtagcctag ctacgaaaaa aactattata aaatttaaaa cttatttgga ggaaataaca
     2161 atggcattga acattgaaaa cattattgct gaaattaaag aagcttcaat ccttgaattg
     2221 aacgaccttg taaaagctat cgaagaagaa tttggtgtaa ctgcagctgc tcctgtagct
     2281 gttgctgcag ctgatgcagc tgatgctggt gctgctaaag attcattcga cgttgaattg
     2341 acatctgcag gcgacaaaaa agttggcgtt atcaaagttg tacgtgaaat cactggtctt
     2401 ggtcttaaag aagctaaaga acttgttgac ggtgcaccag cacttgttaa agaaggcgtt
     2461 gcaactgcag aagctgaaga aatcaaagct aaattggaag aagctggagc ttcagttact
     2521 cttaaataat agagtatcgc aatttgattg cggaatccct atttaccagt ctttgagagc
     2581 gataagcgat tgatagaaac tgataaattg atttggtttc ctgccaaaaa ttctttggca
     2641 ggatttttgt tttaataaac tttcgggggt agacactaga ttgtctaccc ctttttttgt
     2701 gtttcggagg taattatgca aaaggaagga cagtcatcac gtcaattcgt gaagagtcat
     2761 ctcatgacta tcatgggagt tgatattgta aaagcaactc agttagttga tgaaatggaa
     2821 caagtaggtt taatccgatt tgatgaattt ggaaatgttg gaattttagt cttggaggga
     2881 caataatgaa gcgtattacc gctaatcaat atcagacatc agagcgttat tataagctcc
     2941 ccaaactttt atttgagagt gaacggtata agaatatgaa actggaggtt aaggtggttt
     3001 actcagtttt aaaagatcgg ttggagttgt ctttgagcaa aggttggatt gatgaggatg
     3061 gggctattta tttgatttat tccaattcaa atttgatggc acttttaggc tgttcaaagt
     3121 caaaattact ctccatgtga gtttgaagtg atatttttag atgattacca taaaaaacat
     3181 aactacccac tattttacga atcctatctt caaaacgtta tggaattcct tgaaagtcaa
     3241 gacataaaga atggggttga tgcctttgta gatgatcatc aaaatctcgt ttttgtttta
     3301 tatggacaag gctatcgagc cgagggaaaa gagggaatac ttacaaccca agtaactgta
     3361 aaagcttatg atgaagacaa gaaaccgatt aacttcgcaa atttattaga ttccttaatt
     3421 tattagattc cttaatcgtg tcagaatatc aaatggaacc gaatctttgg gaggtctccc
     3481 atgattgatc tctatctaag taaaaataga caaagaaatc aacttctttt agatttcttc
     3541 caaaactatg gcatagaggt atcttgtcat tcagtttctg aaatgacaaa ggacaaatta
     3601 attgagatga tgagctattc ttcagattgt tttgagtttt tatctcccaa tttattacga
     3661 tttaagaacc gtgacaatct aagattaacg gatttcgttg agataatttt aaaaaatcct
     3721 gaactaacca tcagacttcc tcttgcggtt tcaaataagc gagtttatcc aagtctgaat
     3781 ttggaagagg ctagagctct attgccaaga gatacgaaac aattgattta catggcgcaa
     3841 acacattatt tatctaacta aaggagaagc aatatggctg aacgattttg ggagaacttg
     3901 tccattattt tggctgaaag aaatatcagc tggattgagt taaccagaaa aatgtttgcg
     3961 ggagagtttc actatccaag tgaattgaat cgtttgtatc aaaagattcg ccactagaag
     4021 atggaacaat gaatgcctca aagtccatgg gtagaaagga ttgtgcaggt attagattta
     4081 gattatgaag atttatttcg gaggtaacta tgaaaagaat aattccagtt tatatattcc
     4141 aacaagtaaa tgtcctattg gtatctctat acttattgaa atttctttgt atcggtgagt
     4201 taactatact acagattctc tatggttcgt cactcatttc ttttttatgg atgtatggcc
     4261 aacgcaaaca agcgcataag gtcaatatga aatctaggat gaaatggctt ggtgttgaat
     4321 ttgttagcct actgattata agtctatgtt ttagtctgat tcatgctcaa ggaagcacga
     4381 atcaagcaaa cttaattggc cttcaacatc aaattccttg gttttcattt ttattgttct
     4441 taatcaatgc gagtatggtt gaagaatttc tgtatcgaga aattttatgg aatttggtca
     4501 gaaaattaga tatcagagtt gctttgacaa gtgttttatt tgccttagca catcatccag
     4561 gaaccattat agcttggtgt ttgtatgtat cgctggggat gtttttaggg cttgtacgct
     4621 acaaattgga cttatggggc agtatggggc tacatttggt gtggagccta ctagtttata
     4681 gtttgctgct tttttaaaat aggtaacctg atttttaggt aacttctaaa actaacttcc
     4741 agttttggga gagagatgga agttactttg aaaagttacg gaaacattat tttctacgtg
     4801 acaacattgt atcattgctt gcattttact gctggagaga gtataatgaa ggtggataaa
     4861 gcacttaatc ccaaaaattt aaataggagg agttagctat ggcagaagaa gtattaaatc
     4921 ttcaattagt atctgttcaa gttgacgaaa cagatgaagt tgatggaatg cgatttagta
     4981 cattcagtac aaaccgttgc ggtaactgga gtgcttttag ttgggaaaat tgttaattca
     5041 tttaaattgt aaactttagg gattctctgg agttatggat ctcgttccaa tatgtgcacg
     5101 ttggaatgtc agtgcttata tggggggaat ccaaaggatt ctcccttttt attttaataa
     5161 gtctgtctag ctatagatat attaagtttg atagaatttc ttggagattt tgttatggat
     5221 tataatttca atttggagca tcctttcttt ttcactaata atgattatag tacagatact
     5281 agcataaagt actaagtaag tctgcctttt aattggcacg aagtaatgaa taatgatgag
     5341 tgggtttatc aataccctat tggaaaattt gttgaaagac aagggtggaa aatacacatt
     5401 agttcagagt ataatagttc acacgaattg ttacaagatg tagcaaaaat ttgccatgaa
     5461 atgcgaattc catttaaaca tcttagtaca gaagacaaat ttatcatgcg aaacgggaaa
     5521 ttggttagtc gaggattttc tggtaaattt attacatgtt atccaaatca aaatgaatta
     5581 gagtcggttt tgcaaaggtt agaaagtgcc ttaaagcaat ataatgggcc atatatttta
     5641 agcgataaac gttgggatga agcaccaata tatctgaggt atggtgtgtt taggccgtca
     5701 agggatgatg aaaagaaggt tgttattgat gaattaattg ttggcgatga agttgttaaa
     5761 gatgaacgtt taccagtatt taaaattcca aaaggtatag tgccccctga ctttttgaat
     5821 aaatggcttg acaagaaaga taaaaaacag ggagactttc cctttattat agataatgca
     5881 attagatttt caaacagtgg tgggatatat aatgctagac taaaagaaga tgggaaaaaa
     5941 ataattttaa aagaggctag accgtataca ggtctaggat ttgatggtac ttattcttca
     6001 gagagattag cttcggagtg caaagcacta aaaattctaa atgaatggag tgagatgcct
     6061 aaaatatact ggtacggtaa gatctgggag cacaccttct taggaattga acatatgaag
     6121 ggcgttccac taaatagatg ggttaccaat aattttcctt tatatgaagt tgttgataag
     6181 accaaagatt atctattgag agtttcaaag atagtagaaa aactcatcga tttaacgaat
     6241 aagtttcatt ctgaaaatgt atatcatcaa gatttacatt taggaaatat cttggttaag
     6301 gatgaagatg agattagtat aatagactgg gaacaggctg tcttttcgaa tgatgaaaaa
     6361 gttgtacata aagttgcagc ccctggtttt agagcatggc gagaaacact tcccagtgag
     6421 atagattggt atggtattag acaaatagct cattatttat acatgccact agtaactaca
     6481 tcggatttga catacaacta tgtaagtcaa accaggatag aaggaaaaaa actatttgag
     6541 tctttgggtt atacaagaga acatatagat tatgtagaaa gtttattgtc atatctagat
     6601 tctaaatgtc cacagattga gaatatttcc aggaaaaaag ttttaaaacc catgcatgag
     6661 attagaacta tcgagagtga gcaagatata caagatttta ttataaaagc ttttctttta
     6721 gtgaactgat aggtattttc ttagcaaacg ataaagtttt agggccgata caatcaattg
     6781 cctattcatt aaataagata aatacaacca aagatttaag gaaaccgttt ttaaaatact
     6841 taagtggaga gaagaatttt atagacgctg aacatgataa taacggactg tatacttcat
     6901 caatagatgt gatacacatg aaagatgttg tatattctat tacaccagaa aataaattaa
     6961 gtattgactt ctcatttaag tcaccattta gggtattatt aacaggaact tctggtagtg
     7021 ggaaaacaac gattttaaat ttaattaatg gttctttaaa gccacaaaaa ggttatgtaa
     7081 atttgttatc acatgggaaa aagagttcag attcaatacc aacagttgat cagacaccat
     7141 atatttttga cactactatt cgtgagaacg taactttatt tcaaaatgaa tatttttcag
     7201 atgatcagat aattgaggtg ttaaaaaagg taaatctata tgaagaatta gaaaagatag
     7261 atatactaaa ttatcaatgt ggtgaaaatg gtagtaattt gtctggaggt caaaaacaaa
     7321 aaatagcttt agctagagct ctgattagaa ataataaagt gtacttattt gacgaaatat
     7381 cagctaattt agataatgat aattcaaatt ccatacatga tattctgttc aatttaggta
     7441 tttcatttat tgaagtttca catcattatg acttaaatga caagagatac actgatatat
     7501 aaattggaaa atggaacact tttcaaaatt aagtgattgg aggcaagaat atggataaag
     7561 attatatatt aaaagtgaaa gggctgtatc atcaattttt actgggaaac aataaaacgt
     7621 tgcaagtgct gaaaaatgtt tctctttctg cttcgagagg agaatttata agtattctag
     7681 gaattagtgg ttctggaaag tcaactttat taaaatgtat ttctagtttg cttgaaccaa
     7741 caagtgggga agtaatttta aatggaatca acccctataa aatcagaaat gcaaaattgt
     7801 caagtataag acgtaacgaa gtatctttta tatttcaagc atacaattta ataccttccc
     7861 tgccggtaat agaaaatata gcacttcctt tgcgattatc acaaaaaaaa ttaactatta
     7921 aaaatgtaga aaacttactc aaaagaatga agtttaatgc tggcttaaac gattttgttg
     7981 gaactctgtc tggtggagaa caacagaagg ttgctatagc tagagcggtt attgctgata
     8041 gtgatataat atttgctgat gagccaactg gggctttaga cagcgtttct cgtgaagtaa
     8101 tttttgaatt attgagagag ttagtagggg cgggtaagtg tgtaattatg gtaacgcacg
     8161 atatagaatt ggcctcgaaa actgatcgtg cattaatatt gaaagatgga aaaattttca
     8221 aagaacttca tagacctagc ggggaagagt tgtataaaat cttagaggta caatcaacta
     8281 cggaggaata gagatgctca gattagttta ctatcaattt ttacataata agaaacaatg
     8341 gttaggcgtt tcaccagtaa tttttgtttc gagtttagtt atgggattgg ctgttaatgg
     8401 ggtaattaat gttgagaata attcgcaagt atttgtcgga cttccagatc ctaaaccaat
     8461 ttttatgttt ccgatagtat tcggaggagt aacattattc tttgtgctct ctaacataat
     8521 aaatatgttg gttgaaattt ttagagatga ttacgaactt ctggaggtgt tgggagcaag
     8581 tctccttcaa ctatcatttc ttgtgggggg acagattttt atcatttcct cgattattag
     8641 ttttattgca tatctatgct ctatatttgt tacgtcaaat tattattatt ttttacaata
     8701 ctttttcggg gaaaatatat tacctgatat ccaatttcaa acgagtgctg ttggatgtat
     8761 cattacagta gtgttgattt catttttagc ctttctaagt ggttgctttt atacgttcaa
     8821 gaagattaga aataggaaga gttctaaaat aaggcatgtt ctttcaatag taaaaagaat
     8881 actgctattg gctggtttta gtgttatctg gttgctttct ttgcaacaaa ttttccaaga
     8941 tagcacaatt ttagcgaagg cccagataat attcaatatt gtaatcttag atattgtgat
     9001 tatttatcaa ttatctcctt ttatacagtc atgttttatc aaactacttt ctataattat
     9061 atttagaaat aattttatgt tcattgtttc gaagtggaat ttactatatc gtaagcctta
     9121 tataaaatct atcagtgctg caattacagg agctatatta ctaatttcta gttttcaaat
     9181 gatttctcag aatatactat ctcaatttca agatgacagt gatttagagc taaaagtggc
     9241 atttattgtc tatgtaggag caccaatttt gatagtactt gcaaatatta tttcaattgc
     9301 atttttgtca tcgcatcaag aaaggattga gattcagcaa tttgaaattt taggaacttc
     9361 taattaccag atggttaaga ttaaagttgg tgaggctata tttttgacat ttgttacttc
     9421 attaattgca tttttactta acattaaaat tatggcttta atatactact ctttagggga
     9481 tattttaata gatgatatga atcttttggg gttaatactt ccaaatttta tagtgtctat
     9541 tattttattt attttaatat ttattactaa aagttcctat tttatcttta agaatgcaaa
     9601 aattatttct taaaaatttg taagttttcg ctatataaaa tagttaaatc tattttgtat
     9661 cattgcttgc attttactgg tggagagaat ataatgaggg tggataaagt acttaatccc
     9721 aaaaatttaa ataggaggag ctagctatgg cagaagaagt attaaatctt caattagtat
     9781 ctgttcaagt tgacgaaaca gatgaagttg atggaatgcg atttagtaca ttcagtacaa
     9841 accgttgcgg taactggagt gcttttagtt gggaaaattg ttaattcatt taaattgtaa
     9901 actttaggga ttctctgaag ttatggatgt cgttccaata tgtgcacgtt ggaatgttag
     9961 tgcttatatg gggggaacag aatcctctct tgattgaaga caagttagcc attaggctgg
    10021 tttgtctctt tgtcaactgt agtgggttga tataatagta ttagtgagtg ggataaaagt
    10081 ttcatttagt ttattcagta caaatttaac gggtcaagat ttattgaact gcaccccaat
    10141 agttagacag aaaaaatcta acttttgggg tgttttatta tgaaattgag ttatgaagat
    10201 aaagttcaga tctatgaact aagaaagcaa ggacaaagct tcaaacagct ttcaaaaaga
    10261 tttggtgtgg atgtttctgg tctaaagtac atggtgaaat taattgaccg ttatggcata
    10321 gaaatcgtta aaaaagggaa gaatcgtcac tattcttcta aattgaaaca agaaatgatg
    10381 gataaagcct tactggaagg ttgttcacaa agaagtatta gtcttgatta tgccctccca
    10441 aaccaaggaa tgctttcatt ttggccggca caatacaaga aaaacgggta tactattgtt
    10501 gagaaaacaa gagggagacc agctaaaatg ggacgtaaac ggaagaagac ttgggaagaa
    10561 atgacagaac tagaacgact ccaggaggag aatgaacgct tacggactga ggtggcctac
    10621 ctaaaaaagt taaaagagtt agaggaaagg gacgaagccc tagagcgaga aaggcagaga
    10681 cagttagaga aatggtttca ggaggatttc gactagattt tcttcttgaa acagcacgtt
    10741 tagctcgctc gacttactat tatcagttga aacaactgga tggggttgat aaagataaag
    10801 agattaaaac cgaaattcag ggcattgata atgaacataa aggcaactat ggctatcgtc
    10861 gaatccattt agaactaagg aatcgtggtt ttgtggtcaa tcataagaaa gttcaacggt
    10921 tgatgagaat tcttggttta acggctcgaa ttcgccgtaa acggaagtat tcttcctacc
    10981 aaggagagat tggcaagaaa gcagagaatc tcattcaacg ccagttcgaa gcatcgaggc
    11041 caatggaaaa gtgctataca gatgtgacag agtttgccat tccaaatagc acacagaaac
    11101 tctatttatc accagtttta gatggtttta acagtgaaat cattgcttat catctttcta
    11161 cttcgccaaa cttagaacaa gtgaagagta tgttagaaca ggcctttaca gagaaatact
    11221 atgagaatac gattctccat agtgaccaag gctggcaata ccaacacgat tcttatcatc
    11281 ggttcctaga gagtaaggaa attcaagcat ccatgtcacg caagggcaac agcccagaca
    11341 acggcatgat ggaatctttc tttggcattt taaaatccga aatgttttat ggctatgaga
    11401 agaactttag atctttagaa aaccttgaac aagctattgt ggactacatt gattactaca
    11461 acaacaaacg aattaaggta aaactaaaag gacttagttc tgtgcagtac agaactaaat
    11521 cctttggata aattatttgt ctaatttttt ggggtcagta cagtattaaa taccatgatc
    11581 ttatgcgttt tataataaaa aatctgttct tgttttattt ttagaaaatt tactaaagac
    11641 taaaaatatt atgaataatt taaaaaatag tcaggtcata tagttttttg aaattaaaat
    11701 tattttatcg ttgaaattag ttaaaaattt ttataaaatc aagatgcaag gctatgagat
    11761 gttctctagt ttaatttttc atacttcgag aatataaagt tatataaaaa tgcattagca
    11821 tattttgtta ttgagggaag tataaaaatc attaaagtta tccaaactag taattgattc
    11881 tgtaatataa agaagagtag aactgggata atttcaataa ttctaataag aacggcaata
    11941 aaaaaatgtt tataggctaa catgattgaa ttgtgtagag aattttttaa agtgttatta
    12001 tatctaccga ttaaaggaat tagaaatgtt gttgctatta aatgaagtat gatatatatt
    12061 actccaatat gtcgtaagat agaaatgata tatataggta atggtatgta gggtaggaag
    12121 aacaaactga ataataagat taaaattggt aaattagata ttaatgctgc tcctaaattt
    12181 ttccaataat ctttaaaaaa actgtttgcg aagtctctat agggatagga ttcctcgtgt
    12241 cgtacaattt ttattagagt tgctattagg gcactttcac ctgatccgat agcaataact
    12301 gttactactg acgctacata gagtagattt aacattataa gatttgaaac tttatcaata
    12361 aattttatct gcatctttaa ctcctgctgt ttttatactt ataatatcac atcatttgag
    12421 tttcatcaac tttgaataca ttaagaaaga atataactat gaggaaagga aaaaattatt
    12481 atgaataaat ccaaaaaata taaagaaaga attcattatg aatacgataa tcttactaaa
    12541 tcagagaaaa aattgctgac tatattttag ttagagatag tgaaatagtt tatgaaacgt
    12601 cttcagaaat tgttagtaaa gtaaaagttg gagagggaac tcttaatcga ttttgcaaaa
    12661 agattggata ctctggtttt caggaactaa aattaaaaat gacgaaagat atattagagt
    12721 tagaatctca aaaaatgagt agtgacacat ttattgatga aataaaaaat aattatttat
    12781 ctattgtgga aagtacaaga aaattaattg atggtagaca aatagaatta gctataaaat
    12841 taataagaga agcaaaccag attttaatga ttggtgtggg ttctagtgga aatgcggcta
    12901 gagaatttga gagtagtttg ttaagaattg gaataataag taagacggta attgataccc
    12961 attttcaact catgcatact gcgttattga aagataatga tttgataata gcgtttagtt
    13021 tatctggttc cacaaaagaa gttgaggaaa ctttattaaa cgcaaaaaga aaaaatgtta
    13081 aaattatttc aataacaaat tattcgtcca gaaatatagc aaaattatct gactgcgttc
    13141 ttttgacatc aaaaaaagaa tcttatttag agggtggtag tttaatggct aaggcttctc
    13201 aactattcat aattgatgta atatgcacta gactctcttt aataaattat gaagatacta
    13261 tatgtaaaaa agaagagatt gcttctttgc tgtcaaataa agtggaataa atcaataatt
    13321 tttaaatttt aataaaaatt ttttaaaact ttagcaaaaa aacgatccta aaagggtcgt
    13381 ttttttgcta aagttttaaa aataaacaat aattaagatt atagtgcgtt gaatctatat
    13441 taggacataa caattcttaa atcattgtta gaaattagtt tgaatttccc aatcaatttg
    13501 ttcgattttt acatcattgc attatatcat gtgactatta accttgtttt ctcctaaaat
    13561 tgattttctt cttttcttat cttgtccact cgaaacaagt attgtaagaa tttgattatt
    13621 tttgaaagta cttttaatat atttgagata gttaaaaaag atttgaaact aaattccaaa
    13681 ttagaaaaag acttgaaat
//
LOCUS       DAVHLA010000052        12864 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVHLA010000052 DAVHLA010000000
VERSION     DAVHLA010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12864)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12864)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12864
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.052"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(44..856)
                     /gene="folK"
                     /locus_tag="VVO77_001820"
     CDS             complement(44..856)
                     /gene="folK"
                     /locus_tag="VVO77_001820"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEU5693788.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQVNLKQAIDKLRARGIHILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(899..1453)
                     /gene="folE"
                     /locus_tag="VVO77_001821"
     CDS             complement(899..1453)
                     /gene="folE"
                     /locus_tag="VVO77_001821"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEU5693789.1"
                     /translation="MDTQKIEAAVKMIIEAVGEDANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            complement(1434..2756)
                     /locus_tag="VVO77_001822"
     CDS             complement(1434..2756)
                     /locus_tag="VVO77_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEU5693790.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALTVIDRIAEGKDSPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            complement(2758..3732)
                     /gene="folP"
                     /locus_tag="VVO77_001823"
     CDS             complement(2758..3732)
                     /gene="folP"
                     /locus_tag="VVO77_001823"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEU5693791.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGANLVNDITGLMGDEKMAHVVAEARAQVVIMFNPVMARPQHPSSLI
                     FPHFGFNQTFTVEELADFETLPIEDLMVAFFERALARAAEAGIAPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEESGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            complement(3827..4534)
                     /locus_tag="VVO77_001824"
     CDS             complement(3827..4534)
                     /locus_tag="VVO77_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU5693792.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVAGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            complement(4587..6005)
                     /locus_tag="VVO77_001825"
     CDS             complement(4587..6005)
                     /locus_tag="VVO77_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEU5693793.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            6195..7007
                     /locus_tag="VVO77_001826"
     CDS             6195..7007
                     /locus_tag="VVO77_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU5693794.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKRTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKEMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            7346..8365
                     /gene="adhP"
                     /locus_tag="VVO77_001827"
     CDS             7346..8365
                     /gene="adhP"
                     /locus_tag="VVO77_001827"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEU5693795.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKGKTDGGAHSAVVTAVSKVAFNQAVDSVRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVAPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            8599..9588
                     /gene="manX"
                     /locus_tag="VVO77_001828"
     CDS             8599..9588
                     /gene="manX"
                     /locus_tag="VVO77_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEU5693796.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQAAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            9616..10419
                     /locus_tag="VVO77_001829"
     CDS             9616..10419
                     /locus_tag="VVO77_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEU5693797.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            10443..11354
                     /locus_tag="VVO77_001830"
     CDS             10443..11354
                     /locus_tag="VVO77_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU5693798.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(11410..12744)
                     /gene="pepC"
                     /locus_tag="VVO77_001831"
     CDS             complement(11410..12744)
                     /gene="pepC"
                     /locus_tag="VVO77_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEU5693799.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
BASE COUNT         3721 a         2899 c         2578 g         3666 t
ORIGIN      
        1 aactctagcc ttcagttgca agtaactgaa aactagagtt tttctatttt ttcaaagcat
       61 catacaagtt gcggatcggt tgttttaata tcggatggat aaaatgaggc gcaatttcct
      121 gtaaggactc aaggacaaaa aggcgttccg ctatgtaagg atgaggcaat atgaggtcgt
      181 ctgtataaag gatctggtcc tccacaaaga gcaagtccaa atcaatcaaa cgaggtcccc
      241 aatgcacttc tctcacccgt cccagctctg actcaatggc taacaaggtt tctaacaagt
      301 cttgtgctgg tagccaggtt tccacctcaa ccacttgatt ggcaaagcta tcctgctcca
      361 ctccacccca aggctccgtc gctaagacac tggactcttt gagaatatgg atgccacgag
      421 ctcgcagttt gtcaatggct tgcttcaagt ttacttgttt atctcccata ttgcttccta
      481 gggcgataaa ggctcgttgc ttgcggcgat gaatggttac cgagcaagta tctagtgaca
      541 aatgcaccgg tgcccaaggt tttttcagtt ccaacttcat ttcttggaca agaggataag
      601 actcaaaggt acgttccacc agtttatagg ctaccgtttc aatcaaatct tcactcgttt
      661 cctgaaacca agtcgtccac tgctgacaca attctccgta atggacagag gctgttaaat
      721 ccaagtctgt agctgccttg gtcatatcat aggataggat ggctgaaacg acaaatttct
      781 gccccaattc tttctcacta ggaaaaagac catgataggc aaacatttcc aaatccttaa
      841 tctgcagttg atccataatg attcctttct agaaaaatcc gcttgaagcg gattcttttt
      901 atagccccat taaacgataa gcttggtcgc ggaggtcctt atctgtttca aatagaccac
      961 gagctactgt cgtcaaggtt gcagtgcctg gttttctaac accacgcata ctcatacaca
     1021 tatgttccgc ctcaatgaca acaaaggctc ctttagcacc tagatagtcc atcaaggcat
     1081 cggccacttc gatattcaaa cgttcttgaa tttgtggttt tttcgaataa acttcaaccg
     1141 tacgggctag cttagacaag cctgccacac gaccatctgg aatgtaggca atgtgcgctc
     1201 taccataaaa tggcaagaag tggtgttcac acatggtatg gaaaaagata tccttttcta
     1261 ccaccatatt atcgtcaata atttcaaagg attttgacaa atgttcctct gctgtttgac
     1321 caagacctga aaaaatctct tgatacatac gggctacacg agcaggtgtt tcctgcaaac
     1381 cctcgcgatt agcgtcctct cctacagcct cgataatcat ttttacagct gcttcaatct
     1441 tttgtgtatc cattctcgtt cttcctctcc atcagatagg ccctcacttg gctcaagaaa
     1501 tacaaggaac ctgtgacaat cctaactgtt tgtttctctt cttttttatc tgtcaaattc
     1561 tgctctagaa aatcatgcca atcttggtag ctgagatttc tagacttagc tgcctctttc
     1621 agcacgcttt catccgtcgc ccgactatcc gcaaaatgtg ttagagtaag ctcggtatct
     1681 ggcatggctc ccagcaagtc caacatatcc tccaaggcct tggttttgat acaagtgaag
     1741 aggatttcct tatgataatc cgcaaaacgt tcttgcaagg ttaccaacaa ggccttgata
     1801 gcatggggat tgtgggctcc atccaaaatc atcaagggat ctcttgacac gatttccaaa
     1861 cgccctggcc aacttgtttc ttccaaggct tgaccaagaa agtcattgct tgctagctct
     1921 cgaccatctt cttgacaaaa agtatcaagt aaagctatgg ccatcccagc attctctatt
     1981 tggtacaaac caagcaggct agtctggaag cgaccttgtc tgacagcact tgtatagtca
     2041 aagacttccc ctgtcaccac actttcttga tgacgaacct gataatctgt cccgtaggca
     2101 agtctcggcg aatctttccc ttccgcaatg cggtcaatca cagtcaaggc ttctggagca
     2161 atacgccctg ttaccaaggg catcccttgt ttgataatac ctgccttctg ctctgctatg
     2221 gcctccaagg tgtcaccaag tagggccaca tgatccaagc caatagttgt aattcctgtc
     2281 aaaatgggct gacagacatt ggtactatcc aaaagtccac ccatgccaac ttccatgatg
     2341 gccacatcta cttgctctga ggcaaagtag tcataggcca gggctgtgat aatctcaaac
     2401 tcggttgtgc cctgtaaatt ggcgaccgct tctccctcca gcaaagactg atagtctgcc
     2461 atgagagctt ctagcctcgc ttctgagatc gattccccat tgatgctaat ctggtctgtg
     2521 taatgaatga gatagggcga gctaaacacg ccaactctca gccctagctt ttctagcatc
     2581 tttttcaaaa aagcaatagt cgagcccttg ccgttagtcc ctccgatatg gaggaccttg
     2641 agtttgagat ggggattgcc acgcaaagct aacagttcca ccattcgttc caagccaaaa
     2701 tgcggttgat ccgtccggta gttagcaatc cactgattgt tttcaatttc tttcatctta
     2761 tttatattgc tttaaatcta aattttccgc ttcatcagcc agacgaatgg cagatgcaat
     2821 ttcaactgcc atcctgtgac tagctacgtc atgcacgcgc accacttcta caccctgtct
     2881 cgcagcgata ctagttacat gagccgaagc cgtgtcccga tttcggaaac caagctctgt
     2941 ctcaggattg acttcaaacc cactttcttc aaggatattg atgacaaatc gcttgcgcga
     3001 cactccgaga aagattggat agcccttctg atgtagttta tccagatccc gtaaaaggag
     3061 gagattttct ttcttggtca gaccaaagcc aattcctgga tccaacagga tattttctgg
     3121 tgcaatacca gcttctgccg ctctcgctag tgctcgttca aagaaagcca ccatcaagtc
     3181 ttcgattggc aatgtttcaa agtcagctaa ctcttctact gtaaaagttt gattaaatcc
     3241 aaaatgaggg aatatgagcg agctagggtg ttgaggtcgc gccataactg gattaaacat
     3301 gatgaccact tgcgctctcg cttcagctac cacatgagcc attttttcat cgcccatgag
     3361 accagtgata tcattaacta gattggcacc agcagccaaa gcagcctctg ctacttgact
     3421 cttccaagta tcaatagaga tgaggacatc actttccttg cgaatcgctt tgatcactgg
     3481 aacaacacgc tggatttcct cttctatctc aacatagcta ctgcccggcc gagtcgattc
     3541 tccgccgata tcgagcatac tggctccttc tgctatcaat ttacgagcct gctggagtgc
     3601 ctgctcaaga gcaaaaaatt gaccaccgtc cgaaaaggag tctggggtta cattgataat
     3661 tccgcaaata actgtctttg catgattggc tttacttgac atatcggtca ctccctcaag
     3721 gattttcatc atattatttt tctattttac cataaaaaga aaaagatgga cacgattgca
     3781 ttcatctttc cctagtagaa agaggtcggt ttctacataa aagcttttaa acagaaattc
     3841 ctaatgtccg actcataatc accacaagag ccaacaaaca gaaagcaatc ccattaacaa
     3901 tcatgtgaag caagatcgac atttccaaac gttgggtctt gtaggccgtc caagatagaa
     3961 ctgtcgacat acctccataa atcaataaag aaggtaaatt acttggttga tgcaataaag
     4021 caaacacaat cgtaccgact acaaatccca agttctcctt gcctcggaaa atctttttag
     4081 gaacaatccc acggcacaag atttcctcac aaatcggagc aagcaaggct agcaagaaga
     4141 aactggaaat caacgaacta ttttgaacca tatcgttaat ctgagactgg ttagctgttg
     4201 tcgtctcatt tgacagttgc aacaagatag aaccaagtat atttgacccg acaataacta
     4261 aataactcaa gcccaaacgt gccaaatctt tagctctaaa aaaagaaaaa ttaaaactag
     4321 ctaacttggt tttacgagct cccataataa atagagccag aaccacaatt gaaaggccag
     4381 caactatcag ccctgactgt agcagggcta cttcttttaa agtcaaaata gaggtaacca
     4441 ctaggggaac ctgatataaa aggacggcaa gtaaaaagac caaaatccag cctgcacgat
     4501 tcaacaattc tttccacata tttttctctt tcatcaccta tctcctttgt attaaaaaag
     4561 gggggaaatc cccctgggtc attctattat aaggccatgc tgatgtagtt aaggataaac
     4621 aaggcatcca aaatccaaat catggcatga acatctttaa cttgaccttt gacaagctta
     4681 gtcaaagtgt aagtcaagaa accaactgca atcccttgag tgatagagta gctgaatccc
     4741 ataaagatag atgtgaagaa ggcaggaact gcttcagaca tatcatccca atggatattt
     4801 ttcaagctac caagcatcat aatcccaacg ataatcaaga ttggagctgt agccgctgtt
     4861 ggtacgatcg ctagaagtgg gctaaagaag cttgaaatcg caaaacagat agctacaacc
     4921 aaggctgtca aaccagtacg tccacctgca ccgataccag cagcagactc aacataagtc
     4981 gttacgtttg aagtacctgc aatggcaccg actgtcgttc caatcaaatc agagtaaaga
     5041 gccttatcca atttggctga ttggtgattt tcaccatttg tcgctacaat accaactttt
     5101 tcacctgtac cgatcaaggt accaattgtg tcaaaaatat ctgtcaatga gaaggcaaga
     5161 atggccatca gagtttcagg caagcgagct gtatctgaaa ccaaagctcc caaaccttct
     5221 gaaccaagag ctgcaccaaa gattgtcttc aaatcttcaa aagctgcacc aacatggtta
     5281 ttagcaaaat cgatactaga caaatcaacc aaaccaactg caatagcaag aacagttgtt
     5341 gtcaagatag agagaataat tcccccttta atccctttga tgacaaagaa gatagtaatg
     5401 gcaagtcctg caagagccac taaaacagct ggattattaa agctgaccaa tcctggaact
     5461 gctgaagagt ttgctgcaat cgttgcttga gctttgtcag ccccttctcc tacaacagta
     5521 tagttgcctg gatcaatcgt gaatttcaaa agtccagcat tcttaatccc tacataggca
     5581 aggaagacac cgataccagc tgaaatagct gagcgaagag cattgggaat cgattcaatg
     5641 atcattttac gaacatttgt caaggtaata atcaatgaaa taatcccaca gatgaagacc
     5701 atagctaggg cttcttgcca agaataacca agcccgaata caactgtaaa ggtaaagaag
     5761 gcattgagtc ccatacctgg cgcttgggca taaggtaagt tagcataaaa agccatcatc
     5821 aaggtacccg ctactgcacc aataatcgtc gctaggaaga cgccctgagc aggcattcct
     5881 gtttgtgaaa gtatttgtgg gtttacaaag agaatatagc tcattgcaaa gaaagttgtt
     5941 aaaccagcga gaacctctgt acgaacgtct gtaccgttct cttttagttt aaataatttg
     6001 tccatcatca atctcctttt aatttttacg aacaataata gaattatatc atttatcatt
     6061 cactttttca atgtatttgt ttgatttgtt taagaaatta atccaatttc attttttgtt
     6121 tggaatctgc ttttctgcct gctttctgtt ataatagaag acatcttatc tgaaaacaca
     6181 ctagaaaggt ccatatgacg aaaaaaatta ttgcagttga cctggatgga accctgctca
     6241 actcagacag tcaaatttct gactttacca aaagaaccat caaaaaagtt gctgaaaaag
     6301 gccatcaggt tattattacg acaggtcgcc cttaccgtat gtcaaaagat ttttaccgtg
     6361 aactgggctt agacactcct atgattaact tcaacggatc ccttactcat ttaccagacc
     6421 aagtttggga ttttgaaaag tgtttgactg tagacaaaaa atatctgcta gatatggttc
     6481 aacgttcaga ggacattcaa gccgatttta tcgctggaga atatcgtaaa aaattctaca
     6541 ttacaaatcc caatgaagaa attgccaatc ccaaactatt tggtgtagaa gctttccagc
     6601 ctgaagatca attccagcct gaattggtga ccaaggaccc taactgtatc ctcttgcaga
     6661 ccagagccag tgacaaatat gccttggcaa aagaaatgaa cgccttctac cagcatcaac
     6721 tttctatcaa tacctgggga ggtccgctca atatccttga atgtacccca aaaggtgtca
     6781 acaaggcctt tgctttggac tacttgctca agataatgaa tcgtgacaaa aaagatttga
     6841 ttgcctttgg agatgaacac aatgataccg aaatgctcgc ttttgctggg aagggttatg
     6901 ccatgaaaaa tgccaatcca gagctactcc cttatgcaga tgagcaaatt tcccttacca
     6961 acgaccaaga tggggttgcc aaaaccctac aagacttatt cttataacct atactgatac
     7021 tcaatgagaa tcaaagagca aactaggaag ctagccgtag gttgctcaaa gcactgcttt
     7081 gaggttgtag atgaagctga cgtggtttga agagattttc gaagagtatg accagcttgc
     7141 aagctggtct ttgtgctctt ttcacagtct catcaaccag ttaatcgatt gttctacttt
     7201 ttgtctccaa aaccttggaa aaggctttct tttgtgatat acttcacata taaatacaag
     7261 agagctcgtc acactcgact ctgttgacaa aaaatcaatc cagtcccgtt gtccctgttc
     7321 tcggtcaata tcaaggagga tagctatgaa agctgttgtt gtaaatccag aaagcactgg
     7381 tgttgctatt gaagaaaaag tactccgtcc acttgaaact ggggaagcac ttgtagaagt
     7441 tgaatactgt ggtgtttgcc acaccgacct ccacgttgct catggtgact ttggtcaagt
     7501 cccaggacgt gttcttgggc acgaaggtat cggtatcgtt aaagagattg ctccagatgt
     7561 gaaaagcctt aaagtcggtg accgcgtcag cgttgcttgg ttctttgaag gatgtggcac
     7621 ttgcgaatac tgtacaactg gtcgcgaaac cctttgccgt acagtgaaaa atgctggcta
     7681 ctcagtagac ggtggtatgg ctgaacaatg tatcgtaact gctgactatg ctgtcaaggt
     7741 tcctgacgga cttgatccag cccaagcttc ttctatcaca tgtgctggag taacaaccta
     7801 taaagctatc aaagaagcaa aagttgaacc aggccaatgg gttgttcttt acggtgctgg
     7861 tggacttggt aacctcgctg ttcaatacgc taaaaaagta ttcaatgctc atgttatcgc
     7921 agtcgatatc aacaatgaca aacttgccct tgcaaaagaa gtaggcgctg acattgtgat
     7981 taacggcctc gaagttgaag atgtagctgg actcattaaa ggaaaaactg atggaggagc
     8041 tcattcagct gtcgtaactg ctgtgtctaa agttgccttc aaccaggctg ttgactccgt
     8101 tcgtgctggt ggtcgcgtcg tcgctgttgg tcttccttct gaaatgatgg aactcagtat
     8161 cgttaaaaca gtcctcgatg gaatccaagt catcggttct cttgtcggaa ctcgtaaaga
     8221 cttagaagaa gccttccaat ttggtgcaga aggtctggta gccccagttg ttcaaaaacg
     8281 tccagtagaa gatgctgttg ccattttcga cgaaatggaa aaaggtcaaa tccaaggacg
     8341 tatggtactc gacttcaccc actaatctaa tagaaaccta ttttaaaagt tggaagcttc
     8401 ttctaacttt tttatattaa atttttaaat aagaattcaa gattactcct taaaaactca
     8461 acatatcaac atataaaaat aaaaattttt taatttttta tgataaatag ttgctttttt
     8521 tatgaaaacg gtttatactt aaacagtctt aaagttttct taaatgaaaa ctaaaacaaa
     8581 aaaggaggaa tgacaataat gagtatcgga atcattattg cgagccacgg cgaatttgct
     8641 gcgggtattc atcagtcagg atctatgatc tttggtgaac aagaaaaggt tcaagttgtg
     8701 acctttatgc caaatgaagg tcctgatgat ctatacgcta agtttaataa cgctgttgct
     8761 gcatttgacg cagaagatga ggttctagtt ttggctgacc tttggagtgg ttctccattt
     8821 aaccaagcta gtcgcgtgat gggagaaaat cctgagcgta agtttgccat catcacagga
     8881 cttaacttac cgatgttgat tcaagcctac acagagcgcc tcatggacgc tgctgcaggt
     8941 gtagaaaaag tcgctgctaa tatcattaaa gaagccaagg atggcatcaa agctcttcca
     9001 gaagagctaa atccagttga agaagttgca agcgctgcag ctgctccagt tgcccaagct
     9061 gctatcccag aaggaactgt tatcggagac ggtaaattga aaatcaatct tgcccgtctt
     9121 gacacacgtc tacttcacgg tcaggttgca actgcttgga ctccagattc aaaagcaaat
     9181 cgtatcatcg ttgcttcaga taacgtggct aaagacgacc ttcgtaaaga attgattaaa
     9241 caagcagctc caggtaatgt caaggctaac gtggttccaa ttcaaaaact gattgagatt
     9301 tcaaaagacc cacgttttgg agaaacacat gcccttatct tgtttgaaac acctcaagat
     9361 gcccttcgtg ccatcgaagg cggcgtgcca atcaagactc ttaacgttgg ttctatggct
     9421 cactcaacag gtaaaacatt ggtcaatacc gttttgtcta tggacaaaga agatgttgcg
     9481 acatttgaaa aaatgcgtga cttgggtgtt gaatttgatg tccgtaaagt accaaatgat
     9541 tctaaaaaag atttgtttga cttgattaac aaagccaatg tcaaataagc cattatttat
     9601 gaaaggattt taaacatgtc tattatttct atggttttag tagtcgttgt agccttcttt
     9661 gcaggtcttg aaggcatcct cgaccagttc caatttcacc aaccacttgt agcctgtacc
     9721 cttattgggc ttgtaacagg tcacttggaa gcagggatta tcctcggtgg atcgcttcaa
     9781 atgattgccc ttggttggtc aaatatcggt gctgctatcg ctcctgatgc tgcacttgct
     9841 tctgtcgctg ctgccattat catggttctt ggtggtgact ttaccaagac tggtatcggt
     9901 gttgcccaag cggttgctat ccctcttgcc gtagctggac ttttcttgac aatgattgtt
     9961 cgtacaattt cagttggttt ggttcatact gcagatgctg ccgctaaaaa aggtgacttc
    10021 ggcgctgtgg agcgtgcgca tttcattgcg ctactcttcc aaggacttcg tatcgcgctt
    10081 cctgcagctc ttctccttat ggtaccaact gaaactgtac aaagtatcct tagtgccatg
    10141 ccagactggc tcaaagatgg tatggctatc ggtggtggta tggtcgttgc cgttggttac
    10201 gccatggtta tcaacatgat ggcaactcgt gaagtatggc cattcttcgc tcttggtttc
    10261 gttctcgctg ctgtgtcaga tattactcta atcggattcg gtgctatcgg tgttgctatc
    10321 gctcttatct accttcacct ttctaaaact ggtggaaatg gtggcggagg agccgcaact
    10381 tctaacgacc caatcggcga tatcctagaa gactactaag ataagaaagg actgaaaaca
    10441 tcatgactga aaaacttcaa ttaactaaat cagatcgtaa aaaagtttgg tggcgttcaa
    10501 ccttcttaca agggtcttgg aactttgaac ggatgcaaaa cttgggctgg gcttatacac
    10561 tcattccagc tatcaaaaaa ctctatacta aaaaagaaga tcaaatcgct gctcttgagc
    10621 gtcaccttga gttcttcaac actcatccat acgtagctgc tccagtcatg ggggttactc
    10681 ttgcgcttga agaagaacgt gctaacggtg tggaaatcga tgacgctgct atccaagggg
    10741 tcaaaatcgg tatgatggga cctcttgctg gtatcggtga cccagtattc tggtttacag
    10801 tacgcccaat ccttggatct ctcggtgctt cacttgccct tactggcaat atcttgggtc
    10861 cactcctctt ctttgttgca tggaacttga ttcgtatgtc attcttgtgg tatgttcaag
    10921 agattggata caaggctgga tcagaaatca ctaaagatat gtctggtggt atccttcaag
    10981 atatcactaa aggagcttct atccttggga tgttcattct tgctgtcctt gttcaacgct
    11041 gggtaaatat taaatttgct ttcgatgttt ctaaagttca actagatgaa aaggcttata
    11101 tccattggga taaattgcca gaagggtcta aaggtatcca agaagcattc gcacaagtag
    11161 gacaaggatt gtctcaaact cctgaaaaag ttactacttt ccaacaaaac ttggatatgt
    11221 tgattcctgg attatcagga ctactcctta ctttactttg catgtactta cttaagaaaa
    11281 aagtatctcc aatcactatt atccttgccc tcttcgcagt gggtattgtg gcacatgttc
    11341 ttcacatcat gtaatcaagc aactaaaaag gaaccaggtt ctaaaatctg attccttttt
    11401 tctatgcttt tattcagcca aggctcccat tggatcccat ggtgcaagta caattggttc
    11461 tgctccatag gcagcttgtt cttctgctgt cagcaattcc ttacgaacaa cgatttggta
    11521 tgtgtattcg tccatccaag cgtctgaggc aacaaagtaa ccatctgtac cgaccttgtc
    11581 tccccatgag ttttcaacct tccacttggt tgatttacca ttttcgtcca agtcaacacc
    11641 tgtcaagacc atggcgtggg tcatcaagct ttcgctatag tccaaacgtc cagccttgtc
    11701 ttgagtaagt ttaatgtcca tgcttgattc aaagtcataa acatctgtcg caaggatgcc
    11761 agccttacgg ttactgagct ggccgacatc agaaccaaac caaacagtct cacctgcttg
    11821 catttgggca atcgccaatt ctttcaagcg ctccattgga acgttgatgt aacgaactgc
    11881 acggctacca accacattcc ccaacatctc aactgtgtaa gattttccgt aaggtttatc
    11941 agcagttgga gcattgataa cagaaacgta gtcttctaaa ggaagattga catatttctt
    12001 gtaaaactct tgtggtgtga ttcctttttc acttttgtag ttgttatctt tatcgcgata
    12061 agcaaagtca aacttgcgtg gtggaagtcc taatgacata gcaagaaagt taaagatttc
    12121 ttgcaagagg tcttctttct tagcttgaac agtcgcttga tctgcaccag aaacaagcaa
    12181 gtcacgcaag atttgagcat cttgacgaag caatttatta aggatcgcat ttagctcacg
    12241 actgctgcta gatgaaacag actcaggata aactgactta ggcacgacac cgtatttttc
    12301 aaagagggaa acgaccatat cccattgacc accatcttgt tgaggtgttt ggagtaagaa
    12361 gctaaccttg cggctagtca attcttggtc tgaagtcgca atgacttgct ccaagaacca
    12421 gtttgatttc tcatacttat cccagaagaa agtgtgggct tgtgacaact caaagttctc
    12481 caatttgtat tgcgagatga gtttgtggcg gaaggtgttg agagccgcaa acatccagca
    12541 acgaccagac gctttctggt tagtgacctt gtccttggtt aaatccaatg agaaaacagg
    12601 tgtgttgtct acatggcttt ggcgacgttc cagagctgca aaaattccgt tgtggctagc
    12661 agcattttca atcgcttggt attttacatt tgcttcatag ttggcaaata gtttatcagt
    12721 aaatgattct tgaatcgcgt tcatagattc ctccttttat tctacagtct attataactc
    12781 ttttcacaaa ggaagcaact aaaaaacata aaaggtaagg acattctccc tcaccttttt
    12841 cgaatatata ctcttcgaaa atct
//
LOCUS       DAVHLA010000053        12770 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVHLA010000053 DAVHLA010000000
VERSION     DAVHLA010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12770)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12770)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12770
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.053"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            265..2556
                     /gene="pcrA"
                     /locus_tag="VVO77_001832"
     CDS             265..2556
                     /gene="pcrA"
                     /locus_tag="VVO77_001832"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEU5693800.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTTYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            2599..3279
                     /gene="radC"
                     /locus_tag="VVO77_001833"
     CDS             2599..3279
                     /gene="radC"
                     /locus_tag="VVO77_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEU5693801.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(3276..3965)
                     /locus_tag="VVO77_001834"
     CDS             complement(3276..3965)
                     /locus_tag="VVO77_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEU5693802.1"
                     /translation="MKKPVIGITGNEKAHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYNLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(3983..4624)
                     /locus_tag="VVO77_001835"
     CDS             complement(3983..4624)
                     /locus_tag="VVO77_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEU5693803.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(4707..4922)
                     /locus_tag="VVO77_001836"
     CDS             complement(4707..4922)
                     /locus_tag="VVO77_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEU5693804.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(4930..5277)
                     /locus_tag="VVO77_001837"
     CDS             complement(4930..5277)
                     /locus_tag="VVO77_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEU5693805.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFSLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(5282..6397)
                     /locus_tag="VVO77_001838"
     CDS             complement(5282..6397)
                     /locus_tag="VVO77_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU5693806.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(6407..7366)
                     /locus_tag="VVO77_001839"
     CDS             complement(6407..7366)
                     /locus_tag="VVO77_001839"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEU5693807.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(7479..8048)
                     /locus_tag="VVO77_001840"
     CDS             complement(7479..8048)
                     /locus_tag="VVO77_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEU5693808.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAEDYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            8176..8847
                     /locus_tag="VVO77_001841"
     CDS             8176..8847
                     /locus_tag="VVO77_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEU5693809.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            8831..9649
                     /locus_tag="VVO77_001842"
     CDS             8831..9649
                     /locus_tag="VVO77_001842"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEU5693810.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            9646..10542
                     /locus_tag="VVO77_001843"
     CDS             9646..10542
                     /locus_tag="VVO77_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU5693811.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            10586..11560
                     /gene="pta"
                     /locus_tag="VVO77_001844"
     CDS             10586..11560
                     /gene="pta"
                     /locus_tag="VVO77_001844"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEU5693812.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(11876..12770)
                     /locus_tag="VVO77_001845"
                     /pseudo
     CDS             complement(11876..12770)
                     /locus_tag="VVO77_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3716 a         2425 c         2755 g         3874 t
ORIGIN      
        1 aaatcatcgt aaacgcttcg gattacgaat gaatttgatt gctggcatta tcaatcatga
       61 actaggattc tagttttgca ggaagtctat tgaggtattg agctagttta tgaaaaaatt
      121 gggtgaaaaa gtcgagtgtt ttagaaaccc acagtgtagt attctagttt caatccacta
      181 tattttgcta ctccccgtaa agtttctatt ttccctgatt tctgatataa tagaaatatt
      241 gacttcaaga gtaaggaaga gaagatgaac gcattattaa atggaatgaa tgaccgtcag
      301 gctgaggcgg tgcaaacgac agaaggtccc ttgctaatca tggcaggagc tggttctgga
      361 aagactcgtg ttttaaccca ccgtatcgct tatttgattg atgaaaagct ggtcaatcct
      421 tggaatatct tggccattac ctttaccaac aaggctgcgc gtgagatgaa agagcgtgct
      481 tatagcctca atccagctac tcaggactgt ctgattgcga ccttccactc catgtgtgtg
      541 cgtattttgc gtcgcgatgc ggaccatatt ggctacaatc gtaattttac aattgtggat
      601 cctggtgaac agcgaacgct catgaaacgt attctcaaac agttgaactt ggatcctaaa
      661 aaatggaatg aacgaactat tttggggacc atttccaatg ctaagaatga tttgattgat
      721 gatgttgctt atgctgctca agctggcgat atgtatacgc aaattgtggc ccagtgttat
      781 acaacctatc aaaaagaact tcgtcagtct gaatccgttg actttgatga tttgattatg
      841 ctgaccttgc gtctctttga tcaaaatcct gatgttttga cctactacca gcaaaaattc
      901 caatacatcc acgttgatga gtaccaagat accaaccacg ctcagtacca attggtcaaa
      961 ctcttggctt cccgttttaa aaatatctgt gtggttgggg atgcggacca gtctatctac
     1021 ggttggcgtg gtgctgatat gcagaatatc ttggactttg aaaaggatta ccccaaagct
     1081 aaggttgttt tgttggagga aaattaccgc tcaaccaaaa ccattctcca agcggccaac
     1141 gaggttatta aaaataataa aaatcgccgt cctaaaaatc tctggactca aaacgctgat
     1201 ggggagcaaa tcgtttacta tcgtgctgat gatgagctgg atgaggctgt atttgtagcc
     1261 agaaccatcg atgaacttag tcgcagtcaa aacttccttc ataaggattt tgcagttctc
     1321 tatcggacta atgcccagtc ccgtacaatt gaggaagccc tgctcaagtc taacattcct
     1381 tataccatgg ttggcggaac caaattctac agccgtaagg aaattcgcga tattattgct
     1441 tatctcaacc ttattgctaa tttgagtgac aacattagtt ttgagcgtat tatcaacgag
     1501 cctaaacgtg gaattggtct aggtacagtt gagaaaatcc gtgattttgc aaatttgcaa
     1561 aatatgtcta tgctggatgc ttctgctaat attatgttgt ctggtatcaa gggtaaggca
     1621 gcccaatcta tctgggattt tgccaatatg atgcttgatt tgcgggagca gctagaccac
     1681 ttaagcatta cagagttggt tgagtccgtc ctagaaaaaa caggttatgt cgatattctt
     1741 aacgcccaag cgactctaga aagcaaggca agggttgaaa atatcgaaga gtttctttct
     1801 gttacgaaga actttgatga caccactgat gtgacagaag aggaaactgg tctggacaaa
     1861 ctgagtcgtt tcttaaatga cttggctttg attgccgaca cagattcagg tagtcaggag
     1921 acatcagaag tgaccttgat gaccctgcat gctgccaaag gtctcgaatt tccagttgtc
     1981 tttttgattg ggatggaaga aaatgtcttt ccacttagtc gtgcgactga agatccagat
     2041 gaattagaag aagagcgccg tctagcctat gtaggtatca cgcgtgcaga gaaaattctc
     2101 tatctgacca atgccaactc acgcttgctt tttggtcgta ccaattataa ccgtccgact
     2161 cgttttatta acgaaatcag ttcagacttg cttgagtatc aaggtctggc tcgtcctgca
     2221 aatacaagct ttaaggcatc atatagcagt ggtagtattt cctttggtca aggtatgagt
     2281 ttggctcagg ctcttcaaga ccgtaaacgc ggtgctgccc caaaatcgat ccagtcaagc
     2341 ggtcttccat ttggtcaatt tacagctggc gcaaaatcag catctagcga ggcaaattgg
     2401 tccattggtg acattgctct ccacaagaaa tggggagagg gaactgttct ggaagtttca
     2461 ggtagcggtg ctaggcagga attgaaaatc aatttcccag aagtaggttt gaaaaaactt
     2521 ttagccagtg tggctccaat tgagaaaaaa atctaatttt ccatccttct cacgaataat
     2581 aaagtgagga ggatttttat gtacagtatt tcattccaag aagattcact attaccaaga
     2641 gaaaggctgg ccaaggaagg agttgaagcg cttagtaacc aagagttgct agctatttta
     2701 ctcaggacag gaacacgtca agctagcgtt tttgaaattg cccaaaaagt cttgaacaat
     2761 ctttcaagcc taacggattt gaaaaaaatg accctgcagg aattgcagag tttgtctggt
     2821 attgggcgtg ttaaggccat agaattacaa gctatgattg aactggggca tcgtattcac
     2881 aaacacgaga ctcttgaaat ggaaagtatt ctcagcagtc aaaagttggc caagaagatg
     2941 cagcaggaat taggggataa aaaacaagag cacctggtgg cactctatct caatactcaa
     3001 aatcaaatca tccatcagca gaccattttt atcggttctg taactcgtag tatcgctgaa
     3061 ccgcgagaga ttcttcacta tgcaatcaag catatggcga cttctcttat cttggtccac
     3121 aatcatcctt caggagcggt agcgcctagc caaaatgatg atcatgtcac taaacttgtt
     3181 aaagaagcct gcgaattgat ggggattgtt ctcttggacc atttgattgt ctctcattct
     3241 aattacttta gttatcgtga aaagacagat ttaatctaaa gttcattaac gacatagtca
     3301 aagagttttt tatctttggg acgattttca aaaagaagtt ctggatgcca ttggacaccg
     3361 agaaaggcga catcatccgt actcatgaca gcctcaatga taccatcttt aggatcatga
     3421 gccacaactt ttaaatttgg tgctaagtcc ttgatgctct ggtggtggaa ggagttgata
     3481 tgagagattt ctccatagat ttcttggaga acggtatctg gttctgttac caagcgttga
     3541 gttgtgtact caacagaaga atcctgccaa tggtcttcga tatcttggta caaagttcca
     3601 cccatggcaa cgttaaagag ttgggtacca cggcagacag agaaaatggg ctttttctgt
     3661 ttaatagctt ccttgatgag ggccagttcg aagatatctc tttgaaggtt atagtcatcg
     3721 ctatcaatgg ttttgggttc gccataaaat tttggatcga cattttgccc acctgtcaag
     3781 atgagcttgt caatcaaact gatatagtgg caggccattt cttgatcacc aatcggtagg
     3841 atgatgggaa tccctccagc atctttaacg ccttcaacaa agccttttgc tgcgtagctc
     3901 atcatgatgt catcatctgg atgagctttt tcgtttcctg taatcccaat aactggtttt
     3961 ttcataaaat gattttcgct ttctaatcct cttttcgcat gaagtagagg agggtttgga
     4021 gttcacttgt caaatcgaca tactgaacga ccacgtcttt tggtaaatgc agatggactg
     4081 gtgaaaaact gagaattcct ttcacaccag catcaaccaa gagattagca acctcttgtg
     4141 acttgacgct gggaacagtt aggatagcag tcttcacatc agcatccttg attttatcct
     4201 tgatctgaga aatcccgtaa atgggaatcc cgtcaggagt ttgggtaccg acttcaggat
     4261 ggtcgtctag gtcaaaggcc atgataatct tcatcttgtt acgttcgtgg aagcggtagt
     4321 ggagaagggc atggcccata tttccaatac caaccagcat gacattggta atagagttgt
     4381 cattgagcaa atcggcaaaa aatgtcatta gttttttgac atcatagcca aaaccacgac
     4441 gaccaagttc accaaaatag gaaaaatcac gacgtacggt cgctgaatca ataccgatag
     4501 cctctgcaat ttgcttagag ttggcacgtt caatcttttc tgcatgaaat ctcttaaaaa
     4561 ttcgatagta gagagagagt ctttttgctg tagcttttgg aatagcaaac tgtttatctt
     4621 tcacaaaatc acaacctttc tattcttcta ttttatagaa acattgtgaa aaaatcaaca
     4681 aaaataagaa aaaactaaga aaaatcttag ttttgatgta aaaaatctgc atgagataga
     4741 aaacggtaga ggtctccgac cagaccctga taaacttttt ggcccctaaa agtcagagaa
     4801 gtcacataaa gtgtatctgg taaggttaca catcctgaca aagtcaacat gagagcctca
     4861 tgatcctcat acttgagagt acgctctaca tgatagcagt ccttataggt cagttcaaac
     4921 attttggctc tatctttccg attttgtaaa gacaccacgt tctaccaagc tatccatgag
     4981 gaagtagaat ttttcctgat gaatatggtg gtcttctgat ttgaaaatat caactagacg
     5041 aaggctaaac ttgtcagtga tattgatttt agcccctgta agttccttgt taatgatgat
     5101 tttgagttgg aagccttcac cgctgtttgg cactttttcc aaaaggcgag tcagttcata
     5161 gttaccaacc ttagtttcaa aaaaggtgtt atctttgagg gtgaattttt taacagaagg
     5221 gctaagagtg taatcgtaac gacaattttt taactgaatg attttttcaa atgccatatg
     5281 gctaacctcc gataatttct tttaaggttt ttgcgagggt ttgtaggtct tcaacggtat
     5341 tttgtggcga caaactgatg cgaagggatt ccttcaagcg ttctgaattt gcgccataca
     5401 tggcttcaag aacatggctg gattggacaa cgcctgcagt acaggctgag ccagtagaga
     5461 ttgaaattcc agctaaatct agccgaagga gtaagaggtc atttttctga ccaggaaatc
     5521 caatattgag aacataaggg agatgatgtt ttcctctatt caggtaatac tgaatgccct
     5581 ccagctctgc cagaaaggcg gtttctagat tttgtacatg ttgaaaatgt tcttcttgtt
     5641 tttctaggtc ttcttttagg gctgcaacca tgcctacgat agcaggcaga ttttcagttc
     5701 ctgcacgttt tttctgttcc tggtctccgc catgtagata ggaatcaaag tccatgctag
     5761 atgcgtagag aaaaccgatt cccttaggac catggaattt gtgggcagaa gcagtgagaa
     5821 aatcaatgcc caattcttct gaatgaattg ggattttacc aatagcctga actgcatcaa
     5881 catgataggc agcagggtgt tgcttgagta tttggccaat ttcagcgatg ggcagtaggt
     5941 ttcctgtctc attattggca aacatggtag aaaccaaaat cgtatcgtca cgtaaagcct
     6001 tttgaatttg ctgggctgtg atttcttgat tttctggctg gataatggtt gcttcaaacc
     6061 caaagtgttg aaccaagtaa tcaattgttt caaggacagc atggtgctcg atggcagttg
     6121 tgatgatatg ttttccttgt tcttggtgac gaagacagta gccaatgatg gtagtattat
     6181 tgccttcagt cccaccagaa gtgaaaaaga tatgttgagg ttttgtcctt agtaactggg
     6241 ctagttcctg acgggcttct cgcaagagtt tgccagcttg acgaccatga ccatgaatac
     6301 tagaaggatt tccgtgggtt tcttgcataa ccttggtcat agctgaaata gcaactgctg
     6361 acataggagt cgttgcagca ttgtccaaat aaatcaaaga atcaccttat ttctttttat
     6421 tgtaggcaaa gagtgggctg actggttttc tttcgtgaat acggacgata gcatcaccaa
     6481 ttaactcact agcagtgatg tagcatacat ttttaggagt tttttctttt gttgctactg
     6541 aatcagtcac aagaatttct ttaatattag tattgtcaag aagctcagca gctccctcga
     6601 cgaagagacc gtggctagaa acagcataaa tttctgtagc tccttcacgt tcaacgattt
     6661 tagaagcttc agagaaggta cgtcctgtat ttaaaatatc atcaatcaag atagctttct
     6721 taccttcaac atcaccaata atataacctt cgttacgagt tgcatcgtct tgagggtagt
     6781 cgataatggc gataggagca tcaagatatt cagccaggct acgcgcacgt ttgacacctg
     6841 aatttttagg gctaacgaca acaacatctg aaccaagcaa tcctttatcg cagtaatgtt
     6901 ttgcgaatag gggaacagtg aaaagattat ccactggaat atcaaagaaa ccttgaacct
     6961 gaacggcatg caaatcaaga gtcaggatac gatcaactcc agccttaacc agcatattgg
     7021 caactagttt tgctgtaagt ggctcacgag gacaagcaat gcggtcttga cgtgcatagc
     7081 caaaatatgg aaggacaacg ttgatactgt gggcacttgc acgcacacaa gcatcgacca
     7141 tgattaacaa ttccattagg tggttgttga cagggaaact tgttgattgg atgatgtaaa
     7201 catcataacc acggacactt tcttcgatat ttacttggat ttctccgtct gaaaattgac
     7261 gtgatgatag ttttccaagt gggacaccaa cagcttgggc aattttttgt gcaatctctt
     7321 ggttagagtt gagtgcgaaa agtttcatgt tttttctatc tgacattata gaccgtcctc
     7381 tgtaaacttt ataaatccta gttatattta ccttacatat atgaactggg atttgtgtat
     7441 ttttatcttt tctattttac caaaaaatgg agattatttc agctattttt catacttttg
     7501 acaaatcgaa ccaattttga aggagctttt tggtaggaaa tctgattttt ctctaaaaat
     7561 tgtcggaaat cctgtttgcc ttgctcatga ttttccactt caagctccaa ttcgtaatct
     7621 gttatatcaa agtatcggct ctgatccagt gccatgagac caatagctgt tttcatttca
     7681 tagcgaagcg ttgttagaca accaagaacc tgccagttct tactttggat accatgtttc
     7741 gccaattcat ccagtactag tccttgagga agttcttcct tactcagata gtcctcagca
     7801 tcttttagtt gcaatttttg gttgtattcc atgtttccaa cactctgcgg gactttgagt
     7861 gtcaactcag cccagtcttc aaaggttcga atgcgcatag cgactttctt ttctcgcagt
     7921 tcaaaatcag gcgtgtcgat gtagtaattt gtttgaagaa caggagtgac acctgtgaac
     7981 tggtctttta gacgattgta ttcatctttt ttcaatagtg ttttcaattc aatttctaaa
     8041 tgtttcattt ttcttacctt tttttatcgt tgaaagcgga tttatggtat aataagcatt
     8101 gtatttattg tatatgaatc tggagaaaaa atcaaagata tttttgacgg ataatatgag
     8161 aacaagggag aatatatgac cttagaatgg gaagaatttc tagatcctta cattcaagct
     8221 gttggtgagt taaagattaa acttcgtggt attcgtaagc aatatcgtaa gcaaaataag
     8281 cattctccaa ttgagtttgt gaccggtcga gtcaagccaa ttgagagcat caaagaaaaa
     8341 atggctcgtc gtggcattac ttatgcgacc ttggaacacg atttgcagga tattgctggc
     8401 ttacgtgtga tggttcagtt tgtagatgac gtcaaggaag tagtggatat tttgcacaag
     8461 cgtcaggata tgcgaatcat acaggagcga gattacatta ctcatagaaa agcatcaggc
     8521 tatcgttcct atcatgtggt agtagaatat acggttgata ccatcaatgg agctaagact
     8581 attttggcag aaattcaaat tcgtactttg gccatgaatt tctgggcaac gatagaacat
     8641 tctctcaact acaagtacca aggggatttc ccagatgaga ttaagaagcg actggaaatt
     8701 acagctagaa tcgcccatca gttggatgaa gaaatgggtg aaattcgtga tgatatccaa
     8761 gaagcccagg cactttttga tcctttgagt agaaaattaa atgacggtgt aggaaacagt
     8821 gacgatacag atgaagaata caggtaaacg aattgatctg atagccaata gaaaaccgca
     8881 gagtcaaagg gttttgtatg aattgcgaga tcgtttgaag agaaatcagt ttatactcaa
     8941 tgataccaat ccggatattg tcatttccat tggcggggat ggtatgctct tgtcggcctt
     9001 tcataagtac gaaaatcagc ttgacaaggt ccgctttatc ggtcttcata ctggacattt
     9061 gggcttctat acagattatc gtgattttga gttggacaag ctagtgacta atttgcagct
     9121 agatactggg gcaagggttt cttaccctgt tctgaatgtg aaggtctttc ttgaaaatgg
     9181 tgaagttaag attttcagag cactcaacga agccagcatc cgcaggtctg atcgaaccat
     9241 ggtggcagat attgtaataa atggtgttcc ctttgaacgt tttcgtggag acgggctaac
     9301 agtttcgaca ccgactggta gtactgccta taacaagtct cttggcggtg ctgttttaca
     9361 ccctaccatt gaagctttgc aattaacgga aattgccagc cttaataatc gtgtttatcg
     9421 aacactgggc tcttccatta ttgtgcctaa gaaggataag attgaactta ttccaacaag
     9481 aaacgattat catactattt cggttgacaa tagcgtttat tctttccgta atattgagcg
     9541 tattgagtat caaatcgacc atcataagat tcactttgtc gcgactccta gccataccag
     9601 tttctggaac cgtgttaagg atgcctttat cggtgaggtg gatgaatgag gtttgaattt
     9661 atcgcagatg aacatgtcaa ggttaagacc tttttaaaaa agcacgaggt ttctaaggga
     9721 ttgctggcta agattaagtt tcgaggtgga gctattctgg tcaataatca accgcaaaat
     9781 gcaacgtatc tattggacgt tggagactac gttaccattg acattcccgc tgaggaaggc
     9841 tttgaaacct tggaggctat tgagcatcca ttagatattc tctatgagga tgaccacttt
     9901 ctagtcttga ataaacccta tggagtggct tctattccta gtgtcaatca ctctaacacc
     9961 attgccaatt ttatcaaggg ttactatgtc aagcaaaatt atgaaaatca gcaggttcac
    10021 attgttacca gactagatag ggacacttct ggcttgatgc tctttgccaa gcacggttat
    10081 gcccatgcac gattagacaa gcagttgcag aagaaatcta tcgagaaacg ctactttgct
    10141 ttggttaagg gagatggaca tttggagcca gaaggggaaa ttattgctcc gattgcgcgt
    10201 gatgaagatt ccattattac cagacgagtg gctaaaggcg gaaagtatgc ccatacttca
    10261 tacaagattg tagcttctta tggaaatatt cacttggtct atattcacct gcacactggt
    10321 cgaacccatc aaatccgagt ccatttttct catatcggtt ttcctttgct gggagatgat
    10381 ttgtatggtg gtagtctgga agatggtatt caacgtcagg ctctgcattg ccattaccta
    10441 tccttttatc atccattttt agagcaagac ttgcagttag aaagtccctt gccggatgat
    10501 ttcagtaacc ttattaccca gttatcaact aatactctat aaaaactgtc tcagagtata
    10561 attattatct taaaggagaa aactcatgga agtttttgaa agtctcaaag ccaaccttgt
    10621 tggtaaaaat gctcgtatcg ttctccctga aggggaagag cctcgtattc ttcaagcaac
    10681 aaaacgctta gtaaaagaaa cagaagtgat tcctgttttg cttggaaatc ctgaaaaaat
    10741 taaaatttat cttgaaattg aaggaatcat ggatggttat gaggtcatcg accctcaaca
    10801 ttatcctcaa tttgaagaaa tggtttctgc cttggtggag cgtcgcaagg gcaaaatgac
    10861 tgaagaagat gtacgcaagg ttttggttga agatgtcaac tactttggtg tgatgttggt
    10921 ttacttgggc ttggttgatg gaatggtgtc aggagcgatt cactcaacag cttcaacagt
    10981 tcgtccagct ctacaaatca tcaaaactcg tccaaatgta actcgtactt caggagcctt
    11041 cctcatggtt cgtggtacgg aacgttacct atttggagac tgtgccatta acatcaatcc
    11101 agatgcagaa gccttggctg aaattgccat caactcagca atcacagcta agatgtttgg
    11161 catcgaacct aaaattgcca tgttgagcta ttctactaaa ggttcagggt ttggtgaaag
    11221 cgttgataag gtcgttgaag caactaaaat tgctcacgac ttgcgtcctg accttgaaat
    11281 cgatggtgag ttgcaatttg atgcagcctt tgttcctgaa actgcagctc tgaaagctcc
    11341 tggaagtacg gtagctggtc aagcaaatgt cttcatcttc ccaggtatcg aggccggaaa
    11401 tatcggttac aagatggctg aacgcctggg tggctttgcg gctgtaggac ctgttttgca
    11461 aggtttaaac aagccagtta atgatctttc tcgtggatgt aatgcagatg atgtttacaa
    11521 gttgaccctc atcacagcag ctcaagcagt tcatcaatag tgaaaactat aaagcgatat
    11581 actatgctat actgtagtta tgaaactatg tacgaaaagc actgccatta attcctgaga
    11641 actaaattac tgattggtgt caaaaaggaa aacttccaag cgatgatatc ctgtctatac
    11701 acgacctata gaaatctgta atatgtatgt ccgtaaaacg ataatttccc tttttgattt
    11761 taaatgagta tgaaaagaga attttttcat gagaaaacgc ataatattaa gtgtcttgac
    11821 acctgctatt atgcgttttc tggctctttg tcaactgtag tgggttgaag aaaagctaag
    11881 ctcgagaaag gacaaatttt gtcctttctt ttttgatatt cagagcggta aaaatccgtt
    11941 ttttgaagtt ttcaaagttc cgaaaaccaa aggcattgcg cttgataagt ttgatgagat
    12001 tattggtcgc ttccaatttg gcgtttgaat agggtagttg aagggcgttg acgattttct
    12061 ctttgtcctt tagaaaggtt ttaaagacag tctgaaaaag aggatgaacc tgctttagat
    12121 tgtcctcaat gagtccgaaa aatttctccg gttccttatt ctgaaagtga aacagcaaga
    12181 gttgatagag ctgatagtga tgtttcaagt cttgtgaata gctcaaaagc ttgtctaaaa
    12241 tctctttatt ggttaaatgc atacgaaaag taggacgata aaatcgctta tcactcagtt
    12301 tacggctatc ctgttgaatg agtttccagt agcgcttgat agccttgtat tcatgggatt
    12361 tcggatgatg gcttgtgttc tgctctcaag aacagttatg atattgagct tatcaaagtc
    12421 ctgagcaata aagctcatct ccatctcccg attgaaacag tcactccccg gactgtttca
    12481 acgtcccaag acataatctc aggaagacgc gaaaaatcat gctcaaagtg aaaatcattg
    12541 agcttacgaa taacagttga agttgagatg gaaagctgat gggcaatatc agtcatagaa
    12601 atcttttcaa ttaacttttg agcaatcttt tggttgatga tacgagggat ttggtgattc
    12661 ttcttgacga tagaagtttc agcgaccatc atttttgaac agtgatagca cttgaatcga
    12721 cgctttctaa ggaggattct agtaggcata ccagttgtct caaggtaagg
//
LOCUS       DAVHLA010000054        12720 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVHLA010000054 DAVHLA010000000
VERSION     DAVHLA010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12720
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.054"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            1..521
                     /locus_tag="VVO77_001846"
                     /pseudo
     CDS             1..521
                     /locus_tag="VVO77_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            complement(723..2981)
                     /locus_tag="VVO77_001847"
     CDS             complement(723..2981)
                     /locus_tag="VVO77_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU5693813.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(3210..3440)
                     /locus_tag="VVO77_001848"
     CDS             complement(3210..3440)
                     /locus_tag="VVO77_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEU5693814.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3630..4313
                     /locus_tag="VVO77_001849"
     CDS             3630..4313
                     /locus_tag="VVO77_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU5693815.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            4313..5047
                     /locus_tag="VVO77_001850"
     CDS             4313..5047
                     /locus_tag="VVO77_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU5693816.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKLIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            5201..6058
                     /locus_tag="VVO77_001851"
     CDS             5201..6058
                     /locus_tag="VVO77_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEU5693817.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETGLVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAMDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLAHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            6200..7072
                     /locus_tag="VVO77_001852"
     CDS             6200..7072
                     /locus_tag="VVO77_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEU5693818.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            7354..8037
                     /gene="rpiA"
                     /locus_tag="VVO77_001853"
     CDS             7354..8037
                     /gene="rpiA"
                     /locus_tag="VVO77_001853"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEU5693819.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            8051..9262
                     /locus_tag="VVO77_001854"
     CDS             8051..9262
                     /locus_tag="VVO77_001854"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEU5693820.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            9264..9806
                     /locus_tag="VVO77_001855"
     CDS             9264..9806
                     /locus_tag="VVO77_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HEU5693821.1"
                     /translation="MTRYSLLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGN
                     IFFTSIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYHKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            9822..10631
                     /locus_tag="VVO77_001856"
     CDS             9822..10631
                     /locus_tag="VVO77_001856"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEU5693822.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGGFKGLLKAILAEL"
     gene            11107..11502
                     /locus_tag="VVO77_001857"
     CDS             11107..11502
                     /locus_tag="VVO77_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HEU5693823.1"
                     /translation="MLDSKEELKESENDAPKLETPLREEPRLAPQTLPEASEVLENKR
                     EESKVEITEPAQADDIRKVVGELAKDISITKLYMTGHSLGGYLAQIAAVEDYQKYPDF
                     YNHVLRKVTTFSAPKVITSRTVWDAKNGF"
     gene            11512..12087
                     /locus_tag="VVO77_001858"
     CDS             11512..12087
                     /locus_tag="VVO77_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000445853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEU5693824.1"
                     /translation="MESRKLAVSGKIKHYVVDNDNVVTPLIHNNRDIVTFTGNSRFKH
                     RSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKVRFFKKQALPQSSSQPSAEPME
                     NIALGKQVTQSSTAFGGDARRAVDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIR
                     QINIYNRTDTAQDRLANFDVILLDSSGKEIE"
     gene            12159..12623
                     /locus_tag="VVO77_001859"
     CDS             12159..12623
                     /locus_tag="VVO77_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEU5693825.1"
                     /translation="MELEGYNALSLAEVEVFRFIATNAETATQVSKPVQPISQTPVKD
                     KTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGCNQTAGFVLNLPIKENM
                     RNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTLNSKVSDDDVL"
BASE COUNT         3770 a         2320 c         2866 g         3764 t
ORIGIN      
        1 tatttcttaa gaattttaat agattaaagc acctagcacc tgtttagatt gacgaaacag
       61 gattcgatac ttatttttat cgagaatatg gtcgctcatt aaaaggtcag ttaataagag
      121 gtaaagtatc tggaagaaga tatcagagga tttctttggt tgcaggtcta acaaatggtg
      181 agttaatcgc tccaatgact tacgaagaga tgatgacgag cgactttttt gaagcttggt
      241 ttcagaagtt tttcttacca acattaacca caccatcggt tattattatg gataatgtaa
      301 gattccatag aatggggaag aatgtaagat tccatagaat ggggaagcta gaacttttat
      361 gcgaagagtt tgggcataaa cttttacctc ttcctcccta ctcgcctgag tacaatccta
      421 ttgagaaaac atgggctcat atcaaaaagc acctcaaaaa ggtattacca agttgcaata
      481 ccttttacga ggctcttttg tcctgttctt gtttcaattg actatagcag attgaaatga
      541 gaacaaatcg attgggaaag taaaattaat ttctataaat gttttagcaa ttgtttcgta
      601 ctatttcaga ttcagtctac tatatatcat aatggacaaa gggcaagctg tcaagaaatt
      661 acagttattt tagtaaaaaa agaagcagaa aaatttcatt ttctactcct tttctatagg
      721 atttattttt ctttttcaga acttttaact tcagcttttt tggcagattt aatctgaatg
      781 tttcccttgc tagtcataac tgctttgaga tctttttcgc ttggattttc aaggtagtag
      841 tcagtgattg tgtcctcaat atagtcttga atagtccgac gaagtgggcg tgctcccatt
      901 tttggatcat aacctaggtc aaccaacttt tccttgacct tatcagttac atccaaacga
      961 atgttgttgc tagagaggcg cttgttaaca tctgctagca tgagctcgac aatctgaagg
     1021 aggttatcct tgctgagagc cttaaattcg ataatgccat caaaacggtt cataaactct
     1081 gggctaaaga agttaccgag ttcaccgagg acagaattgg tacgtccttc tctagcagca
     1141 ccaaatccaa cgctagcttc ggtctttcct gtacctgcat ttgaggtcat gataatgatg
     1201 gcatccttga agctaacggt gcgtccttgc ccgtctgtca aacgaccatc gtccaagact
     1261 tgaagaaaca tgtgcataac atctgggtga gctttttcca cttcatcgag aaggatgaga
     1321 gaatatggat tgtggcgaac tttttcagtt aattgaccag cctcatcata gccaacataa
     1381 cctggagggg cgccgaccaa cttagccaca ctatgttttt ccatgtattc actcatatca
     1441 aagcgaatca tactatcagc agaaccaaaa agttcgatag ccagttgttt ggaaagttct
     1501 gtcttaccga caccagttgg cccaacgaag aggaagcttc cgattgggcg gttaggggta
     1561 ccaagtccga cacgattacg gcgaatagcc ttggcaatct tatcgactgc atcatcttgg
     1621 ccaataacat gagacttgag atcttcggct agatggatga gttgagattg ttctttctct
     1681 ttcaaatcac caacagggat attggttttc tgctcgataa tgtgctcaat agttttctcg
     1741 ctgatgatag gagtatcctg gtctgtgatc tttttctttt gcatttcctt atacttggca
     1801 atctggtcgc ggaagtaggc cgccttctca aaatcttctt ctcgtgtagc ttgagacttg
     1861 agattttcag cctcaatcaa gcgctgatca attactttag gatccacaaa attcaaggtc
     1921 aagttcatct tagaaccagc ttcatctagg aggtcaatgg ccttgtcagg caagaagcga
     1981 tcttggatgt agcgattgga aagagttgca gctgcttcaa tcgcagcatc ggtatattga
     2041 acgtggtggt aatcttcgta tttcttttga atccctttga gaatagtgat tgtttcgtcc
     2101 accgttggtt catcgacttt aacaggctgc atacgacgct cgagggcagc atccttttca
     2161 atgatacggt attcattgag ggtagtagca ccgactagtt gcagttctcc acgagcaagg
     2221 gctggcttga ggatatttcc tgcgtccata ttaccatcac tcgcagaacc agcaccaaca
     2281 atttcatgga tttcatcgat aaagaggatg atgtcttcac gtttgcgaat ttcttccatg
     2341 agtttttgca tgcgttcttc aaattgtcct cgaatccccg ttccttgaac taagctaacc
     2401 acatccagac ggatgacttg tttaccttgg agtttatgtg gcacatcgcc atcgacaatt
     2461 ttctgagcta gaccttcgac aacggccgtt tttccgacac caggttcacc gataaggaca
     2521 ggattattct tggttctacg attgagaatc tcgatgacac ggataatctc atcgtcgcgc
     2581 ccaataacgg ggtcaatgtc tccacgacgg gcaatttcag ttacattaat accaaattct
     2641 tccagcaggc ctttttcttg gctaggtggc ggagtttgag cagatccacg attttgggaa
     2701 ccataaccgc cgtttccacc gtaacctcca cctgattggg ttgggggaat aggaggagta
     2761 ttgctagaag gtctgaaatt gtttagatca ttgaagaaat caccaaaggg atcgaagtca
     2821 cgattgttca gatccgtcat acctttgaag aggctattgt taggatctgt tttgataatc
     2881 ttatagcagt tttgacagag gtcaatttgt ttttgttttc cattgagatt ggtgtaaaga
     2941 tgaattgttg agtcgttaat tttacagttt tgacaaagca tacatctacc tcatttcttt
     3001 ctttagcctg acttgtttaa aggtcaaaaa tagtcaaatt ctatactctc attataacag
     3061 gattggggtg taaagcaagt aaaaagattg aagctttgag aagttgttac aatgaaaatt
     3121 tttgtgaatt tggactataa aaaaatccta tttgtgagac aaaaaggatt ttacttagac
     3181 atgcagggac aatcccagct tgttttagat tagtagagaa gttcgtaaat ttccattgcg
     3241 attaagtcaa tgctatcaaa cgtatacgtt tcgcgatctt ctacgtcacg aagggtaaag
     3301 attgggccgt tttcttcgtc gtggctgtac gcaacttctg caacaacaac tccttcgcgt
     3361 tcaaaattac gttttaaatt tccgccatcg tttgccattg cttcaaggcg gttgatgatt
     3421 ctaaccaaat gtgattccat tttgattctc cttcatttct tatcgttact attttaccat
     3481 aaaggaggcc aacttgacta gaaaaaacta agatttctca ctaattctgc tagtttaaag
     3541 atttttaaat aaattggata aaagatttaa attttaattc aaaacatgtt ataatcatac
     3601 agtattctat tttagaaagc agtgtgacta tgaatttttc ttttttacct aagtatttac
     3661 cttattttaa ctatggggct gttgtgacga ttcttatttc tatctgtgtt atctttttgg
     3721 gaactatttt gggtgttgtc ttggcttttg ggcaacgttc aaagtttaaa ccgcttgttt
     3781 ggttggccaa cttgtacgtt tggattttcc gtgggacacc gatgatggtt caaattatga
     3841 ttgcctttgc tcttatgcat atcaatgctc cgactattca gattggaatt ttaggtgttg
     3901 atttttcgcg tctgattcca gggattttga ttatctctat gaatagtggt gcttatgttt
     3961 cggagactgt tcgtgccgga atcaatgcgg ttccaaaagg tcagctagag gcggcttatt
     4021 cgctagggat tcgtcctaaa aatgcgatgc gttatgtgat tttgccacaa gcagtcaaaa
     4081 atatcttgcc agcattgggg aacgaattta tcaccattat caaggacagc tccctcttat
     4141 cagctattgg ggtcatggag ttgtggaatg gggctacaac agtttctaca acaacctatc
     4201 tacctttaac accactttta tttgcagcat tttactactt gattatgacc tctattctga
     4261 cagtagcctt gaaagctttt gaaaaacata tgggacaagg agataagaaa taatgacaga
     4321 aaccttgata aaaattgaaa atttacataa atcttttgga aagaatgaag tattgaaggg
     4381 catcaacctc gagattaaaa gaggagaagt tgtcgttatc atcggtcctt cagggagtgg
     4441 gaaatctacc ttgcttcgct ctatgaattt gttggaggaa gcaaccaagg ggaagcttat
     4501 ctttgaggga gtcgatatta cggacaagaa gaatgacctg tttgccatgc gtgagaagat
     4561 gggcatggtt ttccaacaat ttaacctctt tcctaatatg actgtgatgg aaaatattac
     4621 cttgtcacct atcaagacta aaggtgaaag cagggaagtt gctgagaaga gagcccaaga
     4681 gcttttggaa aaagttggtt tgccagataa ggcagacgct tatccacaga gtctgtcggg
     4741 tgggcaacaa caacggattg ccatcgcgcg tgggttggct atggaaccag atgttttgct
     4801 ctttgacgaa ccaacttcag ccttggatcc tgaaatggta ggtgaggtat tggctgttat
     4861 gcaagacctt gccaagtcag ggatgactat ggttatcgta acacatgaga tgggatttgc
     4921 ccgtgaggtg gcagatcgtg ttatctttat ggcagacggt gtggttgttg aagatgggac
     4981 acctgagcag atttttgaac aaacccaaga acaacggact aaagatttct tgagtaaggt
     5041 tttataatct attttaaaat ttcaagacaa gattagtgaa aagttcaacc agagcttttt
     5101 cttatagttt gaaactatag gataacctag gaaagaagtg ttagagggca ctagcagttt
     5161 ttggtataat ggaagatatt tgaaagaaaa gagaagtgat atgacacaga ttattgatgg
     5221 gaaagcttta gcggccaaat tgcaggggca gttggctgaa aagactgcaa aattaaagga
     5281 agaaacaggt ctagtgcctg gtttggtagt gattttggtt ggggataatc cagccagcca
     5341 agtctacgtt cgcaacaagg agaggtcagc tcttgcggct ggttcccgta gcgaagtagt
     5401 gcgagttcca gagaccatta ctcaagagga attgttagac ctgattgcta aatataatca
     5461 ggatccagct tggcatggga ttttggtcca gttgccatta ccaaaacata tcgatgaaga
     5521 ggcggtttta ttagccatgg atccagaaaa ggatgtggat ggtttccatc ccctaaacat
     5581 gggacgtctt tggtctggac atccagtcat gattccctcg acacctgcag gaattatgga
     5641 aatgtttcat gaatatggga ttgacttgga aggtaaaaat gcggtcgtca tcggtcgttc
     5701 aaatatcgtt ggaaaaccta tggctcagct tcttttggct aaaaatgcga cagtaacctt
     5761 ggcccactca cgaactcata atcttgccaa ggtggctgct aaagcagata ttcttgtagt
     5821 cgcaatcggc cgcgccaagt ttgtgactgc tgactttgtc aaaccaggtg cggttgtcat
     5881 tgacgttggg atgaatcgag atgaaaatgg gaagctctgt ggagatgttg attatgaggc
     5941 agttgcacca cttgctagcc atatcacgcc agtccctgga ggtgtcggtc ctatgaccat
     6001 taccatgctg atggagcaaa cttatcaagc agcacttcgg acattggata gaaaataaga
     6061 gaaacattcg attaatagag tgtattttct atagctatat ctaaaatggc agaaatgaat
     6121 attaaatttt agatataaga ttacaaaagg aggtctgcgt ctccttttta ttgtataata
     6181 aaagtgagag gaaaaaagga tgaaagtgat taatcaaacc ttattagaaa aagttattat
     6241 tgaacgttct cgttcaagtc ataaaggaga ttatggtcgt ctgctgctgc ttggtggtac
     6301 ttatccttat ggaggtgcca tcatcatggc tgctttagca gctgtaaaaa gcggtgcagg
     6361 attggtgacc gttggaacgg acagggaaaa tatcccggct ctgcacagcc atttacctga
     6421 gcctatggcc ttttctcttc aagaccagca attgttaaaa gagcaattgg agaaggcaga
     6481 agttgtcttg ctggggcctg gtttacgaga cgatgcttct ggagaaaatc tagtaaaaca
     6541 ggtctttgtt aatttaagcc aaaatcagat tttgattgta gacggaggtg ccttgaccat
     6601 tcttgctagg acaagtttgt catttccctc aagccagctt atcctaactc ctcaccaaaa
     6661 agaatgggaa aaattatctg gaattacgat tgaaaagcaa aaggaagatg caacggctag
     6721 tgttctgact tccttccctc aaggaacaat tttggtggag aaaggcccag ctactcgtat
     6781 ttgggaagtt ggccaatctg attattacca gttacaggtt ggtggtcctt atcaggcgac
     6841 tgggggaatg ggagatactc tggctgggat gatcgcagga tttgtaggcc aattccgaca
     6901 agccagtctc tacgagcgtg tggcagtagc gacccatctt cattcagcca tagcccaaga
     6961 actatctcaa gaaaattatg tggtcttacc gacggaaatc agcaggtatc ttcccaaaat
     7021 aatgaaaatt atttgtcaac aagagagggt aagtaaagat aaacttgttt aaaatagaca
     7081 gataaatcta cttccttctc ttaatttatg attcttgaaa tgcgcctgct ttaaggctaa
     7141 actagacgta tcaaagttaa gattttgttt ttgtaactgg aaagagatga acaaatcaaa
     7201 tacataaaag ataaactcat ttttattcgt ttggtaaaaa taaaatgcat atttttaaag
     7261 aaagattgat gaaaaatgta gatttgatgt ttttacttga ataaaaagcg gtttcatagt
     7321 aaaataagaa ctgagaatga tggaggtaaa tcggtggaaa atctgaagaa aatggcaggt
     7381 atcaaggctg ctgagttcgt gagcgatgga atggtcgttg gacttggaac aggctcgact
     7441 gcctattatt ttgtcgaaga aatcggtcgt cgtatcaagg aagaaggatt gcagattaca
     7501 gctgtaacaa cttctagtgt gaccactaaa caggcagaag gccttaatat cccgctcaag
     7561 tctattgacc aagtagactt tgtcgatgtg acggttgatg gcgcggatga agtggatagt
     7621 cagtttaatg gaatcaaagg cggtggtggt gcccttctca tggaaaaggt ggtcgcaaca
     7681 ccatcaaaag aatacatttg ggtggtggat gaaagcaagc tggtcgaaaa actaggtgct
     7741 tttaaattgc cagtagaagt ggttcagtat ggtgcagagc aggtctttcg tcattttgaa
     7801 cgagctggct acaaaccaag tttccgtgaa aaagacggcc aacgttttgt gacggatatg
     7861 cagaatttta tcattgacct cgccttggat gtcattgaaa atccaattgc ttttggacaa
     7921 gaattggacc atgtcgttgg tgttgtggag catggtttat tcaaccaaat ggtggataag
     7981 gtaatcgttg ctggacgaga tggagttcag atttcaactt caaaaaaagg aaaatagaag
     8041 ggggcataag atgtctaaat ttaatcgtat tcatttggtg gtactggatt ctgtaggaat
     8101 cggtgcagca ccagatgcta ataactttgt caatgcaggg gttccagatg gagcttctga
     8161 cacactggga cacatttcaa aaacagttgg tttgaatgtc ccaaacatgg ctaaaatagg
     8221 tcttggaaat attcctcgtg aaactcctct taagactgta gcagctgaaa gcaatccaac
     8281 tggatatgca acaaaattag aggaagtatc tcttggtaag gatactatga ctggacactg
     8341 ggaaatcatg ggactcaaca ttactgagcc tttcgatact ttctggaacg gattcccaga
     8401 agaaatcctg acaaaaatcg aagaattctc aggacgcaag gttattcgtg aagccaacaa
     8461 accttattca ggaacggctg ttatcgatga ttttggacca cgtcagatgg aaactggaga
     8521 gttgattatc tatacttcag ctgaccctgt tttgcagatt gctgcccacg aagacattat
     8581 tcctttggat gaattgtacc gtatctgtga atacgctcgt tcgattaccc ttgagcgtcc
     8641 tgcccttctt ggtcgcatca ttgctcgccc ttatgtaggt gaaccaggta acttcactcg
     8701 tacggcaaac cgtcgtgact tggctgtatc tccattttcc ccaactgttt tggataaatt
     8761 gaatgaggct ggtatcgata cttatgctgt gggtaaaatc aacgatatct ttaacggtgc
     8821 tggtatcaac catgacatgg gtcacaacaa gtcaaatagt catggaattg atacactatt
     8881 gaagactatg ggacttgctg agtttgaaaa aggattctca ttcacaaacc tagttgactt
     8941 tgatgccctt tacggccatc gtcgtaatgc tcacggttac cgtgattgct tgcatgagtt
     9001 tgatgaacgc ttacctgaaa ttatcgcagc tatgagagag aatgaccttc tcttgattac
     9061 tgcggaccat ggaaatgacc caacgtatgc aggaacggat cacactcggg aatatattcc
     9121 attgttggcc tatagccctg cctttaaagg aaatggtctc attccagtag gacattttgc
     9181 agatatttca gcgactgttg ccgataactt tggtgtggaa actgctatga ttggggaaag
     9241 tttcttagat aaattggtat aagatgacgc gctattcttt gctggtgaga ggtatcaatg
     9301 ttggtggtaa gaataaggtc gtcatggcgg agcttcgtca agaattgaca aacttgggac
     9361 tggaaaaggt tgagagctac atcaacagtg gcaatatttt ctttacttcg atagattcca
     9421 aagcccaatt ggttgaaaag ctagagactt tctttgcagt ccattatcca tttattcaga
     9481 gcttttcttt actgagccta gaggactttg aggcggaact tgaaaatcta ccagcttggt
     9541 ggagcagaga cttggcacga aaagattttc tcttttacac tgagggtttg gatgtggacc
     9601 aagtcatcgc gacagttgaa agtttagagc tgaaagatga agtgctttat tttggaaaac
     9661 ttgggatttt ctgggggaaa ttttctgaag aatcctattc taagactgcc tatcataagt
     9721 acttgctgaa ggtgcctttc taccgccaca ttactattcg taatgctaaa acctttgaca
     9781 aaattggtca aatgctaaaa aaataataaa ggagacacac aatgacattt ttaaacaaaa
     9841 tccatgaaac tgctactttc ctgaaagaaa agggaattgc agcccctgag ttcggtctaa
     9901 tccttggatc aggacttgga gaattggcag aagaaatcga aaatccagtt gtagtagact
     9961 atgctgagat tccaaactgg ggccgttcaa cagtagtcgg tcatgctggt aaattggtat
    10021 atggtgaact ggcaggtcgc aaggtcttgg ctcttcaagg gcgtttccat ttctatgaag
    10081 ggaatcctct ggaagtggtg actttcccag ttcgtgtgat gaaagttctt ggatgtgaag
    10141 gtgttattgt aaccaatgca gctggcggta tcggatttgg tcctggtacc ttgatggcta
    10201 tctcagacca tatcaacatg acggggcaaa atccattgat gggtgaaaac ttggatgact
    10261 ttggcccacg tttcccagat atgtctaggg cttacacacc agaataccgt gccactgccc
    10321 atgaagtggc taaaaaactt aatatcaagc ttgatgaagg tgtctatatc ggagttactg
    10381 gtccgactta tgaaacacca gcagaaattc gttcctataa gacactggga gcagatgcag
    10441 ttggtatgtc tacggttcct gaagttatcg tggcagccca ctctggcttg aaagttctgg
    10501 gaatttcatg tatcactaac tttgcggccg gtttccaaga agaactcaat cacgaagaag
    10561 ttgtagaagt gactgaacgt gttaaaggtg gtttcaaagg cttgcttaaa gcgattcttg
    10621 ctgaattgta agaaaaaaga tttaaaaggg ggagtgcctc tgtcttttca ggattgactg
    10681 cctatccgta ttaaagaaga aacagaggaa tactatgagc ttcttcctgc tcttataact
    10741 gaaagaagcg gaagaatagg tatgtctgat ctgatagcca gcattgtgaa agacaagatt
    10801 ctaggatact agcattagct tcctagccaa gcagactagt atgataagga gagatgagaa
    10861 tgaattgact ttctgaattt ctcagtctta tcatatatag cacaatgaga tttcgcttga
    10921 gtctgcttgt aaataaacga aaagaaagat aagaaataat gaaaattggt caacgaatta
    10981 tgcgctttgg cataaaaaat taagtatcgg agttgtatct gttgtagtcg gctttgattt
    11041 ctagctccag ctggaatttc agccaatgaa gtaaagcaag atgtaacatc tgaagtggta
    11101 ataggtgtgc tagattctaa ggaggaattg aaagagtcag aaaatgatgc tccaaaacta
    11161 gaaactcctc ttagagagga gccaagacta gctcctcaaa cgcttccgga agcaagtgaa
    11221 gttcttgaaa acaaaaggga agagtcaaaa gtagagataa cagagccagc tcaagcggat
    11281 gatatccgca aggttgttgg ggaattagcc aaggatataa gtattactaa gttgtatatg
    11341 acaggtcatt ctcttggagg ctacctagct cagattgcag cggttgaaga ttaccaaaaa
    11401 tatcctgatt tttataacca tgtattgagg aaagtgacaa ctttcagtgc tcctaaagtg
    11461 attacttcca gaactgtttg ggatgctaag aatggtttct gagatgttgg tttggaaagt
    11521 cgtaaattag ctgttagtgg aaaaattaag cattatgtgg ttgataatga caatgttgtg
    11581 actcccttga ttcataataa tcgtgatatt gttacattta caggtaattc acgctttaaa
    11641 caccgttctc gtggctattt tgaaagtcca atgaatgata ttcctaactt taatattggt
    11701 aaacaagcta ccttggataa acatggttat cgtgatccga aattggataa agtgcgattc
    11761 tttaagaaac aggctctacc tcaatcttct agtcaaccaa gcgctgaacc aatggaaaat
    11821 attgccttag gaaaacaggt tactcaaagt tcgacagctt tcggaggaga tgctagaaga
    11881 gctgtggatg gcaaagtcga tggtaactat ggtcacaatt ctgtcactca tacaaacttc
    11941 caatctaagc cttggtggca agtagatttg gctaaagaag aaaccattcg ccaaatcaat
    12001 atttacaacc gaacagacac tgcccaggat agattggcaa actttgatgt cattctttta
    12061 gacagttctg gtaaagaaat tgagtgaaaa cgtataatat ctcctaaaga tgtgtcagca
    12121 caaattacga ttaaccataa aaaacgcgct atgttcggat tgagctagaa ggctataatg
    12181 ccctcagtct tgcagaagtt gaagttttcc gctttatagc tacgaatgct gaaacggcga
    12241 cacaagtttc taagccagtt caaccaatca gtcagactcc tgtgaaagat aaaacattga
    12301 caattcaaca cagtggagct tacattgccc gctactccat aacttgggaa gaagttccag
    12361 tagataaaga tggaaaccaa gttgttcgta gtcattcttg ggaaggaaac ggttgcaacc
    12421 agactgcagg ttttgtcctc aacctcccaa tcaaagaaaa tatgagaaat ctgcgagtta
    12481 agattgagaa aaagacgggc ctactatgga atagatggca aacaatctat gaaaacagac
    12541 caattttagc tcaaccccac cgtaaaatta cccattgggg tacgacattg aattccaagg
    12601 tgagtgacga tgatgtcttg taatctgatg gtacaatgac agttagtttg tctagtttat
    12661 aagaaagtac tacctgagct tgaatagaac tcaggtagct ctctgtgaaa gaacaaaatt
//
LOCUS       DAVHLA010000055        12635 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVHLA010000055 DAVHLA010000000
VERSION     DAVHLA010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12635
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.055"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(94..930)
                     /locus_tag="VVO77_001860"
     CDS             complement(94..930)
                     /locus_tag="VVO77_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU5693826.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPELLKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(943..1572)
                     /locus_tag="VVO77_001861"
     CDS             complement(943..1572)
                     /locus_tag="VVO77_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU5693827.1"
                     /translation="MLELRNINKVFGDKQILSDFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASELLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(1582..2223)
                     /locus_tag="VVO77_001862"
     CDS             complement(1582..2223)
                     /locus_tag="VVO77_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU5693828.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(2369..3598)
                     /locus_tag="VVO77_001863"
     CDS             complement(2369..3598)
                     /locus_tag="VVO77_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEU5693829.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLVL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(3588..4754)
                     /locus_tag="VVO77_001864"
     CDS             complement(3588..4754)
                     /locus_tag="VVO77_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEU5693830.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            4898..5911
                     /locus_tag="VVO77_001865"
     CDS             4898..5911
                     /locus_tag="VVO77_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEU5693831.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(5956..6375)
                     /locus_tag="VVO77_001866"
     CDS             complement(5956..6375)
                     /locus_tag="VVO77_001866"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEU5693832.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(6386..7792)
                     /gene="atpD"
                     /locus_tag="VVO77_001867"
     CDS             complement(6386..7792)
                     /gene="atpD"
                     /locus_tag="VVO77_001867"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEU5693833.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(7878..8756)
                     /locus_tag="VVO77_001868"
     CDS             complement(7878..8756)
                     /locus_tag="VVO77_001868"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEU5693834.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(8772..10277)
                     /locus_tag="VVO77_001869"
     CDS             complement(8772..10277)
                     /locus_tag="VVO77_001869"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEU5693835.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(10292..10828)
                     /locus_tag="VVO77_001870"
     CDS             complement(10292..10828)
                     /locus_tag="VVO77_001870"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEU5693836.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(10828..11322)
                     /gene="atpF"
                     /locus_tag="VVO77_001871"
     CDS             complement(10828..11322)
                     /gene="atpF"
                     /locus_tag="VVO77_001871"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEU5693837.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(11336..12052)
                     /gene="atpB"
                     /locus_tag="VVO77_001872"
     CDS             complement(11336..12052)
                     /gene="atpB"
                     /locus_tag="VVO77_001872"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEU5693838.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQTIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(12087..12287)
                     /locus_tag="VVO77_001873"
     CDS             complement(12087..12287)
                     /locus_tag="VVO77_001873"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEU5693839.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            complement(12362..>12635)
                     /locus_tag="VVO77_001874"
     CDS             complement(12362..>12635)
                     /locus_tag="VVO77_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEU5693840.1"
                     /translation="NVFSEEHIYYAHPYASWERGTNENHNRLIRRWLPKGTKKMTPKE
                     VAFIEKWINNYPKKCLDYKSPREDFWMANLNLKFSKMEIIFIKRFQ"
BASE COUNT         3854 a         2815 c         2264 g         3702 t
ORIGIN      
        1 aattatccag attcaatcgc tattatcgtt ttcctagatt acaaaaaaac tacgttttgc
       61 taatcaaaac gcagtttcag ccactatttt atcttactgt ccttctttta cttctttggt
      121 tgctacatct tctccaaacc atttttggct gatttcttgg aacttgccgt ccttgtaaag
      181 actagaaaaa gcttcattta tcttcttaac caaggttgta tcttccttac gggctccaac
      241 cgcaaaagct tctgtttcta gtccaactgt aaagacatta taatcgttta aaacaccttc
      301 tgcttctaaa taatagtttg catagacacg gtcaatcaat agaccatcaa ttcgatcgtt
      361 tttcaaatca atcaaggctt cattaaaggt ttggtattga ttcgcttcct tattagcgac
      421 aatattcttc aaaagttctg gatttgcttc aaagtccgca taaccagatg aaccagcttg
      481 agctcctaat gtctttccag tcatatcctt tgcagtcgtg ataccagatg atttcttcgt
      541 aaccaatacc tgctcattct tcatatatga gttactgaaa gccacctttt cacggcgttc
      601 gtctgtagcg gaatagccat tccaaatcag atcaatcgtt ccttttgtca attcagcttc
      661 tttcaaatcc caatcaatcg gttgccaatt taccgtgatt ccgtattttt caaaaacagc
      721 tgtagctaaa tcaatatcaa atcctgcata agaaccatct ttctgagcaa atcccattgg
      781 aacaaaagta ctatcaaatc caatagtaat agacttgtta gactggtact ttgaccaatt
      841 atctccacta gtttcgctag aatttttccc acaagctact aagaacaaag cagtcatcag
      901 actgactaat acaagcatcc attttttcat ccatttttcc tcctatttag gttctacttt
      961 caataataca tctgcgatat tttcagcaaa ctgcaaatca tgggtaacca caatctgggt
     1021 catcccaagt tccctatttt gcaagattag cttctccact tccaaacgta attctggatc
     1081 cagggcagaa gttggttcat cgtagccaat gatttctggg tcaatcatca tagcacgcgc
     1141 caaagccacc cgctgctttt gcccaccaga tagtgagaaa ggataggcct ctgcgtgtcc
     1201 tcctagtcct aactgttcca agagttcact cgccttcttc tcagcctctt cctgcttcat
     1261 tcccatggtc ttcacaggcg ataaagtcaa attttccaga actgatagat gaggaaatag
     1321 ttgaaaatct tggaagacaa atcccagtag gttgcgcttc tgcaattcat ctagctctaa
     1381 aggttgtcca ttataaaaga tttgccctga atcaatggtt tcaagacctg caagcatacg
     1441 taaaagagtt gtcttacctc caccagaagg tccaacgata gccaggattt gcttttcagg
     1501 aatacttaga ctgaaatcag acaggatttg tttgtctcca aagactttat tgatatttcg
     1561 taattctaac atagctgccc cctatctata ataactatac ttcttctcaa cttttttgga
     1621 aataattgtc acaatcccaa ttaaaatcaa gtaaatggct cctgccaaga acataggaac
     1681 cagactagca tcgcggttag cagctgttcg actagccaag ataaggtctg aaattccgag
     1741 agcatagacc aaagaagtat ccttgaccaa actcataact tcattaaaga cactaggaag
     1801 aacgatcttg gtcacttggg gcaagataat atagcgcact ctgtcaaaag ggctaaactt
     1861 caagaccttg gcagcctcat actgtcctct tggaatagtg tcaattcccc cacggaaaat
     1921 ttctgcaaag taagctgcat agttgagaac aaaggcaata atagctgcag gaaggcggtc
     1981 taaacgaatc ccaatacttg ggagcacata atagataaaa atcagttgca agagtaaggg
     2041 ggttcctcgc ataacccaga tgtaaatgtt aatcagataa tggaggggct tccaatggac
     2101 ttgcaaggca aaggcaatca aaacgcccaa cggaatcgaa aatagcaaga ccagtgcaaa
     2161 gacctgtaca gtcgtgctcg caccattcag taaactcggt aatatctcaa ataaataaga
     2221 catactgcac ctcctaaaag taattgttcc tattatagca tgaataaaca agattaccaa
     2281 gtatttttgt aaaaagattc taccatatac aaataaaaac cgcagctatc aaaagagata
     2341 aactacagtt ctatatgttt aaacattctt acaatctctc aaacagttct tgcatttgca
     2401 catcatctgg aaccagtttt aagtaagtgt gagcatggac ttttgcttct tcaaaatgtc
     2461 ccaattcacg caagagatag atatagtgtt ccagaaattc tggattgtcc ttcaaatctc
     2521 ctgtcaactc ttgataatgc tcataagcag tatccaaatc gtccatttct tgataagaac
     2581 gagcaatcat ccacttggtc aaaagatttt ctggctcctc actctgcaag tctagaatat
     2641 cctcataacg ctcctgctcc agataaatag tggctaaacg aagcaagatt tcttctgtat
     2701 cctcagcgtc ttcttttgca gtaaggagat aattttctgc accactagca tcatgcaatt
     2761 cataagaaaa ttgtgaagca gctagcaaga ggcgagtttc aaagggattt ttctctaatc
     2821 cttgcttagc gatacgcagg gcttcttgaa cttgatgttc cttatgtaaa gcctgactgt
     2881 acccatactc atagccttca aagtcaggag aaatggtatc aagctgctta aagtagaggg
     2941 tggctttttg atattcttct tgatcaaaat aaagactggc caactcaaaa gctgttaagt
     3001 catcgtattc taactccagg gctttttcta aaaactcagt agccgtttca aatttcccta
     3061 actgagcata ggcaaagcca attcgttgat aggtggaaat gcccgtttgc tcataaatcg
     3121 agcgattatc taactgggca taggcttgaa tagccgcttg gtaattttcc aactcactat
     3181 ccaactctgc caaacccaat atcaagagag aatcctctga gtaggtcaag gcctccaata
     3241 atttctcacg tgccacatct gtcaaacctt ccagctggta aaggtctgcc ttcaaaacca
     3301 aagacgagac ataccagtca ctgtcagctt ggatttcctc aagataggta aaggcttctt
     3361 ctatttgacc atcctcgcta gcaattgcag ctagattaag atgaacctct ggaaaatcct
     3421 ctacaatttt caggtaaatt tccttggcct gaggatagaa accaatccct tcaagataag
     3481 ttgccaactc atacagaaga tcacttgaat cattttctaa agctttggcg aaataatgct
     3541 cagccttagt taaatcttgc tcctccaaag cctgtaacat ctgttgacta ttgttcactc
     3601 ttgacttcct caccctctaa ttcatataga ccactgacta ccttatacca ttcgaaaatg
     3661 gctgaaatga caaccttagc agaggcataa actggaatac caagtaaaac tccccagata
     3721 ccaaacatag atcctgaagt taacaaaaca aagagaacat taatagggtg gatgtttaat
     3781 tgacttccca aaatcaatgg agagacaaaa cggccttcaa tagtttgttc tacaataaag
     3841 acaatcacta ctttcaaaag catgactgga ccagcaatca aacccaatac tagggcagga
     3901 agcatggcta gaaagctacc aagataaggg accagattta aaataccagc agtaaccccc
     3961 agcgtaaccg catagcgtag accaataatc ttgaagaaga tgataaacat tactgctaca
     4021 ataatagcca ctgtcacttg ccctcgaaca tagttggaca actgttgatt cacatctgat
     4081 agaacttgtc caacaggttc cttcaatttt cttggaatga attgggtcaa atagttacgc
     4141 aagcctttcc catcacgcaa gagataaaag agcatgaaag gaacgataat caaggcaaca
     4201 atcacttgag aagccccgct aataaaggca ctcacccagt tgactgcctg agatgaaacc
     4261 ttacttgcca aaactgtagc ctggctagaa aaattggtca aaacttgctc taattgaggt
     4321 ctgaaatcat ctggcagatg ctgggctacc aatccattaa caatcctatc tatatcttct
     4381 aagtaaacag gaacgtttct tgcaaaggtc aaaacctgac gttgcagatt tggaatggcg
     4441 actgccaagc cccaaatgat aaagagagcg atgataacaa agacaatagt gatagctata
     4501 acacgattaa ccttatgctt ctccatccaa tcaacaatag gattcaacaa ataatataac
     4561 aaaccagaca aaatgactgg caacatcaca actgctaaaa agtctaaaac aggtgaaaat
     4621 agaaaactaa tcttacttaa aataaaaaga ttcaatccca ataataaggt tactaaaaat
     4681 accgtaattg ccttgttatc taaaaaccac ttgaaaaacc aagataggct aaaatgtttc
     4741 tctttttgct ccataaatac ttcctttcta ttgttctctc attataccat ttttgaaaca
     4801 aaataactct tttttaaagt gcttacatct aattgaatgt ctttaatttg cttgtttttg
     4861 tgatataata gtcttatctt tacacagagg tatagtaatg aaagaaactg tttattttgg
     4921 aacttataca cgtcgtactt ctcaagggat ttacaaggca gactttgata cagaaactgg
     4981 tcagctttca aatctagaac tttttgcagc tgagccaagt ccaacctacc ttgcctttga
     5041 ccagcaccaa catttataca ctgttggtag ccaagacgat aaggggggaa ttgcagccta
     5101 tcaaactgac gggactgtgt taaatcatgt tgttgaagaa ggagctcccc actgttatgt
     5161 tgctgtcgat gaaaagcgtg atttggttta cgcagccaac tatcacaagg gacaagtcct
     5221 tgtttataaa cgccaggaag atggtagtct tctacttagt gatatggatc aacacagtgg
     5281 ccaaggtcca catgaaaatc aagcttcccc ccatgttcac tatacagatt taacacctga
     5341 ccactatcta gtgacctgcg acttgggaac tgaccaagtc atcacctatg acctcgatca
     5401 agaaggaaaa ttatctaagc tctataccta tcacagcaag ccaggagcag gctcacgcca
     5461 tatcattttc cataaccact ataaaatcgc ttatctcatt tgtgaactca atagtactat
     5521 cgaagtttta atctacgatg gcgttggcga atttgaacgt atgcaggtca tttcaacttt
     5581 accggaagct tacgaaggct ttaatggaac cgctgctatt catctctcta aagacggtaa
     5641 atacctctac gcttctaacc gtggccatga ttctatcgca gtatatacca tccttgcgga
     5701 cggtagctta gagttattag aaatcgttcc aacgcatggt cagactccac gtgattttga
     5761 tttgacaccc gaccaaaaat ttctcattgt tgtccatcaa gactctgaca atgcaactgt
     5821 ctttaaacgt aattgtgaca atggtcgtct agcagaactc tccaacgact tccatgttcc
     5881 cgaagcagtc tgcatccgtt ttgctcctta aaacaccata aaaaatgaac ttggtatttt
     5941 caagttcatt ttttcttata gtctatttcc gacattaata cggttaatag cacgttgcaa
     6001 agcaatctta gcacgacgtt cttggtcaat caaatgtttg tcttgtgctt cttcaattgc
     6061 acgttctgca cgaagtttgg cacgttctgc acgactgata tcgatatcac gagcacgttc
     6121 tgcagagtca gcgacgattg tgatcatatc attggcaatt tcaataacac caccgtttac
     6181 tgcaatccag ttcacgtgat ctttatcatc gatacgtttt acctttactt catcaactgc
     6241 taaaactgca atcatatttt catgtcgtgg caagatcccc atctcaccat ccagagttcg
     6301 aaccgataca tagctggcat ggtgatcata gacgagacca tctggtgtca cgatctggac
     6361 agttaactga gccatagatc acctcttaaa atcccatttt ttcagctttt gcaatcacat
     6421 cttcgataga acctacacca cggaaggcat cttctggcaa gtggtcgtat ttaccatcaa
     6481 ggatttcctt aaagccacgt acagtttcag caactggaac ataagaacct ggctgaccag
     6541 taaattgttc cgcaacgttg aagttttgtg acaagaagaa ctggatacga cgggcgcgag
     6601 caaccaaggt cttttcttca tcagaaagct catccatacc aaggatagca atgatatctt
     6661 gcaattcatg gtaacgttga aggacacgtt ttacttcagc agcaactgca tagtgctctt
     6721 ctccaacgat ttcaggtgcc aaggcacgtg agcttgaagc aagtgggtca acggctgggt
     6781 agatacccaa ttgtaccaac ttacgttcca agtttgttgt tgaatccaag tgagcgaagg
     6841 ctgttgctgg cgctgggtca gtatagtcat ccgctggcac atagatagcc tggatagagg
     6901 ttacagaacc cttcttggtt gatgtgatac gttcttgcaa ttgacccatt tccgtagcaa
     6961 gtgttggttg gtaaccaacg gctgatggca tacgacccaa aagggcagat acttctgaac
     7021 cagcctgagt gaaacggaag atattatcga taaagagaag cacgtcttgg ccttccacat
     7081 cacggaagta ttcagcgatt gtcaaaccag taagggcaac acgcatacgt gctcctggtg
     7141 gctcattcat ctgaccaaag accatggctg ttttctcgat aacgcctgat tctttcattt
     7201 cccagtaaag gtcattcccc tcacgagtac gttccccaac accagcaaat actgaaatac
     7261 caccgtgctc ttgggcaatg ttgtgaatca attcttggat taagacggtt ttaccaactc
     7321 cggcaccacc gaaaagtcca actttaccac ctttaaggta aggggcaaga aggtcaataa
     7381 ccttgatccc tgtttcaagg atttcagaag aggtagacaa ctcatcaaaa gttggagctt
     7441 ttttatgaat tggctgacgc tctgcgtctt ctgtaaaagg agcttccaaa tcaatggtat
     7501 ctcccaaaac gttgaagaca cgtcccaaag tttctttacc tactggtaca gagattggac
     7561 gacctgtgtc caatacttcc attccacgag tcaacccatc tgttgattcc atggcgatag
     7621 tacgaaccat accatctcct aactccaagg ctacttcaag gacgattttt gtttttcttt
     7681 cgtcattttt gtagacgaca agtgcattgt taatctcagg aagtttttcc cctgctgcaa
     7741 acaaaacgtc tacaacggga ccgataacct gagcaatttt acctgaactc atctccttct
     7801 cctattctat ataagatact gtcggttcct agctcaacta ggtcctaagt tcattttcat
     7861 acgagctgga ctagggccta ttctaaggca ctagcacctg ctacgatttc tgtaatttct
     7921 tgtgtaatcg ccgcctgtct ggcacggtta tactgaattg tcaaatcatt gatgactttc
     7981 ttagcattat ctgtcgctgt ttgcatggct gtcatacccg cagcattctc agctgtcttg
     8041 gcatcgataa tggcaccgta aatcatactt tctgcaaact gaggcaacaa ctgctccaga
     8101 atttcttctc ggctggtttc caattcaaaa gtcaagctgt actcttcatc cgcttcattt
     8161 ggatccaagt caacaatcgg aagcatttgt tccacacgca tttgactggt tagcgtattg
     8221 acatggtggt tgtagcaaac ataaagctca tcaaagagtt cattttggta catttcaaca
     8281 gtttttgaaa taatcttacg aacttgatca aagctaggtt ggtctgccaa gccacgtaat
     8341 tcataaagtg gttgaatacc gcgagcctta aagaaatcag ctcccatccc accgatacag
     8401 atcatttcaa aacctttacc gtctgggtgg tattcttctt tcaactccat aacagctttc
     8461 aaaatagagg aattataacc tccaaccaaa ccgcggtctg aagtgataac gatatagcct
     8521 gtcttcttca cagaacggct aatcaacatc ggattagttg aagcaccagc tccattacca
     8581 tgaaggatat ctgtcaaaag tttacgcact ttctgagcgt aaacttggaa gttgcgagca
     8641 gcttcttcag agcgacctaa cttagcagcc gataccattt gcatggcatt agtgatttga
     8701 ctcgtatttt ttgttgaggc gatttttgtt ttaatatcat ttagagacac tgccatctga
     8761 cacctctatt cttattggaa gctagattga ttgagaaact ctgtaatcgc agcatccaag
     8821 actgcttctt ctggcaagtc ttttgtatca cgaatggttt ccaaaatctc tggatgttga
     8881 gcatcaaaga aggcatggaa ctcttcctcg aaacgaacaa tatcatctac tggaacagta
     8941 tccaagaaac catgtgtcaa agcataaaga atggttactt gtttctcaac aggtaatggt
     9001 ttgtgaacag gttgtttcaa gacctcaacg gtacgacgtc cacggttcaa cttagcctgt
     9061 gttgctgcgt ccaagtcaga accaaactta gtaaaggctt ccaactcacg gtatgaagca
     9121 aggtcgatac gaagtgtacc agcaaccttc ttcatggctt tgatttgtgc agaaccacct
     9181 acacgagata cagatgaacc cgcatcgatg gctggacgaa tacctgcatt gaagaggcca
     9241 tcgccaagga agatttgtcc atcagtgata gaaatcacgt tggttgcgat ataggctgag
     9301 atatctcctg cttgtgtctc gataaatggt agggctgtaa ttgatccacc accaagttca
     9361 tcagaaactt tagctgagcg ctcaagcaaa cggctgtgga gatagaaaac atcccctggg
     9421 aaggcttcac gacctggagg acgacgaagc aagagcgata gttcacgata agctaccgct
     9481 tgttttgata gatcatcgta tacaatcaaa acatgcttac cttgatacat aaattcttcc
     9541 gccatagcaa ccccagtata aggagctagg aagagcaatg gagatggttg tgaagcagag
     9601 gctgtcacaa cgattgtgta gtccaaggca ccgtactgac gaagtgtttc tacttgcgta
     9661 cgaactgttg attctttttg tccaatcgcg acgtagatac agatcatatc ttgatctttt
     9721 tggttcaaga ttgtatcaat cgcaatggtt gttttccctg tctgacggtc accgataatc
     9781 aactcacgtt gaccacgacc aatcggtaca agggcgtcaa tagctttcaa accagtttgc
     9841 aatggttctg aaacagactt acgttgcata acaccaggag ctggtgcttc tactggacga
     9901 gttttatcag tgtggatttc tccaagaccg tcaactggac gaccaagcgg atccacaaca
     9961 cgaccaatca gactttcacc tacagggact tccatgattt tccctgtacg gcggattgta
    10021 tcgccttcac ggatatctgt aaagtcacct aggatgataa taccaacgtc tgttgactcc
    10081 aagttttgag ccataccata agagccgttt tcaaaattca acaactctcc actcatgaca
    10141 ttttcaaggc catgagcacg cgcgataccg tccccgatat aggttacaac acctgtttca
    10201 gtcacatcaa aattgggttt gaaattttca atttgttgct taattaaagc gctgatttct
    10261 tgtgcgttaa ttgccaaaag aacaccactt tctatttcaa attttcttta acaactttaa
    10321 gttgttgttt aatactcaca tcaattgtct tgtgattggc aaaaatgaca aaaccaccaa
    10381 tgagactttc atcgatttgt tcttttacac tccttacttt cagagacatt tttttctcaa
    10441 tcaaagggag caaacgagtc ttctgttcat cagttagagg atgagcagac gtaatcgtca
    10501 cttcaaatcg atttgtttct ttttcaagtc ggttcaagca atctacaagc acatcataaa
    10561 aaagatttgc tctgtgattg taggccagaa cctggataaa gttttgtaat aaaggcgaca
    10621 cagaatcttg gaaaaaagca attgtttttt ccttatccga ctcgtctact gccacttgtt
    10681 ttaaaaaaga aggcagacct gttttttcaa caacttgctt gatttgagtc aagtctgaaa
    10741 agatacggtc ttcttctcct ttttcaagta ccaattggac aaaaggcatg ctgtattttt
    10801 caattacctt tactgttttc ttgtccatta agcttctcct agctgatcga tatactgatc
    10861 aatgagtgct ttatgggcat gactgtcaag gttttgtgag atgattttac cagctaagct
    10921 gatggtcaaa tctgcgacct cacccttaac actctgtaaa gcttctactt tattttgagc
    10981 aatttcttga ttggcttttt cttttaagtg tcctgcttct agtttagcat ctgctaagat
    11041 attagcctta ctttgctcag ctgtttcctt tgcattttca atgattgtct tagcttcttt
    11101 acggctacca gccaattcat cttcgcgttt ttgagccaat acttctgctt tttgacgggc
    11161 ttcttcagct ctgtcaatat ctgaagcaat tttttcagct ctttcttcga aaatgcctgt
    11221 aatattagac catgcaaatt ttttaatcaa gactagcaaa agaataaaag agccagtgat
    11281 taaaataaaa ttaccaatta attcacctac tgttacgtgc atcagttact cctttctatt
    11341 cctcttcaat attaatctta ttccctaaat acacagatgt caaaagagta aaaacataag
    11401 cttggatgca ggaaataaag acagaaaatg cagtccaagc caaattagct ccaaaggcta
    11461 ctggatacca ataaatagtt tggtgggaaa gaagaagtaa caaactcgtc atgacctctc
    11521 ctgcaaagat attcccaaaa atccgcaaag ccaaagataa gaagtttgta aattcttcca
    11581 agatattcat cggtatgaca aaaacaggac tcataaaaga ttttatactt tttttaaatc
    11641 cacgacgacg aacgctttct atatgtgtca acaaaatgac aagaaaagat aaggttaagt
    11701 catactgtaa attagcggtt ggcgaactcc accagttagt cccatcgatc gtttgaagct
    11761 ttgtcattaa gccaaggtta ttggcaatca ccatgaaaag gaataaacaa aggaaaaaga
    11821 gtgagtaatc tttcatgtag cgcgaaccaa tgttaggttc tgtaaatcca ataacaaagt
    11881 catagacata ctcaagtaca ttttgctttc ctttgggttt caaggtcata ttgcggcttg
    11941 cccaataaat aaagacaaaa ataactccca caatcaacaa agtcatggct aacatagtca
    12001 gattgaagat aacaggacca atagagatga ttggattaat actttcttcc atctaaaatc
    12061 ctcccttttc ttctcgttcc atgtatttat ttgataataa atgagaagac aagagttaca
    12121 aagaaagttc cttcaataaa ggcaacacct aaaaacatca aactacgaaa ctcagaaagc
    12181 atatctggtt ggcgtgctac tgatttaaac agtccattca tcaataaacc ttcaccgaca
    12241 gatacgccca tacaggcaat acataagcct aaaaatgtta aattcataac aaattctcct
    12301 ttaaaataaa atttacttac ttagtgtagt cctaaaattt aaatttgtca acttttaacc
    12361 gctattggaa gcgtttaata aaaattattt ccattttgct aaatttcaag ttcaagttag
    12421 ccatccagaa gtcttctctg ggtgacttgt agtccaagca ttttttagga tagttgttaa
    12481 tccacttttc gatgaatgcg acttctttgg gagtcatttt cttggttccc ttaggtaacc
    12541 atctacgaat gagcctgttg tgattctcat tagttcccct ttcccaagag gcatagggat
    12601 gtgcataata aatgtgctcc tcagaaaata catta
//
LOCUS       DAVHLA010000056        12017 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVHLA010000056 DAVHLA010000000
VERSION     DAVHLA010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12017
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.056"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(182..1813)
                     /locus_tag="VVO77_001875"
     CDS             complement(182..1813)
                     /locus_tag="VVO77_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEU5693841.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            2106..7016
                     /locus_tag="VVO77_001876"
     CDS             2106..7016
                     /locus_tag="VVO77_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEU5693842.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEAASAAKPEEKAGEVVAETPS
                     AEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKTLKPKEIKFNS
                     WEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSNTNSKAKDHAS
                     VGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLFFNWSNSIADQ
                     ERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLGEKMRQFMLYS
                     KEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPADNFFANFNWD
                     KAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGKLRLSLGLFAP
                     DTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADRTPAVGNTFTT
                     SFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAEYDFTDAYNGG
                     NSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAFSTTPDYKFDD
                     ADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYQFNLGQLTISDNHQ
                     EPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKLLTGSSSTTIY
                     LPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFEWGMTVQDTSLPRPLAENIVPG
                     ATVIGSTFPDTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKPRTVVRWVMDH
                     AGAGGESVNDGLMNTKDFDLYYKDADGKWKLAKEVRGNKAHVTDITLDKPITAQDWRL
                     NVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQVGFADVPAGA
                     TITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGKEISNVLAVSV
                     PKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIRLTHAGVSVSG
                     FDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQEPKKDYLVGDSL
                     DLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLRYQGHEVNFDVLVSP
                     KAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEAFLKAIEAAEQVLKDHETSTQDQV
                     NDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQELLAAKPNHPSGSALAPLLEKNK
                     ALVEKVDLSPEELATAKQSLKDLVALLKEDKPAVFSDSKTGVEVHFSNKEKTVIKGLK
                     VERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEKDKKVKKVFFL
                     PEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNKVLPKPTYQPA
                     SDQQKAPKLEVQEEKVAFHRQEHENTEMLVGEQRVIIQGRDGLLRHVFEVDENGQRRL
                     RSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQLPNTGTADANE
                     ALIAGLASLGLASLALTLRRKREDKD"
     gene            7106..8302
                     /locus_tag="VVO77_001877"
     CDS             7106..8302
                     /locus_tag="VVO77_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEU5693843.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            8438..8965
                     /locus_tag="VVO77_001878"
     CDS             8438..8965
                     /locus_tag="VVO77_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEU5693844.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            9042..9398
                     /gene="glnR"
                     /locus_tag="VVO77_001879"
     CDS             9042..9398
                     /gene="glnR"
                     /locus_tag="VVO77_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEU5693845.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            9435..10781
                     /gene="glnA"
                     /locus_tag="VVO77_001880"
     CDS             9435..10781
                     /gene="glnA"
                     /locus_tag="VVO77_001880"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEU5693846.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTVIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(10877..10996)
                     /locus_tag="VVO77_001881"
     CDS             complement(10877..10996)
                     /locus_tag="VVO77_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEU5693847.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            11484..12017
                     /locus_tag="VVO77_001882"
                     /pseudo
     CDS             11484..12017
                     /locus_tag="VVO77_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
BASE COUNT         3849 a         2189 c         2592 g         3387 t
ORIGIN      
        1 aacaggacaa atcgatcagg acagtcaaat cgatttctaa caatgtttta gaaatagagg
       61 tgtactattc tagtttcaat atactatata tctgcagaat actctttcag tttcattcag
      121 cctagtcttg cttaggaaaa agtaagaagc catccaatta tgatggatag cttcttggtt
      181 cttagatttg ttctgcaaaa accttttcag caaggttcat agcgtggtct gatacacgag
      241 tgtagtgtga gatgatgtcg ataaagttga ccccagcttg tgttgaacat tcgcctttgt
      301 tgaggcgttt gatgtgggtt tttctgagaa cacgttctat cttattgatt gcttcatgac
      361 gttctacaag actgcgtgct ttttcaatat cattgttttc cacactatcc agagcatctt
      421 tgataaagtc actagtttgg cggtaaactt cctctaattc tttcaaggcg gcatcagaaa
      481 attcaacatt tttccgttga agatagtcag tcagattgag tagagcctcc gtgtggtctc
      541 caatccgttc caaatcacgg gaggaatcaa ggatattggt gagcacttca ctttcttttt
      601 ggctgagagc ttcgcttgaa agggcaatga gataacgtgt taattgctca tcgatggtgt
      661 taattgcttc ttcggtttta tgcccttttt cagcaacttt ttcatccaag tcaatgatgt
      721 acttatagga aaggtcaaag gctttagcag cgtagtttcc taagtgcaag agctcttttt
      781 tagcatttcc tagagcgata gatggggctt gtttgatgaa atgttcatca agatataagg
      841 gttcgtattt gacaacctcg tcctctccag gaataatctt ggttacaaag taagccagag
      901 ctccgataaa tggaaattgg acaatggtgt tggtaatatt aaaggttccg tgagcaaagg
      961 cgatggtcat ttccggtgct agatttagcg tagcttcaaa ccaatgaatc aggacagtaa
     1021 aaggaactag aaaaataacg cagacgactg ttccgataac gttgaaggca acatgagctc
     1081 ctgctacccg tttagctgca atattagccc ctaaagaggc aatgatggct gtaatggttg
     1141 tcccgatatt gtcaccaaat agaactggca aagctccctg taggtcaatt agattgccgg
     1201 cgtagaggtt ttgtaaaatc ccaatggtag ccgaagaagc ttgaattagc aaggtcaagc
     1261 cggtaccgac aaagacaccc aaaacaggat tcttacttag ctcaatcata tagtccttaa
     1321 agacctgtaa atccttgagt ggagccattg cgccgctcat gagattgagg gcaaaaaaga
     1381 taccaccgac accaaagagg atgcgtccga tattattgac tgtccgattt ttcgtaaaaa
     1441 agagacagac ggcaccgata aagagcatag gtagggcata gttacctaat ttaaaaccga
     1501 tgagaaagga tgtgacagtt gtcccaatat tagcacccat gacaatcccg atagcctgac
     1561 gtaaggttaa gagaccggca ctgaccaggc cgactgtaat aactgttaca ccagaactag
     1621 actgaattag agcagtcatc ccaataccaa ccagaactcc aaagaaagga ttactagtat
     1681 atttgtcaat gtaaaaacga aggcgatctc cagcagcttg ttgcaaaccg tctcccatgg
     1741 tcttgatgct atataagaat agccccagac cacctaaaaa gtgaaataaa atttcctgcc
     1801 aattaatgga catttctttt tcctccgaaa aataatcgcg gaatatctcc tattctattt
     1861 taaaggataa aagtaaatct aacaagtgtt aatgtcaagt ttgtaaaaga aaattataat
     1921 tgataagtgt attattttta agagttttta accttatttt agatttgtgc aaacagttat
     1981 tgttttttgt ctaaaaatgt tttaggataa aaatgtgatt atcatggttc tagagtttga
     2041 taaaaaacta cagaatataa agcgctttct ttaaaacaac aaaatcaatc ttttaggagg
     2101 agaaaatgaa gaatccattt tttgaaagac gttgtcgtta cagtattcgt aagttatcag
     2161 taggagcctg ctcgctgatg attggtgctg ttttatttgc tggtccagcc ttggctgaag
     2221 aaactgcagt tcctgaaaat agcggagcta atacagagct tgtttcagga gagagtgagc
     2281 attcgaccaa tgaagctgat aagcagaatg aaggggaaca tgctagagaa aacaagctag
     2341 aaaaggcaga agcagctagc gcagctaaac cagaggaaaa agcaggtgag gtggttgcag
     2401 aaacaccatc tgcagaagca aaacctaagt ctgacaagga aacagaagca aagcccgaag
     2461 caactaacca aggggatgag tctaagccag cagcagaagc taataagact gaaaaagaag
     2521 tccagccaga tgtccctaaa aatacagaaa aaacattaaa accaaaggaa atcaaattta
     2581 attcttggga agaattgtta aaatgggaac caggtgctcg tgaagatgat gctattaacc
     2641 gcggatctgt tgtcctcgct tcacgtcgga caggtcattt agtcaatgaa aaagctagca
     2701 aggaagcaaa agttcaagcc ttatcaaaca ccaattctaa agcaaaagac catgcttctg
     2761 ttggtggaga agagttcaag gcctatgctt ttgactattg gcaatatcta gattcaatgg
     2821 tcttctggga aggtctcgta ccaactcctg acgttattga tgcaggtcac cgtaacgggg
     2881 ttcctgtata cggtacactc ttcttcaact ggtctaatag tattgcagat caagaaagat
     2941 ttgctgaagc tttgaagcaa gacgcagatg gtagcttccc aattgcccgt aaattggtag
     3001 acatggccaa gtattatggc tatgatggct atttcatcaa ccaagaaaca actggagatt
     3061 tggttaaacc tcttggagaa aagatgcgcc agtttatgct ctatagcaag gaatatgctg
     3121 ctaaggtaaa ccatccaatc aagtattctt ggtatgatgc catgacctat aactatggac
     3181 gttaccatca agatggtttg ggagaataca actaccaatt catgcaacca gaaggagata
     3241 aggttccggc agataacttc tttgctaact ttaactggga taaggctaaa aatgattaca
     3301 ctattgcaac tgccaactgg attggtcgta atccttatga tgtatttgca ggtttggaat
     3361 tgcaacaggg tggttcctac aagacaaagg ttaagtggaa tgacatttta gacgaaaatg
     3421 ggaaattgcg cctttctctt ggtttatttg ccccagatac cattacaagt ttaggaaaaa
     3481 ctggtgaaga ttatcataaa aatgaagata tcttctttac aggttatcaa ggagacccta
     3541 ctggtcaaaa accaggtgac aaagattggt atggtattgc taacctagtt gcggaccgta
     3601 cgccagcggt aggtaatact tttactactt cttttaatac aggtcatggt aaaaaatggt
     3661 tcgtagatgg taaggtttct aaggattctg agtggaatta tcgttcagta tcaggtgttc
     3721 ttccaacatg gcgctggtgg cagacttcaa caggggaaaa acttcgtgca gaatatgatt
     3781 ttacagatgc ctataatggc ggaaattccc ttaaattctc tggtgatgta gccggtaaga
     3841 cagatcagga tgtgagactt tattctacta agttagaagt aactgagaag accaaacttc
     3901 gtgttgccca caagggagga aaaggttcta aagtttatat ggcattctct acaactccag
     3961 actacaaatt cgatgatgca gatgcatgga aagagctaac cctttctgac aactggacaa
     4021 atgaagaatt tgatcttagc tcactagcgg gtaaaaccat ctatgcagtc aaactatttt
     4081 tcgagcatga aggtgctgta aaagattatc agtttaacct aggacaatta actatctcgg
     4141 acaatcacca agagccacaa tcgccgacaa gcttttctgt agtgaaacaa tctcttaaaa
     4201 atgcccaaga agcggaagca gttgtgcaat ttaaaggcaa caaggatgca gatttctatg
     4261 aagtttatga aaaagatgga gacagctgga aattactaac tggctcatct tctacaacta
     4321 tttatctacc aaaagttagc cgctcagcaa gtgctcaggg tacaactcaa gaactgaagg
     4381 ttgtagcagt cggtaaaaat ggagttcgtt cagaagctgc aaccacaacc tttgagtggg
     4441 ggatgactgt ccaagacaca agtcttccaa gacctctagc agaaaacatc gttccagggg
     4501 ctactgttat cggaagtacc ttcccagata cagaaggtgg agaaggtatt gaaggtatgt
     4561 tgaacggtac cattactagc ttgtcagata aatggtcttc agctcagttg agtggtagtg
     4621 tggatattcg tttgaccaag ccacgtaccg ttgttagatg ggtcatggat catgcagggg
     4681 ctggtggtga gtctgttaac gatggcttga tgaacaccaa agactttgac ctttattata
     4741 aagatgcaga tggtaagtgg aagctagcta aggaagtccg tggcaacaaa gcacacgtga
     4801 cagatatcac tcttgataaa ccaatcactg ctcaagactg gcgcttgaat gttgtcactt
     4861 ctgacaatgg aactccatgg aaggctattc gtatctataa ctggaaaatg tatgaaaagc
     4921 ttgatactga gagtgtcaat attccgatgg ccaaggctgc agcccgttct ctaggcaata
     4981 acaaggtaca agttggcttt gcagatgtac cggctggagc aactattacc gtttatgata
     5041 atccaaattc tcaaactcca ctcgcaacct tgaagagcga agttggagga gacctagcaa
     5101 gtgcaccatt ggatttgaca aatcaatctg gtcttcttta ttatcgtacc cagttgccag
     5161 gcaaggaaat tagtaatgtc ctagcagttt ccgttccaaa agatgacaga agaatcaagt
     5221 cagtcagcct agaaacagga cctaagaaaa caagctacgc cgaaggggag gatttggacc
     5281 ttagaggtgg tgttcttcga gttcagtatg aaggaggaac tgaggacgaa ctcattcgcc
     5341 taactcacgc aggtgtatca gtatcaggtt ttgatacgca tcataaggga gaacagaatc
     5401 ttactctcca atatttggga caaccagtaa atgctaattt gtcagtgact gtcactggcc
     5461 aagacgaagc aagtccgaaa actattttgg gaattgaagt aagtcaggaa ccgaaaaaag
     5521 attacctagt tggtgatagc ttagacttgt ctgaaggacg ctttgcagtg gcttatagca
     5581 atgacaccat ggaagaacat tcctttactg atgagggagt tgaaatttct ggttacgatg
     5641 ctcaaaagac tggtcgtcaa accttgacgc ttcgttacca aggtcatgaa gtcaactttg
     5701 atgttttggt atctccaaaa gcagcattga acgatgagta cctcaaacag aaattagcag
     5761 aagttgaagc tgctaagaac aaggtggtct ataactttgc ttcaccagaa gtaaaagaag
     5821 ctttcttgaa agcaattgaa gcggccgaac aagtgttgaa agaccatgaa actagcaccc
     5881 aagatcaagt caatgaccga cttaataaat tgacagaagc tcataaagct ctgaatggtc
     5941 aagagaaatt taaggaagaa aagacagaac ttgatcgctt aacaggtgag gttcaagaac
     6001 tcttggctgc caaaccaaac catccttcag gttctgccct agctccgctt cttgagaaaa
     6061 acaaggcctt ggttgaaaaa gtagatttga gtccagaaga gcttgcaaca gcgaaacaga
     6121 gtctaaaaga tctggttgct ttattgaaag aagacaagcc agcagtcttt tctgatagta
     6181 aaacaggtgt tgaagtacac ttctcaaata aagagaagac tgtcatcaag ggtttgaaag
     6241 tagagcgtgt tcaagcaagt gctgaagaga agaaatactt tgctggagaa gatgctcatg
     6301 tctttgaaat agaaggtttg gatgaaaaag gtcaagatgt tgatctctct tacgcttcta
     6361 ttgtgaaaat cccaattgaa aaagataaga aagttaagaa agtatttttc ttacctgaag
     6421 gcaaagaggc agtagaattg gcttttgaac aaacggatag tcatgttatc tttacagcac
     6481 cacactttac tcattatgcc tttgtttatg aatctgctga aaaaccacaa cctgctaaac
     6541 cagcaccaca aaacaaagtc cttccaaaac ctacttatca accggcttct gatcaacaaa
     6601 aggctcctaa attggaagtt caagaggaaa aggttgcctt tcatcgtcaa gagcatgaaa
     6661 atactgagat gctagttggg gaacaacgag tcatcataca gggacgagat ggactgttaa
     6721 gacatgtctt tgaagttgat gaaaacggtc agcgtcgtct tcgttcaaca gaagtcatcc
     6781 aagaagcgat tccagaaatt gttgaaattg gaacaaaagt aaaaacagta ccagcagtag
     6841 tagctacaca ggaaaaacca gctcaaaata cagcagttaa atcagaagaa gcaagcaaac
     6901 aattgccaaa tacaggaaca gctgatgcta atgaagccct aatagcaggc ttagccagcc
     6961 ttggtcttgc tagtttagcc ttgaccttga gacggaaaag agaagataaa gattaaatat
     7021 cgaaaaatct tgtgaaatct ttccttatat ttccaaagtg tgatataata gtttcgaata
     7081 aaataaataa aggagttttt gtaacatggc aaaacttact gttaaagacg ttgacttgaa
     7141 aggtaaaaaa gtcctcgttc gtgttgactt caacgtacca ttgaaagatg gcgtaatcac
     7201 taacgataac cgtatcacag cagctcttcc aactattaag tacatcatcg aacaaggtgg
     7261 acgtgcaatt cttttctctc accttggacg tgtgaaagaa gaagctgata aagctggtaa
     7321 atcacttgct cctgtagcag ctgacttggc agcaaaactt ggtcaagatg ttgttttccc
     7381 aggtgtcact cgtggtgctg aattggaagc ggcaatcaac gctcttgaag atggacaagt
     7441 tctcttggtt gaaaacactc gttacgaaga tgttgacggc aagaaagaat ctaaaaacga
     7501 tcctgaactt ggtaaatact gggcatcact tggagatggt atcttcgtaa acgatgcatt
     7561 cggtacagct caccgtgcac acgcatctaa cgttggtatc tcagcaaacg ttgaaaaagc
     7621 agttgctggt ttccttcttg aaaacgaaat tgcctacatc caagaagcag ttgaaactcc
     7681 agaacgtcca ttcgtggcta tccttggtgg ttcaaaagtt tcagacaaga tcggtgttat
     7741 cgaaaacttg cttgaaaaag ctgataaagt ccttatcggt ggtgggatga cttacacatt
     7801 ctacaaagca caaggtatcg aaatcggtaa ctcacttgta gaagaagaca aattggatgt
     7861 tgcgaaagct cttcttgaaa aagcaaatgg taaattgatc ttgccagttg actcaaaaga
     7921 agctaacgca tttgctggtt acactgaagt gcgtgacact gaaggtgaag cagtttctga
     7981 aggcttcctt ggtcttgaca tcggtccaaa atctatcgcc aaatttgacg aagctttgac
     8041 tggtgccaaa acagttgtat ggaacggacc tatgggtgta tttgaaaacc cagatttcca
     8101 agctggtaca atcggtgtga tggacgctat cgtgaaacaa ccaggagtta aatcaatcat
     8161 cggtggtggt gactcagctg ccgcagcgat taaccttggc cgtgcagaca agttctcatg
     8221 gattagtacg ggtggtggag catcaatgga acttcttgaa ggtaaggttc ttccaggact
     8281 tgcagccttg acagaaaaat aagattttat aaacaaatca aagaagagag ggatgaaagt
     8341 tcctcttttc ttttgcttaa aataaaaacg cttcctctca actattactc ataaaaatca
     8401 ccgatttatg ataaaatgga aatagaaagt tgagattatg agttatttta aaaaatataa
     8461 attcgataaa tcccagttca aacttggtat gcgaaccttt aaaacaggta ttgctgtttt
     8521 tctagttctc ttgatttttg gcttttttgg ctggaaaggt cttcaaattg gtgctttgac
     8581 agccgttttt agcctgaggg agagttttga tgagagtgtt cattttggga cttcgcgtat
     8641 tctaggaaat agtatcggtg gactctatgc cttggtcttc ttcttattaa ataccttttt
     8701 ccacgaagcc ttttgggtga ccttggtagt tgttccaatc tgcaccatgt taaccattat
     8761 gacaaatgta gccatgaata acaaagcagg ggttattggt ggtgtagcag ctatgttaat
     8821 cattacccta tcaattccaa gtggtgagac aatttcgtac gtgtttgtgc gtgtatcaga
     8881 aacgtttatg ggagtttttg tcgcaattat cgtaaattac gatattgatc gtattcgtct
     8941 ctttttagag aaaaaagaaa aataatgtta cattttataa cattatcaat tgacgtttgt
     9001 ctttttttag actataatag acagaaagaa ggaaattgta aatgaaggaa aaagaatttc
     9061 gccgaaatat ggctgttttt cctatcggca gtgttatgaa gttgaccgat ctatcggcgc
     9121 gtcagattcg ttattatgaa gatcaagagt tgatcaagcc cgatcgaaac gaaggaaatc
     9181 gtcgcatgta ttccttgaat gacatggatc gtctgcttga aatcaaagat tatatctctg
     9241 aaggttataa tatcgctgcc attaagaaaa aatatgctga acgtgaagcg aaatccaaga
     9301 aagcggttag tcagactgaa gtacgtcgtg cacttcacaa tgaactcctc caacaggggc
     9361 gttttgcttc agtacagtca ccttttggtc gcggttaggc aaccgcaagt agtcatagat
     9421 taaggagaaa acttatgcca atcacagctg cagatattcg tcgtgaagtc aaggaaaaaa
     9481 atgttacctt tattcgtctt atgttctcag atattttggg aaccatgaaa aacgtcgaaa
     9541 ttcctgctac agatgaacag ttagataagg tcttgtcgaa caaggttatg tttgatggat
     9601 cttctattga aggttttgta cgtatcaatg agtcggatat gtacttgtac ccggacttgg
     9661 atacatggac agtcttccct tggggagatg aaaatggaag tgttgcaggt ctgatctgtg
     9721 atgtttatac aacagaaggt gaaccatttg cgggtgaccc tcgtggtaat ttgaaacgag
     9781 ctcttcgtca catggaagaa gttggattca aatccttcaa ccttggtcca gagccagaat
     9841 tcttcctatt taagttggat gaaaatgggg acccaacact tgaagtgaat gacaagggtg
     9901 gctactttga tttggcacct actgaccttg cggacaacac acgtcgtgag attgtgaatg
     9961 tcttgaccaa aatgggattt gaagtagaag cgagtcacca cgaggttgcg gttggacagc
    10021 atgagattga ctttaagtac gatgaagttc tccgtgcttg tgataagatt caaatcttta
    10081 aacttgttgt taaaaccatt gctcgcaaac acggacttta cgcaacattt atggcgaagc
    10141 caaaatttgg tattgctgga tcaggtatgc actgtaatat gtccttgttt gatgcagaag
    10201 gaaataacgc cttctttgat ccaaatgatc caaaaggaat gcagttgtca gaaacagctt
    10261 accatttcct aggcggtttg atcaagcatg cttacaacta tactgtcatc atgaacccaa
    10321 cagttaactc atacaaacgt ttggttccag gttatgaagc gcctgtttac attgcttggg
    10381 ctggtcgtaa ccgttcgcca cttgtgcgcg tacctgcttc acgtggtatg ggaactcgtc
    10441 ttgagttgcg ttcagtggat ccaatggcga acccttacat tgctatggct gttcttttgg
    10501 aagttggttt gtatggtatt gaaaataaaa tcgaagcacc agctcctatc gaagaaaata
    10561 tctacatcat gacagcagaa gagcgcaagg aagctggtat tacagacctt ccatcaactc
    10621 ttcacaacgc tttgaaagct ttgacagaag atgaagtggt taaagctgct ctcggagatc
    10681 acatctacac tagcttcctt gaagccaaac gaatcgaatg ggcaagttat gcaaccttcg
    10741 tttcacaatg ggaaattgat aattatttag acctttacta atactaatat agaagaaaga
    10801 ttgcctgtgg gtaaacagtc acacagcagt ctaagccatc aaatacctat aacccttaaa
    10861 atagcgattt cggtcgctat ttatttttcg aaaaatcctc ttgactcttt tgcgaattag
    10921 atttatcatc agacgtgtag aagaaaatca aggagtcact atggaaaaat tcaatttcaa
    10981 aaacaatatc gggcaagaaa acaagttact tcaaatcgaa atctacaagt ttactaactt
    11041 ttgcaagctt caaaattaca catctgtaaa tattttttcg aaagatatat ttgaagccat
    11101 agtaaattga gactagaata gtacactaca tctgctaaaa atttctagaa attaatttaa
    11161 ctttcctaat cgatttgttt acatcttatt tcaatctact atattatctc aataaatgat
    11221 gatggcgact gttttgtttg tgcttgtcga tttttgaatc ctgatcgagc ggaagaatat
    11281 ttctgccgag gttgtcaagg ggaaaattct gaagatattg aattttatga tgaacaatta
    11341 caggcagaaa aggtggaggc tttgaatatt cgattggaag taaaaaattg aattatctac
    11401 aatctcatca acaataaacc tatttcaacc ccattatcta taggcgtatt tttacgcctt
    11461 tttatatact tgaagcacat aagaaacatt atgggaagtt tgctgatgga agtactcaag
    11521 aaattgatgt tccttatgat attcctgata cttgggagtg ggtgaggttt tctacattgg
    11581 ttgaaattgt cagaggtggc tctccacgac caatcaaaga ttatcttact tctgaagtag
    11641 atggaataaa ttggataaaa ataggtgata ctgaaaaggg tgaaaagtat ataaataatg
    11701 ttaaagaaaa aatcaaaaaa tcagggctta acaaaactag atttgtaaaa aaaggtacat
    11761 ttttgttaac taattctatg agttttggta gaccttatat tttgaatgtt gatggtgcaa
    11821 tacacgatgg atggttggct atttcgaact atgaaaactc attaaataaa gattatctat
    11881 tctatattct ttcatcaaat gtagtttatt ctcaatttct atctctaatt agtggagctg
    11941 ttgtgaaaaa cttgaatagt gataaagttg cttctattct tatccctctc cccccactat
    12001 ccgaacaaca acgcata
//
LOCUS       DAVHLA010000057        11220 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVHLA010000057 DAVHLA010000000
VERSION     DAVHLA010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11220
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.057"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(54..287)
                     /locus_tag="VVO77_001883"
     CDS             complement(54..287)
                     /locus_tag="VVO77_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEU5693848.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQSVGDVVKIIQGK"
     gene            complement(293..1285)
                     /gene="plsX"
                     /locus_tag="VVO77_001884"
     CDS             complement(293..1285)
                     /gene="plsX"
                     /locus_tag="VVO77_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEU5693849.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIVGLLKTAITGGGLRAKLGALLLKDSLSGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            complement(1282..2052)
                     /gene="recO"
                     /locus_tag="VVO77_001885"
     CDS             complement(1282..2052)
                     /gene="recO"
                     /locus_tag="VVO77_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEU5693850.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            complement(2049..3218)
                     /locus_tag="VVO77_001886"
     CDS             complement(2049..3218)
                     /locus_tag="VVO77_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU5693851.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLKDQAIIINGLSKSHAMTGWRLGLIFAPAAFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            3367..4377
                     /locus_tag="VVO77_001887"
     CDS             3367..4377
                     /locus_tag="VVO77_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEU5693852.1"
                     /translation="MSFLSKNGAGILACLLISIVSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVINAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKELSKFLIVMAMSAIGLKTNLVAMVKSSGKSILLGAICWIAIILTTLGMQTLIG
                     IF"
     gene            complement(4562..4999)
                     /locus_tag="VVO77_001888"
     CDS             complement(4562..4999)
                     /locus_tag="VVO77_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEU5693853.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(5084..7717)
                     /gene="polA"
                     /locus_tag="VVO77_001889"
     CDS             complement(5084..7717)
                     /gene="polA"
                     /locus_tag="VVO77_001889"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEU5693854.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNMSSADVAEGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDQLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEIKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            7970..8323
                     /locus_tag="VVO77_001890"
     CDS             7970..8323
                     /locus_tag="VVO77_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEU5693855.1"
                     /translation="MILRHLGISPTNDLVAKKIFSNPEITCQFIRDMLDLPAKNVTIL
                     EGSNIHVLPSMPYSAQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQV
                     NQNLEKIRQREGDTH"
     gene            8538..8654
                     /locus_tag="VVO77_001891"
                     /pseudo
     CDS             8538..8654
                     /locus_tag="VVO77_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
     gene            8647..8880
                     /locus_tag="VVO77_001892"
     CDS             8647..8880
                     /locus_tag="VVO77_001892"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693856.1"
                     /translation="MFSQLHMREEQVLLAQDYALETARAEGLEQGLERGKVEGRAERK
                     LFAFLDIVRQGLLTSEVASQQLGMSVSEFEALL"
     gene            9008..9150
                     /locus_tag="VVO77_001893"
                     /pseudo
     CDS             9008..9150
                     /locus_tag="VVO77_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(9287..10255)
                     /locus_tag="VVO77_001894"
     CDS             complement(9287..10255)
                     /locus_tag="VVO77_001894"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEU5693857.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(10400..11023)
                     /locus_tag="VVO77_001895"
     CDS             complement(10400..11023)
                     /locus_tag="VVO77_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEU5693858.1"
                     /translation="MPKKVLILSLLGGMFLSGWLSSFANTYIHDLLGVLFPDSPFLNA
                     FESAIVAPLVEEPLKLLSLVFVLALIPVRKLKSLFLLGIASGLGFQMIEDIGYIRTDL
                     PEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAYKGQKVGKKQGLIFLGLAL
                     GTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
BASE COUNT         3318 a         2730 c         2046 g         3126 t
ORIGIN      
        1 atatttctca tttctaaaaa ccatctactt ccgttgactt ggaactccga ttgctatttt
       61 ccttgaatga ttttaaccac atctcctaca ctttggagtt ggtcaatttc ctcatcgctg
      121 atttcgatac taaattcatc ttccagagtc aagataaact ccatcaagtc aacagaatcc
      181 gcatccaaat cgtctttcag actcaaggat tctgtcacga caaagtcctc tccctgtcgc
      241 tcttggataa tggtcacaat acggtcaaaa atttcttttt ctgtcatctc ttttattctc
      301 ctgaaaattc acgcgcagtc tgggcaacca cgtctgtttc tagcatggta cgaatctgac
      361 gaatcgtact ataaacagcc ttggcatcgc ttgagccatg agtcttgaca acaggtgcct
      421 taacaccaaa caagaccgct ccaccaacat ctgaataatt gagctgtttt ttcaaaccac
      481 tgaggctgtc cttgagaagg agggcaccta gtttcgctcg aagaccacca cctgtaatag
      541 ctgtcttgag caagcccacg attcccatag ctgtcccttc gatggatttg agcacagcgt
      601 ttcccgtgaa accatctgcc acaacaacat ctgcaacgcc attcatcaaa tcacgcgctt
      661 ccacgtttcc gataaagttc aaactttcat cagccgccag taattcataa gtttccttac
      721 gaagcgggtc gcccttgcta ctctctgttc cgttgttgag caaaccaacg cgtggttgcg
      781 caatgccacg gacattttta gcatagaagg aacctagaac cgcatattga tggaggtgct
      841 gggctgtatt ttctgcattg gcaccaaggt ctagcatgtc aaaacctttt ccatcaacgg
      901 taggcaaggt agacatgagt ccaggacggt cgatattctt gatacgaccc acgatgaaga
      961 atcctgctgc caacaaggca cctgtattcc cagccgaaag gacagcgtct gcttcaccat
     1021 ctttgacagc cttggctgcc aataccatac tggcattttt cttattccta atagctctcg
     1081 taggttcatc atccgaatca atcttctcat ccgtatggat aatgctgacg cgctctgtcg
     1141 ctgtcagata ttgcttgatt ttagcttcat ctccgtaaag ttgaacctcg atatctgaaa
     1201 agtcagatag ggcttgattg acaccctcaa caatggcctg aggtgcgtaa tcgcccccca
     1261 tggcatctac tgcgattttt ttcatttctt ttcctctttt agtaattgtc cccagtctgc
     1321 tagggaatca ataaatttct ttgattttag gtgaatccca acgtactctt catataattg
     1381 atccataaat tggcgtagct cttgcttgat tccaggcttg agcgaaatgg tctccaaagt
     1441 ctcaaaatca atagcttgaa attgattgag cagatagggg atattgggat tgagatgaca
     1501 acgtctctta tcctcatgat aatgctctgg acagaggcag gctccatatt tgaaagaaaa
     1561 gtcaaaagcc tgaccaaccc gatggcagaa gacacactca ttaaaattga ggctgattcc
     1621 aaatcgagtc aaaatttgaa tttcaaaaat attggtcaaa acctgataat ccaagcctgc
     1681 ttccatcaac tccaaagtct tttgcaaaaa agcaaacaag ggagcatcct gctgattgtc
     1741 ctgcaaacta gcatctgcaa gagctgccac ataggtcgca taggccatga caaagaggtc
     1801 actattaatc ttgggaaaag tcatgacctc atgatagtct tcgatgtaac tgagtccgtc
     1861 atcattgatt cgcaagagaa atcgtgccaa caccaagggc tgaataacag gcgccagctt
     1921 agactgacca gcgtgtttga caaaaaacat gcgtttgcca acctgctctg taaaaatttt
     1981 gacgagcttg tcatcctcac gaaaattgcg attgtaaagc accaagcctt gactcgtgat
     2041 agactgaatc atgcttctct catgtactcc tcaagtcgtt tcatggcttc tttgatagtc
     2101 tccatgctgg ctgcataaga taggcggacg tagccttccc cgtaacgtcc aaaggctgca
     2161 ccagggataa aggcaacggc cttcttctga gcaaaatcct tcagaaaagc aaaggagtct
     2221 tgattgtagc ccgctggaat tttagcaaaa atatagaagg caccgtctgg tttgataatc
     2281 tcaaaaccaa gagcagtcat tttttcgatg atatagtccc gacgctggat atattccttc
     2341 ttcatgggct ccgcatcatt tttaccagcc gtcaaggctt ctaccgcagc atgttgcgcc
     2401 atggtatttg cggcagtgac caagtattgg tgactcttga ttaactgggc tgtgaaggcc
     2461 gcaggagcga aaatcagccc caaacgccaa cctgtcatgg catgcgattt agacaaacca
     2521 ttgataataa tagcctggtc tttcaacatc gttcctagag acacatgggc ttcgcctgtg
     2581 taggtcaatt ctgagtaaac ctcatcacag acaacaaaaa tttcgtactt gcgtaaaaca
     2641 gctgccaagg cctctaactg ctctcgactg taggtaattc ctgtcggatt ggctggatag
     2701 ttgagaataa ccgctttgag cttatcaccc tgctccaaaa tggccttctc caacatctca
     2761 ggagtcaaga caaaaccatt ttcagtcgta tcaatctcaa caatttctgc cccaactaag
     2821 ttaacaatcg gttcatagcc tggataagca ggagctggca aaagtacctt gtctccctct
     2881 tccaaaatag ccgtcaaagt cgcagataaa gcctctgtcg ccccaattgt aaccaagatt
     2941 tcattttcag gagcatagtc cagttggtac ttttccttaa caaagtcact agctgcctga
     3001 cgtagagtca gcagaccact catccctgta tagtaggatt ggttctgatc aatcgctcgc
     3061 ttggccgcct ccttgacatg gtctggcgtt gtaaaatcag gttcccccaa ggtcaaacgc
     3121 aagaccccag gaatctccga aatagcctgg tcaaactgac gaatcaacga aacttgaatc
     3181 ttatctaact gtttattaaa gcgcttagtt aagtccatag atacctccta ctttcaaaac
     3241 gtatctctat tatactacaa aagcctcccg accgcaaaaa tacattagag aatagctttc
     3301 cactttctat tttacttttc ctgtttatag gtctataatg gtaatagatt ttatttggag
     3361 gtttttatgt catttctatc aaaaaatgga gcaggtatct tggcctgcct tctcatttct
     3421 atcgtatctt ggtacttagg aggattcttc cctgtgattg gcgcgcccgt ttttgccatt
     3481 ttcataggca tgctcctaca tccctttctc tcgtcctata aacaactgga tgctggtttg
     3541 acctttagtt ccaagaagtt gctccaatat gccgttgtct tgcttggttt tggtctcaat
     3601 atctcgcagg tcttcgcagt tggccaatct tcactccctg tcatcctgtc cactatctca
     3661 atagctctga ttattgccta cctcttccag cgtttctttg cactggatac aaaactggct
     3721 accttggttg gagtaggttc ttctatctgt gggggttctg ccattgcagc gacagcgccc
     3781 gttattaatg ctaaggaaaa ggaagtagcc caagccattt ccgttatctt tttcttcaat
     3841 gtcttggctg cgctcatctt tccaaccctc ggcacctggc ttcatctatc caatgaaggc
     3901 ttcgccctct ttgcagggac tgcggtcaac gacacttcct ctgtaacggc tgccgccagc
     3961 gcttgggaca gtctttacca aagcaatacc ctcgagtctg caaccattgt taaactcaca
     4021 cgtactttgg ccattatccc tatcacgctc tttctatcct actggcaaag tcgccaacaa
     4081 gaaaacaagc aaagcctaca actgaaaaaa gtcttcccac tttttatcct ttactttatc
     4141 cttgcctctc tcctcactac actactcacc tctctaggtg tgtccagtag tttctttacc
     4201 cctctcaaag aactctctaa attccttatt gtcatggcca tgagtgctat cggtctcaaa
     4261 accaatctgg tcgctatggt caaatccagt ggaaaatcca ttcttcttgg agccatctgc
     4321 tggattgcca tcatcctcac cactcttggt atgcagaccc ttatcggcat tttctaacac
     4381 tcttcgaaaa tctcttcaaa ccacgtcaac gtcgccttgc cgtaggtata tgttactgac
     4441 ttcgtcagtt ctatctgcaa cctcaaaacg gtgttttgag caacccgcag ctagtttcct
     4501 agtttgctct ttgattttca ttgagtataa cacaaaaggt agcccatcag ctaccttttt
     4561 cttatgcttc ctcaatcaag cgagtatgtt ctctcttgat acagcgattc atcacgatat
     4621 catcacatcc accatcacgc aaaatctctt ttgcttctaa actttcaagt cctagctgtg
     4681 cccaaaaaat cttggcatca gctttgagaa aatcacgcgc cacatcgggc agaaattcac
     4741 tgcgacgata aacattgaca atatctacag gaaaaggaat ttcagcgagg ctagcataag
     4801 ccttttcacc caagatttcg ccacctgccg ccttgggatt gactgggatg attttatagc
     4861 cccgagcctg catttccttt gttactcgat tgctggttgt ttcttcacgg tcagacaaac
     4921 ccaccacagc aagggtttta ctcgttgcga gatactgacg aatcacgcca tcacttggat
     4981 tgataaattc ttgactcata gaaatcctcc tttttcatca gtatagcaca ttttgaaaag
     5041 gtttgcagaa ttctactaca aaaaaggagg actagccccc tttttattta gcctcgtacc
     5101 aggttgcccc ttcattctca tctgcgataa gaggaacact gagttgaatg gcttcttcca
     5161 tggtttgttt caccaatttt tttatctcta ccaattcaga tttaggcact tcaaggacga
     5221 tttcatcgtg cacttgtaac agcatcttag tctgataacc acctgcaacc aaggctttat
     5281 ccagctgaat catggcaatc ttgagaatat ctgctgccga accctggata ggtgagttga
     5341 tagcagttcg ctccgcaaaa ccacgaatat tgaagttgcg cgaattgata tctggcaact
     5401 cacggcgacg cttaaagagg gtctctacat agcccttatc acgcgcctcc cgcaccactt
     5461 catccatgta gtttttaata cctggaaaac gttcaaagta ggtatcaatg taggctttgg
     5521 cttccttacg actaattccc aaattattag acaagccaaa gtctgaaatc ccataaacca
     5581 ctccaaagtt aactgccttg gcattgcgac ggtcatttgc agtcacatta tcaggacgct
     5641 caatgccaaa gacccgcatg gctgtcgaag tatggatatc tgccccctct tggaaggcct
     5701 taatcaagtg ctcatcctta gaaatatgcg ccaaaacgcg caattcaatc tgtgaatagt
     5761 cagagctgag tagcacacta tcctcccact ctggcacaaa agccttccga atcaagcgcc
     5821 cttgttccaa tcgggcagga atattttgca agtttggatc cacactagac aaacgcccgg
     5881 tctgggtcaa atcctgcata tagcgagtat gaatctttcc atcagccaaa atccagtcct
     5941 gcaagccaat tacataagta gattgaatct tagcaatttg acggtaatcc aggattttct
     6001 taacaatcgg agcaatagga gcgagacgct ccaacacatc cactgctgtc gaataacctg
     6061 tcttggtttt cttagtgtat tctagaggaa gtcccaattt ctcaaagaga agcacgccca
     6121 actgcttagg cgagttgaca ttaaactcct caccagccag ctcgtaaatc tcttgagtca
     6181 gtttttcaat gacaagctca ttttcagcct gcatctcaag caaggtctct ttcttgacca
     6241 caatcccagc aatttccatc ttggcaagga caaaagccag aggttgctcc atatcataaa
     6301 gaagctctaa ttgcccattt tcgctaagtt tttcaagtaa aataggctct gtttctacca
     6361 aaacagcaag tttacaagct aagtgttcca agaatttctc acgttcagga atggcctttt
     6421 taacaccctt accgtagaaa gtttcatcat caaccaagta agtctgacca taaagactag
     6481 cgatggtcgc aatttcattg tcctccacag tcgaaaggag gtatttagcc aaacggatgt
     6541 caaaagcagg cgcctgcaaa tctacaccaa aacgttgcaa aagaacttta accttcttaa
     6601 agtcataaac tctcagagat gttttttcta agaaatcctt gaaaatcggg tcttgcaaca
     6661 gctcaagctt gtctgtggca tagagctgat ccccacaaga ccaggcaaat ccaaccaaat
     6721 tatctgtatg gtaattctca ccaaaaagct caaagtggaa gatagactct tcactcagca
     6781 tatcttgact gatttggtca acaatagtaa aatccaaacc ctcagccaca tcagctgacg
     6841 acatatttaa agcctgcttg agctgtttga agcccatctc atcgtagaat ttcccaagat
     6901 tttcaacatc tggaccacta tagaccaagt cctctaaacc aatcgcaatc ggtgccttgg
     6961 tatcaatggt cgctagtgtt ttagacaaaa aggcctgttc cttgtcattg atgagatttt
     7021 ccttcatctt agaagtcttc attccatcaa tattttcata aatcccctca agcgaaccat
     7081 gctccagcaa gagcttaata cccgtctttt caccgacttt ggtcacccca gggatattat
     7141 ccgacttatc acccatgagc gccttgagat cgataaactg agctggtgtg aggcccattt
     7201 cttccatgag gtaatctggc gtaaaggcct caaactcagc cacacctttc ttggaaattt
     7261 caaccaccgt atgctcatcc gtcagctgaa tcaaatcctt gtccccactg acaatggtaa
     7321 tatcaaaacc atcctgctct gctagcttat ccagcgtccc aatgatgtca tccgcctcat
     7381 actgagccag ctcatagtga cgaatcccca tatgatccag caactcacga atgaaaggaa
     7441 attgctcacg aaactcatca ggagtcttgg cccgaccacc cttatagtcc gcatacatct
     7501 ctgtccggaa ggtcgtcttt cccgcatcaa aagccaccaa aatatgactc ggctcaaccc
     7561 gctccaacaa atgactcaac atcaactgaa aaccataaat cgcattggta tgcaaaccag
     7621 ccgcattctt aaaacggtcc aactgctgat acagcgcaaa aaacgcccga aaagctacag
     7681 aagacccatc aatcaataat aattttttct tatccataca cccattataa aggaaagaat
     7741 caaaaaatac cattgggaag agctagagca agtatttttc aaactttttc cgaataaata
     7801 gatagagcca gagaatttag taaacctaga tttaaaaatg tgctataata tagtatattg
     7861 aatctataat agtacacctt gactgctaaa atatttctat aaattaattt gactttcctg
     7921 atagagttgt tcacatctta tttcaattca ctatagaagg aggaaaagga tgattctcag
     7981 acatctggga attagcccga ccaatgactt ggttgctaag aaaattttca gcaacccaga
     8041 aatcacttgt caatttatcc gcgatatgct ggacttgcca gccaaaaatg tgactatttt
     8101 ggagggaagt aacattcatg tcttgccttc catgccctac tcagcgcagg atttttatac
     8161 cagtatagac gtcttggcgg agttggataa cggtactcaa gtaattattg agattcaagt
     8221 ccatcatcag aattttttca tcaatcactt gtgggcttac ctgtgcagtc aggttaatca
     8281 aaatcttgaa aaaattcgtc agcgagaagg tgatactcac tagatctaca aacacatcgc
     8341 tcctgtttac gtcattgcta tcgtggatag taattatttc tcagatgacc tggcttttca
     8401 tagctttagt atgcgcgaag acacaacagg tgaggtattg gcgattacca acaatggaca
     8461 ggaaaaccat ctggttaaga tggcattctt ggaattaaaa aatacagaga aaccagcaaa
     8521 gacaaggttc gcaagccatg gttggagttt ttcggcaaca agccctttac ccagcaaccg
     8581 caacgagcca ttagccaagc aaatcaactg ctggactaca agagctggtc cgaggaggac
     8641 aggaaaatgt ttagtcaact acatatgcga gaagaacaag tcttgttagc acaggactat
     8701 gccttggaaa ctgctagggc tgaaggcctt gaacaaggac tagagcgtgg gaaagttgaa
     8761 ggaagggcag aaaggaaact ttttgccttc ctagacatag tacgccaagg tcttctgact
     8821 tctgaggttg ccagccagca attaggtatg tcagtatctg aatttgaggc actgttgtaa
     8881 aatggctcca taatatccat agtgggtaaa tcccctatgg atattatgga gcctattttg
     8941 tgtaaaaaaa aaagtcccat atgacctata atgaaaagcg acaaaacaac tcattagaaa
     9001 gaatcatatg gaacaattac attttatcac aaaattacta gacattaaag accctaatgt
     9061 ccagatttta aacatcatca ataaggatac acacaaggaa agcgtcgatt caaatgctat
     9121 cactgttcaa aaatgatggt cgctgaaact tatgatgacg tacagtcata tttcttttct
     9181 ttttattata tcacagtttt aaatctagct ttactagatt caccgctact atctatttat
     9241 tcggaaaaaa gacgaaaaaa cctgagaatc atctcaggct tggtcattaa atttttttct
     9301 caatatcgaa aagtggagaa agtggtcgtt tttcatgaat acgtacgata gcatccccta
     9361 ggagatgagc gattgaaatc tgctcaatct tatcaatcaa acgctcttct ggcagataga
     9421 tggtatccaa aacaaccaat ttcttaatag ctgatttttg gatattgtcc gtagcaggac
     9481 cagaaagaac tgggtgcgta cagcttgcat agacttcaac agcaccagct tccgcaagag
     9541 catctgccgc atgacaaatc gttccagcgg tatcaatcat atcatcaatc aagatacaag
     9601 tcttgccttc aaccttaccg atgatgttca taacttcact agtattcatc ttatcaacgc
     9661 tacgacgttt atcaataata gcgatagatg ttttcaaaaa ttctgccaac ttacgagcac
     9721 gagtcacccc tccatggtcc gggctgacaa ccacatagtc agaaccaacc ataccacgac
     9781 gctcaaaata atctgcaatc agaggagcac ccatcaaatg atccacagga atatcaaaga
     9841 atccttgaat ttgcgcagca tgcaagtcga tggtcaataa acgatccact ccagctactt
     9901 caagcatatt tgcgacaagt tttgaagtga ttggctcacg cgctctcgcc tttctatcct
     9961 gacgtgcata cccatagtaa ggcatgacaa cattgacaga ttctgcactc gcacgcttca
    10021 aagcatctac cataatcaaa atttcaagca gattgtcatt tacaggcgaa ctagttgatt
    10081 gtaagataaa gacgtgtttc ccacggattg attcttcaat gttgacctga atctctccat
    10141 ctgaaaattg gcgaacactt gatttcccca actctatccc aatctcctgc gccacacgtt
    10201 ctgccaattc tttattagaa gaaagggcaa acagctttaa atcagaaaaa gacatgattt
    10261 cctccggtat atatgtatag cttgtgcttt tcacaagatt ttccatctac cattgtagcg
    10321 ctttttgcac tatttttcaa tcaaaaataa aagaagggca ccatatttgt acccttgcat
    10381 cattcttttg aaaaatattc taggtcatca actcattgtg tttctcaaca aagcaataag
    10441 catgataaaa accatagaga gcaatagccg taaccactgg aatcgctaaa ggcaactctg
    10501 tttccaactc cacaaaagga gagttaaaca agaagtgagt tcccaaggct aaacctagaa
    10561 aaataaggcc ctgtttcttg ccaaccttct gtcctttata ggctctgtaa agcaagtaaa
    10621 cacctactac agctagacct gaaaaagtcc agtgagaggc aattcctgag atgatacgct
    10681 ctaaaattcg cgaaatagta aagtcaaagc cctctggcaa atccgtacga atataaccaa
    10741 tatcctcaat catttggaat cccaaaccgg aagcaattcc aagtaaaaac aaagatttta
    10801 attttcgcac aggaatcaaa gccaaaacaa aaacaagtga caataatttc aagggttctt
    10861 ctaccaaagg agccacaata gcactttcaa aggcatttaa aaatggacta tctgggaaaa
    10921 gaacccccag taaatcatgg atataagtat tagcaaaact agacaaccag cctgaaagga
    10981 acatccctcc caataaagac agaatcaaaa ccttctttgg caattcccat ttttcccaat
    11041 acggaagaga aaataaagag ccggaatcat gtaaaagaga gctagaaaga tagaaactcc
    11101 cattagtcca tattccgcac ctgacctcga accgtccgta tagtagatgg tttcatactg
    11161 taaaccaata catagcaata aaataaaaat aaataaaata ctgcttttct tcatacactt
//
LOCUS       DAVHLA010000058        11191 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVHLA010000058 DAVHLA010000000
VERSION     DAVHLA010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11191)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11191)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11191
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.058"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            54..1169
                     /gene="ychF"
                     /locus_tag="VVO77_001896"
     CDS             54..1169
                     /gene="ychF"
                     /locus_tag="VVO77_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEU5693859.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLIESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYESEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            1240..1809
                     /locus_tag="VVO77_001897"
     CDS             1240..1809
                     /locus_tag="VVO77_001897"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEU5693860.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     KADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            1810..5319
                     /gene="mfd"
                     /locus_tag="VVO77_001898"
     CDS             1810..5319
                     /gene="mfd"
                     /locus_tag="VVO77_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEU5693861.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERDLAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTNICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKEFKEENSI"
     gene            5387..5653
                     /locus_tag="VVO77_001899"
     CDS             5387..5653
                     /locus_tag="VVO77_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEU5693862.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            5646..6014
                     /locus_tag="VVO77_001900"
     CDS             5646..6014
                     /locus_tag="VVO77_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEU5693863.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            6134..7402
                     /locus_tag="VVO77_001901"
     CDS             6134..7402
                     /locus_tag="VVO77_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEU5693864.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKAWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            7399..8676
                     /gene="tilS"
                     /locus_tag="VVO77_001902"
     CDS             7399..8676
                     /gene="tilS"
                     /locus_tag="VVO77_001902"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEU5693865.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPKLEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKTQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ELIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            8680..9222
                     /gene="hpt"
                     /locus_tag="VVO77_001903"
     CDS             8680..9222
                     /gene="hpt"
                     /locus_tag="VVO77_001903"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEU5693866.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEVDYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            9238..>11191
                     /gene="ftsH"
                     /locus_tag="VVO77_001904"
     CDS             9238..>11191
                     /gene="ftsH"
                     /locus_tag="VVO77_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEU5693867.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMFGAQNPQKS
                     ISEQTAYEIDEEVRSLLNKARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDE"
BASE COUNT         3857 a         1658 c         2310 g         3366 t
ORIGIN      
        1 ccctttttgt gttataatat tagggattga aatgaaaacg gagaatgaga aatatggctt
       61 tgacagcagg tatcgttggt ttgccaaacg ttggtaaatc aacactattt aatgcaatta
      121 caaaagcagg agcagaggca gcaaactacc catttgcgac tattgatcca aatgttggaa
      181 tggtggaagt tccagatgaa cgcctacaaa aactaactga aatgataact cctaaaaaga
      241 cagttcccac aacatttgaa tttacggata ttgcagggat tgtaaaagga gcttcaaaag
      301 gagaagggct agggaataaa ttcttggcca atattcgtga agtagatgcg attgttcacg
      361 tagttcgtgc ttttgatgat gaaaatgtga tgcgcgagca aggacgtgaa gacgcctttg
      421 tggatccact tgcagatatt gacaccatta acctagaatt gattcttgca gacttagaat
      481 cagtcaataa acgatatgcg cgtgtagaaa agatggcacg tacgcaaaaa gataaagaat
      541 cagtagcaga attcaatgtt cttcaaaaga ttaaaccagt cctagaagac gggaaatcag
      601 ctcgtaccat tgaatttaca gatgaggaac aaaaggttgt caaaggtctt ttccttttga
      661 cgactaaacc agttctttat gtagctaatg tggacgagga tgtggtttca gaacctgact
      721 ctatcgacta tgtcaaacaa attcgtgaat ttgcagcgac agaaaatgct gaagtagtcg
      781 ttatttctgc gcgtgctgag gaagaaattt ctgaattgga tgatgaagat aaaaaagagt
      841 ttcttgaagc cattggtttg atagaatcag gtgtagataa gttgacgcgt gcagcttacc
      901 acttgcttgg attgggaact tacttcacag ctggtgaaaa agaagttcgc gcttggactt
      961 tcaaacgtgg tatgaaggct cctcaagcag ctggtattat ccactcagac tttgaaaaag
     1021 gctttattcg tgcagtaacc atgtcatatg aggatctagt gaaatacgaa tctgaaaagg
     1081 ccgtaaaaga agctggacgc ttgcgtgaag aaggaaaaga atatatcgtt caagatggcg
     1141 atatcatgga attccgcttt aatgtctaaa aattaataaa tggtgtcaat taggttggaa
     1201 aaaaattcca acccttttgg cttttgaaag gaaaaataaa tgaccaaatt acttgtaggc
     1261 ttgggaaatc caggggataa atattttgaa acaaaacaca atgttggttt tatgttgatt
     1321 gatcaactag cgaagaaaca gaatgtcact tttacacacg ataagatatt taaagctgac
     1381 ctagcatcct ttttcctaaa tggagaaaaa atttatctgg ttaaaccaac gacctttatg
     1441 aatgaaagtg gaaaagcagt tcatgcttta ttaacttact atggtttgga tattgacgat
     1501 ttacttatca tttacgatga tcttgacatg gaagttggga aaattcgttt aagagcaaaa
     1561 ggctcagcag gtggtcataa tggtatcaag tctattattc aacatatagg aactcaggtc
     1621 tttaaccgtg ttaagattgg aattggaaga cctaaaaatg gtatgtcagt tgttcatcat
     1681 gttttgagta agtttgacag ggatgattat atcggtattt tacagtctgt tgacaaagtt
     1741 gacgattctg taaactacta tttacaagag aaaaattttg agaaaacaat gcagaggtat
     1801 aacggataaa tggtgacctt attagattta ttctcagaaa atgatcagat taaaaaatgg
     1861 catcaaaatt taactgataa gaaaagacaa ctaatacttg gtttatcaac atctactaag
     1921 gctcttgcaa ttgcaagcag tttagaaaaa gaagatagga ttgtgttatt gacgtcaact
     1981 tatggagaag cagaaggact tgttagtgat cttatatcta tcttgggtga ggaactcgtc
     2041 tatccatttt tggtagatga tgctcctatg gtggagtttt tgatgtcttc acaggaaaaa
     2101 attatttcac gggttgaagc cttgcgtttt ttgactgatt catctaagaa agggatttta
     2161 gtttgtaata tcgcagcaag tcgattgatt ttaccgtctc ccaatgcatt caaagatagt
     2221 attgtaaaaa tctcagttgg tgaagaatat gatcaacacg cgtttatcca tcagttaaag
     2281 gaaaatggct atcgaaaagt tactcaagta caaactcagg gcgaatttag tcttcgagga
     2341 gatattttag atatttttga aatatcccag ttagaacctt gtcgaattga gttttttggt
     2401 gatgaaattg atggtatcag gtcatttgaa gtagaaacac aattatcgaa agaaaataag
     2461 acagaactca ctatctttcc agctagtgat atgcttttga gagaaaagga ttatcaacga
     2521 ggacagtcag ctttagaaaa acaaatttca aaaactttat cacctatttt gaaatcatac
     2581 ctagaagaaa ttctttcaag ttttcaccaa aaacaaagtc atgcagactc tcggaagttt
     2641 ttatctttgt gctatgataa gacatggact gtctttgatt atattgaaaa agatactcca
     2701 atattctttg atgattatca aaaattgatg aatcagtatg aagtctttga aagagactta
     2761 gcgcagtact ttacagaaga attacagaat agtaaagcat tttctgatat gcagtatttt
     2821 tctgatattg aacaaatcta taaaaaacaa agtccagtga cctttttctc taatcttcaa
     2881 aagggtttag gaaatctcaa atttgacaaa atttatcaat tcaatcaata tcctatgcag
     2941 gaatttttca atcagttttc ttttctaaaa gaagaaattg aacgatataa aaaaatggat
     3001 tacaccatta ttctgcagtc tagcaattca atgggaagta aaacattgga ggatatgtta
     3061 gaggaatatc agattaaatt ggattctaga gataagacaa atatctgtaa agaatctgta
     3121 aacttaatag agggtaatct cagacatggt tttcattttg tagatgaaaa gattttattg
     3181 ataactgaac atgagatttt tcaaaagaaa ttaaagcgtc gttttcgaag acaacatgtt
     3241 tcaaatgcag agagattaaa agattacaat gaacttgaaa aaggggacta tgttgtccat
     3301 catatccatg ggattggtca atatctagga attgaaacca ttgaaatcaa gggaattcat
     3361 cgcgattatg tcagtgtcca ataccaaaat ggtgatcaaa tttctatccc cgtggaacag
     3421 attcatctac tgtccaaata tatttcaagt gatggtaaag ctccaaaact caataaatta
     3481 aatgacggtc attttaaaaa ggccaagcaa aaggttaaga accaggtaga ggatatagct
     3541 gatgatttaa tcaaactcta ctctgaacgt agtcagttga agggttttgc tttctcagct
     3601 gatgatgatg atcaagatgc ctttgatgat gctttccctt atgttgaaac ggatgatcaa
     3661 cttcgtagta ttgaggaaat caaaagggat atgcaggctt ctcagccaat ggatcgactt
     3721 ttagttgggg atgttggttt tggaaagact gaagttgcta tgcgtgcagc ctttaaagca
     3781 gtcaatgatc acaaacaggt tgtcattcta gttccgacga cggttttagc gcaacagcac
     3841 tatacgaatt ttaaggaacg attccaaaat tttgcagtta atgttgatgt gttgagtcgc
     3901 tttagaagta aaaaagagca gactgcaaca cttgaaaaat tgaaaaacgg tcaagtcgat
     3961 attttgattg gaacacatcg tgttttgtca aaagatgttg tgtttgctga tttgggcttg
     4021 atgattattg atgaggaaca gcgatttggt gtcaagcata aggaaacttt gaaagaactg
     4081 aagaaacaag tggatgtcct aaccttgacc gctacgccaa tccctcgtac cctccatatg
     4141 tctatgctgg gaatcagaga tttgtctgtt attgaaactc cgccgactaa tcgctatcct
     4201 gttcagacct atgttttgga aaagaatgat agtgtcattc gtgatgctgt cttgcgtgaa
     4261 atggagcgtg gaggtcaagt ttactatctt tacaacaaag ttgacacaat tgttcagaag
     4321 gtttcagaat tacaggagtt gattccggag gcttcgattg gatatgttca tggtcgaatg
     4381 agtgaagtcc agttggaaaa tactctatta gactttattg agggacaata cgatatcttg
     4441 gtgacgacta ctattattga gacaggggtg gacattccaa atgctaatac tttatttatt
     4501 gaaaatgcgg accatatggg cttgtcaacc ttatatcagt taagaggaag agtcggtcgt
     4561 agtaatcgta ttgcttatgc ttatctcatg tatcgtccag aaaaatcaat cagtgaagtc
     4621 tctgaaaaga gattagaagc gattaaagga tttacagaat tgggctctgg ctttaagatt
     4681 gcaatgcgag atctttcgat tcgtggagca ggaaatcttt taggaaaatc ccagtctggt
     4741 ttcattgatt ctgttggttt tgaattgtat tcgcagttat tagaggaagc tattgctaaa
     4801 cgaaacggta atgctaacgc taacacaaga accaaaggga atgctgagtt gattttgcaa
     4861 attgatgcct atcttcctga tacttatatt tctgatcaac gacataagat tgaaatttac
     4921 aagaaaattc gtcaaattga caaccgtgtc aattatgaag agttacaaga ggagttgata
     4981 gaccgttttg gagaataccc agatgtagta gcctatcttt tagagattgg tttggtcaaa
     5041 tcatacttgg acaaggtctt tgttcaacgt gtggaaagaa aagataataa aattacaatt
     5101 caatttgaaa aagtcactca acgactgttt ttagctcaag attattttaa agctttatcc
     5161 gtaacgaact taaaagcagg catcgctgag aataagggat taatggagct tgtatttgat
     5221 gtccaaaata agaaagatta tgaaatttta gaaggtctgc tgatttttgg agaaagttta
     5281 ttagagataa aagagtttaa ggaagaaaat tccatttgat atttttcttc tataaaatag
     5341 ataaaaatag ataaaaatgg tacaataata aattgaggta ataaggatga gattagataa
     5401 atatttaaaa gtatcgcgaa ttatcaagcg tcgtacagtc gcaaaggaag tagcagataa
     5461 aggtagaatc aaggttaatg gaatcttggc caaaagttca acggacttga aagttaatga
     5521 ccaagttgaa attcgctttg gcaataagtt gctgcttgta aaagtactag agatgaaaga
     5581 tagtacaaaa aaagaagatg cagcaggaat gtatgaaatt atcagtgaaa cacgggtaga
     5641 agaaaatgtc taaaaatatt gtacaattga ataattcttt tattcaaaat gaataccaac
     5701 gtcgtcgcta cctgatgaaa gaacgacaaa aacggaatcg ttttatgggg ggggtattga
     5761 ttttgattat gctattattt atcttgccaa cttttaattt ggcgcagagt tatcagcaat
     5821 tactccaaag acgtcagcaa ttagcagact tgcaaactca gtatcaaact ttgagtgatg
     5881 aaaaggataa ggaaacagca tttgctacca agttgaaaga tgaagattat gctgctaaat
     5941 atacacgagc gaagtactat tattctaagt cgagggaaaa agtttatacg attcctgact
     6001 tgcttcaaag gtgataaaat ggaaaattta ttagacgtaa tagagcaatt tttgagtttg
     6061 tcagatgaaa agctggaaga attgactgat aaaaatcaat tattgcgttt acaagaagaa
     6121 aaggaaagga agaatgcgta aattcttaat tattttgttg ctaccaagtt ttttgaccat
     6181 ttcaaaagtc gttagcacag aaaaagaagt cgtctatact tcgaaagaaa tttattacct
     6241 ttcacaatct gactttggta tttattttag agaaaaatta agttctccca tggtttatgg
     6301 agaggttcct gtttatgcga atgaagattt agtagtggaa tctgggaaat tgactcccaa
     6361 aacaagtttt caaataaccg agtggcgctt aaataaacaa ggaattccag tatttaagct
     6421 atcaaatcat caatttatag ctgcggacaa acgattttta tatgatcaat cagaggtaac
     6481 tccaacaata aaaaaagcat ggttagaatc tgactttaaa ctgtacaata gtccttatga
     6541 tttaaaagaa gtgaaatcat ccttatcagc ttattcgcaa gtatcaatcg acaagaccat
     6601 gtttgtagaa ggaagagaat ttctacatat tgatcaggct ggatgggtag ctaaagaatc
     6661 aacttctgaa gaagataatc ggatgagtaa agttcaagaa atgttatctg aaaaatatca
     6721 gaaagattct ttctctattt atgttaagca actgactact ggaaaagaag ctggtatcaa
     6781 tcaagatgaa aagatgtatg cagccagcgt tttgaaactc tcctatctct attatacgca
     6841 agaaaaaata aatgagggtc tttatcagtt agatacgact gtaaaatacg tatctgcagt
     6901 caatgatttt ccaggttctt ataaaccaga gggaagtggt agtcttccta aaaaagaaga
     6961 taataaagaa tattctttaa aggatttaat tacgaaagta tcaaaagaat ctgataatgt
     7021 agctcataat ctattgggat attacatttc aaaccaatct gatgccacat tcaaatccaa
     7081 gatgtctgcc attatgggag atgattggga tccaaaagaa aaattgattt cttctaagat
     7141 ggccgggaag tttatggaag ctatttataa tcaaaatgga tttgtgctag agtctttgac
     7201 taaaacagat tttgatagtc agcgaattgc caaaggtgtt tctgttaaag tagctcataa
     7261 aattggagat gcggatgaat ttaagcatga tacgggtgtt gtctatgcag attctccatt
     7321 tattctttct attttcacta agaattctga ttatgatacg atttctaaga tagccaagga
     7381 tgtttatgag gttctaaaat gagggaacca gattttttaa atcattttct caagaaggga
     7441 tatttcaaaa agcatgctaa ggcggttcta gctctttctg gtggattaga ttctatgttt
     7501 ctatttaagg tattgtctac ttatcaaaaa gagttagaga ttgaattgat tctggctcat
     7561 gtgaatcata agcagagaat tgaatcagat tgggaagaaa aggaattaag gaagttggct
     7621 gctgaagcag agcttcctat ttatatcagc aatttttcag gagaattttc agaagcgcgt
     7681 gcacgaaatt ttcgttatga tttttttcaa gaggtcatga aaaagacagg tgcgacagct
     7741 ttagtcactg cccaccatgc tgatgatcag gtggaaacga ttttgatgcg cttgattcga
     7801 ggaactcgct tgcgctatct atcaggaatt aaggagaagc aagtagtcgg agagatagaa
     7861 atcattcgtc ccttcttgca ttttcagaaa aaagactttc catcaatttt tcactttgaa
     7921 gatacatcaa atcaggagaa tcattatttt cgaaatcgta ttcgaaattc ttacttacca
     7981 aaattggaaa aagaaaatcc tcgatttagg gatgcaatct taggcattgg caatgaaatt
     8041 ttagattatg atttggcaat agctgaatta tctaacaata ttaatgtgga agatttacag
     8101 cagttatttt cttactctga gtctacacaa agagttttac ttcaaactta tctgaatcgt
     8161 tttccagatt tgaatcttac aaaaactcag tttgctgaag ttcagcagat tttaaaatct
     8221 aaaagccagt atcgtcatcc gattaaaaat ggctatgaat tgataaaaga gtaccaacag
     8281 tttcagattt gtaaaatcag tccgcaggct gatgaaaagg aagatgaact tgtgttacac
     8341 tatcaaaatc aggtagctta tcaaggatat ttattttcct ttggacttcc attagaaggt
     8401 gaattaattc aacaaatacc tgtttcacgt gaaacatcca tacacattcg tcatcgaaaa
     8461 acaggagatg ttttgattca aaatgggcat agaaaaaaac tcagacgttt atttattgat
     8521 ttgaaaatcc ctatggaaaa gagaaactct gctcttatta ttgagcaatt tggtgaaatt
     8581 gtctcaattt tgggaattgc gaccaataat ttgagtaaaa aaacgaaaaa tgatataatg
     8641 aacactgtac tttatataga aaaaatagat aggtaaaaaa tgttagaaaa cgatattaaa
     8701 aaagtcctcg tttcacacga tgaaattaca gaagcagcta aaaaactagg tgctcaatta
     8761 actaaagact atgcaggaaa aaatccaatc ttagttggga ttttaaaagg atctattcct
     8821 tttatggctg aattggtcaa acatattgat acacatattg aaatggactt catgatggtt
     8881 tctagctacc atggtggaac agcaagtagt ggtgttatca atattaaaca agatgtgact
     8941 caagatatca aaggaagaca tgttctattt gtagaagata tcattgatac aggtcaaact
     9001 ttgaagaatt tgcgagatat gtttaaagaa agagaagcag cttctgttaa aattgcaacc
     9061 ttgttggata aaccagaagg acgtgttgta gaaattgagg tagactatac ctgctttact
     9121 atcccaaatg agtttgtagt aggttatggt ttagactaca aagaaaatta tcgtaatctt
     9181 ccttatattg gagtattgaa agaggaagtg tattcaaatt agaaagaata atctttaatg
     9241 aaaaaacaaa ataatggttt aattaaaaat ccttttctat ggttattatt tatctttttc
     9301 cttgtgacag gattccagta tttctattct gggaataact caggaggaag tcagcaaatc
     9361 aactatactg agttggtaca agaaattacc gatggtaatg taaaagaatt aacttaccaa
     9421 ccaaatggta gtgttatcga agtttctggt gtctataaaa atcctaaaac aagtaaagaa
     9481 ggaacaggta ttcagttttt cacgccatct gttactaagg tagagaaatt taccagcact
     9541 attcttcctg cagatactac cgtatcagaa ttgcaaaaac ttgctactga ccataaagca
     9601 gaagtaactg ttaagcatga aagttcaagt ggtatatgga ttaatctact cgtatccatt
     9661 gtgccatttg gaattctatt cttcttccta ttctctatga tgggaaatat gggaggaggc
     9721 aatggccgta atccaatgag ttttggacgt agtaaggcta aagcagcaaa taaagaagat
     9781 attaaagtaa gattttcaga tgttgctgga gctgaggaag aaaaacaaga actagttgaa
     9841 gttgttgagt tcttaaaaga tccaaaacga ttcacaaaac ttggagcccg tattccagca
     9901 ggtgttcttt tggagggacc tccggggaca ggtaagactt tgcttgctaa ggcagtcgct
     9961 ggagaagcag gtgttccatt ctttagtatc tcaggttctg actttgtaga aatgtttgtc
    10021 ggagttggag ctagtcgtgt tcgctctctt tttgaggatg ccaaaaaagc agcaccagct
    10081 atcatcttta tcgatgaaat tgatgctgtt ggacgtcaac gtggagttgg tctcggcgga
    10141 ggtaatgacg aacgtgaaca aaccttgaac caacttttga ttgagatgga tggttttgag
    10201 ggaaatgaag ggattatcgt catcgctgcg acaaaccgtt cagatgtact tgatcctgcc
    10261 cttttgcgtc caggacgttt tgatagaaaa gtattggttg gccgtcctga tgttaaaggt
    10321 cgtgaagcaa tcttgaaagt tcacgctaag aacaagcctt tagcagaaga tgttgatttg
    10381 aaattagtgg ctcaacaaac tccaggcttt gttggtgctg atttagagaa tgtcttgaat
    10441 gaagcagctt tagttgctgc tcgtcgcaat aaatcgataa ttgatgcttc agatattgat
    10501 gaagcagaag atagagttat tgctggacct tctaagaaag ataagacagt ttcacaaaaa
    10561 gaacgagaat tggttgctta ccatgaggca ggacatacca ttgttggtct agtcttgtcg
    10621 aatgctcgcg ttgtccataa ggttacaatt gtaccacgcg gccgtgcagg cggatacatg
    10681 attgcacttc ctaaagagga tcaaatgctt ctatctaaag aagatatgaa agagcaattg
    10741 gctggcttaa tgggtggacg tgtagctgaa gaaattatct ttaatgtcca aactacagga
    10801 gcttcaaacg actttgaaca agcgacacaa atggcacgtg caatggttac agagtacggt
    10861 atgagtgaaa aacttggccc agtacaatat gaaggaaacc atgctatgtt tggtgcacag
    10921 aatcctcaaa aatcaatttc agaacaaaca gcttatgaaa ttgatgaaga ggttcgttca
    10981 ttattaaata aggcacgaaa taaagctgct gaaattattc agtcaaatcg tgaaactcac
    11041 aagttaattg cagaagcatt attgaaatac gaaacattgg atagtacaca aattaaagct
    11101 ctttacgaaa caggaaagat gcctgaagca gtagaagagg aatctcatgc actatcctat
    11161 gatgaagtaa agtcaaaaat gaatgacgaa a
//
LOCUS       DAVHLA010000059        11187 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVHLA010000059 DAVHLA010000000
VERSION     DAVHLA010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11187)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11187)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11187
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.059"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(<1..627)
                     /locus_tag="VVO77_001905"
     CDS             complement(<1..627)
                     /locus_tag="VVO77_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU5693868.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     TLIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDM"
     gene            1251..1373
                     /locus_tag="VVO77_001906"
     CDS             1251..1373
                     /locus_tag="VVO77_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEU5693869.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAG"
     gene            1443..1808
                     /locus_tag="VVO77_001907"
     CDS             1443..1808
                     /locus_tag="VVO77_001907"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEU5693870.1"
                     /translation="MPNSESTKPKTFEIDCLVGKKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYYGDSAWEHLRAVTGI
                     DLLSILTDIANKKTGVKSK"
     gene            1805..2995
                     /locus_tag="VVO77_001908"
     CDS             1805..2995
                     /locus_tag="VVO77_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEU5693871.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGSDM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
     gene            complement(3510..4502)
                     /locus_tag="VVO77_001909"
     CDS             complement(3510..4502)
                     /locus_tag="VVO77_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU5693872.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            4662..6416
                     /locus_tag="VVO77_001910"
     CDS             4662..6416
                     /locus_tag="VVO77_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5693873.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISALLTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNEGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            6400..8121
                     /locus_tag="VVO77_001911"
     CDS             6400..8121
                     /locus_tag="VVO77_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5693874.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            8132..8761
                     /locus_tag="VVO77_001912"
     CDS             8132..8761
                     /locus_tag="VVO77_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEU5693875.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYIVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFSNGLYCVGYFTPCLILWCYLN"
     gene            8662..9219
                     /locus_tag="VVO77_001913"
     CDS             8662..9219
                     /locus_tag="VVO77_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU5693876.1"
                     /translation="MYRQGSIEKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIP
                     IVIRMFILPFMAASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKN
                     IKMAMRVRGINFKNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRV
                     KIQLIDFVYVLAVAGLIVGGLIWLK"
     gene            9207..10571
                     /locus_tag="VVO77_001914"
     CDS             9207..10571
                     /locus_tag="VVO77_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU5693877.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKNSPFVFFDEPSSGMDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
     gene            complement(11026..11184)
                     /locus_tag="VVO77_001915"
     CDS             complement(11026..11184)
                     /locus_tag="VVO77_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HEU5693878.1"
                     /translation="MSLLETAKRHQLNSEKYLSYLLECLPNEETLVNKEVLEAYLPWT
                     KVVQEKCK"
BASE COUNT         4101 a         1568 c         1900 g         3618 t
ORIGIN      
        1 catgtcgtaa aggtcgtatt tccaacggca tgactgagaa catccaccac ggttggcatc
       61 acgcatactc atgtggtttg aaagagtaca acgtccagag tatgaaatac acatagctcc
      121 atggacaaag gcttcaattt caacatctgt acgtttgcgg atttcagcta attcttccat
      181 tgaaacctca cgcgctaaaa cgacacgagt caagcctagc tctttccaga actcaagggt
      241 ttcatagtta gtggcactgg cttgggtaga aaggtggatt tcaaggcctg gtgcttcagt
      301 cgctgcaatc ataatcaagg ttgggtcaga tacgataact gctgcaatcc cgatatcacg
      361 cagtttacgg aaccactcac cagcaccagc ttcatttcct tcgtgcataa ccatattagc
      421 cgctacatag accttggcac catacttggc cgcaaactgc acgccttctt ccatctgttc
      481 gaaagtaaag tttcccgcac ggctacgaag accataggcc tgaccaccga taaagacagc
      541 atctgctcca tactgaacag ctacctttag cttctctaaa gtccctgcag gtgataaaac
      601 ctcaggacgt tttaatgttt ttgtcataat ttctcctatt tgcaatataa aagtttgaca
      661 tttttccttc tcattttata gtaaataaag gataaaatca agcctagacg gattgttttg
      721 acaattctaa tcttttagac tttgcataat aactgttaaa cagtcgaaaa ttatcccagt
      781 tttaacaagt agtcaaaaag tctagaaaag taaaaaccag tatccaaaga tactgactcg
      841 taaaaataca taaattagtc cttagatgac tactcccact ctgttgctcc tataatggaa
      901 aaggattgat acagtctaga atatcgcttt tttatttatt attctgatat aaaactgtta
      961 gaattgattt tttgttttat acccaaatat gaatagagac gtagctaata agttgaataa
     1021 catatttgga aaaatgagaa atagcaatat tactagaact tttagaaaca atcaatattt
     1081 aaaaagaaaa aagctcaaag aatttattaa accatgttat aatagatata gctataattt
     1141 tatttataac aagaggatag aaatgaccga attagaaaga aaaaatcgaa aaattagcta
     1201 agaaatattc tgataactta aacatcaaag ttcaagagag agttcgtgaa atggcaaatg
     1261 ataataagag ccattatttg atatacagag ttttaggtat ttcatttgaa gaaggagaaa
     1321 atatcgattt gtatcaaaat aaaggtcgtt ttttatacaa atatgctggt taatttttag
     1381 aagaagctgc agtactatcc tttaacgaaa aatttggtac agaaaatact taaaaagtta
     1441 acattcctaa ttctgaaagt acaaaaccta agacttttga aattgattgt ttagtcggaa
     1501 aaaaacacgc atacgaaata aaatggtggg atgcaactac agatggagac catataacta
     1561 aagaacacac tagaataaaa gttattcata acaaaggata tataccaatt cggttaatgt
     1621 tctactatcc aaatagaact caagctataa aaattcagca aactttagaa acattgtata
     1681 acggtattgg agggaaatat tattatggag attctgcctg ggaacattta agagcagtga
     1741 ccggtattga tttacttagt attctaacag atattgcaaa taaaaaaaca ggggtaaaat
     1801 caaaatgaca gtattaaaag gagataactt agaaatatta aaaactattg aatcctcaag
     1861 tattgattta atctatatgg accctccttt ctttacacag aaaacccaaa aattatctaa
     1921 taacaaaaat attatgtatt cattcgaaga tacgtggact tcgattgagg attacaaaga
     1981 atttttgtct gtaagattag aagaatgcaa aagagtgcta aaaaatagtg gcagcatttt
     2041 cgttcattgt gataaaattg caaatcatca tattagatta attttagata atatctttgg
     2101 atcagatatg tttcaaagcg aaattatatg gaactataaa cggtggtcta attcaaaaaa
     2161 gggattattg aacaatcatc aaaacattta cttttattca aagtcaaaag attttaaatt
     2221 taatacaatt tttacagagt attcttctac tacaaatatc gaccaaatac tagtggaacg
     2281 aaaacgagat ggaaactcta aaactatata taaagttgat aataatggta actatattct
     2341 agcaaaagag aaaaatggag ttcccctttc agatgtttgg aatataccat ttcttaatcc
     2401 aaaagctaaa gaaagagtag gttatcctac acaaaaacct attctgttat tagaacaaat
     2461 tataaagatt gctactgata aaaatgatat agttttagac ccgttctgtg gaagtggaac
     2521 tactttagta gcctccaaga ttttgaatag aaattatatg gggattgatt tatctgagga
     2581 agctatcaat ataactcagc aacgtctgga aaatgttata aaaacaagtt caaatttatt
     2641 gaataaagga atcgaagcat atagaaccaa aactgaggaa gaggaaaaca ttcttaaatt
     2701 attacaggca aaaattgttc aaagaaataa aggaattgat ggttttttac ctaaacattt
     2761 tcaaaaaaaa ccgataccta taaaaattca aaaaaataat gaatgtctga atgagagtat
     2821 ctctttatta cagaatgcta taaactccaa aaaacttgat tttggagtag ttataaaaac
     2881 tcattcagat aatttattat ttgattttga tacgattcct gaaaatataa tagtagttga
     2941 ccattttgaa cttacaatcg aaaaatggtt aagtaaaagt caacagttac tatagtttgc
     3001 aaattattta cagaaagaac aaaaatgctc tgaaacactg atttcaaagc atttttttgt
     3061 tagtttaaaa ttactcccat tcttcttttc caaacgtaca atatatccaa aaccattcaa
     3121 aatactagat tctatttttt ataatatcac taaatccacc taattatagg acgttttcag
     3181 atttttagtc ccgtcccagt cccagtaccg gagaaatatt gttttaatat aatatctctt
     3241 tttgtcttct aagctcttaa aagcaaaaga acaagtaaag agtcaagaca aggataaaaa
     3301 gtccatatta gggcaaataa aaagctttaa gacagatgac aaatctaagt caaataagaa
     3361 agaccatagc aaaggtgcag agagataaat attggcggtc ttcggactgc ctttattttt
     3421 ttatccattt ttcaaatcaa atttattcag actatatatg cacatataca cttaaattca
     3481 tataaaaaca tggcttgtaa aaaattactt taatcacaat aatcgcattt aaaattgtga
     3541 tgtttgcaag ctaaattacg gacttcactt ggaagttttc ccttgtatct tttataatag
     3601 atagaaaatt tgctggcaga tgaatatcca acagattctg ctatctcttt tataggtagt
     3661 tcagtgttta aaagaagagt ttcagctaca ttcattcttt ttctttgagt gtactctgta
     3721 atgctttgac aatatttttc cttaaataaa ttttttaatt tagtaccact cattttagat
     3781 attttttcaa gcgtgccttg atttacattc gttgcaaaat gatcatctaa gaatcttgct
     3841 acatcttcaa gtgctttatc atcatcaatt tcaattttat atttttttct atttaagtat
     3901 gtgtcaatta ctatacttat ccattcattt gcctttgctt taaagaaaaa atcagcggca
     3961 ggagcgtcca tcttacaatt taatatttcc attgccactc tttctaaggc ctttgtaagt
     4021 attatttgat tcggttgaag caaggttgaa taaaaagatt ctggattaat gttaatagat
     4081 gctaaatgtt tttctattag ctctttttta aaaccaatgg aaacagcaag ataacaacaa
     4141 ttctcgtgta ataaaaaaac aaaatcatct tttatattat caaaatcaaa agtacataga
     4201 gagtttgcgg taatagtttg atacggatta aacttttctc cgtttgcact gacaatgtaa
     4261 cttgaataaa ttgaaacata gtctgacata ctataagtgc tattttgaac tacttcctct
     4321 ttgatataaa aatcatgtat atcgataatg aagctgcctc cttcataaaa ccaatatagg
     4381 ccttctgcat aagttgaatt ctcttttttc caacaaaatg tatgacctgc acttgaatac
     4441 ttctcattgt ttttacattc atctactttc atataatctt ttacaaaatc ataatatgac
     4501 ataacacact atccctttta gacaatattc caattagcct tattaattca aaactattgt
     4561 attagtaatt ataacagatg tataatagaa aagcaatgat agatattatc aattaagcga
     4621 atttatatct aaaagggata ttaaagaaag gagatatgct tatgaagatt tacaaaaaac
     4681 tatttgctta tgtccaagat aagaaatatc ttggggtttt ggccataatt ttttctgcta
     4741 tatctgctct acttacagta tatggatatt atttaatcta caaatttcta gataagttaa
     4801 taattaattc aaatttatcc ggtgcagaga gtatagcatt aaaatctgtt attacactaa
     4861 caagtggagc gatattttat tttgtctcag gaatgttttc acatatcttg ggattcaggc
     4921 ttgaaacaaa tttaagaaaa aggggaatcg atggtctgga aaaagcaagt tttaggttct
     4981 ttgacttaaa tccatctggt caaataagaa agatcataga tgataatgca gcacaaactc
     5041 atcaggtggt agcacacatg attcccgata gttctcaggc aataatcaca cccgtacttg
     5101 tacttgcact tggctttata gtaagtataa gagttggcat aattttgctt gctcttacta
     5161 taattggtgg cttaatttta ggggcgatga tgggcgagca agaatttatg aagatatacc
     5221 aagaatccct atctaaacta agtgctgaaa ctgttgagta cgtgagagga atgcaagttg
     5281 taaaaatatt taaagcaaat gtagagtcat ttaaaagctt ttacaaggct ataaaagatt
     5341 actcaaagta tgcttatgat tattccctat cttgtaaaag gccttatgtt ttgtatcaat
     5401 ggttattttt tggactgatt gcaattttaa ttattcctat agtttatttt atgactagct
     5461 tagctagcgc aaaggtgatt ttacttgagc ttatcatgat tttattttta tcaggagttc
     5521 tctttgtttc attcatgaga atgatgtggt actccatgta tatttctcaa ggaaattatg
     5581 cagtagatac tttagaggcg ctttacgaag atatgcaaaa agacaaatta gtgcatggta
     5641 atgtcaataa ttttaaaaac tataatatag aatttgagaa tgttagcttt gcttataatg
     5701 ataaagctgt cattgaaaat ttatccttta atttagaaga aggaaagtcc tacgcacttg
     5761 tcggttcatc tggatcaggc aaatcaacag tagcaaaact tatatcaggt ttttacaatg
     5821 ttaatgaagg aagcataaag ataggcggga tagcaataag tgaatattct gacgaagcct
     5881 taattaaagc catttccttt gtttttcaag attcaaaatt attcaagaag agcatttatg
     5941 ataatgtagc tttagctaat aaagatgcga cgaaagatga cgttatgaga gccttaaaat
     6001 tagcaggatg cgatttaata ttagacaaat tcccagaaag agaaaataca atcataggct
     6061 caaaaggtgt ttatttatcc ggtggagaaa aacaaagaat tgcaattgct agagcaattt
     6121 taaaggattc caaaattatt attatggatg aagcatcagc atctattgac ccagataacg
     6181 agtttgaatt gcaaaaagct tttaaaaatc ttatgaagga taaaacagtt atcatgattg
     6241 cacacaggct atctacaatt aaagaccttg atgaaattat tgtcatggat agtggaaaaa
     6301 ttatagaaag agggtctgac aaagaattaa tgtcaaaaga tacaaggtat aagagcctgc
     6361 aagagatgtt taacagtgcg aatgaatgga gggtttcaaa tgaaagagtt ttataaaaaa
     6421 agatttgctc ttacagatgg aggagcaaga aatttaagta aagcaacact ggcttcattt
     6481 ttcgtttatt gtataaacat gcttcctgcc atattactta tgatttttgc tcaggaagtt
     6541 ttggaaaata tgggcaaaag caatggcttt tatatagtat tctcagtttt gactttgata
     6601 gcaatgtata ttttgctttc tatcgaatac gataaattat ataacacaac ctatcaagaa
     6661 agtgcagatt taagaataag gacagcggag aatttatcaa aattacctct atcttacttt
     6721 tctaaacatg acatttccga catttcacaa acaatcatgg ctgatattga aggcatagag
     6781 catgcaatga gccactcaat accaaaggtg ggcggcatgg tactgttttt cccattaata
     6841 tctgtaatga tgctagcggg caatgtcaag atgggtttag ctgtaattat tccatctatt
     6901 ttaagcttta tatttatacc tttatctaaa aaatatcagg ttaatggaca gaatagatat
     6961 tatgatgtct taagaaaaaa ctcagaaagc tttcaagaaa atatcgaaat gcaaatggag
     7021 attaaagcat ataatttatc gaaggatatt aaagatgact tatataaaaa aatggaagat
     7081 agtgagagag tacacttaaa ggcggaagta actacaattt taactttgtc tatatcttca
     7141 atatttagct ttatatctct tgctgttgtg atatttgtcg gcgtaaatct aattattaat
     7201 aaagagataa attctctcta ccttatagga tatttactag ctgctatgaa gataaaagac
     7261 tctttagatg catctaaaga gggcttgatg gaaatatttt atttatcgcc caaaatagaa
     7321 agattaaaag aaattcaaaa tcaagattta caagaaggcg atgactatag cttaaaaaaa
     7381 tttgatattg atctaaaaga tgttgagttt gcctacaata aagacgcaaa agttttaaat
     7441 ggtgtaagtt ttaaagctaa gcagggagag gtcactgctt tggtaggtgc aagtggctgc
     7501 ggtaaaacaa ctatcttgaa acttatatca agactttatg attatgacaa gggacaaatc
     7561 ttaatcgatg gcaaagatat aaaagaaata tcaacagaat ctctttttga taaggtctct
     7621 atagttttcc aagatgtggt tctctttaat caaagcgtta tggaaaatat tagaatcgga
     7681 aagcaagatg caagtgacga agaggttaaa agagcagcaa aacttgcaaa ttgcacagat
     7741 tttatagaaa aaatggataa aggtttcgat acagttattg gtgagaacgg agctgagcta
     7801 tcaggaggag aaagacaaag attatcaata gccagagcct tcttaaaaga tgcgccgata
     7861 ttgatcttag atgagataac agcaagcctt gatgttaaca acgagaaaaa gattcaagag
     7921 tctttaaata atttagttaa agataaaact gttgtaatca tttcacatag aatgaaatcc
     7981 atagaaaatg cagacaagat agtagttctt caaaacggaa gagtagaaag cgaaggtaag
     8041 catgaagagc ttttacaaaa atcaaaaatt tacaaaaatt taatagaaaa gacaaaaatg
     8101 gcagaagaat ttatttatta ggaggactac aatggataat aaaaaattaa aagtaaaaga
     8161 tttagtaagt atcggtgttt ttggcgtaat ttattttgcc ttcatgtttg gagttggtat
     8221 gatgggcttg attccaatat tgttcttaat atacccgaca gtattagcca tagttgcagg
     8281 aactgttgtt atgttattta tggctaaggt tcaaaagcca tgggcactat ttatatttgg
     8341 tatgatatca ccacttgtga tgtttgcagc tggtcatacc tacatagttg tggttttatc
     8401 acttatagta atgataatag cagaattaat tagaaagatt ggtaattata attcatttaa
     8461 atacaatatg ctttcttatg caatcttcag cacatggata tgtagctctt taatgcaaat
     8521 gcttttagca aaagaaaaat atatggagtg gtctttgatg acgatgggaa aagattatgt
     8581 tgatgtatta gaaaagttaa taacttatcc tcacatggct ttagtagcct taggtgcttt
     8641 cttaggagga attcttggag catatatagg caaggctcta ttgaaaaaac acttttcaaa
     8701 tggattatat tgtgtgggat actttactcc ttgcctaatt ttatggtgtt atctgaatta
     8761 aaccctatag ttaagatgtt tttgagtata cctattgtta ttagaatgtt tattttacca
     8821 tttatggcag caagctttat gataaagacc tcggatgtag gcgcaataat ttcatcgatg
     8881 gataagctta agatttcaaa gaatgtatcc atacctattg cggttatgtt tagattcttc
     8941 ccatctttta aggaggagaa gaaaaacatc aaaatggcta tgagagtaag agggataaat
     9001 tttaaaaacc cagtcaaata tcttgaatat gtttctgtgc cactactcat tatatcatct
     9061 aatatatcag atgacattgc aaaagcggca gaaacaaagg caatagaaaa tccaattgcc
     9121 aagaccagat acattcgcgt aaagatacag ctaattgatt ttgtttatgt tttagcggtt
     9181 gctggactta ttgtgggagg attaatatgg ttgaaataaa aaatttaagt cttgattatg
     9241 gtgaagagca tatattagat gatatatcac tatccatagc cgagggagag tgcgtgctat
     9301 ttacaggaaa aagtggaaat ggtaagtcat ctttaataaa ttcaatcaat ggactagctg
     9361 taaggtatga caacgcaaag acaaagggcg aaataattat tgatggtaag aatataaaaa
     9421 atttggaact ttatcaaatc tcaatgcttg tttcaactgt ttttcaaaat cctaagacat
     9481 atttttttaa tgtcaatacg acattagaat tattatttta tttggaaaat atcggtcttg
     9541 caagagaaga gatggacagg cgtttgaagg atatgcttga gatattcccg ataaaaaatc
     9601 ttttaaacag aaatatattt aatctatccg gcggtgaaaa acaaattctt tgcattgcag
     9661 cttcttatat agcaggtaca aagattatag ttatggatga gccttcatcg aatttagata
     9721 ttaaaagcat aagtgttttg gcaaagatgc taaagatatt aaaagagaaa ggcataagca
     9781 taattgttgc agagcataga atttattatt tgatggacat agttgaccgt gtatttttaa
     9841 tagataaagg aaagcttaaa aaaacttata ctagaagtga atttttaaag ctagataaaa
     9901 atgaattaaa tgctttaagt ttaagagata aagaattaag taaattaaaa gttccttatt
     9961 taaaagaagg tggagagtat cagataaaaa atcttagcta caaatttact gatgatgagt
    10021 gtttaagctt aaaagatatt tcgttcaagc ttgggaaaat ttatggcata ataggatcca
    10081 acggacgagg aaaatcaacg cttttaagat gtttaatagg tcttgagaaa aaatcaaaag
    10141 aagaaattta ttttaaggga gagaagctat ctaaaaaaga aagactcaaa aactcttcac
    10201 ttgttatgca agatgtaaat catcaattat tcacagatga agtattcaac gagcttagat
    10261 taggagtaaa gaattttgat gaagaaaagg cgaaaatcat cttaaaagat ttaggcctgg
    10321 acgaatttat tgaaaggcat ccgatgagtt tatcaggagg gcaaaagcaa aggcttgcaa
    10381 tagcatctgt tatgtgcaag aattctccat ttgtcttttt tgacgaacct tcaagtggta
    10441 tggattattc caatatgata aaaatatctg aactgattaa taagtataaa accatggata
    10501 aaataatttt tattgtttcc catgatatag aatttttaaa tgaagtggca gatgaaattt
    10561 ttgaattgta aaatagagtc tgttaaacat gtctatagaa ctagtaaatt gtctaaaaat
    10621 ttaaaagata ctaacacata ttgatattta ttagaaaatt aacttcagga tttttacagt
    10681 atttataaac tttataatat gtatttatag tattaataat ttccatatct ttagggaaat
    10741 tctttattta cttaccataa ttaaagagat gagagataaa tatcggcagt cttcggactg
    10801 cctttatttt tttacttaat ttaatgcagt aaatcatacg attgaaagga atctgcttta
    10861 tatgctataa ttaggtggtt aatctataca tttagaaagg taaaatatag aattggagaa
    10921 tgatatggga ttttcatata ataaattgta accgcccaat aacgaagtct attgaaaaat
    10981 ctccagacta gagaactcac ggatagttcc taatctggag atttcttatt tgcacttttc
    11041 ttgtacaact ttagtccatg gtaaataagc ctctaaaact tctttgttta cgagagtttc
    11101 ctcgtttgga agacattcta gaagatagga tagatatttc tcactattta gttgatgacg
    11161 tttagctgtt tccaacaaac tcataat
//
LOCUS       DAVHLA010000060        10281 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVHLA010000060 DAVHLA010000000
VERSION     DAVHLA010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10281
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.060"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            635..1018
                     /locus_tag="VVO77_001916"
     CDS             635..1018
                     /locus_tag="VVO77_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEU5693879.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            1070..1759
                     /locus_tag="VVO77_001917"
     CDS             1070..1759
                     /locus_tag="VVO77_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU5693880.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNLF
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVLQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            1801..2034
                     /locus_tag="VVO77_001918"
     CDS             1801..2034
                     /locus_tag="VVO77_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693881.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFLGAGYVVGFWLLILNENQRAN"
     gene            2185..2796
                     /locus_tag="VVO77_001919"
     CDS             2185..2796
                     /locus_tag="VVO77_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU5693882.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGDFFQNESALIIVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFVPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMLYKSWPLLYYL"
     gene            2957..3751
                     /locus_tag="VVO77_001920"
     CDS             2957..3751
                     /locus_tag="VVO77_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEU5693883.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETVPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            3748..4383
                     /gene="trmB"
                     /locus_tag="VVO77_001921"
     CDS             3748..4383
                     /gene="trmB"
                     /locus_tag="VVO77_001921"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEU5693884.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEAGVSNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            4509..4988
                     /gene="rimP"
                     /locus_tag="VVO77_001922"
     CDS             4509..4988
                     /gene="rimP"
                     /locus_tag="VVO77_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEU5693885.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            5032..6168
                     /gene="nusA"
                     /locus_tag="VVO77_001923"
     CDS             5032..6168
                     /gene="nusA"
                     /locus_tag="VVO77_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEU5693886.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            6190..6483
                     /locus_tag="VVO77_001924"
     CDS             6190..6483
                     /locus_tag="VVO77_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEU5693887.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            6476..6775
                     /locus_tag="VVO77_001925"
     CDS             6476..6775
                     /locus_tag="VVO77_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEU5693888.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            6792..9584
                     /gene="infB"
                     /locus_tag="VVO77_001926"
     CDS             6792..9584
                     /gene="infB"
                     /locus_tag="VVO77_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEU5693889.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     VKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            9835..10185
                     /gene="rbfA"
                     /locus_tag="VVO77_001927"
     CDS             9835..10185
                     /gene="rbfA"
                     /locus_tag="VVO77_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEU5693890.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
BASE COUNT         3142 a         1860 c         2335 g         2944 t
ORIGIN      
        1 atgcttactt tttaaatttt ttaacaattc aagatgtttc gatgacaatt caagatttgg
       61 atgaaaaatt ttaaaaaaca atgatatact aaacttgtca aagttgcaac gggtgctgct
      121 acattatgtt aaaaatcgct cttgattgat aagttggatt tgttaggaaa ggagtaaata
      181 attatggata agaaaaagat agtttcgact ataatatgta tagtatttct tgtagtgtca
      241 gtagataatt tttttagaga cttaaccccg ttactgttca ttttaaatat tattggcctg
      301 tcttgctttt cagtgctaac atacattaac ataaaagaga tactcttaaa tataagtaaa
      361 tgatgatttg gttagtccta gaaccaatca acttatgttt atcggcttgg cagattttat
      421 gtttgtcatt tgtttgtata gaggtatttc agaaacagaa ttctatcaac aactaatcgc
      481 ttatataggt gtattctctg cttgtttatc acgcttctgc tcatgtgggg cttgaagtat
      541 tataaaaagt agctttctat ccttttctga caggatattt gagtagaagg ctctattaaa
      601 ttgttagtga aataaatgaa tggaggtatt taatatgaaa tacagattat tttttgttat
      661 tttcttgagt agtgtgttgg atattctttt agggacattt ttacaaatct ctatcgtatc
      721 tattgggtgg cttgttcttt acagtggttt gtttgaagca ggagttttcc ttcttgctaa
      781 taaaggggtg gcggtaaaaa tcaaggaagt agatattcga aatcgcttta aatttatttt
      841 tggaaaaacc ttatggtttc aaattctttt gctcatcttt ttgataatca aactttatct
      901 tggtttggat gcgaggttga ttttattcta tggacatatt ttcattgtct ttaatgcctt
      961 aatgtatcta ttatctagta gtcaggttag ccttaaaaaa aacaaactgt cttcttaatc
     1021 ttacagcagt agagcctgac aaggtgaggt catagtaggg aggatttcta tgaaaaagta
     1081 tcaacttcta ttcaaaataa gtgcagtctt ctcttactta tttttcgtat ttggtctttc
     1141 tcagctgacg cttatcgtcc aaaactattg gcaattttct tctcagatag gcaatttatt
     1201 ctggattcaa aatatcttga gtttactttt tattggagtc atgattgtgg ttcttgttaa
     1261 gacaggccat ggttatctct tccgcattcc aagaaaaaaa tggctttggt attcgatttt
     1321 gacagtatta gtggtagtgt tacagatctc ttttaacgtt cagacagcta aacatgttca
     1381 gtcaactgcg gaaggttggg ctgtattgat tggttatagt gggactaact ttgcagagct
     1441 aggtatttat atagccctgt tctttctggt tccactgatg gaagaattga tttatagagg
     1501 attactgcaa catgctttct ttaagcattc gcgatttggt cttgatttgc ttcttccttc
     1561 tattttattt gctctccctc atttttcaag cctgcctagt ctgttagata tcttcgtctt
     1621 tgcaacagtt ggaatcatct ttgctggttt gacccgctat accaagagca tttatccatc
     1681 ctatgcggtg catgtgatca ataatattgt agcgaccttc ccgtttttgc tcacttttct
     1741 acatagggtc ttggggtaaa aaaacaaaag gcttgctttt cagccataga ggaggtcatc
     1801 atgtataaac acttattttt cctagattcc aaaactttag atcggttgac accctatatt
     1861 ctagtcttgg cttctgacac cattgctttt aatgtttttg tgctaacctt tgtatctgcg
     1921 gtggttttta atttcctaaa ttccatgcta gctttaatgg ctatcttctt aggagctggc
     1981 tatgtggtcg gattttggtt actaatactc aatgaaaatc aaagagcaaa ctaggaaact
     2041 agccgcaggc tgtacttgag tacggcaagg cgacgttgac gtggtttgaa tttgattttc
     2101 gaagagtata aaatggtttg ttttggaaag gctagaacta aaggatgacg tgtaggaagt
     2161 ctgtttgttg aggaggataa ttttatggag ttttttgata aatttcatgc cttgtgtttt
     2221 ggatttttag tactaataat tgtcattaca gttccttata cgattaacca tggggatttt
     2281 tttcaaaatg aatctgcatt gattattgta agtcttcttg taacctcgct gagtgttgct
     2341 tatgctagaa agtttgaaat gatttctttt gggatgttaa gcaagaaaca acttttgctt
     2401 ttcattgcaa tctttcttct aagtgtgctt gagacgctgg tttatattca tttcttcgct
     2461 gtttcttctg gctcaggggt ccaacacttg gcggaagtca gcagaggaat ttccttgtct
     2521 ttgattttga ctacctcagt ttttgtcccc atccaggagg aactcatttt cagaggactt
     2581 cttcaaggtg cggtttttga caattcttgg ttagggcttg tgctaacttc ctctctcttt
     2641 tctttcatgc atggaccttc taatgtccct tcgtttattt tttatctact tgggggcttg
     2701 ttactgggct ttgcttataa aaagagtcaa aacctatggg tttctactct agtacatatg
     2761 ctttacaaaa gttggccact cttatattat ttataaaaat tatgaaaagg taagcagaag
     2821 acggtgctta cctttttcaa gctataatga tacccaagcc aatccagagg cttttctttg
     2881 agaatcgggt tagagtggtt gacgaatagg ccaaaaacta gtagaatagt aaggaaactt
     2941 tatacggagg aaagaaatgg atttgggtga taatgagcta acactgactc ccatacctgg
     3001 gaaaagtggc aaggcttata tgggtagcta tcctgatggg aagcgcatct ttgtaaaaat
     3061 gaacacctct ccaatcctac ctggtctagc tagagaacaa attgctccac aattattatg
     3121 gagtcgtcgt ttggcagatg ggcgtgatat gtgtgctcaa gaatggttga caggcaagat
     3181 attgaccccc tatgatatga atcgtaagca aatcgtcaat attttaaccc gtcttcatcg
     3241 ctcacgtccg ttgatgacac aattgagtcg tttgggctat gccatggaaa cacctgtaga
     3301 tttactacag tcttggcagg aaacggttcc agatgctttg cgtaaaaatc attttatcag
     3361 tgaagtgatg gctgatttac gtcagactat tccaggattt agagaggacc atgcgaccat
     3421 tgtccatgga gatgtacgac atagtaattg gattgagaca gatagtggct tgatttattt
     3481 agtagattgg gattcggttc gcttgaccga tcgcatgttt gatgtggccc atatgctctg
     3541 ccattatatt tcagaacatc agtggaagga atggttgacc tactacggtt acaagtacaa
     3601 tcaaacggta ttaagtaaat tgtattggta tggtcaattg tcttatttga gtcagatttc
     3661 caagtattat atgaaccaag atttagaaaa tgtcaatcgg gagattcatg gtttgcgtca
     3721 tttccgagac aagtatggaa agagaagatg agagttagaa atcgtaaagg ggcaacagaa
     3781 ttactagagg caaatcccca gtatgtggtc ctcaatccct tggaagccaa ggcaaaatgg
     3841 cgggacttgt ttggcaatga taatcccatt catgtggaag ttggaagtgg aaagggtgcc
     3901 tttgtttcag gtatggccaa gcaaaaccct gacatcaact atatcgggat tgatattcaa
     3961 aagtctgttt tgagctacgc tttggacaag gtgcttgaag ctggagtgtc taacatcaag
     4021 ctcttgtggg tagatggttc tgacttgact gactactttg aagacggtga gattgatcgc
     4081 ttgtatctga acttttcaga tccatggccg aaaaaacgcc atgaaaagcg tcgtttgacc
     4141 tacaagacct ttttggatac cttcaaacgt atcttgcctg aaaatggaga aattcatttc
     4201 aagacggata accgtggctt gtttgagtac agtttagtga gcttttctca atatggcatg
     4261 aaactcaatg gtgtctggct agatttgcat gccagtgatt ttgaaggcaa tgtcatgaca
     4321 gaatacgagc aaaaattctc aaacaagggg caagttatct accgagttga ggcagaattt
     4381 taagagatag cctaaaatta ggctgtacaa gtgcttttgc tttacataag ttggcaaacg
     4441 tgctatactg atagtaagaa tatgaaaagt gaggcgggga aatatcttcg cctcttgctt
     4501 atgaggaggt ggacgcaatc gcaacaatcg tagaattagt cagagaagtt gtagaacctg
     4561 tcatagaagc tccttttgaa ctcgtggata tcgagtatgg aaagattggc agtgacatga
     4621 ttctcagtat ttttgtagat aaacccgaag gaattacctt gaacgacacg gcagacttga
     4681 cagaaatgat cagtcctgtc ctagacacca tcaagccaga tcccttccca gaacaatatt
     4741 tcctagaaat taccagtcca ggtttggaac gtcctttgaa aaccaaggat gccgtcgctg
     4801 gagcggttgg aaaatacatc catgtcgggc tctaccaagc catcgataag caaaaggtct
     4861 ttgaaggaac tttgttggcc ttcgaagagg acgagttgac tatggaatat atggacaaga
     4921 cgcgtaagaa aaccgtccaa attccataca gtttagtatc aaaagcacgt ttagcagtta
     4981 aattatagaa aaagaaagga tagcttttga ggattcaaaa gtgaagaaaa catgagtaaa
     5041 gaaatgctag aggccttccg cattttggaa gaagacaagg gaatcaaaaa agaagatatc
     5101 atcgacgcag tagtagagtc gcttcgttcc gcttatcgca gacgctatgg tcagtcagac
     5161 agcgtagcta ttgacttcaa cgaaaaaaca ggtgacttta cagtttatac tgtccgtgaa
     5221 gttgttgatg aagtatttga tagccgtttg gaaatcagct tgaaagatgc tcttgccatt
     5281 aattcagctt atgaacttgg agacaaaatc aagtttgaag aagcaccagc tgagtttggt
     5341 cgtgtagcag cccaatctgc caaacaaacc atcatggaaa aaatgcgcaa gcaaacacgt
     5401 gccatcactt acaatactta caaagaacat gagcaagaaa tcatgtctgg tacagtagaa
     5461 cgctttgaca accgctttat ctatgtcaac cttggtagta tcgaagccca attgtcaaaa
     5521 caagaccaaa ttcctggaga agtttttgct tctcatgatc gtatcgaagt ttatgtttac
     5581 aaggttgaag acaaccctcg tggtgtgaac gtctttgtta gccgtagcca tccagaaatg
     5641 atcaaacgtt tgatggagca agaaattcca gaagtttatg atggaactgt tgaaatcatg
     5701 agcgtggctc gtgaagcagg tgaccgtacg aaggttgctg ttcgtagcca caatccaaac
     5761 gtggatgcta tcggtacaat cgttggacgt ggtggtgcta atatcaagaa gattactagc
     5821 aaattccacc cagctcgtta cgatgctaaa aatgaccgca tggtaccaat cgaagaaaat
     5881 atcgatgtta tcgagtgggt agcagatcca gctgaattta tctacaatgc catcgctcct
     5941 gctgaggttg accaagttat ctttgatgaa aacgacagca aacgtgcctt ggtggttgtt
     6001 ccagataaca agctttctct tgccattggt cgtcgtggac aaaacgtgcg cttggcggct
     6061 cacttgactg gttaccgtat cgatatcaag tctgctagcg aatttgaagc catggaagac
     6121 gctgcttcag tagagttgga agtagaaaac gatactgtag aagaataaaa gctgctagag
     6181 gagggaaaga tgaaaacaag aaaaatccct ttgcgcaagt ctgttgtgtc taacgaagtg
     6241 attgataagc gtgatttgct ccgcattgtc aagaacaagg aaggacaagt ctttattgat
     6301 cctacgggca aggccaatgg ccgcggcgct tatatcaaac tagacaatgc agaagcccta
     6361 gaggcgaaaa agaagaaggt ctttaaccgc agctttagca tggaagtgga agaaagcttt
     6421 tatgacgagt tgatcgctta tgtggatcac aaagtgaaaa gaagagagtt gggacttgaa
     6481 taagcaaaag ataagtaatc tcttggggct tgctcagcga gcagggcgca tcatatcggg
     6541 tgaagaattg gtggtcaagg ccattcaaga cggcaaggcc aagttggtct ttctagctca
     6601 tgatgctgga cccaatctga ccaagaagat tcaagataaa agtcattatt atcaagtaga
     6661 aattgtaacc gtgttttcaa cactggaatt aagcatagca gtcgggaaat cgagaaaggt
     6721 tttggctgta acagatgctg gatttacaaa gaaaatgagg tctcttatgg aatagaagag
     6781 gaggacatga tttgtctaag aaaagattgt acgaaatcgc aaaagaactt ggaaaagaaa
     6841 gtaaagaagt tgtagcgcgt gcaaaagagt taggcttgga tgtgaaaagc cactcatcaa
     6901 gtgtggaaga agctgtcgct gcaaaaattg ctgccagctt taagcctgca gctgctccga
     6961 aagtagaagc aaaacctgca gcaccaaaag taagtgcaga aaagaaagcc gaaaaatctg
     7021 agccagctaa accagctgta gctaaggaag aggcaaaacc ggctgagcca gttgctccga
     7081 aaacagaaaa agtagcagtg aaaccgcaaa gtcgtaattt caaggctgag cgtgaagccc
     7141 gtgctaaaga gcaggcagaa cgacgcaagc aaaataaggg caataaccgt gaccaacaac
     7201 aaaacggaaa ccgtcagaaa aacgacggcc gtaatggtgg aaaacaaggt caaagcaacc
     7261 gcgacaatcg tcgctttaat gaccaagcta agaagcagca aggtcagcaa aaacgtagaa
     7321 atgagcgccg tcagcaagag gataaacgtt caaatcaagc ggctccacgt attgacttta
     7381 aagcccgtgc agcagcccta aaagcagagc aaaatgcaga gtacgctcgt tcaagtgagg
     7441 aacgcttcaa gcagtatcag gctgctaaag aagccttggc tcaagctaac aaacgcaagg
     7501 aaccagagga aatctttgaa gaagcggcta agttagctga acaagcacag caagttcaag
     7561 cagtggttga agtcgtccct gagaaaaaag aacctgcagt ggatacacgt cgtaaaaaac
     7621 aagctcgacc agacaaaaat cgtgacgatt atgatcatga agaagatggt cctagaaaac
     7681 aacaaaagaa tcgaagtagt caaaatcaag tgagaaatca aaagaatagt aactggaata
     7741 acaacaaaaa gaacaaaaaa ggcaataaca agaacaaccg taatcagact ccaaaacctg
     7801 ttacggagcg taaattccat gaattgccaa cagaatttga atatacagat ggtatgaccg
     7861 ttgcggaaat cgcaaaacgt atcaaacgtg aaccagctga aatcgttaag aaacttttca
     7921 tgatgggtgt catggccaca caaaaccaat ccttggatgg ggaaacaatt gaactcctca
     7981 tggtggatta cggtatcgaa gccaaacaaa aggttgaagt ggataatgct gacatcgaac
     8041 gtttctttgt cgaagatggt tatctcaatg aagatgaatt ggttgagcgt ccaccagttg
     8101 ttactatcat gggacacgtt gaccacggta aaacaaccct tttggatact cttcgtaact
     8161 cacgtgttgc gacaggtgaa gcaggtggta ttactcagca tatcggtgcc taccaaatcg
     8221 tggaaaatgg taagaagatt accttccttg atacaccagg acacgcggcc tttacatcaa
     8281 tgcgtgcgcg tggtgcttct gttaccgata ttacgatctt ggtcgtagcg gcagatgacg
     8341 gggttatgcc tcagactatt gaagccatca accactcaaa agcagctaac gttccaatca
     8401 tcgtagctat taacaagatt gataaaccag gtgctaaccc agaacgcgtt atcggtgaat
     8461 tggcagagca tggtgtgatg tcaaccgctt ggggtggaga ttctgaattt gttgaaatct
     8521 cggctaaatt caaccaaaat atcgaagaat tgttggaaac agtccttctt gtggctgaaa
     8581 tccaagaact caaagcagac ccaacagttc gtgcgatcgg tacggttatc gaagcgcgct
     8641 tggataaagg aaaaggtgcg gtcgcaaccc ttcttgtaca acaaggtacc ttgaatgttc
     8701 aagacccaat cgttgtcgga aataccttcg gtcgtgtccg tgctatgacc aacgaccttg
     8761 gtcgtcgtgt taaagttgct ggaccatcaa caccagtctc tatcacaggt ttgaacgaag
     8821 caccgatggc gggtgaccac tttgccgttt acgaggatga aaaatctgcg cgtgcagcag
     8881 gtgaagagcg tgccaaacgt gccctcatga aacaacgtca agctacccaa cgtgttagcc
     8941 ttgaaaacct ctttgatacc cttaaagctg gggaactcaa atctgttaat gttatcatca
     9001 aggccgatgt acaaggttct gttgaagccc tttctgcctc acttcaaaag attgacgtgg
     9061 aaggtgtcaa agtgactatc gtccactcag cggtcggtgc tatcaacgaa tcagatgtga
     9121 cccttgccga agcttcaaat gcctttatcg ttggtttcaa cgtacgccct acaccacaag
     9181 ctcgtcaaca agcagaagct gacgatgtgg aaatccgtct tcacagcatt atctacaagg
     9241 ttatcgaaga gatggaagaa gctatgaaag ggatgcttga tccagaattt gaagaaaaag
     9301 ttattggtga agcggttatc cgtgaaacct tcaaggtgtc taaagtggga actatcggtg
     9361 gatttatggt tatcaacggt aaggttgccc gtgactctaa agtccgtgtt atccgtgatg
     9421 gtgtcgttat ctatgatggt gaactcgcaa gcttgaaaca ctataaagac gacgttaagg
     9481 aagttacaaa cggccgtgaa ggtggattga tgatcgacgg ctacaatgat attaagatgg
     9541 atgatgtgat tgaggcgtat gtcatggaag aaatcaagag ataagatttt ttgctccttt
     9601 cttaggtggt gagggacgca agcaaaccga tggtttcatt gcttattttt gagcctaggg
     9661 tctcaaaaat accctgtgat gggactgata aatcagttcc atcactttca ccacggcgaa
     9721 agaagcagat gacttcaaat tgaacttcgt ttcaatttaa actgaaaatc aagaagttta
     9781 aaatagctag gtctgctggc ctagcttttg gttcaaagta gagaaaggaa tatcatggca
     9841 aatcatttcc gtacagatcg tgtgggcatg gaaatcaagc gtgaagtcaa tgagattttg
     9901 caaaagaaag tccgtgatcc acgtgtccaa ggtgtgacca tcacagatgt tcagatgctg
     9961 ggtgacttgt ctgttgccaa ggtttattac accattttga gtaaccttgc ttcggataac
    10021 caaaaagccc aaatcgggct tgaaaaagca actggtacca tcaaacgtga acttggtcgc
    10081 aatttgaaat tgtacaaaat cccagatttg accttcgtca aagacgagtc catcgagtat
    10141 ggaaacaaga ttgacgagat gctacgcaat ctggataaga actaaagaag aggggttgcc
    10201 cctctttttt ggtggaggaa aataggttga atttgaaatg gaaaaatatt cttttataat
    10261 agattgaaac tagaatagta c
//
LOCUS       DAVHLA010000061        10150 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVHLA010000061 DAVHLA010000000
VERSION     DAVHLA010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10150)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10150)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10150
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.061"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(163..1926)
                     /locus_tag="VVO77_001928"
     CDS             complement(163..1926)
                     /locus_tag="VVO77_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEU5693891.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDRYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
     gene            complement(1935..2525)
                     /locus_tag="VVO77_001929"
     CDS             complement(1935..2525)
                     /locus_tag="VVO77_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEU5693892.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            complement(2623..3114)
                     /gene="rocS"
                     /locus_tag="VVO77_001930"
     CDS             complement(2623..3114)
                     /gene="rocS"
                     /locus_tag="VVO77_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEU5693893.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            complement(3191..3883)
                     /locus_tag="VVO77_001931"
     CDS             complement(3191..3883)
                     /locus_tag="VVO77_001931"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEU5693894.1"
                     /translation="MKIGIIAAMPEELAHLVQHLDNAQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLAFLKALD"
     gene            complement(3900..4214)
                     /locus_tag="VVO77_001932"
     CDS             complement(3900..4214)
                     /locus_tag="VVO77_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEU5693895.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            complement(4226..4771)
                     /locus_tag="VVO77_001933"
     CDS             complement(4226..4771)
                     /locus_tag="VVO77_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU5693896.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            complement(4781..6160)
                     /gene="glmU"
                     /locus_tag="VVO77_001934"
     CDS             complement(4781..6160)
                     /gene="glmU"
                     /locus_tag="VVO77_001934"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEU5693897.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRCRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPRNQ"
     gene            6294..7094
                     /locus_tag="VVO77_001935"
     CDS             6294..7094
                     /locus_tag="VVO77_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEU5693898.1"
                     /translation="MRKQIHPLILFSFLGIMMFILIINRPLNDNQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSIWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            7189..8031
                     /locus_tag="VVO77_001936"
     CDS             7189..8031
                     /locus_tag="VVO77_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEU5693899.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYSLNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNTGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            8031..8513
                     /locus_tag="VVO77_001937"
     CDS             8031..8513
                     /locus_tag="VVO77_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEU5693900.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            8513..9133
                     /locus_tag="VVO77_001938"
     CDS             8513..9133
                     /locus_tag="VVO77_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU5693901.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPADRILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(9386..9481)
                     /locus_tag="VVO77_001939"
                     /pseudo
     CDS             complement(9386..9481)
                     /locus_tag="VVO77_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            9894..10150
                     /locus_tag="VVO77_001940"
                     /pseudo
     CDS             9894..10150
                     /locus_tag="VVO77_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3121 a         2144 c         1769 g         3116 t
ORIGIN      
        1 tataagttat agtgtagcat tccaacttca aagcactata aagtaaattg aaacaagaac
       61 aatacaaaca attctcgtaa acggattgca accacaaaaa agcaagcatt cacaagaata
      121 cttacctatc atgggaggaa caaccgttcc tcttttttat tactaaaatt caaagaattc
      181 caatgctttt ttcaagagca aatccgtata ttctggatct tcttgggcta cttctatttc
      241 ccgctgaact ttttccaaat catctgtaat cactccatct actcctaagt gaagagattt
      301 gctgatagct tctgaatcat tgacagtcca gacataaagt ttctgatccg ttgtccatag
      361 tttgcttaca aaatattcat ccaaggttga gtactccata gtatatcctg tcgctcttgt
      421 tttaggaaag acagaattgt agggcatgat gaaataaact ggcagttcgg catcatactg
      481 tcttactttt tcgacaacat ggtagtctaa agactggatt tgatgtccat aaatcttgag
      541 ctttgcagca taacgggcta aaaagcggtt catcatgtct ggactatctt ttttactggt
      601 tttaatttca attagtaatt tttgaccaag ttcgttggct cgactgagat aatcttcaaa
      661 gcttgaaatt ttagtctggt agccattttc aaaaatatca atccctttaa gctcctccaa
      721 gtttaagtct tgaggacttt tattgatacc tgctagattt ttcaagttag catcatgcat
      781 catgacaaac tgcccatctt ttgtttcctg cacgtccgtc tccaccaagt ctggtttgag
      841 ttgtgctgta gtttccaagg actctactgt attttgaatc ccatttgcat tggaaacccc
      901 tcggtgagaa ataagttgag gtagatgaac catgggagcc tccagataaa tataaccttc
      961 taaggcaaag aaaagactgg cacaagtcat gacaccccat cgcacgatgt gatctttttc
     1021 tctcctagga agcatatcca gctcctttcc tgtcaaaaat gaaacaaatt taaccaaaaa
     1081 ataagtcaga gccatataat agagattttt aatcacgaca aaattcaaaa taccaagaat
     1141 cagagactct ctctgagtga tatcatctac caaagtttga gccaataata aagggatcaa
     1201 aggaagataa aataataaat gtgctttgag caagatgtaa aataaattcc aagcataaaa
     1261 agtaactctc ttcttggttt tctccaagct aaacatcact gcttctcgaa cagtcagctg
     1321 atcatataca atcttcggaa gggcaaacat caatctgaca gagacataga gaaagataag
     1381 agatagaagt aggatgctca gccaccacat ccaatatcta tcttctaaat aagcttggat
     1441 aaactctgga atgacgattt tattaagata ataaatcttc agcattttcc gtataaaagg
     1501 aaacagcata gctatataga aaaagataaa caaggcttta gcgcaagtta gctttttcat
     1561 aaatccaaaa ctttcatgga aaaccttgcg gatatactca attagccttc gcttttcatt
     1621 atagaggaga tgacgagcac caataaagag gagtcctatt tgaaaataag caaccagaag
     1681 gttaattaca atcaaggcta aaaaagctag actaatcaat ggagaatgag taaggatggc
     1741 taagacattg ttataggaaa taaaaagata acctgtctga tctaataaga agctagccaa
     1801 ccatgaattg aatggtaccc acaaatactc cactatcata aaaatcaaga aaaatagaaa
     1861 gaggatttta tcaagattga ggtaaatctg tttaagaccc aattttttag gtttttcagg
     1921 tttcataggc actcctagtc aaataattga gacaagtcca agccaccaaa aggattgttt
     1981 gataagctac tttctgtctc taacaattcc ctagcttgat ccgactctaa gaaggattcg
     2041 taaacacgcg ccgtcatccg agcatcctct aaactattat gagactgacc ttgaaatcca
     2101 agaaatgagg caacagtttg caatttgaga ttggcaatac catgtaaatc tgaactccga
     2161 cgttcaaaag cttcatcata caaatccacc ttgtactgtt ggctatagtc taaaccatgc
     2221 tctgctaaaa taggtaaatc acttttagca gcattgtagc ctatcatcag caaagaaccc
     2281 acaaactctt ggaattcttc taagactttc tcaactggag gagcatcttt taaggtctca
     2341 gctgtaatcc cggtcaaacc attgataaag ctttttagag ggacgctggt atgaacatag
     2401 gaatcatagg catcgatttc ccgaccatct ctaaaacgca ctgccgatac ttgaatcaag
     2461 tgtgtttgtc cttcgtgctg attaaattct aagtcaaaag caatgtaatc ttctaatcgt
     2521 tccattctgt acctctcctc tactgtctct gttctaatca actatactat tcacaaacaa
     2581 aagaagccat caggttagca tttaacctaa acagctcctt gattatcctc caaataaacg
     2641 agcaaaaaag ccttttttag tggattggac ttcttctttt gcttggtcca gctctagctt
     2701 aagattttct tgatccttca tggcttgaag ggtcaattgt tgttgctgat ctaattgttt
     2761 gtctttctca gcaatctgac ggtctttgat acgcatctgc tcgtcttttt ctgataactg
     2821 acgatccttg gcttttaatt gttcataaag acgaagaatt tctgcattct tctcatccac
     2881 tagaatctcc atcagttcac gttgtttgac atcttcactg acaggttcat cttcaaaaat
     2941 cgttttttta tagatttctt ctagcttaat caagccactt ctggtaacaa ctgttacccc
     3001 tttgtcattt ttatctgtgt cttcttctgg taattctttg acacggttat tgattgcttg
     3061 gcgagataat cctaagacct ctgcaatctc actgacggtc atttcaatac tcataatatc
     3121 ctctgaaacg ttttctagct tttctttact taaatcttat cataagctag aaaaactgtc
     3181 aaatttccgc ttaatctaaa gccttcaaaa aggccaacaa gacttgggca gagcgacgtc
     3241 cagcttcgat aataaactca tcaaaaaaga tgtttgcttc atggttggca ttgtcactca
     3301 tagctctgat gactaagact gggagattga gggcatgcgc tgcttgagca atagctgccc
     3361 cctccatctc cacggctaaa acttctggga aatgggactt aatcgcttct atcttgtcat
     3421 ttcctgcaac aaaactatct cctgtagcaa tcaaaccaag atgccagttt tggtccaatt
     3481 gagataaact ctcttggatt tgagcaacaa aggttttgtc tgattcgaaa taaagcggtt
     3541 gttgcgccat ttgtccataa gcatagccaa aagctgtgac atccacgtca tgataggcta
     3601 atttgtcagc aatcacgaca tccccaacag cgataccttc tgctactgcc ccagctgaac
     3661 ccgtattaat aagggcatcc acctggaaat gatcagccaa aatcgccaca ctcatagcag
     3721 acatgacctt accaattcca ctttctacaa gaacgacttc atgagaagca atggttcctg
     3781 tatgataggt attccccaaa acaacttgct cctgggcatt gtctaaatgc tggaccagat
     3841 gagccagttc ttctggcata gcagcaataa ttcctatttt catttcaatt ccttttctat
     3901 tacaaaagtt tcattgctaa aacaagcaaa atcaagagaa agatgaccgc gaataagatt
     3961 ttattcaact tagaattgaa gacatttctc ttggtatttt caatgcgacg gcttttatga
     4021 atagatggtt cgacctgaat cttcaaggtt tcctggctaa aaccatgatc cttaggattg
     4081 gcataaccaa aacgggaaga agaggttggt aaaatcttag tttcctcatt atcatccagc
     4141 aaaggaggac ctgaaatttt ttcgcctcta ttagctcttt caatcatttc atccgttaat
     4201 aaagatttac ccatactgac ctcctctatt ttttctgcaa ctcccaatac tgaacagcca
     4261 taattgtctt ggcatcacag atatgacctg attggattaa ttctttcgct tcttctaagc
     4321 tcacttcaag gacttccaag gtttcatcct catcctgcgg acgcggattt tccacttttg
     4381 tcaaatcgct tgctaaatat agttttaact tctcattaca aaagccaata gctgaataaa
     4441 aatcgtacaa gagttctaat ttccctgtat aggctgtttc ttcctctaat tcacgaaggg
     4501 cagctgccac aggggctgtg ttttctccta cctccaattt tccggctgga atttcgtaag
     4561 agacagcctc gatagctttg cggtactgct tgaccaagat aagtttttgt tcatccgtta
     4621 ctgctaaaac acagacagcc ccattgtgga aaatcaaatc ccgttgggca gttcccttgc
     4681 cttctggtaa ttcaacctga tcttggacca gtttaaatat tggtccttga tagatttctt
     4741 ttcggctaag cgttttttct tcaaactcca tgataggctc ctactggttc ctaggatgat
     4801 gaggaagacg tgttgcatat tcgtctttat tgatctgacg accgcgacca atagcaatag
     4861 catctgctgg cacgtcttta gtaatagttg aaccagcacc aacgagggaa ttgtcaccaa
     4921 gttctactgg tgcaataatg gttgaatttg aaccaacaaa gacattgtct ccaatgactg
     4981 tcttgtattt gtttttgccg tcatagttga ctgtaatagt tccagcaccg aaattaacgt
     5041 tgcttcccac ttcacagttt ccgatataag tcaaatgacc agccttggta ttctcaccga
     5101 ttgaagatcc tttcacctca acaaagttac caatatgaac ttgggcaccc agacttgaat
     5161 ttggacgaat gtgagcataa ggaccgactg tcacaccgtc tgcaacacta ctttcctcaa
     5221 tcatagaatt ggtaatgacc gctcctgctc cgatagtgct gtccactaca taagtaccgt
     5281 ttgtcaaaac agtctcagca ccaattttcg tttgcccttt caaggtaaca ttggcttcga
     5341 tttgaacttc cggagcaatc tcaacatcaa tatcgatata agttgcttct ggattgacaa
     5401 agctaacacc attgaccatg tgtttatgat tgatgcgaca acgcataact gactcagctg
     5461 tcgcaagcgc cacacggtca tttaccccaa gactttcatc aaaatctttc aaagtataag
     5521 cgccaacttt ttcaccagtt tcacggaaaa taccaatgac gtctgtaata tagtattcgc
     5581 cttgagcgtt attggtattg atatttttca aagcctcaaa caaacgctcg ttgtcaaaga
     5641 cgtatgttcc agtgttgatt tccttgattt gcttttcaaa atctgtagca tccttctgct
     5701 caacaatacg aagaacctca gcattgtcat tacgaacaat tcgtccatag ccaaaaggat
     5761 tatccgtttc agcagtcaag atagtggcca catttttatg attgatatgg aaatcaatca
     5821 agtttttcaa gctttcacca gtgattaaag gagtatctcc tgcaatgacc aaggtgtgtc
     5881 ctgacaaacc ttctaagata ggctctgtca tcataactgc atgaccagtt cccaactgtt
     5941 cagattgagt cacaaattct gtctgtccag ccaagacctc ctcaaccaat tctgccttgt
     6001 gtcctacaac tgttactgtc ttttcaggtt ggatagctcc cacactacgg aaaacatgtt
     6061 ccaacataga aatacccgca accttgtgca aaacttttgg caaatcagat ttcatgcgag
     6121 tccctttacc cgctgctaaa ataatggcaa aatttgacat aatcttctct tttctgtaga
     6181 aattcccttt tattatacca tatttcaaat cattccgcac tcttgaatga aaaaatgctc
     6241 taaagtctct tccttaaccc atttttttga tttttagggt agaattataa gatatgagaa
     6301 aacaaattca tccacttatt ttatttagtt ttttggggat tatgatgttc attttaatca
     6361 tcaatcgccc acttaatgac aaccaatcgt ttaaaacaaa atccaatata gcacagattg
     6421 aagcacaggc tttgaaacac ttagacaaac cgattattga cctctctggc tggcagcgtc
     6481 ctgaggaaat caactacgat gccctctcac aaaatatttc aggtgctatt gttcgtgttc
     6541 acagtggtgc tcaaacgaca aaagaaaatg atgcttcatt tatcaatgga atagacaagg
     6601 cctataagag tcatatcact gaacttcaaa agcggaatgt cccagttgct gtctacgctt
     6661 atgtagctgg aaaaagtgtc caagaaatgg aaaaggctgc cgaagttttc tacaatgctg
     6721 cctctcctta cagccctagt tactattggc ttgacgtgga agacaaaacc atgtctaata
     6781 tgaacgaagg tgtcgaaaac tttcgagcaa aactagcatc actaggtgct aaaaacatcg
     6841 gcatctacgt tggtgtctac ttcatggaag aacacagtat tgatacaggc aagtttacct
     6901 ctatttggat tccgtcctac ggctcagact caggattttt ggagagcagt cctaaaactg
     6961 atttagatta tgatattcac caatacacat ctaaaggaaa aattgccggc tttgaccacg
     7021 atttagatat caacgttatc tctcccttaa aaaataaaga agaaaccttt cgaaaacttt
     7081 ttttaaaacc ttaaaagcat ttgtttatca tttgcttttt ctttttgtgt ctgattgtga
     7141 tacaatatag taaggatttt ttgaaataga aatagttgga ggaaatatat gctctcatgg
     7201 ttagcacgcg ttattaaagg aattgtgatt gctcttggat ttatcctacc gggaatttcc
     7261 ggaggggttc tagcagcaat cttaggaatc tatgaacgaa tgattggctt tctggctcat
     7321 ccctttaaag accttaaaga aaatgttttg tactttattc cagttgccat cggtatgctt
     7381 ctgggaatcg gcttattttc ctacccgatt gaatacctgc ttgaaaatta tcaggtcttt
     7441 gtattatgga gctttgcggg agctattatc ggtacagttc ctagcctcct caaagaatca
     7501 actcgagaat ctgaccgaga caagattgat ttagcttggt tatggacaac ctttatcatt
     7561 tctggattag gactctattc cttaaatttt gtcgttggaa ccttaagcgc cagctttctt
     7621 aacttcgtcc tagcaggcgc actattggcc cttggcgtct tggttcctgg cctcagccca
     7681 tcgaatttac ttttgatttt gggactctat gctcctatgt tgactggttt taaaactttt
     7741 gatctcttgg gaaccttctt tccgattgga attggtgcag gtgcaactct catcgttttt
     7801 tcaaaattga tggattatgc cttaaacaac taccactcac gcgtctatca tttcatcatc
     7861 ggtatcgtcc tatcaagtac ccttttgatc ttaattccaa atacaggaaa cgctgaaagt
     7921 atccaataca caggactttc acttgtcggt tatgtcatca tcgccttctt ctttgcgctg
     7981 ggaatctggc ttggtatttg gatgagtcaa ttggaggata aatataaata atggcaaaaa
     8041 aagttaaaat caaaaaaaca ttggtggaac aaatcctatc taaagcagct atccctcatc
     8101 aggggattca aatcaatgcc ctagaaggag agcttcctca aggttatgaa cgagatcaga
     8161 ttttcaaaac cttggcgctt ttgggagaca agaccggacc gattatcgga attgtcccta
     8221 tcactcagca cttgtctgaa aagaaactag ctaaaatttc tggcaataaa aaagtgagca
     8281 tgattccaca aaaggactta gaaaaaacaa ctggttacat tcatggagcc aataatcctg
     8341 tcggaattcg tcagaaacac aattatccca tttttatcga taaaattgct ctagatttgg
     8401 atcgaatgat tgtctctgca ggcgaagtcg gacacagcat tatcgtcgcg ccacaagact
     8461 tggctagctt tgtaaaggca gactttgtag atattttgga ggacatcaag taatgaaact
     8521 ctactttgtc cgccacggtc gtaccctctg gaaccaagaa ggtcgttttc aaggtgctag
     8581 cggtgattct cctcttcttc ctgaatccat tgaaacccta aaacgacttg gccagtatct
     8641 caaggaaatt ccttttgatc agatttattc aagtgattta cctcgagcgg tcaaatctgc
     8701 tgagattatc caaagtcaac tccatacccc ctgttcttta gaaatcgttc ctaatctccg
     8761 tgaatggcaa cttgggaagt tagaaggttt gaaaattgca accttggaag ctatttaccc
     8821 gcaacaaatc caggcttttc gttcaaatct tgctcaattt gacactcgaa tgttcggagc
     8881 cgaatccctc tatagtacaa ctcagcggac catccaattt atcaaatcat taaaagatag
     8941 tccagctgat cgtattctaa ttgtcggaca cggcgccaat cttactgcca gtcttcgtac
     9001 tctcctaggc tataaagaac cacttcttcg taaagatggc ggtctagcaa atgccagcct
     9061 gaccattata gaaacccatg attttgaaac attcactctc aatacttgga atgatacttc
     9121 ttatcaatca taattatagc ctagccttct gaactagaac cataggagat atagtcagtt
     9181 gaaacaaaaa taagacaaaa gaaccttgta aaaaggtatt gcaacttgcc aatacctttt
     9241 tgatatgaac acgtgtcttc tcaacaggat tgtagagcaa aatgaaataa gaactgaata
     9301 atatgatttg agaatttaaa tcaatttata agaatgtttt agaagcagtt atgtactatt
     9361 ttagattcac ttttctatac taagatgagt agggaggaaa aggtaaaagt ttatgcccaa
     9421 attcttcaca taagaactct agcttaccca ttctatggaa tcttgcatta tccattaaaa
     9481 cttccagact catacccttc taaaatctat tcaaaccacg tcagcttcac attatatatg
     9541 ttggtgacct cacaagtttt atctacaacc tcaaagctgt tctttgagca gcctacagct
     9601 agcttcctag tttaatcttt gcttttcact gagtatcaag ttaaaaaaat gaggctggtc
     9661 aaaaagtctt taaaataaaa aacgcatatt atcaggtgtt aaatgaactg caccccaaaa
     9721 gttagacaga aaaaatctaa cttttggggt gtttttatta tgaaattaac ttatgatgat
     9781 aaagttcaga tctatgaact tagaaaacaa ggatatagct tagagaagct ttcaaataaa
     9841 tttgagataa acaattctaa tattaggtac atgattaaat tgattgatcg ttaatgttgg
     9901 aacaggcatt caaagagaag cactacgaga atacgattct ccatagtgac caaggctggc
     9961 aatatcaaca cgattcttat catcggttcc tagagagtaa gggaattcaa gcatctatgt
    10021 cacgcaaggg aaacagccaa gacaacggta tgatggaatc tttctttggc attttaaaat
    10081 ccgaaatgtt ttatggctat gagaaaacat ttaaatcact taatcaattg gaacaagcca
    10141 ttatagacta
//
LOCUS       DAVHLA010000062         9812 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVHLA010000062 DAVHLA010000000
VERSION     DAVHLA010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9812)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9812)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9812
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.062"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            346..6780
                     /locus_tag="VVO77_001941"
     CDS             346..6780
                     /locus_tag="VVO77_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEU5693902.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALSISDKEKV
                     VVDKETENKEKHKDIHNAIETSKDTEEKKTTIIEEKEVVSKNPVIDTKTSNEEAKIKE
                     ENSNQSQGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGEKAIKGLSNLKNTKVLYT
                     YDRIFNGSAIETTPDNLDKIKQIEGISSIERAQKVQPMMNHARKEIGVEEAIDYLKSI
                     NAPFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDK
                     IPHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNA
                     QIFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRA
                     LRKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQ
                     TVEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLD
                     LRGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEG
                     TKSQVFSISGDDGVKLWNMINPDKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNV
                     GDEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVI
                     NGKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIAL
                     QNTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYG
                     SISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDG
                     KQIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFES
                     VEEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDG
                     KPKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSS
                     GSKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVI
                     SREHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPAT
                     KIRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLI
                     TKDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTY
                     AGEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFADQADEK
                     GMISYYLVDPDKDASKYEKLGEISEDKLKNAKSPEENTNNNQAKDEDSKPDEKSSVEG
                     EASLEINKTISTIREFENKDLKKLIKKKFREVDDFTSETGKRIEEYDYKYDDKRNIIA
                     YDDGSALQYETEKFDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNSYKSIE
                     IKATKYDSHSKTMIFDLYANINDIVDGLAFAGDMRLFVKDDNQIKAETKIRMPEKNKE
                     TKAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKG
                     YALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRST
                     QAVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDK
                     SNVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNW
                     ELRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMD
                     GNVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKR
                     NNGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDT
                     GEVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKK
                     DAGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDL
                     QREDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIV
                     GIFLGLKKKNQD"
     gene            7405..7881
                     /locus_tag="VVO77_001942"
     CDS             7405..7881
                     /locus_tag="VVO77_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU5693903.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAETTA"
     gene            7919..8224
                     /locus_tag="VVO77_001943"
     CDS             7919..8224
                     /locus_tag="VVO77_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU5693904.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            8272..9747
                     /locus_tag="VVO77_001944"
     CDS             8272..9747
                     /locus_tag="VVO77_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEU5693905.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
BASE COUNT         3623 a         1476 c         1889 g         2824 t
ORIGIN      
        1 atctacaacc tcaaaacagt gttttgagct gactacgtca gttccatcta caacctcaaa
       61 acagtgtttt gagcaacctg cggctagttt cctagtttgc tctttgattt tcattgagta
      121 ctaatcttat tttttaacgt gtgctaaaaa ataaattaat gcatgttaat ttttttgact
      181 taaatttttt taaatgatat actgttttta tagagagata acaattatat ataaatgtac
      241 tactctattt cctagataat acttagtaaa actttttata acaaaggcta gcaaagttaa
      301 agtttattat ctattggaag ttaaataaat atgtaaggaa ttaaaatgaa aaaaagcaca
      361 gtattgtcat taactacagc tgcagttatt ttagcagcct atgcccctaa tgaggtagtc
      421 ttagcagaca catctagctc tgaagatgct ttaagcatct ctgataaaga aaaagtagta
      481 gtagataagg aaacagaaaa taaagagaaa cataaagata ttcataatgc tatagaaact
      541 tcaaaggata ctgaagaaaa gaaaacaaca attattgagg aaaaagaagt tgttagtaaa
      601 aatcctgtaa tagacactaa aactagcaat gaagaagcaa aaatcaaaga agaaaattcc
      661 aatcaatccc aaggagatca tacggactca tttgtgaata aaaacacaga aaatcccaaa
      721 aaagaagata aagttgtcta tattgctgaa tttaaagata aagaatctgg agaaaaagca
      781 atcaagggac tatcaaatct taagaataca aaagttttat atacttatga tagaattttt
      841 aacggtagtg ccatagaaac aactccagat aacttggaca aaattaaaca aatagaaggt
      901 atttcatcga ttgaaagggc acaaaaagtc caacccatga tgaatcatgc cagaaaggaa
      961 attggagttg aggaagctat tgattaccta aagtctatca atgctccgtt tgggaaaaat
     1021 tttgatggta gaggtatggt catttcaaat atcgatactg gaacagatta tagacataag
     1081 gctatgagaa tcgatgatga tgccaaagcc tcaatgagat ttaaaaaaga agacttaaaa
     1141 ggaactgata aaaattattg gttgagtgat aaaatccctc atgcgttcaa ttattataat
     1201 ggtggcaaaa tcactgtaga aaaatatgat gatggaaggg attattttga cccacatggg
     1261 atgcatattg cagggattct tgctggaaat gatactgaac aagatatcaa aaactttaac
     1321 ggcatagatg gaattgcacc taatgcacaa attttctctt acaaaatgta ttctgacgca
     1381 ggatctgggt ttgcgggtga tgaaacaatg tttcatgcta ttgaagattc tatcaaacac
     1441 aacgttgatg ttgtttcggt atcatctggt tttacaggaa caggtcttgt aggtgagaaa
     1501 tattggcaag ctattcgggc attaagaaaa gcaggcattc caatggttgt cgctacgggt
     1561 aactatgcga cttctgcttc aagttcttca tgggatttag tagcaaataa tcatctgaaa
     1621 atgaccgaca ctggaaatgt aacacgaact gcagcacatg aggatgcgat agcggtcgct
     1681 tctgctaaaa atcaaacagt tgagtttgat aaagttaaca taggtggaga aagttttaaa
     1741 tacagaaata taggggcctt tttcgataag aataaaatca caacaaatga agatggaaca
     1801 aaagctccta gtaaattaaa atttgtatat ataggcaagg ggcaagacca agatttgata
     1861 ggtttggatc ttaggggcaa aattgcagta atggatagaa tttatacaaa ggatttaaaa
     1921 aatgctttta aaaaagctat ggataagggt gcacgcgcca ttatggttgt aaatactgta
     1981 aattactaca atagagataa ttggacagag cttccagcta tgggatatga agcggatgaa
     2041 ggtactaaaa gtcaagtgtt ttcaatttca ggagatgatg gtgtaaagct atggaacatg
     2101 attaatcctg ataaaaaaac tgaagtcaaa agaaataata aagaagattt taaagataaa
     2161 ttggagcaat actatccaat tgatatggaa agttttaatt ccaacaaacc gaatgtaggt
     2221 gacgaaaaag agattgactt taagtttgca cctgacacag acaaagaact ctataaagaa
     2281 gatatcatcg ttccagcagg atccacatct tgggggccaa gaatagattt acttttaaaa
     2341 cccgatgttt cagcacctgg taaaaatatt aaatctacgc ttaatgttat taatggcaaa
     2401 tcaacttatg gctatatgtc aggaactagt atggcgactc caatcgtggc agcttctact
     2461 gttttgatta gaccgaaatt aaaggaaatg cttgaaagac ctgtattgaa aaatcttaag
     2521 ggagatgaca aaatagatct tacaagtctt acaaaaattg ccctacaaaa tactgctcga
     2581 cctatgatgg atgcaacttc ttggaaagaa aaaagtcaat actttgcatc acctagacaa
     2641 cagggagcag gcctaattaa tgtggccaat gctttgagaa atgaagttgt agcaactttc
     2701 aaaaacactg attctaaagg tttggtaaac tcatatggtt ccatttctct taaagaaata
     2761 aaaggtgata aaaaatactt tacaatcaag cttcacaata catcaaacag acctttgact
     2821 tttaaagttt cagcatcagc gataactaca gattctctaa ctgacagatt aaaacttgat
     2881 gaaacatata aagatgaaaa atctccagat ggtaagcaaa ttgttccaga aattcaccca
     2941 gaaaaagtca aaggagcaaa tatcacattt gagcatgata ctttcactat aggcgcaaat
     3001 tctagctttg atttgaatgc ggttataaat gttggagagg ccaaaaacaa aaataaattt
     3061 gtagaatcat ttattcattt tgagtcagtg gaagaaatgg aagctctaaa ctccaacggg
     3121 aagaaaataa acttccaacc ttctttgtcg atgcctctaa tgggatttgc tgggaattgg
     3181 aaccacgaac caatccttga taaatgggct tgggaagaag ggtcaagatc aaaaacactg
     3241 ggaggttatg atgatgatgg taaaccgaaa attccaggaa ccttaaataa gggaattggt
     3301 ggagaacatg gtatagataa atttaatcca gcaggagtta tacaaaatag aaaagataaa
     3361 aatacaacat ccctggatca aaatccagaa ttatttgctt tcaataacca agggatcaac
     3421 gctccatcat caagtggttc taagattgct aacatttatc ctttagattc aaatggaaat
     3481 cctcaagatg ctcaacttga aagaggatta acaccttctc cacttgtatt aagaagtgca
     3541 gaagaaggat tgatttcaat agtaaataca aataaagagg gagaaaatca aagagactta
     3601 aaagtcattt cgagagaaca ctttattaga ggaattttaa attctaaaag caatgatgca
     3661 aagggaatca aatcatctaa actaaaagtt tggggtgact tgaagtggga tggactcatc
     3721 tataatccta gaggtagaga agaaaatgca ccagaaagta aggataatca agatcctgct
     3781 actaagataa gaggtcaatt tgaaccgatt gcggaaggtc aatatttcta taaatttaaa
     3841 tatagattaa ctaaagatta cccatggcag gtttcctata ttcctgtaaa aattgataac
     3901 accgccccta agattgtttc ggttgatttt tcaaatcctg aaaaaattaa gttgattaca
     3961 aaggatactt atcataaggt aaaagatcag tataagaatg aaacgctatt tgcgagagat
     4021 caaaaagaac atcctgaaaa atttgacgag attgcgaacg aagtttggta tgctggcgcc
     4081 gctcttgtta atgaagatgg agaggttgaa aaaaatcttg aagtaactta cgcaggtgag
     4141 ggtcaaggaa gaaatagaaa acttgacaaa gacggaaata ccatttatga aattaaaggt
     4201 gcaggagatt taagaggaaa aatcattgaa gtcattgcat tagatggttc tagcaatttc
     4261 acaaagattc atagaattaa atttgctgat caggctgatg aaaaggggat gatttcttat
     4321 tacctagtag atcctgacaa agatgcttct aaatatgaaa aacttggtga aatttctgaa
     4381 gataaactca aaaatgcaaa gagcccagag gaaaatacca ataataatca agctaaggat
     4441 gaagattcaa aaccagatga aaaaagttca gttgagggag aagctagcct tgaaataaat
     4501 aaaactattt caacaattag agagtttgaa aataaagacc taaagaaact cattaaaaag
     4561 aaatttagag aagttgatga ttttacaagt gaaactggta agagaataga ggaatacgat
     4621 tataaatacg atgataagag aaatattatt gcttatgacg atggtagtgc cttacaatat
     4681 gaaactgaaa aatttgacga aataaaatca aaaatttatg gtgttctaag cccatctaaa
     4741 gatggacact ttgaaattct tggaaagata agcaatgttt ctaaaaatgc caaggtatat
     4801 tatggaaata gctataaatc gatagaaatc aaagcgacta agtatgattc acattcaaaa
     4861 acgatgatat ttgatttata cgctaatatt aatgatattg tagatggatt agcttttgct
     4921 ggagatatga gattatttgt taaagatgac aatcaaataa aagctgaaac taagattaga
     4981 atgcctgaaa aaaataagga aactaaagca gaatatccct atgtatcaag ttatgggaat
     5041 gtaatcgaat taggagaagg agatctttca aagaacaaac cagacaattt aactaaaatg
     5101 gaatctggta aaatctattc tgattcagaa aaacaacaat atctgttaaa ggataacatc
     5161 attctaagaa aaggctatgc actaaaagtg actacctata atcctggaaa aacggatatg
     5221 ttagaaggaa atggagtcta tagcaaggaa gatatagcaa aaatacaaaa ggccaatcct
     5281 aatctaagag tcctttcaga aacaacaatt tatgctgata gtagaaatgt tgaagatgga
     5341 agaagtaccc aagctgtatt aatgtcggct ttggacggct ttaacattat aaggtatcaa
     5401 gtgtttacat ttaaaatgaa cgataaaggg gaagctatcg ataaagacgg aaatcttgtg
     5461 acagattctt ctaaacttgt attatttggt aaggatgata aagaatacac tggagaggat
     5521 aagtccaatg tagaagctat aaaagaagat ggctccatgt tatttattga taccaaacca
     5581 gtaaaccttt caatggataa gaactacttt aatccatcta aatctaataa aatttatgta
     5641 cgaaatccag aattttattt aagaggtaag atttctgata agggtggttt taactgggaa
     5701 ttgagagtta atgaatcggt tgtagataat tatttaatct acggagattt acacattgat
     5761 aacactagag attttaatat taagctgaat gttaaagacg gtgacatcat ggactgggga
     5821 atgaaagact ataaagcaaa cggatttcca gataaggtaa cagatatgga tggaaatgtt
     5881 tatcttcaaa ctggctatag cgatttgaat gctaaagcag ttggagtcca ctatcagttt
     5941 ttatatgata atgttaaacc tgaagtaaac attgatccta agggaaatac tagtatcgaa
     6001 tatgctgatg gaaaatctgt agtctttaac atcaatgata aaagaaataa tggattcgat
     6061 ggtgagattc aagaacaaca tatttatgta aatggaaaag aatatacatc atttgatgat
     6121 attaaacaaa taacagacaa gacactaaac attaagattg ttgtaaaaga ttttgcaaga
     6181 aatacaaccg taaaagaatt cattttaaat aaagatacgg gagaggtaag tgaattaaaa
     6241 cctcataggg taactgtgac cattcaaaat ggaaaagaaa tgagttcaac gatagtgtcg
     6301 gaagaagatt ttattttacc tgtttataag ggtgaattag aaaaaggata ccaatttgat
     6361 ggttgggaaa tttctggttt cgaaggtaaa aaagacgctg gctatgttat taatctatca
     6421 aaagatacct ttataaaacc tgtattcaag aaaatagagg agaaaaagga ggaagagaat
     6481 aaacctactt ttgatgtatc gaaaaagaaa gataacccac aagtaaatca tagtcaatta
     6541 aatgaaagtc acagaaaaga ggatttacaa agagaagatc attcacaaaa atctgattca
     6601 actaaggatg ttacagctac agttcttgat aaaaacaata tcagtagtaa atcaactact
     6661 aacaatccta ataagttgcc aaaaactgga acagcaagcg gagcccagac actattagct
     6721 gccggaataa tgtttatagt aggaattttt cttggattga agaaaaaaaa tcaagattaa
     6781 gacaaaagct atagaaaaaa atggtttatg tactgagatt agatagtgag gtgatgacat
     6841 agttttgtga aaacagccat ttataactca attatttagt ttacttcact attgatacta
     6901 tttggagtta ttaatggact tagtttagat aactaatgaa ttgattgaaa gggttagtat
     6961 tgacaatatt ggtcatattg attagaaaat agagtctatc aaaatttaaa ggctaataga
     7021 ggtgatgaga caatttcaag gaattaagta gcgtttggtt gcttaattcc tttttatttg
     7081 gaaggaagtt tttcgtaacc gcccaataac gaagtctatt ggacggttac gatatgatca
     7141 ctgacttcgt cagtcttatc tacaacctca aaactgtgtt ttgagcaacc tgcggctagc
     7201 ttcctagttt actctttgat tttcattgag tattagaaca gaaaaaatgc ttggagtatt
     7261 tgtttgtgtg tttattttta tataacaaac tataaacaaa aaaaaatata aaaaaagaga
     7321 caaaaaagaa cagaaagtaa ttgacaacgg tttcatatag tgttatactt atggcataaa
     7381 gttaatggaa agaagggaaa acttatggta ttagattatt tctttgacaa aaaccttgtg
     7441 ttttgcttag aagcggataa tcaagaacaa ctctttgatc aggttgcaac tttattggaa
     7501 gaacgagaaa ttgtcactcc aacttatcgt gaagccttga tcacgcgtga aaagtcattt
     7561 ccaactggtt tagatatgga atttctagga aaggacttgc caaatgtagc gattcctcat
     7621 acagatattg ttcataatct agctgagaaa gtggtggttg ttcgattaga aaaaccagta
     7681 acttttcaca atatgatagc tcctgataag gaagtagaag tatccttgct cttctttatc
     7741 atcaataact caagttcaag tcaaacaaat attctggctc agttgatgga ctttttcaca
     7801 ggaaatggac atcttgaaga cctatcaaaa atttccgaac cagaaaaact ttatgcttac
     7861 attgctgaaa caaccgctta atcttgtcta ttaaaaaata aaatcggagg aaatctaaat
     7921 gattaaaatt cttgctgcct gcggtgcagg tgttaactca agtcaccaaa ttaaaagtgc
     7981 tctagaagaa gaactttcaa accgtggtta tgatgttcac tgtgatgcag tcatggtgaa
     8041 agatgtaaac gaagacctta tgaaaggtta cgatatcttt acaccaatcg ctgcaacaga
     8101 ccttggtttt gaaccaggta tcccagttat cgaagctgga ccaatcttat tccgtatccc
     8161 agcaatgagc gctccagtat ttgacaatat tgaagcagct attaaagaac atggattaag
     8221 ctaattctaa tttgttaaca ttcatataac ataaaaaagg gaggaactgt tatggatgca
     8281 atctttgacc taatcggaaa ggttttcaat cccatcttag aaatgggtgg acctgtcatc
     8341 atgttgatca ttttgacagt attggcttta ctttttggag tgaaattctc caaagcgctt
     8401 gaaggtggta tcaaacttgc catcgctctt acaggtatcg gtgctatcat cggtatgcta
     8461 aatggtgctt tctcagcatc acttgcaaaa ttcgttgaaa acactggtat ccaattgagt
     8521 attacagacg ttggttgggc accactcgca acaatcactt ggggttctgc ttggacacta
     8581 tacttcttgc tcatcatgtt gattgtcaac gtagtgatgc ttgctatgaa gaaaaccgat
     8641 acacttgatg tcgatatctt tgatatctgg cacttgtcta tcacaggtct cttgattaaa
     8701 tggtatgctg ataacaatgg tgtgagtcaa ggggtttcac tctttattgc tacagcagct
     8761 atcgtccttg tcggtgtgtt gaaaattatc aactctgact tgatgaaacc tacatttgat
     8821 gaccttctta acgccccaag ttcatcacca atgacatcaa ctcacatgaa ctacatgatg
     8881 aacccagtta tcatggtttt ggataagatt tttgaaaaat tcttcccagg ccttgataaa
     8941 tatgactttg atgctgctaa attgaacaag aaaatcggtt tctggggatc taaattcttc
     9001 atcggtttca tccttggtat cgttatcggt attatgggaa ctccacatcc aattgcaggt
     9061 gttgcagatg cagataaatg gcgtcttgtt atcaaaggat ggttgtctct tggtttgact
     9121 gccggtgtat ctttggaact cttctcactt atcggttcat ggttcatcgc agccgtagaa
     9181 ccactatcac aaggtattac aaacgttgct actaaacgtc ttcaaggacg taaattcaat
     9241 atcggtcttg actggccatt catcgctggt cgtgctgaaa tctgggcttg tgccaacgta
     9301 cttgcaccaa tcatgttgat tgaagcagtg cttctttcaa aagttggaaa tggtatcttg
     9361 ccacttgcag gtatcatcgc tatgggtgtt actccagctc tcttggttgt aactcgtggt
     9421 aaattgctcc gtatgattat cttcggaaca ctcttgttgc cactcttcct tctttcaggt
     9481 acacttattg caccatttgc aacagaactt gctaaaggtg taggtgcctt cccagaaggt
     9541 gtgagccaaa ctcaattgat tactcactct actcttgaag gaccaatcga aaaacttctt
     9601 ggttggacaa ttggtaacac tacaactggt gatatcaaag caatccttgg tgcagtagtc
     9661 ttccttgtat tctatatcgg tatctttgct tggtacagaa aacaaatgat caaacgtaac
     9721 gaagagtacg cagcaaaagc aaaataatgc gctcctataa aatataaact taatgaaaat
     9781 caaagagcaa actaggaagc tagccgcagg tt
//
LOCUS       DAVHLA010000063         9438 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVHLA010000063 DAVHLA010000000
VERSION     DAVHLA010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9438
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.063"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(381..1577)
                     /gene="tuf"
                     /locus_tag="VVO77_001945"
     CDS             complement(381..1577)
                     /gene="tuf"
                     /locus_tag="VVO77_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEU5693906.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(2499..3368)
                     /locus_tag="VVO77_001946"
     CDS             complement(2499..3368)
                     /locus_tag="VVO77_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEU5693907.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTENPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(3592..4212)
                     /locus_tag="VVO77_001947"
     CDS             complement(3592..4212)
                     /locus_tag="VVO77_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU5693908.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVVSGKIDKYKAPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEKPIPQPNPEHPSVPTPNPELPNQETPIPEPTPEPGTPKTETPVNLDPEV
                     PTYETGKREGLSNTGTEANATLASAGIMTLLASLVLGFFKKKEDEK"
     gene            complement(4170..5276)
                     /locus_tag="VVO77_001948"
     CDS             complement(4170..5276)
                     /locus_tag="VVO77_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEU5693909.1"
                     /translation="MNIILIAKPLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVDSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(5387..5641)
                     /locus_tag="VVO77_001949"
     CDS             complement(5387..5641)
                     /locus_tag="VVO77_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693910.1"
                     /translation="MLNVDQDFMSISKSNKSDSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(5999..6532)
                     /locus_tag="VVO77_001950"
     CDS             complement(5999..6532)
                     /locus_tag="VVO77_001950"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEU5693911.1"
                     /translation="MTIFKEQESEKVAEFLDILDNLKDLPIVYIDETGIDRYLYRPYA
                     GAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            complement(6519..6845)
                     /locus_tag="VVO77_001951"
     CDS             complement(6519..6845)
                     /locus_tag="VVO77_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU5693912.1"
                     /translation="MAYNTDFKQGALDSIKGGHRHVEAAKVFWCWRQNSLHVGKERRE
                     QRNLERKKRVVKKRKIPLEELKAFVEAHPDAFLREIAAHFDCAVPSVWAALKQIKVTL
                     KKDDDL"
     gene            7079..8797
                     /locus_tag="VVO77_001952"
     CDS             7079..8797
                     /locus_tag="VVO77_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEU5693913.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKEIMAKFRNNAPKEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            8908..9255
                     /locus_tag="VVO77_001953"
     CDS             8908..9255
                     /locus_tag="VVO77_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEU5693914.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFIHITDGQINVRCDS
                     SMSAQEIKDFAGL"
BASE COUNT         2716 a         1932 c         1769 g         3021 t
ORIGIN      
        1 actattgtat aatgcttttt gatttgagtc tagtattata ctcttcgaaa atctcttcaa
       61 accgcgtcag cttcgccttg tcgtatagat gttactgact tcgtcagttc tatctacaac
      121 ctaaaaacag tgttttgagc agtctgcagc taactttcta taacaaaatg aaataagaac
      181 aagacaaatc aatcaagaca atcaaatcga tttctaacaa tgttttagaa gtagatgtgt
      241 actattctag tttcaatata ttatagtttg ctctttgatt ttcattgagt attagttcaa
      301 tatctaaaaa aagaaccttg ccaagcaaga ttcttttagt gtctgactta aataattgtt
      361 cttctgggaa ctaaatcgaa ttaagcttcg atttctgtaa ccatacctga accaacagta
      421 cgtccaccct cacggataga gaatgtagta ccttgttcta cggcgattgg gtgaatcaac
      481 tcaacgtcga ttgtcacgtt atcaccaggc attaccattt cagtacctgc tggaagttcg
      541 attgaacctg taacgtcagt agtacggaag tagaattgtg gacggtagtt gttgaagaat
      601 ggagtgtgac gtccaccttc ttctttagta aggatgtaga cttcaccttt gaatttagtg
      661 tgtgggttga ttgaacctgg tttagcgata acttgtccac gttcgatttc atcacgttga
      721 acaccacgaa gaaggacacc tacgttatct ccagcaagac cttcgtcaag ttgtttacgg
      781 aacatttcaa caccagtaac aactgctttt tgagtttctt ctttgatacc aacgatttcg
      841 atttcgtcgt tgactttaac gataccacgg tcgatacgtc ctgaagcaac tgtaccacgt
      901 ccagtgattg agaatacgtc ctcgactgga agaagcaatg gtttgtcagt gtcacgttct
      961 ggttctggga tatactcatc aactgtgttc atcaattcca taacgatgtc ttcgtattta
     1021 gagtcacctt caagagcttt aagtgctgaa ccttggataa ctggaagatc gtcacctggg
     1081 aagtcgtatt ctgacaatag gtcacggatt tccatttcaa ccaattcaag caattcttcg
     1141 tcgtcaacca agtcaacttt gttcatgaag acgataaggt gtttaacacc aacctgacgt
     1201 gaaagaagga tgtgctcacg agtttgtggc attggtccgt cagttgaagc tactacaagg
     1261 atagctccgt ccatttgagc agcaccagtg atcatgtttt taacgtagtc cgcgtgtcct
     1321 ggagcgtcga tgtgagcgta gtgacgtttt tcagtttcgt actcaacgtg cgcagtgttg
     1381 atagtgatac cgcgttcgcg ttcttctgga gcagcatcga tagacgcata gtctttaggt
     1441 tggttaactg atgaaggcaa gcgacgtgcc aaaacagttg tgatagctgc agttagggta
     1501 gttttaccgt ggtcaacgtg tccgatagta ccaatgttaa cgtgtggttt actacgatcg
     1561 tatttttctt ttgccatttg agtaaaagcc tccaataaaa tatattttat agatagacag
     1621 taggcaatac agtctaactt tccttactat tttatcaaat ttcagctaaa ttgcaagtgt
     1681 tttacaacgt ttttgtgaat tattcttggt aaaaatttaa ctaattaata gaaagtacta
     1741 aatagactta tccttcaagg agttttcagc attatccatc cactcacttg ctgaaaatgt
     1801 aaacagtctc tggtttatat agtaaaatga aacaagaata gggcaaatcg atcaggacag
     1861 tcaaatcgat ttctaacaat gttttagaag tagatgtgta ctattctagt ttcaatctac
     1921 tatacaacct caaaactgtg ttttgaacaa cctgcggcta gcttcttagt ttgccctttg
     1981 attttcattg agtataaaat tgcagataaa acgataacaa tcataggact cagcagagtc
     2041 aatgtaggtc gaagaatagc ccccctaatc gcttatttta tagcaaaatg aaatagaaac
     2101 tgaacatttt gttgaggaag gtaaatcaat tcctcacaat gtttgagaaa gaagggggga
     2161 ctattccaac ttcaacccac tataaagcag acttacaaga tagggaaccc atctccgata
     2221 atattccgat aatatatagt agaatgaaaa ctgcacaatt tgattggaga attcaaacca
     2281 atttctaaca atgttttaga aacaagggtc tattatttca actgcaacct actatagccc
     2341 attgaagctg gaatagccca ctgagacttc taaaccactg ctggagagga gtttgtttag
     2401 agtttctttc atttccctaa aaaatcaaaa agagagaacc agtctgatcc tctcttactt
     2461 atagatggtg ctcactcaaa tgttaaagga gctatttctt agagataaag gaatttgaat
     2521 acagctactg ccgcaattgc tgctgcgata ggtgctacta ctggtaccca agaataccac
     2581 cattttgaat cgcctttatg ctcaccaaga actgattttg gaaggaaagc atgaaggaga
     2641 cgtggtccca agtcacgggc tgggttcaag gcaggtcctg taggtcctcc aagtgatgtt
     2701 accaaagcca taacgaggaa tccaagtgcc aagtgagcca cagaaagtcc tgaagcagtg
     2761 tgtggagcca cctgtgcttt aatagccaag tcagaaaaat caactgtttg tcctgcttct
     2821 attgcctttt gtttcatgaa ttgaagcact tcagcaccaa agaagttttt agtcaaacca
     2881 agagctgcaa agaacaaaac aaatgaacca acaaactcat taatcaaacc attgacagtt
     2941 gctgcatagc gactttcttt tgtaccatgg tcaatacttg aaatagttga gaaagttccc
     3001 aagatgttat ttgggttttc agttttcaag tagaatggac ggtatgttgc cacaactaag
     3061 gcttggccaa agatagcccc caagacttgc gcgataatgt aaggtaccac ttgtgcccaa
     3121 gggaaaagac cgctaactgc aagccctaga gtgaaagcag ggttgatgtg attcccagat
     3181 acgttaccaa acatcaaggc tgggatcata acccccatac cataaccaac agcgatgacg
     3241 atccagccac tttggtgacc tttcgtacct ttaagttcaa cgttggcaac tgcaccattc
     3301 ccaagaatga tcaaaatggc agttcccaaa aattcagtgg catacttcag tgcccatgtg
     3361 aaatccattt gctagattct ccttaaaatt ttttagatat tccttatttt atcaattttt
     3421 accctattta gcaactgatt tctggaaata tttttaaaaa aataggattc atagtttccc
     3481 agttcaacgg acttgtaagc gtttttattc ttcacgaaag acctcgttct caaaaccagg
     3541 aaaaaagccc acatctgtga gcttttcctg gttcctagat tctaaaatct attatttttc
     3601 atcttctttt ttcttgaaga atcctaatac tagactagct aacaaggtca tgataccagc
     3661 actagccaag gtagcattag cttctgtacc tgtgtttgac aatccctctc tcttacctgt
     3721 ctcataagtc ggaacttctg ggtctagatt cactggagtt tcagtttttg gagtacctgg
     3781 ttctggagtt ggctctggta ttggagtctc ttgatttggt agttctgggt ttggtgtcgg
     3841 aacacttgga tgctctggat ttggttgtgg gattggtttt tctggagttg gtttatctgg
     3901 tgttgataaa cggtcatacc ttaccgttat ttctttatca ctagagtctg acgtaacttc
     3961 ttgtgattca actgttggaa tatctggagc tttgtacttg tcaatcttac cagatacaac
     4021 ctcgtcccag tttcctgttg tccattcacc gtaggttaca actcccgtga ccttgttctc
     4081 agtttttgta cggcttaagg ttacaggttg aacaacatct tcttttacat tttggttcgt
     4141 aactttatca acgtaatgaa tgatacgcgt tatagtcttc gtctcagtag aggttgctgt
     4201 tttgggaacc actgtttcct caacattctc acggtagtaa tagtcaactg ttgcaccgtc
     4261 ttctggtacg catttgcagg agttgctacc aaggtgtatg ttgttttcct tgtgataact
     4321 cggtcttctt tgtcctcagt tgttgttttc ccttcaatag tttttgattc tgtggtatac
     4381 tcagaaccta tcgctaaatc agcttttata acagactctg ccaacttctc ttggctacct
     4441 tctttatagt aattggctgt tactgtagca gtggttggcg cttcgctttc tctataaact
     4501 aaggtcactg ttctaccttc gcttacaata ttcccagtta aacttgcaga atttgtatct
     4561 gcttctttaa aagtataata ttttccgtca gtagtagtca tgctactgag ttttttatct
     4621 gtgacattgt agctggtacc aatcagttgt tttttattgg taatgtaggt tccgtcactt
     4681 tctttttctc caattccagt atcatttttc aatgatagca aacgcccttg ttcatcaaca
     4741 tagcgaactt tcacattttc tgagattagt tctgccaatt ctgaggtttt tttctttttc
     4801 ttgatttctt cggttatttt ccctttctct tcttcgggaa tatttagttt tggaatgatt
     4861 ttttcaacaa cggttcgtga tggttccaca gtatcttgga tgactgaaaa gtcagctaga
     4921 attgggagat tatactgaac acggtgactt tgagtgttta ctcctactct ttcattattc
     4981 tctgaaaata cttgtacggt ataagaaaca acatcttttc ctaatagaac atccccagta
     5041 gagaaatagc cgccttttcc tagtttgcta tctccagagt ccacttcttt cctaatctta
     5101 tcagatagtt ttttaccagt cagtacattc gttcgcacaa tccctttgtc tacccctaca
     5161 aagtgggaga actttttgaa ctcttcagaa ccagatctag cccaaccatt attaagggca
     5221 tttgcttttg tatttgtatt ctctctcaaa ggtttggcga ttagaattat attcatcggc
     5281 acttagagtt gctgctatat ctgactcttg aataccaact tccttactac catttctagc
     5341 ggcagtatat gtgtatttat ctgtttctac ttctagctga ttatccttaa catgataggt
     5401 aattttctcc tggtataaga gtcttcagta gtttatatgc tctgtcatca tctttagctt
     5461 tagaagcagc tgagtttagc caagttgggg tattaggagt atctttatca gcctgtttca
     5521 agacattatt caagtcattt gctaacctat tggttgtcct cactgtgaaa gttttcttcc
     5581 agtctgaatc acttttatta gacttagata tgctcatgaa atcctggtca acattcaaca
     5641 caatatcgcc ttgtttttta gcatcttccg ttgcttctgc ttcaaattga tcatggagtt
     5701 tttgttgctc tggtgtatag tttttttatt tacacgattt aatgtactat tttttatttt
     5761 agtattaaga actccattaa tacgattttt aaattctgct tcaaaaaatc ccttaatttg
     5821 ttggtgcgca agttcaacat tcaaaccttt cttatacaag tcttcattct gatacaagtc
     5881 ttcattctga acgatttcgg ctacacggtg aatggtttga tcgtataccg tcttctctta
     5941 accagcagta tccttagttt taatgactac tcgataggtt cctttagaac cgttatagtc
     6001 atctagtttt aaaaaagcat tccaaacatt caaaaatagt tggaacttcc cttaataaat
     6061 ccgtcacttt ctttttcaag atagcccaag cttgctcaat aggattcaaa tccggtgaat
     6121 aaggtggtag aggtaagaaa aagtgtttat cttggatgca gagttcatcc aaaatgttct
     6181 tgggatgaaa actagcattg cccatgacaa taacatgagg tgtcttcaaa gcaggtagga
     6241 gttgcgtttt gaaccactcc acaaagaaat cgcttgtcat gcttttcttg taaatcatgg
     6301 gagctataaa ctctccgtct acttgtcctg caacaattga agttcgctca aaacgacgtc
     6361 cgctaatctt ttcatagact ttctcccctc taggagcccc tgcataagga cgatagaggt
     6421 agcggtcgat tcctgtttca tcaatatata cgattggtaa atcttttagg ttatccaaaa
     6481 tatcaagaaa ctcagcgact ttctctgact cttgttcctt aaagatcgtc atcttttttt
     6541 aaagtgacct taatctgctt taaagctgcc catactgaag gaacagcaca atcaaaatgt
     6601 gccgcaattt cccgtaaaaa agcatctgga tgagcctcta caaaggcttt caattcttct
     6661 aaagggatct tacgcttttt gacgactcgc tttttccgct ctaagttcct ttgttcacgt
     6721 ctttcttttc ccacgtgaag agagttctga cgccaacacc aaaaaacttt ggccgcctcg
     6781 acatgtctgt gccctccttt gatggaatct aatgctcctt gtttaaaatc agtattatat
     6841 gccatagctt tattagacca tgcttatttt aaactaagca actatatcaa tgttttgtta
     6901 tgagaagact tacttttttt actgaaattg aatttttcct agcctcaaca tcatataacc
     6961 ccaaaattca atctgacctg gtttgaagag atgttcgaag cagataaggt tttactaaaa
     7021 ctaaaaaaaa tgatataatc aaactgatta aatgttttaa aaataaagga gaatttgaat
     7081 gtcttaccaa gaaaattacc agaaatgggt tgattttgtg gagcttcctg actaccttcg
     7141 tcaagatttg gaaaatatgg acgaaaaaac taaggaagat gccttctata caaatcttga
     7201 atttggtact gcaggtatgc gtggcttggt tggtgctggt acaaaccgta tcaacatcta
     7261 cgttgttcgc caagctactg aaggattggc tcgtttgatt gagtcaaaag gtggaaacga
     7321 gaaagaacgc ggtgtagcaa ttgcctacga tagccgtcac ttctcacctg agtttgcctt
     7381 tgaatctgcg gcagttcttg ctaaacacgg catcaaatct tacgtatttg aaagccttcg
     7441 tccgactcca gaactatcat ttgcagttcg tcatctcaac tgtttcgcag gtatcatggt
     7501 cacagccagc cacaaccctg ctccatttaa cggttacaag gtttacggtg aagacggtgg
     7561 acaaatgcct ccacacgatg cggacgcttt gactacttat atccgtgcaa tcgaaaaccc
     7621 atttgcagtt gaagttgctg atgtggaaac tgaaaaagct tctggcttga ttgaagttat
     7681 cggcgaagct gttgacgtag aataccttaa agaggttaag gacgtaaaca tcaacccagc
     7741 cttgattgaa gaatttggta aagacatgaa gattgtctac acaccacttc atggtactgg
     7801 tgaaatgttg gctcgtcgtg ctcttgccca agcaggattt gactctgttc aagttgttga
     7861 agcgcaagca actgctgacc cagacttctc aactgtaaca tctccaaacc cagaaagcca
     7921 agcagccttt gcccttgctg aagaacttgg tcgtcaagtt ggtgcagatg ttcttgtcgc
     7981 aactgaccca gacgctgacc gtgttggtgt tgaagttctt caaaaagatg gtagctacct
     8041 caacctttca ggtaaccaaa tcggtgctat catggctaaa tacatcttgg aagctcacaa
     8101 aaacgctgga actcttcctg aaaatgccgc tctctgcaaa tctatcgttt caactgactt
     8161 ggtaacgaag attgctgaaa gctacggcgc aactatgttc aacgtcttga caggtttcaa
     8221 atttatcgct gaaaaaatcc aagaattcga agaaaaacac aaccacactt acatgatggg
     8281 atttgaagaa agcttcggtt acttgattaa accatttgta cgtgataaag atgccatcca
     8341 agccgttctt gtcgttgctg aacttgctgc ctactaccgt tctcgtggtt tgacacttgc
     8401 tgacggtatc gaagaaatct ataaagaata tggctactac gcagaaaaaa caatctctgt
     8461 tactctttca ggtgtcgatg gtgctgaaca aatcaaagag attatggcta aattccgcaa
     8521 caatgctcca aaagaatgga acgcaacagc tatcactgtc gtagaagact tcaaggcaca
     8581 aactgctact gttgctgacg gtactgttac aaacttgaca actcctccaa gtgatgtgtt
     8641 gaaatacaca cttgctgacg gttcatggat tgccgttcgc ccttcaggta cagaaccaaa
     8701 aatcaagttc tacattgcag ttgtagggga aaccaacgaa gaatcacaag ctaagattgc
     8761 taacatcgaa gcagaaatca atgcatttgt aaaataaaga cctataaaag atgagaccaa
     8821 ccaacctcat cttttttcgt atcaaatcta agcaatttta gaaactttat ggcatactag
     8881 acttatcaat gaaagcgagg taatctcatg gaacaatttt tagataacat caaagacctt
     8941 gaagtcacta cagttgtgcg tgcgcaagaa gctcttgata aaaaagaaac tgcaaccttc
     9001 tttatcggtc gcaaaacttg cccttactgc cgtaaatttg caggtacatt gtcaggtgtc
     9061 gtagctgaaa ccaaagctca catttacttc atcaatagtg aagaaccaag ccaactcaat
     9121 gatttgcaag cattccgctc acgttatgga atcccaactg taccaggttt tattcatatt
     9181 acagatggac aaatcaacgt ccgttgcgac tcttcaatgt cagcacaaga aatcaaagat
     9241 ttcgcaggat tgtaaaaaat cagctaacaa gtcttaaaat cacaaaaacg cataatgtaa
     9301 ggtgcaaaaa ccttgatatt atgcgtttta ttgttcctaa aacagttaca tcagtatttc
     9361 attacagaac attttaattt tggaagtcaa atcaattttt aacaatgttt tagaaatcac
     9421 agtgggctat tccatatt
//
LOCUS       DAVHLA010000064         9226 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVHLA010000064 DAVHLA010000000
VERSION     DAVHLA010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9226
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.064"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            168..854
                     /locus_tag="VVO77_001954"
     CDS             168..854
                     /locus_tag="VVO77_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEU5693915.1"
                     /translation="METKKIKNLKGQIIVSCQALEGEPLYTPNGGVMPLLAKAAFQAG
                     AKGIRANSVRDISEIKEEVDLPIIGIIKRDYDGFEPFISATMKEIDELVSEGVDILAL
                     DCTNRSRPGYDNITDFIHDIKVKYPNQLLMADISTFEEGKVAAESGVDFVGTTLSGYT
                     PYSPKKDNPDFELVERLVKELDVPVIAEGRISTPEQARKMLDLGAYAVVVGGAITRPL
                     EIAKKFIEVV"
     gene            855..1787
                     /locus_tag="VVO77_001955"
     CDS             855..1787
                     /locus_tag="VVO77_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001071049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU5693916.1"
                     /translation="MNQEILKKSKIQLTVEHIQKYWILYLMMIPATVLLILFTYGPMY
                     GIIMAFQDFTVFKGYTGSPFVGLKHFQRLFSDPLFYRLFKNTFMVGVLDFLFSFPAPL
                     IFALILNEVRKVRFKSVVQSISYLPHFIPLVVMVGIIFELFGSYGIINSLLSSLGMEP
                     ISFFTKSEWFLPLYIGSGVWKTIGWGSIIYMGALTNIDSTLYEAADMDGANRWHKMWH
                     VTLPSLRPTVVTLFILNAGGIMQVGFEKVFLMSSPATYEVSDVLSTYVYRQGILNSDF
                     SYSAAVGLFNNIVALLFVLLANKIAKKLGEEGIV"
     gene            1798..2727
                     /locus_tag="VVO77_001956"
     CDS             1798..2727
                     /locus_tag="VVO77_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000577774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU5693917.1"
                     /translation="MIFSKNTKKSNRDKETFVDYLFIFILIIITLLMLYPLWWVVMTS
                     LSEPVWLSKNVVKLFPLKIDITAYKFIFGDSKLWQAYGNSVLYAALSTIVSVAVCSMY
                     AYPLTIPEIRGKKFWNTLILIPMFFSGGMIPLYIQVANLGLLNTAWALVLPGAVSTYY
                     IILFRTQFKSIPMELRESARIDGASEFRIFWNLVLPLSKVIFMIIALYCIVGSWNSFT
                     PPLLYLNDDTKMPLSIYLRNLVVTNTTDTAELSLSAGNTYYQQIAAQGGGIGMRIAIK
                     MGTIVVSVIPIMMIYPFIQKHFVKGILLGSVKG"
     gene            2741..4180
                     /locus_tag="VVO77_001957"
     CDS             2741..4180
                     /locus_tag="VVO77_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001178946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693918.1"
                     /translation="MQNLKKYLLLDSGLVVGYTLENAQLKLNKLKKDTENNPLFGEEY
                     FAENPKLWEVRFDNSYPNVIYDKELKLYRCWYQTFVSDEASEETPLAERGEKEYIVKS
                     SRMTALCYAESKDGVKWEKPNLNLVKFKGSKDNNIVLMHAHGAGIMLDEQELDPKKRY
                     KLVSKLEFSPNLHYMVVVFSEDGIHFDEPIPWKKWNPAADSHNFPFRDPKTGKYAVIT
                     RTWANNVRLSAITFSDDFINWSEPKEILRGDGFEDQIYSMPVISYADIYLGFASMYHE
                     GDTLNENYDKVDLELKFSANLEQWDSVCKGDYLIERGGGVYPQNADFDASCIFTAAPI
                     IEDDKIWFYYMGGNGNHTGFRESSLARGYIKKDQFAYYTNKREGIPAKISTVSFQTYD
                     DEIYILADIPENGYIKVAVGTKYGNAYSDFGQEDISLVQVSDGKYKLEFNKKSILDLG
                     NSPVAFKFEIENAKLYGIEGSIQQHYLKY"
     gene            4249..5826
                     /locus_tag="VVO77_001958"
     CDS             4249..5826
                     /locus_tag="VVO77_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU5693919.1"
                     /translation="MVKLNKVLKGSVAFLSASLLLAACGNNANSKPAEKTADGKTKIS
                     FLSTWQINDVRPPKDETLVGQWLEEQLGIDIDLVTIPGEGVSSKVNSLITSNQLPTVL
                     LTTGDKSDIAGINKLGKQGAFLDLSQHMDKLPNYKKYLEKNNALAQIEDDEKHIYAFT
                     KFFTDENIMYTTPILRKDLLVGSEFEDLSKIKTVDDYTKVLKYLTEKQGSPAFIQRNG
                     YEGFMKRVTPLWNLSHRTYYDYESDSYKHPVEQPQLKQFVEWLKELRKDNVLHPDWAV
                     MKDETWEGLLASNKGSFTVDRMNIIGDNNFDKSFDWQPLVYPKINGKRYLQPKTPYIS
                     DSGWVINANAPKEEIDKALEFFNFLYADENQEKLAIGFEGKTFTRENPNTQAGIKWLI
                     QIYGENAGNDKAELLFKHGNQAFTRVQTKLDIEAQPGTFPKVMYDQVDKIKKDLGGFR
                     PDTPVLSFTTEELDVLTKSEAGLNTFFDENIIKFIEGQRDMSEWDSFINEAKSKDLDK
                     VTKVYNDAYKRVKDRMK"
     gene            5886..7346
                     /locus_tag="VVO77_001959"
     CDS             5886..7346
                     /locus_tag="VVO77_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEU5693920.1"
                     /translation="MYDVVIIGAGSSGALAAIASGRLGLKTCLIEKGSRIGGVPINTL
                     MGSFANLYFDDSGRVNASKIVGELIERIIKKGGTVFNSMEELMNVNDFYQITIPYQPE
                     VYESVLTDMLIESKVDILLNIEVNNIIYDSKNIKSLEILSNQEVKLIDSKVFIDATGN
                     ATIASASGADVYEKNSSYGCLMRVGGVDISKTIEHIEKTKQWNYIEGYNQWLEEVLAN
                     RKYRATGAVLKDPVSYDHAPMLSKDDHFMNDEKWNYIKERWEKFRFIYTLEVSLFRNE
                     LKKAVESGDFNFEIYHDDKSGVTMNGDGISYGSWGQNVALINVAKAFGFNPKYMEDES
                     HANILSRKYNLTFLSFLKKYVPGFENSFILDQGTRATNRSCRHIDNSSMMDEILDFPM
                     YTFKTMYSYQTPKEITYKSIVGGKLNNLFVIGKGAYQSESFRSQISCMLMGISSAAAA
                     KTIIEDKSNTLNINRDLFKSNLDILFTWEFSNWITD"
     gene            7368..7823
                     /locus_tag="VVO77_001960"
     CDS             7368..7823
                     /locus_tag="VVO77_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001000318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT domain-containing protein"
                     /protein_id="HEU5693921.1"
                     /translation="MNDTNKNQYFVYEFDTSFVEMSYSQFFEGYCILFSKEPYPSLSD
                     MPMEFRKEFLMEMSILGDAMLEVLNAYRINYDILGNSTPVLHAHLFPRYMWEEEERRK
                     TVVHRYDSSVFSNPEFEFTIEKHGPIIKKLRSAIDRHYREYQQLLDDSN"
     gene            7910..8316
                     /gene="cdd"
                     /locus_tag="VVO77_001961"
                     /pseudo
     CDS             7910..8316
                     /gene="cdd"
                     /locus_tag="VVO77_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221146.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
     gene            8329..8778
                     /locus_tag="VVO77_001962"
     CDS             8329..8778
                     /locus_tag="VVO77_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEU5693922.1"
                     /translation="MELVEFKNGHVNTVHEHIAITKVKEFLNNHDIPKDKGGIHKIST
                     DFFYNIIDMETTTEENRPWESHKEYYDVHYLLNGEEIILYNFLSQMELSEYKVDDDWQ
                     QMNGTALFSIKLKKDMLLLLEPNDAHKTGLLVEEPLNIKKVVFKVKI"
     gene            complement(8890..>9226)
                     /locus_tag="VVO77_001963"
     CDS             complement(8890..>9226)
                     /locus_tag="VVO77_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU5693923.1"
                     /translation="TEWMNVFLEELSQAYPDDYFLLVMDNAIWHKSSILKIPTNIGFA
                     FIPPYTPEMNPIEQVWKEIRKRGFKNKAFRILEDVMNQLQDVIQGLEKEVIKSIVNRR
                     WTRMLFESR"
BASE COUNT         3199 a         1224 c         1715 g         3088 t
ORIGIN      
        1 gtgtattgaa tctataacag tacgccttaa atgctaaaat atttctataa attaatttaa
       61 ctttcctgat agggctgttc atatcttatt tcaattcact atataaataa aattgtagta
      121 gatgttattg aattagtaaa aaaaataaaa aaacggaggt tttctgaatg gaaactaaaa
      181 aaattaaaaa tttaaaaggt caaataattg tttcctgcca agcgttagaa ggagagccac
      241 tttatactcc aaatggagga gtgatgccgt tattagcaaa agccgccttt caagcaggcg
      301 ctaaaggtat tcgtgctaat tctgtccgcg atatttcaga aataaaagaa gaagttgact
      361 taccaattat aggtatcata aaaagagatt acgatggctt tgaacctttt atttcagcaa
      421 ctatgaaaga gattgatgaa ttagttagtg aaggagtaga cattttagct ttggattgta
      481 ctaatcgttc aagaccaggt tatgataata ttactgactt tattcatgat attaaagtca
      541 agtatccaaa ccaattatta atggctgata tttctacttt tgaagaaggg aaagtagctg
      601 ctgaatcggg agtagatttt gtgggtacga cattatctgg ttatacacca tatagcccta
      661 aaaaagataa tcctgatttt gagttagttg aaagattggt aaaagagctt gacgtaccag
      721 ttattgctga aggaagaata agtactccgg aacaagctag aaaaatgtta gatttaggtg
      781 cttacgcagt ggttgttgga ggagctatca ctcgtccttt ggaaatagcg aagaagttta
      841 ttgaggtagt ttagatgaat caagaaatat taaaaaagag taagattcaa ttgacagttg
      901 aacatattca aaaatattgg attttatatt taatgatgat tccagcaact gttctactaa
      961 ttttatttac gtatggacca atgtacggca ttattatggc ctttcaagac tttactgtct
     1021 tcaagggata tactggaagt ccatttgtcg gtttaaaaca ttttcaaaga ttgttctcag
     1081 atcctttgtt ttatagattg ttcaagaata cgttcatggt aggggtttta gactttttat
     1141 tctctttccc agctccgctt atttttgcac tcatattaaa cgaagtcaga aaagtaagat
     1201 ttaagagtgt agttcaatct attagttatc ttcctcattt tattccccta gtggttatgg
     1261 ttggtattat ttttgaacta tttggttcat atggtattat taacagttta ctttcatcac
     1321 ttggaatgga gccaataagt ttctttacaa aatctgaatg gttcttgcct ctctacattg
     1381 gttcaggagt atggaaaaca ataggttggg gttctatcat ttatatggga gcattaacca
     1441 atatagattc aactttatat gaagcagcag atatggacgg ggctaataga tggcacaaaa
     1501 tgtggcatgt aactctacca agtttaagac ctacagtagt tactttgttt atactaaatg
     1561 ctggtggtat catgcaagta ggatttgaaa aggtattctt gatgtctagt cctgcaacat
     1621 atgaagtatc tgatgtatta tctacttatg tttatagaca aggtatttta aattctgatt
     1681 tcagttactc agctgcagta ggattattta ataacatagt agctttgtta tttgttttat
     1741 tagctaataa gattgctaaa aaacttggcg aagaaggaat tgtataaggg gggtaaaatg
     1801 attttttcaa aaaatacaaa aaagagtaat agagacaaag aaaccttcgt tgattatctc
     1861 tttatattca ttttaataat aataacctta cttatgttgt atccattatg gtgggtagtg
     1921 atgacgtcac tttcagaacc agtttggcta tctaaaaacg ttgttaaatt atttccctta
     1981 aaaatagata ttactgcata taagtttatt tttggggatt ctaaactatg gcaagcatat
     2041 ggtaatagtg tattgtatgc tgcactatct acaattgtta gtgttgcggt atgtagtatg
     2101 tatgcctatc cacttacaat tcctgaaatt aggggtaaaa aattctggaa tactcttatt
     2161 ttgattccaa tgttctttag tggaggaatg atcccgcttt atatacaagt tgcaaacctc
     2221 ggtttattga atactgcttg ggctcttgtt ttacctggtg ctgtttctac atattatata
     2281 attttgttta gaacacagtt taaatcaatc ccaatggagc ttcgtgagtc tgctagaatt
     2341 gatggggcaa gtgaatttag aattttttgg aatttagtat taccattatc aaaagttatt
     2401 ttcatgatta tagcacttta ttgcatagtt ggttcatgga atagttttac tcctccatta
     2461 ctttatttga atgacgacac taagatgcct ttatctattt atttgagaaa tttagttgtt
     2521 acaaatacaa ctgatactgc tgaattatca ctttctgcag gtaatacata ttaccaacaa
     2581 attgctgctc aaggtggagg tattggtatg cgtattgcta ttaagatggg tactattgtt
     2641 gttagtgtta ttccaattat gatgatttat ccatttattc agaaacattt tgttaaggga
     2701 atcctgctag gttctgtgaa aggttaataa ggtaattatt ttgcaaaatt taaaaaaata
     2761 tcttttatta gatagcggtt tagtagttgg gtatacatta gaaaatgctc aattaaaatt
     2821 aaataagcta aaaaaagata ctgaaaacaa tccactattt ggtgaagagt attttgccga
     2881 aaatcctaaa ttatgggaag ttcgttttga taattcatat ccaaacgtta tctatgataa
     2941 agaattgaaa ttatatagat gttggtatca aacatttgtt agtgatgaag caagcgaaga
     3001 gactccttta gcagaacgtg gagagaagga atacattgtc aagtcatcta gaatgacagc
     3061 actttgctat gctgaaagta aagatggagt aaaatgggaa aaaccaaatc tcaatctagt
     3121 aaaatttaaa ggttcaaaag ataataatat tgttctgatg catgcacacg gtgcaggtat
     3181 catgctagat gaacaggagt tggatcctaa gaaacgatat aaattagttt caaaattaga
     3241 attttctccg aatcttcatt acatggttgt tgttttttca gaagacggta ttcattttga
     3301 cgaacctatt ccatggaaaa aatggaatcc tgcagcagat agtcataatt ttccatttag
     3361 agatccaaaa actggtaaat acgctgttat tacaagaacc tgggcaaata acgtacgtct
     3421 aagtgcaatt actttcagtg atgattttat taattggtca gaacctaaag aaatccttag
     3481 gggagatgga tttgaagatc aaatttattc tatgccagta atttcatacg cggatatcta
     3541 tttaggtttt gcttcaatgt accacgaagg cgacacttta aatgaaaact atgataaagt
     3601 agacttagaa ttgaaattct ctgctaattt ggaacaatgg gatagtgtat gtaagggcga
     3661 ctatctcatt gaaaggggag gtggagtata cccgcagaat gctgattttg atgctagttg
     3721 tattttcacg gctgctccaa taattgaaga tgataagatt tggttctact atatgggtgg
     3781 aaatggtaat cacactggct tccgagaaag ttcattagct agaggatata ttaagaaaga
     3841 ccaatttgct tattatacta ataagagaga aggaattcca gctaaaatat ctacagttag
     3901 cttccaaact tacgatgatg aaatttatat cttagctgat attcctgaaa atggttatat
     3961 taaagttgcg gtaggtacta aatacggtaa tgcttattca gattttggtc aggaagatat
     4021 ctctcttgtt caagtttccg atggtaagta taagttggaa tttaataaaa aatctatctt
     4081 agatttaggt aattctccag ttgcgttcaa atttgaaatc gagaatgcaa aattgtatgg
     4141 tattgaaggt agtattcagc aacactatct caaatattaa ccagaataat tcgttaacaa
     4201 ataatctcta tattagtgga gatagatata taaaatggag gtcttattat ggtaaagctt
     4261 aataaggtat taaaagggag tgttgcattc ctgagtgcaa gtttattgct agcagcttgt
     4321 ggcaataacg ctaattcaaa gcccgctgaa aaaacagctg atggtaaaac gaaaatttcg
     4381 tttctatcta catggcaaat taatgatgtt cgtccgccta aagatgaaac acttgttggt
     4441 caatggttag aagaacagct aggtattgat attgatcttg taactattcc tggcgaggga
     4501 gtaagttcta aagtaaattc tcttattact agtaaccagt taccgactgt tttgttgaca
     4561 acaggagata agagtgatat cgctggtatc aacaaacttg gtaaacaggg tgcattctta
     4621 gatttgtcac aacacatgga caaactacca aactataaga agtaccttga aaaaaataat
     4681 gcattagctc aaatagaaga tgatgaaaaa catatttatg ctttcacaaa attctttact
     4741 gatgagaata tcatgtatac tacaccaatt ctgagaaaag acttacttgt tggttcagaa
     4801 tttgaagatc tttcaaaaat taaaactgtt gatgactata caaaagtttt gaaatatttg
     4861 actgaaaaac aaggttctcc agcatttatt caacgtaatg gctatgaagg cttcatgaag
     4921 cgagttacac cattgtggaa tttaagccat cgtacatact atgactatga atcagattca
     4981 tataaacatc cagttgaaca acctcaattg aaacaattcg ttgaatggtt gaaagaatta
     5041 cgtaaagata acgtacttca ccctgactgg gcagttatga aagatgaaac ttgggaaggt
     5101 ctattggctt ctaacaaggg ttcattcact gttgaccgta tgaatatcat tggagataat
     5161 aactttgata aatcatttga ttggcagcca cttgtttatc caaaaattaa tggaaaacgt
     5221 tatttgcaac cgaaaacacc gtacatttct gattcaggtt gggtaatcaa tgccaatgca
     5281 ccaaaagaag aaattgataa agcgttagaa ttctttaatt tcttatacgc tgatgaaaat
     5341 caagaaaaac ttgctattgg atttgaaggt aaaacattta cacgtgaaaa ccctaatact
     5401 caagcaggta ttaaatggtt gattcaaatt tacggtgaaa atgctggaaa tgataaagca
     5461 gaactgctgt ttaaacatgg taaccaagca tttactcgcg ttcaaactaa attagatatt
     5521 gaggcacagc caggaacatt ccctaaagtt atgtatgatc aagtagataa aattaagaaa
     5581 gatttaggtg gttttagacc agatactccg gttctttcct ttacaactga agaattagat
     5641 gttttaacta aatctgaagc aggattaaat actttctttg atgaaaatat tattaaattc
     5701 attgaaggac aaagagatat gagtgagtgg gattcattta tcaatgaagc taaatctaaa
     5761 gacttggata aagttacaaa agtatataat gatgcctaca aacgtgtcaa agatagaatg
     5821 aaatagacta aatggtagct ctctggtttt tcagagagct actactgcct gagggggagt
     5881 aagctttgta tgatgtagta attataggtg caggaagttc gggcgcattg gctgcaattg
     5941 cttcggggcg tctagggtta aaaacttgtc taatagagaa gggaagtaga attggtggag
     6001 ttcctattaa tacactaatg gggtcatttg ctaatctata ttttgatgat tctggtagag
     6061 taaatgcaag taaaattgtt ggggaattaa tagaacgtat tatcaaaaaa ggtggtactg
     6121 tctttaactc tatggaagaa ttgatgaatg taaatgattt ttatcagatt acaattccct
     6181 atcaaccaga agtttatgaa tcggttttaa ctgatatgtt gattgagtct aaagttgata
     6241 ttttactaaa tattgaagtt aataatatta tttatgatag taaaaatatt aaaagtcttg
     6301 aaattttaag taatcaggaa gttaaattga ttgattctaa agtttttatt gatgctacag
     6361 ggaatgcaac aattgcttct gctagtggag ctgatgttta tgaaaaaaat tcttcttacg
     6421 gttgtttaat gagagttgga ggagttgata tctcaaagac tatagaacat attgaaaaaa
     6481 caaagcagtg gaactatata gaaggatata atcagtggtt agaagaagta ttagcaaatc
     6541 gaaagtacag agccactgga gcagttttaa aagatccagt ttcttatgat catgccccta
     6601 tgctttcaaa agacgaccat tttatgaatg atgaaaaatg gaattacatt aaagaaagat
     6661 gggaaaaatt tagatttatt tacactttag aagtatcact atttaggaat gaattaaaaa
     6721 aagctgtaga atctggggat tttaattttg aaatttatca tgatgataaa tctggagtca
     6781 ctatgaatgg cgacggtata agctatggtt catggggtca aaatgtagca ttaattaatg
     6841 ttgcaaaagc atttggattc aatcccaaat atatggaaga tgaatcacat gctaatattc
     6901 tttctagaaa atataattta acatttttat cttttcttaa aaaatatgta ccaggttttg
     6961 aaaattcttt tatccttgat cagggaacta gagctactaa cagatcatgt aggcacattg
     7021 ataattcatc tatgatggac gaaattcttg attttccaat gtatacattt aagactatgt
     7081 atagctatca aactcctaaa gaaataacgt acaaatcaat tgtaggtgga aaattgaata
     7141 atttgtttgt aataggtaaa ggtgcttacc aatccgaaag ttttagatca caaattagtt
     7201 gtatgttaat ggggatatca tcagcagcag cggcaaaaac tattattgaa gataaaagca
     7261 atactctaaa cattaataga gatttgttta aatcgaactt agatatatta tttacatggg
     7321 agttttctaa ttggattact gattaacaaa taataaggga atattaaatg aatgatacta
     7381 ataaaaatca atactttgtt tatgaatttg atactagctt tgtagaaatg tcttattctc
     7441 agttttttga aggatattgt attctttttt caaaagaacc ctatccttct ttatctgata
     7501 tgccaatgga atttagaaaa gaatttttaa tggaaatgag tatattaggt gatgcgatgc
     7561 ttgaagtgtt aaatgcctat agaattaatt atgatatctt aggaaattca acacctgtac
     7621 ttcatgctca tttatttccg agatacatgt gggaagagga agagagaaga aaaactgtag
     7681 ttcatagata tgattcttca gtttttagca atcctgagtt tgaatttact atagaaaagc
     7741 atggaccaat tattaaaaaa ctgaggtctg ctattgatag acattataga gagtatcaac
     7801 aattattaga tgattcaaac tgaactccac attttcgatt agatttaata ccttgtatat
     7861 tacaactagg ttgtggatga tataattttt tgaaaaatat attttaggaa tgacttataa
     7921 agcaattata tcagaggcta ttaaatcaat ggccaaagct tatgctcctt attctgattt
     7981 taaggttgga gctgcgttag taactgaaga taaaaaattt tttctggatg taatatagaa
     8041 aatgctgctt tttctcctac ttgctgtgca gaacgagtat ctttttataa agctgtattt
     8101 aaaggagaac gttcgttttc aagaatatgt attgtaggtg gaaaaaatgg tatcttatca
     8161 tcttttatag caccttgcgg agtgtgtcgc caggtaatga tagaattttg taattctgat
     8221 tcatttgaag ttatattggc tagtgatgtt gatacttata aagtatataa acttaaagaa
     8281 ctactaccag ttagttttaa tcaagaaaat ttataacagg agggaactat ggaattagtt
     8341 gaatttaaaa atggacatgt taatacggtt catgagcata tcgcaataac gaaagtaaaa
     8401 gagtttctaa ataatcatga tataccaaaa gataaaggtg gcatacataa aatttctact
     8461 gatttctttt acaatataat tgatatggaa actacaactg aagagaatag accgtgggaa
     8521 agtcataagg aatattatga tgtccattat ctgttaaatg gagaagaaat aattttatat
     8581 aatttcttgt ctcaaatgga attgtctgaa tataaagtag atgatgattg gcaacaaatg
     8641 aatgggacag ctttatttag tattaaatta aagaaagata tgttactttt gttggaacca
     8701 aacgatgcac ataaaacagg cctattggtt gaagaaccac ttaatattaa gaaagttgtt
     8761 tttaaggtaa aaatttaact gaaagtactt tcggggatta agaattttaa aatatttaag
     8821 aaattgtatt ctaaagttct aaaattatag atatttaatt taaagcttgt taaaatagaa
     8881 tagtaacact catctgcttt caaaaagcat tctagtccat ctccgattaa cgatggactt
     8941 tatcacctcc ttctccagtc cttgtatgac atcttgaagt tgattcatga catcttccaa
     9001 aattcgaaag gctttattct taaatccacg tttacgaatc tctttccaca cttgttcaat
     9061 ggggttcatc tctggtgtgt atggaggaat aaatgcaaaa ccaatattag tcggaatctt
     9121 taagatactt gatttatgcc atatagcatt gtccataacg agtaaaaaat aatcatctgg
     9181 ataagcttgt gaaagctctt ctaaaaagac gttcatccac tcagta
//
LOCUS       DAVHLA010000065         9172 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVHLA010000065 DAVHLA010000000
VERSION     DAVHLA010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9172)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9172)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9172
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.065"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(<1..743)
                     /locus_tag="VVO77_001964"
     CDS             complement(<1..743)
                     /locus_tag="VVO77_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEU5693924.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTTKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGFLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMT"
     gene            complement(758..1606)
                     /locus_tag="VVO77_001965"
     CDS             complement(758..1606)
                     /locus_tag="VVO77_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HEU5693925.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVPNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(1603..3078)
                     /locus_tag="VVO77_001966"
     CDS             complement(1603..3078)
                     /locus_tag="VVO77_001966"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HEU5693926.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(3401..4756)
                     /locus_tag="VVO77_001967"
     CDS             complement(3401..4756)
                     /locus_tag="VVO77_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU5693927.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWRAIILSVVCLIISVLTYFPFVKMAYKTEL
                     S"
     gene            complement(4766..5083)
                     /locus_tag="VVO77_001968"
     CDS             complement(4766..5083)
                     /locus_tag="VVO77_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU5693928.1"
                     /translation="MDESNLESVMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTREAQGEKTSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(5100..5417)
                     /locus_tag="VVO77_001969"
     CDS             complement(5100..5417)
                     /locus_tag="VVO77_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU5693929.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(5432..6328)
                     /locus_tag="VVO77_001970"
     CDS             complement(5432..6328)
                     /locus_tag="VVO77_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEU5693930.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(6331..7593)
                     /locus_tag="VVO77_001971"
     CDS             complement(6331..7593)
                     /locus_tag="VVO77_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU5693931.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDILLYLPFVIAIEKRFKLLED"
     gene            7873..9051
                     /locus_tag="VVO77_001972"
     CDS             7873..9051
                     /locus_tag="VVO77_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEU5693932.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALFYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
BASE COUNT         3196 a         1951 c         1293 g         2732 t
ORIGIN      
        1 gtcattccca tgacaaagaa taacatccct ttaaaacagt atcttaccca attttcaggt
       61 aagacttttg atacaaccgt ccccaatacc cctccgcata tagaagcaag aaaaataact
      121 ggaacaggtg ctaaatgata ctgatttaaa cctgtaacca caacaattgt agccaaatga
      181 gacaactggg aaaagaaaat aattgcaaga gaatacatcg ttgcttcttt tatcgaaata
      241 gaaaaaaaca ccatcaataa agatacattg agcggaccac caccaatccc taaaaaacta
      301 gaaatcaagc ccaatagaaa accacaaatc atatagaatc ctatcttatc aaattgataa
      361 gtttttttaa aatctgttaa aacaaatgat acaagtagca tcacaaatag taaaatcatt
      421 tgaacaatgg atactagccg tactgataat tgagataaca aaacttgaaa aataagatga
      481 cctagaaacc ctcctaaaac agaagaaaag gataccgtaa aaatcaatct ccattttatc
      541 tctttacttt gtgaaaatct tttggttgtt gaaataatcg ccattataaa aacagagaaa
      601 ctagaataaa aagcaatatc actgaccgaa tggtatccaa aactatccat aagtggctta
      661 attataattc caccacccat gcctgatata gaacccaatc cactagctat tataatgatt
      721 agaaaataaa taatctcaac cactttttaa gtccatccta ttctttcaaa catctaaaac
      781 ctagatggct actagtggaa gtagaaatac atccatttct agcagctact cggtatcgat
      841 tacaataaga acaatgacat aaaaaggaac ctcctctgat agcatactcc tcatcttgta
      901 tcccatattt tggcaactca tagtcatctt cattaaaact agctaataag gtatatctcg
      961 gattgcgaca ccattcccaa acattcccaa tcatttgata tagaccaaaa tcattaggta
     1021 aaaattcata gacaggagcc gttcctataa atccatctaa ggcagtattt tcataaggaa
     1081 atcttccttg ccaagtattg gcatgataat atccaccttc taaaagagta tctccccaag
     1141 gatattcaga ttgtcttcct cctctagcag catattccca ctgtgcttca gtcggtaaag
     1201 acattccgct ccaattacag aaagccaatg catcttctaa agcaacatga actactggat
     1261 ggtcttctaa acccactaga ttactattct caccgtaggg atgtttccag caagcgttcg
     1321 gaacttgtaa ccaccacgga gccccagcag gatgaggata tccctccctt tctgcctctg
     1381 gaacgaacaa tataaaaaca aaagaccact cttgtcgctc agctagtgtt ttatagcctg
     1441 tttctttcac aaattgagca aattcttgat tcgtaactgg agtatccgca atggaaaaat
     1501 cctttacact aacagcgact tgaggacctt caaaatcatc taaaaagccc tcttcagaat
     1561 ttgttcccat cataaatgtc ccacccttga tttttttcat tttcatgatt gactatcccc
     1621 cgttttcgtt agagttggcg ttattttaga aagttcaaca ggaactaact cttcatccac
     1681 aacaaaacct tcttctctat atctaagaaa gtctactaat tttttcttca tctgacgaac
     1741 aataggttgg tatttttcac ttggatacaa atcattcatt tcatgcggat cttttttcat
     1801 atcaaataac tgataatgat ttaaaacagg aaaccagata aatttccact ggtctgtcaa
     1861 gatatattga ctagaatctt ttcctaaagc atgttcacca tgaaattctg ttcgccaccc
     1921 ctcgtactgt ccaaataata aattcttaac actccgtcca tctagttcat ctgtagtagt
     1981 tcctcctgcc aaatccacga gtgaaggaaa aatatcttga attttcacta attgcttgat
     2041 tgttccccta ttaccagcta tcaatccagc cggatcgtaa ataaacgaag gaatgtggat
     2101 acttccctga taaggatatc cctttctaaa cagataatgt tcaccaagct gatctccatg
     2161 atccgaaaca aaccagataa tcgtatcttt atcatgacga aattctttta gggcagtcaa
     2221 aaagcgacta atttgatggt ctatatgagt aatcaatcca aaataagcag caaccattct
     2281 tctttgatca tcttccttta atttccctct taaagcataa atagacggaa tttgcttttc
     2341 taatacttcc caattcccga tatgcaaatc gagaaattga ggcaagcgtt ccatatacat
     2401 atcaaaatag tattttgggg gatttaatgg agcatgtggt ttttcaaaag acattttgag
     2461 aaaaaaagga accgttggat ctcttctttg taaaaatgaa atggactcac tcacaaccca
     2521 gtttgttgga tgtaacttct catctttatc ccaaggtcta gcttcccaag aattacaatc
     2581 cattccgtca tcaatcaaat caacatcata accaacttta ccctttaaaa aggctagata
     2641 gtcactagca taatcaaatt gacttccata agccttatca tactttctat caacatgtag
     2701 atacccatcg tgaagtaaga catgatcaaa cccaagtctc tgtctggaag gaaaaacatg
     2761 catcttacca atacactctg tttgataacc catatcttta aagacttttg gaagagtatt
     2821 agtaaaattc caaggcacct catcttgata accaactcgt ccacttttat cttggtctaa
     2881 gccagtcaat aaagctgccc tagcaggaac gcaagaagga actggagaat aggcattttc
     2941 aaaattataa cctacactag ccatcatatc taatgttgga gtgctaacta gcttatcctt
     3001 actattcaag gataaggcgt ctgctctcat ttgatctaca acaatcaaaa taatatttgg
     3061 ctgttttgtc tgaaccataa aatctccttt ctaatatggc aaaagaggca caagaagata
     3121 tctaccttta ctgcacccct ttctatatca atctctctat ataaaacaat aacattcttg
     3181 ttatgtttta tagaaaaatg aactaaaata tgactaaatc gattaggaaa ttcaaatcat
     3241 tttctagtac tgttttagaa gttacagtgt actattccaa cttcaataaa ctataaacct
     3301 ttgtctaata acaattttag tggagataag aaatcctaca cctaactcat cttacacgta
     3361 atctatttct attttatcac aaaaaacgca agtaagacca ttaactcaat tcagttttat
     3421 atgccatttt cacaaatggg aaataagtca agacactaat aatcaaacaa acaactgata
     3481 agatgatggc acgccaatca aatgctgtag agaagaaacc atataaaatt ggaggcatta
     3541 cccaagtaac gttttgtgta acaggtgaaa caagacccca gcttgttgcc cagtaagcta
     3601 ccgttgccat gaaaaccgga ctaagtacaa atggtataaa tagcaaagga ttcaagacaa
     3661 ctggtaaacc ataattgacc ggctcaccaa tattaaacag aactggtgct agaccaagtt
     3721 tagcaacttt tcgataatga ctgtttcttg aaaaaattaa aatagcaagt actaatccta
     3781 atcctccaaa ccagacaaac gccccaaaag acccacttgt ccatatataa ggaatcggtt
     3841 cacctttttg gaaagcatcc agattcgcta acatagcaac tccaaacagc ccttccatga
     3901 tgggagccaa tacatttcct ccatggagac caaaaaacca gaataactta ttcaaaaaga
     3961 tcatcagaat aactgcaaag aaactttgag acaaacctag taatggcgtt tgtaacacct
     4021 tgtaaaccca atcaatcaat aagtcattgc taagtaaatg gaaaacataa gtcaagatgg
     4081 ctactatata catcgccata aatcctggaa tgatagaagt gaacggctta gcaatcgcag
     4141 ggggaactga atctggtaac ttgattaccc agttcttttt cattacttta cagaaaataa
     4201 tagaggctaa aaatccaatc atcatggctg taaagtagcc tctggcatta atatggtttc
     4261 ctggaatcac attcccaata gttaccatca gatttttacc atcaaatgct agattatcaa
     4321 ttccttgtaa gatttgatct aatttcacat ctcctacatt tgccaaaggg aaactctttg
     4381 taactgtact tccaatcgaa atgacaaacg aagcaagtga taccaaacca gcagaaactg
     4441 tatcaacctt gtaaatctta gcgatattca ctcccaagca atagatgaac aacaaggaaa
     4501 caattggtat acttcccttg aataccaaat tattgatgtc aacaagccac tgaaaggttt
     4561 tcgtaatact ttctaggtga aattgttgtg gtaaatccac tagaaaagca tttaataaca
     4621 aagcaatgga acctgtcata ataacaggca tagtccccac aaatgaatca cgtaaagcaa
     4681 ctaaaaactt ctgattccca actttcattg caattggaga aagtttttct tgcattttat
     4741 ccaacattgt attcatacca aactcctaat ttttttcaaa tcgttcgtat acttctacca
     4801 cttctttcgc caagtcaaca aaagtcagac tcgtcattaa atgatcttgc gcgtgtacca
     4861 tcaagaggct aattgatgtt ttttccccct gtgcctctct tgtcaacatt tctgtttgag
     4921 ccttatgcgc ctgtaataag gcagcattcg catcagctaa tcttcgattg gctttagaga
     4981 aatccccttt ttttgctgcc tgaatagcct ccatagcatt acttttggct tccccaccat
     5041 acataattag ccccattaca gattctaaat tactttcatc cataacattc tcctcaatct
     5101 tagtctaata aactttcagc taaatctaaa actttagaac cattcatcat tccgtaatct
     5161 gtcatcggaa taaccgccac aggaatctgt ctatctttta gtttttcttg aaagtcccct
     5221 agtaaatagc gaacttgagg acctaaaagc aacacattta cttcttttgt tgctacaatt
     5281 tcttctgctt caggagctgg aactgcaaaa atttctgcat ccaacccctt atcttctgct
     5341 gccttttgca tctttgtcac tagcagactt gtactcatac ctgctgcaca tgctaacata
     5401 attgttactt tagccatagc ttactccttt atcacctatt tactgaccta gccaagcgag
     5461 atactgtatg tctcactcct ctaattgcct tgctcaatgc ataaatatta tcgactgttg
     5521 ccagtccccc atatcctgcg tcacctatat gttgaatatc aactccacaa attttatttc
     5581 taagtgcaat ttccttgata gtatctgtat cagatgtttc ttggctagta ccaatagcac
     5641 tcaatacaag accaccctta ctatgaacga gatcaacgac ttcacgcaac tcttggtcat
     5701 gaaaggctgg aacggttcca actgctggaa caagtatcac atccgcacct gcttccaaca
     5761 attgctctgc gacagaaagc tctgccacag gctcattcac tcctgccccg tgcatcttac
     5821 ctgcaataat caaaccagaa aagttttcct tagcagtttg aacagcctta atgatttctc
     5881 gattgctaac tcctgttcca ggatttccag tcaaacagac aaagtcaaaa cctaactcct
     5941 ctattcgatt caatgtttca acactagcaa cacgacctgc aacaatttcc tgtgtttcct
     6001 ctagcatctt tgcagatggg tcaatcggtt ccaaatttac accaattgga caagcaacaa
     6061 gctggtgtaa gcgatgaata acatcatcac ctgaactatc caaagcataa attttaggct
     6121 caaaaacatc aacacaattc aataaaatca tatcagctcc aaaagctcta gcaatttcag
     6181 aattagttat atccccaaca aatgtctcac gagtaactac attttcagat agaacaactc
     6241 taccttcact tgctaaaata ctttgtttta attcttcagc attcatctgt aatatctcag
     6301 atggatttgc actaattaaa cgtttcattc tcaatcctcc aataacttaa atcgtttttc
     6361 aatagctatt acaaatggta aataaagtaa gatatccaaa acaatcaata caatttgtag
     6421 taatgaacca gaaatacttc ctgtagcaag taaaccactt ataacaggtg gcatagtcca
     6481 acctggatct gtataagtta gcggaaccaa acctgatgcc attgctcccc acgctactag
     6541 taagttaaac attggagcta agataaatgg aactagtaac aaaatgttca aaacaatagg
     6601 aacgccaaac attgctggtt catttatatt aaataatcca ggtataacag ttataggtgc
     6661 caaagttttt agttgtttac tagctttctt cttatgtgct aaatatccta acgcaagaac
     6721 taaacctatg gttgcaccac cgccacctat gaatacaaaa ttatccataa atacgctagt
     6781 aaaaatattt ggaagagttt ctccagtttg ataagctact ttatttgcat ctagattagc
     6841 taaccataac ggtttcataa ctgcattaac aacatttcct ccgtgtaatc ctacaaacca
     6901 aaaactacta ttaaggaaaa ttaagataag aagaccaata acattatttc ctaaaagtcc
     6961 aagtggacct cccaaagcta cttgagcaat ttcatgaaga ttaggtaaac ttaatttatc
     7021 taaagttgca taaacaatca accaaccaac aatagtcact gcaccaggaa taatggcact
     7081 aaagctttta gatactgctg gtggaacacc atccggcatt tttatctgta tattatgatt
     7141 tataaaccat tggtagatat agccattaat caatcctaaa atcatagcaa caaataaacc
     7201 ttttgatgcc atgaaagcgg taggcattcc tgctccagcc tctcctctaa tgaaaggcgt
     7261 aactgtaata aaagatgata atgacacaat accagcagga ataccatcaa ctttgtattg
     7321 tctagccata aagtaagcga taccaaaact agctacaaga ccaagtaatc caaaactact
     7381 atcaacaccc ttccataaat agtcagcaac accaatatca cccagatatt tttcccatcc
     7441 tggaatagga aaacttgcaa taaccattag taatgaacct atcaacaata aaggtatagt
     7501 tagagtaata ccgtctcgaa tagaaaccaa cgctttatta ttacccaatc tagccgctac
     7561 tggaagtaac ttttcttgta ataatttttc cataaccttt tcctcttaaa tatattttat
     7621 tatcaaaagt tatcaattat ctttattttt tgacgtcaag ttgttatttg attatctttt
     7681 gttatttata ttttacaact ataagaaagc cttgtcaagg atttgtgtaa acatttgatt
     7741 attttttatt atcaatatat aataaaaaga gaccagtaag taatgaaaag cttaaaaaga
     7801 ttaacatcta catttatcca tagcaaaaaa tcataggatt ttaagaatct gacaactagg
     7861 aagaaaacta atatgacctt atctaagaaa caattacaac taagagctaa aatactggaa
     7921 acagtttaca cattaggtcc catttcacga attgaaatcg ctactaaaac aggaataaca
     7981 cctgcaacaa ctagcagtat cacaaatgat ctgattaaag aaaatattct cttagaactt
     8041 ggtgaagacg aacacgatac aagcgtaggg agaaaaaaaa tcctgctaga cattcaagct
     8101 aaacgatttt actacattgg ttgtgaacta tctgaaaaac atttcacttt tgctttagga
     8161 gataatctag gaaatatctt aaaggaagag aaagaaattg ttactaaaca gttaatccaa
     8221 gaaaagggaa atcaactcat taaccagaca ctaaagcaat tcttaaataa ctgctctgat
     8281 tatgaaatag aagcaattgg aatcgcgcta cctggtcgct atttagatga ttataaaata
     8341 acaacaaaca atcctttatg gcaacatatc gacttagaaa tgattcaatc ccactttgat
     8401 aagcctttgt ttttctctaa caatgttaac tgtatggcta taggtaaacg cctatttagt
     8461 cgccaacaga atgaccctaa ttttgcttat tttcattttg ctagaggtat gcactgttct
     8521 tatatctacg acggaaacat ttatgggaaa ggaaatctaa tgattggaga aatagggcat
     8581 acagttgttt catctgaggg agaagaatgt agctgcgggc gcaagggatg cttacaaact
     8641 tttgctggag aatcttggtt aatcaaaaaa tcaaaaattc tatatcatca atctccctat
     8701 tctctacttc ctagtttagt caaaaatgcc gatgatattg atatccaagt tattttaacc
     8761 gcttatcaat taggtgacac tggaataatc acacttatcc atcaagcctt attctatctt
     8821 agtcaaacca ttttaaatat cagtatgatg attgactctc aaaaaatcta cctacatagt
     8881 cctttactaa caaatcaaca catcatccaa aaactatata gtgaaatgaa ctacaaaccc
     8941 aaactgctct ataatcgcct acctgaagtc attattgaac cttacaatga ttttacagcc
     9001 gcacactcag ctattgcact ttgtttgtat catacaattc tacattctta attttctatt
     9061 acatttaata aataggctaa aaagagggag tatatcataa aaagcgaata aacctgtttt
     9121 ctgaaaatca gaattctgtt ttgttcgctt tctttatatt tggaattata ct
//
LOCUS       DAVHLA010000066         8961 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVHLA010000066 DAVHLA010000000
VERSION     DAVHLA010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8961)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8961)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8961
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.066"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(52..1464)
                     /gene="sufB"
                     /locus_tag="VVO77_001973"
     CDS             complement(52..1464)
                     /gene="sufB"
                     /locus_tag="VVO77_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEU5693933.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVICELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(1518..1958)
                     /locus_tag="VVO77_001974"
     CDS             complement(1518..1958)
                     /locus_tag="VVO77_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEU5693934.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            complement(1945..3171)
                     /locus_tag="VVO77_001975"
     CDS             complement(1945..3171)
                     /locus_tag="VVO77_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU5693935.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAIEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPAIARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            complement(3182..4444)
                     /gene="sufD"
                     /locus_tag="VVO77_001976"
     CDS             complement(3182..4444)
                     /gene="sufD"
                     /locus_tag="VVO77_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEU5693936.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKINYLERLESRGEGSAKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            complement(4472..5242)
                     /gene="sufC"
                     /locus_tag="VVO77_001977"
     CDS             complement(4472..5242)
                     /gene="sufC"
                     /locus_tag="VVO77_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEU5693937.1"
                     /translation="MSVIEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            complement(5392..5586)
                     /locus_tag="VVO77_001978"
     CDS             complement(5392..5586)
                     /locus_tag="VVO77_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEU5693938.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            complement(5614..7269)
                     /gene="dnaX"
                     /locus_tag="VVO77_001979"
     CDS             complement(5614..7269)
                     /gene="dnaX"
                     /locus_tag="VVO77_001979"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEU5693939.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVNLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNAGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLAGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            complement(7269..7766)
                     /locus_tag="VVO77_001980"
     CDS             complement(7269..7766)
                     /locus_tag="VVO77_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEU5693940.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            7960..>8961
                     /locus_tag="VVO77_001981"
     CDS             7960..>8961
                     /locus_tag="VVO77_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEU5693941.1"
                     /translation="MEQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYDAPSCP
                     DCGSLMKKYDFQKPSKIPYLETTGMPSRILLRKRRFKCYHCSKMMVAETPLVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLAISTSTVIRKLNDFHFEHDFSRLPKIMSWDEYA
                     FTKGKMSFIAQDFDNLNIITVLEGRTQAVIRNHFLRYDRAVRCQVKIITMDMFSPYYD
                     LAKQLFPCAKIVLDRFHIIQHLSRAMSRFRVQIMNQFERKSHEYKAIKRYWKLIQQDS
                     RKLSDKRFYRPTFRIHLTNKEILDKILSYSEDLKHHYQIYQLLLFHFQNKDPEKFFGL
                     "
BASE COUNT         2621 a         2018 c         1646 g         2676 t
ORIGIN      
        1 ggcgatgctg acgtggtttg aagagatttt cgaagagcat aaaatcaaat tttatccaac
       61 tgatccctcc atttcatagc taatcaagcg gttcagctca actgcgtatt ccattggaag
      121 ttcttttgta aagggttcta caaatcccat gacaatcatt tcagttgcct cagattctga
      181 caatccacgg ctcatgagat aatacaattg ctcttctgaa atcttagata ctttggcttc
      241 gtgttccaaa gccacttgcg agttgtgaat ttcattaaat ggaatagtat ctgatgctga
      301 caagtcatcc atgataatgg tatcacattc aatgtgggaa acagatttct tagagttctt
      361 gttaaaggtg acttgtccac ggtagtcaac ctttcctcca cctttagcga tggatttaga
      421 cacaatagac gagctggtat gtggagcatt gtgaatcatc ttagcacccg tgtcttggtg
      481 ttgccctgca ttagcaaagg cgatagagag catggtacca cgcgctcctt ctccatcaag
      541 gtaaacagat ggatatttca tagtcgtttt ggcacccaag tttccatcaa tccactcaac
      601 agtggcatcc ttttgagcct tagcacgctt tgttaccaag ttatagacgt tatcagacca
      661 gttttggata gttgtataac gcatataagc tccgtccaaa gcaaaaattt ctacaatggc
      721 agcgtgtaag ctattgcttg aatatgttgg tgctgtacat ccttctacgt agtggacgct
      781 tgctccctca tcaacgataa tcaaggtacg ttcgaactga cctatatttt cgttattgat
      841 acggaaataa gtttgaagtg gaatatctac cttgacacct tttggcacgt agataaaagt
      901 tccacccgac catactgctg agttgagggc tgccaacttg ttatctgtcg gcggtaccaa
      961 cttcgcaaag tattgtttaa ataagtctgg gtattccttg agtgcggaat ctgtatctgt
     1021 aaagataata cctaattttt ggaactcttc cttcatgttg tggtaaacca cttctgactc
     1081 gtactgggca gaagcccctg ctaaataagc acgttcagct tctggaatcc cgatacgttc
     1141 aaaggtttct ttaatctttt caggtacatc atcccaagaa cgggctggtt tgtcagatgg
     1201 tttttggtag tagattaagt catcaaagtc aatctctgac aagtctgctc cccaagtttg
     1261 catgggcatt tttttgaagg tttcataaga cttcaaacgg aactccaaca tccactcagg
     1321 ctcaccctta gcagcagata attcacaaat aacaccttcg ttgagtcctt ttcctgtcga
     1381 taagacaggc tctacatcgt catggaaacc aaatttatat tcaccaaggt caattggttt
     1441 tggttctact ctttcttcag ccataatatc ctttctttct tcatttctaa taattcataa
     1501 gacaaaagaa acttgtctta ctgtttttct tgattttcaa ttgttttctt aagggcattc
     1561 caagctaggg ttgcacactt gattctttga gggaatttgg caacacctga caagaatgcc
     1621 gcgtctccaa gttggtcttg acgctcatct ttttgccctt gaaccatttc agaaaaaata
     1681 gtcgccagtt ctaaaatttc ttgtttggtt tttcctaaaa cggcatctgt catcatacta
     1741 gcagaagcag ttgaaatcgt gcatcctgaa tttagaaaag caatatcttc caaacggtcc
     1801 tctgcatcaa acttgacaga gaggttgatg acatccccac aagtcggatt gttgagactg
     1861 atttgctcag cgtcttctaa cttcccttgg tgatgtggat ttttcgaatg gtctgctacc
     1921 actgccatat aaaggctatc tagtttagaa agtgccattg aaaaactcct ttgtcttttg
     1981 tagggcatcg actagtttgt cgcaatctgc cttggtattg tagatataaa aacttgcacg
     2041 agctattgct gggacttcca aatactgaag caagggttgc gcacaatggt gaccagcacg
     2101 aacagccact ccttcataat ccagagccgt cgcaagatcg tgaggatgga gatcacctag
     2161 gttaaaggca ataacacccg aacgttgagc caaatcctga gaaccgtaaa tggtcaatcc
     2221 ctcaattgcc tgcagttttg gatagacgta cgcaatcaat tcctgttcat gagcttcaat
     2281 ggcatccata ccaatctttt ccagataatc aactgcagtc gcaagtccaa tagctcctgc
     2341 catatttggc gttccagcct caaatttcca aggcaattcc ttccaactag cagattgctc
     2401 gtagacaaaa tcaatcatct cgccgccaaa ttctactgga gacatttgct caagatactt
     2461 ttctttgccg taaaggacac cgataccagt cggaccagcc atcttgtgac ccgaaaaggc
     2521 gaaaaagtcc agatccaagt cctggacatc aatcttcata tgaggtgtag attgagcacc
     2581 atccactacc atgattgccc caacttggtg ggctaattga gtgatttcct tgatcggatt
     2641 gaccacacca agaacattgg aggcatgagc tagggaaaca aatttaacct tatcagtcaa
     2701 tttagctcgc aaatcctcca tatccaaggc accgtcttta agatagacat agacaagctc
     2761 tgctccagtc tttcgacaag cttcctgcca tggaatgata ttagaatggt gttccattac
     2821 tgaaatcaag acctggtctc cctcagtgag aatttcctca gcaaagcgtg ccacccagtt
     2881 aaggctggtt gtcgttcctc tggtaaagag aacttccttt gtagagcctg cattaataaa
     2941 cttacgaatg gtttcacgag cagcttcata agaagctgtc gctcgttccg ctaaggtatg
     3001 gacaccacgg tgaacattgg cattgtcctg ctcatagtag ctgttaatag ctttcagaac
     3061 tactagtggt ttttgtgtcg tcgcagcatt gtccagatag accagaggtt catcattgac
     3121 aatctgatct aaaattggaa aatccttgcg aatcgcttct acatctaaca taggctgccc
     3181 cttagcgttt tgacaatttc tcttcgatag ttgcaatcat ttcatcacga acttccttga
     3241 ctggaatctc cacgataaca gatccaagga aaccacgaac aaccaaacgc tctgcagttg
     3301 ccttatccaa tccacgactc atgaggtaat acatgtcttc tggatcaact tgtccgatag
     3361 acgctgcgtg tcctgcagtg acatcatttt catcaatcaa aagaattggg ttagcatctg
     3421 aacgcgcttg gtctgaaagc atgagaacac ggctctcttg ttgggcatct gctcccttag
     3481 cacccttgat gatgtggccg ataccattga aagtcaaagt tgctttttca aggataaccc
     3541 catgttgtag gatatttccg atagagttgc agccatagtt agttacacga gtatcaatcc
     3601 cttgtacctg acgaccactt gaaagagcta caaccttgag gtcagcatgg ctaccattac
     3661 caatcaagtc actatcaaaa tcagcaacga catttccttc gttcatgaca ccgatagccc
     3721 agtcaatact tgcatcgttg cctaatttac cacgacggct aatgtaggca gtgacgtttt
     3781 cacctagtcg gtcgatagca gcaaacttga cttgcgcacc tgaacgtgca atcacttcta
     3841 ctgtgatatt agcagttgct ttggcacttc cttcaccgcg tgactctaaa cgctccagat
     3901 aattaatctt agaattttta ccagcgataa tcataatatg cttgttaaac ggcacattgc
     3961 tatcgctatc ttggtagaaa attccttcaa ttggctctgt gatttctacg ttatctggaa
     4021 tatagagtac agcaccactg ttaaagtaag ctgtgtggta agccgccaac ttgtcatcat
     4081 catacttaac agatgacatg aagaattctt cgatcagctc tggaatttct tctaaagctg
     4141 agtgaaagtc tgtgaagaca acaccctgtt cagctaactc aactggagtt tgttcgaaaa
     4201 cagtttgagt tcctacttgc accaacttca agtgatgatc taaagctgtg aaatctggaa
     4261 catttgctga tggctcattt tctgtaatcg ttccatcacc cagattccaa cggtggaatt
     4321 tgacacgctc aataactggt aattccaaag tctcaatctt gtcaaaagct ttttgacgga
     4381 gatcagccaa ccagcttggt tcagcgtgca tttctgaaaa aagtttaata ttttctctag
     4441 tcatttactt ctcctaaaag atacgaggga attacaattc ttccttgtag tcgtagccaa
     4501 gttcttcagc taattttgcg tatccttcac gttccaaacg cgcagccaat tctggaccac
     4561 cagaaaggac aacacgacct tccatcatca cgtgtaccac atcaggtgtg atatagttca
     4621 aaagacgttg gtagtgagtg atgatcatag caccaaaacc ttcaccacgc atggcattga
     4681 cacctttaga cacaacttta agagcgtcaa tatcaagacc tgagtcaatc tcgtccaaaa
     4741 gagcaaatgt tggctccaac atcaaaagtt gaagaatttc attgcgtttt ttctcaccac
     4801 cagagaagcc ttcgttgagg taacgctctg ccatttcttc tttcatgtta agcaattcca
     4861 ttttttcatc tagcttagta ataaactcac gaactgaaat cttctcatca tcttctttac
     4921 ccgcattcat agcggcacga agaaattcag cattggtaat tccagggatt tctgatgggt
     4981 attgcatagc aaggaaaagt cccatacgcg cacgctcatc cacttccaac tcaaggatgt
     5041 ttacgccatc aaacaaaact tcacctttag ttacttcata gtttggattt cccatgatag
     5101 cggcagaaag agtcgattta cctgtaccat ttggtcccat gatagcggca atttctcctg
     5161 ttttcagggt caggttaacc ccttttaaaa tttcttttcc ttcaatctca acgtgaagat
     5221 ctttgatctc tattactgac atgatagttc ctttcttttt caaaactttt acagtactta
     5281 ctagaaaaac gtctgatttc cccagaaata gagcaaaaat tctataaata tacttttcta
     5341 gtataacaaa aaaaagccta aaaggctttg attttgtctg gaagctgagg gctagtcttt
     5401 cctattaaaa tgctgatcga tgacatcaac gattttaccc atcacataac tgactcggaa
     5461 atttctaaag agtaaaattg cccaaaaggc tgccataata tagcggccag tcatccaggc
     5521 ttcattgaaa aaataggtct cagcagctgt aaatagcgcc ataataataa attgttgttt
     5581 attcataaac ttattgtatc atgaaatctt tctttagtct tcctctacct tcactttatc
     5641 agccaaaaat tcaaatcctt ctggaatcag gctttcttct acttcttttt cagtttgaga
     5701 agatttggct ttggctgaaa aggctgcgcg aacttctttc cattcctcca tggaaatagc
     5761 taaaatctca ggtgaaaaac ctgccgcctg actgaggata ttaccaaaca tggtattgag
     5821 attgtctcgt ttcatagttt gaccagcatt gaagttagac tcaaaagcaa gaatagcatg
     5881 gtgttcattg gcagcaaccg gttgagaacc agctagcaga gccttgtccg gcccacctag
     5941 actttcaatt acctctcccc aggcattctg caaacgaatt aaattttgac gtgctaaatc
     6001 aggattttcg acggcctctt gtaagataga ttgcacttta ttgcgatcga cacgatagac
     6061 tgttttgccc gtagctggtc gactaggagc tggtgcaact tgtttaggaa ccgcacctgc
     6121 attagaaagc tcttgtttga gacgggcaac ttcctgtctc agcgtagcaa tttcattttc
     6181 aaccgctcct gatagagctg gttcgggctt gatttccgcc aaacggacgg tcatcatttc
     6241 agcataaatc ttgggctgca aactagactt aatatctgct aaattcactg ttgctaagcg
     6301 aatcatttca aacagatttt tttgaggaag tgccaaattt tctacaaaga ctgaactatg
     6361 atgagtattt tctccccctg tttgaacaat taacaagtct cttaaatagt gcaaaagatc
     6421 ggtcacaaaa cgagtcatgc tcttaccatt gtcaaaaaga agattcaagc aagacaaagc
     6481 tttgggaaca tcctgttgag acaaggccgc cacataatca tccaaggctg ataggctaat
     6541 ggtgccagta atttcttcag agatagcagt cgtcagctca tttccctgtg tcaaactcag
     6601 ggcttgatcc aaaatagaca aggcgtcccg cattccacct tccgcccgtc tggcaatgat
     6661 ttccacagcc tctggttcag aactgatatt ttctttttct aagatatagt gaatatgttc
     6721 cttaatatcc tgtgtcttaa ttgatttaaa ctcaaaacgt tgcacacggg atagaatagt
     6781 agcaggaatc ttgtgcaatt cagtagtggc caaaataaag actacattct gtgttggttc
     6841 ttccaacgtc tttaggaggg cattaaaagc ccctgtagac agcatgtgaa cctcatctat
     6901 gatataaacc ttataacgag caaggctagg cgcataggta gatttatcac gaatttcgcg
     6961 aatttcatct accccattat tagaagctgc atccatttca atgacatctt ctaaactacc
     7021 gtccgtcact gcttgacaaa tatagcagtt attgcaaggt tcgccaccca cttgattggg
     7081 acagttcata gccttggcaa agattttagc aacactggtt tttcccgttc cacgaggacc
     7141 agaaaaaaga taagcgtgac ttattttctc ttgctccacc gcttgtttaa gagtcttagc
     7201 cacaacttct tgaccaacta actgggagaa gttttgactt ctatattttc gataaagtgc
     7261 ttgatacatt aagatttttc ctcaaacatc gtaaagtccc atgttgtctt ttcaagcaaa
     7321 atagcgacaa attgttccaa ataatctcga tccatagcat cgtaatcctc aatctctgaa
     7381 gaatccagat ccagaactcc aagtaactga ccattcttca tcatcggcac cacaatttca
     7441 cttttagcta gactatcaca agaaatatag ttgagatagg tcgtcacatc tccaacaata
     7501 acagtttcct gaaagtgagc tgcctcacca caaaccccct tgcctagtgc aatacggatg
     7561 caggaaacac ctccttggaa ggggcctaaa accaattcct ttccatcgaa caaataaaag
     7621 cctgcaaata cggtattagg aaaacgtgat tttatgagag cactggcgtt ggaaagatta
     7681 gccaaaacat tggtttcgcc ttccaatagg aaggacaatt cttcatttaa catttgataa
     7741 cgtgattgtt tttctgattt taacatagaa ctattatatc aaaaaaggag cagagacaaa
     7801 agaaaaatcc cttgtttagt aaacaaagga ttttggactc tataatattt gtagtgggta
     7861 aatccactat agatattatg gagcctattt ttgtgtagaa aaaaagtccc atatgaccta
     7921 taatgaaaag cgacaaaaca actcattaga aagaatcata tggaacaatt acattttatc
     7981 acaaaattac tagacattaa agaccctaat atccagattt tagacatcat caataaagat
     8041 acacacaagg aaatcatcgc caaactggac tacgacgccc catcttgccc tgattgtgga
     8101 agtctaatga agaaatatga ctttcaaaaa ccgtctaaga tcccttacct cgaaacaact
     8161 ggtatgcctt ctagaattct ccttagaaaa cgccgtttca agtgctatca ctgttcaaaa
     8221 atgatggttg ctgagactcc cctggtaaag aaaaatcacc aaatccctcg tatcatcaac
     8281 caaaaaattg ctcaaaagtt aattgaaaaa atttctatga ctgatattgc ccatcagctg
     8341 gccatttcaa cttcaactgt cattcgcaag ctcaatgact ttcactttga gcatgatttt
     8401 tctcggcttc caaagattat gtcttgggat gagtatgcct tcactaaggg aaagatgagt
     8461 ttcattgcgc aagattttga taatcttaat attatcactg ttcttgaagg cagaacacaa
     8521 gctgtcatcc gaaatcactt tcttcgctac gatagagccg ttcgttgtca agtgaaaatc
     8581 attacgatgg atatgtttag tccttactat gacttggcta aacagctttt tccgtgtgct
     8641 aaaatcgttc tagatcgttt ccatattatc caacatctca gccgtgccat gagtcgtttt
     8701 cgtgttcaaa ttatgaatca gtttgaacga aaatctcatg aatacaaggc tatcaagcgt
     8761 tactggaaac tcatccaaca ggatagtcgt aaactcagcg ataaacgttt ttatcgccct
     8821 acttttcgca tacacttaac aaataaagaa attcttgaca agattttaag ctattcagaa
     8881 gacttgaaac accactatca gatctatcaa ctcttacttt ttcactttca gaacaaagac
     8941 cctgagaaat ttttcggact c
//
LOCUS       DAVHLA010000067         8695 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVHLA010000067 DAVHLA010000000
VERSION     DAVHLA010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8695
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.067"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(<1..1354)
                     /gene="rlmD"
                     /locus_tag="VVO77_001982"
     CDS             complement(<1..1354)
                     /gene="rlmD"
                     /locus_tag="VVO77_001982"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEU5693942.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
     gene            1392..2168
                     /gene="recX"
                     /locus_tag="VVO77_001983"
     CDS             1392..2168
                     /gene="recX"
                     /locus_tag="VVO77_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEU5693943.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINANQVSGDKGPYVLTQKLAQKGISKSTIEEILNDFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYFDAKIAFDELDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            2257..2790
                     /locus_tag="VVO77_001984"
     CDS             2257..2790
                     /locus_tag="VVO77_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEU5693944.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(3148..3633)
                     /locus_tag="VVO77_001985"
                     /pseudo
     CDS             complement(3148..3633)
                     /locus_tag="VVO77_001985"
                     /inference="COORDINATES: protein motif:HMM:TIGR01716.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
     gene            complement(3671..4003)
                     /locus_tag="VVO77_001986"
     CDS             complement(3671..4003)
                     /locus_tag="VVO77_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU5693945.1"
                     /translation="MKNYGEAFRYFRKLNGYSLEYAAADSISKSQLSRFERGENEISL
                     STFFELLSNINVSIENFCNHLEHYKRSERDDFLVNLSPNFYSLNIKGLEVIKNKQQKL
                     FEKSGKNS"
     gene            complement(4016..4789)
                     /locus_tag="VVO77_001987"
     CDS             complement(4016..4789)
                     /locus_tag="VVO77_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU5693946.1"
                     /translation="MIDKVIEQYKSHDNLDIRVELHKKYSKNKLGFNNWIFSNYQITD
                     EVKVLELGCGTGELWKSNSDSIDKMKQLIVTDFSKDMVKSTKSVIGNRNNVNYEIMDI
                     QKISFENETFDIVIANMLLHHVNDIPKALSEVNRVLKTGGIFYCATFGENGVVNYLAN
                     LFKDEVNQDLENRTFTLQNGKRYLSRYFNSVDTLLYDDELQVTSIDDLVKYIQSFKGI
                     SEIGSLEEEIIRKRLESEFNNGMLIIPKEYGMFIARKES"
     gene            complement(5236..5991)
                     /locus_tag="VVO77_001988"
                     /pseudo
     CDS             complement(5236..5991)
                     /locus_tag="VVO77_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            complement(6129..7751)
                     /gene="groL"
                     /locus_tag="VVO77_001989"
     CDS             complement(6129..7751)
                     /gene="groL"
                     /locus_tag="VVO77_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEU5693947.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(7767..8051)
                     /gene="groES"
                     /locus_tag="VVO77_001990"
     CDS             complement(7767..8051)
                     /gene="groES"
                     /locus_tag="VVO77_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEU5693948.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(8321..>8695)
                     /locus_tag="VVO77_001991"
     CDS             complement(8321..>8695)
                     /locus_tag="VVO77_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEU5693949.1"
                     /translation="IGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGEREADFVNM
                     VLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLLESRAQRA
                     MRENNAGQDLADLVLEEEELPF"
BASE COUNT         2652 a         1720 c         1456 g         2867 t
ORIGIN      
        1 aaactttttt tattaatttt acaacagctt cagttcgagc tgtatgtggg aacatatcga
       61 ccgactggat ataatgaaga tcatagactt ctactaagcg taccaaatca cgagccaagg
      121 tcgaaacatt acaagaaata taaaccattt tttctggtac ataagtaaga atagtatcta
      181 ataacttatc atccagacct gtacgtggtg ggtcaacaat caaagcatct gctcggtagc
      241 cttccttgta ccaacgagga ataatctctt ctgccgttcc agcttcataa tgagtattgt
      301 caaatcccat tcttttagca tttcgcttgg catcttcaat agcttctgga ataatatcca
      361 tacctctgag tgtttttact ttctttgcaa aggcaaatcc aatcgttcca actccacaat
      421 aagcgtcaat caaatggtct tctttatcaa catccagcgc ttttactgct tcgctataga
      481 ggacttctgt ttgctcagga tttagttgat aaaaagctcg aggggatagt gaaaattcat
      541 aattgagtac accttcttga atactctctt gcccccagat aatctctgtc ttttcaccat
      601 atatctcact ggttttagct gtatttgtat taacagctac tgtcacaact tctgggaaat
      661 ctttaaccaa ctcttttacc aattgagtta aattaagctg gcggtttgta acaataataa
      721 tctgaacctg tccggtcttt ctcgcgcgtc ggaccataat agtacggaca cctagaactt
      781 ttctctcatc cgtgattgga atctggtgat aagtaagtaa ttctgctaag cgattagcaa
      841 tcacttgggt ttccttatct tgtaccaggc agtctttcaa ctctactaaa tagtgagagt
      901 tttgtgcata taagcccgcc ttgacctgat ttttaaattt tcgagtctga aattgtaact
      961 tagctctgta atattttggt tcctgcattc caatagttgg acgaatttca taattttcat
     1021 atccggcagg agcaaatttt ttcagcgctt gatgaagtaa gtccgtcttg aactccagct
     1081 gcttatcata atgcaggtgc atgatttggc agcctccgca ttcattataa atagtacaag
     1141 atggcacaat tcgaaattta gacttcttgt tgaccttcag taattttgct tcaacaaagt
     1201 tgcgtctaat agaagtaatc tgacaataga tatcttcgcc tttgagagct ccaggtacaa
     1261 agactaatgt tttttggtaa aagccgattc cctcaccgtt aattcccatg cgcttgattt
     1321 ttaatggtat tttttgtttc actttcagat tcatacccct atcttatcac attttgagtt
     1381 ataatagagc tatgaaaatc acaaaacttg aaaagaaaaa aagactctat ctgatggagc
     1441 ttgataatgg cgacaaatgc tatatcaccg aagatacaat tgttcgtttt atgttatcga
     1501 gagataaggt gataagcgaa gaggaattga aagagattca agactttgct caattttctt
     1561 atggtaagaa tctggccctc taccacttat cctttaaagc acgcactgaa aaagaagtca
     1621 gagaatatct gaaaaaatac gatattgata aaaacatcgt ttctcaagtt attgctaatc
     1681 ttaaagaaga taagtggatt aatgatggtc agtacgctta tgctatcatc aatgccaatc
     1741 aagtttcagg agacaaggga ccttatgtac tgactcagaa attagcacaa aaaggaattt
     1801 caaaatctac tatagaagaa atcttgaatg attttgattt ttcggaagtt gctcaacgtg
     1861 tagccaataa actattgaaa aaatatgagg gaaaacttcc agctcgtgcc ctgcaagata
     1921 agattatcca gaacttgact aacaagggct tctcttattt tgatgctaaa attgcctttg
     1981 acgaattgga tagtcaagtt gaccaagaaa cgactcagga actcatcttc aaggaacttg
     2041 ataagcaata tactaagtat gcccgaaagt atgaaggata cgaactgaag cagcgtttaa
     2101 ctcaagtttt agcacgaaag ggctacgatt tttcggatat agcaagcgct cttagagaat
     2161 atctttaata tttccaagtg aaattcacag attttaggta attttatggt acaatagtaa
     2221 atgataaact tataaattgt agaaagttgg ttagttatga agcttccaaa agaaggcgac
     2281 tttattacaa ttcaaagtta taagcatgat gggagtctcc accgaacttg gcgggacacc
     2341 atggtactaa aaacaacaga aaacgccatt attggtgtca acgatcatac acttgttacc
     2401 gaaagtgatg gtcgtcgttg ggtcactcga gaaccggcta ttgtttactt tcacaagaaa
     2461 tattggttta atatcattgc catgattcgt gataatggaa cttcttacta ttgcaatatg
     2521 gctagcccct actatctgga tgaagaagca ctgaagtata ttgattacga tttggatgtt
     2581 aaaattttta cagatgggga aaaacgtctc ttggacgttg aagaatacga gcgtcacaaa
     2641 cgcaaaatga attattctga tgacttggac tatattttaa aagaacatgt caaaattctt
     2701 gttgattgga ttaacaatgg acgtggtcct ttctcagaag cctatgtaaa catttggtac
     2761 aagcgctatg tagaactaaa gaatcggtaa agttgtcaaa ggtcaggaac aaaatcctga
     2821 ccttgttttt ttggtagtat aaaataaatt gtgtaaacac aaaaaggaat aaatccatta
     2881 tagcagagtt acaacacatt actagaaaga gatttatgca gaattcgtaa aatatataaa
     2941 acaaatagat atactattat tttttaatgt ctttattcct agtaagttta caacaaactt
     3001 atatcgttta atacaaaaaa tacgaaaatg attagtataa aaaatacagg tcaacttcgt
     3061 atcaaaaaca tttttttgta tttccacata gcatcaatca tttagtacaa tattttaaaa
     3121 acaatatctt aacagagaaa atgatattta atctatcagc tcatttaatc gtttttgaaa
     3181 atataaagca atacttttag attcaataaa ctcaaaatat tttatgacat tgtccatttg
     3241 tttaattcca gattctttag attctgtcag gtatatttta tatccttcta caaatttgaa
     3301 tgtagatttt tcaaaaactt ttgtgtcatc ttttaataat ttttgtaatt tcatttcaaa
     3361 gtagtctgca tatattagat gtgaattttc aaggcaacag aaccaaaaat ttaaacaagc
     3421 tgacacaact aaatgtctat tcttgccgat tttttcgtaa taatgtgtac gctctagtat
     3481 ttcttttccg accatgtaaa tataatctat ttcaaaaaga tgatataaat taccaatcag
     3541 cgttatctca taggacttcc atcgttcctt ctggaataaa tagtcatata ctaaatttag
     3601 atcatctcta ctaactacat gattacaatc tagctgattt cataatccct gaaccataat
     3661 tgtatttatt ttatgagttt ttcccactct tctcaaaaag tttttgttgc ttatttttta
     3721 ttacctccaa tcctttaata ttcaaactat aaaaatttgg agataaatta accaaaaaat
     3781 catcacgctc cgatctttta taatgttcta agtgattaca aaaattctct atcgaaacat
     3841 tgatatttga taataattca aaaaatgttg aaagagaaat ttcattttct cccctttcaa
     3901 atctagaaag ttgagatttt gatatagaat cagctgcagc atactctaaa gaatatccgt
     3961 ttaattttct aaaatatcga aaagcttctc cgtaattttt cacactttca ttcccttaac
     4021 tttcttttcg agcgataaac ataccatatt ctttaggaat gatcaacata ccattattaa
     4081 actcactttc caatctttta cgtattattt cctcttctag tgaacctatt tctgaaattc
     4141 ctttaaacga ttggatgtat ttaactaggt catctatact agttacctgt aactcatcat
     4201 catagagtaa tgtatcgaca gagttaaaat acctactcag gtacctttta ccattttgta
     4261 aagtaaacgt tctattttct aaatcttgat taacctcatc tttaaataaa tttgccaaat
     4321 aatttacaac tccattttca ccaaatgtag cacagtaaaa aattcctccg gtttttaaga
     4381 ccctattcac ctcagagaga gctttaggaa tatcattcac atgatgtaga agcatattag
     4441 caataacaat atcaaaagtt tcattctcaa aagaaatctt ttgaatatcc attatctcat
     4501 aattgacatt gtttctattt ccaatcactg acttcgttga ttttaccata tctttagaaa
     4561 aatctgtaac aatcaactgc ttcattttat ctatagaatc actattactt ttccacaatt
     4621 ctcctgtacc acatcccaat tctagaacct ttacttcatc agtgatttgg tagttagaaa
     4681 atatccaatt attaaatccc aatttatttt ttgaatactt cttatgcaat tctactcgaa
     4741 tatcaagatt atcatgactt ttatattgtt caattacttt atcaatcatt ttaaatgacc
     4801 tccactctat aatttggcat tatatcacaa gaataaagat agtgttaaat aagttgtata
     4861 aatgcaaaaa aggaatattc cgttatagca gagttgtaac acatttctat aaagaaattt
     4921 attcctacga ctcagtttgg catgcttaac ttcctaactc aaaaacaaag catcgattaa
     4981 tttatccgtt cttcttttga aacagatttg aactgataat tgctcgtttt aatttaagaa
     5041 gctcttttga gcaaaacttc atttttttaa gagtccaaca atttctgtct atcgcttttc
     5101 tactagcaaa aaaaactacc ttgaggcaag ttttcattta tatatctaat ttcgtaatag
     5161 tatagtaaaa tgaaataagg acagtcaaat cgatttctaa caatgtttta gaagtaaagg
     5221 tgtactattc tagtttcaat ctactataaa tttgatatga gaatagtctt tctcaacatc
     5281 cttacccaac aagaatgctg tagcgtcctt cttaacttga accaggtcaa tattctgggc
     5341 ttgggctgca tagacgcagc cacaataaca ttgacgatag atatcatact cctcacacat
     5401 ctctactgaa cgtttgtagc cttgattttt cttgaaatcg ttgggaagat agtgggtcgt
     5461 gtaaattttt tgcacatcga ttccgatgct gttgatggtt tgagaattct tatgaggact
     5521 gatggtcaag gctgaaccaa agtagtcaaa gcccaagtcc atagccactt gcgctgtttt
     5581 atccagtcgg tagtcaaaac aaaccttgca acggtcgcca ccttcgggct cctcctctag
     5641 tcccctaact agttttcggt attaattggg ttcgtaggga gcttctaggt actgaaccgt
     5701 atttcctgtc cgctcattaa aatcactaac aaatttcttg atgacataga cccgcttatg
     5761 gtattctacc ttgggatgga tattagaatt ggcaaaatag atggtcacat ctgcatactt
     5821 ggtcaaatat tctagtgtat aggtactaca aggggcacag caaacatgca cgagaatggt
     5881 tggccgctgc tcatttttct cccatgcttg taccattttc tgcatgacac ggtcataatt
     5941 aatcttctga ttggggggca tcttgcacag aatttcttct acatcgatca tgttcttctc
     6001 ctttttctag tcttatttta tcatataagt taggagagct caaatcaatt tagaagtgaa
     6061 tattataaaa agaagggtta gtcattccct ccttttgtgt tttttataag ttgttttcta
     6121 tagaaagctt acatcatccc gcccatcatg cttggatcca ttgctggagc tggggctact
     6181 ggttctggtt tattggctac gactgcttct gttgtcaaaa tcaagctggc tacagatgct
     6241 gcattttgta gggctgaacg actcacttta actggatcaa tgataccttg atcaatcatg
     6301 ttaacccact cgccagttgc tgcgttgaat cctataccaa gctcagcatt tttcaaacga
     6361 tcgataacga tagatccttc aaatcctgca ttgtgagcaa tttgacgaac aggttcttcc
     6421 aaagcacgga gaacaatatt acgtcctgtt gcttcatctc ctgtcaattc caaggtagca
     6481 acagctggaa tcacattggc aagagctgtt ccaccacctg caacaatacc ttcttcaaca
     6541 gctgcacgag tagcgttgag ggcatcttca atgcggagtt tcatttcttt caactcagtt
     6601 tcagttgcgg ctccgacctt aataaccgct acaccacctg acaatttggc caagcgttct
     6661 tgcaattttt cacggtcaaa ttcagaagtt gtagtttcga tttgagactt gataaccgca
     6721 acacggtgag aaatcgcttc aggatttcct gcaccttcta caataaccgt gctatctttg
     6781 tccacggtca ctctcgctgc ttgaccaaga gcttcaattg tcgcatcttt caactcaaga
     6841 ccaaggtctt ctgtgataac tgttccgcct gttaagatgg cgatatcttc aagcatagct
     6901 ttgcgacggt caccaaaacc aggtgccttg actgctacta cgttgaaggt tccacgaatc
     6961 ttgttcaaaa caagagttgg aagagcctcg ccatccacat catccgcaat aatcaagagt
     7021 ggacgattgc tttggagaat gctttccaaa agtggcaaga tttcttggat attggaaatt
     7081 ttcttgtctg taatcaaaat gtacggattt tcaaggtcag ccaccatttt ttcgctatct
     7141 gtcaccatgt actgtgaaag gtaaccacgg tcaaactgca ttccttctac gacttcaagc
     7201 tctgtttcca taccacgtga ctcttcgatg gtgatgacac cgtctttgcc aactttttcc
     7261 attgcttcag agatgtactc accaactttt tcagaacgag aagatacggc tgcaacttga
     7321 gcgatagctt ctttattggc aacagggatg gcgttgtttt tcaaagcttc aactgctgcg
     7381 gcaactgctg tttcaatccc acgacgaata ccgattggat ttgcacctgc tgtgacgttt
     7441 ttgattcctt cacggacgat agcttgggtc aagactgttg cagtcgtagt tccgtcacct
     7501 gcgatatcat tggttttaga agctacttct gatactaact tagcacccat attttcaaaa
     7561 tggtcttcca attcgatttc tttggcaatg gtcacaccgt cattggtaat caagggtgaa
     7621 ccgaatgact tttcaagaac gacattgcga ccttttggtc ccaaggttac tttaacagtg
     7681 tctgcaagga tatcgacacc acgaaccatg gctgaacggg catctgatga aaatttaatt
     7741 tcttttgaca tacttacttt ctccttctat tcctcaatga ttgccaagat gttagcttcg
     7801 cctacgatga tgtacttttc atcgccatct ttgacatcaa gacctgcgtg ggcttcaact
     7861 aagacacgat ctccagtttt aacacttgga gcaaccaagt caccgttcaa ggtacgaaca
     7921 ccttgtccag tagccacaac ttgagctgtt ttggtttttt cttgggctga gcctgcaagg
     7981 acaaagcccc caacggtttg ttctttttct tctattttta agaccacacg gtcccctaat
     8041 ggtttcaaca tctgatttcc tccataatga gatagatatt attagcactc tttgaacttg
     8101 agtgctaatt cataattcta ttgtatcact tggtcagaaa tagtcaagaa aaaagtctga
     8161 ctttctcaag ataaaaagcc tgagaccaac tcagactttt taatgtttat actcaatgaa
     8221 aatcaaagag caaactagga agctagccgc aggctgctca aagcattgct ttgatgttgt
     8281 ggataaagct aacgtggttt gaagagattt tcgaagagta ttaaaatggc aattcttcct
     8341 cttccaagac caaatctgcc aaatcttggc ctgcattatt ttcacgcatg gcacgttgag
     8401 cacgactttc taagagttgg aatcctgtca caaggacttc ggttacatag ttcatctgac
     8461 catttttctc aaagcgacgg gtacgcaatt ctccatcaac ggaaatgaga ctacctttgg
     8521 ttgcgtagct tgccaaagtt tctgctagcc tgccccatag gaccatattg acaaaatcag
     8581 cttcacgttc accgttttgg tctttgtaac gacggttgac agcgatagtt gctcgcgcta
     8641 ccgacttgtc attgttggtt ttgtgcaatt ctggtgtaga cgttaaacgc ccaat
//
LOCUS       DAVHLA010000068         8547 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVHLA010000068 DAVHLA010000000
VERSION     DAVHLA010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8547)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8547)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8547
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.068"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(115..390)
                     /locus_tag="VVO77_001992"
     CDS             complement(115..390)
                     /locus_tag="VVO77_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEU5693950.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(496..1335)
                     /locus_tag="VVO77_001993"
     CDS             complement(496..1335)
                     /locus_tag="VVO77_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU5693951.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRIGRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1477..2325
                     /locus_tag="VVO77_001994"
     CDS             1477..2325
                     /locus_tag="VVO77_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEU5693952.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSAWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFIFGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2418..3335)
                     /locus_tag="VVO77_001995"
     CDS             complement(2418..3335)
                     /locus_tag="VVO77_001995"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEU5693953.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            3770..3975
                     /locus_tag="VVO77_001996"
                     /pseudo
     CDS             3770..3975
                     /locus_tag="VVO77_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            4309..5615
                     /locus_tag="VVO77_001997"
                     /pseudo
     CDS             4309..5615
                     /locus_tag="VVO77_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(5755..6048)
                     /gene="rpmA"
                     /locus_tag="VVO77_001998"
     CDS             complement(5755..6048)
                     /gene="rpmA"
                     /locus_tag="VVO77_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEU5693954.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(6065..6409)
                     /locus_tag="VVO77_001999"
     CDS             complement(6065..6409)
                     /locus_tag="VVO77_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEU5693955.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENS
                     SEFVQTRVITEN"
     gene            complement(6425..6739)
                     /gene="rplU"
                     /locus_tag="VVO77_002000"
     CDS             complement(6425..6739)
                     /gene="rplU"
                     /locus_tag="VVO77_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEU5693956.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEADQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(6775..6862)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(6957..7556)
                     /locus_tag="VVO77_002001"
     CDS             complement(6957..7556)
                     /locus_tag="VVO77_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEU5693957.1"
                     /translation="MTFCAGYVDAYTFIVRGNTLVAGQAGNVVFLSVELIQNNVSDVR
                     DKLLTLITFIMGVFLLTIYKEKLRIVKKPILSLIPLAILSIIIGFVPQTVDNIYLVQP
                     LAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLAFGDYFRTKHTPFLREGFIFVSLL
                     SSFVLGDVFSAYLTIFYHEKTILGVPIMMSIFYLSMLFA"
     gene            8026..8325
                     /locus_tag="VVO77_002002"
     CDS             8026..8325
                     /locus_tag="VVO77_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEU5693958.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
BASE COUNT         2733 a         1728 c         1405 g         2681 t
ORIGIN      
        1 tacaatattt tcggaacatt caacttttta actctattta ttactagatt tcataattaa
       61 aaagcctact gaccaagcta gaaagcttga tacaataggc tttttaaaga ctgattattt
      121 aacagcgtct ttaagagctt taccagcttt gaatgctggt actttagaag ctgcaattgt
      181 catttcttta ccagtttgtg ggttgcgacc tttacgttct gcacgctcac gaacttcaaa
      241 gttaccaaaa ccgatcaatt gaactttttc accagctgca agatagtcag ctactgctgc
      301 aaatacagct tcaactgctg ctgctgagtc tttcttagtc aattctgtag cttctgctac
      361 tttagcgatc aaatcttgtt tgtttgccat gttaatgatt cctccagata atttctaatt
      421 aacaaatata atcatatcct aaaatccctt ttaggtcaag ttaaaaacgc tatttcttcc
      481 aattttattt attttttagg agtggtaacg tatcaaaata gcccaagcgt tctcacccgt
      541 gtgagtttga ataatggaac ccgtttccaa aacagaaatt ggcttttcaa cataagcttg
      601 taagctttct ttcatctctt ttgcccaatc atcactacca gaatatgaaa ttccaatctc
      661 tgctacagca cgttcagaaa gcgatgttat caactcatct aaccattttt taaatgtttt
      721 agttccacga cctttaacca ttggctgcaa ttcatggtct ttcatttgca tgacaacacg
      781 gatattgaga agggagctca acaagccagt tacacggcca attcgtccac ctttgacaag
      841 attttccaaa gttgaaacac caatataaag ctctgtatgg tttttaacct cttctacatg
      901 agataaaatt gcctccatat ctttaccttc ttgagctaac ttcgcagcct caacaacttg
      961 gaatttcagg gcttggtcag tgaaggaact atcaacaaca gtcacatctg cagtagatag
     1021 gctagcacct tggcgtgctg cttctaccgt acccgaaaga gcatgggaca tatgaatagc
     1081 aagaatctgg ccaccatctt tgcataggtc ttcaaaaatc tcagcaaaga cacctacagg
     1141 tggctgactt gttttcggaa gattcttact ttcttgcatc aactgaagaa atttaccttc
     1201 ttctttcaaa tccgcatcag aataaacaac attatcaatc attacagata atggaacaat
     1261 tgtaatatct aattgcttta ctagttcagg ttcaatagta acagatgaat cggttacaat
     1321 cttaattttt gtcatagtat caatctttct attttaggat tcagattggt ttccttactt
     1381 ctaattatat caaaaaaaag attaaaaatc ctaatggagt caatcaaatt ttccgtaaaa
     1441 tttgatataa tcaacttata agaaaagagg tgtcctatga ttaaaaaaat ttaccccatt
     1501 tttaccattt tactaggtgc tgctatttat gcttttggac tgacttattt tgtagttccc
     1561 catcatctct ttgaaggagg ggcgacaggc attaccctca tcacctttta tctttttaaa
     1621 atccctgttt ccctcatgaa cctgctgatt aatattcccc ttttcatcct agcttggaag
     1681 atctttggag ccaaatccct ctattctagt ttactaggaa ccttagcttt gtccgcctgg
     1741 ttagcttttt ttgagcatat tccccttcat attgatcttc aaggtgattt actaatcaca
     1801 gcccttatag cgggaatcct attgggaatt ggccttggaa ttatttttaa tgctggaggt
     1861 acaactggcg gaactgatat tctagctcgt attctcaaca aatacactca tatatccata
     1921 ggaaaactgc tctttatctt agatttttgt attctcatgt tgattctcct aatcttcaag
     1981 gatttgagat tggtttccta cacgcttttg tttgatttta ttgtttctcg tgttattgat
     2041 ttgattggtg aaggaggata tgccggcaaa ggctttatga ttatcacaaa acgtcctgac
     2101 caacttgcta aggcgattaa tgatgacctc ggaagaggtg ttacttttat ttttggtcaa
     2161 ggctactata gtaaagaaaa tttgaaaatc atctactgta ttgtcggaag aaatgaaatt
     2221 gtgaaaacga aggaaatgat tcatcgaatc gatcctcaag cctttataac tattacagaa
     2281 gcccatgaaa tcctaggaga aggcttcacc tttgaaaaag aataaaaaga ggtaatgtcg
     2341 tgacctcaaa agttagacta aatcatctat cttttgggtt acagacaacc tcttttttgt
     2401 tttatttact caagctctta agaccaattc cgagttactt cttcatcagc ctttaactga
     2461 tccactaatt ggtcaactga gtcaaatttg gtcatatcac gaatgcgatc aagccaataa
     2521 accatgacgg tttccccata aatatcttga ttaaaatcaa aaatattgac ttcaaaacgt
     2581 gcttcttctc catcaaaggt cacatttttc ccgacactag ccatagcacg atacttctgt
     2641 ctttgaatct caacatcaac gacataaacg ccatctgctg gcatataagt acggtctaaa
     2701 agcactaaat tcgctgtcgg ataaccaatt gtacgaccac gagcattacc atgaactacc
     2761 atacctcttg atggaagcgg tgcccccaaa agttttcctg cttctttcac atttccatct
     2821 aaaatagctt gacggatacg agttgaacta atctttcctt tctcatcttc tacaggtgga
     2881 acaatgataa cttctccatc aaagtaatcc tttaaatctt ctgctgtttt tttgtcagaa
     2941 ccaaatgtat aatcaaaacc tgcaacaata attttggcat tcatagcctt gatataagtt
     3001 gcaaagaatt cttgtgcagt gagactagcg aattgactac taaaatcaag gagatataat
     3061 tcttctacac cttcgcgctt tagttttctt tcacgttcag cagggttcaa aatatgcaaa
     3121 aacaaatctg gatgataagg ctctaaagcg atctttggag attcattaaa ggtcataacg
     3181 acgataggta ataaatcctt tctcgcagcc ttgttggcaa cacgaaataa ttcttgatgc
     3241 cccttatgta tgccatcaaa atagccgaga acaacgactg aatcagatgg tgtgccaata
     3301 tctttttggt tttttatagg aatagtaata atcataaaat aattatatca tagcgatagc
     3361 tatttctgga acagaaaatc tgaaatgttg tttttttcac atgaagtgta cctgttttca
     3421 aaaagcactt tattctatcg ttgcttaact atgaactttg caatattctt ctcaaaaact
     3481 tgtaggacat cttcaaaatt ttgcaaggag tgattagact tgttcggtaa ccataaagtg
     3541 tcatactatg cttatgtatg aaaaagcaat gcaactaact cctgagaact ttaaattact
     3601 aattggtgcc gaaaaggtag aatttagaat cgaggtacac ctatggctgt aaaatttaca
     3661 aaatgagaca acttgggcaa gatgtttgaa gaatttccta aactccctga tttgaagcaa
     3721 gtcactttcc ctgatgacaa aaaaagccaa agcagtaaag aaaaactaga tgactgcttt
     3781 ccaacaactt ccatctagtg tgcttcagac tgggctattt ttctctccat ctgttagctt
     3841 ggattctcag accgtttcag ctaaagaata tcttttccct tatcagaagg aacggctcaa
     3901 gccattcaga caagtgaagg gacgacaagc caatatttga aaccagatag cagttcttat
     3961 agtcaattga aataaaatct gaagaaatcg agtaggaaac tcaaatcaat ttttaacagt
     4021 gttctattcc agattcatac tcaatgaaaa ttaaagtgca aactaggaag ttagccgcag
     4081 gctgtacttg agtacggcaa ggtgaaactg acgtggtttg aatttgattt tcgaagagta
     4141 tcaatccact atacatatta aaaagtatgg gtatcaaaat aaaaaggctc tataatattt
     4201 gtagtgggta aatccactat agatattatg gagcctattt tgtgtagaaa aaaagtccca
     4261 tatgacctat aatgaaaagc gatcaaacaa ctcattagaa agattcatat ggaacaatta
     4321 cattttatca caaaattact agacattaaa gaccctaata tccagatttt agacatcatc
     4381 aataaggata cacacaagga aatcatcgcc aaactggact acgacgcccc atcttgccct
     4441 gagtgcggaa atcaattgaa gaaatatgac tttcaaaaac cttctaaaat tccttatctt
     4501 gaaacgactg gtatgcctac tagaattctc cttagaaagc gtcgtttcaa gtgctatcac
     4561 tgttcaagaa tgatggtcgc tgaaacttct atcgtcaaga agaatcacca aattcctcgt
     4621 attatcaacc aaaaaattgc gcaaaagttg attgagaaga tttctatgac cgacattgat
     4681 catcagttgt ctatttcaac ttcaactgtc attcgcaaga tcaatgattt tcactttaaa
     4741 catgattttt cttgtcttcc tgagattatg tcttgggatg agtatgcctt cactaaggga
     4801 aagatgagtt tcattgcgca agattttgat aatcttaata ttatcactgt tcttgaaggc
     4861 agaacacaag ctgtcatccg aaatcacttt cttcgctacg atagagccgt tcgttgtcaa
     4921 gtgaaaatca ttacgatgga tatgtttagt ccttactatg acttggctaa acagcttcgc
     4981 tttcaaattt ctaggctcag gctgaaacag tctcccagac tgtttcactc ccgaatgcta
     5041 aaatcgttct tgatcgcttt cacattgtgc aacatcttag ccgtgctatg agtcgtgtgc
     5101 gtgttcaaat catgaatcag tttcatcgaa aatcccatga atacaaggct atcaagcgct
     5161 actggaaact cattcaacag gatagccgta aactgagtga taaacgtttt tatcgtccta
     5221 cttttcgcat acacttaaca aataaagaaa ttcttgacaa gattttaagc tattcagaag
     5281 acttgaaaca ccactatcag atctatcaac tcttactttt tcactttcag aacaaagacc
     5341 ctgagaaatt tttcggactc attgaggaca atctgaagca ggttcatcct atttttcaga
     5401 ctgtctttaa aacctttcta aagaacaaag aaaaaatcgt caacgctctt caattacctt
     5461 attccaacgc aaaattggaa gcgaccaata atctcatcaa acttatcaaa cgaaacgcct
     5521 ttggatttcg gaactttgaa aacttcaaaa aaaggatttt tatcgctctg aacatcaaaa
     5581 aagaaaggac gaattttgtc ctttctcgag cttagctgac ttcaacccac tacagttgac
     5641 aaagagccta aaaaaacagg ctctccgaaa actcggaaag ccttatttta agctgtttct
     5701 agcttcctca cctttatatt tcaaggttcg ggataaaagg ttcaatggac ctttttattt
     5761 agcgattggg taaacagaaa cttgtttttt atcgcgtcct ttacgttcaa agcgtactac
     5821 gccttcaact ttagcgaaca aagtatcgtc tccaccacga ccaacgttta cacctggata
     5881 gatgtgtgta ccacgttgac ggtaaaggat tgatccacct gttacagttt gtccgtcagc
     5941 tgctttagct ccaagacgtt tcgcttgtga atcacgtccg tttgatgtag aacctccacc
     6001 ttttttgtgg gcgaaaagtt gcaagttgtt aagagtcatt tttaacataa tgttttcctc
     6061 cgtgttagtt ttctgtgata actctggttt ggacgaactc agaagagttc tccgataagt
     6121 ttgccatacc taagaaaaat gattcaaaga ataactgggt catttctctc tggtgtgaag
     6181 gaagatcttt tggtatttca accatcagat agccaccttc atcttcgttt aattctagga
     6241 ttggttcata gcctgcaaat ttctcaatag aattgataaa gttaatggca agcgtagaaa
     6301 ccgatgcaca cacgacatct aagccgtatt cgccactctc ggcgtgtcca gtaatttccg
     6361 cactcctcag ctcgccatct tcggctctct caaagactgc ctgtatcatg tgttctcctt
     6421 aaaattaagc gttgattgcg ttgatgacaa cttttgtata tggttgacgg tgaccttgtt
     6481 tacggtggct acctttttta ggtttgtact tgtaagtaac cactttcttt tgttttcctt
     6541 gtttttcaac agttccaact acagtagctc cagcaacaag tggagttccg acaacagtgt
     6601 tttcaccacc aacaagaaca acttcgttaa aagtaacttc ttgatcagct tcaacgttca
     6661 atttttcaac gtaaactgct tgaccaactt caactttaac ttgttttccg ccagttttga
     6721 taattgcgta tgtgctcatt atgcacctcc tatgattttt atgggtttcc ccgatttttt
     6781 gtgaagactc gcctagcatc gtgggacgaa ccacttaaac ttgaataatc aagcaacgat
     6841 gttcgtgcgg ttgcacagga tcgtgcatag tcaactcttc aagtatagca tatctcctat
     6901 tttcttacaa gtaataacac ctaaaatgaa gctttttctt ttactttttt ctgccactag
     6961 gcaaaaagca tactgagata aaaaatgctc atcataatag gaacaccaag aatggtcttt
     7021 tcatgataga aaatcgtcaa ataggctgaa aagacatcgc caaggacaaa actactaagc
     7081 aggctaacaa atatgaaccc ttcacgcaaa aaaggagtgt gcttagttcg gaaataatct
     7141 ccaaaagcta gcattgttcg tttgatattc cctgtcataa aggcattatt gtaggcaata
     7201 cccgaaacct caccaaaagc agttgtcacc agtcccatac agaaggccaa gggctgcact
     7261 agatagatat tatctacagt ttgtggcaca aaaccaataa ttattgatag gattgctaaa
     7321 ggaatcaagg acagaatagg ttttttcaca attctcaatt tttccttata aatcgttaat
     7381 aaaaagactc ccattataaa cgttattaag gttaaaagct tatccctaac atccgaaaca
     7441 ttattttgta ttagctctac cgaaagaaag acaacatttc cagcttgtcc agctacaagg
     7501 gtattccctc gaacaataaa agtgtaagca tccacatatc cagcacaaaa tgtcaaaaaa
     7561 gtgctaacct tttagactga cgtgatattt ttcttatagg taataacctc attttccctc
     7621 ccattgtatt ttctcttaga aatattgtac catttctttc taaaaaatcg tagactacca
     7681 tttagatttt actattagca taaaaataat aatagacaac tatttatcca aaaatagata
     7741 gaggtaacat gtttgcaaac aaagcatacg aacctttagt aaaatcattt ccatgaaact
     7801 agaatagagc ccctcttagc aaaaatcatt attttaattt atttctaatc actccttgac
     7861 ataaataact ctcaccaata aaagactatg tcttaaaaaa atggtataat aaaatcaata
     7921 cctgggcttg atggctatgc tactaataac aattaggaga gaaaatcagg cacttgttaa
     7981 caacaaggat tatccccttg agatgaaagg aactttagaa atcttatgat gaacatgcaa
     8041 aacatgatgc gtcaagcaca aaaacttcaa aaacaaatgg aacaaagcca agctgaactt
     8101 gctgctatgc aatttgttgg caaatctgct caagatcttg tccaagcgac cttaactggc
     8161 gataagaaag ttgtcagcat tgatttcaat ccagctgtcg ttgacccaga ggaccttgag
     8221 actctttctg atatgaccgt tcaagccatc aactctgctc ttgaacaaat cgatgaaact
     8281 actaagaaaa aactgggtgc tttcgctggg aaattgccat tctaaaaaca aggagctaga
     8341 acaatacttg tcgataacaa aggctaagaa aggtgcaaaa attataaaaa acgcatagta
     8401 tcaagcaacc taaaactttg ggctctataa tatttgtagt gggtaaatcc actatagata
     8461 ttatggagcc tattttattg tagaaaaaaa tcccataaga tctataatga aaagcgacca
     8521 aacaactcat tagaaagatt catatgg
//
LOCUS       DAVHLA010000069         8329 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVHLA010000069 DAVHLA010000000
VERSION     DAVHLA010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8329
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.069"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(16..174)
                     /locus_tag="VVO77_002003"
     CDS             complement(16..174)
                     /locus_tag="VVO77_002003"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693959.1"
                     /translation="MQLGDFAKAGVGGAAARGLQLGIKTGTWQGAATGAAGGAILGGV
                     AYAATCWW"
     gene            complement(111..245)
                     /locus_tag="VVO77_002004"
     CDS             complement(111..245)
                     /locus_tag="VVO77_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin class II family protein"
                     /protein_id="HEU5693960.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWEILPKQVLEEQQQEVFN
                     "
     gene            complement(314..583)
                     /gene="blpJ"
                     /locus_tag="VVO77_002005"
     CDS             complement(314..583)
                     /gene="blpJ"
                     /locus_tag="VVO77_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HEU5693961.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGSGLTCLGGMVGDKLGLSW"
     gene            complement(1049..1246)
                     /gene="blpI"
                     /locus_tag="VVO77_002006"
     CDS             complement(1049..1246)
                     /gene="blpI"
                     /locus_tag="VVO77_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HEU5693962.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSSL"
     gene            1527..3680
                     /gene="blpA"
                     /locus_tag="VVO77_002007"
     CDS             1527..3680
                     /gene="blpA"
                     /locus_tag="VVO77_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter BlpA"
                     /protein_id="HEU5693963.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLVIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNGLLSFLPL
                     IFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYIL
                     QQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDANSII
                     DALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMFIIFSFMKPFEKMNH
                     DVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQT
                     SLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQS
                     AKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDINLTIK
                     QGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINYLPQQ
                     AYIFNGSILENLTLGGNHMISQEDILKACEVAEIRQDIERMPMGYQTQLSDGAGLSGG
                     QKQRIALARALLTKSPVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAE
                     RTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            3691..5052
                     /locus_tag="VVO77_002008"
     CDS             3691..5052
                     /locus_tag="VVO77_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEU5693964.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSIISSIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLANSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTSNPHQSILNRY
                     LVASQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPIITDTREVLITYYVASDYLPLLDKGQTVRLKLEKIGNHGITIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTAKKTYFDYFKDKILT
                     HSD"
     gene            5109..5264
                     /gene="blpC"
                     /locus_tag="VVO77_002009"
     CDS             5109..5264
                     /gene="blpC"
                     /locus_tag="VVO77_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEU5693965.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGLWEDILYSLNIIKHNNTKG
                     LHHPIQL"
     gene            complement(5309..6649)
                     /locus_tag="VVO77_002010"
     CDS             complement(5309..6649)
                     /locus_tag="VVO77_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU5693966.1"
                     /translation="MNVAWILLYTLVTHGLKIVIFFKVDGIGLTFERIFKAFLLKILL
                     AFVFVMIGYMVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQEQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRREILDTGFQK
                     SLTKINWIMGAYYLVIQSLSYFEYEQGIQSTTVRHLILVFYLLFFMGVIKKLDTYLKD
                     KLHDRLDQEQVLRYRDIERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYDLVLRDSSQKLQDNKYDLGRLVNVRDRALKSLLAGKFIKAREKDIVFNVEVPEEI
                     QVEGMRLLDFLTIVSILCDNAIEASAEAGQPHVSIAFLKSGAQETFIIENSIKEEGID
                     ISEIFSFGVSSKGEERGVGLYTVMKIVESYPNASLNTTCQDQVFRQVLTMIPTE"
     gene            complement(6663..7400)
                     /locus_tag="VVO77_002011"
     CDS             complement(6663..7400)
                     /locus_tag="VVO77_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU5693967.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIREQDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRPHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            complement(7405..7743)
                     /locus_tag="VVO77_002012"
     CDS             complement(7405..7743)
                     /locus_tag="VVO77_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU5693968.1"
                     /translation="MKHMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEKASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            8019..>8329
                     /locus_tag="VVO77_002013"
     CDS             8019..>8329
                     /locus_tag="VVO77_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEU5693969.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     N"
BASE COUNT         2749 a         1757 c         1295 g         2528 t
ORIGIN      
        1 ttttaaaatc cataattacc accaacatgt tgctgcatag gctacacctc caagtatagc
       61 tccacccgca gcaccagttg ctgcaccttg ccatgttcct gttttaatgc ctagttgaag
      121 acctcttgct gctgctcctc caacacctgc tttggcaaaa tctcccaatt gcatccgcca
      181 ccttcaacgc aagcaagcat ttcagtatcc ataacagaaa attgtgacat catttttgta
      241 tccatgacaa atactccttt tttaaaaaac taaaataaat cagaatagaa tcctcataat
      301 tttactataa gtcttaccaa cttagtccca atttatcacc aaccatacct cctaagcatg
      361 ttaatccact cccaattgca ccaatgtgtg ctccaacaaa tgcaccagca agtccagcta
      421 ctcctaaagt ggccaaacct gctccagttc caccagttat aattcccgta gtgactcctg
      481 taatcagtgc attttgacaa tcagtggagc tatacccccc ttcaactttc gcaagcattt
      541 cagtatccat aacctctaac tgtgacaaca tttttgtatt catgatgaat acctcctttt
      601 tattttcaat ttgttaccaa agtcttaaat tcaataaaca aatagatttt ttatagtatc
      661 tttttgattt tcttaaaaaa gtatatacgt ctactatctt cttaaaggta gcagtaccta
      721 tttttagtct aagatttcaa taatcttgag tatctaaaat atcttaattt cgttattctc
      781 cttgcaataa aaagttttac tatactattt attaacttgc agaaagcaaa aaatattagt
      841 aaataatagt ttatagttaa gttttttatt cctaccaatc catcaactaa gtaaagcatc
      901 aacgattaca taaacgattg ataatataat taaaattttg ctaactatct tattctcatc
      961 attcttagat aactttgata ttttgtaagt aagtaaataa gacagtaaat taatagcgat
     1021 aataatacta tatttaagaa tcataatctt acaaagagga cataattcct gaacctacac
     1081 aaataagtgt tgctgctccc ccagttatcg gaccagtcgc agcagctaat agtactgctc
     1141 caatacaacc accgattgca gatcctaaat tgcctcttcc tccactaact atttcgagtt
     1201 cttcattatc cataacagaa aattgttcca tcatttttgt attcatgaca aatactcctt
     1261 ttttattttt aatttttgtc ttgttgcaac tttgacaagt ttagtatatc attatttttt
     1321 aatttttttc atccaaatct tgaattgcca tcgaaacgtc ttgaattagc ttttttattt
     1381 caagccacct ctaaatgttt aaaaaaaata atttctaatc acttttttac cattcaggaa
     1441 gttttaatga ctattcaaca tttcataaaa tatgaactta gttttatggc ataatatacc
     1501 tatccactat atgaaaggaa ttgccaatga cttcttataa acgtacattt gttcctcaaa
     1561 tagatgcgag agactgtggt gtcgctgcct tagcctcgat tgctaaattc tatggttcag
     1621 atttttctct agctcacttg agagaacttg caaagaccaa taaagaaggg acgactgctc
     1681 ttggcattgt aaaagccgct gatgaaatgg gctttgaaac aaggcctgtt caagcagata
     1741 aaactctctt tgacatgagt gatgtcccct atccatttat cgttcacgtt aacaaagaag
     1801 gaaaactcca acattactat gttgtctatc aaacaaagaa agactatctg gttattggtg
     1861 atcctgaccc ttctgtaaaa atcactaaaa tgtcaaaaga acgctttttc tctgaatgga
     1921 ctggagtagc tatttttcta gctcccaaac ccagctatca accccataaa gataaaaaga
     1981 atggtctact aagcttcctt cctctgattt tcaaacaaaa atctctcatt gcttacattg
     2041 ttctctcaag cttattggtc actattatca atataggtgg ttcttattat ctccaaggaa
     2101 tcttagatga atacatccca aatcagatga aatcaacttt aggaatcatc tcagttggtc
     2161 tggttatcac ctatatcctc caacaagtca tgagcttctc cagagattat ctcctaaccg
     2221 ttctgagcca gagattaagc attgatgtga ttttatccta tattcgccat atttttgaac
     2281 ttcccatgtc tttctttgcg acacgtcgta caggagaaat catttcacgg ttcacagatg
     2341 ctaactctat tatagatgcc ttggcttcta ccattctttc tcttttcctg gatgtttcta
     2401 ttctgattct tgtagggggc gtcttactgg cacaaaaccc taatctcttc cttctttctc
     2461 ttatttctat tcctatatac atgttcatca tcttttcttt tatgaagcct ttcgaaaaaa
     2521 tgaaccatga tgtcatgcaa agtaattcta tggttagctc tgccattatc gaagatatca
     2581 acgggattga aactataaag tcgctcacga gtgaagaaaa tcgctatcaa aatatagaca
     2641 gcgaatttgt agattatttg gaaaaatcct ttaagctcag taaatattct attttacaaa
     2701 caagtttaaa gcagggaaca aaattagttc tgaatatcct tatcctatgg tttggcgctc
     2761 aattagtcat gtcgagtaaa atttctatcg gtcagctgat tacctttaac acactttttt
     2821 cttactttac aactcctatg gaaaatatta tcaacctcca aaccaaactc caatctgcga
     2881 aggtcgctaa taaccgtttg aacgaagtct atctagtcga atctgaattt caagttcaag
     2941 aaaaccctgt tcattcacat tttttgatgg gcgatattga atttgatgac ctttcttata
     3001 agtatggttt tggacgagat accttaacag atattaatct cacgattaaa caaggagata
     3061 aggttagcct agttggagtt agtggttctg gtaaaacaac tttagccaaa atgattgtca
     3121 atttctttga accctacaaa gggcatattt ccatcaatca tcaggatatt aaaaacattg
     3181 ataaaaaagt cttgcgccgt catattaatt acctacccca acaagcctat atctttaatg
     3241 gctctatttt ggaaaactta accttgggcg gtaatcatat gattagtcaa gaagatattc
     3301 taaaagcttg tgaagtagct gaaatccgtc aagacattga aagaatgcct atgggctatc
     3361 aaactcagct ctctgatgga gctggtctat caggaggaca gaagcaacga atcgctctcg
     3421 ctcgtgctct tttaactaaa tctcctgttt taatactaga tgaagctact agcggtcttg
     3481 atgtcttgac tgagaaaaaa gttatagata atcttatgtc cctaactgat aaaaccattc
     3541 tctttgtagc ccatcgtctc agtatagccg aacgaaccaa ccgtgtcatt gttcttgacc
     3601 aggggaaaat cattgaagtt ggtagccacc aagagttaat gcaggcgcaa ggtttctacc
     3661 atcatctatt caataaataa ggagaatgtc atgaatccta atctttttag aagcgtcgag
     3721 ttttatcaga gacgttacca taactatgcg acagtgttaa ttatacctct ttcattacta
     3781 tttactttca tcttgatttt ctcccttgtt gccacaaaag aaattactgt cacttcccaa
     3841 ggagaaatcg cccctacaag tatcatttca tctattcagt caaccagtga taatcctatc
     3901 cttgctaatc atttagtggc aaatcaagta gttgaaaaag gggacttact catcaaatac
     3961 tctgaaacaa tggaagaaag tcagaaaact gccttagcaa ctcaattaca aagacttgag
     4021 aagcaaaaag aaggacttgg aattttgaaa caaagcttag aaaaagcgac tgatcttttt
     4081 tctggcgagg atgaatttgg ctaccataat acctttatga attttactaa acaatcccat
     4141 gatattgaac tgggtatcac aaagactaac actgaggttt caaatcaagc taatcttgcc
     4201 aatagcagtt catcagctat tgaacaagaa attacaaaag ttcaacaaca aattggagaa
     4261 tatcaagagc tgagagatgc tatcataaat aacagagcac gcttaccaac tagcaatcca
     4321 caccagtcaa ttttgaatcg ttatcttgta gcctcacaag gacaaacaca aggaacggca
     4381 gaggagccat ttttatctca aattaatcaa agtattgcag gtcttgaatc atctatcgca
     4441 agcctcaaaa ttcagcaagc tggtatcgga agtgtagcaa cttatgataa tagtttagca
     4501 accaaaattg aagtactccg cactcaattt ttacaaacag cttctcagca acaactaacc
     4561 gtggagaacc aattaacaga attaaaagta caactagatc aagcgacaca gcgcttagaa
     4621 aacaatacct taaccgctcc aagtaaaggt atcgttcatc tgaacagcga atttgaaggt
     4681 aaaaatagaa ttccaactgg tacagaaatt gctcaaatat tccctatcat cacagataca
     4741 agagaagtac taatcactta ctacgtagct tctgactatc tacctctact agataaagga
     4801 caaactgtaa gattaaaact ggagaagatt ggaaatcacg gcattaccat catcggccaa
     4861 cttcagacaa ttgatcaaac tcctaccaga acagagcaag gcaatctctt taaattaacc
     4921 gctcttgcaa aactatctaa tgaggatagt aaactcatcc aatatggctt acaaggtcgc
     4981 gtcactagtg taactgcaaa gaaaacatat tttgattatt tcaaagataa aattttaacc
     5041 cattctgatt aattttcaga taacactcta taactattta ttatcttatc aaaaaggaga
     5101 atcataacat ggataagaaa caaaacttaa cttcatttca agaactaaca actaccgaac
     5161 tcaaccaaat tacaggtgga ggactgtggg aagatatctt atacagcctt aatataatta
     5221 agcataacaa tacgaaagga cttcatcatc caatacaact ataaaaaata agaccgagta
     5281 acaagaactc tcggtcttat ttttttcatc attctgtagg tatcatagta agcacctgac
     5341 gaaagacttg atcttgacag gtagtattta aactggcatt gggataactt tccacaatct
     5401 tcataacggt atagagaccg acacctctct cctccccttt agaactaact ccaaaggaga
     5461 agatttcaga aatatcgatg ccctcttctt tgatggagtt ttcaatgata aaagtctcct
     5521 gtgctccact ttttaaaaag gcaattgaaa catgaggttg accggcctct gcactcgctt
     5581 caatagcatt atcacaaagg atagacacaa tggttagaaa atcaagcagt ctcatcccct
     5641 caacctgaat ctcttcagga acttcgacat taaagacaat gtccttttct ctagctttta
     5701 taaattttcc agctaggaga cttttgaggg cacgatcccg aacattcacc aatctgccca
     5761 ggtcatattt attgtcctgc aatttctgac tggaatccct taagaccaag tcatagacct
     5821 cttttatctg ctccatatcc tcctcttcaa tacccagacg taaacttgtc aagaggttgg
     5881 tgtagtcatg gcgaaaactc cttacttcct tgtaaagttc ctctatatgc cgactatagc
     5941 gttctatatc tctatagcgc aagacctgct cttggtccag tctatcatgg agtttgtcct
     6001 tcaaataggt atccaatttc ttgataaccc ccataaaaaa taggaggtaa aacactagaa
     6061 tgagatggcg aacagtcgtt gattgaatac cttgctcata ttcaaagtaa gacagacttt
     6121 gtatcaccaa atagtaagcc cccattatcc agttaatctt agtcagggac ttttgaaaac
     6181 ctgtatctag aatctccctt ctcaaactag taaaatcata gtccaaccat ttcaaaaagg
     6241 ctagagaaat gaagaaattg aaaattatta tacataaccc agtaaatgag tagccatcat
     6301 atacttgctc ttgtcccaaa aatggaagca caaaatagga gactcctcta taaaagagat
     6361 tcaccaatat cattggaaag agaccataaa agaaaaggag ttttttagga agccctctta
     6421 acaataagaa agacaagcct atgccgtaca agggttccat aaaataagat aggtaaacat
     6481 ttcctaccat atagccaatc attacaaaaa caaaggccaa cagtatcttc aaaagaaagg
     6541 ccttaaaaat cctctcaaaa gtgagaccaa ttccatctac cttaaagaaa atgacaattt
     6601 ttaatccgtg agtaacaagt gtatacaaca atatccaagc aacattcata aactctccta
     6661 gctcagtgta agttattaat agcctcagac acttccctga ccttataacg cgcgatcaga
     6721 cagcttccac cattgggaaa gaaaaggagt ttttctttct tatccaaatg caccacattt
     6781 gcaggattga tgagaaaaga gcgatggcac tgcaagagac ggggttcctg cttaaaaacc
     6841 tcctctaaac tcgccgtaaa ttctagcctg tccgtcttgg tatagagaat aacacgatgg
     6901 ggtcttgggg atgtttcgag atagtaaacc tctttgaaag gatattggaa ttgggcaaat
     6961 tttgatttaa agtaaaagca atcttccgcc agacttttac tatcttgact attggcatag
     7021 aggagggctg tctcgatacg agattcaaac tcctctgccg aaagggcctt atcaatgtag
     7081 tccaaagctg acacttggta gcgaaaggac agaggcataa actccgagtg agtcgtcaca
     7141 aagacgatta gggcataagg gtcttgttcc cgaatctttc tagctacttc cagtcccttc
     7201 atctcttcat ttcgaatctc aatatccaaa aagaatagct gatgggcccc cttctcatgc
     7261 acctctgcca gcagttggtc cggcttgcca aatacctcaa aagagctagg aatgatatga
     7321 tgtgctttca aaagtttctc aatcgtcgtt tcaattctag tctgttggga aaaatcatct
     7381 tctaaaacaa atattctcat cttcttactc tccctctttc aaccattttt gacgtatttc
     7441 tctatagcga cgtctggcat acttgacagc atattgacct tcttctccga gaaaaaggat
     7501 tctttcttga aaatcaatcg attttaattt atcaagatta accaaacaat ttcgatgaca
     7561 tctcatcaaa gtttccccac attggttctc aagattactt aaattttgaa gcatattaaa
     7621 actagctttt tctgtaacaa tctgtacggt atgggcttta gttggatgtg tttggatata
     7681 gtagatatcg tcgatgttta ctttatagac tgttttctgt gtctgaataa tcatatgttt
     7741 cattggattc tcctcctaag aaaagaataa cagaaaaggt ctagcccaag cacacccaat
     7801 cctaaacagt ctttgaaaac tcctaaaagg attattttct acaacatcat gatgagctta
     7861 caactatttt atcataaaat tcactcagcg caattcaaga catttcaatg acaattaaag
     7921 atttgaataa aaaaaaagaa ttaaaagtga taaactaaca gtatcaaaac acagttgcca
     7981 gaagtaagac tggcacccag attaaaggag gcattcccat gacagataca gaccccatca
     8041 aaagagctca tactttgatt actgacttaa acaaagccta ccaagcatgc aaacaggcaa
     8101 gcgctgacga cgtccgcttt caggagcaat taaactctat tcttggtttt ctagccaagg
     8161 ctgaaacagt ggataatcga ttcttgattg aactagaaaa attttaccag acttccagtc
     8221 ttctcatggg actcagcgct cttgatccag atgctccaac tcgcgccgct tggcgggcct
     8281 atgaccgctt ccactttgac caagtcaaga ccaagttaat actcaatga
//
LOCUS       DAVHLA010000070         7122 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVHLA010000070 DAVHLA010000000
VERSION     DAVHLA010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7122)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7122)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7122
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.070"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(61..558)
                     /locus_tag="VVO77_002014"
     CDS             complement(61..558)
                     /locus_tag="VVO77_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEU5693970.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(631..1992)
                     /gene="radA"
                     /locus_tag="VVO77_002015"
     CDS             complement(631..1992)
                     /gene="radA"
                     /locus_tag="VVO77_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEU5693971.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(2006..2521)
                     /locus_tag="VVO77_002016"
     CDS             complement(2006..2521)
                     /locus_tag="VVO77_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU5693972.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(2523..2966)
                     /locus_tag="VVO77_002017"
     CDS             complement(2523..2966)
                     /locus_tag="VVO77_002017"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEU5693973.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            complement(3023..3120)
                     /gene="ffs"
                     /locus_tag="VVO77_002018"
     ncRNA           complement(3023..3120)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VVO77_002018"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(3153..3620)
                     /locus_tag="VVO77_002019"
     CDS             complement(3153..3620)
                     /locus_tag="VVO77_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEU5693974.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYNILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(3821..5107)
                     /locus_tag="VVO77_002020"
     CDS             complement(3821..5107)
                     /locus_tag="VVO77_002020"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEU5693975.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(5338..5574)
                     /locus_tag="VVO77_002021"
     CDS             complement(5338..5574)
                     /locus_tag="VVO77_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HEU5693976.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRKDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            5839..6636
                     /locus_tag="VVO77_002022"
                     /pseudo
     CDS             5839..6636
                     /locus_tag="VVO77_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(6671..6880)
                     /locus_tag="VVO77_002023"
                     /pseudo
     CDS             complement(6671..6880)
                     /locus_tag="VVO77_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7046..7119)
                     /locus_tag="VVO77_002024"
     tRNA            complement(7046..7119)
                     /locus_tag="VVO77_002024"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7083..7085),aa:Asn,seq:gtt)
BASE COUNT         2251 a         1714 c         1125 g         2032 t
ORIGIN      
        1 taaaataaaa ataaataaaa tactgctttt cttcatacac tttctttcta aatgaagtat
       61 ttataattct acgactgtca tacttcctgt atcaacattg taaatggcac cagagataat
      121 gacatcgtct ggtattaggg gagactcgat aagcagttgc atatcctcgc gtacactctc
      181 ttctatatct tggaagggca agaagtcctg gtctgacaca tctacaccta attcctcttt
      241 taaatactcc tgaaaaggtt cattttcaaa ggtctgagca ccacagtctg tatggtgcaa
      301 taccacaatc tctcttgtcc ccatttgttg ctgggaaata actagcgaac gaatcatgtc
      361 ttcagtcact cgaccacctg cattccgcaa gatatgagca tccccaagtg ccaagcccag
      421 agcttgcgca acgtgcagac gagagtccat acaggtcaca atagctactc ttgttttggg
      481 tttaagtggc agatttaact gcccatgtag ggcaacataa gcctgattgg cttgcataaa
      541 ctgttcaaaa tacgacacga ttccctcctt gaaaatttga tagtcaaata tttctcctat
      601 cttatcattt ttaagagaat ttgtcacgga ttatgcaaag acctttttca agacttcctg
      661 aatcgttgtc acgccaatga cctgaatttc cttaggcaga gtgattcctg tcaaggaatt
      721 cttaggtaca taaatcttag taaagcccag tttagcagct tcgttgatgc gttgctcaat
      781 acgattcacg cgccgaatct ctcctgtcaa gcccagttct ccgacaaaac attcctgagg
      841 attagttggc ttgtctttgt agctcgaagc aatagcaact gcaacagcca agtcaatcgc
      901 aggttcatcc aatttaacac caccagcaga tttgagatag gcatcctgat tttgcaagag
      961 aagccctgcc cgtttttcca aaacagccat aatcaagcta gcacggttaa aatcaagtcc
     1021 tgtcgtagta cgcttggcat ttccaaacat ggtcggtgtt accaaagcct gaacctccgc
     1081 caaaatcgga cgcgtccctt ccatggttac aacgatggag gaaccagtcg ccccatccaa
     1141 acgctcttct aggaaaactt gactcggatt gagtacctca accaagccgc ccgactgcat
     1201 ctcaaaaatc ccaatctcat tagtggaacc aaaacgattt ttgaccgctc tcaaaatacg
     1261 aaaggtgtgg tgacgctccc cttcaaagta aagcaccgta tccaccatat gctccaacat
     1321 acgaggccca gccaaggttc cttctttggt cacatgacct acgataaaga tggcaatgtt
     1381 attggtcttg gccaactgca tgagttcagc ggtcacttca cgcacctgag aaacagaccc
     1441 ctgcacccct gaaatctcag gagacatgat ggtctggatg gaatcaataa tgagaaagtc
     1501 tggctggata cgctccactt ctgcacgaac actctgcata ttggtctctg catagagata
     1561 aaactcacta tcaatatcac ctaagcgctc tgcacgtagt ttaatctgct gggcagactc
     1621 ctccccactg acatagagaa ctgtccccac ttgggacaac tgggttgaga cttgtaggag
     1681 aagagttgat ttcccaatcc caggatcccc accgatgagg acgagacttc ctggtaccac
     1741 tccgcctcca agcacacggt tgaattcctc catctccgtc ttggttcgat tgacattgat
     1801 ggaagtcacc tcagctagtt tcatgggctt ggttttctca cctgtcaagg acacacgcgc
     1861 attcttgacc tcggcaacct caacctcttc cacaaaagaa gaccaagacc cacagttggg
     1921 gcaacgtccc agatatttag gggaattata cccacaattt tgacatacaa atgtcgcttt
     1981 tttctttgcg atgacaaacc tctttctata tctctaactc acactcaatc acttggcaaa
     2041 aatcaatctt ctcatttggc acaaactggc gcatgagcat tcgatgagca acaactacca
     2101 cagtctgatg ttctcgatac ttagacatac attctagaaa ccgagacttc atttccgtag
     2161 ctgtctcata ttgaatagga ctattaggaa gcaactcccc cttgttttct aaaaacagtc
     2221 ttctagctgt ttcaaaattt tctattcctg ttttatagac ctgccattca tgtaataaag
     2281 gctctactct taaaggaaga cccgtagcac agaccacata cgaagccgtt tctaaagctc
     2341 ttgtgactgc agaagatacg attatttcag ctgacgagag taaaggattt ttgctcaatt
     2401 tctggacttg ctgccgtccc atctcagaca agggtgccaa atctatccca aatcctatat
     2461 aagaacgctc ctctaactca cggtaatctg gctccccatg acgtacaaag ataatcttca
     2521 ttctagtgcc ctgtcgatcc aaatccacca gttcgaacgc catcagctgc atctccatct
     2581 gcaattaaga aagtagcaaa aacagcctgg acaatacgtt ccccaacttc aagaacaacc
     2641 tcttgatctg tgatattctt catctgcgca aaaatatgcc cttcatttcc aggatttcca
     2701 taataatccc catcaatgac cccaactgag ttaattaaaa ccaagccctt cttacgagga
     2761 tttgaagaac gatcatagag gtagagaacc tcagtcggct gcatataagc cttaacccct
     2821 gtcggaacca agacaatctc tcctggcgca acaactgtac gcacagcaac ctttaagtcg
     2881 taaccagccg catgcgctgt ctcacgcttg ggcaataaat tttcatctgt aaaactcgaa
     2941 accaattcaa aaccacgaat tttcataatt ttctcttttc tattatcatt tattctagat
     3001 tattctatct tatttattcg gaaaaagcac gaaaaaaaga gcacacaatt caaatcgctt
     3061 agggctgctg gattcctccc ctgacccgct tcacgcagaa ctgttgctcc actatttatt
     3121 atatcacatt cctattcatt ttaaaagcaa aattattttt tccgtctatt tctaaaaaaa
     3181 tcctgcatga tagctgcgca ttcatcttcc aaaattccta tttcaacctc cacacgatga
     3241 ttgagacgct catctgtcaa gatattgtac aaactcccag cagcgccaaa tttctggttt
     3301 ttagccccat agaccacatt tggaatgcgg gcaagcccaa tcgctccact acacatgaca
     3361 caaggttcaa tggtcacaaa aagtgtgcaa tccagcaagc gccagctctc ctcactcaag
     3421 ttcgcatcct ctatagccat aatttccgca tgcataaccg ctcgctgtaa ttcctcacgc
     3481 gcattatgcc cacgaccaat gatttcccca tctttgacaa tcacacaacc aattggaatt
     3541 tcatcgtgtt caagagcaat ctcagcctct ctcaaagcct ccctcataaa gacttctttt
     3601 tcttcaagcg tataatacat ctcttttctc ttttcctact tatcgatttt attattatat
     3661 catgaatccc aacacaaaaa aagccaccga atgcggtgac tctataggga gattattatg
     3721 aaaaagaaaa gtttaggata tttgttacaa caagttagga ggtcttcttg taaccgtcta
     3781 tagtataccc gacctatctt aaacaaatct taaaaatctc ttaggaccaa acactttcta
     3841 aaatatttgt ttgttcacga ccaggaccta ctgagaaagt agaaatacga acgccaacca
     3901 attcactcac acgacgaaca tagttacgcg cattctcagg aagatcttcc aaattgcgaa
     3961 ctccggtaat atcttctgac caacctggca actcttcata gataggcttg caacgtttca
     4021 attgctcaag actagctgga tagtagtcaa tacgttgacc gtcaagatca taggccacac
     4081 agattttcac agtatccaaa ccgctcaaaa catcaataga gttcaaagaa aggttagtaa
     4141 taccagaaac acgacggcta tgacgcatca caactgagtc aaaccaacct acacgacgtg
     4201 gacgaccagt tgttgtacca tactcatgac ccacttcacg gatacgttct cccacttcat
     4261 caaacaactc agttgggaaa ggaccatctc ctacacgact cgtataagct ttacatacac
     4321 ctacaacctt gtcaatcttg cttggaccga caccagaacc aattgtcaca ccaccagcta
     4381 cagggtttga tgacgtaaca aatggataag taccttggtc gatatctagc ataacacctt
     4441 gtgcaccttc aaaaagcaca cgtttgccat tatcaagcgc atcattcaag ataacagatg
     4501 tatctatcac gtatttcttg atttgttgac catattcgta atattcttca aaaatatcat
     4561 cgaaaacaat cgctttactg tcatacaatt tttcaaaaag acgattcttt tcagcaaggt
     4621 tacgttctaa acgctcacgg aaaatatctt tatctaaaag atctgcaata cgaattccaa
     4681 cacgagcagc cttgtccata taagctggac caattccctt aattgtcgta ccaatcttat
     4741 tgtcgccctt agcttcttct tgcaagcgat ccaactcgat atgataaggc aaaataacat
     4801 gcgcacgatc agaaatacgc aagttatcag ttgttacacc ttcctcatga agatagctca
     4861 actcttttac aagagattta ggatttacaa ccataccatt cccaatgaca gatatttttt
     4921 cagggaagaa aatcccagat ggaatcaagt gcaacttaaa tttcttaccg tcaatcacaa
     4981 tcgtgtgacc agcattatca ccaccttggt aacgtgcaat cacttctgca ttcgctgaaa
     5041 ggaagtctgt aatcttccct ttaccttcat caccccattg ggtacctaca acaacaactg
     5101 aagtcataat cttgtctgag ccctcaggct cttcctttct cacatacatg gcaggactct
     5161 cacctgcaat tatatcttac aatttattat aataaaaaat cgtcttttta tcaagaagaa
     5221 acaatagaaa gatttgctat ttccaactat taaaaaatga tttagaaaaa ttactagcta
     5281 tttactatca tctttccata aaagagtaaa ttagttcgga aatttactaa aattacctca
     5341 acaagaaata aaaccccgat tcattaccaa tttttcaaga tacaaacgat aagcaacacg
     5401 ataatggtaa acaataaaat ccttacgaca accaatgcca tatctcacta aataataaat
     5461 taaaaattta aaatgaacat gttcccagtc aaaattatca ccaaatgtag gaccatactc
     5521 ttcttcaata ctatcataga aattagccat ctgctcataa attttttgta acataatcaa
     5581 atactccttt tcttttttat aaacttattc taacaaaaaa ttttacacat tcactatcaa
     5641 ttcctgaatt gttaaaatac cagcctcaac aagataaaaa taggaaaagt tgacagaata
     5701 gaaacaaatt tgctacctaa atttcaaacg attaaagttc taaaaagacc gccttaaaac
     5761 ttttgggtaa atcctattag aactataata tttttatata ggtattatgg ttctgatttt
     5821 ctagtataaa aaattcaaac tagaattctt cttagaaaag gccgttttaa gtgctatcac
     5881 tgttcaaaaa tgagggtcgc tgaaacttct atcgtcaaga agaatcatca aattccttgt
     5941 atcatcaacc aaaagattgc tcagaagcta attaaaaaga cttctatgac cgacattgat
     6001 catcagttgt ctatttcaac ttcaactgtc attcgcaaga tcaatgattt tcactttgag
     6061 catgattttt cgcgtcttcc tgagattatg tcctaggacg ttgaaacagt ccggggagtg
     6121 actgtttcaa tcgggagatg gagatgagct ttattgctca agactttgat aagctcaata
     6181 tcataactgt tcttgagagc agaacacaag ccatcatccg aaatcccatg aatacaaggc
     6241 tatcaagcga tactgaaagc tcattcaaca agatagtcag aaactgagtg ataaacgatt
     6301 ttatcgccct acttttcgta tgcacttgac taataaagaa attctagata aacttttgag
     6361 ctattccgaa gacttgaaac accactataa tctctatcag ctcttgcttt tccacctctt
     6421 tttcagactc tgtttaaaac cttcctcaaa gataaagaga aaatcgtcaa cgcccttcaa
     6481 ttaccttatt ccaacgccaa actggaagcc accaataatc tcatcaaact tatcaagtac
     6541 aatgcctttg gttttaggaa ctttgaaaac ttcaaaaaag aaaggacgaa atttgtcctt
     6601 tctagatctt cgctttcttc aacccactac agttgacaaa gaaccgaaaa atgtctcgcc
     6661 tctaatatag tcaattgaaa caagaacaag acaaaagagc ctcataaaag gtattgcaac
     6721 ttgctaatac ctttttgggg ttctttttga tatgaaccca tgttttctca ataggattgt
     6781 actcaggtga gtagggagga agaggtaaaa gtttatgccc aaactcttca cacaagagtt
     6841 ctagcttacc cattctatgg aatcttgcat tgtccataat atagtagatt gaaactagaa
     6901 tagtacacct ctacttctaa aacattgtta gaattcgatt ttactgtcct gatcgatttg
     6961 tcctattctt atttcatttt actataacac gaaatagatt attattacat aacaaaaaag
     7021 aggtctaaac ctcttaacta aattactccg ccagtaggac tcgaacctac gacatcatga
     7081 ttaacagtca tgcgctacta ccaactgagc tatggcggat ta
//
LOCUS       DAVHLA010000071         6781 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVHLA010000071 DAVHLA010000000
VERSION     DAVHLA010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6781)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6781)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6781
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.071"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            <1..372
                     /locus_tag="VVO77_002025"
     CDS             <1..372
                     /locus_tag="VVO77_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEU5693977.1"
                     /translation="KVSGRRYQRISLVAGLTNGELIAPMTYEETMTSDFFEAWFQNFL
                     LPTLTTPSVIIMDNVRFHRMGKLELLCEEFGHKLLPLPPYSPEYNPIEKTWAHIKKHL
                     KKVLPSCNTFYEALLSCSCFN"
     gene            433..1395
                     /locus_tag="VVO77_002026"
     CDS             433..1395
                     /locus_tag="VVO77_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEU5693978.1"
                     /translation="MNMSNITIDGQEMDLSQTMPSYAQVVSLYEDTSISVSSNETDKV
                     LAGSLYTDTNEQGLMIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAEASKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRGVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVESLRYE"
     gene            1572..2579
                     /gene="gap"
                     /locus_tag="VVO77_002027"
     CDS             1572..2579
                     /gene="gap"
                     /locus_tag="VVO77_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEU5693979.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2647..3483)
                     /locus_tag="VVO77_002028"
     CDS             complement(2647..3483)
                     /locus_tag="VVO77_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU5693980.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVRWNEIVNPGD
                     VCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLAHCKLKTGRTHQIR
                     VHLLHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLERLTFTTLSNTFEKELKK
                     NG"
     gene            3609..5804
                     /locus_tag="VVO77_002029"
     CDS             3609..5804
                     /locus_tag="VVO77_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEU5693981.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIANHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYVMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5857..6009
                     /gene="rpmG"
                     /locus_tag="VVO77_002030"
     CDS             5857..6009
                     /gene="rpmG"
                     /locus_tag="VVO77_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU5693982.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            6019..6195
                     /gene="secE"
                     /locus_tag="VVO77_002031"
     CDS             6019..6195
                     /gene="secE"
                     /locus_tag="VVO77_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEU5693983.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6250..>6781
                     /gene="nusG"
                     /locus_tag="VVO77_002032"
     CDS             6250..>6781
                     /gene="nusG"
                     /locus_tag="VVO77_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEU5693984.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAE"
BASE COUNT         2103 a         1191 c         1469 g         2018 t
ORIGIN      
        1 aaagtatctg gaagaagata tcagaggatt tctttggttg caggtctaac aaatggtgaa
       61 ttaatcgctc caatgactta cgaagagacg atgacgagcg acttttttga agcttggttt
      121 cagaattttc tcttaccaac attaaccaca ccatcggtta ttattatgga taatgtaaga
      181 ttccatagaa tggggaagct agaactttta tgcgaagagt ttgggcataa actgttacct
      241 cttcctccct actcgcctga gtacaatcct attgagaaaa catgggctca tatcaaaaag
      301 cacctcaaaa aggtattacc aagttgcaat accttttacg aggctctttt gtcttgttct
      361 tgtttcaatt gactatagtt cacggataca gttgggaaag aagctattaa ttatttggag
      421 agtccttttg ggatgaacat gtcaaatatt actatagatg ggcaagaaat ggatctgagt
      481 caaacgatgc cttcttatgc tcaagtagtg agtctttatg aggatacaag catctctgtt
      541 agtagtaatg agacggacaa agtgttggct ggatccctct atactgatac aaatgaacag
      601 ggattaatga ttccaagcag tttactaaaa aattggaatg aacagacagg aaaaaatttg
      661 acagctaatg atcttattgg caaatcagtc tcagccagca ttgtagaaag tgctgccgaa
      721 gctagtaaga ttgctcaatt tcaaacgaag attgtacgtg taatcaatga tgaagatgac
      781 atggaggaca gcaacagttt catgctgtct catcaaatgg aaacgatttt gaaagaggct
      841 ggatttacga aagctgtatc ttattttatc ttggaactca aagatccatc acagacaaaa
      901 gtagtaacag aagaattaca gaaaaataag aagtatactg tgctttctca acagagagtt
      961 cttgatattg tgattacctt tattcgtgtt attcagggat tattgattgt gctttcatca
     1021 caagctattg tggtagcagc ggttatgatt ggtatcatta tttacatcaa tatcatgcaa
     1081 cgttccaagg aaataggtgt catgaaagca gttggttatc agaatcgtgg tgtcaaagga
     1141 atttttattt acgaggctat ctggattgta ggcatcgcct tgctgctggc atttttggtt
     1201 gcacaagggg tgggaagttt ggcgaatgcg attgtaagtc acttttaccc atccatcact
     1261 aaggtttttg aattaaatct tttatctgtt ttaggaactc tagttttcgc tctattactt
     1321 ggttatgtct cagcctactt cccggcgcgt aagattagta aaatggatcc tgtagaatcg
     1381 ttacgctatg aataataagg gattccttga tttacagtct taaaaagaaa ctcacataga
     1441 aaaacaatgg ccatacttgc aattcaactc aaatagttgt ataataggtt tgttgaaagg
     1501 tgatttgtag tgattcaagt tactcttttc acaataaaaa tttcatgatt ttcataagga
     1561 ggaaatcact aatggtagtt aaagttggta ttaacggttt cggacgtatc ggtcgtcttg
     1621 ctttccgtcg tatccaaaac gtagaaggtg ttgaagttac acgcatcaac gaccttacag
     1681 atccagttat gcttgcacac ttgttgaaat acgacacaac tcaaggtcgt ttcgacggta
     1741 ctgttgaagt taaagaaggt ggatttgaag ttaacggtaa attcatcaaa gtttctgctg
     1801 aacgtgatcc agaacaaatc gactgggcta ctgacggtgt agaaatcgtt cttgaagcta
     1861 ctggtttctt tgctaagaaa gaagcagctg aaaaacacct taaaggtgga gctaaaaaag
     1921 ttgttatcac tgctcctggt ggaaacgacg ttaaaacagt tgtattcaac actaaccacg
     1981 acgttcttga cggtactgaa acagttatct caggtgcttc atgtactaca aactgcttgg
     2041 ctccaatggc taaagctctt caagacaact ttggtgttgt tgaaggattg atgactacta
     2101 tccacgctta cactggtgac caaatgatcc ttgacggacc acaccgtggt ggtgaccttc
     2161 gccgtgctcg cgctggtgct gcaaacatcg ttcctaactc aactggtgct gcaaaagcta
     2221 tcggtcttgt aatcccagaa ttgaatggta aacttgatgg atctgcacaa cgcgttccaa
     2281 ctccaactgg atcagttact gaattggtag cagttcttga aaagaacgtt actgttgatg
     2341 aagtgaacgc agctatgaaa gcagcttcaa acgaatcata cggttacaca gaagatccaa
     2401 tcgtatcttc agatatcgta ggtatgtctt acggttcatt atttgacgca actcaaacta
     2461 aagttcttga cgttgacggt aaacaattgg ttaaagttgt atcatggtac gacaacgaaa
     2521 tgtcatacac tgcacaactt gttcgtactc ttgaatactt cgcaaagatt gctaaataat
     2581 tcttgagttg atagaaagca aggctttgtg gtcttgcttt tttatatgga aaaatggatg
     2641 acacgatcat ccattctttt ttaattcttt ttcaaatgta tttgaaaggg tagtgaaagt
     2701 tagcctctct aaagtaagtg ggtgggtaaa ggaaagtcgg aaggcatgaa gcataagccg
     2761 gcttgtcttt gatttactat tatagagagg gtctcccagg ataggaagat tatgatgcaa
     2821 aaggtgcaca cgaatctgat gggttcgccc tgtctttagc ttgcaatgag ccaaggaagt
     2881 cttgtttgag aattgcttta atctgcttac atgcgtttca gcatattgcc cattttttgc
     2941 atcaactatt ctttttctac gatcatggcg atcacgtcca attttgtctc tgaaaacaag
     3001 ttcttttctg ttgatatttc catcaactag agcccaatat tctctagaaa tctctttttt
     3061 ctccaataag cgattgagaa tgggcaggat aaaaggattt ttggcaaaga gaactaagcc
     3121 actggtttcc atgtccagac gatgaacgac atagcaggtt tggccaacat aggtactgac
     3181 atggttaaga agggcaattt cgtttggttg attaccatgc gttttcatcc cctctggttt
     3241 gtttacaata atcaagtgtt gatcttgata aacttcctgc actaagtctg ggttgcccca
     3301 agggatcgtc ttttggggat aatcttcctc gtcaaaagtc aactggcaaa catctccagg
     3361 atttacgatt tcgttccagc ggacttcttc ttgatttatc aaaatatgtt tcttgattct
     3421 caaaaaatga cggatttttc tagggatgag gagttgttcc tcaagtaatt gctttaccgt
     3481 catttgaggt agagaggcgg gtaatgtaaa tgtgaattgc atacagatat tgtaacaaaa
     3541 aaagccctat ttggatagga aatagctaaa ttcttgtctt cctatgatga agatgataaa
     3601 ataaacgcat gaaattagat aaattatttg agaaatttct ttctcttttt aaaaaagaaa
     3661 caagtgaact agaggactct gattctacta tcttacgtcg ctctcgtagt gatcgaaaaa
     3721 aattagccca agtaggtccg attcgaaaat tctggcgtcg ttatcatcta acaaagatta
     3781 tccttatact aggtttgagt gcaggcttgc tagttggaat ctatttgttt gctgtagcca
     3841 agtcgaccaa tgtcaatgat ttgcaaaatg ccttgaaaac tcggactctt atttttgacc
     3901 gtgaagaaaa agaggctggt gccttgtctg gtcaaaaggg aacctatgtt gagctgactg
     3961 acatcagtaa aaacttgcag aatgctgtta ttgcgacaga agaccgttct ttctataaaa
     4021 atgacgggat taactatggc cgtttcttct tggctattgt cactgctgga cgttcaggtg
     4081 gtggctctac cattacccaa cagctggcta aaaacgccta tttatcgcag gatcaaactg
     4141 ttgagagaaa agcgaaagaa tttttccttg ccttagaatt aagcaaaaaa tatagtaagg
     4201 agcaaattct aaccatgtac cttaacaacg cttattttgg aaatggtgtg tggggtgtag
     4261 aagatgcgag taagaaatac tttggagttt ctgcatcaga agtgagtctg gatcaagctg
     4321 cgactctggc agggatgctc aaggggccgg aactgtataa tcccttgaat tccgtagaag
     4381 attctactaa tcggcgcgat actgtcttgc agaatatggt tgcagcagga tatattgata
     4441 aaaaccaaga aaccgaagct gctgaagttg atatgacttc gcaattgcac gataagtatg
     4501 aaggaaaaat ctcagattac cgttacccct cttattttga tgcggtggtt aatgaagctg
     4561 tttccaagta taatctaaca gaggaagaga ttgtcaataa tggctaccgc atttacacag
     4621 agctggacca aaactaccaa gcaaatatgc agattgttta tgaaaacaca tcgctatttc
     4681 cgagggcaga ggatggaacg tttgctcaat caggaagtgt agctctcgaa ccgaaaacag
     4741 ggggagttcg tggagttgtc ggtcaagttg ctgacaatga taaaactgga ttccggaatt
     4801 tcaactatgc aacccaatca aagcgtagtc ctggttctac aattaagcct ttagttgttt
     4861 atacgccagc agttgaagca ggctgggctt tgaataagca gttggataac cataccatgc
     4921 agtatgacag ctataaggtt gataactatg cagggatcaa aacgagtcga gaagttccta
     4981 tgtatcaagc cttggcagaa tcgcttaatc tacctgctgt tgccactgtt aatgatttgg
     5041 gtgtcgacaa ggcttttgag gcaggcgaaa aattcggact caacatggaa aaggtcgacc
     5101 gtgttcttgg tgtcgccttg ggaagcggtg ttgaaaccaa ccctcttcaa atggctcaag
     5161 catacgctgc ctttgcaaat gaaggtttaa tgcctgaagc tcattttatt agtagaattg
     5221 aaaatgctag tggacaagtt attgcgaatc ataaaaattc acaaaaacgg gtgattgata
     5281 agtctgtagc tgacaagatg accagtatga tgttggggac tttcaccaac ggtaccggta
     5341 ttagttcatc gcctgcagac tatgtcatgg cagggaaaac tggaacaact gaagcagttt
     5401 tcaatccgga gtacacaagt gaccagtggg taattggtta tactccggat gtagtgatta
     5461 gccactggct tggctttccg accactgatg aaaatcacta tctagctggc tctacttcaa
     5521 acggtgcagc tcatgtcttt agaaacattg ccaataccat tttaccttat acgccaggaa
     5581 gtacctttac ggttgaaaat gcttataagc aaaatggaat tgcaccagcc aatacaaaaa
     5641 gacaagtaca aaccaatgat aatagccaga cagatgataa tttgtctgat attcgagggc
     5701 gtgcgcaaag tctagtagat gaggctagcc gggctatctc agatgcgaag attaaggaaa
     5761 aggctcaaac aatatgggat tcgatagtca atctatttcg ctaagatgct tgtcaaagcc
     5821 tagctttctt gttataatgg ataagatgga ggcgttatgg cactaaaaaa agcaagccta
     5881 gcttgtgcgg tttgtggttc gagaaactat tcaatcaaga tcagcggaaa ccccaagcct
     5941 acacgactag aagtaaataa attttgtaag cattgtggca agtacactac acacagagaa
     6001 acgagatagg agagagcgat gcgttttatt ggagatattt ttagacttct taaagacaca
     6061 acatggccaa ctcgcaagga aagctggaga gattttcgtt ctatcatgga atacacagct
     6121 ttctttgtag taattattta catttttgac cagttgattg tttcaggttt gattcgattt
     6181 attaacattt tttagaagat tagtggagtt aattacacta gaaatcttct atttatgaaa
     6241 ggaaatatca tggatagttt tgataaagga tggtttgttt tacaaactta ttctggttat
     6301 gaaaataagg tgaaagaaaa tctattacaa cgtgcacaaa cctacaatat gttggataat
     6361 attctacgcg ttgaaattcc aacacaaaca gtgcaagttg aaaaaaatgg aaagagaaaa
     6421 gaagtagaag aaaatcgctt tccaggttat gttcttgtag aaatggtcat gacagatgaa
     6481 gcttggtttg ttgttcgaaa cacaccaaat gttacaggat ttgtcggatc acacgggaac
     6541 agatcaaaac caactccatt attggaacaa gaaattcgtg acattttggt atctatggga
     6601 caaactgttc aagaatttga tttcgatgtt gagattggtc aaactgtacg tattattgat
     6661 ggtgcttttg cagactacac tggtaagatt acagaaattg ataataacaa agtgaaaatg
     6721 attatctcta tgtttggtaa tgacacagtt gcagaagtaa acctaaacca aatcgcagaa
     6781 t
//
LOCUS       DAVHLA010000072         6764 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVHLA010000072 DAVHLA010000000
VERSION     DAVHLA010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6764)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6764)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6764
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.072"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            1..412
                     /locus_tag="VVO77_002033"
                     /pseudo
     CDS             1..412
                     /locus_tag="VVO77_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
     gene            579..779
                     /locus_tag="VVO77_002034"
     CDS             579..779
                     /locus_tag="VVO77_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693985.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            821..1225
                     /locus_tag="VVO77_002035"
     CDS             821..1225
                     /locus_tag="VVO77_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693986.1"
                     /translation="MDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETNSVPA
                     GVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKAQNLL
                     QETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1456..2163
                     /gene="ccdA2"
                     /locus_tag="VVO77_002036"
     CDS             1456..2163
                     /gene="ccdA2"
                     /locus_tag="VVO77_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEU5693987.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDFNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            2174..2731
                     /gene="sdbB"
                     /locus_tag="VVO77_002037"
     CDS             2174..2731
                     /gene="sdbB"
                     /locus_tag="VVO77_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEU5693988.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIS
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            3105..4496
                     /locus_tag="VVO77_002038"
     CDS             3105..4496
                     /locus_tag="VVO77_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEU5693989.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKVPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4639..5556
                     /gene="adcAII"
                     /locus_tag="VVO77_002039"
     CDS             4639..5556
                     /gene="adcAII"
                     /locus_tag="VVO77_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEU5693990.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLAEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLEADPQNDKTYLENLEENMSVLAEELK"
     gene            5564..>6764
                     /gene="phtB"
                     /locus_tag="VVO77_002040"
     CDS             5564..>6764
                     /gene="phtB"
                     /locus_tag="VVO77_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HEU5693991.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRYQAGQDKKESNRVAYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVLKVNGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNEL
                     SASELAAAQAYWNGKQGSRPSSSSSYNANTAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLIFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEKRIA
                     RIIPLRYRSNHWVPDSRPEQPSPQSTPEPSPSLQPAPNPQPAPSNPIDEKLVKEAVRK
                     VGDGYVFE"
BASE COUNT         2074 a         1245 c         1426 g         2019 t
ORIGIN      
        1 gactgaaata gcttctgaat ttggctgtca tccaactacc atccactatg cgttcaaagc
       61 tatgggctac actcgaaaaa aagaaccaca cctactatga acaagaccca gaaaagtagc
      121 cttatttctt aagaatttta atagtttaaa gcacctagca cctgtttaga ttgatgaaac
      181 aggattcgat acttattttt atcgagaata tggtcgctca ttaaaaggtc agttaagaag
      241 aggcaaagta tctggaagaa gatatcagag gatttctttg gttgcaggtc taacaaatgg
      301 tgaattaatc gctccaatga cttacgaaga gatgatgacg agcgactttt ttgaagtatg
      361 gtttcagaag tttttcttac caacattaac cacaccatcg gttattatag taaaatgaaa
      421 taagaatagg acaaatcgat caggacagta aaatcgaatt ctaacaatgt tttagaagtc
      481 catatgtact attctagttt caatatacca taactgttcc tagtcaacct gcaagccctg
      541 tcccagctcc aagctcagct ccgactcaag atcctagagt ggtagcaagc gcttcggcta
      601 gctcaacgag cacacaagct caagagcaag ttgacaagtc tgaacttcgt gccttgagtc
      661 aagagttaga ccaacgcttg aaagctttgg caacagtatc tgatccgaaa atcgatgcaa
      721 ccaaggctgt cctcctagat gctcaaaaag ctccggaaga tagtgccttg acagagtaag
      781 gtctgcatac tgcagtagag tctgtgaagg ctgggctgcc ttggactctc tcaaagatgt
      841 gaaagcaaat gctagcgaca gcaagcctgc acaggacaag aaggatgcaa aacaaggaac
      901 ggaagatagt aaggattcag ataagatgac tgaaacaaac tcagttccgg caggagtgat
      961 tgtggtcagt ctacttgccc tcctaggcgt gattgccttc tggctgattc gccgtaagaa
     1021 agagtcagaa atccagcaat taagcacgga attgatcaag gttctaggac agctagatgc
     1081 agaaaaagcg gataaaaaag tccttgccaa agcccaaaac cttctccaag aaacccttga
     1141 tttcgtgaaa gaagaaaatg gctcagcaga gacagaaact aaactagtag aggagcttaa
     1201 agcaatcctt gacaaactca agtaaaacat gatttatgaa atgtcagacc taaaagacat
     1261 tttcgttcac aaaagcagcg atgagtaatc cttgtcgttg ctttttggct attttggggg
     1321 ataagatccg ccttgactag caaaagaaaa gattggtcca atagtgcccg atacgatttt
     1381 gcgtagcaga aagcttacaa ataaaattga atatagtaaa ataggattag aattattaag
     1441 aaagttggtt ctttattgga aacgatagta tttttaatct ctgtttttct agcaggtgtt
     1501 ttatcctttt tttctccttg tatttttcct cttctgccag tctatgctgg gattttattg
     1561 gatgatcaag aaagtgcaaa aagcttttct ttgtttggga gaaaggttct ctggtcaggc
     1621 ttgattcgaa cactttgctt tatcgctggt atctctctca ttttctttat tctaggcttt
     1681 ggtgctggtt actttggtca tattctctat gcaaattggt ttcgatatgt catgggagct
     1741 attattatca ttttgggtct tcaccagatg gaaatttttc atttgaagaa attagaagtt
     1801 caaaaaagtt ttacctttaa aaaatcagat tttaatcgtt attggtcagc ttttttactt
     1861 ggtattacct ttagctttgg ttggacacct tgtattggtc cagttttaag ttctgtttta
     1921 gcacttgcgg cttctggagg caatggtgct tggcaaggag cgatttatac tctcatttac
     1981 actctgggca tggcccttcc tttcttggtc ttggcactag cttcaggtct agtcatgcca
     2041 tattttagta aaatcaagcg tcatatgatg ctactaaaga aaattggtgg tttcctcatt
     2101 gttttaatgg gaattttgtt actattagga caagtaaatg ttctagctgg aatttttgaa
     2161 taaaggagga caaatgaaaa aagtaatgtt tgctggctta agtctcttgt cattagttgt
     2221 attgatggcc tgtggtgagg aagaaactaa aaagactcaa gcagcacaac agccaaaaca
     2281 acaaacgact gtacaacaaa tttctgttgg aaaagatgct ccagacttta cattgcaatc
     2341 catggatggc aaagaagtta agttatctga ttttaagggt aaaaaggttt acttgaagtt
     2401 ttgggcttca tggtgtggtc catgcaagaa aagtatgcca gagttgatgg aactagcggc
     2461 gaaaccagat cgtgatttcg aaattcttac tgtcattgca ccaggaattc aaggtgaaaa
     2521 aactgttgag caattcccac aatggttcca ggaacaagga tataaggata tcccagttct
     2581 ttatgatacc aaagcaacca ccttccaagc ttatcaaatt cgaagcattc ctacagaata
     2641 tttaattgat agccaaggaa agattggaaa gattcaattt ggtgctatca gtaatgcgga
     2701 tgcagaagca gcatttaaag aaatgaacta gaatcgataa aatctgatta caagatgtag
     2761 tcagattttg gtaacttcta aaactaactt ccagtttccc acaacctagc ttttagtatg
     2821 agaaaaacgc gtgacatcag tggaaatccg tcttagacta acttccactg gttttctttt
     2881 tcttgatata taagggttca aaagcgaaaa gactcagaaa aagtgcacga caaatagccc
     2941 taaaacagag tcgtcttaga gtaacttcca gttttgggag agagatggaa gttactttga
     3001 gaagttacgg tagtcagatt tttttagaaa aacattttat aaatattcac atatctccta
     3061 tatttatggt aaaatagaat tatcagttta ttttggagtc aaagatgaat atatttagaa
     3121 caaagaatgt tagtttagat aaaacagaga tgcataggca tttgaagtta tgggatttga
     3181 ttttgctggg tatcggagcc atggtaggga caggcgtctt tacaatcaca ggtactgcag
     3241 ctgcaacact tgctggccca gccctagtga tttcaatcgt tatttctgcc ttgtgtgtgg
     3301 gattatcagc cctctttttt gcagaatttg cctcgcgagt acccgctaca ggaggtgcct
     3361 atagttacct ctatgctatc ttaggagaat tccctgcctg gttggctggt tggttaacca
     3421 tgatggagtt catgacagcc atatcaggcg tagcttcggg ttgggcagct tattttaaag
     3481 gcttgctctc tcaatacggg atagcctttc ctcaggcttt aaatggtacc tttaatcctc
     3541 aagcagggac atttgttgat ttattgccta ttcttgtctt ggtcttggtg acttcgcttg
     3601 ttttactaaa tgccaaggca gccttacgct ttaattcgat tctagttatt ttgaaatttt
     3661 ccgctttagc tctctttgtt ttagtaggaa tttggaatat taagtttgat aattggagca
     3721 attttgctcc ttacggtttt ggacaaatct atggagctag tactggtatt atggctggtg
     3781 catccttgat gttcttcggt tttttgggat ttgaatccat ctctatggct gtagatgaag
     3841 tcaagactcc tcaaaaaaat attcctagag ggattgtctt atcgctttct atcgtaacca
     3901 ttctctatgc cttggtgacc cttgttttga ctggtgtggt tcactatagt catttaaatg
     3961 tcgatgatgc cgttgccttt gcccttcgta gtgttgggat tagttgggca gccaactatg
     4021 tgtcattagt ggctatcttg accttgatta cagtttgtat ttcgatgacc tatgccctat
     4081 cgcgtatgat ttacagttta gcacgtgacg gcttagtgcc tgctgccttt aaggaactga
     4141 cgaagactag caaggtacca aagaatgcta ctatcttgac aggtctagct tcagcagtag
     4201 cagcaggaat gttcccacta gccagtattg cagccttttt aaatatttgt accttagcct
     4261 acttgatcat gttggcttat ggtctgattc gcttacggaa agaaaaagga atgcccaaag
     4321 ctggggaatt taaaacacca ttggtacctc tgttaccaat tttatcgatc atcatttgtt
     4381 tatccttcat gttacagtat aatatgaata cctggattgc tttcctagtt gcgttgttag
     4441 taggaagtat tatttacttc acttatggct ataagcattc taccatagaa gaataaagtg
     4501 aaagtctatt gagttgttga cactcagcag atttttatat gtgaaagaaa tttcaaattt
     4561 tttctaaaaa tatcttgaca gattaaattt tcaggagtag aatatttact agttaattaa
     4621 atggttaagg agttgttcat gaagaaacaa aatttatttt tagtcctgtt aagtgtcttt
     4681 cttttgtgct tgggggcttg tggtcaaaag gaaagtcaga caggaaaggg gatgaaaatt
     4741 gtgaccagtt tttatcctat ctacgctatg gttaaggaag tatctggtga cttgaatgat
     4801 gttcggatga ttcagtcaag tagtggtatt cactcctttg aaccttcggc aaatgatatc
     4861 gcagccatct atgatgcaga tgtctttgtt taccattctc atacactcga atcttgggca
     4921 ggaagtctgg atcccaatct aaaaaaatcc aaagtgaagg tcttagaggc ttctgaggga
     4981 atgaccttgg aacgtgtccc tggactagag gatgtggaag caggggatgg agttgatgaa
     5041 aaaacgctct atgaccctca cacatggcta gatcctgaaa aagctggaga agaagcccaa
     5101 attatcgctg ataaactttc agaggtggat agtgagcata aagagactta tcaaaaaaat
     5161 gcgcaagcct ttatcaaaaa agctcaggaa ttgactaaga aattccaacc aaaatttgaa
     5221 aaagcgactc agaaaacatt tgtaacacaa catacagcct tttcttatct agcgaagaga
     5281 tttgggctta atcaacttgg tattgcaggc atctctcctg aacaagaacc aagtccacga
     5341 caattagcag aaattcagga atttgttaaa acctataagg ttaaaacgat ttttacagaa
     5401 agtaatgctt cttcaaaagt agctgaaact cttgtcaaat caacaggtgt gggtcttaaa
     5461 actctgaatc ctttagaggc agacccacaa aatgacaaga cctatttaga aaatctggaa
     5521 gaaaatatga gtgttctagc agaagaatta aagtgaggaa agaatgaaaa tcaataaaaa
     5581 atatctagca ggttcggtgg cagttcttgc cctaagtgtt tgttcctatg agcttggacg
     5641 ttaccaagct ggtcaggata agaaagagtc taatcgagtt gcttatatag atggtgatca
     5701 ggctggtcaa aaggcagaaa acttgacacc agatgaagtc agtaagaggg aggggatcaa
     5761 cgccgaacaa atcgtcatca agattacgga tcaaggttat gtgacctctc atggagacca
     5821 ttatcattac tataatggca aggtccctta tgatgccatc atcagtgaag agctcctcat
     5881 gaaagatccg aattatcagt tgaaggattc agacattgtc aatgaaatca agggtggtta
     5941 tgtccttaag gtaaacggta aatactatgt ttaccttaag gatgcagctc atgcggataa
     6001 tattcggaca aaagaagaga ttaaacgtca gaagcaggaa cgcagtcata atcataactc
     6061 aagagcagat aatgctgttg ctgcagccag agcccaagga cgttatacaa cggatgatgg
     6121 gtatatcttc aatgcatctg atatcattga agatacgggc gatgcctata tcgttcctca
     6181 cggcgaccat taccattaca ttcctaagaa tgagttatca gctagcgagt tagctgctgc
     6241 ccaagcctat tggaatggga agcagggatc tcgtccttct tcaagttcta gttataatgc
     6301 aaatacagct caaccaagat tgtcagagaa ccacaatctg actgtcactc caacttatca
     6361 tcaaaatcaa ggggaaaaca tttcaagcct tttacgtgaa ttgtatgcta aacccttatc
     6421 agaacgccat gtggaatctg atggccttat tttcgaccca gcgcaaatca caagtcgaac
     6481 cgccagaggt gtagctgtcc ctcatggtaa ccattaccac tttatccctt atgaacaaat
     6541 gtctgaattg gaaaaacgaa ttgctcgtat tattcccctt cgttatcgtt caaaccattg
     6601 ggtaccagat tcaagaccag aacaaccaag tccacaatcg actccggaac ctagtccaag
     6661 tctgcaacct gcaccaaatc ctcaaccagc tccaagcaat ccaattgatg agaaattggt
     6721 caaagaagct gttcgaaaag taggcgatgg ttatgtcttt gagg
//
LOCUS       DAVHLA010000073         6127 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVHLA010000073 DAVHLA010000000
VERSION     DAVHLA010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6127)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6127)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6127
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.073"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            281..1826
                     /locus_tag="VVO77_002041"
     rRNA            281..1826
                     /locus_tag="VVO77_002041"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1878..1950
                     /locus_tag="VVO77_002042"
     tRNA            1878..1950
                     /locus_tag="VVO77_002042"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1911..1913,aa:Ala,seq:tgc)
     gene            2075..4976
                     /locus_tag="VVO77_002043"
     rRNA            2075..4976
                     /locus_tag="VVO77_002043"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            5053..5168
                     /gene="rrf"
                     /locus_tag="VVO77_002044"
     rRNA            5053..5168
                     /gene="rrf"
                     /locus_tag="VVO77_002044"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            5173..5245
                     /locus_tag="VVO77_002045"
     tRNA            5173..5245
                     /locus_tag="VVO77_002045"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5206..5208,aa:Val,seq:tac)
     gene            5248..5320
                     /locus_tag="VVO77_002046"
     tRNA            5248..5320
                     /locus_tag="VVO77_002046"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5281..5283,aa:Asp,seq:gtc)
     gene            5345..5417
                     /locus_tag="VVO77_002047"
     tRNA            5345..5417
                     /locus_tag="VVO77_002047"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5378..5380,aa:Lys,seq:ttt)
     gene            5423..5504
                     /locus_tag="VVO77_002048"
     tRNA            5423..5504
                     /locus_tag="VVO77_002048"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5457..5459,aa:Leu,seq:tag)
     gene            5523..5595
                     /locus_tag="VVO77_002049"
     tRNA            5523..5595
                     /locus_tag="VVO77_002049"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5556..5558,aa:Thr,seq:tgt)
     gene            5618..5689
                     /locus_tag="VVO77_002050"
     tRNA            5618..5689
                     /locus_tag="VVO77_002050"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5650..5652,aa:Gly,seq:gcc)
     gene            5697..5782
                     /locus_tag="VVO77_002051"
     tRNA            5697..5782
                     /locus_tag="VVO77_002051"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5731..5733,aa:Leu,seq:taa)
     gene            5792..5865
                     /locus_tag="VVO77_002052"
     tRNA            5792..5865
                     /locus_tag="VVO77_002052"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5826..5828,aa:Arg,seq:acg)
     gene            5881..5954
                     /locus_tag="VVO77_002053"
     tRNA            5881..5954
                     /locus_tag="VVO77_002053"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5915..5917,aa:Pro,seq:tgg)
     gene            5960..6033
                     /locus_tag="VVO77_002054"
     tRNA            5960..6033
                     /locus_tag="VVO77_002054"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5994..5996,aa:Met,seq:cat)
     gene            6047..6120
                     /locus_tag="VVO77_002055"
     tRNA            6047..6120
                     /locus_tag="VVO77_002055"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6081..6083,aa:Ile,seq:cat)
BASE COUNT         1677 a         1264 c         1790 g         1396 t
ORIGIN      
        1 acacgggttc gaatcccgta cggactatgg tatgttgcgg ttggaacact tgatgaaaaa
       61 aagtttaaaa aaagcttaaa aatcttcaaa aaagtgttga caagtgaaag tggctgtgat
      121 atactaatat agttgtcgct tgagagaagc aagtgacaaa gacctttgaa aactgaacaa
      181 gacgaaccaa tgtgcagggc gctacaacat aagttgtagt actgaacaat gaaaaaaaca
      241 ataaatctgt cagtgacaga aatgagtaag aactcaaact tttaatgaga gtttgatcct
      301 ggctcaggac gaacgctggc ggcgtgccta atacatgcaa gtagaacgct gaaggaggag
      361 cttgcttctc tggatgagtt gcgaacgggt gagtaacgcg taggtaacct gcctggtagc
      421 gggggataac tattggaaac gatagctaat accgcataag agtggatgtt gcatgacatt
      481 tgcttaaaag gtgcacttgc atcactacca gatggacctg cgttgtatta gctagttggt
      541 ggggtaacgg ctcaccaagg cgacgataca tagccgacct gagagggtga tcggccacac
      601 tgggactgag acacggccca gactcctacg ggaggcagca gtagggaatc ttcggcaatg
      661 gacggaagtc tgaccgagca acgccgcgtg agtgaagaag gttttcggat cgtaaagctc
      721 tgttgtaaga gaagaacgag tgtgagagtg gaaagttcac actgtgacgg tatcttacca
      781 gaaagggacg gctaactacg tgccagcagc cgcggtaata cgtaggtccc gagcgttgtc
      841 cggatttatt gggcgtaaag cgagcgcagg cggttagata agtctgaagt taaaggctgt
      901 ggcttaacca tagtaggctt tggaaactgt ttaacttgag tgcaagaggg gagagtggaa
      961 ttccatgtgt agcggtgaaa tgcgtagata tatggaggaa caccggtggc gaaagcggct
     1021 ctctggcttg taactgacgc tgaggctcga aagcgtgggg agcaaacagg attagatacc
     1081 ctggtagtcc acgctgtaaa cgatgagtgc taggtgttag accctttccg gggtttagtg
     1141 ccgtagctaa cgcattaagc actccgcctg gggagtacga ccgcaaggtt gaaactcaaa
     1201 ggaattgacg ggggcccgca caagcggtgg agcatgtggt ttaattcgaa gcaacgcgaa
     1261 gaaccttacc aggtcttgac atccctctga ccgctctaga gatagagttt tccttcggga
     1321 cagaggtgac aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt tgggttaagt
     1381 cccgcaacga gcgcaacccc tattgttagt tgccatcatt cagttgggca ctctagcgag
     1441 actgccggta ataaaccgga ggaaggtggg gatgacgtca aatcatcatg ccccttatga
     1501 cctgggctac acacgtgcta caatggctgg tacaacgagt cgcaagccgg tgacggcaag
     1561 ctaatctctt aaagccagtc tcagttcgga ttgtaggctg caactcgcct acatgaagtc
     1621 ggaatcgcta gtaatcgcgg atcagcacgc cgcggtgaat acgttcccgg gccttgtaca
     1681 caccgcccgt cacaccacga gagtttgtaa cacccgaagt cggtgaggta accgtaagga
     1741 gccagccgcc taaggtggga tagatgattg gggtgaagtc gtaacaaggt agccgtatcg
     1801 gaaggtgcgg ctggatcacc tcctttctaa ggataaggaa ctgcgcattg gtcttgttta
     1861 gtcttgagag gtcttgtggg gccttagctc agctgggaga gcgcctgctt tgcacgcagg
     1921 aggtcagcgg ttcgatcccg ctaggctcca ttggtgagag atcaccaagt aatgcacatt
     1981 gaaaattgaa tatctatatc aaatagtaac aagaaaataa accgaaaacg ctgtagtatt
     2041 aataagagtt tatgactgaa aggtcagaaa ataaggttaa gttaataagg gcgcacggtg
     2101 gatgccttgg cactaggagc cgacgaagga cgtgacaaac gacgatatgc cttgggtagc
     2161 tgtaagtaag cgatgatcca gggatttccg aatgggggaa cccaacaggt aatacctgtt
     2221 acccacatct gttaaggatg tgaggaggaa gacgcagtga actgaaacat ctaagtagct
     2281 gcaggaagag aaagcaaaag cgattgcctt agtagcggcg agcgaaacgg cagaagggca
     2341 aaccgaagag tttactcttc ggggttgtag gactgcaatg tggactcaaa gattatagaa
     2401 gaatgatttg ggaagatcag ccaaagagag taatagcctc gtatttaaaa tagtctttgt
     2461 acctagcagt atcctgagta cggcgggaca cgtgaaatcc cgtcggaatc tgggaggacc
     2521 atctcccaac cctaaatact ccctagtgac cgatagtgaa ccagtaccgt gagggaaagg
     2581 tgaaaagcac cccgggaggg gagtgaaata gaacctgaaa ccgtgtgcct acaacaagtt
     2641 cgagcccgtt aatgggtgag agcgtgcctt ttgtagaatg aaccggcgag ttacgttatg
     2701 atgcgaggtt aagttgaaga gacggagccg tagggaaacc gagtctgaat agggcgcctt
     2761 agtatcatga cgtagacccg aaaccatgtg acctacccat gagcaggttg aaggtgcggt
     2821 aagacgcact ggaggaccga accagggcac gttgaaaagt gcttggatga cttgtgggta
     2881 gcggagaaat tccaaacgaa cttggagata gctggttctc tccgaaatag ctttagggct
     2941 agcgtcgaca ttagagattc ttggaggtag agcactgttt gggtgagggg tccatcccgg
     3001 attaccaatc tcagataaac tccgaatgcc aatgaattat ggtcggcagt cagactgcga
     3061 gtgctaagat ccgtagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
     3121 attgttaagt ggaaaaggat gtggggttgc acagacaact aggatgttag cttagaagca
     3181 gctattcatt caaagagtgc gtaatagctc actagtcgag tgaccctgcg ccgaaaatgt
     3241 accggggcta aaacaattta ccgaagctgt ggataccttt ataggtatgg taggagagcg
     3301 ttctatgtgt gatgaaggta taccgtgagg agtgctggaa cgcatagaag tgagaatgcc
     3361 ggtatgagta gcgaaagaca ggtgagaatc ctgtccaccg taagactaag gtttccaggg
     3421 gaaggctcgt ccgccctggg ttagtcggga cctaaggaga gaccgaaagg tgtatccgat
     3481 ggacaacagg ttgatattcc tgtactagag tatgtagtga tggagggacg cagtaggcta
     3541 actaaagcag acgattggaa gagtctgtct aagcagtgag gtgtgaattg agtcaaatgc
     3601 ttaattctat aacattgagc tgtgatgggg agcgaagttt agtagcgaag ttagtgacgt
     3661 cacactgcca agaaaagctt ctagcgttta aacatactct acccgtaccg caaaccgaca
     3721 caggtagtcg aggcgagtag cctcaggtga gcgagagaac tctcgttaag gaactcggca
     3781 aaatgacccc gtaacttcgg gagaaggggt gctgacttta agtcagccgc agtgaatagg
     3841 cccaagcaac tgtttatcaa aaacacagct ctctgctaaa tcgtaagatg atgtataggg
     3901 ggtgacgcct gcccggtgct ggaaggttaa gaggagtgct tagcgtaagc gaaggtatga
     3961 attgaagccc cagtaaacgg cggccgtaac tataacggtc ctaaggtagc gaaattcctt
     4021 gtcgggtaag ttccgacccg cacgaaaggc gtaatgattt gggcactgtc tcaacgagag
     4081 actcggtgaa attttagtac ctgtgaagat gcaggttacc cgcgacagga cggaaagacc
     4141 ccatggagct ttactgcagt ttgatattga gtgtctgtac cacatgtaca ggataggtag
     4201 gagtctaaga gatcgggacg ccagtttcga aggagacgct gttgggatac tacccttgtg
     4261 ttatggccac tctaacccag ataggtgatc cctatcggag acagtgtctg acgggcagtt
     4321 tgactggggc ggtcgcctcc taaaaggtaa cggaggcgcc caaaggttcc ctcagaatgg
     4381 ttggaaatca ttcgcagagt gtaaaggtat aagggagctt gactgcgaga gctacaactc
     4441 gagcagggac gaaagtcggg cttagtgatc cggtggttcc gtatggaagg gccatcgctc
     4501 aacggataaa agctaccctg gggataacag gcttatctcc cccaagagtt cacatcgacg
     4561 gggaggtttg gcacctcgat gtcggctcgt cgcatcctgg ggctgtagtc ggtcccaagg
     4621 gttgggctgt tcgcccatta aagcggcacg cgagctgggt tcagaacgtc gtgagacagt
     4681 tcggtcccta tccgtcgcgg gcgtaggaaa tttgagagga tctgctccta gtacgagagg
     4741 accagagtgg acttaccgct ggtgtaccag ttgtcttgcc aaaggcatcg ctgggtagct
     4801 atgtagggaa gggataaacg ctgaaagcat ctaagtgtga aacccacctc aagatgagat
     4861 ttcccatgat tatatatcag taagagccct gagagatgat caggtagata ggttagaagt
     4921 ggaagtgtgg cgacacatgt agcggactaa tactaatagc tcgaggactt atccaaagta
     4981 actgagaata tgaaagcgaa cggttttctt aaattgaata gatattcaat tttgagtagg
     5041 tattactcag agttaagtga cgatagccta ggagatacac ctgtacccat gccgaacaca
     5101 gaagttaagc cctagaacgc cggaagtagt tgggggttgc cccctgtgag atagggaagt
     5161 cgcttagctc tagggagttt agctcagctg ggagagcatc tgccttacaa gcagagggtc
     5221 agcggttcga tcccgttaac tcccaaaggt cccgtagtgt agcggttatc acgtcgccct
     5281 gtcacggcga agatcgcggg ttcgattccc gtcgggaccg tttaagataa cgcaagttat
     5341 tttagactcg ttagctcagt tggtagagca attgactttt aatcaatggg tcactggttc
     5401 gagcccagta cgggtcatat atgcgggttt ggcggaattg gcagacgcac cagatttagg
     5461 atctggcgct taacggcgtg ggggttcaag tcccttaacc cgcattaaga tataacaaat
     5521 gagccggctt agctcagttg gtagagcatc tgatttgtaa tcagagggtc gcgtgttcaa
     5581 gtcatgtagc cggcattttt agatagaaga aaacagtgcg aacgtagttc agtggtagaa
     5641 caccaccttg ccaaggtggg ggtcgcgggt tcgaatcccg tcgttcgctt agagaggccg
     5701 gggtggcgga actggcagac gcacaggact taaaatcctg cgattggtaa cgatcgtacc
     5761 ggttcgattc cggtcctcgg cataatatgg agcaccctta gctcaactgg atagagtacc
     5821 tgactacgaa tcaggcggtt agaggttcga ctcctctagg gtgcattttt ctttttaact
     5881 cgggaagtag ctcagcttgg tagagtactt ggtttgggac caaggtgtcg caggttcgaa
     5941 tcctgtcttc ccgattcatg gcggtgtagc tcagctggct agagcgtccg gttcataccc
     6001 gggaggtcgg gggttcgatc cccttcgccg ctataatgat cttgtcggac ctttagctca
     6061 gctggttaga gctctcggct cataaccgag tggtcgtagg ttcaagtcct acaaggtcca
     6121 tttgaat
//
LOCUS       DAVHLA010000074         5434 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVHLA010000074 DAVHLA010000000
VERSION     DAVHLA010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5434
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.074"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            121..816
                     /locus_tag="VVO77_002056"
     CDS             121..816
                     /locus_tag="VVO77_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001839244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase alpha helix C-terminal domain-containing
                     protein"
                     /protein_id="HEU5693992.1"
                     /translation="MTPEKNGSYKRNNSSLIYRDLIFLDYDDIQGTSEDFIEAVSSAL
                     FGYSYILYPTIKHSIEKPRFRLVVKSNNVMNEATYKQVVKEIADKIGLPFDMASLTWS
                     QLQGLPVTTGDPATYQKVVEHGLDYPVPKVEPRAKQGTTERYKPRVSGQRSMTMRIID
                     TLFNGFGDEGGRNVALTRFVGLLFNKWVDCDLETAYELTKIANSVTVEPLPIEELDRT
                     FSSIARAEYRKRG"
     gene            896..2350
                     /locus_tag="VVO77_002057"
     CDS             896..2350
                     /locus_tag="VVO77_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001828839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase family protein"
                     /protein_id="HEU5693993.1"
                     /translation="MWELYSRIWELGDQWRKENSYIVNEGKKNERVEIPRPSVAIVAK
                     ALQEICHFTFIGEGVISDISKLYLYHLDLGHYVSSNDIFRKLLLKYDSRLTSNKFFLE
                     LISYIRTETKMKPPLDDYRYIPVANGVYNIKTHKLEEFSPNFVITSKIQTEYNPCARK
                     PILDGWFDFDRWLEALAVNDKEVVALLWQVINEAINPNRTRKKMVLMVGDGNNGKGTF
                     QSLLENLIGRSNISNLKPDQFGKEFYLGALEGKVCNIGDDISNKYLDEVSDLMSVISG
                     DPVQVNKKSLQPVEARFRLLCIFSGNDLPRARNKTMGWYRRLCIIPFRADFNGQKERH
                     EIKDRFIKNKELLEWVLFKVLNMPDFDSFIEPEAVQKMLSKYKNDNDYIKVWVENFYI
                     PNGWHEINHVPMFIARNKLKEFAEDIGIDKPKLGQFSNAVMAELEKTTSYKYSAKNGT
                     VSSKFYDVLDPQGFQRKRFVKGIWGIHLEDEDLG"
     gene            2962..3135
                     /locus_tag="VVO77_002058"
     CDS             2962..3135
                     /locus_tag="VVO77_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein Cse60"
                     /protein_id="HEU5693994.1"
                     /translation="MKIKLFYQKYKQALWDLESQVNGFMADVEVIDVKYTKATVGNSE
                     DMDTLTSVMVLYK"
     gene            3152..3310
                     /locus_tag="VVO77_002059"
     CDS             3152..3310
                     /locus_tag="VVO77_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HEU5693995.1"
                     /translation="MEIQEGFIYFRNYGIIKLLEVPRFGSITLKIQDGEIVSSVESKT
                     TIFKKNTD"
     gene            3394..3993
                     /locus_tag="VVO77_002060"
     CDS             3394..3993
                     /locus_tag="VVO77_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693996.1"
                     /translation="MPTLQEVKNQMDKVRTQLEIFDRFDEEIKKAEQEVKAIKAKKAD
                     LQTFEDFQAINAKEKYIADMKAQRTKLEKERIDSIVADARKINASGYLETALEQDETV
                     KRQRQEIKQKSIELLELIANYNENYKNTAKRLADEVRETGIEELFDRLNTSPEYSGVS
                     KPYIYSGVAGYMGNQHRYLDPSDDLAYFVNRINLFEGEQ"
     gene            3993..4223
                     /locus_tag="VVO77_002061"
     CDS             3993..4223
                     /locus_tag="VVO77_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000650801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693997.1"
                     /translation="MKDEHKQLFQEIEEEKRQADLLQGLAKNVESISKSYEEEAVTLE
                     EFKAMGYKRRHELFEKDKALYDKLLGKEKRGL"
     gene            4287..4553
                     /locus_tag="VVO77_002062"
     CDS             4287..4553
                     /locus_tag="VVO77_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5693998.1"
                     /translation="MVRSSKARLEKLEEYAGKTEYATTDECISLYVDCLRFAFQQDEI
                     KIDMDDFIKTPFKDIKLADYKKSKKRMDELKEMTGISEFPELEQ"
     gene            4604..4945
                     /locus_tag="VVO77_002063"
     CDS             4604..4945
                     /locus_tag="VVO77_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000035041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HEU5693999.1"
                     /translation="MANYLMTGNVKKASELSEITRKTAYNYLNDATFKRIYRERRSEQ
                     LKESTTLLQNASVEAVNVLREIMLDKTVSPYARQQSAQSILNMAYKAVEMVEVVEQLE
                     ILEAKILDEGD"
     gene            4932..5183
                     /locus_tag="VVO77_002064"
     CDS             4932..5183
                     /locus_tag="VVO77_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000644292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694000.1"
                     /translation="MKAIKNRLNKLNKLSVVDEVDTVFLTQIDTGHFEVRYRIGGKNP
                     KDIIEGYPTKEEAEKAISEIKNTKGLRIFWDNLALLEDN"
BASE COUNT         1983 a          836 c         1188 g         1427 t
ORIGIN      
        1 ccatttgata agatggagcc gttccagtac attgaacgct ttaagccttt ggtagtccct
       61 gaaggggcaa acattgaaga atttaaacgt atacaagcgc cttactgtat tagtggcaaa
      121 gtgacaccag aaaagaatgg cagttacaag cgaaacaact ccagtctaat ctatcgggat
      181 ttgattttcc ttgattatga cgatatacag gggacgtctg aggacttcat agaagccgtt
      241 tctagcgctt tgtttggcta ctcttatatc ttatacccga ctatcaaaca tagcatagaa
      301 aagccccgtt ttcgccttgt ggtgaaatct aacaacgtga tgaacgaggc aacctataag
      361 caggtagtaa aagagattgc tgacaagatt gggctaccct ttgacatggc cagtttaacc
      421 tggtcacaac tccaagggct accagtcaca acaggcgacc cagcaactta tcaaaaggtt
      481 gtggagcatg gcctagatta tccagtcccc aaggttgaac caagagcgaa gcaaggaact
      541 actgagcgtt ataaacctag agtaagtggc cagaggtcaa tgactatgag gattattgac
      601 acgcttttca acggatttgg agacgaagga gggcgcaacg tagcgctgac acgctttgtg
      661 ggattactct tcaataagtg ggttgattgt gacctagaga cagcctatga acttacaaag
      721 atagccaata gtgtgacagt tgaaccattg cctattgagg agctagaccg cacttttagc
      781 agtatagcac gggctgagta tagaaagaga ggttagaacc atagaactag aagaattagc
      841 aaacctaaaa agtgaaatct tggaggtcag agagcaagaa caacctccta gaacgatgtg
      901 ggaactttat agtaggattt gggagcttgg ggatcaatgg cgtaaggaaa actcctatat
      961 cgtcaatgaa ggaaagaaaa acgaaagggt agaaatccca cgaccaagtg ttgcaatcgt
     1021 agccaaagcg ttacaggaaa tttgccattt tacctttata ggtgaggggg ttataagtga
     1081 tattagtaag ttatatcttt accatttgga tttaggccat tatgtatcaa gtaacgacat
     1141 tttccgaaaa ttgcttttaa aatatgactc acgtttgact tctaacaagt tctttttaga
     1201 acttatctcc tatatccgta cagaaactaa gatgaaacca ccgctggacg attatcgata
     1261 tattccagta gcgaatggag tttataatat taaaactcat aaactagagg aatttagtcc
     1321 taattttgtc attaccagta agatacaaac ggaatacaat ccatgcgcca gaaagcctat
     1381 tttagatggt tggtttgatt ttgatagatg gttagaggct ttagcagtta acgataaaga
     1441 agttgtagct ttattgtggc aagtcataaa tgaggctatc aatcccaacc gaacacgtaa
     1501 gaaaatggtg ctaatggttg gagatggtaa taatggaaag ggtactttcc aatccttgct
     1561 ggaaaattta ataggacggt caaatattag taatttgaaa cctgaccagt ttgggaaaga
     1621 gttctattta ggcgctttgg aaggaaaggt ttgtaatatt ggagatgata tttctaacaa
     1681 gtacctggat gaagtttctg accttatgag tgtaattagt ggagatccag tgcaggtcaa
     1741 taaaaaaagc ttgcaacccg tggaagcacg tttcagacta ttgtgtatct tttcgggtaa
     1801 cgatttgcct agagctagaa ataagaccat ggggtggtat agacggcttt gtatcattcc
     1861 tttccgtgca gattttaacg gtcagaaaga acgtcatgaa atcaaagacc gatttataaa
     1921 gaacaaagag ctgctagagt gggttttgtt taaagtttta aatatgccag attttgatag
     1981 ctttatagaa cctgaagcgg tacaaaaaat gcttagcaag tacaaaaacg ataacgatta
     2041 tatcaaagtt tgggtagaga atttctacat accaaacggg tggcatgaaa taaaccatgt
     2101 tccaatgttt attgcaagaa ataaattaaa agagtttgct gaggatatag gtatagataa
     2161 acctaaactt ggacaattta gcaatgcagt aatggccgaa ttggaaaaaa caacgtcata
     2221 taagtactca gccaaaaacg gaacggttag ctctaagttt tatgacgtac ttgacccaca
     2281 aggttttcaa cgtaaaagat ttgttaaagg tatatgggga atacacttag aagatgaaga
     2341 tttaggttag gaaatttaat actaaaaaac caattacacc aagggttata gcaatttagg
     2401 ttatgcaaaa aatagaaaca taacctaaac actaaccttt gtaaacgttg atataaaagt
     2461 ctttgcgagt atttaggtta gtaggttagt ttttatttct aatatctcta tataaaaaaa
     2521 taaatataaa cgtgttatat aggcgcgaac ttaaaaagta aaactaaccc taatctaaca
     2581 cccttgaaac gttgatatag taggcttttg aagggttatt ttttaaaact aatcaaaacc
     2641 taatctaata gaataaagga gcaaaacaga tggcgatgaa cattttgtca aagagtggct
     2701 agattagaag aaaccgttga gcggatcagt gaggcgctgg atggctttat tgagaatgcg
     2761 aaccataacg ctatagtaag caataaaaaa catcgaacgg attcaggaag gttttgaaat
     2821 agtctttaaa gagcttgatg aactaaaagc agtacctgac aaacactaaa acatttaaac
     2881 aaaatggggt agatagtacc gacccccttg caatggtgta actactagtg acaccctaaa
     2941 aacagaaaga ggagaaacaa catgaaaatt aaactatttt atcagaaata caagcaagcc
     3001 ctttgggatt tggaaagcca ggtaaatggt tttatggcag acgttgaagt tattgacgtg
     3061 aaatatacaa aggcaacagt ggggaatagt gaggatatgg atacactaac cagtgtgatg
     3121 gttctataca aataacatga aaggctaaaa tatggagata caagaaggct ttatttattt
     3181 tagaaattat ggtataataa aactgttaga ggttccaagg tttgggagta tcacgcttaa
     3241 aatacaagac ggtgagattg tctccagcgt ggaatctaaa acaacaatat ttaaaaagaa
     3301 tactgactga aaaaatcaga ggtatagcat aaagtagagt aatctatttt ggctatgcct
     3361 cttttgtttt tggaaagatt ggaggaaaaa gaaatgccaa cattgcaaga agtcaaaaac
     3421 cagatggaca aagtacggac tcaattagag atttttgatc gctttgatga ggaaatcaag
     3481 aaagcagagc aagaagttaa ggctattaaa gctaagaaag cggacttaca aacttttgaa
     3541 gattttcaag ctataaacgc aaaagaaaag tatattgctg atatgaaagc acaaagaact
     3601 aaactcgaaa aagaacgaat tgactcaatc gtggcagacg ctagaaaaat caatgcctca
     3661 ggttatttag aaacagcatt agagcaagat gaaacagtga aacgccaacg tcaagaaatc
     3721 aaacagaaat ctattgagct tctggagttg attgcaaatt ataacgaaaa ctacaaaaat
     3781 actgctaaaa gattggcgga tgaggtaaga gaaacaggta tcgaagagtt atttgaccgc
     3841 ctgaatacgt caccagaata tagtggagta agtaagcctt acatttacag tggtgtagct
     3901 ggttatatgg gaaaccaaca ccgctattta gatccgagtg atgatttagc gtattttgtg
     3961 aatcgtatca atttatttga aggagaacaa taatgaaaga tgaacataaa caactatttc
     4021 aagaaatcga agaagagaag agacaagctg acttactgca agggcttgcc aagaacgtag
     4081 aaagtatttc aaaatcttat gaagaggaag ctgtgaccct tgaagagttt aaagctatgg
     4141 gctacaagcg tagacatgaa ctatttgaga aagataaagc cctgtatgat aagctactag
     4201 gcaaggaaaa acgcggtttg taatgtggag gggagcaatc cccttttttt acataaatca
     4261 gacagaatta cacacgaggt aggggaatgg ttagaagttc aaaagcaaga ctagaaaagt
     4321 tagaagagta tgctggaaag acggaatatg caacaactga tgaatgtata tctttatatg
     4381 tggattgttt aagatttgct tttcagcaag atgaaataaa gatagatatg gatgatttta
     4441 ttaaaacacc atttaaagat attaagctag cagactataa gaaatcaaaa aaacgtatgg
     4501 atgaacttaa ggaaatgact gggataagtg agtttccaga attagagcaa taaagcgagg
     4561 tgaacagtat ttgacagaat taagcagaaa aaaagaaata tttatggcca attatctcat
     4621 gactgggaat gtaaaaaaag ctagtgaatt aagtgagatc accagaaaga cggcttacaa
     4681 ttacttgaac gatgcaacct ttaagagaat ttaccgtgaa agacggagcg aacaacttaa
     4741 ggagtctact acgctgttac agaatgcaag cgttgaggca gtcaatgtat taagggaaat
     4801 catgcttgat aagacagtga gcccgtatgc gagacaacaa agcgcccaaa gcattctaaa
     4861 catggcttat aaggcggttg aaatggttga ggtagtggag caattagaaa tattagaggc
     4921 gaagatacta gatgaaggcg attaaaaacc gtttaaataa gttgaataag ttatcggtgg
     4981 ttgatgaagt tgataccgtg tttttgacgc agattgatac tggacatttt gaggtaagat
     5041 ataggatagg tggaaaaaat cccaaagata ttatagaagg ctatccgaca aaagaagaag
     5101 cagaaaaagc tatttcagaa attaaaaata caaaaggatt gcggatattc tgggacaatt
     5161 tggctttatt ggaggataat tagagcttat catttatcaa gcagataaga gaaataataa
     5221 ccctccttaa ctccttgaga aacgacaagc agataagcga agtttttagc cctcttattt
     5281 cggttctact ccttgcagaa tgacaaggaa ataagagaga taaaaacatc ccttaattgc
     5341 ttatcaaacc acaaggagat acgggggcta tctccctccc cacgcacttc tatgagcttc
     5401 acaccgtcat tgtacatttt ttctcacggg gaag
//
LOCUS       DAVHLA010000075         5329 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVHLA010000075 DAVHLA010000000
VERSION     DAVHLA010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5329
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.075"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            <1..803
                     /locus_tag="VVO77_002065"
     CDS             <1..803
                     /locus_tag="VVO77_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU5694001.1"
                     /translation="LLSDPNREQFQHDNRQVDLKILARHIHRLKKKQSDWKVQYTRCL
                     DIIFPELDKIVGKHSEYTYQLLTRYPNPQKRIEAGFDKLIEIKRLTASKIQDILSVAP
                     RSIGTTSPAREFEIIEIIKHYKRLIDKAETCVNDLMAEFNSVITTVTGIGGRLGAVIL
                     AEIRNIHAFDNPAQLQAFAGLDSSIYQSGQIDLAGRMIKRGSPHLRWALIQAAKACAR
                     FSPAFKAYLKTKLEQGKHYNVAIIHLAKKLIRTLFYILKKSCHLTNKK"
     gene            complement(1002..2891)
                     /locus_tag="VVO77_002066"
     CDS             complement(1002..2891)
                     /locus_tag="VVO77_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEU5694002.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWSRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSRFERDCLNLAFSGKKEATLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGLEKTLQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            3029..4594
                     /locus_tag="VVO77_002067"
     CDS             3029..4594
                     /locus_tag="VVO77_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEU5694003.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            4594..>5329
                     /locus_tag="VVO77_002068"
     CDS             4594..>5329
                     /locus_tag="VVO77_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU5694004.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEEIAKENLEKVGMGERYWQARPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYL"
BASE COUNT         1649 a         1216 c          990 g         1474 t
ORIGIN      
        1 aacttctttc tgaccccaat cgtgaacaat ttcaacacga taatcggcaa gtagacctaa
       61 aaatactggc tagacatatt catcgtctca agaaaaaaca gtctgattgg aaagtacaat
      121 acactcgttg tcttgatatc atctttcctg agttggataa aatcgttgga aagcattcag
      181 aatataccta ccaactcttg acgcgctacc ctaatcctca gaaaaggatt gaggcaggat
      241 ttgataagct gatagaaatt aagcgattga ccgcttctaa aattcaggat atcctctcag
      301 tcgcacctcg ttctatcgga acaacatctc ctgctcgtga attcgaaatc atcgaaatca
      361 tcaaacatta caagaggctc attgacaagg cggaaacatg tgtcaatgac ttgatggctg
      421 agttcaactc agtcatcacg acggttactg ggattggggg tcgtttaggg gcggtcattt
      481 tagccgagat tcgaaatatt catgcctttg ataatcctgc tcaattacaa gctttcgctg
      541 gactggattc ttctatttat cagtcaggtc agattgattt agctggaaga atgatcaaac
      601 ggggttcccc tcatctgcgg tgggcactca tacaagctgc caaagcatgc gctcgctttt
      661 cacctgcttt taaggcctat cttaagacta agttagaaca aggaaaacat tacaatgtag
      721 ccatcatcca ccttgcaaaa aaacttatcc gaaccctgtt ttatatccta aaaaagagct
      781 gccatttgac gaacaaaaag tgatgtaatt tctgaaatta acacaggatt acctttgaaa
      841 aaatggactt tttcaagggc tttttgccgt gctctaaaat catcgccaaa tcatcaaatt
      901 gaaataagaa atagtttaga taaaactatt gacttttctt atagtttgtc tttcttctat
      961 cttccattat atcatacttt ttcagtctat ggtagctctc tttaaaaggc tccgatactg
     1021 ccgccacctc cgcctccaga gaagccaccg ccagaacttc cacttccaga agatacggag
     1081 taggtacttg ctgtatttgc gacactagca taatggctca tttgcgcgct tgaatgataa
     1141 aacatactgt gccagccata agctacatag agattgatat ctggattttc aacttgaatc
     1201 tgatgaacct tcatcaaatg actaaccttg tccgcatagc caaataaggt tgcatagacc
     1261 aagagacgat tccaaacaac aatactttcc aattcagcct tatccagtcg tgcaatctca
     1321 cgtaacatat tttcaaaact ggtccagaga tagtagacct cagctcccgc ttcatttaga
     1381 acaccatcac gattatctag tcgaagcttc caataataga aaacagacaa aactaaccct
     1441 agaaaaccaa gtattggcaa agggaggtaa agatagccat gaacgtctaa actgtacaag
     1501 aacaaaccaa atccgataaa taggggcaag atagtcaaga cacccatacc cacttgcaaa
     1561 gtcttttcca aaccagttaa aggacgatag taatctggga gcccccagaa ggaaactcgt
     1621 tttctcactc cttcttgcat ctggttcaat acctcttcaa aagaagattt gagttgaagc
     1681 cctcttgctt gaatccgttt ttcatcagaa actttggctc tacgataaag actatcagat
     1741 accttgtaat ccgcaaacaa attggaaaga gtggcttctt ttttgcctga aaaggctaga
     1801 tttagacagt ctctctcaaa tcttgacaaa ccatcttctt tcaccaatct caagccaact
     1861 gcatctcctt ctgaaataat agagacattc ccacggtcta tcacatctag caaggtagct
     1921 tgaataagtt gatcaaaggt gaattttcca gctcccttga ccaagggact cacttcctcc
     1981 aaggaggtcg agtagactgc ttctgataaa accataggct ctaattccat tggtggttca
     2041 tagagacgat gatttttggc atatttgact gaaggagtgg tctttcttct ataaataaaa
     2101 tagaagcaga cactcaataa caaggagatg gaaaggatcg aagggaggac ccaagtaacg
     2161 agttgtttac tctgatcttt ttctctaaca atcgagtctt ctatcttatt aaactcttct
     2221 aaacgattcc ctttcaagcc ctgatcccta gcgctagcaa aatcggtccg agaccaatag
     2281 gcatgcaact caactccacg cttagccgga agattgtcta aacggatagt ataatcaagg
     2341 ttactctttt caatcgttcc ctctctaaaa agtttccctg tatggaaaaa gagtttttca
     2401 gcccccttgt ctccccttac atgaaattca aacttttcaa tagactctga actatctgtc
     2461 agaggttgcc aatttaattc agcgatatca tcataaagga aaagtaaatt ttttaagttc
     2521 cagacgaggt caacttcaac tatgtcgccc tcctgacctg gattatagac tctcacagta
     2581 taaccatccg cttcttctgt tacttcgcta gtcacatctg ctagttctgc accgtttttc
     2641 gcagcctgaa cctttggatg agggtcaatg tcaaacccgc taggcatctt accagcacgt
     2701 ccaagtccca cgatttggcc cttaaagtcc tcctcaaact ggtaaactat cttctgtcta
     2761 aactctgccg tattatctgc atgaatatac aaatcccctt gataagagtt tatcttgaaa
     2821 tcaatggcaa aaacagagag tggaagaagg caaaacaagc ctaacaccag taagaaaaaa
     2881 gtttttttca tcaactaagc ccccttttta tctttcttat cattatagca ttttttcgta
     2941 agtaaaggct tacttatgtt gaaaaattac gcatttttcg ataaaatagg agacagttat
     3001 tttttaatag atcagaatag gagaaatcat gagaaaaata tacttatcta ttttcacaag
     3061 tctcttgctg atgctaggac ttgtcaatgt tgctcaagcc gatgaatatt tacgcatcgg
     3121 gatggaagca gcatatgctc cctttaactg gacccaggat gatgatagca acggagctgt
     3181 caaaatcgat gggaccaatc agtatgccaa cggatacgat gttcaaatcg ccaagaaaat
     3241 cgctaaggac ttaggtaaag aacctttggt tgttaaaacc aagtgggaag gtctagtccc
     3301 tgcccttact tctggtaaga ttgacatgat tatcgcaggt atgagtccaa ctgcagaacg
     3361 caaacaagaa attgcctttt cgagcagtta ctacactagc gaaccagttt tgcttgtcaa
     3421 aaaagattct gcctacgcaa gtgctaaatc tttggatgac tttaacggtg caaaaatcac
     3481 ttctcaacaa ggggtctacc tctacgactt gattgcacaa atcccaggtg ctaaaaaaga
     3541 aacagccatg ggagacttcg ctcaaatgcg acaagctctt gaggctggtg tcattgatgc
     3601 ttatgtttct gaacgtccag aagcactgac tgctgaagct gcgaactcta agttcaagat
     3661 gattcaagta gaacctggtt tcaaaactgg ggaagaagat acagctatcg ctatcgggct
     3721 tcgtaaaaat gacaatcgta ttagccaaat caatgccagc attgaaacca tttcaaagga
     3781 cgaccaagtt gccctgatgg atcgtatgat caaggaacaa cctgccgaag ctacaacaac
     3841 tgaagagact agcagtagtt tctttagcca agtcgctaaa attctttctg aaaactggca
     3901 acaactcttg cgtggtgctg gtatcactct tttaatctct atcgtcggaa ccatcatagg
     3961 tctcattatt ggacttgcca ttggtgtctt ccgtactgct cctctctctg aaaacaaagc
     4021 catttatggc cttcaaaaac tagtcggctg ggttctcaat gtctacattg aaattttccg
     4081 tggtacgcca atgattgttc aatcgatggt tatctactat ggaactgccc aagctttcgg
     4141 gatcaacctt gaccgtacac tggctgctat cttcatcgtt tcaatcaata ccggtgccta
     4201 catgactgaa atcgtccgtg gtggtatcct agcagttgac aagggacaat ttgaagctgc
     4261 gactgctctt ggtatgaccc ataaccagac catgcgtaag attgtcctac ctcaggtagt
     4321 ccgtaacatc ctacctgcaa ctggtaatga atttgtcatc aatatcaaag atacatctgt
     4381 attgaacgtt atctctgttg tcgaacttta tttctcagga aataccgtgg caacacaaac
     4441 ctatcaatac ttccagacat ttacaatcat cgccgtgatt tactttgtcc tcaccttcac
     4501 cgtaacacgt atcctacgct ttatcgagcg cagaatggac atggatacct acactacagg
     4561 tgctaaccaa atgcaaacgg aggatttgaa ataatgacac aagcaatcct tgaaattaaa
     4621 cacctcaaaa aatcctatgg acaaaacgaa gtgctaaaag acatttctct cactgtccac
     4681 aagggagaag ttatttctat catcggaagc tctggaagtg ggaaatcaac cttcctacgc
     4741 tccattaacc tacttgaaac gccaactgat ggacaaatcc tttatcatgg acaaaacgtc
     4801 ctcgaaaaag gctatgacct cacgcaatac cgtgaaaagt tagggatggt tttccaatcc
     4861 tttaacctct ttgaaaatct caacgttctt gaaaacacaa tcgtcgctca gacaactgtc
     4921 cttaaacgcg aacgcacaga agctgaagaa attgccaaag aaaacctgga aaaggtcggc
     4981 atgggagaac gctactggca agcgagaccc aaacaactct caggtggtca aaaacaacgt
     5041 gtggccatcg ctcgtgccct ttcaatgaat cctgacgcca ttctctttga tgaaccaaca
     5101 tcagctctcg atccagaaat ggttggagag gtcctcaaaa tcatgcaaga tctggctcag
     5161 gaaggcttga ccatgattgt cgtaacccat gaaatggaat ttgcccgtga tgtctctcac
     5221 cgtgttatct ttatggataa gggtgtgatt gctgaagaag gtaaaccaga agacctcttc
     5281 actaatccta aagaagaccg tacaaaagaa tttcttcaac gttatctca
//
LOCUS       DAVHLA010000076         5282 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVHLA010000076 DAVHLA010000000
VERSION     DAVHLA010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5282
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.076"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(<1..2450)
                     /locus_tag="VVO77_002069"
     CDS             complement(<1..2450)
                     /locus_tag="VVO77_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RICH domain-containing protein"
                     /protein_id="HEU5694005.1"
                     /translation="MFASKSERKVHYSIRKFSIGAASVVVASLFLGGVVHAEGVRSKN
                     NLTVTSSGQDISKKYADEVESHLQSILKDVNKNLKKVQHTQNVDFNKKLSRIKTKYLY
                     GLKEKSEAELTLKTKETKEELTAAFEQFKKDTLKSGKKVAEAEKKAKAQKEEDRRNYP
                     TNTYKTIELEIAEAEVGVAKAELELEFAQAQVQIPQDTEKINAAKSKVEAAKSNVKKL
                     EKIKSDIEKTYLYKLDNSTKETPKPRVRRNSPEIKAKGRVKNYEEANIELSKYMTDLY
                     KLDNSTKETPKSRVRRNSPQVGDSRELKETIDKAKETLSTYMVTRLTKLDPSVFWFAD
                     LLMDAKKVVEEYKTKLEDASDKKSVEDLRKEAEGKIESLIVTHQNREKENQPAPQPGG
                     QAGGSMVVPPVTQTPPSTSQSPGQKATEAEKKKLQDLIRQFQEALNKLDDETKTVPDG
                     AKLTGEAGKAYNETRTYAKEVVDKSKKLLSQTAVTMDELAMQLTKLNDAMSKLKEAKA
                     KLVPEVKPQPENPEPKPQPEGEKPSVPDINQEKEKAKLAIATYMSKILDDIKKHHLKK
                     EKHHQIVALIKDLDKLKKQALSEIDNVNTKVEIENTVHKVFADMDTVVTKFQKGLIQN
                     TPQVPEAPKSPEVPKVSDTPKAPDTPQVPEAPKSPEVPKVPEAPKAPDTPQVPEAPKS
                     PEVPKVPDTPKAPDTPQVPEAPKSPEVPKVPDTPKAPDTPQVPEAPKSPEVPKVPDTP
                     KAPDTPQVPEAPKAPDTPQIPEAPAPETPAPAPEAPKTGWKQENGMWYFYNTDGSMAT
                     GWLEYNGSWYYLNANGAMA"
     gene            complement(2529..3056)
                     /locus_tag="VVO77_002070"
     CDS             complement(2529..3056)
                     /locus_tag="VVO77_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEU5694006.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYMTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            complement(3139..4470)
                     /gene="hk06"
                     /locus_tag="VVO77_002071"
     CDS             complement(3139..4470)
                     /gene="hk06"
                     /locus_tag="VVO77_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEU5694007.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIYE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            complement(4467..5120)
                     /gene="rr06"
                     /locus_tag="VVO77_002072"
     CDS             complement(4467..5120)
                     /gene="rr06"
                     /locus_tag="VVO77_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEU5694008.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDEITQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
BASE COUNT         1426 a         1104 c          862 g         1890 t
ORIGIN      
        1 gccatagcac cattagcgtt gagatagtac catgagccat tgtattctag ccagcctgtt
       61 gccattgaac catcagtatt gtagaagtac cacataccgt tttcttgttt ccagcctgtt
      121 tttggagctt ctggagctgg agccggagtt tctggagctg gtgcttccgg aatttgcggt
      181 gtgtctggag cctttggtgc ttctggaacc tgcggtgtgt ccggagcctt tggtgtatct
      241 ggaacctttg gtacctctgg gctctttggt gcttctggaa cttgcggtgt gtccggagcc
      301 tttggtgtat ctggaacctt tggtacctct gggctctttg gtgcttccgg aacttgcggt
      361 gtgtctggag cctttggtgt atctggaacc tttggtacct ctgggctctt tggtgcttcc
      421 ggaacttgcg gtgtgtctgg agcctttggt gcttctggaa cctttggtac ctctgggctc
      481 tttggtgctt ctggaacctg cggtgtgtcc ggagcctttg gtgtatctga aacctttggt
      541 acctctgggc tctttggtgc ttctggaacc tgcggtgtgt tctgaattaa gcctttttgg
      601 aatttagtaa caaccgtatc catgtctgca aataccttgt ggactgtatt ctcaatttct
      661 actttggtat ttacattatc aatttcagaa agtgcttgct ttttaagttt atcaaggtcc
      721 ttaataagag caacaatctg atgatgtttt tctttcttca gatgatgttt ctttatatca
      781 tctaaaatct tgctcatgta tgttgctata gcaagtttag ctttttcttt ctcctgatta
      841 atatctggta cgcttggttt ctcaccctct ggttgtggtt ttggctctgg gttttccggc
      901 tgtggtttaa cctctggtac caatttcgct ttagcttctt tcaatttaga catggcatcg
      961 ttcaatttgg ttaattgcat tgccaattca tccattgtca ctgctgtctg tgatagaagc
     1021 ttcttgcttt tgtcaacaac ttctttcgca taagttctag tctcattata ggcttttcca
     1081 gcttctcctg tgagtttagc cccatctgga acagtctttg tttcatcgtc tagtttgttc
     1141 aaggcttctt ggaattgacg aatcaagtct tgtaactttt tcttttcagc ttcggtcgcc
     1201 ttttgtcctg gactttggga agttgatgga ggtgtttgcg tcaccggtgg tacaaccatt
     1261 gaaccacctg cttgtcctcc tggttggggt gctggttggt tttctttttc tctattttgg
     1321 tgagtcacga taagagactc tatttttcct tctgcttcct ttcgcaagtc ttctaccgat
     1381 tttttatctg aagcatcctc taattttgtc ttgtattctt ccacaacctt cttagcatcc
     1441 ataagaagat ctgcaaacca aaaaacagat ggatccagct tcgttaaacg agttaccata
     1501 taggtagaca gagtttcttt cgctttgtct atcgtttcct taagttctct cgaatcgcct
     1561 acttgcggag aatttcttcg cactctagat tttggcgttt ctttggttga gttatctaat
     1621 ttatacaaat cagtcatata tttagaaagt tcaatattag cctcttcata atttttgact
     1681 ctgcccttag cttttatttc cggagaattt cttcgcactc taggttttgg cgtttctttg
     1741 gttgagttat ctaatttata caaatacgtt ttttcaatat ctgatttaat tttttctagt
     1801 tttttaacat tacttttagc agcttctact ttagatttag cagcattaat tttctcagta
     1861 tcttgaggta tttgaacttg agcttgtgca aactcaagct caagctctgc cttggcgacc
     1921 cctacttctg cttccgcaat ttccagttcg attgttttgt aagtattggt tgggtagtta
     1981 cggcgatctt cttctttttg agctttggct tttttctcag cttctgctac cttttttcct
     2041 gatttcaatg tatctttttt aaactgctca aaagctgcgg ttaactcttc ttttgtttct
     2101 tttgttttta acgtcaactc agcttccgac ttctctttta atccatacaa atacttcgtt
     2161 ttaattctgc tcaacttttt gttgaagtcg acattttggg tatgttgaac ttttttcaaa
     2221 tttttattga catccttcaa tatactttgt agatgcgact cgacttcatc agcatacttc
     2281 ttcgatatat cttgcccact agatgtaacc gtgaggttat tcttactcct aaccccttct
     2341 gcatggacta ctcctcctaa gaacaagctg gcaactacta cactagctgc tccaatacta
     2401 aatttacgaa ttgaataatg tacttttctt tcgctttttg atgcaaacat gtttatttcc
     2461 ttctatattt tttctttaac cttactatat cacttcaata tgaactgtat atgagtcgaa
     2521 ttttgtattt atctctttat gcttccattt gggattataa cttcatgtaa tagcttttcc
     2581 tcttcagcta ttcgtcgata caaaataact gcataaactg gaaaaactaa aacaaaagtc
     2641 atataggcat gactcaacaa ggtcaagcca atcaactcag gtaaaatatt taaaaagtaa
     2701 ttagggtgtt ttactgtcct aaacaagata tgatctacat atttgtgatt attgacaagc
     2761 ataagcttca ctgtccaaat atctcccaac aagtgaatca ccaacatcaa catcagcata
     2821 gaaaaaataa gcaagactaa accaaccatg cccatgccat caaaaattgt cttgtgcacc
     2881 attgcctcaa ccaagcaaga gagataaaaa acaatatgag ccatagttaa tcgttttgta
     2941 ttctcaactc caaattcttt cccgccattg ctaaggattc gtttctcatt ctctatcgaa
     3001 cgctttaaaa aaatcaatcg aataaagaat gttactaaaa taatcgctaa taccatatta
     3061 gtatcctttc ttttatctac acaaagaata acacacttat gttaacccta tatgaacttt
     3121 aataaaaaac taatctgtct acaagctaat cttaaattcc ataccgtgtt cataagggag
     3181 aaaactataa tccatttgat agctttctaa aatattattc acaatgtaaa gacccaaacc
     3241 ggaactttca tccttatctg tcacgatttg agaatgataa aatatatcaa ataaatgttc
     3301 tagttcttgg tcacttagag gcgcacatgt atttttgata gagagatagc catcttgctc
     3361 ggatatgatt acgcgcccat ttttatctga atatttaatt gcattactaa tcaggtttgt
     3421 caaaacctta tccaatgccc taagactcat gacgactctg gtagcatctg tcaattgatt
     3481 ttcaattgta acacctattg aatgagctaa ttcttgataa cgtgataaaa tatctactaa
     3541 aactggctta acagtcaaag tctcacgaca ctctgtccac tcttggaatt tagaagactc
     3601 cagtacttct tccaataagt ggctcatctg gtcaatctta tttatactct ttgcaatata
     3661 ttttggatga tctttgtaat ctccaatatt atgctgcata ttctctagga taattctaag
     3721 actggctaaa ggggttttca actcatgtga tgctccgcgg acaaaggaaa ccttttgatt
     3781 ttgcaatttt acaatttgct cattacgact ttccaactca taaataacct tcaacaagtg
     3841 ctcatacata ccattaatct gttttccaac ttcaccaact tcatctttcc tactttcatc
     3901 aaaacgaata ttgtcatcca aatcttgcat tttactagtc acttctgaaa tgtaaaaaag
     3961 aggattgagc aagcgtttag tataaaaata agaaaaaaca aaggaaaaag caattgtaac
     4021 caaaaatgta tatgggagat acaaaagcaa aatattcttt gcttctttgt agacatccac
     4081 cccgtgaaca aattgcactg ttacctgttt accatctgct gtactaacag acatatctaa
     4141 catcacgata taatttgata gctttccatc tttaatatcc aagtcatgca caagagggag
     4201 ccgcttatct acaatatctc ttttaaggtg agcagatatg gtcaaggact ttgaataaga
     4261 ctggagtaag cttggaattt catcagatgt cttagtcttt aaatactccg taaacactct
     4321 tgcgctctca ttaaactttt ccccctccag ttgaatataa taaaaaggaa aggtcaaata
     4381 aatagctata tgaatgacta gaccaacacc acctagaatt gcaaaacttc ttaaaaagga
     4441 cttggttaat aatttaggat tttttatcat aaactaatct tatacccaac atttttcaca
     4501 gtcacgatac aatctaaagc taattttttg cgaagagtac gaatatagac atcaacgacc
     4561 ctatcacaag gtaaatcagc tacatctttt gaaatttctt ccaatatctg ctctctactt
     4621 aaaacttgat ttttatgctg aatcaaacac tttagtacca gtaattcctt tggtttgaga
     4681 tcaatttctt catttttata atgtgctttg taagaggtaa aatccactgt tacatcctga
     4741 tatcgccaaa tatcctctat gacgtagtaa cgtctgataa gcgccttaat acgcttgaca
     4801 agcagtacca aagaaaaagg ttttgtcaca tgatcatcag catagagatc aaatacctgt
     4861 gactgagtaa tttcatctcc cagagcactc aagacgatga caggaatatc gtgcttttga
     4921 ttgatttctt ttaacacttc aaaaccactc ttcctaggca tcattaaatc cagtaccatg
     4981 agatggatag ggagatcttg aaatttttcc aagacctctt gtccatcctt agccataatg
     5041 acatgataac cctcttctgt cagaaatgct gcaattcctt ctctaatcat ttcctcgtca
     5101 tctgcaacta aaatgttcat ctctctccct ttctactacc agaactccat acatctattt
     5161 cctgtatgct atttgaaaat ttcctaccag cctatcatct atgataatag aatggatttc
     5221 atttatccgc tactttttgt caacaacaac gtcaatacaa gaaaatcatt catcttgcag
     5281 ct
//
LOCUS       DAVHLA010000077         5264 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVHLA010000077 DAVHLA010000000
VERSION     DAVHLA010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5264)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5264)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5264
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.077"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(17..379)
                     /locus_tag="VVO77_002073"
     CDS             complement(17..379)
                     /locus_tag="VVO77_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU5694009.1"
                     /translation="MQYIIRNTHGNYTSLNNAYAQDKRLKATTIGILTVILMNKSDWV
                     VYPDEIARRLGISRRTVDEHFKLLEKAGYLRVYRLGLGRGKGVTVYRFFSDMPISDDY
                     FEYLKTNLEKELSTDNGV"
     gene            complement(422..649)
                     /locus_tag="VVO77_002074"
     CDS             complement(422..649)
                     /locus_tag="VVO77_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU5694010.1"
                     /translation="MPKMTLRAIRTNYNLSAKEVADKLNIHQQTLLKYEHDSSKIPMD
                     LLDKLARLYNVEKDFIFLGKKYELNHNLGEV"
     gene            722..928
                     /locus_tag="VVO77_002075"
     CDS             722..928
                     /locus_tag="VVO77_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694011.1"
                     /translation="MTDYQLEASLIVLGKEFDRTKKNGKESFSVHVSFFDGLDANQHL
                     QEFARQYPVKIDRSNSDQITFLIK"
     gene            complement(1153..1323)
                     /locus_tag="VVO77_002076"
     CDS             complement(1153..1323)
                     /locus_tag="VVO77_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694012.1"
                     /translation="MKEKLNEFLKFRSQFTKREWFEINQAVEACLNEKADQLKLDDSD
                     VEIISKRLGRSI"
     gene            1522..1971
                     /locus_tag="VVO77_002077"
     CDS             1522..1971
                     /locus_tag="VVO77_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001058907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694013.1"
                     /translation="MNNFSFIETLAIAAIPAFVSGMWSYIAAKGNSKHEIDKINIAHS
                     QELENVENQFKQDMEKMQKQHSQELYSLQQTHELRLLELEKVSQLDTQTDQGLKINDL
                     IFKAISGEISADVAIKNMSTLSHFANKQQPSDLQKQFVKKLSKKNHK"
     gene            complement(1962..2129)
                     /locus_tag="VVO77_002078"
     CDS             complement(1962..2129)
                     /locus_tag="VVO77_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001005822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694014.1"
                     /translation="MNESFLTILGISMIASFITNLIAYLAGKHHLKKKIKNHKMWFDS
                     EIERIKKKYHL"
     gene            complement(2204..2479)
                     /locus_tag="VVO77_002079"
     CDS             complement(2204..2479)
                     /locus_tag="VVO77_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015973618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694015.1"
                     /translation="MNTLNEKAINIFKAVAKETLIQGTYEENFLYSQLEAFCTNCRQF
                     AFGWTELAEEIERQERYLLDSGFTQEEIDDIRFDAAFAGMLDKLNVA"
     gene            2652..3443
                     /locus_tag="VVO77_002080"
     CDS             2652..3443
                     /locus_tag="VVO77_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LexA family transcriptional regulator"
                     /protein_id="HEU5694016.1"
                     /translation="MARGRGKLTPQDKEDMKVFSANLNSILSDRNCKQAELSRATGIP
                     PSTLTGYVKGTSLPIPGNVQKIADFFGVPKSVLDPRFITNNFMVNDSSSNTPQIQTIY
                     DELEPPRQGKVLNYAKRQLKEQKNEEETKINEVSEAIRLYSYDYYDHPASAGTGQYLN
                     DVRVERIELPVDVDADFVIPIKGDSMEPDYHDGDLVFIQTSVDLNDGVIGVFNYNGDA
                     YIKQLVIDEDQAYLHSLNPEYKDMPITPDTDFRIIGEVVDLYREK"
     gene            3445..3645
                     /locus_tag="VVO77_002081"
     CDS             3445..3645
                     /locus_tag="VVO77_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694017.1"
                     /translation="MSNESRPMEVIKHNLDCKCHRRREWIRVNDKWHAIEFSVDDPNE
                     PPMTEEEKANVALILQQHLSKE"
     gene            3813..5240
                     /locus_tag="VVO77_002082"
     CDS             3813..5240
                     /locus_tag="VVO77_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEU5694018.1"
                     /translation="MKTTNKVAIYVRVSTTSQVEEGYSIDEQKDKLEAYCKIKDWKIY
                     DVYVDGGFSGANTQRPELERLISDVKRKKVDIVLVYKLDRLSRSQKDTLFLIEDVFAK
                     NDVAFISLQENFDTSTPFGKASIGMLSVFAQLEREQIKERMMLGKEGRAKNGKSMSWT
                     TIPFGYDYSKETGVLSVNPTQALIVNRIFTEYLNGKPVVKIIRDLNAEGHVGRKRPWG
                     ETITKYLLKNETYLGKVKYKDKVYEGQHEPIITQELFDLVQLEVERRQISAYEKYNNP
                     RPFRAKYMLSGLMKCGYCGASLGLRYTRKDKNGISHHKYQCRNRHSKDLEKRCESGWY
                     SKEELERGVIKELERIKFDPKYKNETLAKKEETIKVEEIKKQLERINNQVSKLTELYL
                     DEIITRKELDEKNDKIKTERQFLEEQLENQKSNVLSIRKRKLTRLLKDFDVEKLSYED
                     ASKIVKNIIKEIIVTKDGMSITLDF"
BASE COUNT         1752 a          992 c          969 g         1551 t
ORIGIN      
        1 ttttccaact gtatttttaa actccgttat ctgtggataa ctctttctca agattagttt
       61 ttagatactc aaagtaatca tctgaaatag gcatatctga aaaaaatcta tataccgtta
      121 cgcctttacc tctgcctaac cctaagcgat atactctgag atagcctgct ttctctaaaa
      181 gcttaaagtg ctcatctacg gtgcgcctgc ttattcctag acgtcgtgca atctcgtcag
      241 gatacacaac ccaatcagac ttattcatca agattactgt aaggatacct atcgttgttg
      301 cctttaaacg tttgtcttga gcataagcat tattcaaaga tgtgtaattc ccatgagtat
      361 tcctgattat atactgcata cctcatattt aatccccttt ctataactct cgctcgttca
      421 ttcacacctc tcctagatta tgatttaatt cgtatttttt gcctaaaaaa ataaaatcct
      481 tttcaacatt gtatagtcga gcaagtttat ctaaaagatc cattggaatt tttgaactat
      541 catgctcata cttcaacagt gtttgttgat gaatgttaag tttatcggca acttcttttg
      601 cagataagtt ataatttgtt cttattgctc tcaatgtcat tttcggcacg ttcctacctc
      661 cttatttttc tatttgttcc tcgcaattct gctataataa agctagaaag gaggtgatgt
      721 tatgactgat tatcaattag aagcttctct aattgtcctt ggcaaagaat ttgatagaac
      781 caagaaaaac ggaaaagaaa gttttagtgt tcatgtttct ttttttgatg gtttagatgc
      841 taatcagcat cttcaagagt ttgcacgaca atatcccgta aagattgacc gttcgaactc
      901 tgaccaaata acttttctaa taaagtaata tcgtttagag ggaagggatt ggtttcaact
      961 ctatcgttaa acgttaaaac aacttcacac ttctccagat aatgattggt aaattccact
     1021 cgctcaactc cgtcgagaaa cattccatcg acgaatacag cagggtggtt ttttcttgcc
     1081 gtcaacaata catcatgctc tgatgtattt actgatatag ttctgttaga cgccatttgt
     1141 ttgacccttt ctttagatag accgtcctag tcttttagaa atgatttcta catctgagtc
     1201 gtccagtttc aactggtcgg ctttttcatt taaacaagct tcgacagctt ggttgatttc
     1261 aaaccattct cgttttgtaa attggcttct gaattttaga aattcgttta gtttttcttt
     1321 cataccctcg tcctactttc cattgccctg agttctatct catgactgac ttgaagaaat
     1381 agcttctcac acgctatttt agcttctctg tacgttgtgt tttcgctgat gaagtaatca
     1441 gcaagttcaa tgattttatc ttccaattct aactaccttt caaatgtggt ataatcaaaa
     1501 taaaatgatt ggagaaatct tatgaataat tttagtttta tagaaacact tgcgatcgct
     1561 gccatacctg cctttgtttc tggcatgtgg tcttacatcg ctgctaaagg aaacagcaag
     1621 catgaaattg ataaaattaa cattgcacac tcacaagagc ttgaaaatgt cgaaaatcaa
     1681 tttaaacaag atatggaaaa aatgcaaaag caacactcac aagaacttta ttcgctgcaa
     1741 caaactcacg aattaagatt acttgaactt gaaaaagtat ctcaactaga cactcaaacc
     1801 gaccaaggct taaagataaa tgacctaatt tttaaagcta tttcaggaga aatatctgca
     1861 gatgtagcaa taaaaaatat gagcactctt agtcatttcg cgaacaagca acaaccttcc
     1921 gatcttcaaa aacaatttgt gaaaaaatta tccaagaaaa atcacaaatg atactttttc
     1981 ttgatacgct ctatctcaga atcaaaccac attttgtggt ttttaatttt ctttttcaga
     2041 tgatgcttac cagctaagta agcaattaaa ttcgtgataa aactagcaat cattgatatg
     2101 cctagtatcg taagaaaaga ttcattcatc gttctactcc tttctctctt ttttcgctct
     2161 atgagcaaca acctgccaag gattcgaacc ttggtgatac caatcaggct acatttaatt
     2221 tatcaagcat tcctgcaaat gctgcatcaa aacgaatgtc atcgatttcc tcttgagtga
     2281 aaccagaatc gagaaggtaa cgctcttgac gttcaatctc ctctgctaac tctgtccatc
     2341 caaaagcgaa ttgacggcag ttagtacaga atgcttcaag ctggctgtaa aggaagtttt
     2401 cctcgtaagt gccttggatt aaagtttcct tagctactgc tttaaagatg ttgattgctt
     2461 tctcgtttaa tgtgttcatg gtgtttccct ccggtttgtt tttgttattt ccttaagctt
     2521 gattatatta tactacgatt taaatcgtat gtcaatgatt tttcgaattt tttcgtaatt
     2581 ttttcgaatt ttttatttac aaaatcgaaa ataaacggta ttatatagta aagaagatag
     2641 gaggtaaaaa tatggcaaga ggacgaggga aattaactcc tcaagataaa gaggatatga
     2701 aagtcttttc tgcaaatctt aactcaattt tatctgatag aaattgtaaa caagctgagc
     2761 tgtctcgagc aacaggaata ccgcctagta cattgacagg gtatgtaaaa ggaacttctt
     2821 tgccaatccc tggtaatgtt caaaaaattg cagatttttt tggagttcct aaatctgtat
     2881 tagatcctag atttataact aataatttca tggtcaatga ctcttcttct aatactcccc
     2941 aaattcaaac catctacgac gaactagaac cacctagaca gggcaaagtc ctgaattatg
     3001 caaagaggca actgaaagag caaaaaaacg aagaagaaac gaagataaac gaagtatcag
     3061 aagctattcg gctctacagt tacgactact acgaccaccc agcttccgca ggtacaggcc
     3121 agtatttgaa tgatgtacga gtggaacgga ttgagttacc agtagatgtt gatgctgact
     3181 ttgtcatccc catcaaaggt gactccatgg agcctgacta ccacgatggt gacctggtat
     3241 tcattcagac aagtgtagat ttgaatgacg gagttatcgg agtattcaac tacaacggcg
     3301 atgcttatat caagcagctt gttattgatg aagaccaggc ttacctacat agcctaaacc
     3361 ctgaatataa agatatgcca attacaccag acaccgactt ccgaattatc ggcgaagtcg
     3421 tggatttgta tagggagaaa taacatgagt aacgaaagta gaccgatgga agtgattaaa
     3481 cacaacctag attgcaaatg ccacagacga agagagtgga ttagagtaaa tgataaatgg
     3541 catgctatcg agttttcggt agacgatcca aacgaacctc ctatgacaga ggaagagaaa
     3601 gccaacgtgg ccttaattct tcaacaacac ttatcgaaag aataaaacca actgtttcca
     3661 aaatggaaat aattgcaaac aaaaaaagcc ccacgctctc aaagtttggc gactccgagc
     3721 gtgaggctag tggcaagaaa aacttttcaa aagatattac cttttgagac gttttcttgt
     3781 acctatttta tcaaaaaagg ggtacaaatt caatgaaaac aacgaataaa gtcgcaatct
     3841 acgtcagggt gtccactact tcgcaggtgg aagagggtta ctctatcgat gagcagaaag
     3901 acaagcttga agcctactgt aaaatcaaag actggaaaat ctacgatgtc tacgttgatg
     3961 gtggtttctc aggtgctaac actcaaagac ctgaattgga gcgtttaatc tcagacgtga
     4021 agcgcaagaa agtcgatata gtgctagtct acaagctaga ccgcctcagt cgtagccaga
     4081 aagatactct gtttctgatt gaagatgtgt ttgctaaaaa cgatgtggca tttatcagct
     4141 tgcaagaaaa ctttgacact tctacgcctt tcggcaaggc ttcaatcggt atgctatcag
     4201 tattcgctca gctggagcgt gagcagatta aagagcgtat gatgttagga aaagaaggac
     4261 gggcaaagaa tggaaaatcc atgtcatgga cgacaatacc attcggctat gattactcaa
     4321 aagaaactgg cgtcttatca gtgaatccga cccaagcgct cattgtcaac cgtattttca
     4381 cggaatactt gaacggtaag ccagtagtca agatcatcag agacttaaat gctgaaggtc
     4441 acgttggaag aaaaagacct tggggcgaaa caatcacgaa atacttgctg aaaaatgaaa
     4501 cctatttggg aaaagtaaag tacaaagata aggtatacga ggggcagcat gaaccaatta
     4561 tcactcaaga attgtttgac ttagtccagc ttgaagtcga aagaaggcag atttcagcct
     4621 atgaaaaata taacaatcca aggccgttca gggcaaagta tatgctttct ggattaatga
     4681 aatgcggata ttgtggtgct tcacttggtc tgagatatac aagaaaagac aagaatggaa
     4741 tctctcatca taaataccaa tgcaggaacc gacacagcaa agatttagaa aaaagatgcg
     4801 aatcagggtg gtactctaaa gaggaacttg aaaggggtgt aatcaaggaa cttgaaagaa
     4861 ttaaatttga tccaaaatat aaaaatgaga cactcgctaa gaaagaagag actatcaagg
     4921 tcgaggagat aaagaaacaa ctcgaacgga taaataatca agtctcaaaa ttaacagaat
     4981 tgtacttgga cgaaatcatc actcggaaag agttggacga gaaaaatgat aaaatcaaaa
     5041 cagaaaggca attcctggaa gaacagctcg aaaatcaaaa atcgaatgtt ctgagcatcc
     5101 gaaagagaaa gctaacacgg ctactaaagg acttcgatgt tgaaaaatta agctacgaag
     5161 atgcttcaaa aattgtcaaa aatatcataa aagaaattat tgttacaaaa gacggcatgt
     5221 cgataacgct agatttttaa agggtctagc gtatttctgt attt
//
LOCUS       DAVHLA010000078         4949 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVHLA010000078 DAVHLA010000000
VERSION     DAVHLA010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4949)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4949)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4949
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.078"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            77..439
                     /locus_tag="VVO77_002083"
     CDS             77..439
                     /locus_tag="VVO77_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HEU5694019.1"
                     /translation="MLEVGLNFLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKKISVTVIGYFEINIDENITDILYVNGTAILYHYLRSIVSIVSAIDSSEAMLL
                     PTINVLELLDKSQPFEEE"
     gene            1484..2476
                     /locus_tag="VVO77_002084"
     CDS             1484..2476
                     /locus_tag="VVO77_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU5694020.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPNSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            2478..3296
                     /locus_tag="VVO77_002085"
     CDS             2478..3296
                     /locus_tag="VVO77_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEU5694021.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            3298..4083
                     /locus_tag="VVO77_002086"
     CDS             3298..4083
                     /locus_tag="VVO77_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU5694022.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            4181..4399
                     /locus_tag="VVO77_002087"
     CDS             4181..4399
                     /locus_tag="VVO77_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEU5694023.1"
                     /translation="MKDLPEWFGIPESTQAYIEGTTTLQVWTAYQESDLTGFVRLSYS
                     SEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            4384..4581
                     /locus_tag="VVO77_002088"
     CDS             4384..4581
                     /locus_tag="VVO77_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU5694024.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEASNKDYDRTNDFYRGLGFKKL
                     EIFSQLWNPQNPCQILIKKLE"
BASE COUNT         1418 a          817 c         1038 g         1676 t
ORIGIN      
        1 aacttcaaaa cagtgttttg agcaacctgc ggctagtttc ctagtttgct ctttggtttt
       61 cattgagtat aacagattgt tagaagttgg tttaaatttc ctaatcagtt tgttcacatt
      121 taccttcgat atattatatc ccatagttaa ggttggtcat acagatgatt atagtcatgg
      181 agccgtaaaa cttagtgttt ctttagttga caaagatgcc atgaaaaaaa tatctgtaac
      241 tgtaatagga tattttgaaa taaatataga tgaaaatatc accgatattc tatacgtaaa
      301 tggtactgct attctttatc attatttacg ttctattgtt tcaatagttt cggcaattga
      361 tagcagtgaa gcaatgttgc tacctaccat taatgtttta gagttactag ataaatctca
      421 accttttgaa gaagaataat ttattagctc actaaattga gggtaaggaa aagtaaaatc
      481 agtaagaaaa atgtcttgca ttatacagca accttttggg aatgagtaga tggattgaat
      541 aaaattttat taagagtgga tgatttatct gtagattatt attggacagt tagtcttgaa
      601 gtagtctaag aattaggtta taatcagtag aatccttgct aataatgagg aggttagttt
      661 atgtatagta gactgaatct aaaatagtac gaaacaattg ctaaaacatt tatagaaatt
      721 aattttactt tcccaatcga tttgttctca tcttatttca atccgctata tattatggta
      781 tcgaatcttc atcagaatga taaaattaat caattgatat ctgattacaa acagaatatg
      841 aaagcttttt atatcactat tgaaaaattt atacgagatg atgaaagcct taagtgttat
      901 tttataaagg ttatttcaag tcgttccaag gtaacaagtc tagatcagat tgaagctgat
      961 aaaacgatac aaagaaaata ttcaagtgag ctaaaaaaat ttattggatt ttataatgag
     1021 attatttgtg aggaaaatag tttcctacat gtacgaaaga ggtggtcgag ttggtttagg
     1081 tagtcgatgc gtgagttgat aattctcagg gtatggactt ctttttcatg aatgaggtaa
     1141 aagagcaggt attgtttaga gacaatcatt ctgagcatat tttctggata gagggagtat
     1201 ccgattttat gatcaaagtt aataccgccc tctggtgaga agatgagtag gttggtaatt
     1261 taaactatta aacagaattt ttgattaaaa gtattatttt atgagagaaa tcctaatttc
     1321 acaatccata ggcaaactct tgcatttcgt tttttattgg actataatag gttggtataa
     1381 agccttttgt agtaataaaa tgtagaaggt gtagaaagca aggatttaga atatttgtag
     1441 ttaaaaacac aatgttgcta ttccttacga tagggagata gatatggcaa tgatagaagt
     1501 ggaacatctt cagaaaaatt ttgtgaagac tgttaaggaa ccgggcttga agggggcttt
     1561 gcgctccttt attcatcctg aaaagcagac ctttgaagcg gtcaaggatt tgacctttga
     1621 ggttccaaaa gggcagattt taggatttat cggggcaaat ggtgctggga agtcgacaac
     1681 cattaaaatg ctgacaggaa ttttgaaacc aacatctggt ttttgtcgga ttaacggcaa
     1741 gattccccag gacaatcggc aagattatgt caaagatatt ggcgtagtct ttggacaacg
     1801 cacccagcta tggtgggatt tggctctgca agagacctac actgtcttaa aagagattta
     1861 tgatgtgcca aactcgctct ttcataagcg catggacttt ttgaatgaag tcttggattt
     1921 gaaggacttt atcaaggatc ccgtgcggac tctttcactg ggacaacgga tgcgggcgga
     1981 tattgcggcc tccttgctcc acaatcccaa ggttcttttt ttagatgagc cgaccattgg
     2041 tttggacgtt tcggttaagg ataatattcg tcgggcaatt actcagatca atcaagagga
     2101 agaaactacc attcttttga ccactcacga tttgagtgat attgagcaac tttgtgatcg
     2161 gattttcatg attgacaagg ggcaagagat ttttgatgga acggtgagcc aactcaagga
     2221 gacctttggt aagatgaaga ctctctcttt tgaactgcta ccaggtcaaa gtcatctcgt
     2281 ctctcactat gaaggtctgt ctgatatgac cattgataga caaggaaaca gcctcaacat
     2341 tgaatttgat agttctcgct accagtcagc tgacattatc aagcaaaccc tgtctgattt
     2401 tgaaatccgc gatttgaaga tggtggatac ggatattgag gatattatcc gtcgcttcta
     2461 ccgaaaggag ctctaggatg atcaaattgt ggagacgtta taaacccttt atcaatgcag
     2521 gggttcagga gttgattact taccgagtca actttattct ctatcggatt ggcgatgtca
     2581 tgggggcttt tgtggccttt tatctctgga aggctgtctt tgattcttcg caagagtctt
     2641 tgattcaggg cttcagtatg gcggatatca ccctctacat catcatgagt tttgtgacca
     2701 atcttctgac tagatccgat tcgtccttta tgattgggga ggaggtcaag gatggctcca
     2761 ttatcatgcg tttgttgcga ccagtgcatt ttgcggcctc ctatcttttc accgagcttg
     2821 gttccaagtg gttgattttt atcagcgttg gccttccatt tttaagtgtc attgtcttga
     2881 tgaaaatcat atcgggtcaa ggtattgtag aggtgctagg attaactgtc ctttatcttt
     2941 ttagcttaac gctcgcctat ctgattaact ttttctttaa tatttgcttt ggattttcag
     3001 cctttgtgtt taaaaatctt tggggttcca acctacttaa gacttccata gtggctttta
     3061 tgtcggggag tttgattccc ttggcattct ttccaaaggt tgtttcagat attctttcct
     3121 ttttgccttt ttcatccttg atttatactc cagttatgat cattgttgga aaatacgatg
     3181 ccagtcagat tcttcaggca ctccttttgc agttcttctg gctcttagtg atggtgggat
     3241 tgtctcagtt gatttggaaa cgggtccagt cctttatcac cattcaagga ggttagtatg
     3301 aaaaaatatc aacgaatgca tctgattttt atcagacaat acatcaaaca aatcatggaa
     3361 tataaggtgg attttgtggt tggtgtcttg ggagtctttc tggctcaagg cttgaatctc
     3421 ttgtttctca atgtcatctt tcaacatatt ccattcctag aaggctggac ctttcaagag
     3481 atagctttca tttatggatt ttccttgatt cccaagggaa tggaccatct cttttttgac
     3541 aatctctggg cactagggca acgcctagtc cgaaaagggg agtttgacaa gtatttgact
     3601 cgtcccatca atcctctctt tcacatccta gttgaaacct ttcagattga tgccttgggt
     3661 gaactcttag tcggtggtat tttattggga acaacagtga ccagcattgt ttggactctt
     3721 ccaaaattcc tgcttttcct agtttgtatt ccttttgcga ccttgattta tacttctctt
     3781 aaaatcgcaa cagccagtat cgccttttgg actaagcagt caggcgccat gatttacatc
     3841 ttctatatgt tcaatgactt tgctaagtat ccgatttcta tttacaattc tcttcttcgt
     3901 tggttgatta gctttatcgt gcctttcgcc tttacagcct actatccagc tagctatttc
     3961 ttacaggaaa aggatgtgtt ctttaacgta ggaggtttga tgttgatttc tctggttttc
     4021 tttgttattt cccttaaact ttgggataag ggcttagatt cctacgaaag tgcgggttcg
     4081 taaaagctaa agtaagacta aaatcaagaa aggaacttat gatgtttgta attgaagaag
     4141 tcaaggatga aaatcaaaaa aggcagttgt cgctgaggtt ttgaaggatt tgccagaatg
     4201 gtttggaatc ccagaaagca cacaagccta tatagaagga accacgacac tgcaagtttg
     4261 gaccgcctat caggagagtg atttgactgg atttgtaagg ttatcctatt cgagtgaaga
     4321 ttgtgcagag attgattgtc tcggcgtaaa aaagcttatc aaggtagaaa aattgggagc
     4381 caattgcttg ctactttaga gagtgaagct cgtaaaaaag ttggttatct gcaggtcaaa
     4441 acagtggcag aagcttctaa taaagattat gatcgaacaa atgactttta tcgaggtctt
     4501 ggctttaaaa agttagagat tttttctcag ctatggaatc cgcaaaatcc ttgtcagatt
     4561 ttgattaaaa agcttgaata atattacttg acatctattc tcagagtgcc atactgtaag
     4621 tgtaatcgcc gatttagctc agttggtaga gcaaggcact cgtaaagcct aggttatagg
     4681 tagataaacg actgaggagt tgaaaaaata gataggtaga agataaccgt taagccttat
     4741 tcttagcggt tatttatatt atttaatagc gctgatattt catcaattat gcctgttttc
     4801 gtgtttctgg tagttgttca agtttattgc tactattttt gatggtatga atgtgcttat
     4861 aatgtatccc ggttaacgaa agttttggac ttatactctt cgaaaatctc ttcaaaccac
     4921 gtcaacgtcg ccttgccgtg cgtatggtt
//
LOCUS       DAVHLA010000079         4883 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVHLA010000079 DAVHLA010000000
VERSION     DAVHLA010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4883)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4883)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4883
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.079"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(<1..848)
                     /locus_tag="VVO77_002089"
     CDS             complement(<1..848)
                     /locus_tag="VVO77_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU5694025.1"
                     /translation="MKITEYTKKDGTTVYRSSVYLGIDTVTGKKVKTTISGRTKRELK
                     AKALQAQIEFEKDGSTVYKAVEIKTYAELVENWLETYCHTVKKSTLMGTKFKIDKYLL
                     PAFGDYKLDKLTPPVIQKQVNQWAKDYNQLGKGFQEYPLLHSLNKRILKYAVSLQAIP
                     FNPARDVIIPRRKLKEGQKLKYLDDDNLKKFLTYLEQLPNTYKNFFDTVLYKTLLATG
                     LRIRECLALEWSDIDLKNGTLDVNKTLNIIKEITGPKTKSSVRMIDLDNKTVLMLRLY
                     KARQSQ"
     gene            complement(2075..2791)
                     /locus_tag="VVO77_002090"
     CDS             complement(2075..2791)
                     /locus_tag="VVO77_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU5694026.1"
                     /translation="MADNIKRLLSAKGLNPRQLAIALDFKYTTVNDWVNAKTYPRIDK
                     IEMLANFFNVSKSDLVENKNAETPTTSPIQSIYDQLTPPRQEKALTYLKKQLLEQKNE
                     NIVSENIISLDDYRESKTLPVIGVVTAGNGITQDDNLNMEKCFYTDEIPDDYDAIAYV
                     VGNSMEPKIKNGDYLFIKNTPQVDYNTIGIFQVDGANYVKKLRQGYLESLNPECADIQ
                     LDESNDIRTIGEVVSIYREN"
     gene            2994..3185
                     /locus_tag="VVO77_002091"
     CDS             2994..3185
                     /locus_tag="VVO77_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001241280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU5694027.1"
                     /translation="MRLTLKALRANSNMKQSEVAQKLGISTTTWSKWENGKSFPDVAQ
                     VKEIEKLFGVAYDDIIFLS"
     gene            3328..3636
                     /locus_tag="VVO77_002092"
     CDS             3328..3636
                     /locus_tag="VVO77_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001060826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694028.1"
                     /translation="MNNKQVYQAQTTDHGIARALGEEIRMITDVEETTYNGHGEIIVE
                     YTSDVALTKLFDRIKALYEKGESYETKPFLHFKVLEDDIEPSPNGVFTAKEVAEFLGI
                     "
     gene            3658..4284
                     /locus_tag="VVO77_002093"
     CDS             3658..4284
                     /locus_tag="VVO77_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HEU5694029.1"
                     /translation="MELVYMDGKKEPYTLSSIVAECAEVKHRHLKILLNKHREDFESF
                     GKVQFKISPSESGQNVRDYILNEQQATLLITYLRNTEPVRKFKMNLVKAFFEMREELS
                     KFRMQRALEKPKRKTLHDSIENWEQAPKHAHSTMNNLLLKAVTDRNAKQLREERGGYN
                     GIDSLTSDELEQYQAFEDMVIAMIGLNMSYQEIKAMAFRNKKTRQRSA"
     gene            4554..4727
                     /locus_tag="VVO77_002094"
     CDS             4554..4727
                     /locus_tag="VVO77_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000130088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEU5694030.1"
                     /translation="MTDKIKKVGRPKGENSNTVKLTVRVSEQLNSKLEEYGKKNGLTK
                     PETLRKAFENLTK"
BASE COUNT         1498 a          846 c         1006 g         1533 t
ORIGIN      
        1 atttgggatt gtcttgcttt atagagccgt agcatgagta ccgtcttatt atccaagtca
       61 atcattctaa cgcttgattt agtcttaggg ccagtgattt ctttgataat atttaacgtt
      121 ttatttacgt ctagtgtgcc gttttttagg tcaatatcag accactctaa ggctagacac
      181 tcacgaatgc gcaaaccagt agctaaaagc gtcttatata gcaccgtatc aaagaaattt
      241 ttgtaagtgt ttggcagctg ctccaggtaa gtcaagaatt tttttaagtt atcatcatcc
      301 agatatttca gtttttgccc ttctttgagt ttacgccgtg gaataatgac atcacgggca
      361 gggttgaagg ggatagcttg caaagataca gcatatttaa gtatgcgttt gtttagagag
      421 tgaaggagcg gatattcttg gaatcctttg cctaattgat tgtagtcttt tgcccattgg
      481 ttgacttgct tttgaataac tgggggcgtt agcttgtcta gtttgtagtc tccaaaggct
      541 ggaagtagat atttatctat tttgaatttg gtacccatta gggtagattt ttttaccgta
      601 tggcagtatg tttccagcca attctccact agttcggcat aagtttttat ctccaccgcc
      661 ttatatactg tagacccgtc tttttcaaac tctatttgag cctgtagcgc tttggctttg
      721 agttctctct tggttcgccc tgatatagtc gtcttgactt tcttacccgt tacggtatcg
      781 atgccaagat agacgctgga gcgatagact gtagtaccgt cttttttggt gtattctgtt
      841 attttcatgt ttttactcct tttccatcag caggcaagca attagaaaag gttttgagtt
      901 tatactatgc gaggagctac gagaaccccc ttattttcga ttttaagcag taggacggta
      961 aattgttcca gagtagaaaa caaggcggat atggggctta tatggggttg tttgtggtgg
     1021 gtgtttttga tataatgttt tcgccccctc aatttagaga agggaggtgt tatatatgct
     1081 agagttgttt tccctttttc tagctccgtt acttgttaac gtactatctg agcttttcaa
     1141 gctatggata aagagacgta gcaagtagca tttaaccctt taagagggta gcaaaaaacc
     1201 ccatcgctgt aacggtgggg ctttttagtt acatatgcta gaagcactgt ttttcccttt
     1261 atgctttcat tctagcatac aagccccaat atttcaagag ttttattttt ttgatattgt
     1321 ttagagcgct ttaagcgttt ctaaaatgcc aaagtgttga aaattgtcta aattataccg
     1381 cattatactt cattagagag ttatagcctg atgacagggt attgacttac cttttttgtt
     1441 tttctggata atatggtaaa ctagtcatgt aaccgcctga atctttcccg ttatttcagt
     1501 tcaggcgata ttagacaagt cagcagcagc tagcttgtct ttttttgttg tagaaaacta
     1561 gtgtagtaaa aagaaaagtg taccaacata ataagctgat acactgattt ttttgtaaaa
     1621 tataaaagcc cttaactgat agcaggttac ccaataggca acttacgaaa aatacgcaga
     1681 catatcagaa ttacaagcga ctttctaata taactatatc gtttttttat taaaaatcaa
     1741 cttttttgtc gctttttttg tactttttta ttttccaagt aaattccaag taggctaaaa
     1801 acgttgttaa atcaactatt ttttattttc taagtaaatt ccacgcgctt caggattgtt
     1861 ggatattgtg gcgcgtgggt atgctatagg tcgcattttc ggcactttcg gcagccctaa
     1921 aagaaaaata gtagcgatgc gcttcatgtt tgttgcaatt ttgcccaatt ttacgcttta
     1981 gtctgtaaat cggctttcta ttcttcaatt ttccccgttt ttgcacaata gccccatggg
     2041 atggggttgc tattggcgga tatgggggag ttttttaatt ctctctatat atactcacga
     2101 cttcgccgat ggtgcgtata tcgttgcttt cgtctagttg aatatcagca cattcagggt
     2161 taagactttc taaataccct tgacgcagtt tcttgacgta gttagcgccg tctacttgga
     2221 agataccgat agtgttatag tcaacttgag gtgtattctt gataaatagg tagtcgccat
     2281 tctttatctt tggctccata gagttgccga caacataagc gatagcgtcg tagtcgtctg
     2341 gtatttcatc agtataaaag catttttcca tgtttaggtt atcgtcttgg gttatcccgt
     2401 ttccggcggt tacaactccg ataacaggga gcgtcttgct ttctctgtag tcgtccagac
     2461 tgataatgtt ttctgatact atgttttcgt ttttctgctc cagcagctgc tttttaagat
     2521 aagtcaaggc tttttcttgt cttggtggag ttagttggtc atagatggat tggatggggg
     2581 aagtggtagg tgtttctgcg tttttatttt ctactaagtc agactttgaa acgttgaaaa
     2641 aattagccag catttcgatt ttatctatac gtgggtaagt tttagcattt acccaatcgt
     2701 tgacggttgt atacttaaaa tctaatgcaa tagctaattg acgagggttt aaaccttttg
     2761 cacttaaaag tcttttgata ttgtccgcca ttatttgctt atttcctaat gacatggtgc
     2821 aaccgccttt ctataattca taatttaatt atacggttaa aacgtagaaa aagcaaggga
     2881 aacaaaaaaa aagaaaataa aatcaaaaaa agtgttgaca agttatcggt tttaccgtat
     2941 actgtcattg tatccgattt aaacggatat ctaaagaaag gagtgagggc tatttgcgtc
     3001 ttacattgaa agcgttgcgg gctaatagca acatgaaaca atcagaggta gcacaaaaat
     3061 taggaatttc tacaactact tggagtaagt gggaaaatgg aaaaagtttt cctgatgttg
     3121 cccaagtaaa agagattgaa aaacttttcg gtgttgctta tgacgacatt atttttttaa
     3181 gctaatatcc gatttaaacg gatatagaaa ggagcgaccc aatcgcaata ctatattaca
     3241 tctacaagat actccactgg tgctttacca ctggggattg accttctcgg aaaaatatcc
     3301 gacctagaac ataaaggaga aaacaacatg aacaataaac aagtatatca agcacaaaca
     3361 actgaccacg gtatcgctag agcattaggc gaagaaattc gtatgatcac agacgttgaa
     3421 gaaacaactt acaatggaca cggtgaaatc attgttgagt acaccagtga cgttgcattg
     3481 acaaaactat ttgaccgtat taaagcactt tacgaaaaag gcgaaagcta cgaaacaaaa
     3541 ccatttttac attttaaagt attggaagat gatattgaac caagcccaaa tggagttttt
     3601 actgctaaag aggtggcaga gtttttagga atttgattaa caataaggag caaaccaatg
     3661 gaattagtct acatggacgg caagaaagag ccgtatacac tgagcagtat tgtggcagag
     3721 tgtgcagaag ttaagcacag acatttaaag attttgctga ataagcacag agaggacttt
     3781 gagagcttcg gaaaggtgca atttaaaatt tcaccttcag agagtgggca aaatgtacga
     3841 gattatattt tgaacgagca acaagctact ttgttaatca cttacttacg aaatacagaa
     3901 ccagttcgta aattcaaaat gaacctggtc aaagctttct ttgaaatgcg tgaggagctt
     3961 tctaagtttc gtatgcagag ggcgctagaa aagccaaaaa gaaaaacctt gcatgacagt
     4021 attgagaact gggaacaagc acccaagcac gcgcatagca ctatgaacaa cctgctacta
     4081 aaagcagtaa ccgacaggaa cgctaagcag ttaagggaag aacgtggagg ctataatggc
     4141 atcgatagct tgaccagtga cgagctggag caatatcaag cctttgaaga catggtaata
     4201 gccatgattg gcttgaatat gagttatcag gaaatcaagg ctatggcatt cagaaataaa
     4261 aaaacacgcc aaagaagcgc gtgattgcaa caaaaaaggc ttagcaataa ccacaccgca
     4321 aagcctttca cactaagact aaaacgaatt taacaaaaag caggcaagct attattaaag
     4381 aggttttagt aagatttata cctagattat agcataatac agcggtttcc gctagtacat
     4441 tgaaaataaa ataaggtacg ctgggaagat tttaattttt ttcggtttag gggttgacat
     4501 ttaagacgac aagaattata ataatttatg tcgtcaagaa aggaggcaat ccgatgactg
     4561 acaaaataaa gaaagtagga cgtccgaagg gagaaaactc taataccgta aaattaacag
     4621 tcagagttag cgaacagcta aatagtaagc tggaagagta cggtaaaaag aatggtttga
     4681 caaaacctga aaccttgaga aaagcctttg aaaatcttac taaataaaaa ataccttgca
     4741 acttgtcaaa cgccaatccg agaagttgca aagtatccgc ccccacgaat gaggtacgta
     4801 aatatcttat catgcgtact cttatttgtc aaacatagaa atagagtgcg ctttttgcgt
     4861 acccaaaaat gaggtaaaga atg
//
LOCUS       DAVHLA010000080         4846 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVHLA010000080 DAVHLA010000000
VERSION     DAVHLA010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4846)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4846)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4846
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.080"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(<1..848)
                     /locus_tag="VVO77_002095"
     CDS             complement(<1..848)
                     /locus_tag="VVO77_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEU5694031.1"
                     /translation="MKITEYTKKDGSTVYRSSVYLGIDTVTGKKVKTTISGRTKRELK
                     AKALQAQIDFEKDGSTVYKAVEIKTYAELVENWLETYCHTVKKSTLMGTKFKIDKYLL
                     PAFGNYRLDKLTPPIIQKQVNQWAKDYNQLGKGFQEYPLLHSLNKRILKYAVSLQAIP
                     FNPARDVIVPRRKEKEGQKLKYLDDDNLKKFLTYLEQLPNTYKNFYDTVLYKTLLATG
                     LRIRECLALKWSDIDLKNGTLDVNKTLNIIKEITGPKTKSSIRVIDLDNKTVLMLRLY
                     KARQSQ"
     gene            complement(1597..2220)
                     /locus_tag="VVO77_002096"
     CDS             complement(1597..2220)
                     /locus_tag="VVO77_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001080850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU5694032.1"
                     /translation="MNRLKELRQKNELSQKEIAEILGFSLRSFQRMENGESQIKPEKA
                     QQLADFFGVSVGYLLGYIDDSEIYDDEVVIEPEEGIVLAYSNKRSNKKLQEKMFKDFI
                     TFFRDNTIFVSDEEILSLYSMVQAANLNNSTPRGTHFNNLLFSNTDEAKQIIKSYSFV
                     FGNEFARNDLDEQIHGYISEETRTKEKTEKLLKVLQSAYGERDYLDY"
     gene            2439..2639
                     /locus_tag="VVO77_002097"
     CDS             2439..2639
                     /locus_tag="VVO77_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEU5694033.1"
                     /translation="MSKLRGYRVMLGLTQQQMADKLKISLQSYNNKELGKTPFNDKER
                     LAIKSMVAEIKSDITIDELFYS"
     gene            2655..3425
                     /locus_tag="VVO77_002098"
     CDS             2655..3425
                     /locus_tag="VVO77_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694034.1"
                     /translation="MKRNYTRVIDEMRTTHGLNLVAIGQRIGIDPRTVGKWAQGKHKP
                     NKESRKRLNKLYREVKQDMTTQQKGLCDFFGNFYPKGEQHNKKEVLEVVTTQRFGSKY
                     FDVYGDIQNPLFVAVEVAEMIEIQNTTDLLKRVDDDEKLTYVISRAGQKREMNMLTEF
                     GVYEVLSQSRKPLAKEFKKVVKHILKEIRLNGYYMAGELVEEPQTTIKAPGTLAEVER
                     YYIDTLAKAIAEAQNMDEKSRLTSKLTRFMQEVEPQWN"
     gene            3416..4018
                     /locus_tag="VVO77_002099"
     CDS             3416..4018
                     /locus_tag="VVO77_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HEU5694035.1"
                     /translation="MELVYMDGKKEPYTLSSIVAECAEIKHRHLKILLNKHREDFESF
                     GKVQFKISPSESGQNVRDYILNEQQATLLITYLRNTEPVKEFKKDLVKAFFEMRDELS
                     KRYLQRELEKPKRKTLTEAIKSWEKAPQHAYSTLTNLLLKGATGKNKAQLMQERESEN
                     GIDSLTSAELTNYQRLEDMAIAMMNLNMRYSEIKELIFKV"
     gene            4030..4278
                     /locus_tag="VVO77_002100"
     CDS             4030..4278
                     /locus_tag="VVO77_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694036.1"
                     /translation="MENEFKTVTNAKGVEIPKYFKDFKKLVEMDRQLAEYLCMNYELL
                     DSEDLGAFLETVEQGFSWILELIESKDLLYSPQTGKKA"
     gene            4518..4688
                     /locus_tag="VVO77_002101"
     CDS             4518..4688
                     /locus_tag="VVO77_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694037.1"
                     /translation="MGKTLGRPKSDNPKNKQLKIKMTEQDFNNLEELAKKKNMTKTDI
                     VMRGIELVKSEP"
BASE COUNT         1581 a          849 c         1011 g         1405 t
ORIGIN      
        1 atttgggatt gtcttgcttt atagagccgt agcatgagca ccgtcttatt atccaagtca
       61 attaccctaa tacttgattt agtcttaggg ccagtgattt ctttgataat atttaacgtt
      121 ttatttacgt ctagtgtgcc gttttttagg tcaatatcag accatttgag ggctaaacac
      181 tcacgaatac gcaaaccagt cgctaaaagc gtcttatata gcaccgtatc gtagaaattt
      241 ttgtaagtgt ttggcagctg ctccaggtaa gtcaagaatt tttttaagtt atcatcatcc
      301 agatatttca gtttttgccc ttctttttcc ttacgacgtg gcacgataac atcacgggca
      361 gggttaaagg ggatagcttg caaagatacg gcatatttaa gtatgcgttt gtttagagag
      421 tgaaggagcg gatattcttg gaatcctttg cctagttgat tatagtcttt tgcccattga
      481 ttgacttgct tttgaatgat tgggggcgtc agtttatcca gcctataatt tccgaaagct
      541 ggaagtagat atttatctat tttgaatttg gtacccatta aggtcgattt tttaaccgta
      601 tggcagtacg tttctagcca attctccacc agttcggcgt aagtctttat ctcaactgct
      661 ttatatactg tagacccgtc tttttcaaag tcgatttgag cctgtagcgc tttggctttg
      721 agttctctct tggttcgccc tgatatagtc gtcttgactt tcttacctgt tacggtatcg
      781 ataccaaggt agacgctaga gcgatagact gtagaaccgt cttttttggt gtattctgtt
      841 attttcatgg ttttactcct ttttccatca gcaggcaagc aattagaaaa ggttttgagt
      901 ttataccatg cgagggactg cgagaatgcc cctattttcg attttaatta gccaggcggt
      961 aaataatacc agaataggaa ataaggcgga tatggggttt gtatgggcgt ttttacatat
     1021 catcaaagag tgaaagttgg ttattatccg gttgcttttt aagtttcttt tgtttgtttt
     1081 ttaggtcttg gcaaccacgc ttttttcgga gtcttcacat aaatgttgga aaaagtcgga
     1141 ttttcaagaa tactggaaaa aaacaatttt cttcattttc tgagtcccta aaaagcgatg
     1201 gggtaaacaa ttccaatccc gtttctatta gttcttaatg gttggaaaac taacatttct
     1261 aacaccctaa aaaggagaag ggtttagaca aggtcagagg acttgctgaa gcccgagaaa
     1321 gcacgcgctt caggattgtt gaacattgtg gcgcgtggta ggctataggt cgcattttcg
     1381 gaactttcgg cagccctaaa agaaaaatag tagcaatgcg cttcatgttt gttgcacttt
     1441 tgcccaattt tgcgctttag tctgtaaatc ggctttctat tcttcaattt tccccgtttt
     1501 tgcacaatag acccatggga tggggttgct attggcgaat atgggggagt tttttaattc
     1561 tctctatata tactcacgac ttcgccgata gtaaatttaa tagtccaggt agtcgcgttc
     1621 tccatatgct gattgcaaaa cttttaagag tttttcggtt ttttcttttg ttctggtttc
     1681 ttcagagata tacccgtgaa tttgctcatc taaatcattt ctagcaaact cgttaccgaa
     1741 aacaaatgag taagatttga ttatttgttt ggcttcgtcg gtattagaaa aaagtaaatt
     1801 attaaaatgt gtacctcttg gtgtggaatt attaagattg gcagcctgca ccatagagta
     1861 cagagataaa atttcttcat cactgacaaa gatagtgtta tcacggaaaa atgtaatgaa
     1921 gtctttaaac atcttttcct ggagcttttt gttagaacgt ttattagaat atgctaaaac
     1981 aattccttct tcaggttcta ttacaacttc atcgtcatat atttcagaat catcaatata
     2041 ccccaacaga tatccaacgc ttaccccgaa gaagtcagct agttgctggg ctttttctgg
     2101 tttgatttgg ctttctccgt tttccattcg ttggaatgac cttaaagaaa atcctaaaat
     2161 ttcagctatt tctttttgag atagctcgtt tttttgtctt aattctttca atctattcat
     2221 gctttatcac acctttcaca gatgattata accctatgtt taaaaaaagt caaaaaatga
     2281 cgtaaaaaaa tcaaaaaaac tattgacaac gtctaaaact gacgttataa taaaattcaa
     2341 gcttaggaga cgtcataaaa cgacgcctag cgacccctcc aacctttcac actttcaatc
     2401 tattcatgga gggggatttt ttagaaaggg ggaaagctat gagtaaacta cgaggctatc
     2461 gggttatgtt aggactaact cagcaacaaa tggcggacaa gctaaaaatt tctttgcagt
     2521 cgtacaacaa caaagaatta ggtaaaacgc cattcaatga taaagaacgt ctagcgatta
     2581 agtcaatggt tgcagaaatc aaatcagata taaccataga tgaactattt tatagctaga
     2641 aaggcaggca agcaatgaag aggaactata caagggtcat cgatgaaatg cgaaccactc
     2701 acgggctgaa cttggtagct attggccaac gaataggcat agatccccga acagttggca
     2761 agtgggcaca gggcaaacat aagcccaaca aggaaagcag aaaaagacta aacaagttat
     2821 acagagaggt gaagcaagac atgacaacac aacaaaaagg tttatgtgat ttttttggga
     2881 acttctatcc aaaaggagaa caacacaaca aaaaggaagt tttggaagtt gtaacaactc
     2941 aacgattcgg atctaaatat tttgatgttt atggagacat tcaaaatccg ttatttgtag
     3001 cggtagaggt tgctgagatg attgaaatcc aaaacaccac agatttacta aaacgggtag
     3061 atgatgatga aaagctgacc tatgtaatat ctagggcagg tcaaaaaaga gaaatgaata
     3121 tgctgacaga gttcggagtc tatgaagttt tatcgcagtc acgcaaacca ctagcaaaag
     3181 agtttaaaaa agttgttaag cacattctga aagaaatccg actaaatggc tactacatgg
     3241 ctggggaatt ggtggaagaa ccacagacca ctataaaagc ccctggcacg ttggcagagg
     3301 tagagcggta ttatatcgat acactagcca aagccattgc agaggctcag aatatggacg
     3361 agaagagccg tctgacaagc aagctaacca gattcatgca ggaggtagaa ccacaatgga
     3421 actagtctat atggacggca agaaagagcc gtacacatta agcagtattg ttgcagaatg
     3481 tgcagaaatc aagcacagac atttaaagat tttgctgaat aagcacagag aggactttga
     3541 gagcttcgga aaggtgcaat ttaaaatttc accttcagag agtgggcaaa atgtacgaga
     3601 ttatattttg aacgagcaac aagctacttt gttaatcact tacttacgaa atacagaacc
     3661 cgtaaaagag tttaagaagg acctggttaa agcctttttt gaaatgcgtg atgaactttc
     3721 taaacgctat cttcaacggg aactggaaaa gccaaagcgc aagaccttaa ccgaagctat
     3781 caaatcatgg gagaaagcac ctcagcatgc ctatagcact cttacaaacc tactgctaaa
     3841 gggagcgact gggaaaaaca aagcccaact catgcaagag cgagaaagtg aaaacggtat
     3901 tgacagttta acaagtgcgg aactgacaaa ctatcaacgc ttggaagata tggcaatagc
     3961 gatgatgaac ttgaatatga gatattcaga aattaaagaa ctaattttta aagtatagga
     4021 gtatagaaaa tggaaaatga atttaagaca gttacaaatg ccaagggagt agaaattcct
     4081 aagtatttca aggattttaa aaagctagtt gagatggaca gacaactagc cgaatatctt
     4141 tgtatgaact acgagttatt ggacagtgaa gacctaggtg catttcttga aacggtggag
     4201 cagggattca gctggattct ggaacttatc gaaagtaaag atttgcttta tagcccccag
     4261 acagggaaga aagcatgaaa aagacaataa aaaaagtcac ttgctgaacg tttggcgact
     4321 gaagcaagcg actggatcaa gggtatagat atttttctat acctagatta tagcataata
     4381 cagcggtttc cgctagtaca ttgaaaataa aataaggtac gctgggaaga ttttaaattt
     4441 ttttcggttt aggggttgac ttaaagggta caccgttata taataaaagg gtaccccgaa
     4501 agaaagagag gtcaaaaatg gggaaaacat taggacgacc taaaagcgat aacccaaaaa
     4561 acaagcaact aaaaattaaa atgactgaac aggattttaa taatttagaa gaacttgcca
     4621 aaaagaaaaa catgactaaa acagatatag tcatgcgagg gattgagctt gtaaagtctg
     4681 aaccataacg aaaccgccta ccgtgtcact tgtttggcga cagaacacga tagacggcga
     4741 tgcaccacaa atgaggtacg taaatatctt atcatgcgta ctcttatttg tcaaacatag
     4801 aaatagagtg cgctttttgc gtacccaaaa aatgaggtat acaatg
//
LOCUS       DAVHLA010000081         4808 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVHLA010000081 DAVHLA010000000
VERSION     DAVHLA010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4808)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4808)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4808
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.081"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(8..250)
                     /locus_tag="VVO77_002102"
     CDS             complement(8..250)
                     /locus_tag="VVO77_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694038.1"
                     /translation="MKILNIKLANVEQTDSGFEHWVDVTYNVPILKNEYTVRLLLLFG
                     FEIEDPEVIEYLVNAWKYRELVLHSVRMYDMEREAS"
     gene            complement(482..1438)
                     /gene="lytA"
                     /locus_tag="VVO77_002103"
     CDS             complement(482..1438)
                     /gene="lytA"
                     /locus_tag="VVO77_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEU5694039.1"
                     /translation="MDIDTSRLRTGLPQVGVQPYRQVHAHSTGNRNSTAQNEADYHYR
                     KDPELGFFSHVVGNGRVMQVGPVNNGSWDVGGGWNTESYAAVELIESHSTKVEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLASWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLAD
                     RWKKYTDGNWYWFDNSGEMATGWKKIAEKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPDFTVEPDGLITVK"
     gene            complement(1444..1773)
                     /locus_tag="VVO77_002104"
     CDS             complement(1444..1773)
                     /locus_tag="VVO77_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEU5694040.1"
                     /translation="MQQITEIITNGAISILVILAGIAVKAVKDYLVQKGGEKTIKIVE
                     ILAKNAVNAVEQVAAETGYKGDEKLAQARAKVRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKG"
     gene            complement(1777..2076)
                     /locus_tag="VVO77_002105"
     CDS             complement(1777..2076)
                     /locus_tag="VVO77_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004246694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694041.1"
                     /translation="MPIEEAEKIAQSQVAWAILFILLFFIIIRYLIKTSDKREKKIMD
                     LHEQSKADSNRREERLMTHLEKTTTELTTITHTVGDIQKEMVRMNDRMEEIEKGE"
     gene            complement(2085..2435)
                     /locus_tag="VVO77_002106"
     CDS             complement(2085..2435)
                     /locus_tag="VVO77_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694042.1"
                     /translation="MAETIQNTDNLLDLTKITEPFDLASALRYMKENGEFIRCKNVSD
                     DFYMYRDVQKRPVIVNGRRQFKDVETVWAFNQWGGTIATINVAVLLNHEFYIMKFDAE
                     GNPDWTVPTVEPKE"
     gene            complement(2438..2641)
                     /locus_tag="VVO77_002107"
     CDS             complement(2438..2641)
                     /locus_tag="VVO77_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694043.1"
                     /translation="MNTEQLNQALQMTIREMSTTSTDSMITSNILSIQLNEQREENQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            complement(2622..4543)
                     /locus_tag="VVO77_002108"
                     /pseudo
     CDS             complement(2622..4543)
                     /locus_tag="VVO77_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841354.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
BASE COUNT         1224 a         1111 c          872 g         1601 t
ORIGIN      
        1 cagtatttta acttgcttct ctctccatat catacatcct cacagaatgt aagaccagct
       61 cacgatattt ccaagcgttg accaggtatt caatcacttc aggatcttca atttcaaaac
      121 caaagagcag caacaatcta accgtgtatt cgtttttcaa aattgggacg ttgtaagtca
      181 catccaccca atgctcaaag cctgaatctg tctgctctac atttgctagt ttaatattta
      241 aaatcttcat ttttattcct cctacttatc tattcgtaaa agaagataaa aagttatgaa
      301 aaaatcatta cttttttaat tcagacagta ctttcagagc aattttgtta atgtcaacaa
      361 aattggcaac caagcgattt aatactattt gttgacgcca acaagtcaat tttcagacaa
      421 acaaaaaaac cgcaagcctg agcctgcggt gaaagaacaa tttagaaagt ttcctttcta
      481 tttatttaac tgtaatcaag ccatctggct ctactgtgaa gtctggctta tctgccagtg
      541 ttccgtctgg tttgaggtag taccagcctg ttccgtctgc ggactggata aaggcatttg
      601 ataccatagc gccttcttta gcgtctaagt agtaccaagt gtccttgtac ttgacccagc
      661 ctgtcttcat ggcaccttct tcgttgaaat agtaccactt ctcagcaatt ttcttccagc
      721 ctgtagccat ttcgcctgag ttgtcaaacc agtaccagtt gccgtctgtg tacttcttcc
      781 agcggtctgc aagcatatag cctgagccat cgaaataata ccaggtaccg ttgattttct
      841 caaacttatc ttttggataa gagccgtctg aatgtacgta ccagtagcca gtgtcattct
      901 tctgccagcc tgtttcaatc gtcaagccgt tctcaatatc atgcttaaac tgctcacggc
      961 taatgcccca acttgcaaga tatggatatg gatccacatg gtctgagtgg ttgtttggtt
     1021 ggttattcgt gcaatactcg tgcgttttaa ttccagctaa actccctgta tcaagcgttt
     1081 tcggcaaacc tgcttcatct gctagattgc gtaagagttc gatataaagg cggtagtccg
     1141 tcatgaactc tactttagtt gaatggcttt caatcagttc aaccgctgcg taactctcag
     1201 tattccaacc gcccccaaca tcccaacttc cgttgttcac aggacctact tgcatgacac
     1261 ggccgtttcc gacaacatgt gaaaagaacc ctagttcagg gtcctttcta tagtggtaat
     1321 cagcctcatt ttgagctgtt gagttacggt tgcctgttga gtgggcgtgt acttgtcgat
     1381 aaggctgcac accgacctga ggcaagcctg tacgtagtct gcttgtatcg atatccatta
     1441 ctcttatcct ttccaagcgt cgttcatctg tttcactgcg gactctacga aggtgtctaa
     1501 gtctttgtca gtcatgctaa tattgtattt tgtaagctca gcacggactt tagcgcgagc
     1561 ctgtgccagt ttttcatctc ccttgtagcc agtttcagca gctacttgct caacggcatt
     1621 aactgcgttc ttagccaaga tttcaacaat cttgatagtc ttttctccac ctttttgaac
     1681 caggtagtcc ttgactgcct tgactgcgat accagccaaa ataacaagga tgctgattgc
     1741 tccattagta atgatttcag taatttgttg catttgttat tctccttttt cgatttcttc
     1801 catgcggtcg ttcatgcgaa ccatttcttt ttgaatgtct ccgaccgtgt gagtgattgt
     1861 ggttaattct gtagtggtct tttctaggtg agtcatcaaa cgctcttctc gtctattaga
     1921 gtcggccttt gattgctcgt gcaaatccat aatcttcttc tctcgcttgt ccgaagtctt
     1981 gataagatat cgaatgataa taaaaaaaag caagataaac aaaatcgccc aagctacctg
     2041 actttgagcg attttttcag cttcttcaat tggcatacaa cctcctattc tttaggttct
     2101 accgttggaa ccgtccagtc aggattgccc tctgcatcaa atttcatgat atagaattca
     2161 tgattcaaca gaacggctac gttgattgtt gcgattgtac caccccactg attgaacgcc
     2221 caaacggttt caacatcctt gaattggcga cggccattta caatcacagg acgtttttga
     2281 acgtcacgat acatatagaa gtcatcgctt acattcttgc aacgaatgaa ctctccattt
     2341 tctttcatgt agcgcaaagc gctcgcaaga tcaaatggtt ctgtgatttt tgtaaggtct
     2401 agtaagttat ctgtgttttg aattgtttct gccatgtcta ttctcctttg tctgctggtt
     2461 tagtttgttc atcaagcaga gcttccagct catccactcg tgcttgaagt ctttgattct
     2521 cttccctttg ctcattcaac tgaatactca agatattact tgtaatcatc gaatctgttg
     2581 aagttgttga catttcacga attgtcattt gtaaggcttg gttaagctgt tctgtgttca
     2641 ttttctaagt tctccaatct gtgtgttcgt tttctatttt caagagcaag ctcctgaatt
     2701 gctttaagtg cgatattggt caacatgttg ttattcatgc tattgttttc tccatttttt
     2761 ctattttttg atttaattct tgaatagcct tgattaagta aggaactaaa gcggtatagt
     2821 cgatatgcag atagccatct ggattctcag gatctcgtga gacaattttt ggaacgatgg
     2881 tttcagcctc ttgagctatt agaccaatct cctcatgttt cttattttcg atgaaatcaa
     2941 atgcaaccat tcttaatctg ttgattttgt ccaaggcttt cacagctgta tctgtgatgt
     3001 tctcttttaa gcgtctgtct gatttttgtt ccatccaata cttcacgcta ccgctaccga
     3061 cctgattcca ccaaacaacc gcattccttc cgcctttggg attccaacca tcaccaagca
     3121 catctttact tccaagttcg ataccatttg aaaacacagg agaacgagaa aaagtagtat
     3181 tcccatagaa gtttgctctc gatgaattcg aaaaatccac ttgatcataa aaaccgactt
     3241 cattcctaca gtacattttc ccatcagtat tgacgttcca tgctttaggt ccggcatagt
     3301 tccaattatt tccccagttc gcccagaagg ctgtccggac tccatacccg gcaccattcc
     3361 ccataccaac agagaactga ttgacacctg aaatccagcg accgccaccc tggtcaaatt
     3421 gaccaagtgt gaatccaccg attcggcctt gataggcttc taggaaggtt gagctagaaa
     3481 tgacggactc aaccttaata gagaagatac gtttagatat cagttggtca ataaaagcat
     3541 catttgcagt taattttcta ataagcgcat tgtcaacttt caacttctca gcagttaccg
     3601 cttcagcatc taatatcgta gtcgtgaccg aaccagcttc aaaattgccc gttttgagct
     3661 tatcaaccat ggcagacttg atgactgctc tgtcaatcag ggtctctcca gtgatgtggg
     3721 tcaatttccc aacaaagcgg ttatgtccat tggcgccaag attgattcca gagatgatat
     3781 ctccagccga gttgatgttt tgaactgccc atgagccagt tagttgactt tgaacagagc
     3841 gaatcgcttc gtccgtgtct tcaggagctt cggtgtacgg tgttgcatac gatccttttt
     3901 caagtttaag acctgcaata tatagatttg tattttgatt aagtcgttct acacgaggaa
     3961 agatgaagcc gtccacagta attttgaagg taaatgagta acgtttccat tcacttgtta
     4021 tagcgaccga tgtttcagat ggaacacccc aacctttctc aacagatcca tttctattta
     4081 catagaaatt tactgtatca ttcttccagt cgctcttcat ccataagctg aatgtataga
     4141 cttcaccaat ttttgcatca atctcttgtc caacgccatt ccacgaatta tttttaaata
     4201 ggacatcaac acctttgtat ttttcagcgt gctttttcca atttgcaccc ttgtttttcc
     4261 aaccccctga gaagtctttt gtgcctttca acaaattttg accattgctg gcatttttag
     4321 ccacctcaac ctgaaacagt tgattagtca gagccatgcg agcaacctta tccgcaattc
     4381 cattttcagt attgcccaaa attcgctcgt aaagtttact ggtttcctta acacgctgga
     4441 agtcagtagt ctctactttt cgcgctagtt gattggtcac attcgcaaat tgactatcag
     4501 cattcgcttt gtttgcagaa acctgatcag atattctacc catttgtcgt tcagcattat
     4561 ccttgtttgt agcgacctga gtctttaaat ttgaaatctg attatctgtg ccttgtttat
     4621 tactgtttat ccgatttgaa atatttgaaa tctgagtagt ggttccttgc tcactgcttg
     4681 taagtctatt tgaaaggcca ctgatttgac cgcccacatc ttgcttataa gtagttatct
     4741 gacttgaaat atccgtgaac ttaccatcta cagattgacg atagctagcg atttgactag
     4801 cgatgtct
//
LOCUS       DAVHLA010000082         4637 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVHLA010000082 DAVHLA010000000
VERSION     DAVHLA010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4637
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.082"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            <1..>4637
                     /locus_tag="VVO77_002109"
     CDS             <1..>4637
                     /locus_tag="VVO77_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU5694044.1"
                     /translation="EVQPALPEAVVTEKGEPEVHEKPDYTQPIGANLVEPEVHEKLAY
                     TEPVGTTGVDENGNLIEPPVNDIPEYTEPISTVSEVASEREELPSLHTDIRTETIPKT
                     TIEESDPSKFIGDNSVKQVGEDGERQIVTSYEELHGKKISESVETVTILKEMKPEIIV
                     KGTKERPKEKTAPVLTLTKVTEDAMNRSANLNYELDNKDNAEISSIVAEIKDGDTVVK
                     RVDLSKEKLTDAVQNLDLFKDYKIATTMIYDRGQGSETSKLDERPLRLELKKVEIKNI
                     ASTNLVKVNDDGTETPSDFMNEKPSEEDVKKMYLKITSRDNKVTRLTVDSIEEVTEEG
                     QKLYKITAEAQDLIQHTDPTKVRNKYVYYIEKPHPKEDNVYYNFKDLVDAMNTDKNGT
                     FKLGADLNATGVPTPKKWYVDGDFRGTLKSVEGKHYTIHNTERPLFQNIIGGTVTKVN
                     LGNVNINMPWADRIAPIADTIKGGAKIEDVKVTGNVLGRNWVSGFIDKIDNQGTLRNV
                     AFIGNVTSVGDGGQFLTGIVGENWKGLVERAYVDANLIGKKAKAAGIAYWTQNSGDNH
                     KVGVEGAVKKGIVKGTIQVESPVEVGGAVGRLSHHGYIGEVVSMMKVKKGEIFYGSSD
                     MNDDPYWVANNVRGNYVVNGVSEGTISYARAKEHHRIKPISQSEADTKIMMLGITAQD
                     FAINEPVVNRLNRLTRKEDEYKSTQDYKVDRDLAYRNIEKLQPFYNKEWIVNQGNKLA
                     EDSNLAKKEVLSVTGMKDGQFVTDLSDIDKIMVHYADGTKEEMDVTKNADSKVKQVRE
                     YTIAGQNVVYTPNMVEKDRNQLIQDIKDKLASVQLISPEVRALMDARKKPEENTDERK
                     NGYIKDLYLEESFAETKANLDKLVKSLVENADHQLNSDEAAMKALVKKVDENKAKIMM
                     ALTYLNRYYDIKYGDMTIKNLMMFKPDFYGKSVDLLDFLIRIGSSERNIKGDRTLDAY
                     RDMIGGTIGKSELHGFLDYNMRLFTNDTDLNDWFIHAAKNVYVSEPQTTNPDFVNKRH
                     RAFDGLNNGVHNRMILPLLTLKNAHMFLISTYNTMAYSSFEKYGKYTEEARNEFKKEI
                     DKVAHAQQTYLDFWSRLALPSVRDQLLKSENRVPTPVWDNQNYSGIKGINRMGYDEKK
                     VPIAPIRELYGPTWKFHNTNWNMGAMASIFPNPNNNDQVYFMGTNMISPFGISAFTHE
                     TTHVNDRMLYFGGHRHRQGTDVEAYAQGMLQTPSSIGHQGEYGALGLNMAYHRENDGD
                     QWYNYDPDKLQTREDIDRYMKNYNEALMMLDHVEADAVLPQLNGDNSKWFKKIDREMR
                     RNLGDGLNNLVAPHQWDNVRDLNQEESSKKLSSINDLIDNNFMTKHGNPGNGRYRPED
                     FRPNSAYVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGYYGYDKGFTSYVSSKYQG
                     EADKQNQGRLGDDFIIKKVSNNQFSNLEDWKKYWYHDVKSRAEKGFTEITIDGQTIHN
                     YNELKDLFDKAVTEDLKKAGNYSNTENLKSKVFKALLKNTDGFFNPLFKKD"
BASE COUNT         1657 a          725 c          966 g         1289 t
ORIGIN      
        1 gaagtacaac cagccttacc cgaagcagtt gtaactgaaa aaggcgaacc agaagttcat
       61 gagaagcctg actatacgca accaataggt gcaaaccttg ttgagcctga agttcatgag
      121 aaactagcat acactgaacc tgtaggtaca acaggagtag atgaaaatgg aaacttgatt
      181 gagccacctg ttaacgatat tccagagtat actgaaccaa tatctacagt ttcagaagtt
      241 gcatcagaaa gagaagagtt gccttcttta cataccgata ttcgtacaga gactattcct
      301 aaaaccacta tagaagaatc tgatcctagc aaatttatag gcgataattc tgttaaacaa
      361 gttggtgagg atggcgaacg tcaaattgtt actagctatg aagagttaca tggcaaaaaa
      421 atcagcgagt cagttgaaac agtaacaatt ttgaaagaaa tgaagcctga aattattgta
      481 aaaggtacaa aagaaagacc aaaagaaaaa acggctcctg ttttaacctt gaccaaagta
      541 acagaagatg ctatgaatcg ttctgccaac ttaaattatg agcttgataa taaagataat
      601 gctgaaatat caagtattgt agctgaaatt aaagatggtg atacagtagt taaaagggtt
      661 gatttatcta aagaaaaatt aactgacgct gtacaaaatt tggatttgtt taaagattat
      721 aagattgcaa caacaatgat ttatgatcgt ggtcaaggtt ctgaaacgtc taaactggat
      781 gaaagacctc tgcgtttgga gttgaaaaag gtcgaaatta aaaatatcgc atctactaat
      841 ttagtgaagg taaatgatga tggtactgaa acacctagtg attttatgaa tgaaaaacct
      901 tcagaagaag atgttaaaaa aatgtactta aaaatcacta gtcgcgataa taaggtaact
      961 cgtttaactg tagactctat tgaagaagtg actgaagaag gtcaaaaact ttacaaaata
     1021 actgctgaag cacaagattt gattcaacac acagacccaa cgaaggttcg taataagtat
     1081 gtttattata tagaaaaacc ccatcctaaa gaagataatg tctactataa ctttaaagat
     1141 ttagtagatg ctatgaatac tgataaaaat ggtacattta aacttggtgc agatttgaat
     1201 gccactggtg ttccaacacc taagaaatgg tatgttgacg gcgactttag aggtacattg
     1261 aagagtgtag aggggaaaca ttatactatc cacaacacgg agcgtccgtt attccagaat
     1321 attattggtg gtacagtaac caaagtaaat ctgggaaatg taaatatcaa tatgccatgg
     1381 gcagaccgca tcgcaccgat tgctgacact attaaaggtg gcgctaaaat tgaagatgtc
     1441 aaagtgactg gtaacgtatt aggtagaaac tgggtatctg gatttattga taagattgac
     1501 aaccaaggta cactcagaaa tgtagccttt atcggaaatg tgacatctgt aggtgatggt
     1561 ggtcaattct tgaccggtat cgttggtgag aactggaaag gactagtcga acgtgcgtat
     1621 gttgacgcaa atcttattgg caagaaagcc aaggctgctg gtattgctta ttggacacaa
     1681 aacagtggtg acaatcataa agttggtgtc gaaggtgcag tcaagaaagg aattgtgaag
     1741 ggtaccattc aggtagaaag tcctgttgaa gtcggcggtg ctgttggacg tttgagtcat
     1801 catggttata tcggggaagt cgtatctatg atgaaagtta agaagggtga aattttttat
     1861 ggttctagtg atatgaatga tgacccatat tgggtggcga ataatgtacg aggaaattat
     1921 gtagttaatg gtgtgagtga aggtacgata tcttatgctc gtgctaaaga acaccatcgt
     1981 atcaaaccaa tttcacagtc agaagcagat actaaaatta tgatgttagg tattacagca
     2041 caagattttg ctatcaacga acctgtggtc aatcgcttaa accgtttaac cagaaaagaa
     2101 gatgaatata agtcaaccca agactataaa gtagatcgag atctggctta tcgtaatatt
     2161 gagaaacttc aaccatttta taacaaagaa tggattgtca accaaggtaa caaacttgca
     2221 gaagattcaa acttagctaa gaaagaagtc ctttctgtta cgggtatgaa ggatggacag
     2281 tttgtaactg acttatcaga tattgataag attatggttc actatgctga tggtactaaa
     2341 gaagaaatgg acgtcactaa gaatgctgat tctaaagtga aacaagttcg tgaatatacc
     2401 atcgctggac aaaacgttgt ttatacacca aatatggttg agaaagaccg taaccaattg
     2461 attcaagata tcaaagataa gttggcgtca gttcaattga tttctcctga agtacgtgct
     2521 ttgatggatg cacgtaagaa accagaagaa aatactgatg aacgtaagaa tggttatatt
     2581 aaagaccttt acttagaaga aagctttgct gaaacgaaag ctaatcttga taaattggtt
     2641 aaatccttag ttgaaaatgc agatcatcaa ttaaatagtg acgaagcggc tatgaaagca
     2701 cttgttaaga aggtggatga aaataaagct aaaatcatga tggctctgac ttatctcaat
     2761 cgttactatg atatcaagta tggggatatg actatcaaga acttgatgat gtttaaacct
     2821 gatttctatg gtaaatcagt tgaccttctt gatttcttga ttcgaattgg atcaagtgag
     2881 agaaatatca aaggtgacag aactttggat gcttatcgtg atatgattgg tggaactatt
     2941 ggtaagtctg aattacatgg attcttagat tacaatatgc gtctcttcac taacgatact
     3001 gatttaaatg attggttcat ccatgcagct aagaatgtat atgtatcaga acctcaaaca
     3061 acgaacccag attttgttaa taaacgacat cgtgcatttg atggtttgaa caacggtgtt
     3121 cataatcgta tgattctacc tctattaact cttaagaatg cacatatgtt cttgatttca
     3181 acttacaata caatggctta tagttctttt gagaaatatg gtaagtatac agaagaagct
     3241 agaaatgaat tcaaaaaaga aattgataag gttgcacatg ctcaacaaac atacttagac
     3301 ttctggtcac gtttagcatt gccaagcgta cgtgaccaat tactcaagag tgagaatagg
     3361 gtaccaactc ctgtgtggga taaccaaaac tatagtggta ttaaaggaat aaaccgtatg
     3421 ggttatgatg agaagaaagt accaattgcg ccaattcgtg agttatatgg tccaacttgg
     3481 aaattccata ataccaactg gaatatggga gctatggcat ctattttccc aaatcctaat
     3541 aacaatgacc aagtttattt catgggaaca aatatgatta gtccgtttgg tatttcagcc
     3601 tttactcatg aaactacaca cgttaatgat agaatgcttt acttcggtgg tcatagacac
     3661 cgtcaaggta cagacgtcga agcctatgct caaggtatgc tacaaactcc gtcaagtatt
     3721 ggtcaccaag gtgaatatgg tgctttaggt ttgaacatgg cttatcatcg tgaaaatgat
     3781 ggtgaccaat ggtataacta tgaccctgat aagcttcaaa ctcgtgaaga tatcgatcga
     3841 tatatgaaaa actataatga agcactgatg atgctagatc atgtagaagc agacgccgta
     3901 cttccacaat tgaatggtga taatagcaag tggttcaaga aaattgatag agaaatgcgc
     3961 agaaatcttg gggatggttt gaataactta gtagcaccgc accaatggga caacgttcgt
     4021 gacttaaatc aagaagagag ttctaagaaa ttatcaagta ttaacgattt gattgataat
     4081 aatttcatga ccaaacacgg aaatccaggt aacggacgtt atagaccaga ggattttaga
     4141 ccaaactcag cttacgtaaa tgtcaatatg atggcaggaa tttacggtgg gaatacgagt
     4201 caaggtgctc ctggttcatt atcgttcaaa cataatgcct tccgtatgtg gggttattat
     4261 ggatatgaca aaggtttcac tagttatgta tctagcaaat atcaaggtga agctgataaa
     4321 caaaaccagg gtagattagg tgatgatttc attatcaaaa aagtttcaaa caaccaattc
     4381 tcaaatcttg aagattggaa gaaatattgg tatcatgatg tgaaatccag agctgaaaaa
     4441 ggattcacag agattacaat tgatggacaa accattcaca actataatga actgaaagac
     4501 ttattcgaca aagctgtcac agaagacctc aagaaagctg gaaactactc aaatactgag
     4561 aatttgaaat ccaaagtctt caaagctctt cttaaaaaca cagacggttt ctttaatcca
     4621 ttgttcaaaa aagacat
//
LOCUS       DAVHLA010000083         4306 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVHLA010000083 DAVHLA010000000
VERSION     DAVHLA010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4306)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4306)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4306
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.083"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(356..859)
                     /locus_tag="VVO77_002110"
     CDS             complement(356..859)
                     /locus_tag="VVO77_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694045.1"
                     /translation="MKRLAIETITKPMKLRGISKGIAELDGQGLEIDLDNLEIDFGGE
                     SFDLARIPGTKGGYRYFFLCPDCGRRCRLLYKRYLYFSCGTCLDIHKSTLNRSKTDCQ
                     YYWELALKEARKVEPGWSPRRGGYMFDGFPERPKYMKRDRYHKHYKKFLKYIEKGDRF
                     WLNGLRL"
     gene            complement(928..1452)
                     /locus_tag="VVO77_002111"
     CDS             complement(928..1452)
                     /locus_tag="VVO77_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694046.1"
                     /translation="MTLKTFSDKAKTFNFTYEFKDQDTAQVAGSALMGYMIGTYEVPS
                     ISITYKNKGTLAAEYVEDKKLNYIFKRICDSFKGCYKQPEGDEAFEERYKRERVLQLK
                     ESEDFESLLNKVTDYELELLDYAERLLSDKPILMNSMTAFGTLEVLGNESINLFQKLD
                     VEGEYKGLADYSGQ"
     gene            complement(1967..3445)
                     /locus_tag="VVO77_002112"
     CDS             complement(1967..3445)
                     /locus_tag="VVO77_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase family protein"
                     /protein_id="HEU5694047.1"
                     /translation="MEVREQEHPPRTMKELENRIFKAGEEWRAEHTETKVNETTGDVT
                     EKVAMPQTFTVAKILSEIVTFTFISKSNIPDYSLLYIYDLDEGIYTASNDLFNLLCKT
                     FDVRIKPREWPQIKLMVRTLAKIRKPLESANLVPVKNGIIDLRTKELLPFSPKYVITS
                     KISTAYHAPKRVPTDREGKTFDDWLNSIACNDSELVTLFWQIILEAINSNHTRNKFAI
                     FYGDGNNGKGTFQRFLINLIGESNISALKPAQFAEKHNLETLVGKVCNIGDEAPNEYL
                     KNPSDLMSITSGDTVLVNPKGRPAFEATFKLFNIFSGNYIPNGGNKTKGWYRRIMIVP
                     FNADFNGEKEKPWIKNEFLANDEVLEYALYKAINQEPFTHFIEPKAVKGLLEEYQEEN
                     DYLLSWVKHEYMERGWHELDVVPVFILTRTLKHYAEDMGIAKPNVYGAGKDTIRHLQQ
                     LTPNKYQLKKARVRIEDYDKLDPYGFERQKLGRVNHAVTKTE"
     gene            complement(3489..4181)
                     /locus_tag="VVO77_002113"
     CDS             complement(3489..4181)
                     /locus_tag="VVO77_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001839244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase alpha helix C-terminal domain-containing
                     protein"
                     /protein_id="HEU5694048.1"
                     /translation="MPEKNGSYKRNNSSLIYRDLIFLDYDDIQGTTEDFIEAVSSALF
                     GYSYILYPTIKHSIEKPRFRLVVKSNNVMNEATYKQVVKEIADKIGLPFDMASLTWSQ
                     LQGLPVTTGDPATYQKIVEHGLDYPVPKVEPRAKQGTTERYKPRVSGQRSMTMRIIDT
                     LFNGFGDEGGRNVALTRFVGLLFNKWVDCDLETAYELTKIANSVTVEPLPIEELDRSF
                     SSIARAEYRKRG"
BASE COUNT         1126 a          969 c          753 g         1458 t
ORIGIN      
        1 cttccccgtg agaaaaaatg tacaatgacg gtgtgaagct catagaagtg cgtggggagg
       61 gagatatagc cactttctcg gcgttcgctc ggagttcaac acacataacc ctgacatttt
      121 ccaggcatat ttactgccac tacctaagca aaatctcacc ttttctaacc ctcggtaaac
      181 ctctctacct tgtggtaacc ttgtactttt tatatatgct acctcaccct taccgcaccc
      241 ttttttggaa cactctgctt acttaaccct tgatatatct agctttttta acattcaaac
      301 cgtctaatat gtagtatttg tttgttttgt aaattgcaca ctacttcata tcgtcctaca
      361 atctcaaacc attcagccaa aatctatccc ctttttcaat atacttcaaa aacttcttat
      421 agtgcttatg atacctgtca cgcttcatat actttggtct ttcagggaaa ccatcaaaca
      481 tatatccacc acgtctagga ctccaccctg gttctacctt tctagcttct ttcagtgcaa
      541 gctcccagta atattggcaa tccgttttac tgcggttcag ggtgctcttg tggatatcta
      601 gacaggtacc gcaactaaaa tacaaatacc gtttataaag caacctgcac cgtctaccac
      661 aatcagggca aagaaagaaa taacgataac cacccttagt tcctggtatt cttgctaaat
      721 caaatgactc tccaccaaaa tcaatctcta aattatccaa atcaatctct aaaccttgac
      781 cgtccaactc ggctataccc ttagatattc ctctcagctt cattggttta gtgattgttt
      841 ctattgctaa ccgcttcatt atttccccct atatggaaaa acccaaaact attgcctaaa
      901 tgtcaaaagg ggattgctcc cctgtgttta ttgaccagaa taatcagcaa ggcctttata
      961 ttcgccctct acgtccaatt tttggaatag gttaatactt tcattaccca gcacttccaa
     1021 cgtaccaaaa gcagtcatag agttcataag gataggctta tcagaaagca agcgttcagc
     1081 atagtctaat agttccagct cgtagtctgt aaccttattc agcaagctct caaagtcctc
     1141 tgactctttg agttgaagca cgcgctcccg tttataacgt tcttcaaatg cttcatctcc
     1201 ctctggttgc ttgtaacagc ctttgaaact gtcacaaata cgtttaaaga tatagtttag
     1261 tttcttatcc tccacgtact cagctgctag cgtcccttta ttcttgtaag tgattgaaat
     1321 agacggtact tcataagttc caatcatgta gcccatcaat gcactccctg ccacttgggc
     1381 ggtgtcttgg tctttaaatt cgtaagtgaa attaaatgtt tttgctttat ctgaaaatgt
     1441 ttttaatgtc atgttgtttt tcctctttct gtttttaggg tgtcactagt agttacacca
     1501 ttgcaagggg gtcagtacta tctaccccat tttgtttaaa tgttttagtg tttgtcaggt
     1561 actgctttta gttcgttaat ctttctttta catccgtcat gttccacttc ctctttttta
     1621 ttttaaggta aattatgtaa tatttgttaa tttgttgacc ttcttgttac ttttgttgac
     1681 cttctatgta acgtagttta gccttacagt tccaagggtt tagacaactt tgttaccatg
     1741 ttgaccttct tttgaagtcc ttgcccttat atataaaata tatttatttc atttacattc
     1801 ttgtttttaa aaagaaggta acaaggtcaa cataaaggct ataaaactag tgctatcaag
     1861 ggtttaggat gttgaccttc tttaaaacaa ggtcaacaag aaggtcaaca aattccgtaa
     1921 aaacccagtc atatcaatgg tttagagcat tatgagaagg tcaacattac tctgttttag
     1981 ttacagcatg atttactcga cccagttttt gtctctcaaa accatacggg tccagtttgt
     2041 cataatcttc aatcctaaca cgggcctttt taagctgata cttattaggt gttaactgtt
     2101 gtaggtgtct gatagtatct tttcctgccc cataaacatt aggcttggct atccccatgt
     2161 cctcagcata atgcttcagt gttctggtca gtataaaaac gggtaccacg tccagctcat
     2221 gccaacctct ttccatgtat tcatgtttaa cccatgaaag caagtagtca ttttcttcct
     2281 ggtattcttc tagaaggcct ttgactgctt tgggttcgat aaagtgtgta aaaggctctt
     2341 gattgatagc tttgtaaagt gcgtactcta atacttcatc attggccaaa aattcatttt
     2401 taatccaagg cttttccttc tccccgttaa agtcagcatt aaaagggaca atcataattc
     2461 tacgatacca gccttttgtc ttgttgccac cattggggat ataattccct gaaaagatat
     2521 tgaataactt gaaagtagcc tcaaaggctg ggcgtccttt ggggttgacc agtactgtat
     2581 cgccactagt gatactcatt aaatcagacg gatttttcaa gtattcattt ggggcttcat
     2641 ctccgatatt acaaacttta cctaccaggg tttctaagtt atgcttttca gcaaactgtg
     2701 caggttttaa ggctgatata ttgctttccc ctatcaggtt gataaggaag cgctgaaatg
     2761 ttcccttacc gttgttaccg tccccgtaga agatagcaaa cttatttcgg gtatggttag
     2821 agttgatagc ttcaaggata atttgccaaa acagtgtcac tagctcacta tcattacaag
     2881 cgattgagtt tagccaatca tcaaaagttt ttccctctct atctgttggg actcgtttag
     2941 gcgcgtggta tgccgtgctt atcttgcttg taattacata cttaggacta aaggggagta
     3001 actccttagt tcttaggtca ataatgccat tctttacagg tacaaggtta gcactctcta
     3061 aaggttttcg tatctttgcc aatgttctaa ccattaactt aatctgtggc cactctctgg
     3121 gtttaattct aacgtcaaag gtcttacaca aaagattgaa tagatcatta ctagcggtat
     3181 agataccctc gtctaaatca tagatataga gcaggctata atcaggtata ttgctcttgc
     3241 tgataaaagt aaatgtgaca atctcgctca gtatttttgc tactgtgaat gtctgaggca
     3301 tggcaacctt ttcggtaacg tcccctgtgg tctcatttac cttagtttcg gtatgttctg
     3361 ctcgccattc ttcaccagct ttaaagatac gattttcaag ctccttcatc gttctaggag
     3421 ggtgttcttg ctctctgacc tccatgattt cactttttag gttttctaat tcttctagtt
     3481 ctatggttct aacctctctt tctatattca gcccgtgcta tactactgaa actgcggtct
     3541 agctcttcaa taggcaatgg ttcaactgtc acactatttg ctatctttgt aagttcatag
     3601 gcggtctcta ggtcacaatc aacccactta ttgaagagta atcccacaaa gcgtgtcagc
     3661 gctacgttgc gccctccttc gtctccaaat ccgttgaaaa gcgtgtcaat aatcctcata
     3721 gtcattgacc tctggccact tactctaggt ttataacgct cagtagttcc ttgcttcgct
     3781 cttggttcaa ccttggggac tggataatca agtccatgct ctacaatctt ttgataagtt
     3841 gccgggtcgc ctgttgttac tggtagccct tggagttgtg accaggttaa actggccatg
     3901 tcaaagggta gcccaatctt gtcagcaatc tcttttacta cctgcttata ggttgcctcg
     3961 ttcatcacgt tgttagattt caccacaagg cgaaaacggg gcttttctat gctatgtttg
     4021 atagtcgggt ataagatata agagtagcca aacaaagcgc tagaaacggc ttctatgaag
     4081 tcctcagtcg tcccctgtat atcgtcataa tcaaggaaaa tcaaatcccg atagattaga
     4141 ctggagttgt ttcgtttgta actcccgttt ttctccggca taaccttacc acttaaacaa
     4201 tatggcgcct gggttctttt gtattcctcc gtatcagcac tttcagggac taccaaaggc
     4261 ttaaagcgtt caatgtactg gaacggctcc atcttatcaa atggat
//
LOCUS       DAVHLA010000084         4282 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVHLA010000084 DAVHLA010000000
VERSION     DAVHLA010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4282
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.084"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            607..1953
                     /gene="gdhA"
                     /locus_tag="VVO77_002114"
     CDS             607..1953
                     /gene="gdhA"
                     /locus_tag="VVO77_002114"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEU5694049.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVISFRVPWVDRDGKVQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGHLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            complement(2459..2629)
                     /locus_tag="VVO77_002115"
     CDS             complement(2459..2629)
                     /locus_tag="VVO77_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694050.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(2642..3220)
                     /locus_tag="VVO77_002116"
                     /pseudo
     CDS             complement(2642..3220)
                     /locus_tag="VVO77_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(3237..4042)
                     /locus_tag="VVO77_002117"
                     /pseudo
     CDS             complement(3237..4042)
                     /locus_tag="VVO77_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
BASE COUNT         1316 a          803 c          715 g         1448 t
ORIGIN      
        1 aaatcgttgt ttgattacag tctaaaagct ctataatctc tttataagat ttgcccatca
       61 gacgaaatat agtagattga aactagaata gtacacctct acttctaaaa cattgttaga
      121 aatcgatttg actgtcctga tcgatttgcc ctgttcttgt ttcgttttac tatagaacga
      181 tttgaaggcg tttatgatat ttagctgtac gagagtcttt taaaagtgtt ttgatggctt
      241 ggatttcttc tttagttgat ttcatatcac tattatataa tgctttttga ttttagtctg
      301 gtataaatat tgctttcctc caaaatggtc ataattttac tagcaaatct aacatatcac
      361 ggataaatta acaagtgatt tctgaattgc taaacatttt cttttcttat agcataccat
      421 actttaagat tttgtctttg agaaagatat ttccaagaaa aacgttcgtt tttttatcta
      481 ttttcaaaaa aaaccaaaaa ctgaattgaa agaattttta gaaaatttct gttttttctt
      541 tacagtgaaa aaaaattctg ctataatgtc ttatgtaata aaatatgaca ataaaaggag
      601 aacgatatga catctgctaa agaatatatc caaagcgtgt ttgaaactgt aaaagctcgt
      661 aacgggcacg aggctgaatt cctccaagct gttgaagaat ttttcaacac tttggaacct
      721 gtatttgaaa aacaccctga gtatatcgaa gaaaatatct tggcacgtat tactgagcct
      781 gagcgcgtga tttctttccg tgttccttgg gttgaccgtg atggaaaagt tcaagtaaac
      841 cgcggctacc gtgttcaatt caactcagct gttggaccat ataaaggcgg acttcgtttc
      901 cacccaactg taaaccaagg gattttgaaa ttcctcggat ttgaacaaat ctttaaaaac
      961 gtcttgactg gacttcctat cggtggaggt aaaggtggat cagacttcga tcctaaaggt
     1021 aaaacagatg ctgaagtgat gcgcttctgc caaagcttca tgactgaatt gcaaaaacac
     1081 atcggaccat cacttgacgt acctgctggt gatatcggtg ttggtggacg tgaaattggt
     1141 tacctttacg gtcaatacaa acgtcttaac caatttgatg ctggtgtctt gactggtaaa
     1201 cctcttggat ttggtggtag cttgattcgt ccagaagcaa ctggttacgg tttggtttac
     1261 tatactgaag aaatgctcaa agctaacggt aacagctttg ctggtaagaa agtcgttatt
     1321 tcaggttctg gtaacgttgc tcaatatgct cttcaaaaag caactgaact cggtgcaact
     1381 gttatttctg tttctgactc aaatggttat gtcatcgatg aaaatggtat cgacttcgat
     1441 cttttggttg atgttaaaga aaaacgtcgt gctcgtttga ctgagtatgc agctgaaaaa
     1501 gcaactgcaa cctaccacga aggtactgta tggacttacg ctggaaacta tgacattgct
     1561 cttccatgtg ccactcaaaa cgaaatcaac ggtgaagcag ctaaacgttt ggttgctcaa
     1621 ggcgttatct gtgtatctga aggtgccaac atgccgagcg accttgatgc catcaaagtt
     1681 tacaaagaaa atggtatctt ctacggacct gcaaaagctg ccaacgctgg tggtgtagcc
     1741 gtttcagctc ttgaaatgag ccaaaacagt cttcgcctct catggactcg tgaagaagtt
     1801 gatggccatc tcaaagacat catgacaaac atcttcaaca cagctaaaac gacttcagaa
     1861 acatacggtc ttgataaaga ctaccttgca ggagctaaca ttgctgcctt tgaaaatgta
     1921 gcaaatgcca tgattgcaca aggtattgtt taagatttat ttactcaatc ctcaatcact
     1981 acgattgggg atttttagct tgaattaaaa aattggaaaa tctaattaaa taaaatgaaa
     2041 tgaaataaaa actgaacaaa ttgattgcgg aattcaaacc aatttctaac atacttctag
     2101 aaattaattt gacttttcta atcgatttgt tcatatctta tttcaattta ctatacttac
     2161 ttaacccttt ttatactcaa tgaaaatcaa agagcaaact aggaagcgag ccgcaggctg
     2221 tacttgagta cggcaaggca aagctgacgt ggtttgaaga gattttcaaa gagtattaaa
     2281 caaaaagaaa aaccgctact cctaagaata gcgatttaat catgttttta agctactact
     2341 gtagttgctc tattatttaa gtgttatgaa taacttcaat atctttaaag ctttttgtta
     2401 gatttataat ttcaactata gccatctcta ctccttagtt tacagcaaaa aattatgctt
     2461 aattcttatt gtttttgtaa acaatcagcg aacccaatac tattccattc aacaagccta
     2521 aagaaatacc atattcaact ggaaaatcta aaaaaattgc aaacactatt ccaatcatca
     2581 cccctagtga ggctgttgtt aaaattacat attcattttc tttcttcatt ttctttacac
     2641 ctcatttcct ttttgtatat aagctgtagt actctccacc aagctccatt aagtacttat
     2701 gatttcctga ctcaacaatc ttaccacctt tcattacaaa aataatatcc gcatccttaa
     2761 tcgttgacaa tctatgagct acaattattt gagtacagcc ctgacttttt atatactttg
     2821 ttattctttc ctcattaata gtgtctaaag cactagttgc ttcatctaaa attacaatac
     2881 taggattatt tattaatgca cgtgccagtg ctatccgttg tctttgacca cctgaaatat
     2941 ttgaacccat ctctgagatg atagtattaa atttcatcgg catagccatg atttcatcat
     3001 agatttgaac tgctttacaa acttcctcta tcttttgtga agtaacttcg ttctttaaag
     3061 ttatattatc aagaatactt cggttcaata aaaatgaatc ctgtggaact actcctaaat
     3121 tttgacttaa tattttttta tctatttgat taatatttat accatcaaat aaaacttttc
     3181 ctgtatcaat cttatataat cctgatggta tttttgataa tagacttcct gcaaaactag
     3241 aatcctagtt catgattgat aataccagca ctcaaattca ttcgtaatcc aaagcgttta
     3301 cgatgatttc gataggttgt tgaaaacatt ttaaacgttt ttactttggc aaagatgttc
     3361 tcaaccttgc ttctatcctt agatagtgca tggttatagg ttttatcttc aactgttagc
     3421 ggcttgagtt tgctggattt acgtggaatt tgtgcttgag gatatatctt catgagccct
     3481 tgataatcac tgtcagccaa gattttacca gcttgtccga tatttctgcg actcattttg
     3541 aacaacttca tatcatgaca atagttcaca gcgatatcca aagaaataat tctcccttga
     3601 cttgtgacaa tcgcttgagt cttcatagcg tgaaatttct ttttaccaga ataattcgct
     3661 aattcttttt ttaggtcgat tgatttttac ttccgtcgca tcaatcatta ccgtgtcctc
     3721 agaactgaga ggagttcttg aaatcgcaac accacctttg aacaagagtt acttcaaccc
     3781 attggctccg acggattaag ttgctttcgt gaataccaag atcagccgca atttcttcat
     3841 aagttcgata ttctcgcaca tattgaagag tggccataag aaggtcttct aggcttaatt
     3901 taggttttcg cccacctttt gcgtgtttaa gttgataagc tgtttttaat acagctaaca
     3961 tctcttcaaa agtcgtgcgt tgaacaccaa caagacgctt aaatcgtgca tcggttagtt
     4021 gtttacttgc ttcataattc atagaactat tataccatat tttgtttcgc aggaagtcta
     4081 ttgaaaaatc tccagactag agaactcacg gatagttcct aatctggaga tttcttattt
     4141 gcacttttct tgtacaactt tagtccacgg taaataggcc tctaaaacct ctttgtttac
     4201 gagagtttcc tcgtttggaa gacattctag aagataggat agatatttct cgctatttat
     4261 actagactaa aatcaaaaag ca
//
LOCUS       DAVHLA010000085         4202 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVHLA010000085 DAVHLA010000000
VERSION     DAVHLA010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4202)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4202)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4202
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.085"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            371..598
                     /locus_tag="VVO77_002118"
     CDS             371..598
                     /locus_tag="VVO77_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694051.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            886..3783
                     /gene="nanA"
                     /locus_tag="VVO77_002119"
     CDS             886..3783
                     /gene="nanA"
                     /locus_tag="VVO77_002119"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HEU5694052.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTPE
                     LPKGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLDGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NRRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHNGKEYIILSNAGGPKRENGMVHLARVEENGELTWIKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWDFLSKDLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
BASE COUNT         1444 a          689 c          904 g         1165 t
ORIGIN      
        1 gtcagtctta tctacaacct caaaacagtg ttttgagcat catgcggcta gcttcttagt
       61 ttgctctttg attttcattg agtataaaaa cagatgagtt tctgttttct ttttatggac
      121 tataaatgtt cagctgaaac tactttcaag gacattatta tataaaagaa ttttttgaaa
      181 ctaaaatcta ctatattaca ctatattgaa agcgttttaa aaataaggta taataaattt
      241 actaacactt ataaaaagtg atagaatcta tctttatgta tatttaaaga tagattgctg
      301 taaaaatagt agtagctatg cgaaataaca gatagagaga agggattgaa gcttagaaaa
      361 ggggaataat atgatattta aggcattcaa gacaaaaaag cagagaaaaa gacaagttga
      421 actacttttg acagtttttt tcgacagttt tctgattgat ttatttcttc acttatttgg
      481 gattgtcccc tttaagctgg ataagattct gattgtgagc ttgattatat ttcccattat
      541 ttctacaagt atttatgctt atgaaaagct atttgaaaaa gtgttcgata aggattgagc
      601 aggaagtatg gtataaatag cataagctga tgtccatcat ttgcttataa agagatattt
      661 tagtttaatt gcagcggtgt cctggtagat aaactagatt ggcaggagtc tgattggaga
      721 aaggagaggg gaaaattggc accaatttga gatagtttgt ttagttcatt tttgtcattt
      781 aaatgaactg tagtaaaaga aagttaataa aagacaaact aagtgcattt tctggagtaa
      841 atgtcttatt tcagaaatcg ggatatagat atagagagga tcagtatgaa tcggagtgtt
      901 caagaacgta agtgtcgtta tagcattagg aaactatcgg taggagcggt ttctatgatt
      961 gtaggagcag tggtatttgg aacgtctcct gttttagctc aagaaggggc aagtgagcaa
     1021 cctctggcaa atgaaactca actttcgggg gagagctcaa ccctaactga tacagaaaag
     1081 agccagcctt cttcagagac tgaactttct ggcaataagc aagaacaaga aaggaaagat
     1141 aagcaagaag aaaaaattcc aagagattac tatgcacgag atttggaaaa tgtcgaaaca
     1201 gtgatagaaa aagaagatgt tgaaaccaat gcttcaaatg gtcagagagt tgatttatca
     1261 agtgaactag ataaactaaa gaaacttgaa aacgcaacag ttcacatgga gtttaagcca
     1321 gatgccaagg ctccagcatt ctataatctc ttttctgtgt caagtgctac taaaaaagat
     1381 gagtacttca ctatggcagt ttacaataat actgctactc tagaggggcg tggttcggat
     1441 gggaaacagt tttacaataa ttacaacgat gcacccttaa aagttaaacc aggtcagtgg
     1501 aattctgtga ctttcacagt tgaaaaaccg acaccagaac tacctaaagg ccgagtgcgc
     1561 ctctacgtaa acggggtatt atctcgaaca agtctgaaat ctggcaattt cattaaagat
     1621 atgccagatg taacgcatgt acaaatcgga gcaaccaagc gtgccaacaa tacggtttgg
     1681 gggtcaaatc tacagattcg gaatctcact gtgtataatc gtgctttaac accagaagag
     1741 gtacaaaaac gtagtcaact ttttaaacgc tcagatttag aaaaaaaact acctgaagga
     1801 gcggctttaa cagagaaaac ggacatattc gaaagcgggc gtaacggtaa accaaataaa
     1861 gatggaatca agagttatcg tattccagca cttctcaaga cagataaagg aactttgatc
     1921 gcaggtgcag atgaacgccg tctccattcg agtgactggg gtgatatcgg tatggtcatc
     1981 agacgtagtg aagataatgg taaaacttgg ggtgaccgag taaccattac caacttacgt
     2041 gacaatccaa aagcttctga cccatcgatc ggttcaccag tgaatatcga tatggtgttg
     2101 gttcaagatc ctgaaaccaa acgaatcttt tctatctatg acatgttccc agaagggaag
     2161 ggaatctttg gaatgtcttc acaaaaagaa gaagcctaca aaaaaatcga tggaaaaacc
     2221 tatcaaatcc tctatcgtga aggagaaaag ggagcttata ccattcgaga aaatggtact
     2281 gtctatacac cagatggtaa ggcgacagac tatcgcgttg ttgtagatcc tgttaaacca
     2341 gcctatagcg acaagggtga tctatacaag ggtgaccaat tactaggcaa tatctacttc
     2401 acaacaaaca aaacttctcc atttagaatt gccaaggata gctatctatg gatgtcctac
     2461 agtgatgacg acgggaagac atggtcagcg cctcaagata ttactccgat ggtcaaagcc
     2521 gattggatga aattcttggg tgtaggtcct ggaacaggaa ttgtacttcg gaatgggcct
     2581 cacaagggac ggattttgat accggtttat acgactaata atgtatctca cttagatggc
     2641 tcgcaatctt ctcgtgtcat ctattcagat gatcatggaa aaacttggca tgctggagaa
     2701 gcggtcaacg ataaccgtca ggtagacggt caaaagatcc actcttctac gatgaacaat
     2761 agacgtgcgc aaaatacaga atcaacggtg gtacaactaa acaatggaga tgttaaactc
     2821 tttatgcgtg gtttgactgg agatcttcag gttgctacaa gtaaagacgg aggagtgact
     2881 tgggagaagg atatcaaacg ttatccacag gttaaagatg tctatgttca aatgtctgct
     2941 atccatacga tgcataatgg aaaagaatac attatcctca gcaatgcagg tggaccgaaa
     3001 cgtgaaaatg ggatggtcca cttggctcgt gtcgaagaaa atggtgagtt gacttggatc
     3061 aaacacaatc caattcaaaa aggagagttt gcctataatt cgctccaaga attaggaaat
     3121 ggggagtatg gcatcttgta tgaacatact gaaaaaggac aaaatgccta taccctatca
     3181 tttagaaaat ttaattggga ctttttgagc aaagatctga tttctcctac cgaagcgaaa
     3241 gtgaagcgaa ctagagagat gggcaaagga gagatgggca aaggagttat tggcttggag
     3301 ttcgactcag aagtattggt caacaaggct ccaacccttc aattggcaaa tggtaaaaca
     3361 gcgactttcc taacccagta tgatagcaag accttgttat ttgcagtaga taaggaagat
     3421 atcggacagg aaattattgg tatagctaaa ggaagcatcg aaagtatgca taatcttcct
     3481 gtaaatctag caggtgccag agttcctggc ggagtaaatg gtagcaaagc agcggtgcat
     3541 gaagttccag aatttacagg gggagttaat ggtacagagc cagctgttca tgaaatcgca
     3601 gagtataagg gatctgattc gcttgtaact cttactacaa aagaagatta tacttacaaa
     3661 gctcctcttg ctcagcaggc acttcctgaa acaggaaaca aggagagtga cctcctagct
     3721 tcactaggac taacagcttt cttccttggt ctgtttacgc tagggaaaaa gagagaacaa
     3781 taagagaaga attctaaaca tttgattttg taaaaataga aggagatagc aggttttcaa
     3841 gcctgctatc tttttttgat gacattcagg ctgatacgaa atcataagag gtctgaaact
     3901 actttcagag tagtctgttc tataaaatat agtagattga aataagatgt gaacaactct
     3961 atcaggaaag tcaaattaat ttatagaaaa attttagcag tcaaggtgta ctgttataga
     4021 ttcaatatat tatgcgacta ttaaccttgt cttctcctaa aattgacttt cttgttttct
     4081 tatcttgtcc actcgaaaca agtattgtaa gaatttgatt atttttgaaa gtacttttaa
     4141 tatacttgat atagttaaaa aagatttgaa actaaattcc aaattagaaa aagacttgaa
     4201 at
//
LOCUS       DAVHLA010000086         3031 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVHLA010000086 DAVHLA010000000
VERSION     DAVHLA010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3031)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3031)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3031
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.086"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            30..548
                     /locus_tag="VVO77_002120"
     CDS             30..548
                     /locus_tag="VVO77_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU5694053.1"
                     /translation="MNFLHEQGYKVYTYTPLLIKEFAKSLSLRKTKTDKKDAHGIALK
                     LLSDPNREQFQHDNRQVELKILARHIHRLKKKQSDWKVQYTRCLDIIFPELDKIVGKH
                     SEYTYQLLTRYPNPQKRLEAGFDKLIEIKRLTASNSRAFCRALKSSPNHQIEIRNSLD
                     KTIDFSYSLSFS"
     gene            complement(514..1989)
                     /locus_tag="VVO77_002121"
     CDS             complement(514..1989)
                     /locus_tag="VVO77_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEU5694054.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVVELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            2696..3031
                     /locus_tag="VVO77_002122"
                     /pseudo
     CDS             2696..3031
                     /locus_tag="VVO77_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
BASE COUNT          947 a          668 c          546 g          870 t
ORIGIN      
        1 aagatactgg acattatgcc tttaatctac tgaacttcct gcatgaacaa ggatataaag
       61 tttacaccta cactcctttg ctcatcaagg aatttgccaa atcattatca cttcgcaaga
      121 ctaaaacgga taagaaagac gctcatggca tcgctcttaa acttctttct gaccccaatc
      181 gtgaacaatt tcaacacgat aatcggcaag tagaactaaa aatactggct agacatattc
      241 atcgtctcaa gaaaaaacag tctgattgga aagtacaata cactcgttgt cttgatatca
      301 tctttcctga gttggataaa atcgttggaa agcattcaga atatacctac caactcttga
      361 cacgctaccc taatcctcag aaaaggcttg aggcaggatt tgataagctg atagaaatta
      421 agcgattgac cgcttctaat tcaagggctt tttgccgtgc tctaaaatca tcgccaaatc
      481 atcaaattga aataagaaat agtttagata aaactattga cttttcttat agtttgtctt
      541 tctcttaata acgttgatat gattgacctc tggatcttcc gtcccttgga gggagcaacc
      601 acgttccttg gcgaattgga tatagtctac aatttctcgt gtaatgcgtt caccaggagc
      661 caagatagga atccctggag gatagcacat gacaaattct ccacagacct gtccaacaga
      721 ctcatctaag gtcaaacttt ttctctctga atagaaagct tcttgtggag acagcaccaa
      781 ctcgggctga atatattctc cagctattaa gtccttccca tctcgtgaat agagtctctt
      841 aatatcagcc agagcaccaa ccaagcgctc gatgtcttgg atgcggtcgc cgatggaaat
      901 ataagccaag atattgccga tatcaccaaa ctcgatctga atgtcgtatt cgtctcgcaa
      961 gaggtcataa acctcgatac ctgttaagcc tattccctga gtgtaaactg acaacttggt
     1021 tacatcaaaa tcacagaccg acacaccatc tattaactct tttgagtaag catagtaacc
     1081 gccaatggca ttgatttcat gacgagcgta ctcggatagc tcaacgactt cctcaaacga
     1141 ctctttacca cgaagggcca agttgcgacg tgaaatatcc aaactagcca tcaataagta
     1201 agaggcagat gtagactggg tcaggtttat aatctgacga acgtactcgg gattcatctg
     1261 ctccccgatt aaaagaagcg aactttgtgt caaactccca ccagacttat gcatggaaac
     1321 tgctgccata tcagctcctg catccatagc agaaattgga agtttaccag tgaaatgcaa
     1381 atgcgctcca tgggcttcat ctactaaaac catcatgcca gcttcatgag ccatttctgt
     1441 caaccccttt aggtctgaac agatgccgta gtaagtagga ttgttgatta ggatagcctt
     1501 agcatctgga tgatccttta tggcctgtgc tactcggtca ttttcaagac ctaaagcgat
     1561 accaatctta ggatctacac tcatctcgat atagatggga atggcaccac atagaaccaa
     1621 cgcattgata gcagatttat ggacatttcg tggcagaata atcttatctc ctgccttgca
     1681 ggttgccaga atcatagtct gcaccgatga agttgttcca ccaatcatta gaaaggcatg
     1741 gctagctcca aaagcatctg cagccagctc ctctgcatca cgaataatcg aaataggatg
     1801 gcctaaatta tccaagggtt tcatcgaatt gacatcaatg cctacacatt tttctcctaa
     1861 gagttcgaca agttctggat ttccccgtcc acgcttgtga cctggaacat caaagggaac
     1921 aatccttttc ttgcgtaact tcaccaaggc ctcataaatt ggggcttggt tttgatctaa
     1981 ctctttcaaa acatactcct ttcaatattt ttaggacctt atgaaaacta aggaactaaa
     2041 ggttgactca tgaaaaaaga gcaggttttc acctgctctg caatcttctg acgtgtttat
     2101 tttggtttct gttgagtatg tctgttcccg atgtttccta actctctagt agcaaatatt
     2161 acgtacttta ttgatcgttt cacaagatga cgtgtgcttt caccacacta aaaatttatg
     2221 aattaggaca agtgtcctaa catcaactta taaaagtagg cttttaaccc tatcaataat
     2281 gtggcttttc aaccacgctt cggcattcaa ccctgcctgt ccgtaggcat tttttactcg
     2341 ggtttatatt tgctagaaaa catcatctca ttttctaagc tttattacta tatcatgttt
     2401 ttaagaactt gtaaagtatt ttttgataaa aaacaaaaat ataatagatt gaaactagaa
     2461 tagtacacct ctgcttctaa aacattgtta gaaatagatt ttactgtcct gatcgatttg
     2521 ttctgttctt gtttcatttt actatatgtt cgtaaatgaa agttctataa tgaagttagc
     2581 cacccagtcc tcctaaaaat tagatggttc aactagctga tagctcttgt aggcataaga
     2641 aaacacctct gtgttatact tgttgttcaa ccacaaacac aagaaaggca cagagatgca
     2701 agacaattat actacaaaag ccaaacattt gacaatcgat agccgtcgct taatcgaaag
     2761 atggaaaaag aagggaaatc aaatagagaa attgcctctc tgcttggaaa agttcctcaa
     2821 actatccaca ctgaaatcaa gcgtgggaca gtccgacaat gtcttggaaa agggcgcttc
     2881 aaagaggttt attctgccga ctatgctcaa cagtcttatg aaaacaattg caagcgctcg
     2941 gtcaagaaat caagcgtgac caaggaacta aaggaaaaga ttctccacta tcataaccaa
     3001 aaattttcgc ctgataagaa acaggctagc a
//
LOCUS       DAVHLA010000087         2952 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVHLA010000087 DAVHLA010000000
VERSION     DAVHLA010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2952
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.087"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(85..1026)
                     /locus_tag="VVO77_002123"
     CDS             complement(85..1026)
                     /locus_tag="VVO77_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEU5694055.1"
                     /translation="MKQAKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINALFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(1004..2767)
                     /gene="aspS"
                     /locus_tag="VVO77_002124"
     CDS             complement(1004..2767)
                     /gene="aspS"
                     /locus_tag="VVO77_002124"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEU5694056.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEKEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSAEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETSKTN"
BASE COUNT          859 a          697 c          591 g          805 t
ORIGIN      
        1 agatagaact gacgaagtca gtaacataca tacggtaagg cgacgctgac gtggtttgaa
       61 gagattttcg aagagtatta atcactaatt atctatctca acaaatcttc ctagaatatg
      121 aacattttcc gagacagaga caaaggagct tggatccact tgtgtcataa tctgtttaaa
      181 ttcattaaac tctgcacgtg taatgacagt gattaaaact gcctttctct cgtgattata
      241 ggttccttct gcatcatgga tcatggttgc tccgcggtgc aattttttat ggattttttc
      301 aattaccttc tctggatgat ttgtcacaat catggcctgc atacgctttt gcttagtaaa
      361 gactgcgtct gtcacacggc tagagacaaa gatggtaatc atagaataaa gagcgtattt
      421 ccaaccaaag gtcaaacctg ctatcagcat gatagttcca tttaccaaga aagaaatact
      481 accaacattc ttacccgttt tcttgcgaat agtcaggctg acgatatccg tcccaccact
      541 ggagatattg tttcgaagag caaaaccaat ccccaaaccc ataacaacac ccccaaaaag
      601 ggcattgata atgggatcct ccgtcaaggt tgccacaggg acaaactgga taaagaagga
      661 actcatagat accgtgataa aggtaaagac ggtgaactta tggccaatct gataccaagc
      721 taagaccatc aaagggaagt taatggcgta gaagcttagc gaaatcggaa tatgaaaacc
      781 aaaccagtga ttactcaagg cagagataat ctgtgccaga cctgttgcac cactcgaata
      841 cacatgccct ggttggaaaa agaaattaac tgctactgct gataaaaaac catagaccag
      901 agaggccgaa atcttctcat catacttttc tcgagagata ctttgtaaga cacgtaaaat
      961 ttttatctga taagcaaagc ggcgcagata atagcgccac cgcttaattc gttttgcttg
     1021 tttcatcttc ttctacttgt aagctgagtt cctctagttg tttgagagcg actgttgatg
     1081 gagcttgtgt cattgggtca gttgccttgt tgttcttagg aaaggcaatg acttcacgga
     1141 tattttcttc tccagcaagc aacatgacaa aacggtcaag cccgatagcc aaaccaccgt
     1201 gtggtgggaa accatagtcc atggcttcaa gaaggaaacc aaactggtca ttggcttctt
     1261 cagctgagaa accaagagcc ttgaacatgc gttcttgaag gtctttttgg ttgatacgaa
     1321 ggctaccacc accaagctca taaccgttca agacgatatc gtaagcaatg gcacgaacct
     1381 tagccaaatc accttctaat tcgtgagcag tctcttcctg tggaagtgtg aatggatggt
     1441 gggcgctcat gtagcggcct tcttcttcag accattcaaa catcggccag tcaaccaccc
     1501 aaaggaagtt gaacttatca ttatcaatca agccaagctc tttagcaata cgtccacgaa
     1561 gggcacccag tgttgcatta gccacttcaa gcgtatccgc cacaaagaga accaagtcct
     1621 tatcttcaag agcaagcgct gttgtcaatt cttcttggat accagtcaag aacttggcaa
     1681 ctggtccgtt taattctcca tcaaccacct tgacccaagc aagacctttg gcaccatact
     1741 gtttggctac ttccgtcatc ttgtcgatgt ctttacgtga atagttgtcc gcagctcctt
     1801 tgaccacaat cgcttttaca gcaggtgctt ctgaaaagac tttaaagtct acacctttga
     1861 ccacttctgt caagtcctga agcaacatgt caaaacgagt atctggcttg tcagaaccgt
     1921 aaagagccat agcatcatcg tatttcatac gagggaacgg tagcgttact tcgatgcctt
     1981 ttgtttcctt catcacgcgc gcgatcaagc cttctgtaat atcttggatt tctttctcag
     2041 taaggaagga cgtttccaag tcgacctgag taaattcagg ctggcggtct ccacgcaagt
     2101 cctcgtcacg gaaacattta acgatttggt agtaacggtc aaaaccagca ttcatcaaga
     2161 gctgtttcgt gatttgtgga ctttgaggaa gagcgtaaaa atgcccctta ttaacacgag
     2221 acggcactaa ataatcacgc gccccttcag gcgttgactt agaaaggaat ggtgtctcca
     2281 cgtcgataaa ctccaactca tccaaatagt tgcggataga gtgggtcacc ttggcacgaa
     2341 gtttaagatt ttccaacatt tctggacgac gaaggtcaag gtaacggtaa cgcaaacgtg
     2401 tatcgtcatt tgcctcaatg ccatccttaa tctcaaatgg tgttgtctta gctgtgttaa
     2461 gcacaataag agctgtcacg tttaactcaa ccgcaccagt tggcaactta tcattggctt
     2521 gctcacgcgc agcgacctga ccagtcacct caataacaaa ttcgctacga aggctttcag
     2581 ctgttgccat aacctctgca gatacttttt cagggttgat aaccaactgc atgattcctt
     2641 cacggtcacg aagatcgata aagatcaaac caccaaggtc acgacgacgg ccaacccatc
     2701 ctttcaaggt tatttcttgt ccgatgtgtt cctcacgaac acgaccagca tacatactac
     2761 gtttcattat ttctctcctc ttttattctg ttactatttt accataaaag cgcaggctct
     2821 tcatgaaaat catcagaaaa gtttgccagt ctttaaaagt caggtgaaag ccctaaaaat
     2881 tagcgctaat actcttcgaa aatctcttca aaccacgtca gcgtcgcctt accgtaggta
     2941 tggttactga ct
//
LOCUS       DAVHLA010000088         2794 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVHLA010000088 DAVHLA010000000
VERSION     DAVHLA010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2794)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2794)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2794
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.088"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            <1..821
                     /locus_tag="VVO77_002125"
     CDS             <1..821
                     /locus_tag="VVO77_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU5694057.1"
                     /translation="EKVDEYAESYNRLEQLDKEFPDKLKKSILQYAMQGKLVEQDPND
                     ESVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQGDDNSYYEEVPCEIPESWEWVRL
                     NDITSYIQRGKSPKYSNIPIYPVIAQKCNQWSGFSIDLARFIDPETVHSYQKERLLRD
                     GDLMWNSTGLGTLGRLAIYHENKNPYGWAVADSHVTVIRVLSGVINCHFIYNFLSSPI
                     VQSVIEEKASGSTKQKELLTKTIKEYLIPLPPLPEQSRIVDKIEQFFAHIDALI"
     gene            878..1675
                     /gene="psrA"
                     /locus_tag="VVO77_002126"
     CDS             878..1675
                     /gene="psrA"
                     /locus_tag="VVO77_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HEU5694058.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
     gene            1686..2288
                     /locus_tag="VVO77_002127"
     CDS             1686..2288
                     /locus_tag="VVO77_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU5694059.1"
                     /translation="MVKLTTCYFCDYGSYYGNIPMNWVVIKIKDIFSINTGLSYKKGD
                     LSINKGVRIIRGGNIKPLEFSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIG
                     KFARIDKDYDGVVAGGFIFQLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQAL
                     YNIPKTTLSELLIPLAPFEEQELITQKVEKLFEKVNQLWK"
     gene            complement(2236..>2794)
                     /locus_tag="VVO77_002128"
     CDS             complement(2236..>2794)
                     /locus_tag="VVO77_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU5694060.1"
                     /translation="NKDETTSYPIYEIPKAWRYIKFASLVNFRIGKTPPRSEATFWGT
                     EIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIP
                     ATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPI
                     SNHEEMKRIISKVDLLFQKVSQLFE"
BASE COUNT          981 a          397 c          482 g          934 t
ORIGIN      
        1 tagaaaaagt agatgaatat gctgaaagtt ataatagact agaacagcta gataaagaat
       61 ttccagataa actaaaaaaa tctattcttc aatatgctat gcaaggaaaa ttagttgaac
      121 aagacccaaa tgatgaatca gtcgaagttt tacttgaaaa aatacgagca gaaaaacaaa
      181 aactctttga agaaggcaag attaaaaaga aagatttgga catttctatt gtttcccaag
      241 gagatgataa ctcttattat gaggaagtac cttgtgaaat accagaaagt tgggagtggg
      301 tgaggttaaa cgatataacc tcctacattc aaagagggaa gtctccaaaa tattcaaata
      361 ttcctatata ccctgtgatt gctcagaaat gtaatcaatg gtctggcttt tctattgact
      421 tagcaagatt tattgatccc gaaacagttc atagttacca gaaagaaaga ttactaagag
      481 atggtgattt aatgtggaat tcaacaggtc taggtacgtt aggacgatta gctatttacc
      541 atgaaaataa aaatccttat ggctgggctg ttgcagatag ccatgttaca gttataagag
      601 tcttatcggg agttattaat tgccatttca tctataattt tctttcctct cctattgttc
      661 agtcagttat tgaagaaaaa gcgtcgggta gtacaaaaca aaaagaatta ttaacgaaaa
      721 ctataaaaga atatttaatc cccctcccac cccttcctga acaatccaga atcgttgata
      781 aaatcgaaca atttttcgcc catattgacg cactaattta gtataatagt tttacgtgcg
      841 gtggaatttc tatcaaacat aagataggag ttttacgttg aaagattttg aattacattt
      901 gaagaaagct ggtttagctg aaaatactgt gcgttcgtac ctttatggtg ttcgattttt
      961 cttggagaat tacgaactca aaatggaaga tttatttgaa tacaaaggat atttattaga
     1021 caattttaaa cctaaaactg tcaatttgcg actacaagga gtaaataaat atctggcttt
     1081 tattggtcat gatgatttga aattaaaatt tgtcaaagta cagcaaaaac cgtttttaga
     1141 agatgtcatt agccatgctg attacctttt tcttaaacgt agtttgaaaa aagatggtat
     1201 tttaaaatgg cattttgtcg tttggttttt aggtgcaact ggggctcgtg taagtgaact
     1261 tattaaacta aaagtagagc atgtagaaat cggttatttt gacatttact caaaaggtgg
     1321 taaaattcgt agactgtaca ttcctaaaaa attaagaaat agttgtctta gttggttaga
     1381 atcagaaaat cgccgaagtg gttatttatt tttgaataaa tttaacgaac caattacagc
     1441 aagaggagtt gctcaacagt taaaaaatta tgctgataaa tacaaaatga atcctaaagt
     1501 aatttaccct cattctttta gacatttatt tgctaagaat tttttagcga agtataatga
     1561 tattgccttg cttgcagatt tgatgggaca cgaaagtata gaaactactc gaatttatct
     1621 aaggaaaaca gctactgaac aacaaaatat tgtagataaa attgttaatt ggtaaaaaat
     1681 aacaggtggt caaactgact acctgctatt tttgtgatta tggctcttat tatgggaaca
     1741 tacctatgaa ttgggttgtt ataaaaataa aagatatttt ttcaataaat acaggtcttt
     1801 cttacaagaa gggcgattta agcattaata aaggtgttag aattatacgt ggtggtaata
     1861 ttaagccttt agaattttct ctgttggata atgattacta cattgacaca caattcatct
     1921 cctctgagca agtttattta aaacataatc agctaataac acctgtatca acctctttag
     1981 aacatattgg aaagtttgca agaatcgata aagactatga tggtgttgtg gctggtggat
     2041 ttattttcca attaacacca ttcgaaagtt cagagattat ttcaaaattt ctattattta
     2101 acttgtcctc tccgttattt tataaacaat tgaaagcaat aactaaacta tcaggtcaag
     2161 ctttatataa tattcctaaa actacactaa gcgagctatt aattccgtta gctccttttg
     2221 aggaacagga acttattact caaaaagttg agaaactttt tgaaaaagta aatcaacttt
     2281 ggaaatgatt cttttcatct cttcatgatt agaaataggg attaataatt cggagatact
     2341 ggtactattt aatgttttcc ctttgatagc atcttttgaa tcacctaaag tagagataag
     2401 tggcaaaaat atcattaagt aatctctgat aatattttct ttattagcat aggggaatat
     2461 cgatataatg gcttcattat gagtggcagg aatatccaat atggcaactt ttccaataga
     2521 taatttaaaa ctcattaata aagttccttt aggtgaaatg tctattttct ttgattttaa
     2581 tgctaattta gaaatagatt ctctcgtatt agttacataa ccagatatag gcatatctga
     2641 tatagatacc cagggtattt cagttcccca aaaagtagct tcactgcgtg gaggagtttt
     2701 tcctattctg aagttaacta ggctagcaaa tttaatatat ctccatgctt ttgggatttc
     2761 atatatagga taagaggttg tttcgtcttt gttc
//
LOCUS       DAVHLA010000089         2789 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVHLA010000089 DAVHLA010000000
VERSION     DAVHLA010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2789)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2789)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2789
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.089"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            64..780
                     /locus_tag="VVO77_002129"
     CDS             64..780
                     /locus_tag="VVO77_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEU5694061.1"
                     /translation="MKKRYLVLTALLALSLAACSQEKAKNEDGAAKTEQTAKADGTVG
                     SKAQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELLKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(820..957)
                     /locus_tag="VVO77_002130"
     CDS             complement(820..957)
                     /locus_tag="VVO77_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694062.1"
                     /translation="MKIKEQTRKLAAGCSKYSFEIADKTDEVSSKHCFEVVNRTDAVS
                     R"
     gene            1089..1514
                     /gene="rplK"
                     /locus_tag="VVO77_002131"
     CDS             1089..1514
                     /gene="rplK"
                     /locus_tag="VVO77_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEU5694063.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            1722..2411
                     /gene="rplA"
                     /locus_tag="VVO77_002132"
     CDS             1722..2411
                     /gene="rplA"
                     /locus_tag="VVO77_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEU5694064.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
BASE COUNT          943 a          526 c          623 g          697 t
ORIGIN      
        1 taaaagatta gtcaaacgtt tatcgttaga agtagataaa ctattagaaa taaaggagta
       61 gaaatgaaaa aaagatacct agtcttgaca gctttgctag ccttgagtct agcagcttgt
      121 tcacaagaaa aagcaaaaaa tgaagatgga gcagctaaaa cagaacaaac agctaaagct
      181 gatggaacag taggaagtaa ggctcaagga gctgcccaga aaaaagcaga agtggttaac
      241 aaaggagact actacagcat ccaagggaaa tacgatgaaa tcatcgtagc caataaacac
      301 tatccattgt ctaaagacta caatccaggt gaaaatccga cagccaaggc agaattgctc
      361 aaactcatca aagcaatgca agaggcaggt ttcccgatta gcgatcatta cagtggtttt
      421 agaagttatg aaactcagac caagctctat caagattatg ttaaccaaga tgggaaggca
      481 gcagctgacc gttactctgc ccgacctggc tatagtgagc accagacagg cttggccttt
      541 gatgtgattg ggactgatgg tgatttggtg acagaagaaa aagcagccca atggctcttg
      601 gatcatgcag ctgattatgg ctttgttgtc cgttatctca aaggcaagga aaaggaaaca
      661 ggctatatgg ctgaggaatg gcacctgcgt tatgtaggaa aagaagctaa agaaattgct
      721 gcaagtggtc tcagtttgga agaatactat ggctttgaag gcggagacta cgtcgattaa
      781 tactcttcga aaatctcttc aaaccacgtc agcgtcgcct tacctactga ctgcgtcggt
      841 tctattcaca acctcaaaac agtgttttga gctgacttcg tcagttttat ctgcaatctc
      901 aaagctgtac tttgagcagc ctgcggctag cttcctagtt tgctctttga ttttcattga
      961 gtataaaaaa taaacttttc tcttgcaatt ccagataaat agtgtataat ggatgggtat
     1021 gtgaaaaaca tacttgtggg aggtaaaaat ctctaattac cgccaaaacc acaaaggagg
     1081 atttaaaaat ggctaaaaaa gtcgaaaaac ttgtaaaatt gcaaatccct gctggtaaag
     1141 ctacaccagc tccaccggtt ggacctgctc ttggtcaagc tggtatcaac atcatgggat
     1201 tcacaaaaga gttcaacgct cgtacagctg accaagctgg tatgatcatt ccagttgtta
     1261 tctcagttta cgaagacaaa tcatttactt tcgttacaaa aacaccacca gctgctgttc
     1321 ttttgaaaaa agctgcaggt gttgaaaaag gatcaggtac acctaataaa actaaagttg
     1381 ctacagttac tcgtgcacaa gtacaagaaa ttgcagaaac taagatgcca gatttgaacg
     1441 cagcaaacgt agagtctgca atgcgtatga tcgaaggtac tgctcgttct atgggattca
     1501 ctgttgttga ctaatcaata acacagtaga aaatctcaca gcagtctatt agttgctttt
     1561 catactaggc aagtgactga gccttgtact tgggtacagc aagggagctt aaggccgtag
     1621 gaagagaaaa atagtagact gaaaacccgc aagacttcat catttcgaga agtgacgtgg
     1681 gagatgaaaa tcgattgaac cacttacaag gagaatagaa aatggctaaa aaaagcaaac
     1741 aacttcgtgc tgctcttgag aaaatcgaca gcacaaaagc atacagtgta gaagaagctg
     1801 tagcacttgc aaaagaaact aactttgcaa aatttgacgc aactgtagaa gttgcttaca
     1861 acttgaacat cgacgttaaa aaagctgacc aacaaatccg tggagcaatg gtattgccaa
     1921 acggtactgg taaaacttca cgtgttcttg ttttcgcacg tggtgcaaaa gctgaagaag
     1981 caaaagctgc tggtgcagac tttgttggtg aagatgacct tgttgctaaa atcaacgacg
     2041 gttggttgga cttcgacgta gttatcgcta cacctgatat gatggctctt gttggacgtc
     2101 ttggacgtgt ccttggacca cgtaacttga tgccaaaccc taaaactggt actgtaacaa
     2161 tggatgttgc taaagcagtt gaagagtcta aaggtggtaa aatcacttac cgtgctgacc
     2221 gtgcaggtaa cgttcaagca atcatcggta aagtatcatt tgaagctgaa aaattggttg
     2281 aaaactttaa agctttcaac gaaacaatcc aaaaagcaaa accagctaca gctaaaggaa
     2341 cttacgtaac aaacttgact atcacaacta ctcaaggtgt tggtatcaaa gttgacgtaa
     2401 actcacttta atcagtagtt aaagtaatgt aaaaaagttg aagacactat gtctcaactt
     2461 tttttgatgt acgacgggca tgtcgtatat ctgaggtgta agtcctcggt gggcacctac
     2521 taccggtgaa cccaatagcg attcccaagt ctgactatcg tgaggtagcg gattaaaacg
     2581 gtctggggat agaccgtttt aagtctgacg ctggaaataa gaatcgtcag aggaagggat
     2641 agcgaaatcg tggctctacg aacaggaacg tgataataag gcgtatatag cggataaggt
     2701 atctggctgg ggcgaccact atcaattata ataaaatgaa ataagaatag gacgaatcgt
     2761 tcaggacagt caaatcgatt tctaacaat
//
LOCUS       DAVHLA010000090         2616 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVHLA010000090 DAVHLA010000000
VERSION     DAVHLA010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2616
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.090"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            220..534
                     /locus_tag="VVO77_002133"
     CDS             220..534
                     /locus_tag="VVO77_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694065.1"
                     /translation="MWVLVFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRSVDKKGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            544..750
                     /locus_tag="VVO77_002134"
     CDS             544..750
                     /locus_tag="VVO77_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU5694066.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            750..947
                     /locus_tag="VVO77_002135"
     CDS             750..947
                     /locus_tag="VVO77_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694067.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVTEWIEKKSKNLASEKGE"
     gene            950..1684
                     /locus_tag="VVO77_002136"
     CDS             950..1684
                     /locus_tag="VVO77_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEU5694068.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            1696..2337
                     /locus_tag="VVO77_002137"
     CDS             1696..2337
                     /locus_tag="VVO77_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU5694069.1"
                     /translation="MKLLKNLGWILLALLSFFFIYGFIQGLATASLALGASPYAVTLL
                     YVVLAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            2355..2585
                     /locus_tag="VVO77_002138"
     CDS             2355..2585
                     /locus_tag="VVO77_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694070.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
BASE COUNT          767 a          430 c          536 g          883 t
ORIGIN      
        1 agtcagtaac tatacctacg gcaaggtgaa gctgacgtgg tttgaagaga ttttagaaga
       61 gtattaatga tagataaagt ggtcaggaac ttactcctga cctttttctt ttgcaaaatg
      121 acaaaaatca taaacttttt gacaactata attgtcaaaa agaaaaagat gtgttacaat
      181 gaattcaagt taagaaatag gaagcagaaa ggagttataa tgtgggtact agtatttata
      241 ctatttatga ttttctttta ttctaataat tctaaaaaaa tcaagaaact agagaataaa
      301 atcaaaaaac ttgagcgaaa agagaaagga aacgcagaaa tgtcgagatt attgcaagaa
      361 atgattggaa aggaaccaat tataacggga gtgtatattg ggccagataa ctgggaagtt
      421 gtggatgttg acgaggaatg ggtcaaacta cgtagtgttg ataaaaaggg gaaagaaaaa
      481 ttcaagttgc aacgtattga agatatccaa accgttgaat ttgacggaga gtaggtgtgt
      541 aacatgcaac taaaaaatcg tctaaaagag cttcgagctc gcgatggtct caatcaaacc
      601 gacctagcca aactggcagg ggtttccaga cagaccatta gcctactaga acgggatgag
      661 tacaccccat ccattatcat tgccctgaaa atatctcaaa ttttcaacga aacagtcgaa
      721 tcggtatttc gtttggagga ggacgagtga tgaacaagta taaagtgatt tattatgtag
      781 tggtcatagc tttattagtc agcgtatttc tactgattgg gatggaccta agctggttta
      841 atccctatca aagcgaccaa tttgtttggg tctactttgc tctcatccca gtaactgaat
      901 ggattgaaaa gaaatccaaa aatctagcaa gtgaaaaagg agaatgaata tgaaaaagaa
      961 acgtagattg ttatttttga tgtctattgt cttggggggg ttcttgggca tgtttgtagg
     1021 gatgtttaag gcacgtgtcg aatcccacga aattatttta gatgtaaaag ccttgatgcc
     1081 atggatatca gctatttgtt tactgatagg tttcattagt atgtttttga ctttcaattt
     1141 cttaaagaaa agcagaaaat ttcattcctt gtatcaagag gaaatggatg acgatctgaa
     1201 tgaaacctat tatgtgcaaa tgtatcggaa tcttgagttt ggaaccattg cttttaatat
     1261 tacaggtgta gcgattccat tggctatttt tatttcatta agtgaggtga ttatattgca
     1321 tacaaaccct caaacatttt tcctttcttt cttactcttt gtggtattct tagtcgctca
     1381 aaaatctctt tttaaaacca ttgcgattgt tcgtcagttt gatttggaat ttttcgctac
     1441 accaaaggat gtcttgaact atataaattc ttatgatgaa ggggagcgtc aggctaattt
     1501 ggaacagagt tttcgaattt tattccaatt acaccaatat gtcttaccag ccttatatat
     1561 ttttcttatt atcatttctt tcttgacagg agagattcag ttactagctt tcttgcttgt
     1621 aggagccatc catgtttata tcaatgtgat gcagttacct atggtaaaac gttatttcaa
     1681 ataaaggagt tatctatgaa attacttaaa aaccttggct ggattcttct agcccttcta
     1741 tcctttttct ttatctatgg ctttattcag gggctcgcga ctgcgtcgct tgctttaggc
     1801 gcttcaccct atgctgttac tctactctat gtggtcttgg ctggagtata tgtgtacggc
     1861 atttacaaat ggtatcagaa agctcctgtt tatattgaga agagcggctt taaccgattt
     1921 atttggcttc ctgccttggt ttggttctta tctctggtcg ttcaattctt cttgccagat
     1981 gatccttcag taaatcagca aatagcgaca gacttgacct tgtctcaacc acttttctca
     2041 ttctttgctg tggttatttt tgctcctttg acggaagaga ttgtttttag agggatgtta
     2101 gcacgctatc tctttcctaa gcaggacaat agtaaacgaa ccctgatttt tcttctggta
     2161 tctagtcttc tatttgcctt gattcatttt ccaggtgatg tgcaacaatt ttttgtctat
     2221 tttagccttg gttttagttt gggtttggct tacattagca gaaaaggtct ggtctacagt
     2281 atttctcttc acgctttgaa taatttagtc ggctttttga tgattctcat gctataatag
     2341 agtcaggagg tcacatgaaa cgagtaattt tattagcagt gattcaggca gtcgttctat
     2401 ttttcatcat tggagcgcta gcttatgcct tcaaaggcga tttcttctat aactatctag
     2461 cagttgtctt tgctcctatt gcaggtgtac tgcgttttgg gacggcttac ataacggaaa
     2521 ttgtcttgcc tcgaaaggca gccgaaatcg ctgaaaagcg taaagcaggc aaaaattcaa
     2581 aataaaagag tccggtgaag ttcatcggat ttttgt
//
LOCUS       DAVHLA010000091         2408 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVHLA010000091 DAVHLA010000000
VERSION     DAVHLA010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2408)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2408)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2408
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.091"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(122..328)
                     /locus_tag="VVO77_002139"
     CDS             complement(122..328)
                     /locus_tag="VVO77_002139"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEU5694071.1"
                     /translation="MREYRTYEEIAADFGIHESNFIRRSQWVEVTLVQSGFTVSRTPL
                     SSEDTVMIDATEVKINRPKKTISE"
     gene            complement(511..687)
                     /locus_tag="VVO77_002140"
                     /pseudo
     CDS             complement(511..687)
                     /locus_tag="VVO77_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            1022..>2408
                     /gene="pcpA"
                     /locus_tag="VVO77_002141"
     CDS             1022..>2408
                     /gene="pcpA"
                     /locus_tag="VVO77_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HEU5694072.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGV"
BASE COUNT          840 a          368 c          390 g          810 t
ORIGIN      
        1 actcattttg aacaacttca tatcatgaca atagttcaca gtgatatcca aagaaacaat
       61 tctcccttga cttgtgacaa tcgcttgagc cttcatagcg tgaaatttct ttttaccaga
      121 atcattcgct aattgttttt ttagggcgat tgatttttac ttccgtcgca tcaatcatta
      181 ccgtgtcctc agaactgaga ggagttcttg aaaccgtaaa accactttga acaagagtta
      241 cttcaaccca ttggctccga cggataaagt tgctttcgtg aataccaaaa tcagccgcaa
      301 tttcttcata agttcgatat tctcgcacta ttgaagagtg ggcataagaa ggtcttctag
      361 gcttaattta ggttttcgtc caccttttgc gtgtttaagt tgataagctg tttttaatac
      421 agctaacatc tcttcaaaag tcgtgcgttg aacaccaaca agacgcttaa atcgtgcatc
      481 ggttagttgt ttacttgctt cataattttg tttcgcaggg agtctattga ctctttggta
      541 ggtgtcaatg tttttttcat ctatcccgag aattattttc ccgccatttg tatttgcaaa
      601 tgctgagtag gtttcccaga aagactctgg aagattgttt ttagcttttt tgtattctaa
      661 atcaacccct tcaaatttta agtccatatt tttcctttac atctgttttt tgtggttctg
      721 gtatttgttc aagttgagtg ataatatagc gaattgaatt tcgagagttt ttactcagtt
      781 aatttctttt ttaacccact ttaatttctt ttttaacacg ggttaaaaaa gaaattaaag
      841 tgggttaatt ttccttgact taaaatttaa aaatgatata ctgtgtttat ggagagatga
      901 caatttataa aatgtactac tctattctac tagataatga ttgaataaaa ctttttataa
      961 caacggctag caaagttata attttatatc tattagaaaa taaatatgta aggaaattta
     1021 aatgaaaaaa actacaatat tatcattaac tacagctgcg gttattttag cagcatatgt
     1081 ccctaatgaa ccaatcctag cagatactcc tagttcggaa gtaatcaaag agactaaagt
     1141 tggaagtatt attcaacaaa ataatatcaa atataaggtt ctaactgtag aaggtaacat
     1201 aggaactgtt caagtgggta atggagttac tcctgtagag tttgaagctg gtcaagatgg
     1261 aaaaccattc acgattccta caaaaatcac agtaggtgat aaagtattta ccgttactga
     1321 agtagctagt caagctttta gttattatcc agatgaaaca ggtagaattg tctactatcc
     1381 tagctctatt actatcccat caagcataaa aaaaatacaa aaaaaaggct tccatggaag
     1441 taaagctaaa actattattt ttgacaaagg cagtcagctg gagaaaattg aagatagagc
     1501 ttttgatttt tctgaattag aagagattga attgcctgca tctctagaat atattggaac
     1561 aagtgcattt tcttttagtc aaaaattgaa aaagctaacc ttttcctcaa gttcaaaatt
     1621 agaattaata tcacatgagg cttttgctaa tttatcaaat ttagagaaac taacattacc
     1681 aaaatcggtt aaaacattag gaagtaatct atttagactc actactagct taaaacatgt
     1741 tgatgttgaa gaaggaaatg aatcgtttgc ctcagttgat ggtgttttgt tttcaaaaga
     1801 taaaactcaa ttaatttatt atccaagtca aaaaaatgac gaaagttata aaacgcctaa
     1861 ggagacaaaa gaacttgcat catattcgtt taataaaaat tcttacttga aaaaactcga
     1921 attgaatgaa ggtttagaaa aaatcggtac ttttgcattt gcggatgcga ttaaacttga
     1981 agaaattagc ttaccaaata gtttagaaac tattgaacgt ttagcctttt acggtaattt
     2041 agaattaaaa gaacttatat taccagataa tgttaaaaat tttggtaaac acgttatgaa
     2101 cggtttacca aaattaaaaa gtttaacaat tggtaataat atcaactcat tgccgtcctt
     2161 cttcctaagt ggcgtcttag attcattaaa ggaaattcat attaagaata aaagtacaga
     2221 gttttctgtg aaaaaagata catttgcaat tcctgaaact gttaagttct atgtaacatc
     2281 agaacatata aaagatgttc ttaaatcaaa tttatctact agtaatgata tcattgttga
     2341 aaaagtagat aatataaaac aagaaactga tgtagctaaa cctaaaaaga attctaatca
     2401 gggagtag
//
LOCUS       DAVHLA010000092         2083 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVHLA010000092 DAVHLA010000000
VERSION     DAVHLA010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2083)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2083)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2083
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.092"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            112..258
                     /locus_tag="VVO77_002142"
     CDS             112..258
                     /locus_tag="VVO77_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694073.1"
                     /translation="MEQYTKRASALILTFNRGVITQDEFLEEFTKLREKVVKAVSEAK
                     NDKL"
     gene            245..394
                     /locus_tag="VVO77_002143"
     CDS             245..394
                     /locus_tag="VVO77_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694074.1"
                     /translation="MTNYDRAKRFYSRATYVLSDFLHGRIDEQEFRKQWQRLADKAVN
                     ETKKN"
     gene            734..1186
                     /locus_tag="VVO77_002144"
     CDS             734..1186
                     /locus_tag="VVO77_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694075.1"
                     /translation="MEETAYENLTRRIDRISAEMREIGEKTGLSRLSLLASQTKFIKE
                     ELSRLLWIELPELNDSHKIEAVSKSTTGIFFSPGIFEMDAMRKAFFKRQAKHFFENEA
                     DQQAYIEHTEKEYLGATVTLKDILFNSKNGTQKVNKGCLIEKFEEAMQ"
     gene            1183..1383
                     /locus_tag="VVO77_002145"
     CDS             1183..1383
                     /locus_tag="VVO77_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694076.1"
                     /translation="MTLDLGKMTQAEFDEVMADIKARNPNIFQLISDFLDRKVTLEEM
                     DEFLKMERAEQVEYIKNYQARA"
     gene            1385..1600
                     /locus_tag="VVO77_002146"
     CDS             1385..1600
                     /locus_tag="VVO77_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694077.1"
                     /translation="MNELDISNTQAAVLIVILIGLLLYLNHRDRKKSAQIERENQQTI
                     KTPSEDLNPEYGRYIQLAGVRVYGGMK"
     gene            1597..1890
                     /locus_tag="VVO77_002147"
     CDS             1597..1890
                     /locus_tag="VVO77_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694078.1"
                     /translation="MSYTMNLYPDIEKILDETYFTKEIFLATCLNNTIRIAVARGVLT
                     SQLLDKETKEVVCKTLDTIIENQKAILQGVASGQITFVNKSKGEEGLDESIRE"
     gene            1871..>2083
                     /locus_tag="VVO77_002148"
     CDS             1871..>2083
                     /locus_tag="VVO77_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU5694079.1"
                     /translation="MSLSENDKRVLRLIKVGAENSITGSEISLTTKLTERTVRDIIKR
                     LVVKHNIPIVGVRCGVFSGYFIPANKG"
BASE COUNT          792 a          361 c          455 g          475 t
ORIGIN      
        1 acagtcaagg cagaaaccag acaaaaagca gaacacgacg gcttgaaagc cttggacaga
       61 atcccagata aacattacgc cctactttat gacatgatgg aggggtaaca gatggaacaa
      121 tacacaaaaa gagcaagcgc cttaattctc acgtttaacc gtggagttat aactcaagat
      181 gaatttcttg aagaatttac aaaactaaga gaaaaggtag taaaagcagt aagtgaggca
      241 aagaatgaca aattatgata gagccaagcg attttacagc cgtgcaactt acgtcctgag
      301 cgactttctg catgggcgga tagatgaaca agaatttaga aaacaatggc aacggctagc
      361 agataaagcc gtaaacgaaa cgaagaaaaa ctaagaaaac cgaagagcag gcaagcaatt
      421 agaaaaggtt ttgaaaagca tagagcgcca actcttaaaa ctggtacttt ctcacgcttt
      481 caatttggcg agtctgagcg tgaggctagt ggcaagaaaa aaactgtata agaaacaact
      541 caaaaagacc cacgctcaga agtttggcga ccgagagcat gaggcatgtg acaggaaaaa
      601 ctgtataaga aacaaccatt caaaatcccc acactcgcca tcgctcaact ttgagtgtga
      661 ggatatcctg gatagtaaaa ggcattaaaa agcccttagg gcaactacac aacatagaaa
      721 cagaggtaaa aatatggaag aaacagcata cgagaattta actagacgta tagacagaat
      781 tagcgcagaa atgcgagaaa ttggcgaaaa aactgggctt agtagacttt cgttattggc
      841 aagtcagaca aaattcatca aagaagaatt atcccgttta ctttggattg aactccctga
      901 attgaatgac agccataaaa tcgaagcggt ctctaaaagc actacgggaa tctttttctc
      961 ccctggtatt tttgaaatgg acgctatgcg aaaagcattc tttaaacgcc aagctaagca
     1021 cttttttgag aacgaagcag accaacaggc gtatatagaa catactgaaa aggagtattt
     1081 aggggctact gtaaccttaa aagatattct ttttaactct aaaaatggaa ctcaaaaagt
     1141 aaataaaggt tgtcttatag agaagtttga ggaggcaatg caatgacact agacctaggc
     1201 aaaatgacac aagcagaatt tgatgaagta atggctgaca tcaaggcaag aaatccaaac
     1261 atttttcaac tgatttctga ttttttagat agaaaggtaa cactcgaaga gatggatgag
     1321 tttttgaaga tggagcgagc tgaacaagtg gaatatatta agaattatca agcgagggca
     1381 taacatgaac gaactagata taagtaacac acaggctgct gtcttaatcg tgattttgat
     1441 tggcttactg ctttatttaa accaccgaga ccgcaaaaaa agcgcccaaa ttgagcgaga
     1501 aaaccaacag acgataaaaa cacctagcga ggatttaaac cctgaatatg ggcgatatat
     1561 ccagcttgca ggggtaagag tttacggagg gatgaaatga gttacacaat gaatttatac
     1621 cccgatattg aaaaaatact agatgaaacc tattttacta aagagatttt tctagcaacg
     1681 tgcttgaata acacaatcag aatagcagta gccagaggag tgctaacatc tcaactttta
     1741 gacaaagaaa ctaaagaagt tgtttgtaaa accttggata caatcataga aaatcaaaaa
     1801 gctattttgc aaggggtagc gagcggacaa ataacctttg taaataaaag caaaggagag
     1861 gaggggttgg atgagtctat cagagaatga caagcgagtt ttaagactaa tcaaggtagg
     1921 ggctgagaac tccataacag ggtcagaaat tagcctgaca accaagctaa cagaaagaac
     1981 tgtacgtgac attatcaagc gtctagtagt taagcacaac atccctattg taggggttag
     2041 atgtggcgtt tttagtgggt actttattcc agcgaataaa ggc
//
LOCUS       DAVHLA010000093         1914 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVHLA010000093 DAVHLA010000000
VERSION     DAVHLA010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1914
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.093"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(385..777)
                     /gene="rpsI"
                     /locus_tag="VVO77_002149"
     CDS             complement(385..777)
                     /gene="rpsI"
                     /locus_tag="VVO77_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEU5694080.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(797..1243)
                     /gene="rplM"
                     /locus_tag="VVO77_002150"
     CDS             complement(797..1243)
                     /gene="rplM"
                     /locus_tag="VVO77_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEU5694081.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            1599..>1914
                     /locus_tag="VVO77_002151"
     CDS             1599..>1914
                     /locus_tag="VVO77_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEU5694082.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
BASE COUNT          554 a          379 c          352 g          629 t
ORIGIN      
        1 cttccccatt ctatggaatc ttgcattatc cataatatag tagattgaaa ctagaatagt
       61 acacctctac ttctaaaaca ttgttagaat tcgatttgac tatcctcgat ttgtcctatt
      121 cttatttcat attactataa aaataaggta aacttttcaa aaaagcacga aaaaagcacc
      181 cataaggtaa acttttgagt gctttgaaac attgatataa tcgtattgat taacgttttg
      241 aggcaactga ccttgtcagg ttgcagccac atttgtaagc gactaaagtc gcaacaactg
      301 tgtcaattgc accaatttag taagaaagta taaaaaaaga acaccccgaa aggtgctctg
      361 tataagtata gtaattcttt cgaattaacg tttactaaat tgtgatgctt tacgagcttt
      421 cttaagacct ggtttcttac gttcaacttt acgtgagtca cgtgtaagaa gtcctgcgcg
      481 tttcaatgaa tcgcggaagt ctgggtctac ttgaagaagg gcacgagcga taccgtgacg
      541 gatagctcct gattgaccag cgtatccacc acctacaacg ttaacgaaaa cgtcgtatga
      601 acctacagtt gaagtaactg cgaatggttg gttgatgaca agacgaaggt cagcgtgtgg
      661 gatgtactct tcaacatctt ttttgttaac agtgatttta ccagttcctg gaacaaggcg
      721 aacgcgtgca acagcgtttt tacgacgtcc agtacctgca tattgtgctt gtgacatact
      781 ttatttgttc ctttccttag ataagtcctg aaatgtcaag aacttctggt tgttgtgcag
      841 catgagtgtg ctcagctcca acaaatactt tcaacttcat accttgagcg cgtccaagtg
      901 tattgtgtgg aagcatacct ttaactgatt tctcaatcaa acgtactgca tttttagaac
      961 gaagttcacc tgcagagatt tgtttcaatc cacctgggtg gtttgagtga gtgtagtaga
     1021 ttttatcagt tgctttttta ccagtcaatt taactttttc agcattgata acaatcacga
     1081 agtcacctgt atcagtgtgt ggtgtaaatg ttggtttgtt ttttccgcga agtacgctag
     1141 caactactgc agaaagacgt ccaagtggta catcagttgc gtcaactacg taccatttac
     1201 gttcaacttg gcctggttta gccataaatg ttgttttgtt catgatttct cctatatata
     1261 gttcgatttt tgtttacggt gatgggtgtt ccttcccatc gaaaagtatt tggaaggttc
     1321 cggggccttt caaatggggt aaacaatacc gcctactatc ataccaaatt tcacccctaa
     1381 aagtcaatag atatgaaaaa tatttttcgg taacttctca aagtaactga aagttatata
     1441 atcaagttaa tttgggaatt tacctattaa cttcggtaga tttttaggaa ttttttccct
     1501 atttctccct gtaactaaaa tccttttcaa aaaatcacct tttcttgatt tttaatccta
     1561 tttgctgtat gataagggaa aagaaagggg acagagatat ggcttttacc aatacccaca
     1621 tgcgatctgc tagttttggc attgttacca gcttgcctga tgacatcatt gactcttttt
     1681 ggtatatcat cgaccatttc ttaaaaaatg tctttgaatt ggaagaagaa ctcgagtttc
     1741 aattgcttaa taaccaagga aagattacct tccacttttc aagtcaacac ctccctacag
     1801 ccattgattt tgactttaac catcctttcg accctcgtta tcccccaaga gtactggttt
     1861 tagacatgga cggtagagaa actatcctcc tcccagaaga aaatgaccta tttt
//
LOCUS       DAVHLA010000094         1465 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVHLA010000094 DAVHLA010000000
VERSION     DAVHLA010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1465)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1465)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1465
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.094"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            436..1146
                     /gene="deoD"
                     /locus_tag="VVO77_002152"
     CDS             436..1146
                     /gene="deoD"
                     /locus_tag="VVO77_002152"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEU5694083.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLGDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(1169..1402)
                     /locus_tag="VVO77_002153"
                     /pseudo
     CDS             complement(1169..1402)
                     /locus_tag="VVO77_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
BASE COUNT          419 a          270 c          314 g          462 t
ORIGIN      
        1 ggtttgaaga gattttcgaa gagtataaac agaaaggtag agcgcgtgtt ctaatttgaa
       61 cacgagtaga aaacttttct aaaaacaaaa acgaaaggat gggtaaactg tattcgctga
      121 actgaatacg ggcgactctc ctctaaatca aaattaagaa agaaaggaat tgaccccacc
      181 ctaaaagcag tgggaaaaag atagttggtc tagcgagcat cgctcactgc gcccaactcc
      241 tattttccct tcgctttttg acgggtttgg tatctttctc aatataaaat ataaaataaa
      301 gaaaggtaga gcgtgtgttt tgatttgaac acgagcggaa aactcggaaa atagataatc
      361 tgactgaaaa atcaggattt ctcgtcggct tcctaatttt cagtcgtttt cttctcgctc
      421 tttgtatcat aaattatgtc tatccatatt gctgctcagc agggtgaaat tgctgataaa
      481 attcttcttc ctggggatcc tcttcgtgct aagtttattg cggagaattt ccttggtgat
      541 gctgtttgtt ttaacgaagt gcgtaacatg tttggttaca ctggtactta caagggtcac
      601 cgtgtatctg tcatgggaac tgggatggga atgccatcta tttcgattta tgcgcgtgag
      661 ttaatcgtag actacggtgt gaagaaattg attcgtgtgg gaactgcagg ttctttgaat
      721 gaagaggttc atgttcgtga attagttttg gcgcaggcgg ctgcaaccaa ctcaaacatc
      781 gttcgtaatg actggccaca gtacgatttt ccacaaattg ctagctttga tttgcttgat
      841 aaagcctacc atatcgccaa agaacttggt atgactactc acgttgggaa cgttttgtca
      901 tctgatgtct tttactcaaa ttactttgaa aagaatatcg agcttggtaa atggggagtc
      961 aaggctgtgg aaatggaagc agcagctctt tactatcttg ctgcccaata ccatgttgat
     1021 gcgctagcta tcatgaccat ctctgatagc ttggtcaatc cagacgaaga cacaactgca
     1081 gaagaacgtc aaaatacctt cactgatatg atgaaggttg gtttggaaac cttgattgca
     1141 gaataattat agccaaaaag gaagcccttt atgaattgta ggacttcctt ttcttatcca
     1201 gaaattgatc tagctctctc tgatttcgaa gaatagtgac tttatgtgaa tattcttggc
     1261 aaagtttttg gtaattttct ttttgagttt tgctacgtcc atcccaaaga atccatctga
     1321 taaactccca gtcaaagcgt tcagggcaat ctgccgccat actttctctg acttttccac
     1381 ggtatttaag ataacgctta aagggctcta taatatttgt agtgggtaaa tcccttatag
     1441 atattatgga gcctattttt gtgta
//
LOCUS       DAVHLA010000095         1423 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVHLA010000095 DAVHLA010000000
VERSION     DAVHLA010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1423
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.095"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            110..259
                     /locus_tag="VVO77_002154"
     CDS             110..259
                     /locus_tag="VVO77_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694084.1"
                     /translation="MEAKTHFARFMRRGMELARQLHSKEIQRDEFDRAWKRLGDQIEN
                     ETKKN"
     gene            409..855
                     /locus_tag="VVO77_002155"
     CDS             409..855
                     /locus_tag="VVO77_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694085.1"
                     /translation="MDEFFKEFEEKLGSVEEKLDILSEWHLSKKHHGATEIAEDCRSA
                     ISQLWMQFYRLSETYKQQEADHETFLDANISNLLGELKKHDEFLATNSINLGKERPNW
                     LLFNYLNKAVRSFTDPNKLATDNTGNIWDYLRSLIIKDLKERGLLK"
     gene            852..1067
                     /locus_tag="VVO77_002156"
     CDS             852..1067
                     /locus_tag="VVO77_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694086.1"
                     /translation="MNELDISNTQAAVLIVILIGLLLYLNHRDRKKSAQIERENQQTI
                     KTPSEDLNPEYGRYIQLAGVNVWGGME"
     gene            1064..1357
                     /locus_tag="VVO77_002157"
     CDS             1064..1357
                     /locus_tag="VVO77_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694087.1"
                     /translation="MSYTMNLYPDIEKIPDETYFTKEIFLATCLNNTIRIAVARGVLT
                     SQLLDKETKEVVCKTLDTIIENQKAILQGVASGQITFLNKSKGEEELDESIRE"
     gene            1338..>1423
                     /locus_tag="VVO77_002158"
     CDS             1338..>1423
                     /locus_tag="VVO77_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU5694088.1"
                     /translation="MSLSENDKRVLRLIKVGAENSITGSEISL"
BASE COUNT          549 a          227 c          311 g          336 t
ORIGIN      
        1 acggtcaagg cggaaaccag acaaaaagca gaacacgacg gcttgaaagc cttggacaga
       61 atcccagata aacattacgc cctactttat gacatgatgg aggggtagga tggaagcaaa
      121 aacccacttc gctagattca tgcgtagagg catggagtta gcaaggcaat tacatagtaa
      181 agaaattcaa cgtgatgaat ttgatagagc ctggaaaaga ttaggcgatc aaatcgaaaa
      241 cgaaacgaag aaaaactaag aaaaccgaag tgcaggcaag caattagaaa aggttttgaa
      301 aagcatagag cgccaactct ttaaactggt actttctcac gctttcaatt tggcgagtct
      361 gagtgtgagg atatcctgga tagtaaaaga caaagaaggt aaagcaaaat ggatgaattt
      421 tttaaagaat ttgaagaaaa attaggcagc gtagaggaaa agctagatat tttgtcagag
      481 tggcatttat caaagaaaca ccacggagca acagagatag ccgaagattg tagatcagca
      541 attagtcagt tatggatgca attttataga ttatcggaaa cttataaaca acaggaagct
      601 gaccatgaaa catttttaga tgcaaacatc agcaacttac taggcgagtt aaagaaacat
      661 gatgaatttt tagcaactaa ttccatcaat ttagggaaag aacgcccaaa ctggttatta
      721 tttaactatt tgaataaagc tgttagaagt tttacagatc cgaataaact agcaacagat
      781 aacactggta acatttggga ttatctacgt agcctaatta tcaaggattt gaaagaaaga
      841 gggttattaa aatgaatgag ctagatataa gtaacacaca ggctgctgtc ttaatcgtga
      901 ttttgattgg cttactgctt tatttaaacc accgagaccg caaaaaaagc gcccaaattg
      961 agcgagaaaa ccaacagacg ataaaaacac ctagcgagga tttaaaccct gaatatgggc
     1021 gatatatcca gcttgcagga gtcaacgtat ggggagggat ggaatgagtt acacaatgaa
     1081 tttatacccc gatattgaaa aaataccaga tgaaacctat tttactaaag agatttttct
     1141 agcaacgtgc ttgaataaca caatcagaat agcagtagcc agaggagtgc taacatctca
     1201 acttttagac aaagaaacta aagaagttgt ttgtaaaacc ttggatacaa tcatagaaaa
     1261 tcaaaaagct attttgcaag gggtagcgag cggacaaata acctttttga ataaaagtaa
     1321 aggagaggag gaactggatg agtctatcag agaatgacaa gcgagtttta agactaatca
     1381 aggtaggggc tgagaactcc ataacagggt cagaaattag cct
//
LOCUS       DAVHLA010000096         1141 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVHLA010000096 DAVHLA010000000
VERSION     DAVHLA010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1141)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1141)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1141
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.096"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            <1..181
                     /locus_tag="VVO77_002159"
     CDS             <1..181
                     /locus_tag="VVO77_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEU5694089.1"
                     /translation="ISRLIDKLANPLERSVLRLFYLNVLEAWQVAEEIDRSKTTVYRI
                     KQEAIEHLSKVEGAN"
     gene            181..573
                     /locus_tag="VVO77_002160"
     CDS             181..573
                     /locus_tag="VVO77_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEU5694090.1"
                     /translation="MELDKFKTMMNVRERMTYFLRFQRMAGSENQVTIDEEAWKLVLP
                     YRWDLSGEHEKAIREGLEIFAQDINSIENKRARKYFIIHYCYMRKKTMSECVEMAATS
                     STSYHRYKQIAVLNFARIHQNGELEVYK"
     gene            627..785
                     /locus_tag="VVO77_002161"
     CDS             627..785
                     /locus_tag="VVO77_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694091.1"
                     /translation="MIEDFLIDLENIQLEDMEIDFNMDIDIDLNIDFEIDVDLDDLDL
                     TLLQKLEA"
BASE COUNT          371 a          181 c          261 g          328 t
ORIGIN      
        1 aatatctagg ctgatcgata agctggccaa tccgcttgag cgttctgttc tcaggctgtt
       61 ctacttgaat gttctcgaag cttggcaggt tgctgaagaa atagataggt caaagactac
      121 agtatatcga ataaagcagg aagctataga acacttgagc aaggtggaag gagcgaacta
      181 atggagctgg ataagtttaa aacgatgatg aacgtcagag agcggatgac ctactttcta
      241 cgtttccaga ggatggcagg aagtgaaaac caagttacga tagatgaaga ggcttggaaa
      301 cttgtcttac cttatcggtg ggatttgagc ggtgagcatg aaaaagcaat ccgtgagggg
      361 ttggagatat tcgcccaaga catcaacagt atagagaaca aacgagccag aaaatacttt
      421 attatccatt attgttacat gagaaagaaa acaatgagcg aatgcgtaga aatggcagct
      481 actagctcca ctagctacca ccgatataaa caaatagccg tcttaaattt tgcgagaatc
      541 caccagaacg gagagctaga agtgtataag taggcgtttg tggtgttttg ttgagaaatg
      601 ttgagattta agtgaggggg gatgacatga ttgaagattt tttgattgat ttggagaata
      661 tccaattaga ggatatggag atagatttta acatggatat agacatcgat ttaaacatag
      721 attttgaaat agatgttgac cttgatgatt tagatttaac cttactacaa aaattagaag
      781 cgtaaatgta ggctgaggct tcatattcgc ctccctattt cgcttggttt cgtaccggac
      841 gattaaaaca ccatggataa actagaagcc cttagaaacg aatcagaggg acttttgtga
      901 ggtcataatc ttataaacca cgcgcttcat ggtataatat acctatcagc aaccagcaat
      961 aaaaaaagca cgtttaaccg tgctagtttc ttgcctgctg aactcgtcat ttattgccct
     1021 tttgtggggc tttttttgtg gactttttga gaatttttaa gaacttttaa tgatttctaa
     1081 tcaaatgaaa tttttcaaaa agtcagtaat atcaagggtt taggcgcttt aaacaagttt
     1141 a
//
LOCUS       DAVHLA010000097         1117 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVHLA010000097 DAVHLA010000000
VERSION     DAVHLA010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1117)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1117)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1117
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.097"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            77..484
                     /locus_tag="VVO77_002162"
     CDS             77..484
                     /locus_tag="VVO77_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU5694092.1"
                     /translation="MARYGVYAVIPNPEQKQIVLVQEPNGAWFLPCGEIEAGENHQEA
                     LKRELIEELGFTAEIGTYYGQTDEYFYSRHRDTYYYNPAYLYEATSFKEVQKPLENFN
                     HIAWFPIDEAIQNLKRGSHKWAIESWKKQHKIG"
     gene            649..948
                     /locus_tag="VVO77_002163"
     CDS             649..948
                     /locus_tag="VVO77_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEU5694093.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKASVDEANIKTLYSEKLIGISIPIK"
BASE COUNT          398 a          225 c          189 g          305 t
ORIGIN      
        1 taataacgat actagataat gaggaaaatg caatggcaaa cccaactctc ggagaaaaaa
       61 agcgaataca gactatattg ctcgctatgg cgtatatgca gttatcccta atcctgaaca
      121 aaaacaaatt gttcttgttc aagaaccaaa tggtgcttgg ttcctaccat gtggagaaat
      181 tgaagcaggt gaaaatcatc aggaagccct aaagcgtgag ttgattgaag agcttggttt
      241 cacagcagaa attggtacct attacggaca aactgacgaa tatttctatt ctcgtcatcg
      301 tgatacctac tactacaatc ctgcctacct ctatgaagca acttctttca aagaagtaca
      361 aaagccacta gaaaacttta atcatattgc ctggttccct attgacgagg ctatccaaaa
      421 ccttaaacgt ggtagccata aatgggccat tgaatcttgg aaaaaacagc ataagattgg
      481 ctaatactct tcgaaaataa aattcaaacc acgtcagcgt cgccttaccg tactcaagta
      541 tagcctgcgg ctagcttcct agtttgctct ttgattttca ttgagtataa atcaagcgac
      601 tttattcaaa aagtgctata atagaattag aaaatcggag gaaatattat gaagcttatc
      661 aatacgacaa actcacactc gcaacttgta aaaagtcaac tagaaagtac cgatgcaacc
      721 cttgttgagg tttattctgc agggaataca gatgttattt ttacccaagc tccgcttcac
      781 tatgaaatcc tcatctcaaa caaacaccgt gctattcgtg agcctgaaat cgaaaccatt
      841 caagaatttt tcttgaaacg taaaattgat aaggcctctg ttgatgaagc caatatcaag
      901 acactctact cagagaaatt aattggaatt tcaatcccaa tcaagtaaga aaattgagta
      961 aaaactcgat ttgagagaaa gtccaataag tctttccata acaaaacgca tagtaacaag
     1021 agtttctaca cccactatta tacgttttta tcattttgaa atctgctgct aatcaatgaa
     1081 gaagcaaaga tcaaactaag cagctagtta caagtta
//
LOCUS       DAVHLA010000098         1008 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVHLA010000098 DAVHLA010000000
VERSION     DAVHLA010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1008)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1008)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1008
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.098"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(304..615)
                     /locus_tag="VVO77_002164"
     CDS             complement(304..615)
                     /locus_tag="VVO77_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694094.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(630..>1008)
                     /locus_tag="VVO77_002165"
     CDS             complement(630..>1008)
                     /locus_tag="VVO77_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
                     /protein_id="HEU5694095.1"
                     /translation="TGFYYGTPSENEQLFGARRKIPEYKFVAEVVSYDDAAQTATIRQ
                     RNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELLTIKVPQPVQSGDM
                     VRALKEGLINLYKEDGTSVTVRA"
BASE COUNT          315 a          196 c          173 g          324 t
ORIGIN      
        1 catatcgtaa aggtcgtatt tccaacggca tgactgagaa catccaccac ggttggcatc
       61 acgcatactc tagacgcaat tctaatcttt tagactttgc ataataactg ttaaacagtt
      121 gaaaattaac ccagttttaa caagtagtca aaataccaga taaaggaaaa aagtctttaa
      181 aatcttaaaa acgcatagta tcaggtattg aacaatcttg atattatgcg ttttattgtg
      241 ggaagattta cttcattttc tcttggaatt gagttttctc ctacttcaaa actagatgat
      301 ttgctattta aaatagcgtt ccttatgatt ttggcaacct ggattaaagc gagaaaaaca
      361 aaaggggcaa cttaagcttt ctttatattg cttatatgtt agtagtttta gacaaacacc
      421 acataaaata ggcttatcct gtatcaaaga taagggatac ggctcaaaag ggtgattttc
      481 taatgaatca tgacaccgat aacaagcata atacttttta caatcatagc attgtaaagc
      541 aataatatcc agcttgctat ggtaatgaat gcatcttgtt tgcttatcca ctaagaaacc
      601 ctgtgcctct atcatttcct tttcctttct taagctcgaa ctgtgacgct ggttccatct
      661 tccttataaa gattgatgag tccttctttt aatgcacgaa ccatgtctcc tgattgaacg
      721 ggttgaggca ccttaatagt caatagttcc attggatttg gagcgcggtc gattttattg
      781 cctttggcat catgcaaatc ttcaatatag gtttcaaaat gacggaaacc tggaccataa
      841 aactcaactt ggtccccttc gttaatgaca tttcgttgac gaattgttgc tgtttgtgcc
      901 gcatcatcat aagaaaccac ttcagcgaca aacttgtact caggaatttt acggcgagca
      961 ccaaacaact gctcattttc agatggtgta ccatagtaaa atcctgta
//
LOCUS       DAVHLA010000099         1005 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVHLA010000099 DAVHLA010000000
VERSION     DAVHLA010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1005
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.099"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            275..526
                     /locus_tag="VVO77_002166"
     CDS             275..526
                     /locus_tag="VVO77_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEU5694096.1"
                     /translation="MKEFQFERKQRFSLRPYAIGACSVLLGTSLFFAGMGAQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            514..804
                     /locus_tag="VVO77_002167"
     CDS             514..804
                     /locus_tag="VVO77_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694097.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
BASE COUNT          382 a          137 c          189 g          297 t
ORIGIN      
        1 ttatctacta cctcaaaaca gtgttttgag caacctgtgg ctagtttcct agtttgctct
       61 ttgattttca ttgagtacaa agagcttggc aacaggctct ttttgtattg cgtttattaa
      121 gaaaaacaaa aaacatcgat atacatttaa ctaaaaatta ttgtatgtta tctcccttaa
      181 ttaggaatga taagggaata actagaaaga tttgtgaata caaactattt ctgatataca
      241 aaatatacag taataatgaa tgatgggaga tgggatgaaa gaatttcaat ttgagagaaa
      301 gcagcgtttt tctttgaggc catatgcaat aggagcttgt tcggtcttgc taggaacgag
      361 tttatttttt gctggtatgg gtgctcagcc tgtacaggat acagaaacga gttcagcact
      421 aatttcaagt cattatttgg atgagcagga tttatctgaa aagctgaaat ctgagttgca
      481 atggtttgaa ttagaaaaca agcttttgaa cttatgggag cattaggtta ctatgaagga
      541 tttgttcctt atgtttcaaa tcaatacaaa aaccaagctg aagaagaagg caaaccgcta
      601 tctgataaat atattttcga aaaaatctta ggaaaaacat atgcagcctt caaaaaagat
      661 caaattaatg agcgtgtcga gaaattaggt aagttaaaac ctattacaat aaattacaac
      721 ggaaaatcag aagtaattga tagtaaagaa aaattacaag agcttatgaa taaagccgtt
      781 aaagacgaag tggctcaaat atagtaaaat gaaataagaa caggataaat cgatcaggac
      841 agtcaaatcg atttctaaaa atgttttaga agtagaggtg tactattcta gtttcaatat
      901 actataaaat caggcaatac cacggctaaa aagtttgagt ttatcgaaac accagtgcaa
      961 aaactgaaaa aagcgattta taaagctcat ctcaaagatt cagat
//
LOCUS       DAVHLA010000100          919 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVHLA010000100 DAVHLA010000000
VERSION     DAVHLA010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 919)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 919)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..919
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.100"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            146..310
                     /locus_tag="VVO77_002168"
     CDS             146..310
                     /locus_tag="VVO77_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694098.1"
                     /translation="MKKKILIIFVLYLIMSIFLYPLRESAWYQLFYTIAYVIAVMIYF
                     AINKKKGEKK"
     gene            307..711
                     /locus_tag="VVO77_002169"
     CDS             307..711
                     /locus_tag="VVO77_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000846948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEU5694099.1"
                     /translation="MKTFLAKKRNIFLARLFLGQLPLLVSTYLFLSRQFLNFSVVFQF
                     LLVVINLASILVTVYLTREMRIREFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITA
                     GESYQQIIAYIGAVLCLIIMLLLMWGLKYYKK"
BASE COUNT          273 a          139 c          161 g          346 t
ORIGIN      
        1 atgcttgctt ttttaatttt tacaattcaa gaggttttga tgaccattta tgatttgagt
       61 gatccaaggt caaaataagt gctatactag cagtgtaaat gttcttgctc aactaagata
      121 aatcgcacat ttaggaggaa atcttatgaa gaaaaaaata ctgattattt tcgttctgta
      181 tctaatcatg tccatctttc tatatccgct tagggagagt gcttggtatc agctatttta
      241 taccatagcc tatgtgattg cagttatgat ctattttgct atcaataaaa agaaaggaga
      301 aaagaaatga aaacttttct tgctaaaaaa cggaacatct tccttgcgag attgttctta
      361 ggtcagttgc ccttgcttgt ttctacttat ctatttctat ctcgtcagtt tttaaatttt
      421 tccgtagttt tccaatttct tttagtagtt attaacttgg cttctatttt ggttactgtt
      481 tatctcacta gggaaatgag gataagagag tttgaagatg atgatttggt tagtcctaga
      541 accaatcaac ttatgttcat cggcttgaca ggttttatgt ctattatttg tttgtataga
      601 ggtatcacag caggagaatc ctaccaacaa ataatcgctt atattggcgc tgttctctgc
      661 ttaatcatca tgcttctgct catgtggggc ttgaagtatt ataaaaagta gagcttaatg
      721 aagtataaaa gaaaagggta agtgtttttg caatacttac ccttttataa tagattccct
      781 gcgaaacaaa atatggtata gtatagtaga ttgaaactag aatagtacgc ctctatttct
      841 aaaacattgt tagaaatcga tttgactgtc ctgatcgatt tatcctgttc ttatttcatt
      901 ttactatagt tctatgaat
//
LOCUS       DAVHLA010000101          717 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVHLA010000101 DAVHLA010000000
VERSION     DAVHLA010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 717)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 717)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..717
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.101"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            <1..>717
                     /locus_tag="VVO77_002170"
     CDS             <1..>717
                     /locus_tag="VVO77_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694100.1"
                     /translation="KTVGAVIEKLPENHVTGQKECYRLENNSTLTFNLEPDFSSRLYQ
                     KVTFSAWIKYENVVQGRNFWNVFNCFKHYLFRKNSETGVQSGPDYATLGMYKGSADWK
                     YITFTYDYSEKTNFDQLKTSLRFNLEGATSGTAWVTGIKVEIGSVATDWSPAPEDADG
                     LITEAKATFERTAQGLRTDLSAIQEYVNKDGQRQEALQRYTREESTRQATAVRELVNR
                     DFVGKATYQEDVKGINQRIE"
BASE COUNT          229 a          128 c          173 g          187 t
ORIGIN      
        1 ccaagacggt tggagctgta attgaaaaat tacctgaaaa ccatgtcaca ggtcaaaaag
       61 aatgttatag gttagagaac aactctactt taacgttcaa ccttgaacca gatttcagct
      121 caaggttgta tcaaaaagtt acttttagcg cttggatcaa gtacgaaaat gtagtccaag
      181 gtcgaaactt ttggaatgta tttaattgct tcaaacatta tctttttaga aaaaatagtg
      241 agaccggagt acagagtggt ccagattatg ctacgcttgg tatgtataaa ggttcggcag
      301 attggaaata tattacattc acttatgact actctgaaaa aacaaatttt gatcaattga
      361 agacatcatt gcgattcaat cttgaaggtg ctacaagcgg tacagcttgg gtaacaggaa
      421 tcaaggttga aatcggtagt gtggcgacgg actggagtcc tgcgcctgag gacgctgatg
      481 gtctcatcac tgaagctaag gctacctttg agcggacagc tcagggcttg cgaaccgact
      541 tatcagctat tcaggaatat gtaaataaag acggtcagcg acaggaagcc ctacagcgct
      601 atactcgtga ggagagcacg agacaagcga cagcagtccg tgagctggtc aatcgtgatt
      661 tcgttggtaa ggctacttat caagaagatg ttaagggtat caatcagagg attgaag
//
LOCUS       DAVHLA010000102          556 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVHLA010000102 DAVHLA010000000
VERSION     DAVHLA010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..556
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.102"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            62..385
                     /gene="tnpB"
                     /locus_tag="VVO77_002171"
                     /pseudo
     CDS             62..385
                     /gene="tnpB"
                     /locus_tag="VVO77_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
BASE COUNT          173 a           97 c          102 g          184 t
ORIGIN      
        1 taattcccca acttccagta tactagataa aaaataatta tcggaggaaa ggtattgtac
       61 tatgataatt caactaagtg atttaggtca agttcacctt gtttgtggca agacagatat
      121 gaggtaggga atagactcat tagcctatgt agttaaaacc cactttgaat tggattcttt
      181 ctccggtcaa gtctttctct tttgtggtgg acgtaaagac cgctttaaag ccctttactg
      241 ggatggtcaa ggattttggc tactatataa acgctttgag aacggaaaac tgacttggct
      301 aagtacagaa aaggatgtca aagctctcgc acctgaacaa gtagattggc ttatgaaggg
      361 cttttctatc actccaaaaa tatagtagat tgaaactaga atagtacacc tctgcttcta
      421 aaacattgtt agaaatcgat ttgattgtcc tgttcttatt tcattttact ataaatccat
      481 cagaaagttg tgatttctat tgaaatgagg actttctttt tacactcatc tgctttcaaa
      541 aagcattcta gtccat
//
LOCUS       DAVHLA010000103          499 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVHLA010000103 DAVHLA010000000
VERSION     DAVHLA010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..499
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.103"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            <1..>499
                     /locus_tag="VVO77_002172"
     CDS             <1..>499
                     /locus_tag="VVO77_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEU5694101.1"
                     /translation="EIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHSHWIK
                     KDSLSEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKGAEAIYNRVKAAKKVPLDRMP
                     YNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVKYYVEHPN
                     ERPHS"
BASE COUNT          161 a          104 c          113 g          121 t
ORIGIN      
        1 atgagattca agtagccaag ttggcaggca agtacacaac agaagacggt tatatctttg
       61 atcctcgtga tataaccagt gatgaggggg atgcctatgt aactccacat atgacccata
      121 gccactggat taaaaaagat agtttgtctg aagctgagag agcggcagcc caggcttatg
      181 ctaaagagaa aggtttgacc cctccttcga cagaccatca ggattcagga aatactgagg
      241 caaaaggagc agaagctatc tacaaccgcg tgaaagcagc taagaaggtg ccacttgatc
      301 gtatgcctta caatcttcaa tatactgtag aagtcaaaaa cggtagttta atcatacctc
      361 attatgacca ttaccataac atcaaatttg agtggtttga cgaaggcctt tatgaggcac
      421 ctaaggggta tactcttgag gatcttttgg cgactgtcaa gtactatgtc gaacatccaa
      481 acgaacgtcc gcattcaga
//
LOCUS       DAVHLA010000104          415 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVHLA010000104 DAVHLA010000000
VERSION     DAVHLA010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..415
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.104"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            1..415
                     /locus_tag="VVO77_002173"
                     /pseudo
     CDS             1..415
                     /locus_tag="VVO77_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT          131 a           75 c           95 g          114 t
ORIGIN      
        1 ctaaattaag cctagaagac cttcttatgg ccactcttca atatgtgcga gaataccgca
       61 cttatgaaga aattgcggct gattttggtg ttcacgaaag caacttactc cgtcggagcc
      121 gatgggttga agtaactctt gttcaaagtg gtgttacgat ttcaagaact cctctcagtt
      181 ctgaggacac ggtaatgatt gatgcgacgg aagtacaaat caatcgccct aaaaaaagaa
      241 ttagcgaatc attctggtaa aaagaaattt cacgctatga aggctcaagc gattgtcaca
      301 agtcaaggga gaattgtttc tttggatatc gctgtgaact atagtcatga tatgaagttg
      361 ttcaaaatga gttgcagaaa tatcggacaa gctggtaaaa tcttggccga cagtg
//
LOCUS       DAVHLA010000105          372 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVHLA010000105 DAVHLA010000000
VERSION     DAVHLA010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..372
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.105"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(<1..>372)
                     /locus_tag="VVO77_002174"
     CDS             complement(<1..>372)
                     /locus_tag="VVO77_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU5694102.1"
                     /translation="ILPHSAYSETLYQAGSWSHKRRVCQFSERKEGNLFYDVISLVTN
                     MTSGTSQDQFQLYRGRGQAENFIKEMKEGFFGDKTDSSTLIKNEVRMMMSCIAYNLYL
                     FLKHLAGGDFQTLTIKRFRHLF"
BASE COUNT          106 a           74 c           85 g          107 t
ORIGIN      
        1 aaaaagatgg cggaagcgtt tgattgttaa agtttggaag tcacctccag ctagatgttt
       61 gagaaaaaga tagagattgt aggcgataca gctcatcatc atacgaactt cgtttttgat
      121 taaggttgaa ctatccgttt tatcgccaaa aaatccctcc ttcatctcct tgatgaaatt
      181 ctcggcttga ccacgtccac gataaagctg aaactggtct tggcttgttc cactcgtcat
      241 atttgtaacg agagaaataa catcgtagaa caagtttcct tcttttcgtt cagagaactg
      301 gcagacacga cgcttgtgcg accaagatcc tgcttgatag agagtttctg agtaggcgga
      361 gtggggcaag at
//
LOCUS       DAVHLA010000106          361 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVHLA010000106 DAVHLA010000000
VERSION     DAVHLA010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..361
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.106"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            196..>361
                     /gene="blpU"
                     /locus_tag="VVO77_002175"
     CDS             196..>361
                     /gene="blpU"
                     /locus_tag="VVO77_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEU5694103.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAARGLQ
                     LGIKTRTWQGA"
BASE COUNT          144 a           40 c           81 g           96 t
ORIGIN      
        1 ggaagtctaa tagtaaaaaa gtgattagaa aacatctttt ttaaaaatag agatgatttt
       61 gaaacaaaaa agctaattca agacgtttcg atgccaattc aagatttgga tgaaaaaaat
      121 taatagatac tgttatacta aacttgtcaa gtttgtaaca agacaaatat taaaaataaa
      181 aaagaggtat tcgttatgaa tacaaaaaag atgtcacaat ttgaaattat ggatactgag
      241 atgcttgctt gcgttgaagg tggcggatgc aattggggag attttgccaa agcaggtgtt
      301 ggaggaggag cagcacgagg tcttcagcta ggaattaaaa caagaacatg gcaaggtgca
      361 g
//
LOCUS       DAVHLA010000107          321 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVHLA010000107 DAVHLA010000000
VERSION     DAVHLA010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.107"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(<1..217)
                     /locus_tag="VVO77_002176"
     CDS             complement(<1..217)
                     /locus_tag="VVO77_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEU5694104.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIR"
BASE COUNT           96 a           74 c           39 g          112 t
ORIGIN      
        1 tacggatata gtctaaaatt cgatttcgaa acttggtttt gaaatatttc cttaaacgtg
       61 gaatatcgtc taccagtcct tcttctctac taatcaattc atgtaagcag agcatgcctt
      121 cttggtccca atccgataat tcccataaat gaaggtaata ttcatttcta cacttataca
      181 cagtcccttg gacttcttca tacaattctt taatcataat tttccccttt ctagatacag
      241 tctaacagat tagaaaacac atttgttcca ttttctccat tctgttccct ttagctccta
      301 aactgcacaa aaaagagagg c
//
LOCUS       DAVHLA010000108          283 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVHLA010000108 DAVHLA010000000
VERSION     DAVHLA010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 283)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 283)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..283
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.108"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            <1..>283
                     /locus_tag="VVO77_002177"
     CDS             <1..>283
                     /locus_tag="VVO77_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU5694105.1"
                     /translation="YEKVFSNSFDKHIDARMLSFRLVKHLERAGCPRFTFHAFRHTHA
                     SILLNAGLPYKEIQTRLGHAKLSMTMDIYSHLSKDNQKNATSFYEKAIEK"
BASE COUNT           92 a           61 c           48 g           82 t
ORIGIN      
        1 tatgagaaag tattctctaa tagctttgat aagcatatag acgctagaat gcttagtttc
       61 aggttagtaa aacatttgga acgtgctgga tgccctcgtt ttacgttcca cgccttccgc
      121 cacactcatg ctagtatctt gctcaatgct ggactacctt acaaagagat acaaacacgg
      181 ctcggtcatg caaaactttc tatgaccatg gatatttata gccacctatc caaagacaat
      241 cagaaaaatg ctacttcatt ttatgaaaaa gccattgaaa aat
//
LOCUS       DAVHLA010000109          279 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVHLA010000109 DAVHLA010000000
VERSION     DAVHLA010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 279)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..279
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.109"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            84..>279
                     /locus_tag="VVO77_002178"
     CDS             84..>279
                     /locus_tag="VVO77_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694106.1"
                     /translation="MTPEQVKETLEGVKWINKEIEGLYLELAALESGIIKKQELSNTR
                     VQTSRVNTAENNLISVLKLKE"
BASE COUNT          118 a           46 c           63 g           52 t
ORIGIN      
        1 agagaaaacg aaaaaaagcc aaggcactcc gcctcagcta atagttctca caaagactat
       61 tatatcatac aggaggccga gacatgacac cagagcaggt aaaagaaaca ctagagggcg
      121 ttaagtggat aaacaaagag atagaaggct tatatttaga gcttgcagct ttagaaagtg
      181 gtattatcaa aaagcaagaa ctaagcaata ccagagtaca aacaagcagg gtaaatacgg
      241 cagagaataa tcttataagt gttctgaagc taaaagagg
//
LOCUS       DAVHLA010000110          274 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVHLA010000110 DAVHLA010000000
VERSION     DAVHLA010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 274)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 274)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..274
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.110"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            <1..>274
                     /locus_tag="VVO77_002179"
     CDS             <1..>274
                     /locus_tag="VVO77_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU5694107.1"
                     /translation="FKDIAEKLPELEGKRLEEITKVLGYRNLESCRTNLCKLKQNNRL
                     DFTLEKGVYSKFALLDGTVKEELEDKELSERGRYLKSVDRYKAMLNA"
BASE COUNT          103 a           44 c           65 g           62 t
ORIGIN      
        1 aatttaaaga tatagctgaa aaattgccag aattagaggg taagcgtcta gaagaaatta
       61 ctaaagtatt aggttaccgt aacctagaga gttgcagaac caacctctgc aagctgaaac
      121 aaaacaatcg cctagatttt acactagaaa aaggagttta tagcaagttc gcactcttgg
      181 acggtacggt aaaagaggaa ttggaagata aagaattgtc agaacgtggg cgctatttga
      241 agagcgtaga ccgctacaag gcaatgctga atgc
//
LOCUS       DAVHLA010000111          261 bp    DNA     linear   BCT 17-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain SP21
            SAMN04504902-rid19297763.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVHLA010000111 DAVHLA010000000
VERSION     DAVHLA010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04504902
            Sequence Read Archive: SRR3211697
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 261)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 261)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 31-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001869534.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001869534.1
            Genome Coverage       :: 207x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/31/2023 15:54:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,180
            CDSs (total)                      :: 2,137
            Genes (coding)                    :: 2,019
            CDSs (with protein)               :: 2,019
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 54 of 118
            Pseudo Genes (incomplete)         :: 57 of 118
            Pseudo Genes (internal stop)      :: 34 of 118
            Pseudo Genes (multiple problems)  :: 24 of 118
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..261
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04504902-rid19297763.denovo.111"
                     /strain="SP21"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Ontario"
                     /collected_by="Public Health Ontario"
     gene            complement(<1..>261)
                     /locus_tag="VVO77_002180"
     CDS             complement(<1..>261)
                     /locus_tag="VVO77_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU5694108.1"
                     /translation="VDIDSTHFTTYGKQEGVAYNAHYRAHGYHPLYAFEGKTGYCFNA
                     QLRPGNRYCSEEADSFITPVLERFNQLLFRMDSGFATPKLYD"
BASE COUNT           87 a           52 c           57 g           65 t
ORIGIN      
        1 aatcgtataa ttttggggtc gcaaagccac tatccattcg aaagagaagt tgattaaacc
       61 gttctaaaac aggtgtgata aagctgtctg cctcttcaga acaataacga ttaccaggac
      121 gaagctgggc attgaaacaa taacctgtct tcccctcgaa agcataaaga ggatgatagc
      181 catgagcacg atagtgggcg ttataagcaa caccttcttg cttgccataa gttgtgaaat
      241 gggtagaatc gatatctaca a
//
